IMP: Integrative Multi-species Prediction

Homo sapiens

162 genes annotated in human

Multi-species View

regulation of i kappab kinase nf kappab signaling

GO:0043122

Any process that modulates I-kappaB kinase/NF-kappaB signaling.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of i kappab kinase nf kappab signaling"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of i kappab kinase nf kappab signaling" (in gray)

Name	Description	Probability	Func Analog Organism
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	1.000
TRAF6	TNF receptor-associated factor 6	1.000
BIRC3	baculoviral IAP repeat containing 3	1.000	Human
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	1.000
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	1.000
RIPK2	receptor-interacting serine-threonine kinase 2	1.000
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	1.000
XIAP	X-linked inhibitor of apoptosis	1.000	Human
SQSTM1	sequestosome 1	1.000
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	1.000	Human
CASP8	caspase 8, apoptosis-related cysteine peptidase	1.000
TRAF1	TNF receptor-associated factor 1	1.000	Human
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	1.000
MAP3K7	mitogen-activated protein kinase kinase kinase 7	1.000
UBC	ubiquitin C	1.000
MYD88	myeloid differentiation primary response gene (88)	1.000
TRAF2	TNF receptor-associated factor 2	1.000	Human
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.999	Human
BIRC2	baculoviral IAP repeat containing 2	0.999
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.998
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.997
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.997	Human
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.997
TRAF3	TNF receptor-associated factor 3	0.996	Human
CFLAR	CASP8 and FADD-like apoptosis regulator	0.991
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.988
FAS	Fas (TNF receptor superfamily, member 6)	0.988	Human
CHUK	conserved helix-loop-helix ubiquitous kinase	0.987	Human Zebrafish Mouse
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.984
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.982
TRIM63	tripartite motif containing 63	0.980	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.973
TNIP2	TNFAIP3 interacting protein 2	0.969
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.967
SMAD3	SMAD family member 3	0.965
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.964
TRADD	TNFRSF1A-associated via death domain	0.959
ESR1	estrogen receptor 1	0.958
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.953
FADD	Fas (TNFRSF6)-associated via death domain	0.945
C1QA	complement component 1, q subcomponent, A chain	0.945	Human
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.938
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.936	Human
CD40	CD40 molecule, TNF receptor superfamily member 5	0.935
TNF	tumor necrosis factor	0.921
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.903
CARD11	caspase recruitment domain family, member 11	0.902	Human Mouse
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.893	Human
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.888
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.887
S100A6	S100 calcium binding protein A6	0.874	Human
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.868	Human Rat
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.868
BCL10	B-cell CLL/lymphoma 10	0.866
PML	promyelocytic leukemia	0.864
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.862
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.852	Human
ICAM1	intercellular adhesion molecule 1	0.825
IRAK2	interleukin-1 receptor-associated kinase 2	0.817	Human
S100A9	S100 calcium binding protein A9	0.803	Human
TANK	TRAF family member-associated NFKB activator	0.798
TLR4	toll-like receptor 4	0.797
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.796
TRAF5	TNF receptor-associated factor 5	0.760
CAV1	caveolin 1, caveolae protein, 22kDa	0.757
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.749
ANXA2	annexin A2	0.729
CCL4	chemokine (C-C motif) ligand 4	0.695	Human
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.694
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.680
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.673	Human
IL1R1	interleukin 1 receptor, type I	0.665
S100A8	S100 calcium binding protein A8	0.662	Human
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.654
