IMP: Integrative Multi-species Prediction

Homo sapiens

380 genes annotated in human

cellular macromolecule catabolic process

The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular macromolecule catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular macromolecule catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
UBC	ubiquitin C	1.000
TP53	tumor protein p53	1.000
RNF11	ring finger protein 11	1.000
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	1.000
XIAP	X-linked inhibitor of apoptosis	1.000	Human
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	1.000	Human Yeast
SKP1	S-phase kinase-associated protein 1	1.000
VCP	valosin containing protein	1.000
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	1.000
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	1.000	Fly
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	1.000	Yeast
BRCA1	breast cancer 1, early onset	0.999
PABPC1	poly(A) binding protein, cytoplasmic 1	0.999
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.999
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.999
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.999	Yeast
SKP2	S-phase kinase-associated protein 2 (p45)	0.998	Mouse
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.998
CUL1	cullin 1	0.998
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.998	Yeast
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.998	Yeast Worm
CUL3	cullin 3	0.997
EXOSC3	exosome component 3	0.997
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.997
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.996
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.995
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.994	Human Mouse
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.994
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.992
HSPA8	heat shock 70kDa protein 8	0.991	Human
SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	0.991
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.991	Yeast
RBM8A	RNA binding motif protein 8A	0.991
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.989	Yeast
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.988
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.988
BIRC2	baculoviral IAP repeat containing 2	0.987
PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	0.985	Yeast Mouse
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.985	Yeast
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.981	Yeast
CCNA2	cyclin A2	0.978
PTK2	PTK2 protein tyrosine kinase 2	0.974	Human Mouse
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.974
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.973
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.973
UPF3A	UPF3 regulator of nonsense transcripts homolog A (yeast)	0.972	Human Worm
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.972
FBXW11	F-box and WD repeat domain containing 11	0.970
EXOSC4	exosome component 4	0.965
CUL2	cullin 2	0.965	Worm
TNRC6A	trinucleotide repeat containing 6A	0.963	Human
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.963
EXOSC10	exosome component 10	0.963
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.961	Yeast
ARIH2	ariadne homolog 2 (Drosophila)	0.958
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.955
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.953
ANAPC4	anaphase promoting complex subunit 4	0.952
SNX9	sorting nexin 9	0.950
BIRC3	baculoviral IAP repeat containing 3	0.950	Human
UBE3A	ubiquitin protein ligase E3A	0.947	Mouse Fly
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.945	Yeast
BTRC	beta-transducin repeat containing	0.941
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.941
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.939
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.939
QKI	quaking homolog, KH domain RNA binding (mouse)	0.939
CCNB1	cyclin B1	0.938
RB1	retinoblastoma 1	0.933
VHL	von Hippel-Lindau tumor suppressor	0.932	Mouse
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.932
DIS3L	DIS3 mitotic control homolog (S. cerevisiae)-like	0.924
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.924
RAD23B	RAD23 homolog B (S. cerevisiae)	0.923
HUWE1	HECT, UBA and WWE domain containing 1	0.923	Human Yeast
SMAD4	SMAD family member 4	0.920	Human
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.920
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.918
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.917	Human
PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.917
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.914	Yeast
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.913
POMP	proteasome maturation protein	0.911
DERL1	Der1-like domain family, member 1	0.909
