IMP: Integrative Multi-species Prediction

Homo sapiens

142 genes annotated in human

positive regulation of proteolysis

Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of proteolysis"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of proteolysis" (in gray)

Name	Description	Probability	Func Analog Organism
MDM2	Mdm2 p53 binding protein homolog (mouse)	1.000
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.999
BCL2	B-cell CLL/lymphoma 2	0.999	Human
SMAD4	SMAD family member 4	0.999	Human
BCL2L1	BCL2-like 1	0.999	Human
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.997	Yeast
XIAP	X-linked inhibitor of apoptosis	0.993
RB1	retinoblastoma 1	0.991
FASLG	Fas ligand (TNF superfamily, member 6)	0.991
FYN	FYN oncogene related to SRC, FGR, YES	0.981	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.974	Human
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.960	Human
BAX	BCL2-associated X protein	0.956
TP53	tumor protein p53	0.951	Zebrafish Fly
SMAD1	SMAD family member 1	0.945	Human
SOCS1	suppressor of cytokine signaling 1	0.944	Human
TRAF2	TNF receptor-associated factor 2	0.910
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.903
FAS	Fas (TNF receptor superfamily, member 6)	0.902	Rat
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.898
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.894	Human Fly
SMAD3	SMAD family member 3	0.874
SKIL	SKI-like oncogene	0.872
SP1	Sp1 transcription factor	0.871
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.869
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.863	Human
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.861
BID	BH3 interacting domain death agonist	0.857	Mouse
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.853
PYCARD	PYD and CARD domain containing	0.849
UBQLN1	ubiquilin 1	0.836
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.834
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.831
HDAC1	histone deacetylase 1	0.821	Human
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.815	Human
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.805	Yeast Fly
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.803	Human
RIPK2	receptor-interacting serine-threonine kinase 2	0.777
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.773
CREBBP	CREB binding protein	0.754
CASP2	caspase 2, apoptosis-related cysteine peptidase	0.748	Human Fly
RAD23B	RAD23 homolog B (S. cerevisiae)	0.746
GSK3B	glycogen synthase kinase 3 beta	0.745	Mouse Fly
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.741
POU5F1	POU class 5 homeobox 1	0.734
PIAS4	protein inhibitor of activated STAT, 4	0.728
SMAD5	SMAD family member 5	0.710	Human
S100B	S100 calcium binding protein B	0.697	Human
UBC	ubiquitin C	0.679
PML	promyelocytic leukemia	0.676	Mouse
ZMYND11	zinc finger, MYND-type containing 11	0.674
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.665
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.654	Human
HMGB1	high mobility group box 1	0.652
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.646	Human Mouse
ESR1	estrogen receptor 1	0.643
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.618
PLK1	polo-like kinase 1	0.614
CSNK1E	casein kinase 1, epsilon	0.607	Mouse Fly
S100A6	S100 calcium binding protein A6	0.606	Human
BAD	BCL2-associated agonist of cell death	0.606
RNF11	ring finger protein 11	0.604
S100A9	S100 calcium binding protein A9	0.595
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.593
SMAD2	SMAD family member 2	0.593	Human
PSEN1	presenilin 1	0.576	Mouse
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.575
IL1R1	interleukin 1 receptor, type I	0.554
ADAM15	ADAM metallopeptidase domain 15	0.548
FGF1	fibroblast growth factor 1 (acidic)	0.540
AXIN1	axin 1	0.529	Mouse Rat
APAF1	apoptotic peptidase activating factor 1	0.526
CTGF	connective tissue growth factor	0.513	Rat
DAXX	death-domain associated protein	0.511
SNX9	sorting nexin 9	0.511
ANXA2	annexin A2	0.511
VHL	von Hippel-Lindau tumor suppressor	0.509
CAV1	caveolin 1, caveolae protein, 22kDa	0.507	Mouse
HCK	hemopoietic cell kinase	0.492	Human
SNX33	sorting nexin 33	0.484
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.483
TRAF5	TNF receptor-associated factor 5	0.469
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.467	Fly
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.463	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.448
NLRC4	NLR family, CARD domain containing 4	0.441
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.441