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.645
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.626
CXCL9	chemokine (C-X-C motif) ligand 9	0.624
IL8	interleukin 8	0.610
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.608
S100A16	S100 calcium binding protein A16	0.599	Human
S100A11	S100 calcium binding protein A11	0.568	Human
ANXA1	annexin A1	0.559
BCL3	B-cell CLL/lymphoma 3	0.549
SMAD7	SMAD family member 7	0.544
CXCL10	chemokine (C-X-C motif) ligand 10	0.535
S100A14	S100 calcium binding protein A14	0.533	Human
MYH9	myosin, heavy chain 9, non-muscle	0.531
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.518
IL2RB	interleukin 2 receptor, beta	0.514
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.506
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.490
TBK1	TANK-binding kinase 1	0.488
INSR	insulin receptor	0.486
CCR5	chemokine (C-C motif) receptor 5	0.485
CCL2	chemokine (C-C motif) ligand 2	0.479	Human
UBQLN1	ubiquilin 1	0.479
EEF1G	eukaryotic translation elongation factor 1 gamma	0.474
TLR2	toll-like receptor 2	0.466
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.461
IRF1	interferon regulatory factor 1	0.460
RNF11	ring finger protein 11	0.430
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.426
CCL22	chemokine (C-C motif) ligand 22	0.424	Human
TNIP1	TNFAIP3 interacting protein 1	0.422
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.421
MED15	mediator complex subunit 15	0.418
CXCL2	chemokine (C-X-C motif) ligand 2	0.416
TRIM21	tripartite motif containing 21	0.413	Human
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.410
ARHGAP1	Rho GTPase activating protein 1	0.406
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.405	Human
ACVR1B	activin A receptor, type IB	0.404
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.401
CALCOCO2	calcium binding and coiled-coil domain 2	0.400
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.392
TRIM5	tripartite motif containing 5	0.378
FASLG	Fas ligand (TNF superfamily, member 6)	0.377
CCL8	chemokine (C-C motif) ligand 8	0.377	Human
IRF7	interferon regulatory factor 7	0.373
DAXX	death-domain associated protein	0.372
TICAM2	toll-like receptor adaptor molecule 2	0.366
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.366
FLNA	filamin A, alpha	0.362
CCR7	chemokine (C-C motif) receptor 7	0.362
SNAI1	snail homolog 1 (Drosophila)	0.360
RANBP3	RAN binding protein 3	0.358
ZC3H12A	zinc finger CCCH-type containing 12A	0.351
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.350
STAT5A	signal transducer and activator of transcription 5A	0.349	Human
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.344
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.343
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.341	Human
USP15	ubiquitin specific peptidase 15	0.337
PLSCR1	phospholipid scramblase 1	0.335
CD14	CD14 molecule	0.328
IL4R	interleukin 4 receptor	0.326
ZRANB1	zinc finger, RAN-binding domain containing 1	0.323	Human
BAG3	BCL2-associated athanogene 3	0.320
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.319
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.317
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.315
FKBP4	FK506 binding protein 4, 59kDa	0.311
ARRB1	arrestin, beta 1	0.306
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.305	Human
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.302
RNF31	ring finger protein 31	0.302
MPDZ	multiple PDZ domain protein	0.295
CXCL3	chemokine (C-X-C motif) ligand 3	0.295
IL1R2	interleukin 1 receptor, type II	0.291
CCL20	chemokine (C-C motif) ligand 20	0.284	Human
PRKCA	protein kinase C, alpha	0.282
SOCS1	suppressor of cytokine signaling 1	0.278
C1QC	complement component 1, q subcomponent, C chain	0.278	Human
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.275
DIABLO	diablo, IAP-binding mitochondrial protein	0.275
PSEN1	presenilin 1	0.270
AREG	amphiregulin	0.268
APAF1	apoptotic peptidase activating factor 1	0.268
STAP2	signal transducing adaptor family member 2	0.266
TRIM43	tripartite motif containing 43	0.265
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.262
PIAS4	protein inhibitor of activated STAT, 4	0.259
IL6	interleukin 6 (interferon, beta 2)	0.258
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.257
PELI3	pellino homolog 3 (Drosophila)	0.255
ZNF84	zinc finger protein 84	0.254
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.253