TNRC6C	trinucleotide repeat containing 6C	0.898
TSG101	tumor susceptibility gene 101	0.897
MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	0.896	Yeast
PDCD6IP	programmed cell death 6 interacting protein	0.894
TRIM39	tripartite motif containing 39	0.894
TRAF6	TNF receptor-associated factor 6	0.890
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.887
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.885	Yeast
RNF111	ring finger protein 111	0.883	Mouse
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.882	Yeast
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.879	Yeast Fly
UPF3B	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.874
RNF5	ring finger protein 5	0.873
CDT1	chromatin licensing and DNA replication factor 1	0.872
UBQLN1	ubiquilin 1	0.871	Human
FAF2	Fas associated factor family member 2	0.870
DAXX	death-domain associated protein	0.862
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.861
ANAPC5	anaphase promoting complex subunit 5	0.858
SMAD2	SMAD family member 2	0.857	Human
SOCS1	suppressor of cytokine signaling 1	0.853	Human
CDK2	cyclin-dependent kinase 2	0.852	Yeast
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.852
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.847
TOB1	transducer of ERBB2, 1	0.845
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.842	Fly
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.839
SQSTM1	sequestosome 1	0.838
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.837	Human Mouse Fly
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.836
BCL2	B-cell CLL/lymphoma 2	0.835	Human
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.835
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.833	Mouse Fly
FBXO33	F-box protein 33	0.831
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.824
UBXN7	UBX domain protein 7	0.822	Yeast
TADA3	transcriptional adaptor 3	0.820
PJA2	praja ring finger 2	0.818
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.817
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	0.812	Human
RPL11	ribosomal protein L11	0.811
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.810	Zebrafish
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.805	Yeast
EXOSC7	exosome component 7	0.801	Yeast
PPP5C	protein phosphatase 5, catalytic subunit	0.801
HSPA4	heat shock 70kDa protein 4	0.799
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.795
PLK1	polo-like kinase 1	0.792
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.791
APTX	aprataxin	0.791
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.790
GSK3B	glycogen synthase kinase 3 beta	0.789	Mouse Fly
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.784
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.783	Worm
SMAD1	SMAD family member 1	0.783	Human
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.779
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.779
HSPA1A	heat shock 70kDa protein 1A	0.770
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.770
TRIM27	tripartite motif containing 27	0.770	Human
CREBBP	CREB binding protein	0.770
SMAD3	SMAD family member 3	0.765	Human
UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)	0.754
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.752	Human Yeast Fly
RNF20	ring finger protein 20	0.750
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.744	Human
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.743
TRIM28	tripartite motif containing 28	0.743
RBL1	retinoblastoma-like 1 (p107)	0.739	Human
SNW1	SNW domain containing 1	0.739
OPTN	optineurin	0.737
PSMB3	proteasome (prosome, macropain) subunit, beta type, 3	0.737	Yeast
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.734	Human
NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	0.733
PARP1	poly (ADP-ribose) polymerase 1	0.733
USP15	ubiquitin specific peptidase 15	0.730	Human
FBXO5	F-box protein 5	0.730
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.728
CSNK1A1	casein kinase 1, alpha 1	0.728	Fly
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.725
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.724
EXOSC2	exosome component 2	0.723	Yeast
HSPA1B	heat shock 70kDa protein 1B	0.723
FBXW2	F-box and WD repeat domain containing 2	0.720
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.713
PSMB4	proteasome (prosome, macropain) subunit, beta type, 4	0.713	Yeast
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.711
TNRC6B	trinucleotide repeat containing 6B	0.709
HSPA13	heat shock protein 70kDa family, member 13	0.706
CUL5	cullin 5	0.705
UBXN1	UBX domain protein 1	0.704
ANAPC7	anaphase promoting complex subunit 7	0.701
ATXN1	ataxin 1	0.700
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.699
SELS	selenoprotein S	0.695
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.694
