IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

multicellular organismal aging

An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

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Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "multicellular organismal aging" (in gray)

Name	Description	Probability	Func Analog Organism
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	1.000	Worm
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.999	Worm
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.992	Worm
TP53	tumor protein p53	0.991	Mouse Worm Fly
SMAD3	SMAD family member 3	0.990
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.990
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.988
UQCRC2	ubiquinol-cytochrome c reductase core protein II	0.982
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.977	Worm
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.977
MAPK8	mitogen-activated protein kinase 8	0.975	Worm
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.974
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.973	Worm
YBX1	Y box binding protein 1	0.970
ARRB1	arrestin, beta 1	0.968
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.967	Fly
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.967
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.966	Worm
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.966	Worm
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.964
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.962	Worm
SMAD2	SMAD family member 2	0.960
EIF3K	eukaryotic translation initiation factor 3, subunit K	0.956
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.955
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.955	Worm
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.953
SQSTM1	sequestosome 1	0.951
SRSF2	serine/arginine-rich splicing factor 2	0.949
MAP2K4	mitogen-activated protein kinase kinase 4	0.945
BAG3	BCL2-associated athanogene 3	0.942
YY1	YY1 transcription factor	0.940
MAPK14	mitogen-activated protein kinase 14	0.936	Fly
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.932
WDR5	WD repeat domain 5	0.931	Worm
SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.930
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.930	Worm
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.929
SP1	Sp1 transcription factor	0.925
SIRT1	sirtuin 1	0.924	Worm Fly
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.923	Worm
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.922
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.915	Worm
PSMB3	proteasome (prosome, macropain) subunit, beta type, 3	0.915	Worm
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.913	Worm
FLNA	filamin A, alpha	0.911	Fly
NDUFS3	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	0.910	Worm
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.908
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.907	Worm
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.906	Worm
ILK	integrin-linked kinase	0.902	Worm
HSPA8	heat shock 70kDa protein 8	0.901	Worm
TXN	thioredoxin	0.899
HDAC2	histone deacetylase 2	0.896	Fly
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.893	Worm
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.885
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.883
IRS1	insulin receptor substrate 1	0.882	Fly
NBR1	neighbor of BRCA1 gene 1	0.881
TH1L	TH1-like (Drosophila)	0.880
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.879	Worm
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.878	Worm
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.872
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.870	Worm
PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.865
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.863	Worm
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.863	Worm
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.860	Worm
OXA1L	oxidase (cytochrome c) assembly 1-like	0.860
ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)	0.856
IGF1R	insulin-like growth factor 1 receptor	0.845	Worm Fly
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.844	Worm
JAG1	jagged 1	0.842
NCL	nucleolin	0.834
ARRB2	arrestin, beta 2	0.834
COX7B	cytochrome c oxidase subunit VIIb	0.828
PSMB4	proteasome (prosome, macropain) subunit, beta type, 4	0.825	Worm
VCP	valosin containing protein	0.824
UQCRH	ubiquinol-cytochrome c reductase hinge protein	0.823
HSF1	heat shock transcription factor 1	0.816	Worm
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.813	Worm
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.802
SYK	spleen tyrosine kinase	0.799
UQCRC1	ubiquinol-cytochrome c reductase core protein I	0.792	Worm
PBX1	pre-B-cell leukemia homeobox 1	0.789
CSNK2B	casein kinase 2, beta polypeptide	0.787
CREBBP	CREB binding protein	0.784	Worm
RARA	retinoic acid receptor, alpha	0.784
HSPB1	heat shock 27kDa protein 1	0.782	Worm Fly
RB1CC1	RB1-inducible coiled-coil 1	0.781
RPS3	ribosomal protein S3	0.780	Worm
UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.775
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.773	Worm
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.771
COX7A2	cytochrome c oxidase subunit VIIa polypeptide 2 (liver)	0.770
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.766