S100A4	S100 calcium binding protein A4	0.248
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.248
ZNRF1	zinc and ring finger 1	0.246
NLRC4	NLR family, CARD domain containing 4	0.242
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.238
FBXO7	F-box protein 7	0.238
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.236
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.235
S100B	S100 calcium binding protein B	0.231
ZMYND11	zinc finger, MYND-type containing 11	0.227
IL1RN	interleukin 1 receptor antagonist	0.226	Human
OPTN	optineurin	0.223
ACTN4	actinin, alpha 4	0.223
MX2	myxovirus (influenza virus) resistance 2 (mouse)	0.217
NUMBL	numb homolog (Drosophila)-like	0.215
C1QB	complement component 1, q subcomponent, B chain	0.210	Human
TXN	thioredoxin	0.210
TRIM39	tripartite motif containing 39	0.208	Human
MYOZ1	myozenin 1	0.208
CXCL11	chemokine (C-X-C motif) ligand 11	0.208
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.204
TTN	titin	0.204
FTH1	ferritin, heavy polypeptide 1	0.204
PLAUR	plasminogen activator, urokinase receptor	0.202
IFNG	interferon, gamma	0.202
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.202
MAVS	mitochondrial antiviral signaling protein	0.201
CCL5	chemokine (C-C motif) ligand 5	0.200	Human
TMSB10	thymosin beta 10	0.197
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.197
SOD2	superoxide dismutase 2, mitochondrial	0.195
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.193
MAPK8	mitogen-activated protein kinase 8	0.193
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.193
S100P	S100 calcium binding protein P	0.189	Human
CCL19	chemokine (C-C motif) ligand 19	0.188
IL7R	interleukin 7 receptor	0.187
IL1B	interleukin 1, beta	0.186
GCC1	GRIP and coiled-coil domain containing 1	0.180
MYO1C	myosin IC	0.178
RUNX3	runt-related transcription factor 3	0.176
TRIM27	tripartite motif containing 27	0.175	Human
CCR1	chemokine (C-C motif) receptor 1	0.170
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.170
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.169	Human
CAPNS1	calpain, small subunit 1	0.168
ZNF420	zinc finger protein 420	0.167
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.167
PPP5C	protein phosphatase 5, catalytic subunit	0.166
IRF3	interferon regulatory factor 3	0.164
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.164
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.164	Human
TGIF1	TGFB-induced factor homeobox 1	0.163
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.162
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.162
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.158
PFN1	profilin 1	0.158
ELF4	E74-like factor 4 (ets domain transcription factor)	0.157
SOCS3	suppressor of cytokine signaling 3	0.156
CCL13	chemokine (C-C motif) ligand 13	0.155	Human
S100A1	S100 calcium binding protein A1	0.154	Human
PSEN2	presenilin 2 (Alzheimer disease 4)	0.154
PTPRC	protein tyrosine phosphatase, receptor type, C	0.154
CXCL5	chemokine (C-X-C motif) ligand 5	0.153
BTK	Bruton agammaglobulinemia tyrosine kinase	0.151
CCL7	chemokine (C-C motif) ligand 7	0.150	Human
UBASH3B	ubiquitin associated and SH3 domain containing B	0.148
EFCAB4B	EF-hand calcium binding domain 4B	0.146
S100A2	S100 calcium binding protein A2	0.144	Human
RXRA	retinoid X receptor, alpha	0.142
GSK3B	glycogen synthase kinase 3 beta	0.141
LMNA	lamin A/C	0.138
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.138
TICAM1	toll-like receptor adaptor molecule 1	0.137
DPP4	dipeptidyl-peptidase 4	0.137
STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	0.137	Human
HDAC1	histone deacetylase 1	0.136	Mouse
IL2RG	interleukin 2 receptor, gamma	0.135
OCLN	occludin	0.135
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.132
APOL3	apolipoprotein L, 3	0.131
IDO1	indoleamine 2,3-dioxygenase 1	0.130
CCR4	chemokine (C-C motif) receptor 4	0.130
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.129
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.129	Human
TIFA	TRAF-interacting protein with forkhead-associated domain	0.128
CREBBP	CREB binding protein	0.128
ZNF746	zinc finger protein 746	0.126
PRKCD	protein kinase C, delta	0.125
MAP2K5	mitogen-activated protein kinase kinase 5	0.124
TRIM34	tripartite motif containing 34	0.123
IL12RB2	interleukin 12 receptor, beta 2	0.123
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.122
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.122