EPS15	epidermal growth factor receptor pathway substrate 15	0.692
CNOT7	CCR4-NOT transcription complex, subunit 7	0.688
AURKB	aurora kinase B	0.688
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.685	Yeast Mouse
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.682
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.680	Yeast
RIPK2	receptor-interacting serine-threonine kinase 2	0.680	Human
PRKCA	protein kinase C, alpha	0.679
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.679
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.678	Mouse
RFWD2	ring finger and WD repeat domain 2	0.678
EXOSC5	exosome component 5	0.672
CPEB4	cytoplasmic polyadenylation element binding protein 4	0.672	Human
TRIM43	tripartite motif containing 43	0.672
ANAPC11	anaphase promoting complex subunit 11	0.670	Yeast
ERH	enhancer of rudimentary homolog (Drosophila)	0.669
NCF1	neutrophil cytosolic factor 1	0.656
BAG6	BCL2-associated athanogene 6	0.655	Mouse
RYBP	RING1 and YY1 binding protein	0.655	Fly
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.654	Human
E2F1	E2F transcription factor 1	0.652
EIF2C4	eukaryotic translation initiation factor 2C, 4	0.648
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.648	Yeast Mouse
COPS3	COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)	0.645	Worm
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.642
CUL4A	cullin 4A	0.637	Mouse
MAPK6	mitogen-activated protein kinase 6	0.636
EP300	E1A binding protein p300	0.636
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.636
PAIP2	poly(A) binding protein interacting protein 2	0.630
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.630
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.629
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.626
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.625
ZNRF1	zinc and ring finger 1	0.624	Mouse
DICER1	dicer 1, ribonuclease type III	0.619	Worm
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.617	Yeast
RPL8	ribosomal protein L8	0.610
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.608	Mouse
SMAD7	SMAD family member 7	0.601
RNF2	ring finger protein 2	0.600
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.599	Human Mouse Fly
ETF1	eukaryotic translation termination factor 1	0.594
TARDBP	TAR DNA binding protein	0.593
ASF1A	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)	0.590
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.590
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	0.589
RBBP8	retinoblastoma binding protein 8	0.585
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.582
SMC6	structural maintenance of chromosomes 6	0.581
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.576	Human
CNOT3	CCR4-NOT transcription complex, subunit 3	0.573	Yeast
EIF4A3	eukaryotic translation initiation factor 4A3	0.571
FBXW7	F-box and WD repeat domain containing 7	0.570
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.570	Mouse
PCBP2	poly(rC) binding protein 2	0.565
COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.562
RAD50	RAD50 homolog (S. cerevisiae)	0.561
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.560
MED15	mediator complex subunit 15	0.560
PSAP	prosaposin	0.559
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.554
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.553	Human
FEN1	flap structure-specific endonuclease 1	0.553
POU5F1	POU class 5 homeobox 1	0.551
CARM1	coactivator-associated arginine methyltransferase 1	0.546
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.545
SETDB1	SET domain, bifurcated 1	0.542
KLHL12	kelch-like 12 (Drosophila)	0.540	Human
PTEN	phosphatase and tensin homolog	0.540
RNF7	ring finger protein 7	0.540
H2AFX	H2A histone family, member X	0.537
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.535
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.533	Yeast
PCNA	proliferating cell nuclear antigen	0.531
ZWINT	ZW10 interactor	0.529
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.523
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.521	Human
ATF3	activating transcription factor 3	0.521
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.520
AMFR	autocrine motility factor receptor	0.515
RNF126	ring finger protein 126	0.512
CNOT6	CCR4-NOT transcription complex, subunit 6	0.511
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.508	Human
YBX1	Y box binding protein 1	0.508
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.507	Human
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.507
SIAH1	seven in absentia homolog 1 (Drosophila)	0.506
TRIM21	tripartite motif containing 21	0.502	Human
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.499	Yeast
MED1	mediator complex subunit 1	0.499