CRYAB	crystallin, alpha B	0.763	Fly
NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa	0.762	Fly
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.758	Worm
RBM39	RNA binding motif protein 39	0.753	Worm
TOP1	topoisomerase (DNA) I	0.739	Worm
COX4I1	cytochrome c oxidase subunit IV isoform 1	0.736	Worm
DCAF7	DDB1 and CUL4 associated factor 7	0.735
MCM3	minichromosome maintenance complex component 3	0.734
PSAP	prosaposin	0.727
EIF3L	eukaryotic translation initiation factor 3, subunit L	0.727
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.725	Worm
NOTCH1	notch 1	0.724	Worm Fly
EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	0.722
FKBP1A	FK506 binding protein 1A, 12kDa	0.722
ZFYVE9	zinc finger, FYVE domain containing 9	0.719	Worm
PGK1	phosphoglycerate kinase 1	0.716
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.709
DLAT	dihydrolipoamide S-acetyltransferase	0.708
PABPC1	poly(A) binding protein, cytoplasmic 1	0.707	Worm
MAPK1	mitogen-activated protein kinase 1	0.706	Worm
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.705
YAP1	Yes-associated protein 1	0.700
NCOA1	nuclear receptor coactivator 1	0.694
CREB1	cAMP responsive element binding protein 1	0.693
TPT1	tumor protein, translationally-controlled 1	0.693
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.692
SRPK2	SRSF protein kinase 2	0.691
GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.690
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.690
WDR83	WD repeat domain 83	0.688
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.687	Worm
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.685	Worm
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.684
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.683
PDHX	pyruvate dehydrogenase complex, component X	0.682
HSPA4	heat shock 70kDa protein 4	0.676	Worm
SLC25A3	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3	0.674	Worm
ATP5J	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6	0.673	Worm
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.670	Worm
HADHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	0.669	Fly
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.666	Worm
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	0.662
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.661	Worm
RPL3	ribosomal protein L3	0.652
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.651	Worm
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.650	Worm
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.650
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.646	Worm
RHOA	ras homolog gene family, member A	0.645
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.642
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.640
NDUFB9	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa	0.640
JUN	jun proto-oncogene	0.638	Fly
ATP5L	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G	0.636	Worm
C1QBP	complement component 1, q subcomponent binding protein	0.636
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.634
ZMYND11	zinc finger, MYND-type containing 11	0.629
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.627
ATP5O	ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit	0.626
RRAGA	Ras-related GTP binding A	0.625	Worm
ALAS1	aminolevulinate, delta-, synthase 1	0.625
PLEC	plectin	0.622
EXOSC3	exosome component 3	0.615
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.613
STK4	serine/threonine kinase 4	0.612	Worm
CRYGC	crystallin, gamma C	0.612
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.609	Worm
COX5B	cytochrome c oxidase subunit Vb	0.609	Worm
NDUFAB1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa	0.609	Worm
NONO	non-POU domain containing, octamer-binding	0.607
NDUFA4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa	0.607
HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4	0.605	Worm
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.598
PPIA	peptidylprolyl isomerase A (cyclophilin A)	0.598
COX5A	cytochrome c oxidase subunit Va	0.597	Worm
MAPK3	mitogen-activated protein kinase 3	0.594	Worm
FLNB	filamin B, beta	0.593	Fly
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.587	Fly
GRN	granulin	0.583
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.583
RPS16	ribosomal protein S16	0.582
LCK	lymphocyte-specific protein tyrosine kinase	0.576
PKM2	pyruvate kinase, muscle	0.575	Worm
RPS28	ribosomal protein S28	0.574
RXRA	retinoid X receptor, alpha	0.573	Worm
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.568
RPS18	ribosomal protein S18	0.568
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.565
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.565
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.563	Worm
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.561
STK3	serine/threonine kinase 3	0.561	Worm
TALDO1	transaldolase 1	0.561
RPS13	ribosomal protein S13	0.560
CUL2	cullin 2	0.559
NDUFA2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa	0.559
MAPT	microtubule-associated protein tau	0.557
FYN	FYN oncogene related to SRC, FGR, YES	0.553
TARDBP	TAR DNA binding protein	0.551
SKP2	S-phase kinase-associated protein 2 (p45)	0.547
FBXW11	F-box and WD repeat domain containing 11	0.546	Worm
NDUFS1	NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)	0.543	Worm
ATP5C1	ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1	0.543
