Process View
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "mapk cascade"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
EGFR | epidermal growth factor receptor | 1.000 | ||
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 1.000 | Human | |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 1.000 | Fly | |
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 1.000 | ||
SMAD2 | SMAD family member 2 | 1.000 | ||
SMN1 | survival of motor neuron 1, telomeric | 1.000 | ||
MAPK1 | mitogen-activated protein kinase 1 | 0.999 | ||
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.999 | ||
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.999 | Fly | |
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.999 | Rat | |
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.999 | Fly | |
YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.998 | Fly | |
SH3KBP1 | SH3-domain kinase binding protein 1 | 0.998 | ||
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.997 | ||
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.996 | Fly | |
MAPK14 | mitogen-activated protein kinase 14 | 0.996 | ||
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.994 | Fly | |
ILK | integrin-linked kinase | 0.992 | Rat | |
IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.990 | Human Mouse Rat | |
MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.990 | ||
SMAD3 | SMAD family member 3 | 0.988 | ||
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.988 | ||
GRB2 | growth factor receptor-bound protein 2 | 0.988 | Mouse Fly | |
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.988 | Mouse Rat | |
FYN | FYN oncogene related to SRC, FGR, YES | 0.988 | ||
FGFR2 | fibroblast growth factor receptor 2 | 0.987 | ||
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.987 | Mouse | |
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.985 | ||
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.985 | Mouse Rat | |
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.984 | ||
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.984 | Human Rat Fly | |
CSNK1E | casein kinase 1, epsilon | 0.983 | ||
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.981 | ||
ESR1 | estrogen receptor 1 | 0.981 | Rat | |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.979 | ||
PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.979 | Human Mouse | |
IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.974 | Human | |
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.972 | ||
SFN | stratifin | 0.972 | Fly | |
JUN | jun proto-oncogene | 0.970 | Fly | |
DUSP1 | dual specificity phosphatase 1 | 0.963 | ||
FLNA | filamin A, alpha | 0.959 | ||
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.959 | ||
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.957 | ||
NCOA3 | nuclear receptor coactivator 3 | 0.957 | ||
SMAD7 | SMAD family member 7 | 0.956 | ||
GSK3B | glycogen synthase kinase 3 beta | 0.954 | Rat Fly | |
TRAF6 | TNF receptor-associated factor 6 | 0.949 | ||
TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.946 | ||
HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 0.943 | ||
BIRC3 | baculoviral IAP repeat containing 3 | 0.939 | ||
FN1 | fibronectin 1 | 0.938 | ||
TRAF3 | TNF receptor-associated factor 3 | 0.937 | Human | |
FGFR1 | fibroblast growth factor receptor 1 | 0.937 | ||
GAB1 | GRB2-associated binding protein 1 | 0.935 | Mouse | |
ENG | endoglin | 0.933 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.932 | ||
LAT | linker for activation of T cells | 0.931 | ||
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.924 | ||
C1QA | complement component 1, q subcomponent, A chain | 0.920 | Human | |
KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.919 | ||
MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.918 | ||
CCR5 | chemokine (C-C motif) receptor 5 | 0.916 | ||
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.908 | Fly | |
MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.906 | Human Mouse | |
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.904 | ||
LRRK2 | leucine-rich repeat kinase 2 | 0.904 | ||
TGFB1 | transforming growth factor, beta 1 | 0.901 | ||
VEGFA | vascular endothelial growth factor A | 0.898 | ||
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.896 | Rat | |
XIAP | X-linked inhibitor of apoptosis | 0.893 | ||
SRPK2 | SRSF protein kinase 2 | 0.886 | ||
MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.884 | Human Zebrafish Mouse Rat Worm Fly | |
ZNF43 | zinc finger protein 43 | 0.882 | ||
IL6 | interleukin 6 (interferon, beta 2) | 0.876 | ||
SOCS3 | suppressor of cytokine signaling 3 | 0.870 | ||
TEK | TEK tyrosine kinase, endothelial | 0.868 | ||
MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.868 | ||
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.866 | Yeast Mouse | |
MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.864 | Mouse | |
GHR | growth hormone receptor | 0.861 | Rat | |
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.856 | Human | |
IGF1R | insulin-like growth factor 1 receptor | 0.851 | ||
PTEN | phosphatase and tensin homolog | 0.848 | ||
FHL2 | four and a half LIM domains 2 | 0.848 | ||
PTK2 | PTK2 protein tyrosine kinase 2 | 0.845 | Human Rat Fly | |