MIB1	mindbomb homolog 1 (Drosophila)	0.498
MKRN1	makorin ring finger protein 1	0.498
EXO1	exonuclease 1	0.494
CNOT6L	CCR4-NOT transcription complex, subunit 6-like	0.492	Human Yeast Mouse
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.490
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.487
SMAD5	SMAD family member 5	0.485	Human
CNOT8	CCR4-NOT transcription complex, subunit 8	0.482
NBR1	neighbor of BRCA1 gene 1	0.482
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.477
CTAG1B	cancer/testis antigen 1B	0.475
VIM	vimentin	0.472
NBN	nibrin	0.471
CAND1	cullin-associated and neddylation-dissociated 1	0.469
HDAC1	histone deacetylase 1	0.468
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.468
PIAS4	protein inhibitor of activated STAT, 4	0.468
SKIV2L2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	0.467	Yeast
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.465
CUL4B	cullin 4B	0.464
CNOT1	CCR4-NOT transcription complex, subunit 1	0.464
SH3RF1	SH3 domain containing ring finger 1	0.458	Fly
TEKT4	tektin 4	0.457
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.455
CSNK1E	casein kinase 1, epsilon	0.450	Mouse Fly
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.450
SPOP	speckle-type POZ protein	0.448
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.447
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.446
ADRM1	adhesion regulating molecule 1	0.446
RBL2	retinoblastoma-like 2 (p130)	0.445	Human
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.443
ESR1	estrogen receptor 1	0.441
CDK1	cyclin-dependent kinase 1	0.441	Yeast
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.440
SEL1L	sel-1 suppressor of lin-12-like (C. elegans)	0.439
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.438
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.438
GFM1	G elongation factor, mitochondrial 1	0.432
PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.432	Yeast Mouse
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.432
RNF168	ring finger protein 168	0.432
TRIM63	tripartite motif containing 63	0.431	Human Mouse
EME1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	0.430
YY1	YY1 transcription factor	0.430
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.425
DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)	0.425
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.424	Human
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.422
UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)	0.420
KRT15	keratin 15	0.419
ATXN3	ataxin 3	0.414	Mouse
EEF2	eukaryotic translation elongation factor 2	0.413
SEC24B	SEC24 family, member B (S. cerevisiae)	0.412
SART3	squamous cell carcinoma antigen recognized by T cells 3	0.411
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.410
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.410
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.409
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.409	Yeast Mouse
DFFA	DNA fragmentation factor, 45kDa, alpha polypeptide	0.409
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.407	Human Yeast
TRIM37	tripartite motif containing 37	0.406
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.406	Human
MED28	mediator complex subunit 28	0.405
DIS3	DIS3 mitotic control homolog (S. cerevisiae)	0.404
DIABLO	diablo, IAP-binding mitochondrial protein	0.403
CCT2	chaperonin containing TCP1, subunit 2 (beta)	0.401
KDM1A	lysine (K)-specific demethylase 1A	0.398
MAGEA3	melanoma antigen family A, 3	0.398
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.395
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.395	Yeast
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.393
CSTF2	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	0.389
MARCH7	membrane-associated ring finger (C3HC4) 7	0.389
MBD3	methyl-CpG binding domain protein 3	0.387
WDR26	WD repeat domain 26	0.386
EIF3G	eukaryotic translation initiation factor 3, subunit G	0.383
CNOT2	CCR4-NOT transcription complex, subunit 2	0.381	Fly
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.380
CCND1	cyclin D1	0.378
GABARAPL1	GABA(A) receptor-associated protein like 1	0.378
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.377
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.377
UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	0.374	Yeast Mouse
BARD1	BRCA1 associated RING domain 1	0.371
FAS	Fas (TNF receptor superfamily, member 6)	0.369
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.368
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.364
RNF38	ring finger protein 38	0.361
GFI1B	growth factor independent 1B transcription repressor	0.360
USP8	ubiquitin specific peptidase 8	0.356	Yeast
RNF144B	ring finger protein 144B	0.353
UBQLN2	ubiquilin 2	0.350	Human
