IMP: Integrative Multi-species Prediction

Homo sapiens

4 genes annotated in human

angiogenesis involved in wound healing

Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "angiogenesis involved in wound healing"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "angiogenesis involved in wound healing" (in gray)

Name	Description	Probability	Func Analog Organism
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	1.000
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	1.000
PLAU	plasminogen activator, urokinase	1.000
NRP1	neuropilin 1	1.000
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	1.000
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.999
COL4A1	collagen, type IV, alpha 1	0.999
PLAT	plasminogen activator, tissue	0.993
PDGFA	platelet-derived growth factor alpha polypeptide	0.977	Human
COL4A2	collagen, type IV, alpha 2	0.976
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.967
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.949	Human
COL5A1	collagen, type V, alpha 1	0.936
PLAUR	plasminogen activator, urokinase receptor	0.917
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.862
ENG	endoglin	0.813
PTPRB	protein tyrosine phosphatase, receptor type, B	0.803
PDGFC	platelet derived growth factor C	0.739
DAXX	death-domain associated protein	0.726
PLCG1	phospholipase C, gamma 1	0.672
THBS1	thrombospondin 1	0.601
COL6A1	collagen, type VI, alpha 1	0.590
SP100	SP100 nuclear antigen	0.580
COL1A1	collagen, type I, alpha 1	0.572
STC1	stanniocalcin 1	0.469
VEGFA	vascular endothelial growth factor A	0.450	Human
CYR61	cysteine-rich, angiogenic inducer, 61	0.443
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.439
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.433
PXDN	peroxidasin homolog (Drosophila)	0.419
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.301
COL1A2	collagen, type I, alpha 2	0.266
CDH5	cadherin 5, type 2 (vascular endothelium)	0.260
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.223
HSPG2	heparan sulfate proteoglycan 2	0.216
DDIT4	DNA-damage-inducible transcript 4	0.203
CAV1	caveolin 1, caveolae protein, 22kDa	0.202
LAMA5	laminin, alpha 5	0.181
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.176
SPHK1	sphingosine kinase 1	0.158
OSMR	oncostatin M receptor	0.154
TIMP3	TIMP metallopeptidase inhibitor 3	0.148
ANGPT2	angiopoietin 2	0.147
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.137
LDLR	low density lipoprotein receptor	0.127
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.127
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.126
TNC	tenascin C	0.118
IGFBP5	insulin-like growth factor binding protein 5	0.117
FZD4	frizzled homolog 4 (Drosophila)	0.115
COL3A1	collagen, type III, alpha 1	0.114
INHBA	inhibin, beta A	0.112
COL6A2	collagen, type VI, alpha 2	0.105
ORM1	orosomucoid 1	0.104
CSPG4	chondroitin sulfate proteoglycan 4	0.102
BHLHE40	basic helix-loop-helix family, member e40	0.096
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.086
VWF	von Willebrand factor	0.084
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.083
ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	0.079
VEGFC	vascular endothelial growth factor C	0.076	Human
TGFB1	transforming growth factor, beta 1	0.073
SRPX	sushi-repeat containing protein, X-linked	0.071
FLT4	fms-related tyrosine kinase 4	0.069
NRP2	neuropilin 2	0.068
TEK	TEK tyrosine kinase, endothelial	0.062
BGN	biglycan	0.059
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.058
IER3	immediate early response 3	0.054
EPAS1	endothelial PAS domain protein 1	0.053
CCL2	chemokine (C-C motif) ligand 2	0.053
FOSL2	FOS-like antigen 2	0.051
RFWD2	ring finger and WD repeat domain 2	0.051
ANGPTL4	angiopoietin-like 4	0.051
IGFBP4	insulin-like growth factor binding protein 4	0.050
EMCN	endomucin	0.050
ANGPTL2	angiopoietin-like 2	0.050
GJA4	gap junction protein, alpha 4, 37kDa	0.049
LRRC32	leucine rich repeat containing 32	0.049
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.048
COL18A1	collagen, type XVIII, alpha 1	0.047
GPRC5A	G protein-coupled receptor, family C, group 5, member A	0.046
NPC2	Niemann-Pick disease, type C2	0.046
FADS3	fatty acid desaturase 3	0.046
NNMT	nicotinamide N-methyltransferase	0.046
BCL3	B-cell CLL/lymphoma 3	0.045
COL16A1	collagen, type XVI, alpha 1	0.044
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.044
AXL	AXL receptor tyrosine kinase	0.042
COL2A1	collagen, type II, alpha 1	0.042
MCAM	melanoma cell adhesion molecule	0.041
WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	0.041
THBD	thrombomodulin	0.040
ESAM	endothelial cell adhesion molecule	0.039
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.039
FOSL1	FOS-like antigen 1	0.038
GPR116	G protein-coupled receptor 116	0.038
TGFB2	transforming growth factor, beta 2	0.037
NID1	nidogen 1	0.037
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.035
JAG1	jagged 1	0.034
LOXL2	lysyl oxidase-like 2	0.033
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.032
TGFB3	transforming growth factor, beta 3	0.031
IGFBP7	insulin-like growth factor binding protein 7	0.031
SPOP	speckle-type POZ protein	0.030
PPDPF	pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)	0.029
MYL9	myosin, light chain 9, regulatory	0.029
LTBP2	latent transforming growth factor beta binding protein 2	0.028
TFPI2	tissue factor pathway inhibitor 2	0.028
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.028
MMRN2	multimerin 2	0.027
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.027
CALCRL	calcitonin receptor-like	0.027
PALM	paralemmin	0.026
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.026
AEBP1	AE binding protein 1	0.026