HDAC7	histone deacetylase 7	0.122
IL10	interleukin 10	0.121
CCL3	chemokine (C-C motif) ligand 3	0.121	Human
IFIH1	interferon induced with helicase C domain 1	0.121
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.120
HSF1	heat shock transcription factor 1	0.119
SMAD4	SMAD family member 4	0.119
MEFV	Mediterranean fever	0.119
GBP1	guanylate binding protein 1, interferon-inducible	0.119
JAK2	Janus kinase 2	0.119
BCL2A1	BCL2-related protein A1	0.118
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.116
RHOG	ras homolog gene family, member G (rho G)	0.116
IRF9	interferon regulatory factor 9	0.116
IL18RAP	interleukin 18 receptor accessory protein	0.116
NOTCH1	notch 1	0.115
PYCARD	PYD and CARD domain containing	0.114
PYDC2	pyrin domain containing 2	0.112
CXCL13	chemokine (C-X-C motif) ligand 13	0.110
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.110
GFI1B	growth factor independent 1B transcription repressor	0.110
PIAS2	protein inhibitor of activated STAT, 2	0.110
NCF1	neutrophil cytosolic factor 1	0.109
EEF1D	eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)	0.109
TMEM173	transmembrane protein 173	0.109
TRAF3IP2	TRAF3 interacting protein 2	0.108
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.108
MYLK2	myosin light chain kinase 2	0.108
VCAM1	vascular cell adhesion molecule 1	0.107
TJP1	tight junction protein 1 (zona occludens 1)	0.106
EP300	E1A binding protein p300	0.106
LASP1	LIM and SH3 protein 1	0.106
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.105
PI3	peptidase inhibitor 3, skin-derived	0.105
GSN	gelsolin	0.105
TEK	TEK tyrosine kinase, endothelial	0.105
RNF185	ring finger protein 185	0.104
FAM101B	family with sequence similarity 101, member B	0.104
OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa	0.103
GFM1	G elongation factor, mitochondrial 1	0.103
YY1	YY1 transcription factor	0.102
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.101
ARIH2	ariadne homolog 2 (Drosophila)	0.100
TRIM41	tripartite motif containing 41	0.100	Human
SFN	stratifin	0.099
SOX7	SRY (sex determining region Y)-box 7	0.099
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.099
UBE2W	ubiquitin-conjugating enzyme E2W (putative)	0.098
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.097
ZNF260	zinc finger protein 260	0.097
ITGB7	integrin, beta 7	0.097
RIN1	Ras and Rab interactor 1	0.095
IL32	interleukin 32	0.095
TRIM26	tripartite motif containing 26	0.095
SNX5	sorting nexin 5	0.094
CD7	CD7 molecule	0.094
MESDC2	mesoderm development candidate 2	0.094
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.094	Human
LRSAM1	leucine rich repeat and sterile alpha motif containing 1	0.094
IGSF6	immunoglobulin superfamily, member 6	0.094
NXF1	nuclear RNA export factor 1	0.093
USP38	ubiquitin specific peptidase 38	0.093
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.093
IRF4	interferon regulatory factor 4	0.092
IDE	insulin-degrading enzyme	0.092
CCDC85B	coiled-coil domain containing 85B	0.092
MARCH5	membrane-associated ring finger (C3HC4) 5	0.092
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	0.092	Human
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.091
HIPK2	homeodomain interacting protein kinase 2	0.091
TYMP	thymidine phosphorylase	0.090
UBD	ubiquitin D	0.090
LIN28B	lin-28 homolog B (C. elegans)	0.089
JAK3	Janus kinase 3	0.088
APOL1	apolipoprotein L, 1	0.088	Human
TRAF7	TNF receptor-associated factor 7	0.087
NOD2	nucleotide-binding oligomerization domain containing 2	0.087
USP2	ubiquitin specific peptidase 2	0.087
C3	complement component 3	0.086
RARA	retinoic acid receptor, alpha	0.085
NCOA1	nuclear receptor coactivator 1	0.085
SBF1	SET binding factor 1	0.084
IL15RA	interleukin 15 receptor, alpha	0.084
ITK	IL2-inducible T-cell kinase	0.084
PTEN	phosphatase and tensin homolog	0.084
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.083
STAT4	signal transducer and activator of transcription 4	0.083	Human
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.083
C1orf93	chromosome 1 open reading frame 93	0.082
LGALS9	lectin, galactoside-binding, soluble, 9	0.082
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.082
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.082
UBQLN4	ubiquilin 4	0.082
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.082
CCL1	chemokine (C-C motif) ligand 1	0.082	Human
ZNF263	zinc finger protein 263	0.081
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.081