GRB2	growth factor receptor-bound protein 2	0.440
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.439
PTEN	phosphatase and tensin homolog	0.439
TRADD	TNFRSF1A-associated via death domain	0.432
S100A8	S100 calcium binding protein A8	0.426
S100A4	S100 calcium binding protein A4	0.406	Human
BRCA1	breast cancer 1, early onset	0.400
FADD	Fas (TNFRSF6)-associated via death domain	0.394
C4orf14	chromosome 4 open reading frame 14	0.392
FMR1	fragile X mental retardation 1	0.392
PRNP	prion protein	0.391
RPL11	ribosomal protein L11	0.388
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.387
PSEN2	presenilin 2 (Alzheimer disease 4)	0.385	Mouse
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.385
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.384
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.377	Human
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.377
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.374
CASP8AP2	caspase 8 associated protein 2	0.373
RARA	retinoic acid receptor, alpha	0.360
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.352	Human Fly
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.351	Yeast
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.340
SMN1	survival of motor neuron 1, telomeric	0.339
CFLAR	CASP8 and FADD-like apoptosis regulator	0.338	Mouse
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.329
TNF	tumor necrosis factor	0.328
SMAD7	SMAD family member 7	0.328
PAX3	paired box 3	0.324
CSNK1D	casein kinase 1, delta	0.322	Mouse Fly
CUL1	cullin 1	0.319
AURKA	aurora kinase A	0.317	Mouse
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.315
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.312
EZR	ezrin	0.309
NCL	nucleolin	0.304
CDK2	cyclin-dependent kinase 2	0.303
CXXC5	CXXC finger protein 5	0.303
EPAS1	endothelial PAS domain protein 1	0.301
CSNK1A1	casein kinase 1, alpha 1	0.288	Fly
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.288
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.287
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.285	Yeast
RBL1	retinoblastoma-like 1 (p107)	0.282	Human
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.281
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.280
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.280	Human
ANAPC4	anaphase promoting complex subunit 4	0.278
HSPA8	heat shock 70kDa protein 8	0.270
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.268
STIP1	stress-induced-phosphoprotein 1	0.265
AR	androgen receptor	0.265
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.262	Human
VDAC1	voltage-dependent anion channel 1	0.261
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.260
MPDZ	multiple PDZ domain protein	0.259
EIF4E	eukaryotic translation initiation factor 4E	0.255
NMI	N-myc (and STAT) interactor	0.255
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.254
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.253
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.253
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.252
TRAF1	TNF receptor-associated factor 1	0.247
GORAB	golgin, RAB6-interacting	0.245
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.242
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.239
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.239
POU3F2	POU class 3 homeobox 2	0.237
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.236
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.233
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.233	Mouse
ITK	IL2-inducible T-cell kinase	0.229
SQSTM1	sequestosome 1	0.229
CUL2	cullin 2	0.227
HMGB2	high mobility group box 2	0.226	Human
XAF1	XIAP associated factor 1	0.225
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.224	Fly
NCOR1	nuclear receptor corepressor 1	0.220
COL4A2	collagen, type IV, alpha 2	0.217	Human
TADA3	transcriptional adaptor 3	0.217
IL1RN	interleukin 1 receptor antagonist	0.213	Human
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.213
RAD21	RAD21 homolog (S. pombe)	0.213
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.212
TGFB1	transforming growth factor, beta 1	0.209
GAS7	growth arrest-specific 7	0.208
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.208
ANXA7	annexin A7	0.207
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.202
MAPK6	mitogen-activated protein kinase 6	0.201
JUN	jun proto-oncogene	0.200
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.200
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.199