CD248	CD248 molecule, endosialin	0.025
SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	0.025	Human
HBEGF	heparin-binding EGF-like growth factor	0.025
SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	0.025
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.024
ZNF358	zinc finger protein 358	0.024
MDFI	MyoD family inhibitor	0.024
TBX2	T-box 2	0.023
ACVRL1	activin A receptor type II-like 1	0.023
NID2	nidogen 2 (osteonidogen)	0.022
ICAM1	intercellular adhesion molecule 1	0.022
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.022
NOTCH4	notch 4	0.022
IL6	interleukin 6 (interferon, beta 2)	0.022
TAL1	T-cell acute lymphocytic leukemia 1	0.021
LAMB2	laminin, beta 2 (laminin S)	0.021
PCDH12	protocadherin 12	0.020
AES	amino-terminal enhancer of split	0.020
PDE2A	phosphodiesterase 2A, cGMP-stimulated	0.020
BMP4	bone morphogenetic protein 4	0.020
CD93	CD93 molecule	0.020
PECAM1	platelet/endothelial cell adhesion molecule	0.020
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	0.019
STC2	stanniocalcin 2	0.019
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.019
S1PR1	sphingosine-1-phosphate receptor 1	0.019
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.019
PVR	poliovirus receptor	0.019
VTN	vitronectin	0.019
TNS1	tensin 1	0.019
ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	0.019
CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	0.018
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.018
PML	promyelocytic leukemia	0.018
FGFR1	fibroblast growth factor receptor 1	0.018
EDN1	endothelin 1	0.017
ELTD1	EGF, latrophilin and seven transmembrane domain containing 1	0.017
EGFL7	EGF-like-domain, multiple 7	0.017
TGFBR1	transforming growth factor, beta receptor 1	0.017
RFNG	RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase	0.017
ENPEP	glutamyl aminopeptidase (aminopeptidase A)	0.017
PLVAP	plasmalemma vesicle associated protein	0.017
THY1	Thy-1 cell surface antigen	0.017
HEG1	HEG homolog 1 (zebrafish)	0.017
ADAMTS9	ADAM metallopeptidase with thrombospondin type 1 motif, 9	0.017
SLC2A3	solute carrier family 2 (facilitated glucose transporter), member 3	0.016
AQP1	aquaporin 1 (Colton blood group)	0.016
GAS6	growth arrest-specific 6	0.016
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.016
COL5A2	collagen, type V, alpha 2	0.016
USF2	upstream transcription factor 2, c-fos interacting	0.016
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.016
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.015
CSF1	colony stimulating factor 1 (macrophage)	0.015
LOX	lysyl oxidase	0.015
JAG2	jagged 2	0.015
EFNA1	ephrin-A1	0.015
PRRX1	paired related homeobox 1	0.015
ULBP2	UL16 binding protein 2	0.015
NT5E	5'-nucleotidase, ecto (CD73)	0.015
FST	follistatin	0.015
ECM1	extracellular matrix protein 1	0.015
ADM	adrenomedullin	0.015
RUNX1	runt-related transcription factor 1	0.015
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.015
DDIT3	DNA-damage-inducible transcript 3	0.015
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.014
SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)	0.014
TUBB6	tubulin, beta 6	0.014
LRP1	low density lipoprotein receptor-related protein 1	0.014
COL6A3	collagen, type VI, alpha 3	0.014
VAT1	vesicle amine transport protein 1 homolog (T. californica)	0.014
PODXL	podocalyxin-like	0.014
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.014
SEMA3G	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G	0.014
HAS2	hyaluronan synthase 2	0.014
DLC1	deleted in liver cancer 1	0.014
MYCT1	myc target 1	0.014
FURIN	furin (paired basic amino acid cleaving enzyme)	0.013
MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2	0.013
MMRN1	multimerin 1	0.013
PKN1	protein kinase N1	0.013
SORBS3	sorbin and SH3 domain containing 3	0.013
ESM1	endothelial cell-specific molecule 1	0.013
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.012
FNDC3B	fibronectin type III domain containing 3B	0.012
LBH	limb bud and heart development homolog (mouse)	0.012
GUCY1A3	guanylate cyclase 1, soluble, alpha 3	0.012
CSRNP1	cysteine-serine-rich nuclear protein 1	0.012
PMEPA1	prostate transmembrane protein, androgen induced 1	0.012
SMTN	smoothelin	0.012
COL7A1	collagen, type VII, alpha 1	0.012
SLC2A4RG	SLC2A4 regulator	0.012
GEM	GTP binding protein overexpressed in skeletal muscle	0.012
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.012
PDLIM4	PDZ and LIM domain 4	0.012
RAB11B	RAB11B, member RAS oncogene family	0.012
ECE1	endothelin converting enzyme 1	0.012
MFAP2	microfibrillar-associated protein 2	0.011
SDPR	serum deprivation response	0.011
RAI14	retinoic acid induced 14	0.011
GRB10	growth factor receptor-bound protein 10	0.011
CXCR7	chemokine (C-X-C motif) receptor 7	0.011
PHLDA2	pleckstrin homology-like domain, family A, member 2	0.011
STARD8	StAR-related lipid transfer (START) domain containing 8	0.011
EXT1	exostosin 1	0.011
GNG11	guanine nucleotide binding protein (G protein), gamma 11	0.011
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.011
RGS16	regulator of G-protein signaling 16	0.011
PROCR	protein C receptor, endothelial	0.011
RHOJ	ras homolog gene family, member J	0.011
ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.011
UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.010
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.010
CX3CL1	chemokine (C-X3-C motif) ligand 1	0.010
KIAA1462	KIAA1462	0.010
LOXL1	lysyl oxidase-like 1	0.010
MAP4	microtubule-associated protein 4	0.010
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.010
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.010
F3	coagulation factor III (thromboplastin, tissue factor)	0.010
OLFML2A	olfactomedin-like 2A	0.010