MARCO	macrophage receptor with collagenous structure	0.080
UBASH3A	ubiquitin associated and SH3 domain containing A	0.080
AZI2	5-azacytidine induced 2	0.079
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.079
GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	0.079
TGFBR1	transforming growth factor, beta receptor 1	0.079
KCNE3	potassium voltage-gated channel, Isk-related family, member 3	0.078
S100A12	S100 calcium binding protein A12	0.078
GJB3	gap junction protein, beta 3, 31kDa	0.078
C10orf54	chromosome 10 open reading frame 54	0.077
AHNAK	AHNAK nucleoprotein	0.077
TRIM22	tripartite motif containing 22	0.077
CCR3	chemokine (C-C motif) receptor 3	0.077
CSF1	colony stimulating factor 1 (macrophage)	0.076
TRIM32	tripartite motif containing 32	0.076
LGALS3	lectin, galactoside-binding, soluble, 3	0.076	Human
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.076
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.075
ZNF585A	zinc finger protein 585A	0.075
IL4	interleukin 4	0.075
JUN	jun proto-oncogene	0.075
FBLIM1	filamin binding LIM protein 1	0.074	Human
RNF181	ring finger protein 181	0.073
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.073
MED25	mediator complex subunit 25	0.073
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.073
IER3	immediate early response 3	0.072
RIPK3	receptor-interacting serine-threonine kinase 3	0.072	Human
NEB	nebulin	0.072
G6PD	glucose-6-phosphate dehydrogenase	0.072
EZR	ezrin	0.072
MICA	MHC class I polypeptide-related sequence A	0.072
CLEC10A	C-type lectin domain family 10, member A	0.071
SERTAD1	SERTA domain containing 1	0.070
STRN3	striatin, calmodulin binding protein 3	0.070
DYDC1	DPY30 domain containing 1	0.070
IL15	interleukin 15	0.070
KLF5	Kruppel-like factor 5 (intestinal)	0.069
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.069
IRAK4	interleukin-1 receptor-associated kinase 4	0.069
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.068
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.068	Human
LRP10	low density lipoprotein receptor-related protein 10	0.068
STX11	syntaxin 11	0.067
ZHX1	zinc fingers and homeoboxes 1	0.067
APP	amyloid beta (A4) precursor protein	0.067
CCL17	chemokine (C-C motif) ligand 17	0.066	Human
AQP9	aquaporin 9	0.066
LCN2	lipocalin 2	0.066
ZNF304	zinc finger protein 304	0.066
ECM1	extracellular matrix protein 1	0.066
TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B	0.066
IFNGR1	interferon gamma receptor 1	0.065
MKRN1	makorin ring finger protein 1	0.065
KDM2A	lysine (K)-specific demethylase 2A	0.065
NOD1	nucleotide-binding oligomerization domain containing 1	0.064
TRIM52	tripartite motif containing 52	0.064	Human
CFP	complement factor properdin	0.063
SLAMF7	SLAM family member 7	0.063
IL1RAP	interleukin 1 receptor accessory protein	0.063
SLAMF8	SLAM family member 8	0.063
EMP3	epithelial membrane protein 3	0.063
DAZAP2	DAZ associated protein 2	0.063
GABARAPL1	GABA(A) receptor-associated protein like 1	0.063
CCL11	chemokine (C-C motif) ligand 11	0.063	Human
FAM190B	family with sequence similarity 190, member B	0.063
PRKCZ	protein kinase C, zeta	0.063
GPR109B	G protein-coupled receptor 109B	0.062
KYNU	kynureninase	0.062
IL21R	interleukin 21 receptor	0.062
USP9X	ubiquitin specific peptidase 9, X-linked	0.062
NLRP3	NLR family, pyrin domain containing 3	0.061
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.061
HSPA1L	heat shock 70kDa protein 1-like	0.061
SKIL	SKI-like oncogene	0.061
PCDHA4	protocadherin alpha 4	0.061
HOXA9	homeobox A9	0.061
POLI	polymerase (DNA directed) iota	0.061
VCL	vinculin	0.061
IL18	interleukin 18 (interferon-gamma-inducing factor)	0.060
MVP	major vault protein	0.060
CXCR2	chemokine (C-X-C motif) receptor 2	0.060
HK3	hexokinase 3 (white cell)	0.060
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.060
FLNB	filamin B, beta	0.059	Human
TMEM176A	transmembrane protein 176A	0.059
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.059
ZNF473	zinc finger protein 473	0.059
C15orf39	chromosome 15 open reading frame 39	0.059
APOL2	apolipoprotein L, 2	0.058
ZNF302	zinc finger protein 302	0.058	Human
LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.058
NMI	N-myc (and STAT) interactor	0.058
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.058
ADAMDEC1	ADAM-like, decysin 1	0.058
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.058
CCNT1	cyclin T1	0.058
CD40LG	CD40 ligand	0.058
NOG	noggin	0.057