PTTG1	pituitary tumor-transforming 1	0.349
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	0.349
FOXM1	forkhead box M1	0.348
CDC40	cell division cycle 40 homolog (S. cerevisiae)	0.347
DCP1B	DCP1 decapping enzyme homolog B (S. cerevisiae)	0.346
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.342
UBA1	ubiquitin-like modifier activating enzyme 1	0.342
COIL	coilin	0.339
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.338
BCAR1	breast cancer anti-estrogen resistance 1	0.338
EIF3I	eukaryotic translation initiation factor 3, subunit I	0.338
UBXN2A	UBX domain protein 2A	0.338
CCNE2	cyclin E2	0.337	Fly
PRMT6	protein arginine methyltransferase 6	0.336
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.333
DDB1	damage-specific DNA binding protein 1, 127kDa	0.333
ANXA7	annexin A7	0.332
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.331
TIAL1	TIA1 cytotoxic granule-associated RNA binding protein-like 1	0.331	Yeast
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.331	Human
C11orf58	chromosome 11 open reading frame 58	0.329
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.327
EIF4E	eukaryotic translation initiation factor 4E	0.326
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	0.325
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.325
NCAM1	neural cell adhesion molecule 1	0.324
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.324
TRIP13	thyroid hormone receptor interactor 13	0.323
COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	0.322
PAIP1	poly(A) binding protein interacting protein 1	0.319
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.319
PCBP1	poly(rC) binding protein 1	0.316	Human
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.316	Mouse
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.316
SNRPC	small nuclear ribonucleoprotein polypeptide C	0.315
RNF14	ring finger protein 14	0.313
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.312
ANKRD13A	ankyrin repeat domain 13A	0.311
TERT	telomerase reverse transcriptase	0.310
EDC3	enhancer of mRNA decapping 3 homolog (S. cerevisiae)	0.308
CHD4	chromodomain helicase DNA binding protein 4	0.308
RDBP	RD RNA binding protein	0.306
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.303
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.303
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.303
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	0.301
FUBP1	far upstream element (FUSE) binding protein 1	0.301
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.299
ARRB2	arrestin, beta 2	0.298
TRAF4	TNF receptor-associated factor 4	0.296
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	0.296
TCP1	t-complex 1	0.294
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.294
ORC2	origin recognition complex, subunit 2	0.294
RAD51C	RAD51 homolog C (S. cerevisiae)	0.292
TUBB	tubulin, beta	0.291
EPOR	erythropoietin receptor	0.289
SOCS2	suppressor of cytokine signaling 2	0.288	Human
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.287	Mouse
SSR1	signal sequence receptor, alpha	0.287
FBXW5	F-box and WD repeat domain containing 5	0.286
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.285
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.285
RAD18	RAD18 homolog (S. cerevisiae)	0.282
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.282	Yeast
USP9X	ubiquitin specific peptidase 9, X-linked	0.281	Fly
BAK1	BCL2-antagonist/killer 1	0.281	Human
DNM2	dynamin 2	0.278
EIF1B	eukaryotic translation initiation factor 1B	0.277
FBXO3	F-box protein 3	0.276
EXOSC8	exosome component 8	0.275
TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	0.274
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.274
RNF10	ring finger protein 10	0.273
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.273
LRRK2	leucine-rich repeat kinase 2	0.272	Mouse
KIF5B	kinesin family member 5B	0.272
PXN	paxillin	0.271	Human
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.270
BAG2	BCL2-associated athanogene 2	0.270
BAX	BCL2-associated X protein	0.269
ACTB	actin, beta	0.269
FXR2	fragile X mental retardation, autosomal homolog 2	0.269
WAC	WW domain containing adaptor with coiled-coil	0.268
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.267
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.267
LIG4	ligase IV, DNA, ATP-dependent	0.266
UBASH3B	ubiquitin associated and SH3 domain containing B	0.266
AXIN1	axin 1	0.265	Mouse Rat
ECSIT	ECSIT homolog (Drosophila)	0.265
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.264	Yeast
DFFB	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	0.263
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.263
APAF1	apoptotic peptidase activating factor 1	0.262	Mouse
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.262	Yeast