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.842 | ||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.841 | ||
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.840 | ||
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.833 | ||
PRKCA | protein kinase C, alpha | 0.832 | Mouse | |
BCR | breakpoint cluster region | 0.825 | ||
IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.819 | ||
LCK | lymphocyte-specific protein tyrosine kinase | 0.819 | ||
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.816 | ||
MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.814 | ||
SIRT1 | sirtuin 1 | 0.810 | ||
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.806 | Rat | |
PKM2 | pyruvate kinase, muscle | 0.802 | ||
BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.792 | ||
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.791 | ||
SMAD4 | SMAD family member 4 | 0.776 | ||
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.775 | Human Rat | |
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.772 | Human Rat | |
AXIN1 | axin 1 | 0.769 | Zebrafish Mouse | |
ARRB2 | arrestin, beta 2 | 0.767 | ||
FLNB | filamin B, beta | 0.763 | ||
WASL | Wiskott-Aldrich syndrome-like | 0.760 | ||
FAS | Fas (TNF receptor superfamily, member 6) | 0.759 | ||
VAV1 | vav 1 guanine nucleotide exchange factor | 0.752 | ||
MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.751 | Mouse Rat | |
DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.747 | ||
DLG1 | discs, large homolog 1 (Drosophila) | 0.744 | ||
TXN | thioredoxin | 0.742 | ||
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.723 | Mouse | |
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.700 | ||
ZNF746 | zinc finger protein 746 | 0.690 | ||
TRAF5 | TNF receptor-associated factor 5 | 0.687 | Human | |
CCL2 | chemokine (C-C motif) ligand 2 | 0.685 | ||
MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.678 | Mouse Rat | |
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.674 | ||
ERBB2IP | erbb2 interacting protein | 0.673 | ||
IL8 | interleukin 8 | 0.666 | ||
A2M | alpha-2-macroglobulin | 0.661 | ||
CCNE1 | cyclin E1 | 0.651 | ||
FGF1 | fibroblast growth factor 1 (acidic) | 0.648 | Human | |
CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.639 | ||
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.632 | ||
NRP1 | neuropilin 1 | 0.632 | Mouse | |
STK4 | serine/threonine kinase 4 | 0.632 | ||
HSPB1 | heat shock 27kDa protein 1 | 0.630 | ||
NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.629 | ||
PSG9 | pregnancy specific beta-1-glycoprotein 9 | 0.625 | Rat | |
NCK1 | NCK adaptor protein 1 | 0.617 | ||
MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) | 0.611 | Fly | |
PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.603 | ||
BMPR1A | bone morphogenetic protein receptor, type IA | 0.603 | Human | |
IL1B | interleukin 1, beta | 0.588 | ||
HDAC4 | histone deacetylase 4 | 0.588 | ||
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.588 | ||
MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.587 | Human Mouse Rat Fly | |
ATF3 | activating transcription factor 3 | 0.579 | ||
TTR | transthyretin | 0.578 | ||
CD2 | CD2 molecule | 0.575 | ||
CREB1 | cAMP responsive element binding protein 1 | 0.575 | ||
TRAF1 | TNF receptor-associated factor 1 | 0.574 | Human | |
PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.572 | ||
ZNF675 | zinc finger protein 675 | 0.566 | ||
SH3RF1 | SH3 domain containing ring finger 1 | 0.562 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.561 | ||
PECAM1 | platelet/endothelial cell adhesion molecule | 0.553 | ||
PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.548 | ||
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.546 | ||
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.544 | Mouse | |
ADORA2A | adenosine A2a receptor | 0.540 | ||
ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.539 | Human Rat Fly | |
LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.537 | ||
ZFP36L1 | zinc finger protein 36, C3H type-like 1 | 0.534 | ||
CYTH4 | cytohesin 4 | 0.531 | Fly | |
RXRA | retinoid X receptor, alpha | 0.528 | ||
CTTNBP2NL | CTTNBP2 N-terminal like | 0.525 | ||
MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.523 | Human Mouse Rat Worm | |
ZNF253 | zinc finger protein 253 | 0.523 | ||
CTGF | connective tissue growth factor | 0.522 | ||
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.514 | Human | |
ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.513 | ||
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.511 | ||
MAPK3 | mitogen-activated protein kinase 3 | 0.510 | ||
TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.503 | Human | |
LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.499 | ||
PML | promyelocytic leukemia | 0.499 | ||
DAXX | death-domain associated protein | 0.496 | ||
JAK2 | Janus kinase 2 | 0.493 | Rat | |
KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog | 0.488 | ||
BBS10 | Bardet-Biedl syndrome 10 | 0.480 | ||
MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.479 | Human Mouse Worm | |
STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.478 | ||
RASSF5 | Ras association (RalGDS/AF-6) domain family member 5 | 0.475 | ||
NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.475 | ||