TGFBR1	transforming growth factor, beta receptor 1	0.198	Human
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.195	Human
TTN	titin	0.195
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.194
HUWE1	HECT, UBA and WWE domain containing 1	0.193
BMP2	bone morphogenetic protein 2	0.193
CUL5	cullin 5	0.193
FN1	fibronectin 1	0.191	Mouse
BIRC3	baculoviral IAP repeat containing 3	0.191
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.189
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.189	Rat
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.188
ARRDC3	arrestin domain containing 3	0.186
RXRA	retinoid X receptor, alpha	0.185
S100A2	S100 calcium binding protein A2	0.183	Human
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.183
RBBP8	retinoblastoma binding protein 8	0.182
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.181
STAT1	signal transducer and activator of transcription 1, 91kDa	0.180	Mouse
FKBP1A	FK506 binding protein 1A, 12kDa	0.179
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.178
SP100	SP100 nuclear antigen	0.177
LRP6	low density lipoprotein receptor-related protein 6	0.176
S100A1	S100 calcium binding protein A1	0.175	Human
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.175
HP	haptoglobin	0.173
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.173
EPOR	erythropoietin receptor	0.172
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.171
E2F1	E2F transcription factor 1	0.170
SETDB1	SET domain, bifurcated 1	0.170
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.167
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.165
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.163
WIPF1	WAS/WASL interacting protein family, member 1	0.162
SNIP1	Smad nuclear interacting protein 1	0.162
USPL1	ubiquitin specific peptidase like 1	0.161
GCLM	glutamate-cysteine ligase, modifier subunit	0.161
FAM46A	family with sequence similarity 46, member A	0.161
PLCG1	phospholipase C, gamma 1	0.160
COMMD1	copper metabolism (Murr1) domain containing 1	0.159
SYK	spleen tyrosine kinase	0.158
COL4A1	collagen, type IV, alpha 1	0.157	Human
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.153
HSPA4	heat shock 70kDa protein 4	0.153
SOCS3	suppressor of cytokine signaling 3	0.151	Human
CCNE1	cyclin E1	0.150
HIPK2	homeodomain interacting protein kinase 2	0.150
BBS10	Bardet-Biedl syndrome 10	0.150
TUBA1A	tubulin, alpha 1a	0.149
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.146
FEM1B	fem-1 homolog b (C. elegans)	0.146
COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.145
SH3KBP1	SH3-domain kinase binding protein 1	0.145
CAPN7	calpain 7	0.145
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.144	Yeast
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.144
S100A14	S100 calcium binding protein A14	0.143
MAPT	microtubule-associated protein tau	0.141
FGFR3	fibroblast growth factor receptor 3	0.140	Human
SFN	stratifin	0.139
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.139
NID1	nidogen 1	0.139
THBS1	thrombospondin 1	0.138
DAB2IP	DAB2 interacting protein	0.138
BAG1	BCL2-associated athanogene	0.137
ATF5	activating transcription factor 5	0.136
COL4A4	collagen, type IV, alpha 4	0.136	Human
IL1B	interleukin 1, beta	0.135
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.134
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.132
C9orf89	chromosome 9 open reading frame 89	0.132
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.130	Human
SMC6	structural maintenance of chromosomes 6	0.130
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.130
KAT2B	K(lysine) acetyltransferase 2B	0.129
IL1R2	interleukin 1 receptor, type II	0.128
CYR61	cysteine-rich, angiogenic inducer, 61	0.128	Mouse
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.128
NCK1	NCK adaptor protein 1	0.128
SAMD9L	sterile alpha motif domain containing 9-like	0.128
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.128
BIK	BCL2-interacting killer (apoptosis-inducing)	0.128
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.127
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.127
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.126
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.126
RANBP9	RAN binding protein 9	0.126
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.126
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.125
ARIH2	ariadne homolog 2 (Drosophila)	0.125
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.124
ACVR1	activin A receptor, type I	0.124	Human
SMAD9	SMAD family member 9	0.123	Human