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.262	Human Mouse
ZNF496	zinc finger protein 496	0.259
NCK2	NCK adaptor protein 2	0.258
CD44	CD44 molecule (Indian blood group)	0.257
CHMP1A	chromatin modifying protein 1A	0.257
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.256	Fly
HDAC11	histone deacetylase 11	0.255
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.255
TRIM5	tripartite motif containing 5	0.253	Human
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.252
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.252	Yeast
CKS2	CDC28 protein kinase regulatory subunit 2	0.252	Fly
FBXL15	F-box and leucine-rich repeat protein 15	0.252
TRIM32	tripartite motif containing 32	0.251
CTTN	cortactin	0.251
EID2	EP300 interacting inhibitor of differentiation 2	0.251
LIN28B	lin-28 homolog B (C. elegans)	0.250
IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	0.250
DCAF7	DDB1 and CUL4 associated factor 7	0.248
EID1	EP300 interacting inhibitor of differentiation 1	0.247
ING2	inhibitor of growth family, member 2	0.247
TRIM8	tripartite motif containing 8	0.246	Yeast
AXIN2	axin 2	0.246
MTA1	metastasis associated 1	0.245
CCPG1	cell cycle progression 1	0.244
CHD3	chromodomain helicase DNA binding protein 3	0.243
PDIA6	protein disulfide isomerase family A, member 6	0.243
KCTD10	potassium channel tetramerisation domain containing 10	0.243	Human
CFLAR	CASP8 and FADD-like apoptosis regulator	0.242
CDKN3	cyclin-dependent kinase inhibitor 3	0.242
SEC61G	Sec61 gamma subunit	0.241
CHFR	checkpoint with forkhead and ring finger domains	0.241
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.240
SRRM2	serine/arginine repetitive matrix 2	0.240
RMND5A	required for meiotic nuclear division 5 homolog A (S. cerevisiae)	0.240
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.237
USP34	ubiquitin specific peptidase 34	0.237
ANAPC1	anaphase promoting complex subunit 1	0.236	Worm Fly
TRIM71	tripartite motif containing 71	0.236	Human
CEP55	centrosomal protein 55kDa	0.236
BRAP	BRCA1 associated protein	0.236
HERC2	hect domain and RLD 2	0.236
RAD1	RAD1 homolog (S. pombe)	0.235
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.235
EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	0.235
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.234	Mouse
LNX1	ligand of numb-protein X 1	0.233	Mouse
IPO5	importin 5	0.232
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.231
NAP1L5	nucleosome assembly protein 1-like 5	0.231
CSDE1	cold shock domain containing E1, RNA-binding	0.227
UBE2C	ubiquitin-conjugating enzyme E2C	0.227
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.227
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.225
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.225
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.224
XAB2	XPA binding protein 2	0.223
LRR1	leucine rich repeat protein 1	0.222
SORBS3	sorbin and SH3 domain containing 3	0.222
MED21	mediator complex subunit 21	0.222
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.221
HIPK3	homeodomain interacting protein kinase 3	0.221
APP	amyloid beta (A4) precursor protein	0.220
MAP1S	microtubule-associated protein 1S	0.220
RNF114	ring finger protein 114	0.219
BTG1	B-cell translocation gene 1, anti-proliferative	0.219	Human
ADRBK1	adrenergic, beta, receptor kinase 1	0.218
DAPK1	death-associated protein kinase 1	0.217
FADD	Fas (TNFRSF6)-associated via death domain	0.217
CANX	calnexin	0.217
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.216
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.216
FBXO7	F-box protein 7	0.214
MAPK9	mitogen-activated protein kinase 9	0.213
RAD23A	RAD23 homolog A (S. cerevisiae)	0.211
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.211
AFF4	AF4/FMR2 family, member 4	0.211
PPM1G	protein phosphatase, Mg2+/Mn2+ dependent, 1G	0.211
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.210
CD2	CD2 molecule	0.210
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.210
POP4	processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae)	0.209
DDIT4	DNA-damage-inducible transcript 4	0.209
UBE2S	ubiquitin-conjugating enzyme E2S	0.209
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.207
ZNF263	zinc finger protein 263	0.207
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.207
PRNP	prion protein	0.206
IRF1	interferon regulatory factor 1	0.205
BIRC6	baculoviral IAP repeat containing 6	0.204
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.204	Yeast
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.204	Yeast
ALG6	asparagine-linked glycosylation 6, alpha-1,3-glucosyltransferase homolog (S. cerevisiae)	0.204
SH3KBP1	SH3-domain kinase binding protein 1	0.203
ZYG11B	zyg-11 homolog B (C. elegans)	0.203
APIP	APAF1 interacting protein	0.203