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.057
CD83	CD83 molecule	0.057
CCDC50	coiled-coil domain containing 50	0.057
EREG	epiregulin	0.057
RNF111	ring finger protein 111	0.057
RARRES3	retinoic acid receptor responder (tazarotene induced) 3	0.057
CYTIP	cytohesin 1 interacting protein	0.057
FPR3	formyl peptide receptor 3	0.057
IL1A	interleukin 1, alpha	0.056	Human
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.056
SPOP	speckle-type POZ protein	0.056
BCL2L1	BCL2-like 1	0.056
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.056
CD69	CD69 molecule	0.055
CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)	0.055
EDAR	ectodysplasin A receptor	0.055
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.055
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.054
CMKLR1	chemokine-like receptor 1	0.054
JAG2	jagged 2	0.054
ELK1	ELK1, member of ETS oncogene family	0.054
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.054
PRDM1	PR domain containing 1, with ZNF domain	0.054
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.053
IL18R1	interleukin 18 receptor 1	0.053	Mouse
NUCB2	nucleobindin 2	0.053
SLC15A3	solute carrier family 15, member 3	0.053
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.053
KLF2	Kruppel-like factor 2 (lung)	0.053
AOAH	acyloxyacyl hydrolase (neutrophil)	0.052
CSNK1D	casein kinase 1, delta	0.052
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.052
PELI1	pellino homolog 1 (Drosophila)	0.052	Mouse
ZBTB8A	zinc finger and BTB domain containing 8A	0.052
ACTA1	actin, alpha 1, skeletal muscle	0.052
VNN2	vanin 2	0.052
FBXW11	F-box and WD repeat domain containing 11	0.051	Mouse Fly
TMED10	transmembrane emp24-like trafficking protein 10 (yeast)	0.051
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.051
KLRK1	killer cell lectin-like receptor subfamily K, member 1	0.051
DARC	Duffy blood group, chemokine receptor	0.051
SP110	SP110 nuclear body protein	0.051
TREM1	triggering receptor expressed on myeloid cells 1	0.051
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.051
AGER	advanced glycosylation end product-specific receptor	0.051
C9orf89	chromosome 9 open reading frame 89	0.051
CXCR6	chemokine (C-X-C motif) receptor 6	0.051
SIRT6	sirtuin 6	0.051
FTL	ferritin, light polypeptide	0.051
EED	embryonic ectoderm development	0.051
XIRP1	xin actin-binding repeat containing 1	0.051
APOL6	apolipoprotein L, 6	0.050
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.050
AIM2	absent in melanoma 2	0.050
SMAD9	SMAD family member 9	0.050
YAP1	Yes-associated protein 1	0.050
RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1	0.050
CD163	CD163 molecule	0.050
CSTB	cystatin B (stefin B)	0.050
EBI3	Epstein-Barr virus induced 3	0.049
ZNF529	zinc finger protein 529	0.049
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.049	Rat
MAPK7	mitogen-activated protein kinase 7	0.049
KRT8	keratin 8	0.049
C3AR1	complement component 3a receptor 1	0.049
GNLY	granulysin	0.049
LAMP3	lysosomal-associated membrane protein 3	0.049
CLEC7A	C-type lectin domain family 7, member A	0.049
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.049
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.049
GLRX3	glutaredoxin 3	0.049
XPO6	exportin 6	0.049
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.049
GBP4	guanylate binding protein 4	0.048
PTGES	prostaglandin E synthase	0.048
ZNF224	zinc finger protein 224	0.048
MAGEA4	melanoma antigen family A, 4	0.048
RIPK4	receptor-interacting serine-threonine kinase 4	0.048	Human
ZNF432	zinc finger protein 432	0.048
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.048
ARRDC3	arrestin domain containing 3	0.048
POU2F2	POU class 2 homeobox 2	0.048
CTBP2	C-terminal binding protein 2	0.047
AKAP13	A kinase (PRKA) anchor protein 13	0.047
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.047
TP63	tumor protein p63	0.047
NUP54	nucleoporin 54kDa	0.047
PIM1	pim-1 oncogene	0.047
SPRR2A	small proline-rich protein 2A	0.047
TFPI2	tissue factor pathway inhibitor 2	0.047
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.047
SMAD5	SMAD family member 5	0.047
PDCD2	programmed cell death 2	0.047
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.047
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.047
RNF126	ring finger protein 126	0.047
SMAD1	SMAD family member 1	0.046
CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)	0.046
GORASP1	golgi reassembly stacking protein 1, 65kDa	0.046