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.121
SOX2	SRY (sex determining region Y)-box 2	0.121	Human
EIF1B	eukaryotic translation initiation factor 1B	0.121
TGFB3	transforming growth factor, beta 3	0.119
VDAC2	voltage-dependent anion channel 2	0.119
ARRB2	arrestin, beta 2	0.119
CCND1	cyclin D1	0.118
GDF5	growth differentiation factor 5	0.118	Human
RPL5	ribosomal protein L5	0.117
KRT8	keratin 8	0.117
ACVR1B	activin A receptor, type IB	0.117	Human
UBASH3B	ubiquitin associated and SH3 domain containing B	0.116
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.116
LIN28B	lin-28 homolog B (C. elegans)	0.115
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.114
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.114
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.113
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.113
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.112	Human
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.111
CARD11	caspase recruitment domain family, member 11	0.111
IL1RAP	interleukin 1 receptor accessory protein	0.109
YAP1	Yes-associated protein 1	0.108
PRDM1	PR domain containing 1, with ZNF domain	0.108
FGF10	fibroblast growth factor 10	0.107
MBD1	methyl-CpG binding domain protein 1	0.107
CDK6	cyclin-dependent kinase 6	0.106
CAV2	caveolin 2	0.106
PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	0.106
E2F5	E2F transcription factor 5, p130-binding	0.105
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.105
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.104
LRRK2	leucine-rich repeat kinase 2	0.104	Mouse
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.104
EGLN3	egl nine homolog 3 (C. elegans)	0.103
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.103
MAPK8	mitogen-activated protein kinase 8	0.103
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.103	Human
BBC3	BCL2 binding component 3	0.103
NCF1	neutrophil cytosolic factor 1	0.102
ANXA1	annexin A1	0.102
ENG	endoglin	0.101
AREG	amphiregulin	0.101
UBA2	ubiquitin-like modifier activating enzyme 2	0.101
TGFB2	transforming growth factor, beta 2	0.100
ZFYVE9	zinc finger, FYVE domain containing 9	0.100
BMPR1B	bone morphogenetic protein receptor, type IB	0.100	Human
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.099
JAG1	jagged 1	0.099
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.098
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.098	Human Mouse
SMAD6	SMAD family member 6	0.097	Human
MED28	mediator complex subunit 28	0.097
NBN	nibrin	0.097
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.096
TNK2	tyrosine kinase, non-receptor, 2	0.096
HDAC2	histone deacetylase 2	0.096
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.096
IER3	immediate early response 3	0.095
FKBP4	FK506 binding protein 4, 59kDa	0.095
PTK2	PTK2 protein tyrosine kinase 2	0.095	Mouse
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.095
USP2	ubiquitin specific peptidase 2	0.095	Fly
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.095
ANAPC11	anaphase promoting complex subunit 11	0.094
GOT1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)	0.094
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.094
JAK3	Janus kinase 3	0.093
TRAF6	TNF receptor-associated factor 6	0.093
IFNGR1	interferon gamma receptor 1	0.093
HMOX2	heme oxygenase (decycling) 2	0.093
COL18A1	collagen, type XVIII, alpha 1	0.093
WT1	Wilms tumor 1	0.092
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.092
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.092	Fly
S100A11	S100 calcium binding protein A11	0.091	Human
WEE1	WEE1 homolog (S. pombe)	0.090
COL4A6	collagen, type IV, alpha 6	0.089	Human
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.089
YY1	YY1 transcription factor	0.088
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.087	Yeast
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	0.086
ASB2	ankyrin repeat and SOCS box containing 2	0.086
FNBP1	formin binding protein 1	0.086
BTBD2	BTB (POZ) domain containing 2	0.085
DNM1	dynamin 1	0.084
JAK2	Janus kinase 2	0.083	Mouse
TRIM22	tripartite motif containing 22	0.083
EP300	E1A binding protein p300	0.082
SOX7	SRY (sex determining region Y)-box 7	0.082
IFI35	interferon-induced protein 35	0.082
APP	amyloid beta (A4) precursor protein	0.082	Rat
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.081
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.081
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.081
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.081
IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	0.081
BLNK	B-cell linker	0.081
LAMTOR3	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	0.080
LRDD	leucine-rich repeats and death domain containing	0.080	Mouse
APOC1	apolipoprotein C-I	0.080
EPS15	epidermal growth factor receptor pathway substrate 15	0.080
CSTA	cystatin A (stefin A)	0.079
PTRF	polymerase I and transcript release factor	0.079
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.078
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.077
FYB	FYN binding protein	0.077
FSTL1	follistatin-like 1	0.076
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.076
BCAR1	breast cancer anti-estrogen resistance 1	0.076
NOTCH1	notch 1	0.076
PIM1	pim-1 oncogene	0.075
ATXN3	ataxin 3	0.075
FH	fumarate hydratase	0.075
NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	0.075
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.075
FKBP8	FK506 binding protein 8, 38kDa	0.075
NOTCH3	notch 3	0.075
PTMA	prothymosin, alpha	0.074
E2F4	E2F transcription factor 4, p107/p130-binding	0.074
ADAM12	ADAM metallopeptidase domain 12	0.074
A2M	alpha-2-macroglobulin	0.074
COL4A5	collagen, type IV, alpha 5	0.074	Human
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.074	Yeast
HNF4A	hepatocyte nuclear factor 4, alpha	0.074
EEF1A1	eukaryotic translation elongation factor 1 alpha 1	0.073
TOP1	topoisomerase (DNA) I	0.073
TXN	thioredoxin	0.073
BMPR1A	bone morphogenetic protein receptor, type IA	0.072	Human
NAP1L1	nucleosome assembly protein 1-like 1	0.072
LIMK1	LIM domain kinase 1	0.072
CLU	clusterin	0.071
EGLN1	egl nine homolog 1 (C. elegans)	0.071	Human
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.070
PARP1	poly (ADP-ribose) polymerase 1	0.070
ISG15	ISG15 ubiquitin-like modifier	0.070
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.070
E2F2	E2F transcription factor 2	0.070
TRAF3	TNF receptor-associated factor 3	0.070
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.069
S100A12	S100 calcium binding protein A12	0.069	Human
PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	0.068
PARP4	poly (ADP-ribose) polymerase family, member 4	0.068
GBP1	guanylate binding protein 1, interferon-inducible	0.068
NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit	0.068
LCAT	lecithin-cholesterol acyltransferase	0.068
TIFA	TRAF-interacting protein with forkhead-associated domain	0.067
TNC	tenascin C	0.067
SNCAIP	synuclein, alpha interacting protein	0.067
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.067
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.067
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.067
COL7A1	collagen, type VII, alpha 1	0.067
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.067	Fly
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.067
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.067
KLF5	Kruppel-like factor 5 (intestinal)	0.067
CPE	carboxypeptidase E	0.066
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.066
SMC3	structural maintenance of chromosomes 3	0.066
FZD7	frizzled homolog 7 (Drosophila)	0.066
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.065
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.065
BAK1	BCL2-antagonist/killer 1	0.065
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.065
LTBP2	latent transforming growth factor beta binding protein 2	0.065
BAG2	BCL2-associated athanogene 2	0.064
C20orf24	chromosome 20 open reading frame 24	0.064
ALOX5	arachidonate 5-lipoxygenase	0.064
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.064
MAX	MYC associated factor X	0.063
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.063	Yeast
TRAF4	TNF receptor-associated factor 4	0.063
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.063
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.063
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.063
SSX4	synovial sarcoma, X breakpoint 4	0.062
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.062
MAPK1	mitogen-activated protein kinase 1	0.062
HK2	hexokinase 2	0.062
MEFV	Mediterranean fever	0.062
FES	feline sarcoma oncogene	0.061
PYDC2	pyrin domain containing 2	0.061
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.061
GNL3L	guanine nucleotide binding protein-like 3 (nucleolar)-like	0.061
LGALS3	lectin, galactoside-binding, soluble, 3	0.061
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.061	Human
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.060
TGFA	transforming growth factor, alpha	0.060