CCR7 | chemokine (C-C motif) receptor 7 | 0.474 | Human | |
DUSP5 | dual specificity phosphatase 5 | 0.474 | Human Rat | |
SLA | Src-like-adaptor | 0.468 | ||
THBS1 | thrombospondin 1 | 0.464 | ||
BMP2 | bone morphogenetic protein 2 | 0.463 | ||
IER2 | immediate early response 2 | 0.459 | ||
HNRNPH2 | heterogeneous nuclear ribonucleoprotein H2 (H') | 0.459 | ||
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.458 | ||
MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.456 | ||
TNF | tumor necrosis factor | 0.455 | ||
MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.454 | ||
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.453 | ||
BCL10 | B-cell CLL/lymphoma 10 | 0.448 | ||
PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) | 0.448 | ||
TRAF2 | TNF receptor-associated factor 2 | 0.447 | ||
MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.446 | ||
IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.446 | ||
C1QC | complement component 1, q subcomponent, C chain | 0.444 | Human | |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.444 | ||
ZNF273 | zinc finger protein 273 | 0.443 | Human | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.442 | ||
ABI1 | abl-interactor 1 | 0.442 | ||
TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.442 | ||
HTR4 | 5-hydroxytryptamine (serotonin) receptor 4 | 0.441 | Human | |
UTRN | utrophin | 0.439 | ||
SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.439 | ||
YAP1 | Yes-associated protein 1 | 0.438 | ||
GUCY2C | guanylate cyclase 2C (heat stable enterotoxin receptor) | 0.437 | ||
LAMP1 | lysosomal-associated membrane protein 1 | 0.435 | ||
LRP6 | low density lipoprotein receptor-related protein 6 | 0.434 | Human | |
ARRB1 | arrestin, beta 1 | 0.434 | ||
PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.434 | ||
IL1R1 | interleukin 1 receptor, type I | 0.426 | ||
UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.425 | ||
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.424 | ||
CUL1 | cullin 1 | 0.423 | ||
NCAM1 | neural cell adhesion molecule 1 | 0.423 | ||
ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.423 | ||
DUSP6 | dual specificity phosphatase 6 | 0.421 | ||
RFWD2 | ring finger and WD repeat domain 2 | 0.420 | ||
TGFB2 | transforming growth factor, beta 2 | 0.415 | ||
EGR2 | early growth response 2 | 0.414 | ||
MED28 | mediator complex subunit 28 | 0.411 | ||
EGR1 | early growth response 1 | 0.411 | Worm | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.407 | Human | |
TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.406 | ||
APOA1 | apolipoprotein A-I | 0.405 | Human | |
CCKBR | cholecystokinin B receptor | 0.405 | Rat | |
TLN1 | talin 1 | 0.405 | ||
RAP1A | RAP1A, member of RAS oncogene family | 0.400 | Human Mouse Rat | |
TGFB3 | transforming growth factor, beta 3 | 0.397 | Rat | |
ITGAV | integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) | 0.397 | Mouse | |
RNF11 | ring finger protein 11 | 0.397 | ||
TGFA | transforming growth factor, alpha | 0.396 | ||
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.395 | Fly | |
SPRY4 | sprouty homolog 4 (Drosophila) | 0.395 | Human Mouse | |
CCL22 | chemokine (C-C motif) ligand 22 | 0.392 | Human | |
IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.392 | ||
CCL5 | chemokine (C-C motif) ligand 5 | 0.392 | ||
PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.389 | ||
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.389 | Mouse Rat | |
SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.387 | ||
FKBP1A | FK506 binding protein 1A, 12kDa | 0.387 | ||
KLF6 | Kruppel-like factor 6 | 0.387 | ||
PLCG1 | phospholipase C, gamma 1 | 0.386 | Human | |
APP | amyloid beta (A4) precursor protein | 0.384 | ||
PEA15 | phosphoprotein enriched in astrocytes 15 | 0.380 | ||
TFF1 | trefoil factor 1 | 0.378 | ||
EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.375 | Fly | |
CCL7 | chemokine (C-C motif) ligand 7 | 0.375 | Human | |
MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.374 | Mouse | |
RALGDS | ral guanine nucleotide dissociation stimulator | 0.373 | ||
HCK | hemopoietic cell kinase | 0.368 | ||
BTK | Bruton agammaglobulinemia tyrosine kinase | 0.366 | ||
ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.365 | ||
SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.363 | ||
PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.363 | Human Fly | |
CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.361 | ||
PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.360 | ||
FZD1 | frizzled homolog 1 (Drosophila) | 0.358 | Human | |
APOE | apolipoprotein E | 0.358 | ||
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.357 | ||
IGF2 | insulin-like growth factor 2 (somatomedin A) | 0.357 | ||
SNIP1 | Smad nuclear interacting protein 1 | 0.356 | ||
MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.356 | ||
USP15 | ubiquitin specific peptidase 15 | 0.356 | ||
PPP6C | protein phosphatase 6, catalytic subunit | 0.355 | ||
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.350 | ||
FGF7 | fibroblast growth factor 7 | 0.349 | Human | |
CD93 | CD93 molecule | 0.346 | ||
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.346 | ||
TSC22D1 | TSC22 domain family, member 1 | 0.344 | ||
NCOA1 | nuclear receptor coactivator 1 | 0.341 | ||