RPS7	ribosomal protein S7	0.540
EXOSC2	exosome component 2	0.539
DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	0.538
AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1	0.538
TCP1	t-complex 1	0.537
UBC	ubiquitin C	0.537
EP300	E1A binding protein p300	0.537	Worm
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.536
NDUFS7	NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase)	0.535
SMAD4	SMAD family member 4	0.533
ATF2	activating transcription factor 2	0.533
POMP	proteasome maturation protein	0.530
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.530
MED25	mediator complex subunit 25	0.530
DHCR7	7-dehydrocholesterol reductase	0.529
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.526
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.525
COX6C	cytochrome c oxidase subunit VIc	0.524
RRAGC	Ras-related GTP binding C	0.523	Worm
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.522
EIF2C4	eukaryotic translation initiation factor 2C, 4	0.519
RPS2	ribosomal protein S2	0.518
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.515
PCBP2	poly(rC) binding protein 2	0.513
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.512
TKT	transketolase	0.512	Worm
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.510
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.509	Worm
SUCLA2	succinate-CoA ligase, ADP-forming, beta subunit	0.508
NDUFA6	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6, 14kDa	0.507	Worm
CAND1	cullin-associated and neddylation-dissociated 1	0.506
EZR	ezrin	0.505	Worm
NDUFB1	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa	0.504
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.502
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	0.502
HSPB8	heat shock 22kDa protein 8	0.500	Fly
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.498
SRSF3	serine/arginine-rich splicing factor 3	0.498
ATP5A1	ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle	0.496	Worm
ICT1	immature colon carcinoma transcript 1	0.492
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.490
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.488
HIPK3	homeodomain interacting protein kinase 3	0.487	Worm
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.487
GEMIN4	gem (nuclear organelle) associated protein 4	0.484
EEF2K	eukaryotic elongation factor-2 kinase	0.480
HSPH1	heat shock 105kDa/110kDa protein 1	0.476	Worm
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.473
DECR1	2,4-dienoyl CoA reductase 1, mitochondrial	0.471
COX8A	cytochrome c oxidase subunit VIIIA (ubiquitous)	0.471
DAXX	death-domain associated protein	0.469
RPS20	ribosomal protein S20	0.468
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.466
RPS27	ribosomal protein S27	0.463	Worm
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.462	Worm
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	0.461
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.460
RPS24	ribosomal protein S24	0.459
ATG5	ATG5 autophagy related 5 homolog (S. cerevisiae)	0.458
SFPQ	splicing factor proline/glutamine-rich	0.456
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.456
ZFX	zinc finger protein, X-linked	0.455
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.451
RPL11	ribosomal protein L11	0.450
EPAS1	endothelial PAS domain protein 1	0.449	Worm
FH	fumarate hydratase	0.445
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.444	Worm
RANBP3	RAN binding protein 3	0.443
TDG	thymine-DNA glycosylase	0.443
RANBP9	RAN binding protein 9	0.443	Worm
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.441
VDAC3	voltage-dependent anion channel 3	0.436
NDUFA9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	0.436	Worm
GAB2	GRB2-associated binding protein 2	0.435
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.434
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.432	Worm
EIF5	eukaryotic translation initiation factor 5	0.431
NUDT21	nudix (nucleoside diphosphate linked moiety X)-type motif 21	0.430
ETFA	electron-transfer-flavoprotein, alpha polypeptide	0.429
UQCRQ	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa	0.428
PPP6C	protein phosphatase 6, catalytic subunit	0.428
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.427
IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	0.426
PDHB	pyruvate dehydrogenase (lipoamide) beta	0.422	Worm
NUP93	nucleoporin 93kDa	0.417
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.414
RICTOR	RPTOR independent companion of MTOR, complex 2	0.413	Worm
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.413
TGFBR1	transforming growth factor, beta receptor 1	0.413	Fly
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.413
VDAC1	voltage-dependent anion channel 1	0.411
SPOP	speckle-type POZ protein	0.410
MAP2K2	mitogen-activated protein kinase kinase 2	0.409	Worm
HSPB2	heat shock 27kDa protein 2	0.409	Fly
MRPL23	mitochondrial ribosomal protein L23	0.409
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.407	Worm
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.405
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.403
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.401
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.399
PRMT1	protein arginine methyltransferase 1	0.398
GABARAP	GABA(A) receptor-associated protein	0.398	Worm