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.060
ARNT	aryl hydrocarbon receptor nuclear translocator	0.060
ELK1	ELK1, member of ETS oncogene family	0.059
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.059
PSIP1	PC4 and SFRS1 interacting protein 1	0.059
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.059	Mouse
PDCD6IP	programmed cell death 6 interacting protein	0.059
DIABLO	diablo, IAP-binding mitochondrial protein	0.059
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.059
GBP2	guanylate binding protein 2, interferon-inducible	0.059
NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	0.059
UBQLN4	ubiquilin 4	0.058
MAPK14	mitogen-activated protein kinase 14	0.057
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.057
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.056	Fly
PAIP1	poly(A) binding protein interacting protein 1	0.056
HR	hairless homolog (mouse)	0.056
IFI44	interferon-induced protein 44	0.056
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.056
MYOD1	myogenic differentiation 1	0.056
FUNDC2	FUN14 domain containing 2	0.056
ZRANB1	zinc finger, RAN-binding domain containing 1	0.056
PRKG1	protein kinase, cGMP-dependent, type I	0.056
HDAC3	histone deacetylase 3	0.056
PI3	peptidase inhibitor 3, skin-derived	0.055
SORBS3	sorbin and SH3 domain containing 3	0.055
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.055
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.055
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.055
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.055
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.055
CLTC	clathrin, heavy chain (Hc)	0.055
SOX9	SRY (sex determining region Y)-box 9	0.054	Human
FKBP3	FK506 binding protein 3, 25kDa	0.054
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.054
VIM	vimentin	0.054
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.054
SKP2	S-phase kinase-associated protein 2 (p45)	0.054
CHCHD3	coiled-coil-helix-coiled-coil-helix domain containing 3	0.054
HSPA1B	heat shock 70kDa protein 1B	0.054
TM4SF1	transmembrane 4 L six family member 1	0.054
NDUFB10	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa	0.053
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.053
AIG1	androgen-induced 1	0.053
ADRBK1	adrenergic, beta, receptor kinase 1	0.053
FOXF1	forkhead box F1	0.053
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.053
FZD8	frizzled homolog 8 (Drosophila)	0.053
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.053
FOXF2	forkhead box F2	0.052
PTTG1	pituitary tumor-transforming 1	0.052
HSF1	heat shock transcription factor 1	0.052
MARCKSL1	MARCKS-like 1	0.052
CYFIP2	cytoplasmic FMR1 interacting protein 2	0.052
TP53BP2	tumor protein p53 binding protein, 2	0.052
ANXA4	annexin A4	0.051
UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked	0.051
ZHX1	zinc fingers and homeoboxes 1	0.051
POLH	polymerase (DNA directed), eta	0.051
TMX2	thioredoxin-related transmembrane protein 2	0.050
WDR5	WD repeat domain 5	0.050
ARHGAP5	Rho GTPase activating protein 5	0.050
AHNAK	AHNAK nucleoprotein	0.050
PELP1	proline, glutamate and leucine rich protein 1	0.050
ZNF746	zinc finger protein 746	0.050
PTPRF	protein tyrosine phosphatase, receptor type, F	0.050
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.050
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.050	Human
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.050
TP73	tumor protein p73	0.050
GRSF1	G-rich RNA sequence binding factor 1	0.050
MCAM	melanoma cell adhesion molecule	0.050
MATR3	matrin 3	0.049
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.049
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.049
LRP1	low density lipoprotein receptor-related protein 1	0.049
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.049
SPDEF	SAM pointed domain containing ets transcription factor	0.049
CLSPN	claspin	0.049
EPHA2	EPH receptor A2	0.049
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.049
HSPE1	heat shock 10kDa protein 1 (chaperonin 10)	0.049
NOV	nephroblastoma overexpressed gene	0.048
CALD1	caldesmon 1	0.048
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.048
ZNRF1	zinc and ring finger 1	0.048
NOG	noggin	0.048
BST2	bone marrow stromal cell antigen 2	0.048
BMP7	bone morphogenetic protein 7	0.048	Human
TDGF1	teratocarcinoma-derived growth factor 1	0.048
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.048
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.048
NCOR2	nuclear receptor corepressor 2	0.048