SMAD1 | SMAD family member 1 | 0.339 | Mouse Rat | |
CCR1 | chemokine (C-C motif) receptor 1 | 0.338 | ||
FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.337 | ||
SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.333 | ||
ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.332 | ||
GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 | 0.332 | ||
FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.332 | ||
NCK2 | NCK adaptor protein 2 | 0.331 | ||
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.330 | ||
PRDX1 | peroxiredoxin 1 | 0.330 | Mouse | |
MAP3K11 | mitogen-activated protein kinase kinase kinase 11 | 0.328 | ||
MAPK11 | mitogen-activated protein kinase 11 | 0.326 | ||
CAV2 | caveolin 2 | 0.325 | ||
PICK1 | protein interacting with PRKCA 1 | 0.321 | ||
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.320 | Fly | |
ZNF708 | zinc finger protein 708 | 0.317 | Human | |
BAG3 | BCL2-associated athanogene 3 | 0.317 | ||
PSG5 | pregnancy specific beta-1-glycoprotein 5 | 0.316 | Rat | |
WT1 | Wilms tumor 1 | 0.314 | ||
PTPRR | protein tyrosine phosphatase, receptor type, R | 0.314 | ||
TGFBR1 | transforming growth factor, beta receptor 1 | 0.314 | ||
ACACA | acetyl-CoA carboxylase alpha | 0.309 | ||
IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.309 | ||
MLL | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila) | 0.307 | ||
MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.307 | ||
PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.306 | ||
NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.305 | ||
IER3 | immediate early response 3 | 0.305 | ||
S100B | S100 calcium binding protein B | 0.304 | ||
ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.301 | Mouse | |
SCHIP1 | schwannomin interacting protein 1 | 0.299 | ||
CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.299 | Rat | |
RANBP2 | RAN binding protein 2 | 0.298 | ||
CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.295 | ||
FGA | fibrinogen alpha chain | 0.294 | ||
FGFR3 | fibroblast growth factor receptor 3 | 0.293 | ||
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.292 | ||
CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.292 | Fly | |
PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.291 | ||
DUSP7 | dual specificity phosphatase 7 | 0.290 | ||
MYO1C | myosin IC | 0.290 | ||
CSF1R | colony stimulating factor 1 receptor | 0.289 | Human Mouse Fly | |
NCOR1 | nuclear receptor corepressor 1 | 0.288 | ||
RAMP2 | receptor (G protein-coupled) activity modifying protein 2 | 0.287 | ||
FGB | fibrinogen beta chain | 0.287 | ||
PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.287 | ||
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.287 | ||
PTPRB | protein tyrosine phosphatase, receptor type, B | 0.286 | Human | |
BMPR1B | bone morphogenetic protein receptor, type IB | 0.285 | Human | |
EGR3 | early growth response 3 | 0.284 | Worm | |
DCN | decorin | 0.283 | ||
SFRP1 | secreted frizzled-related protein 1 | 0.280 | Mouse | |
ZNF93 | zinc finger protein 93 | 0.278 | ||
FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.277 | ||
CCL4 | chemokine (C-C motif) ligand 4 | 0.275 | Human | |
PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.274 | ||
TLR2 | toll-like receptor 2 | 0.273 | ||
ITGA6 | integrin, alpha 6 | 0.273 | ||
MPDZ | multiple PDZ domain protein | 0.270 | ||
NCOA2 | nuclear receptor coactivator 2 | 0.270 | ||
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.266 | ||
RET | ret proto-oncogene | 0.266 | Mouse | |
LRRC7 | leucine rich repeat containing 7 | 0.265 | ||
PDCD6IP | programmed cell death 6 interacting protein | 0.265 | ||
TNPO1 | transportin 1 | 0.265 | ||
CCL3 | chemokine (C-C motif) ligand 3 | 0.264 | ||
BMP4 | bone morphogenetic protein 4 | 0.264 | ||
SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.263 | ||
MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.263 | Human Fly | |
MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.263 | ||
FOXD3 | forkhead box D3 | 0.262 | ||
BAG1 | BCL2-associated athanogene | 0.262 | ||
SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.262 | Human | |
PLAU | plasminogen activator, urokinase | 0.262 | ||
PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.261 | Human Yeast | |
PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 0.260 | ||
CSK | c-src tyrosine kinase | 0.260 | Rat | |
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.260 | ||
IRF4 | interferon regulatory factor 4 | 0.259 | ||
ZNF85 | zinc finger protein 85 | 0.258 | Human | |
SYK | spleen tyrosine kinase | 0.258 | Mouse Fly | |
GDF5 | growth differentiation factor 5 | 0.257 | Human | |
JAG1 | jagged 1 | 0.257 | ||
CHERP | calcium homeostasis endoplasmic reticulum protein | 0.256 | ||
CD63 | CD63 molecule | 0.256 | ||
TRAF3IP3 | TRAF3 interacting protein 3 | 0.256 | ||
MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.255 | ||
PRPF38A | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A | 0.255 | ||
NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.255 | ||
TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.254 | Human | |
MYD88 | myeloid differentiation primary response gene (88) | 0.252 | Mouse Rat | |
DLG4 | discs, large homolog 4 (Drosophila) | 0.251 | ||