VTA1	Vps20-associated 1 homolog (S. cerevisiae)	0.203
STRN3	striatin, calmodulin binding protein 3	0.203
RNF4	ring finger protein 4	0.202
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.202	Human
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.202
CBX8	chromobox homolog 8	0.201
ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)	0.201
USP25	ubiquitin specific peptidase 25	0.201
BABAM1	BRISC and BRCA1 A complex member 1	0.200
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.200	Yeast
PUF60	poly-U binding splicing factor 60KDa	0.200
PPME1	protein phosphatase methylesterase 1	0.200
C20orf94	chromosome 20 open reading frame 94	0.199
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.199
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.198	Human
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.197
CLOCK	clock homolog (mouse)	0.196	Mouse
SRGN	serglycin	0.196
C1QBP	complement component 1, q subcomponent binding protein	0.195
TUBA1B	tubulin, alpha 1b	0.194
CACYBP	calcyclin binding protein	0.194
SRPK2	SRSF protein kinase 2	0.193
MARCH5	membrane-associated ring finger (C3HC4) 5	0.193
BTG2	BTG family, member 2	0.193
EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	0.193
MAGOHB	mago-nashi homolog B (Drosophila)	0.193	Human
RHOB	ras homolog gene family, member B	0.192
NSFL1C	NSFL1 (p97) cofactor (p47)	0.192	Yeast
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.192
EXOSC1	exosome component 1	0.191	Yeast
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.191
VPRBP	Vpr (HIV-1) binding protein	0.191
KEAP1	kelch-like ECH-associated protein 1	0.190
SIAH2	seven in absentia homolog 2 (Drosophila)	0.190
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.190	Yeast
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.190
TLK1	tousled-like kinase 1	0.190	Human
MSH3	mutS homolog 3 (E. coli)	0.189	Yeast
BAG3	BCL2-associated athanogene 3	0.188
PGAM5	phosphoglycerate mutase family member 5	0.188
SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2	0.188
BFAR	bifunctional apoptosis regulator	0.187
MED6	mediator complex subunit 6	0.187
PHF20L1	PHD finger protein 20-like 1	0.187
ZNF451	zinc finger protein 451	0.186
TAF7	TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa	0.185
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.185	Human Mouse
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.184
PCM1	pericentriolar material 1	0.184
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.184	Mouse
CCAR1	cell division cycle and apoptosis regulator 1	0.184
ATF5	activating transcription factor 5	0.182
FBXL5	F-box and leucine-rich repeat protein 5	0.182
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.182
IPO8	importin 8	0.182
FIGNL1	fidgetin-like 1	0.181
CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	0.181
PIAS1	protein inhibitor of activated STAT, 1	0.181	Mouse
UBXN6	UBX domain protein 6	0.180
TXN	thioredoxin	0.180
DERL2	Der1-like domain family, member 2	0.180
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.180
KLHL20	kelch-like 20 (Drosophila)	0.180
ZNF746	zinc finger protein 746	0.180
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.179	Human
FBXO4	F-box protein 4	0.179
NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive	0.179
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.178
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.178
GRSF1	G-rich RNA sequence binding factor 1	0.178
CASP8AP2	caspase 8 associated protein 2	0.178
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.177
RARA	retinoic acid receptor, alpha	0.177
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.177
OXSR1	oxidative-stress responsive 1	0.177
TH1L	TH1-like (Drosophila)	0.176
NCL	nucleolin	0.175
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.175
PSEN1	presenilin 1	0.175	Mouse
GATAD2B	GATA zinc finger domain containing 2B	0.175
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.175
HP	haptoglobin	0.174
WT1	Wilms tumor 1	0.174
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.174
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.174
RING1	ring finger protein 1	0.173
XRCC1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.171
MYO1C	myosin IC	0.171
GCLM	glutamate-cysteine ligase, modifier subunit	0.170
FHL2	four and a half LIM domains 2	0.170
GATAD2A	GATA zinc finger domain containing 2A	0.167
FANCD2	Fanconi anemia, complementation group D2	0.167
CCL3	chemokine (C-C motif) ligand 3	0.166
SOD1	superoxide dismutase 1, soluble	0.166
NEURL4	neuralized homolog 4 (Drosophila)	0.166
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.166
DTX3L	deltex 3-like (Drosophila)	0.166
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.165	Human
MYD88	myeloid differentiation primary response gene (88)	0.165