CH25H	cholesterol 25-hydroxylase	0.046
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.046
ICOS	inducible T-cell co-stimulator	0.046
CHRD	chordin	0.046
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.046
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.046
ARL15	ADP-ribosylation factor-like 15	0.046
ASCC3	activating signal cointegrator 1 complex subunit 3	0.046
IL18BP	interleukin 18 binding protein	0.046
CSK	c-src tyrosine kinase	0.046	Human
SECTM1	secreted and transmembrane 1	0.046
CRMP1	collapsin response mediator protein 1	0.046
ZNF571	zinc finger protein 571	0.046
ZNF140	zinc finger protein 140	0.046	Human
KAT2B	K(lysine) acetyltransferase 2B	0.046
MTRNR2L1	MT-RNR2-like 1	0.046
PELI2	pellino homolog 2 (Drosophila)	0.046
KRT17	keratin 17	0.046
ICOSLG	inducible T-cell co-stimulator ligand	0.046
INHBA	inhibin, beta A	0.045
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.045
ZNF267	zinc finger protein 267	0.045
MTA1	metastasis associated 1	0.045
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.045
SAMD9L	sterile alpha motif domain containing 9-like	0.045
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.045
SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1	0.045
WDR26	WD repeat domain 26	0.045
TRIM14	tripartite motif containing 14	0.045
MYL12A	myosin, light chain 12A, regulatory, non-sarcomeric	0.045
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.045
MKRN3	makorin ring finger protein 3	0.045
TREM2	triggering receptor expressed on myeloid cells 2	0.044
IRS2	insulin receptor substrate 2	0.044
CCRL2	chemokine (C-C motif) receptor-like 2	0.044
MYH14	myosin, heavy chain 14, non-muscle	0.044
ZNF675	zinc finger protein 675	0.044
ADAP2	ArfGAP with dual PH domains 2	0.044
UBR4	ubiquitin protein ligase E3 component n-recognin 4	0.044
CD2	CD2 molecule	0.044
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	0.044
TRIM9	tripartite motif containing 9	0.044
YTHDF3	YTH domain family, member 3	0.044
ZNF211	zinc finger protein 211	0.044
PEA15	phosphoprotein enriched in astrocytes 15	0.044
TRIM8	tripartite motif containing 8	0.044
SETD7	SET domain containing (lysine methyltransferase) 7	0.044
SLAMF1	signaling lymphocytic activation molecule family member 1	0.044
CHIT1	chitinase 1 (chitotriosidase)	0.044
PGAM5	phosphoglycerate mutase family member 5	0.043
SELE	selectin E	0.043
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.043	Human
FCAR	Fc fragment of IgA, receptor for	0.043
XDH	xanthine dehydrogenase	0.043
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.043
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.043
GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	0.043
SLPI	secretory leukocyte peptidase inhibitor	0.043
CSTA	cystatin A (stefin A)	0.043
ARL4D	ADP-ribosylation factor-like 4D	0.043
HCP5	HLA complex P5	0.043
IGSF21	immunoglobin superfamily, member 21	0.043
SIAH1	seven in absentia homolog 1 (Drosophila)	0.043
CD274	CD274 molecule	0.042
FHL3	four and a half LIM domains 3	0.042
MUC1	mucin 1, cell surface associated	0.042
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.042
MLKL	mixed lineage kinase domain-like	0.042
BID	BH3 interacting domain death agonist	0.042
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.042
PKP4	plakophilin 4	0.042
RAD23A	RAD23 homolog A (S. cerevisiae)	0.042
EHD1	EH-domain containing 1	0.042
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.041
HTR4	5-hydroxytryptamine (serotonin) receptor 4	0.041	Human
CD28	CD28 molecule	0.041
MTA2	metastasis associated 1 family, member 2	0.041
CMIP	c-Maf-inducing protein	0.041
IRAK3	interleukin-1 receptor-associated kinase 3	0.041	Human
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.041
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.041
SIGLEC7	sialic acid binding Ig-like lectin 7	0.041
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.041
RHOC	ras homolog gene family, member C	0.040
MMP19	matrix metallopeptidase 19	0.040
ZFAND5	zinc finger, AN1-type domain 5	0.040	Human
SELL	selectin L	0.040
CD68	CD68 molecule	0.040
TRIM38	tripartite motif containing 38	0.040
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.040
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.040	Human
VNN1	vanin 1	0.040
FERMT2	fermitin family member 2	0.040
FPR1	formyl peptide receptor 1	0.040
RNF10	ring finger protein 10	0.040
JMJD6	jumonji domain containing 6	0.040
KMO	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)	0.040