ETS2 | v-ets erythroblastosis virus E26 oncogene homolog 2 (avian) | 0.251 | ||
EPHA2 | EPH receptor A2 | 0.251 | ||
CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.249 | Human | |
NLRC4 | NLR family, CARD domain containing 4 | 0.247 | ||
SKIL | SKI-like oncogene | 0.247 | ||
BIRC2 | baculoviral IAP repeat containing 2 | 0.247 | ||
ABI2 | abl-interactor 2 | 0.246 | ||
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.245 | ||
KCNA1 | potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) | 0.245 | ||
CD28 | CD28 molecule | 0.244 | ||
CCL8 | chemokine (C-C motif) ligand 8 | 0.243 | Human | |
EDN1 | endothelin 1 | 0.243 | ||
FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.242 | ||
COL1A1 | collagen, type I, alpha 1 | 0.241 | ||
FGF4 | fibroblast growth factor 4 | 0.241 | ||
ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta | 0.241 | ||
SOX10 | SRY (sex determining region Y)-box 10 | 0.240 | Human | |
MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.239 | ||
LTK | leukocyte receptor tyrosine kinase | 0.239 | Human Fly | |
SASH3 | SAM and SH3 domain containing 3 | 0.239 | Human | |
HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.239 | ||
SORBS1 | sorbin and SH3 domain containing 1 | 0.239 | ||
GBP3 | guanylate binding protein 3 | 0.237 | ||
CD247 | CD247 molecule | 0.235 | ||
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.234 | ||
CD81 | CD81 molecule | 0.233 | ||
HSPB2 | heat shock 27kDa protein 2 | 0.233 | ||
CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.232 | Human | |
KIF5B | kinesin family member 5B | 0.232 | ||
CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.231 | ||
IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.230 | ||
RASA1 | RAS p21 protein activator (GTPase activating protein) 1 | 0.230 | ||
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.230 | ||
PTAFR | platelet-activating factor receptor | 0.229 | Human | |
MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.229 | ||
RPAP3 | RNA polymerase II associated protein 3 | 0.228 | ||
NCF2 | neutrophil cytosolic factor 2 | 0.228 | ||
PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) | 0.228 | ||
TBX2 | T-box 2 | 0.226 | ||
TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.225 | ||
PSG1 | pregnancy specific beta-1-glycoprotein 1 | 0.224 | ||
RHOU | ras homolog gene family, member U | 0.224 | ||
MYO10 | myosin X | 0.223 | ||
RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.222 | ||
HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.222 | Mouse | |
FGG | fibrinogen gamma chain | 0.222 | ||
DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.221 | Human | |
SOX2 | SRY (sex determining region Y)-box 2 | 0.221 | ||
HP | haptoglobin | 0.221 | ||
TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.221 | ||
ZMYND11 | zinc finger, MYND-type containing 11 | 0.220 | ||
STK3 | serine/threonine kinase 3 | 0.219 | Mouse | |
CD40LG | CD40 ligand | 0.219 | ||
IGFBP5 | insulin-like growth factor binding protein 5 | 0.218 | ||
SH3GL3 | SH3-domain GRB2-like 3 | 0.217 | ||
EPRS | glutamyl-prolyl-tRNA synthetase | 0.217 | ||
IFNG | interferon, gamma | 0.217 | ||
ARHGAP9 | Rho GTPase activating protein 9 | 0.217 | ||
SOS1 | son of sevenless homolog 1 (Drosophila) | 0.216 | ||
CBLC | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | 0.215 | ||
GRB10 | growth factor receptor-bound protein 10 | 0.215 | ||
SH3GL2 | SH3-domain GRB2-like 2 | 0.215 | ||
FGF2 | fibroblast growth factor 2 (basic) | 0.214 | ||
NGF | nerve growth factor (beta polypeptide) | 0.214 | Human | |
PAX8 | paired box 8 | 0.214 | ||
KPNB1 | karyopherin (importin) beta 1 | 0.213 | ||
SQSTM1 | sequestosome 1 | 0.213 | ||
U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.213 | ||
IL21R | interleukin 21 receptor | 0.213 | ||
DUSP3 | dual specificity phosphatase 3 | 0.212 | ||
WNT3A | wingless-type MMTV integration site family, member 3A | 0.212 | Human | |
WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.211 | ||
LDLR | low density lipoprotein receptor | 0.211 | ||
IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.211 | ||
WNT1 | wingless-type MMTV integration site family, member 1 | 0.209 | Human | |
ARF6 | ADP-ribosylation factor 6 | 0.209 | ||
MUC1 | mucin 1, cell surface associated | 0.209 | ||
SORBS2 | sorbin and SH3 domain containing 2 | 0.209 | ||
RIN1 | Ras and Rab interactor 1 | 0.208 | ||
INHBA | inhibin, beta A | 0.208 | ||
MOBKL3 | MOB1, Mps One Binder kinase activator-like 3 (yeast) | 0.208 | ||
UBE3A | ubiquitin protein ligase E3A | 0.207 | ||
ACVR1 | activin A receptor, type I | 0.206 | Human | |
BTRC | beta-transducin repeat containing | 0.206 | ||
CCL11 | chemokine (C-C motif) ligand 11 | 0.205 | Human | |
ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.205 | ||
EPHB3 | EPH receptor B3 | 0.204 | Human | |
CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.204 | ||
C1S | complement component 1, s subcomponent | 0.204 | ||
ZFAND5 | zinc finger, AN1-type domain 5 | 0.203 | ||
FOXC2 | forkhead box C2 (MFH-1, mesenchyme forkhead 1) | 0.202 | ||
ITGB7 | integrin, beta 7 | 0.202 | ||
CD9 | CD9 molecule | 0.201 | Human | |
NRP2 | neuropilin 2 | 0.201 | ||
CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.200 | Human | |
CTSA | cathepsin A | 0.199 | ||
DARC | Duffy blood group, chemokine receptor | 0.198 | ||
