IMP
Process View
mitochondrial respiratory chain complex i biogenesis
The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.
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Click on a gene's description to view its network relationships with genes known to be involved in "mitochondrial respiratory chain complex i biogenesis"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.999 | ||
| NDUFS3 | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 0.854 | ||
| NDUFV1 | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 0.828 | ||
| NDUFA2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa | 0.815 | ||
| NDUFS2 | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 0.630 | ||
| ICT1 | immature colon carcinoma transcript 1 | 0.624 | ||
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 0.542 | ||
| CYC1 | cytochrome c-1 | 0.409 | ||
| NDUFA7 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa | 0.339 | ||
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.275 | ||
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 0.150 | ||
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | 0.149 | ||
| MRPL15 | mitochondrial ribosomal protein L15 | 0.133 | ||
| NDUFAF3 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3 | 0.128 | ||
| IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha | 0.105 | ||
| RTN4IP1 | reticulon 4 interacting protein 1 | 0.103 | ||
| NDUFA9 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 0.102 | ||
| SDHA | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 0.076 | ||
| MRPL35 | mitochondrial ribosomal protein L35 | 0.075 | ||
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa | 0.072 | ||
| DCXR | dicarbonyl/L-xylulose reductase | 0.069 | ||
| COQ9 | coenzyme Q9 homolog (S. cerevisiae) | 0.067 | ||
| COQ3 | coenzyme Q3 homolog, methyltransferase (S. cerevisiae) | 0.065 | ||
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa | 0.061 | ||
| GFM1 | G elongation factor, mitochondrial 1 | 0.059 | ||
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.055 | ||
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 0.050 | ||
| SCO1 | SCO cytochrome oxidase deficient homolog 1 (yeast) | 0.045 | ||
| ECI1 | enoyl-CoA delta isomerase 1 | 0.044 | ||
| C20orf7 | chromosome 20 open reading frame 7 | 0.042 | ||
| MRPL34 | mitochondrial ribosomal protein L34 | 0.042 | ||
| LYRM7 | Lyrm7 homolog (mouse) | 0.039 | ||
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | 0.037 | ||
| SAMM50 | sorting and assembly machinery component 50 homolog (S. cerevisiae) | 0.035 | ||
| APOO | apolipoprotein O | 0.035 | ||
| NDUFS6 | NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) | 0.035 | ||
| NDUFS1 | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 0.034 | ||
| C3orf1 | chromosome 3 open reading frame 1 | 0.034 | ||
| CYCS | cytochrome c, somatic | 0.032 | ||
| SFXN4 | sideroflexin 4 | 0.029 | ||
| MRPS11 | mitochondrial ribosomal protein S11 | 0.029 | ||
| NDUFAF1 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1 | 0.028 | ||
| MRPL32 | mitochondrial ribosomal protein L32 | 0.028 | ||
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 0.028 | ||
| TSFM | Ts translation elongation factor, mitochondrial | 0.026 | ||
| MIPEP | mitochondrial intermediate peptidase | 0.025 | ||
| C4orf14 | chromosome 4 open reading frame 14 | 0.025 | ||
| SURF1 | surfeit 1 | 0.025 | ||
| HADHA | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 0.024 | ||
| MGST3 | microsomal glutathione S-transferase 3 | 0.023 | ||
| OXNAD1 | oxidoreductase NAD-binding domain containing 1 | 0.023 | ||
| HIGD2A | HIG1 hypoxia inducible domain family, member 2A | 0.023 | ||
| UQCRFS1 | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 | 0.023 | ||
| MRPL46 | mitochondrial ribosomal protein L46 | 0.023 | ||
| NDUFA8 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa | 0.022 | ||
| ATP5B | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 0.022 | ||
| UQCRC2 | ubiquinol-cytochrome c reductase core protein II | 0.022 | ||
| NFS1 | NFS1 nitrogen fixation 1 homolog (S. cerevisiae) | 0.022 | ||
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 0.021 | ||
| MRPL16 | mitochondrial ribosomal protein L16 | 0.020 | ||
| AFG3L2 | AFG3 ATPase family gene 3-like 2 (S. cerevisiae) | 0.020 | ||
| MRPL10 | mitochondrial ribosomal protein L10 | 0.020 | ||
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.019 | ||
| NSUN5 | NOP2/Sun domain family, member 5 | 0.018 | ||
| PDHB | pyruvate dehydrogenase (lipoamide) beta | 0.017 | ||
| MRPL23 | mitochondrial ribosomal protein L23 | 0.017 | ||
| KAT2A | K(lysine) acetyltransferase 2A | 0.016 | ||
| PDHA1 | pyruvate dehydrogenase (lipoamide) alpha 1 | 0.015 | ||
| TMEM70 | transmembrane protein 70 | 0.015 | ||
| TMEM126A | transmembrane protein 126A | 0.015 | ||
| MRPL30 | mitochondrial ribosomal protein L30 | 0.015 | ||
| ATP5H | ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d | 0.015 | ||
| MRRF | mitochondrial ribosome recycling factor | 0.015 | ||
| WDR92 | WD repeat domain 92 | 0.015 | ||
| FAHD1 | fumarylacetoacetate hydrolase domain containing 1 | 0.014 | ||
| IDH3G | isocitrate dehydrogenase 3 (NAD+) gamma | 0.014 | ||
| MDH2 | malate dehydrogenase 2, NAD (mitochondrial) | 0.014 | ||
| C6orf203 | chromosome 6 open reading frame 203 | 0.014 | ||
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) | 0.013 | ||
| NDUFB9 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa | 0.013 | ||
| COX11 | COX11 cytochrome c oxidase assembly homolog (yeast) | 0.013 | ||
| APEH | N-acylaminoacyl-peptide hydrolase | 0.013 | ||
| C19orf56 | chromosome 19 open reading frame 56 | 0.013 | ||
| ERCC1 | excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) | 0.012 | ||
| C8orf38 | chromosome 8 open reading frame 38 | 0.012 | ||
| C18orf19 | chromosome 18 open reading frame 19 | 0.012 | ||
| GPX1 | glutathione peroxidase 1 | 0.012 | ||
| ARL2 | ADP-ribosylation factor-like 2 | 0.012 | ||
| MRPS9 | mitochondrial ribosomal protein S9 | 0.012 | ||
| LIAS | lipoic acid synthetase | 0.012 | ||
| ISOC1 | isochorismatase domain containing 1 | 0.011 | ||
| PET112L | PET112-like (yeast) | 0.011 | ||
| MRPL24 | mitochondrial ribosomal protein L24 | 0.011 | ||
| PREB | prolactin regulatory element binding | 0.011 | ||
| METTL17 | methyltransferase like 17 | 0.011 | ||
| MRPS7 | mitochondrial ribosomal protein S7 | 0.011 | ||
| MRPL1 | mitochondrial ribosomal protein L1 | 0.010 | ||
| TMEM186 | transmembrane protein 186 | 0.010 | ||
| SELRC1 | Sel1 repeat containing 1 | 0.010 |