SQRDL	sulfide quinone reductase-like (yeast)	0.039
LILRB5	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5	0.039
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.039
S100A7	S100 calcium binding protein A7	0.039
CXCR3	chemokine (C-X-C motif) receptor 3	0.039
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.039
PPP6C	protein phosphatase 6, catalytic subunit	0.039
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.039
TCAP	titin-cap (telethonin)	0.039
ITGB4	integrin, beta 4	0.039
MXD1	MAX dimerization protein 1	0.039
MAFIP	MAFF interacting protein	0.039
LRDD	leucine-rich repeats and death domain containing	0.039
RRAS	related RAS viral (r-ras) oncogene homolog	0.039
RBM12B	RNA binding motif protein 12B	0.039
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.039
CSF3	colony stimulating factor 3 (granulocyte)	0.039
CTTNBP2NL	CTTNBP2 N-terminal like	0.038
TUBB2B	tubulin, beta 2B	0.038
IL19	interleukin 19	0.038
TUBGCP4	tubulin, gamma complex associated protein 4	0.038
FKBP5	FK506 binding protein 5	0.038
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.038
TNNT1	troponin T type 1 (skeletal, slow)	0.038
MSC	musculin	0.038
ZNF569	zinc finger protein 569	0.038
MAPK9	mitogen-activated protein kinase 9	0.038
IK	IK cytokine, down-regulator of HLA II	0.038
PAFAH1B2	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	0.038
SP100	SP100 nuclear antigen	0.038
NLRC5	NLR family, CARD domain containing 5	0.038	Human
SERPINB9	serpin peptidase inhibitor, clade B (ovalbumin), member 9	0.038
FGFR1OP2	FGFR1 oncogene partner 2	0.038
COPB2	coatomer protein complex, subunit beta 2 (beta prime)	0.038
CD48	CD48 molecule	0.038
GPR171	G protein-coupled receptor 171	0.038
CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.038
CST7	cystatin F (leukocystatin)	0.037
C10orf46	chromosome 10 open reading frame 46	0.037
TFEC	transcription factor EC	0.037
ANKRD10	ankyrin repeat domain 10	0.037
JUNB	jun B proto-oncogene	0.037
STX16	syntaxin 16	0.037
TBX21	T-box 21	0.037
GBP2	guanylate binding protein 2, interferon-inducible	0.037
C1S	complement component 1, s subcomponent	0.037
TRAFD1	TRAF-type zinc finger domain containing 1	0.037
BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	0.037
TXK	TXK tyrosine kinase	0.037
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.037
MPRIP	myosin phosphatase Rho interacting protein	0.037
ATM	ataxia telangiectasia mutated	0.037
HTRA2	HtrA serine peptidase 2	0.037
MEX3C	mex-3 homolog C (C. elegans)	0.037
C19orf66	chromosome 19 open reading frame 66	0.037
C14orf1	chromosome 14 open reading frame 1	0.036
RUNX1	runt-related transcription factor 1	0.036
PDE4D	phosphodiesterase 4D, cAMP-specific	0.036
MT2A	metallothionein 2A	0.036
CARD6	caspase recruitment domain family, member 6	0.036
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.036
ACSL5	acyl-CoA synthetase long-chain family member 5	0.036
STEAP4	STEAP family member 4	0.036
PRKCQ	protein kinase C, theta	0.036	Rat
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.036
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.036
VMP1	vacuole membrane protein 1	0.036
ZNF83	zinc finger protein 83	0.036
TSGA10	testis specific, 10	0.036
PTAFR	platelet-activating factor receptor	0.036
SMAD2	SMAD family member 2	0.036
LY96	lymphocyte antigen 96	0.036
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.036
IRF8	interferon regulatory factor 8	0.036
LAMB3	laminin, beta 3	0.036
GIPC1	GIPC PDZ domain containing family, member 1	0.035
FPR2	formyl peptide receptor 2	0.035
TLR7	toll-like receptor 7	0.035
NCOA3	nuclear receptor coactivator 3	0.035
RAD52	RAD52 homolog (S. cerevisiae)	0.035
CD247	CD247 molecule	0.035
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.035
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.035
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.035
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.035
KRT6A	keratin 6A	0.035
TNFRSF4	tumor necrosis factor receptor superfamily, member 4	0.035
NINJ1	ninjurin 1	0.035
CLEC4E	C-type lectin domain family 4, member E	0.035
FFAR2	free fatty acid receptor 2	0.035
CDA	cytidine deaminase	0.035
STRN	striatin, calmodulin binding protein	0.035
LAD1	ladinin 1	0.035
SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7	0.035
VAMP5	vesicle-associated membrane protein 5 (myobrevin)	0.035
ZFP30	zinc finger protein 30 homolog (mouse)	0.034
IL1F5	interleukin 1 family, member 5 (delta)	0.034