CD68 | CD68 molecule | 0.198 | ||
FOXN1 | forkhead box N1 | 0.197 | ||
SLAMF7 | SLAM family member 7 | 0.196 | ||
NTF3 | neurotrophin 3 | 0.196 | ||
GAB2 | GRB2-associated binding protein 2 | 0.196 | ||
MAPT | microtubule-associated protein tau | 0.196 | ||
MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.195 | ||
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.194 | ||
SOS2 | son of sevenless homolog 2 (Drosophila) | 0.193 | ||
PSG6 | pregnancy specific beta-1-glycoprotein 6 | 0.193 | Rat | |
EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.193 | Fly | |
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.191 | ||
ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.191 | ||
ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.191 | ||
LHX5 | LIM homeobox 5 | 0.191 | ||
SNTA1 | syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component) | 0.190 | ||
HLA-DOA | major histocompatibility complex, class II, DO alpha | 0.190 | ||
NCF1 | neutrophil cytosolic factor 1 | 0.190 | ||
PVRL3 | poliovirus receptor-related 3 | 0.189 | ||
IL10RA | interleukin 10 receptor, alpha | 0.188 | ||
DDR1 | discoidin domain receptor tyrosine kinase 1 | 0.188 | ||
BDNF | brain-derived neurotrophic factor | 0.188 | Human | |
TWF2 | twinfilin, actin-binding protein, homolog 2 (Drosophila) | 0.188 | ||
COL6A1 | collagen, type VI, alpha 1 | 0.187 | ||
SMAD6 | SMAD family member 6 | 0.187 | ||
CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.186 | ||
EFNA5 | ephrin-A5 | 0.186 | ||
PLD2 | phospholipase D2 | 0.186 | ||
GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.186 | Rat | |
EFNB1 | ephrin-B1 | 0.185 | ||
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.185 | ||
GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.185 | ||
PIK3CD | phosphoinositide-3-kinase, catalytic, delta polypeptide | 0.184 | Human | |
CCL20 | chemokine (C-C motif) ligand 20 | 0.183 | Human | |
KCNJ5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.183 | ||
PLEK | pleckstrin | 0.183 | ||
NOTCH4 | notch 4 | 0.182 | ||
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.182 | ||
NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.182 | ||
WNT2 | wingless-type MMTV integration site family member 2 | 0.182 | Human | |
ANGPT1 | angiopoietin 1 | 0.181 | ||
RGS1 | regulator of G-protein signaling 1 | 0.180 | ||
NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 0.180 | ||
MYLK2 | myosin light chain kinase 2 | 0.180 | ||
ZNF91 | zinc finger protein 91 | 0.179 | ||
MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 0.179 | ||
IL13 | interleukin 13 | 0.178 | ||
MED1 | mediator complex subunit 1 | 0.177 | ||
CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.177 | ||
CCR2 | chemokine (C-C motif) receptor 2 | 0.177 | Human Rat | |
FGF10 | fibroblast growth factor 10 | 0.176 | ||
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.176 | ||
CTSB | cathepsin B | 0.176 | ||
PLXND1 | plexin D1 | 0.176 | ||
UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.176 | ||
MAPKAPK3 | mitogen-activated protein kinase-activated protein kinase 3 | 0.176 | Fly | |
UBE2V2 | ubiquitin-conjugating enzyme E2 variant 2 | 0.175 | ||
STAT5A | signal transducer and activator of transcription 5A | 0.175 | ||
CD300C | CD300c molecule | 0.175 | Human | |
EFNB2 | ephrin-B2 | 0.174 | ||
COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.174 | ||
SESN2 | sestrin 2 | 0.174 | ||
GJD2 | gap junction protein, delta 2, 36kDa | 0.174 | ||
YES1 | v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1 | 0.173 | ||
IL7R | interleukin 7 receptor | 0.172 | ||
NLRP3 | NLR family, pyrin domain containing 3 | 0.172 | Human | |
WIPF1 | WAS/WASL interacting protein family, member 1 | 0.171 | ||
SELPLG | selectin P ligand | 0.171 | ||
SP1 | Sp1 transcription factor | 0.171 | ||
LDB1 | LIM domain binding 1 | 0.171 | ||
FGFR4 | fibroblast growth factor receptor 4 | 0.170 | ||
MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.170 | ||
TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.170 | ||
CD37 | CD37 molecule | 0.170 | ||
ANXA7 | annexin A7 | 0.170 | ||
TK1 | thymidine kinase 1, soluble | 0.170 | ||
MADCAM1 | mucosal vascular addressin cell adhesion molecule 1 | 0.170 | ||
ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.170 | ||
CCL19 | chemokine (C-C motif) ligand 19 | 0.170 | ||
DUSP4 | dual specificity phosphatase 4 | 0.169 | Human Rat | |
CLCN1 | chloride channel 1, skeletal muscle | 0.169 | ||
MMP16 | matrix metallopeptidase 16 (membrane-inserted) | 0.168 | ||
ZNF430 | zinc finger protein 430 | 0.168 | Human | |
NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.167 | ||
EVI2A | ecotropic viral integration site 2A | 0.167 | ||
IRF8 | interferon regulatory factor 8 | 0.167 | ||
RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.167 | ||
TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.167 | ||
CSF3 | colony stimulating factor 3 (granulocyte) | 0.166 | ||
DRD1 | dopamine receptor D1 | 0.166 | Human | |
NCOR2 | nuclear receptor corepressor 2 | 0.166 | Human | |
CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.166 | ||
TG | thyroglobulin | 0.166 | ||
GABPA | GA binding protein transcription factor, alpha subunit 60kDa | 0.166 | ||
CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.165 | ||