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.048
ANKRD28	ankyrin repeat domain 28	0.048
LCK	lymphocyte-specific protein tyrosine kinase	0.048
HOXD1	homeobox D1	0.048
SOX10	SRY (sex determining region Y)-box 10	0.048	Human
SNW1	SNW domain containing 1	0.047
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.047
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.047
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.047
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.047
MEMO1	mediator of cell motility 1	0.047
EMP1	epithelial membrane protein 1	0.047
DDB1	damage-specific DNA binding protein 1, 127kDa	0.047
C11orf58	chromosome 11 open reading frame 58	0.047
ZNF512B	zinc finger protein 512B	0.046
AURKB	aurora kinase B	0.046
PDCD4	programmed cell death 4 (neoplastic transformation inhibitor)	0.046
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.046
ARHGAP25	Rho GTPase activating protein 25	0.046
KALRN	kalirin, RhoGEF kinase	0.046
SOX13	SRY (sex determining region Y)-box 13	0.046
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.046
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.046
IGFBP3	insulin-like growth factor binding protein 3	0.046
CCL4	chemokine (C-C motif) ligand 4	0.046
SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	0.046
IFIT3	interferon-induced protein with tetratricopeptide repeats 3	0.046
NRP1	neuropilin 1	0.046
EREG	epiregulin	0.046
CBX5	chromobox homolog 5	0.046
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.045
UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1	0.045
TTC35	tetratricopeptide repeat domain 35	0.045
PTPRE	protein tyrosine phosphatase, receptor type, E	0.045
INHBB	inhibin, beta B	0.045
EDF1	endothelial differentiation-related factor 1	0.045
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.045
PDCD2	programmed cell death 2	0.045
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.045
OSMR	oncostatin M receptor	0.045
RND3	Rho family GTPase 3	0.045
AGER	advanced glycosylation end product-specific receptor	0.045
PXDN	peroxidasin homolog (Drosophila)	0.045
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.044
ZFYVE1	zinc finger, FYVE domain containing 1	0.044
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.044
CUL4A	cullin 4A	0.044
PINK1	PTEN induced putative kinase 1	0.044
RNF144B	ring finger protein 144B	0.044
AQP9	aquaporin 9	0.044
RYBP	RING1 and YY1 binding protein	0.044
ERH	enhancer of rudimentary homolog (Drosophila)	0.044
SFRP1	secreted frizzled-related protein 1	0.044
FGF7	fibroblast growth factor 7	0.044
MEOX2	mesenchyme homeobox 2	0.044
ZFAND5	zinc finger, AN1-type domain 5	0.044
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.044
MATK	megakaryocyte-associated tyrosine kinase	0.044
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.044
NRG1	neuregulin 1	0.044
GRB7	growth factor receptor-bound protein 7	0.044
ENDOG	endonuclease G	0.043
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.043
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.043
SIRT2	sirtuin 2	0.043
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.043
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.043
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.043
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.043
FANCD2	Fanconi anemia, complementation group D2	0.043
TIMP3	TIMP metallopeptidase inhibitor 3	0.043
FAF2	Fas associated factor family member 2	0.043
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.043
SRI	sorcin	0.043
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.043
GSN	gelsolin	0.042
PPID	peptidylprolyl isomerase D	0.042
SOX5	SRY (sex determining region Y)-box 5	0.042
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.042
PLAT	plasminogen activator, tissue	0.042
NUCB2	nucleobindin 2	0.042
HIST2H3C	histone cluster 2, H3c	0.042
HMGA2	high mobility group AT-hook 2	0.042
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.042
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.042
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.042
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.042
FGF2	fibroblast growth factor 2 (basic)	0.042
KIAA1967	KIAA1967	0.042
ADRM1	adhesion regulating molecule 1	0.042
CKAP5	cytoskeleton associated protein 5	0.042
MEN1	multiple endocrine neoplasia I	0.042	Mouse
BCL2A1	BCL2-related protein A1	0.041	Human
TEX10	testis expressed 10	0.041
PDCD10	programmed cell death 10	0.041
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.041
GOT2	glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)	0.041