HSPH1	heat shock 105kDa/110kDa protein 1	0.164
ANKRD17	ankyrin repeat domain 17	0.164
RIPK3	receptor-interacting serine-threonine kinase 3	0.163	Human
SPAG9	sperm associated antigen 9	0.163
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.163
YAP1	Yes-associated protein 1	0.162
DCTN4	dynactin 4 (p62)	0.162
SESN2	sestrin 2	0.162
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	0.162
XPC	xeroderma pigmentosum, complementation group C	0.161
TRIM25	tripartite motif containing 25	0.161
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.161
RNASE4	ribonuclease, RNase A family, 4	0.161
SNRPD1	small nuclear ribonucleoprotein D1 polypeptide 16kDa	0.160
PPP1CB	protein phosphatase 1, catalytic subunit, beta isozyme	0.160
MIS18BP1	MIS18 binding protein 1	0.160
TOPBP1	topoisomerase (DNA) II binding protein 1	0.160
ARPP19	cAMP-regulated phosphoprotein, 19kDa	0.159
CCT3	chaperonin containing TCP1, subunit 3 (gamma)	0.159
TMEM66	transmembrane protein 66	0.159
DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10	0.158
BMI1	BMI1 polycomb ring finger oncogene	0.158
BBS10	Bardet-Biedl syndrome 10	0.158
PDPK1	3-phosphoinositide dependent protein kinase-1	0.158	Yeast
OTUD4	OTU domain containing 4	0.157
ERCC4	excision repair cross-complementing rodent repair deficiency, complementation group 4	0.157
IFI16	interferon, gamma-inducible protein 16	0.156
ZFAND5	zinc finger, AN1-type domain 5	0.156
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.156
FAF1	Fas (TNFRSF6) associated factor 1	0.155
BCLAF1	BCL2-associated transcription factor 1	0.155
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.155
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.155	Human
PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.155
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.155
MED13	mediator complex subunit 13	0.154
RNF181	ring finger protein 181	0.154
EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	0.154
NOXA1	NADPH oxidase activator 1	0.154
ERBB2IP	erbb2 interacting protein	0.153
GTF2A2	general transcription factor IIA, 2, 12kDa	0.153
PABPC3	poly(A) binding protein, cytoplasmic 3	0.153	Human Yeast
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.152
STIL	SCL/TAL1 interrupting locus	0.152
DHPS	deoxyhypusine synthase	0.152
RGS2	regulator of G-protein signaling 2, 24kDa	0.151
NCAPG	non-SMC condensin I complex, subunit G	0.151
LIMS1	LIM and senescent cell antigen-like domains 1	0.150	Human
MBD4	methyl-CpG binding domain protein 4	0.150
STOML2	stomatin (EPB72)-like 2	0.149
DTX2	deltex homolog 2 (Drosophila)	0.149
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.147
ACD	adrenocortical dysplasia homolog (mouse)	0.147
EIF5	eukaryotic translation initiation factor 5	0.147
PSEN2	presenilin 2 (Alzheimer disease 4)	0.146	Mouse
UBXN4	UBX domain protein 4	0.146
SHPRH	SNF2 histone linker PHD RING helicase	0.146
NUDCD3	NudC domain containing 3	0.145
GBP1	guanylate binding protein 1, interferon-inducible	0.145
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.145
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.145
RNF31	ring finger protein 31	0.144
FNTA	farnesyltransferase, CAAX box, alpha	0.144
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.144
C4orf14	chromosome 4 open reading frame 14	0.144
POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	0.144
RNF41	ring finger protein 41	0.144
TRIM33	tripartite motif containing 33	0.144
LRDD	leucine-rich repeats and death domain containing	0.143
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.143	Yeast
GLI1	GLI family zinc finger 1	0.143
BCL2L12	BCL2-like 12 (proline rich)	0.143
SAE1	SUMO1 activating enzyme subunit 1	0.142
RALY	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))	0.142	Yeast
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.141
UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)	0.141
HIST2H2AC	histone cluster 2, H2ac	0.141
FARSA	phenylalanyl-tRNA synthetase, alpha subunit	0.141
SRP54	signal recognition particle 54kDa	0.140
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.140
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.140
RAD54B	RAD54 homolog B (S. cerevisiae)	0.140
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.140
JAK2	Janus kinase 2	0.139
RNF146	ring finger protein 146	0.139
NEK6	NIMA (never in mitosis gene a)-related kinase 6	0.139
JUP	junction plakoglobin	0.139
TPBG	trophoblast glycoprotein	0.139
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.138
OPA1	optic atrophy 1 (autosomal dominant)	0.138
FBXO30	F-box protein 30	0.138
RIOK3	RIO kinase 3 (yeast)	0.138
BTBD10	BTB (POZ) domain containing 10	0.138
KCMF1	potassium channel modulatory factor 1	0.138
SRRM1	serine/arginine repetitive matrix 1	0.137
NCF4	neutrophil cytosolic factor 4, 40kDa	0.136