IL2RG | interleukin 2 receptor, gamma | 0.164 | ||
ITGB5 | integrin, beta 5 | 0.164 | ||
CYTIP | cytohesin 1 interacting protein | 0.164 | ||
SLIT3 | slit homolog 3 (Drosophila) | 0.164 | ||
F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.164 | ||
MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.163 | ||
CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.163 | ||
ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.162 | ||
RALBP1 | ralA binding protein 1 | 0.161 | ||
KLHL3 | kelch-like 3 (Drosophila) | 0.161 | ||
CLEC3B | C-type lectin domain family 3, member B | 0.161 | ||
RUNX2 | runt-related transcription factor 2 | 0.161 | ||
DDAH2 | dimethylarginine dimethylaminohydrolase 2 | 0.161 | ||
CH25H | cholesterol 25-hydroxylase | 0.160 | ||
FGF18 | fibroblast growth factor 18 | 0.160 | ||
ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 0.159 | ||
IL9R | interleukin 9 receptor | 0.159 | ||
CCL13 | chemokine (C-C motif) ligand 13 | 0.159 | Human | |
MOBKL1B | MOB1, Mps One Binder kinase activator-like 1B (yeast) | 0.159 | ||
CCR4 | chemokine (C-C motif) receptor 4 | 0.158 | Human | |
SOCS1 | suppressor of cytokine signaling 1 | 0.158 | ||
ACTB | actin, beta | 0.158 | ||
ANGPT2 | angiopoietin 2 | 0.157 | Human | |
MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.157 | ||
UBC | ubiquitin C | 0.157 | ||
SMAD5 | SMAD family member 5 | 0.157 | ||
TRAF4 | TNF receptor-associated factor 4 | 0.157 | ||
CSF1 | colony stimulating factor 1 (macrophage) | 0.156 | ||
PRKCB | protein kinase C, beta | 0.156 | ||
TRIM32 | tripartite motif containing 32 | 0.156 | ||
ZNF496 | zinc finger protein 496 | 0.156 | ||
TCF3 | transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47) | 0.155 | ||
EPHB2 | EPH receptor B2 | 0.155 | Human | |
SIT1 | signaling threshold regulating transmembrane adaptor 1 | 0.155 | ||
PRDM8 | PR domain containing 8 | 0.154 | ||
CRYBB1 | crystallin, beta B1 | 0.154 | ||
TNXB | tenascin XB | 0.154 | Mouse | |
CRP | C-reactive protein, pentraxin-related | 0.154 | ||
NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.153 | ||
FLT4 | fms-related tyrosine kinase 4 | 0.153 | ||
IL32 | interleukin 32 | 0.152 | ||
LIMK1 | LIM domain kinase 1 | 0.152 | ||
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.151 | ||
TRADD | TNFRSF1A-associated via death domain | 0.151 | ||
ARRDC3 | arrestin domain containing 3 | 0.151 | ||
NPY2R | neuropeptide Y receptor Y2 | 0.151 | ||
GOPC | golgi-associated PDZ and coiled-coil motif containing | 0.150 | ||
FYB | FYN binding protein | 0.150 | ||
UBASH3A | ubiquitin associated and SH3 domain containing A | 0.150 | ||
TPBG | trophoblast glycoprotein | 0.150 | ||
ELK1 | ELK1, member of ETS oncogene family | 0.150 | ||
ZNF117 | zinc finger protein 117 | 0.150 | Human | |
MSR1 | macrophage scavenger receptor 1 | 0.150 | ||
OXSR1 | oxidative-stress responsive 1 | 0.149 | ||
WNT11 | wingless-type MMTV integration site family, member 11 | 0.148 | Human | |
PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.148 | ||
IL2RB | interleukin 2 receptor, beta | 0.148 | ||
ELN | elastin | 0.148 | ||
PSG4 | pregnancy specific beta-1-glycoprotein 4 | 0.148 | ||
CCR3 | chemokine (C-C motif) receptor 3 | 0.147 | Human Rat | |
PGF | placental growth factor | 0.146 | Human | |
POU2F2 | POU class 2 homeobox 2 | 0.146 | Human | |
IRF3 | interferon regulatory factor 3 | 0.146 | ||
CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit | 0.146 | ||
SGK1 | serum/glucocorticoid regulated kinase 1 | 0.145 | ||
PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.145 | ||
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.145 | ||
TMC8 | transmembrane channel-like 8 | 0.145 | ||
ZNF254 | zinc finger protein 254 | 0.145 | Human | |
SNAI1 | snail homolog 1 (Drosophila) | 0.145 | ||
MBP | myelin basic protein | 0.145 | ||
GADD45B | growth arrest and DNA-damage-inducible, beta | 0.144 | ||
CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 | 0.144 | ||
FRA10AC1 | fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 | 0.143 | ||
RPL11 | ribosomal protein L11 | 0.143 | ||
STAB1 | stabilin 1 | 0.143 | ||
LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.143 | ||
ADAM15 | ADAM metallopeptidase domain 15 | 0.143 | ||
RHOB | ras homolog gene family, member B | 0.143 | ||
MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.142 | ||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.142 | ||
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.142 | Human Mouse | |
PXN | paxillin | 0.142 | Mouse | |
NCSTN | nicastrin | 0.141 | ||
RCHY1 | ring finger and CHY zinc finger domain containing 1 | 0.141 | ||
SPRY2 | sprouty homolog 2 (Drosophila) | 0.141 | ||
JAK3 | Janus kinase 3 | 0.141 | ||
TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.141 | ||
CALCR | calcitonin receptor | 0.140 | ||
INA | internexin neuronal intermediate filament protein, alpha | 0.140 | ||
CHIT1 | chitinase 1 (chitotriosidase) | 0.140 | Human | |
GFAP | glial fibrillary acidic protein | 0.139 | ||
ADRB2 | adrenergic, beta-2-, receptor, surface | 0.139 | ||
FES | feline sarcoma oncogene | 0.138 | ||
DPYSL4 | dihydropyrimidinase-like 4 | 0.138 | ||
MED15 | mediator complex subunit 15 | 0.138 | ||
PNRC2 | proline-rich nuclear receptor coactivator 2 | 0.137 | ||
CDCP1 | CUB domain containing protein 1 | 0.137 | ||