SRCIN1	SRC kinase signaling inhibitor 1	0.041
PPARA	peroxisome proliferator-activated receptor alpha	0.041	Human
APOA2	apolipoprotein A-II	0.041
CDCA3	cell division cycle associated 3	0.041
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.041
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.041
PDGFA	platelet-derived growth factor alpha polypeptide	0.041
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.041
SNAI1	snail homolog 1 (Drosophila)	0.041
AKAP12	A kinase (PRKA) anchor protein 12	0.041
CDK1	cyclin-dependent kinase 1	0.041
CFP	complement factor properdin	0.041
COL16A1	collagen, type XVI, alpha 1	0.041
SIGLEC7	sialic acid binding Ig-like lectin 7	0.041
COL2A1	collagen, type II, alpha 1	0.041
MLF2	myeloid leukemia factor 2	0.041
KIAA1712	KIAA1712	0.040
HMGN2	high mobility group nucleosomal binding domain 2	0.040
CENPF	centromere protein F, 350/400kDa (mitosin)	0.040
NDFIP2	Nedd4 family interacting protein 2	0.040
TYROBP	TYRO protein tyrosine kinase binding protein	0.040
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.040	Rat
TANK	TRAF family member-associated NFKB activator	0.040
EIF4A2	eukaryotic translation initiation factor 4A2	0.040
UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	0.040
MARCH5	membrane-associated ring finger (C3HC4) 5	0.040
SIAH1	seven in absentia homolog 1 (Drosophila)	0.040
EFNB3	ephrin-B3	0.040
BCL2L2	BCL2-like 2	0.040	Human
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.040
TIMP2	TIMP metallopeptidase inhibitor 2	0.040
CST7	cystatin F (leukocystatin)	0.040
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.040
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.040
RPS27A	ribosomal protein S27a	0.040
CCNB2	cyclin B2	0.039
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.039
SMC1A	structural maintenance of chromosomes 1A	0.039
RNF10	ring finger protein 10	0.039
NCK2	NCK adaptor protein 2	0.039
FPR1	formyl peptide receptor 1	0.039
NRP2	neuropilin 2	0.039
FOXM1	forkhead box M1	0.039
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.039
ONECUT1	one cut homeobox 1	0.039
HDAC4	histone deacetylase 4	0.039
TREM1	triggering receptor expressed on myeloid cells 1	0.039
SHANK2	SH3 and multiple ankyrin repeat domains 2	0.039
EIF3K	eukaryotic translation initiation factor 3, subunit K	0.039
RRM2B	ribonucleotide reductase M2 B (TP53 inducible)	0.039
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.038
CCNB1	cyclin B1	0.038
LAP3	leucine aminopeptidase 3	0.038
BABAM1	BRISC and BRCA1 A complex member 1	0.038
FOXG1	forkhead box G1	0.038	Human
NCF2	neutrophil cytosolic factor 2	0.038
BECN1	beclin 1, autophagy related	0.038
RHOJ	ras homolog gene family, member J	0.038
UBL4A	ubiquitin-like 4A	0.038
F2R	coagulation factor II (thrombin) receptor	0.038
SH3PXD2A	SH3 and PX domains 2A	0.038
PRKCDBP	protein kinase C, delta binding protein	0.038
OBFC2A	oligonucleotide/oligosaccharide-binding fold containing 2A	0.038
APLP1	amyloid beta (A4) precursor-like protein 1	0.038
DUSP6	dual specificity phosphatase 6	0.038
TNS3	tensin 3	0.038
RNF5	ring finger protein 5	0.038
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.038
TPT1	tumor protein, translationally-controlled 1	0.038
TRIM5	tripartite motif containing 5	0.038
IFI16	interferon, gamma-inducible protein 16	0.038
TACSTD2	tumor-associated calcium signal transducer 2	0.037
DDB2	damage-specific DNA binding protein 2, 48kDa	0.037
IFI44L	interferon-induced protein 44-like	0.037
TBX2	T-box 2	0.037
IGF1R	insulin-like growth factor 1 receptor	0.037
BRMS1	breast cancer metastasis suppressor 1	0.037
ETF1	eukaryotic translation termination factor 1	0.037
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.037
CCNA2	cyclin A2	0.037
IFIT5	interferon-induced protein with tetratricopeptide repeats 5	0.037
UBE3A	ubiquitin protein ligase E3A	0.037	Fly
NPY2R	neuropeptide Y receptor Y2	0.037
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.037
CYBA	cytochrome b-245, alpha polypeptide	0.037
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.037
TNS4	tensin 4	0.037
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.037	Human
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.036
IRAK1	interleukin-1 receptor-associated kinase 1	0.036
MYO6	myosin VI	0.036
UBE2F	ubiquitin-conjugating enzyme E2F (putative)	0.036
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.036
COL5A2	collagen, type V, alpha 2	0.036
RAB27A	RAB27A, member RAS oncogene family	0.036
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.036