PGR | progesterone receptor | 0.137 | ||
THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 0.137 | ||
PSTPIP1 | proline-serine-threonine phosphatase interacting protein 1 | 0.137 | ||
ATF5 | activating transcription factor 5 | 0.137 | ||
WNT7A | wingless-type MMTV integration site family, member 7A | 0.136 | Human Rat | |
PTPN2 | protein tyrosine phosphatase, non-receptor type 2 | 0.136 | Mouse | |
LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.136 | ||
PPARA | peroxisome proliferator-activated receptor alpha | 0.136 | ||
DEF6 | differentially expressed in FDCP 6 homolog (mouse) | 0.136 | ||
CD2AP | CD2-associated protein | 0.135 | ||
SOX21 | SRY (sex determining region Y)-box 21 | 0.135 | ||
GADD45G | growth arrest and DNA-damage-inducible, gamma | 0.135 | ||
CCL1 | chemokine (C-C motif) ligand 1 | 0.134 | Human | |
EREG | epiregulin | 0.134 | ||
GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | 0.134 | ||
PTPRF | protein tyrosine phosphatase, receptor type, F | 0.134 | ||
PAX3 | paired box 3 | 0.134 | ||
GADD45GIP1 | growth arrest and DNA-damage-inducible, gamma interacting protein 1 | 0.134 | ||
CRYGC | crystallin, gamma C | 0.134 | ||
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.133 | ||
CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | 0.133 | Rat | |
SP110 | SP110 nuclear body protein | 0.133 | ||
EMILIN1 | elastin microfibril interfacer 1 | 0.133 | ||
SH3D19 | SH3 domain containing 19 | 0.133 | ||
LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.133 | ||
RTKN | rhotekin | 0.133 | ||
CD34 | CD34 molecule | 0.133 | ||
CA4 | carbonic anhydrase IV | 0.133 | ||
EPHA3 | EPH receptor A3 | 0.132 | Human | |
ITK | IL2-inducible T-cell kinase | 0.132 | ||
IL6R | interleukin 6 receptor | 0.132 | ||
BIN2 | bridging integrator 2 | 0.132 | ||
PDCD1 | programmed cell death 1 | 0.131 | ||
DPT | dermatopontin | 0.131 | ||
ACAN | aggrecan | 0.131 | ||
C2 | complement component 2 | 0.131 | ||
MARCO | macrophage receptor with collagenous structure | 0.131 | ||
SF1 | splicing factor 1 | 0.131 | ||
HTT | huntingtin | 0.131 | ||
MEFV | Mediterranean fever | 0.131 | ||
NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.130 | ||
KDM6B | lysine (K)-specific demethylase 6B | 0.130 | ||
THBS2 | thrombospondin 2 | 0.130 | Human | |
TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.130 | Human | |
NTN1 | netrin 1 | 0.130 | ||
RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 | 0.130 | Mouse | |
CCL14 | chemokine (C-C motif) ligand 14 | 0.130 | Human | |
CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.130 | ||
PARD3 | par-3 partitioning defective 3 homolog (C. elegans) | 0.129 | ||
FURIN | furin (paired basic amino acid cleaving enzyme) | 0.129 | ||
SIKE1 | suppressor of IKBKE 1 | 0.128 | ||
TYRP1 | tyrosinase-related protein 1 | 0.127 | ||
KCNA4 | potassium voltage-gated channel, shaker-related subfamily, member 4 | 0.127 | ||
P2RX3 | purinergic receptor P2X, ligand-gated ion channel, 3 | 0.127 | ||
FBLN1 | fibulin 1 | 0.127 | ||
SELE | selectin E | 0.127 | ||
SRI | sorcin | 0.127 | ||
IGSF6 | immunoglobulin superfamily, member 6 | 0.126 | ||
KLF5 | Kruppel-like factor 5 (intestinal) | 0.126 | ||
BLK | B lymphoid tyrosine kinase | 0.126 | ||
ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.126 | ||
SLC6A7 | solute carrier family 6 (neurotransmitter transporter, L-proline), member 7 | 0.126 | ||
PLXDC1 | plexin domain containing 1 | 0.126 | ||
TMC6 | transmembrane channel-like 6 | 0.125 | ||
HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 0.125 | Human | |
FOSL2 | FOS-like antigen 2 | 0.125 | ||
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.125 | ||
RAB1A | RAB1A, member RAS oncogene family | 0.125 | ||
STRN4 | striatin, calmodulin binding protein 4 | 0.125 | ||
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.125 | ||
TRIM33 | tripartite motif containing 33 | 0.124 | ||
ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 | 0.124 | ||
PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) | 0.124 | ||
CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.124 | ||
AZIN1 | antizyme inhibitor 1 | 0.124 | ||
PKN2 | protein kinase N2 | 0.124 | ||
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.124 | ||
BAI1 | brain-specific angiogenesis inhibitor 1 | 0.124 | ||
MED13 | mediator complex subunit 13 | 0.123 | ||
HDAC7 | histone deacetylase 7 | 0.123 | ||
RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.123 | ||
PRKCI | protein kinase C, iota | 0.123 | Human | |
C1R | complement component 1, r subcomponent | 0.123 | ||
S100A12 | S100 calcium binding protein A12 | 0.122 | ||
PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.122 | ||
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.122 | ||
MAP2 | microtubule-associated protein 2 | 0.122 | ||
PLXNB2 | plexin B2 | 0.122 | ||
RAB10 | RAB10, member RAS oncogene family | 0.122 | ||
CRYAA | crystallin, alpha A | 0.122 | ||
FGF5 | fibroblast growth factor 5 | 0.121 | Human | |
WISP1 | WNT1 inducible signaling pathway protein 1 | 0.121 | Human | |
AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.121 | Human | |
ERG | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 0.121 | ||
NDP | Norrie disease (pseudoglioma) | 0.121 | ||
ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.121 |