PRDX2	peroxiredoxin 2	0.395	Worm
ETF1	eukaryotic translation termination factor 1	0.390
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.390	Worm
MAPK6	mitogen-activated protein kinase 6	0.390
RPS3A	ribosomal protein S3A	0.390
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.389
KAT2B	K(lysine) acetyltransferase 2B	0.389
SLC25A5	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5	0.388	Worm Fly
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.388
MED15	mediator complex subunit 15	0.385
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.385
NDUFC1	NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa	0.385
DLD	dihydrolipoamide dehydrogenase	0.385	Worm
ENO1	enolase 1, (alpha)	0.384	Worm
EIF3CL	eukaryotic translation initiation factor 3, subunit C-like	0.383
TNRC6A	trinucleotide repeat containing 6A	0.382
MCM7	minichromosome maintenance complex component 7	0.382
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.382
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	0.380
MYH9	myosin, heavy chain 9, non-muscle	0.379
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.378
RPS4X	ribosomal protein S4, X-linked	0.377
NDUFA1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa	0.376
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.375
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.375	Worm
CANX	calnexin	0.375
TBC1D10A	TBC1 domain family, member 10A	0.374
RB1	retinoblastoma 1	0.373
RPS10	ribosomal protein S10	0.373	Worm
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.372
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.371	Worm
RPS5	ribosomal protein S5	0.370	Worm
UBE3A	ubiquitin protein ligase E3A	0.370
CCL3	chemokine (C-C motif) ligand 3	0.369
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.368
BLNK	B-cell linker	0.368
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.367
INSR	insulin receptor	0.367	Worm Fly
MRPS28	mitochondrial ribosomal protein S28	0.365
PRDX3	peroxiredoxin 3	0.364
SEH1L	SEH1-like (S. cerevisiae)	0.363
FXR1	fragile X mental retardation, autosomal homolog 1	0.360
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.359	Worm
ORC1	origin recognition complex, subunit 1	0.358
PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1	0.356	Worm
PTBP1	polypyrimidine tract binding protein 1	0.355
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.354	Worm
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.353
ATP5J2	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2	0.352
APP	amyloid beta (A4) precursor protein	0.352
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.350	Fly
RPL15	ribosomal protein L15	0.350
RPS23	ribosomal protein S23	0.350	Worm
RPS6	ribosomal protein S6	0.349	Worm
DIS3	DIS3 mitotic control homolog (S. cerevisiae)	0.349
SCD	stearoyl-CoA desaturase (delta-9-desaturase)	0.349	Worm
OPA1	optic atrophy 1 (autosomal dominant)	0.342
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.342
MDH2	malate dehydrogenase 2, NAD (mitochondrial)	0.341	Worm
MTIF2	mitochondrial translational initiation factor 2	0.341
RPL18A	ribosomal protein L18a	0.340
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.340
DUSP1	dual specificity phosphatase 1	0.338
RPS15A	ribosomal protein S15a	0.338	Worm
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.338	Worm
GAB1	GRB2-associated binding protein 1	0.337
NUP43	nucleoporin 43kDa	0.336
SH3KBP1	SH3-domain kinase binding protein 1	0.334
NOTCH3	notch 3	0.333	Fly
ALDOA	aldolase A, fructose-bisphosphate	0.333
TSC2	tuberous sclerosis 2	0.332	Fly
ADRM1	adhesion regulating molecule 1	0.331
CAT	catalase	0.331	Worm
SOD1	superoxide dismutase 1, soluble	0.331	Fly
COX6B1	cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)	0.330	Worm
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.330
RPS17	ribosomal protein S17	0.329
CTSA	cathepsin A	0.328
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.327
CHUK	conserved helix-loop-helix ubiquitous kinase	0.325
ATP5D	ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit	0.325
UQCR11	ubiquinol-cytochrome c reductase, complex III subunit XI	0.324
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.324
ZYX	zyxin	0.322
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.322	Fly
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.322
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.322
COX7C	cytochrome c oxidase subunit VIIc	0.321	Worm
NUP107	nucleoporin 107kDa	0.321
TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	0.321
SREBF2	sterol regulatory element binding transcription factor 2	0.320	Worm
CDK11B	cyclin-dependent kinase 11B	0.319
TGFB1	transforming growth factor, beta 1	0.318	Fly
NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	0.317
UBQLN1	ubiquilin 1	0.317	Worm
CYC1	cytochrome c-1	0.317	Worm
PPP5C	protein phosphatase 5, catalytic subunit	0.317
CSNK1D	casein kinase 1, delta	0.316
CPNE6	copine VI (neuronal)	0.316
TUFM	Tu translation elongation factor, mitochondrial	0.316	Worm
C14orf2	chromosome 14 open reading frame 2	0.315
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.314
RPL10A	ribosomal protein L10a	0.313
FOXO3	forkhead box O3	0.312	Fly
BAD	BCL2-associated agonist of cell death	0.312
MRPL48	mitochondrial ribosomal protein L48	0.312
NDUFA13	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13	0.311
FADS2	fatty acid desaturase 2	0.310
CNOT8	CCR4-NOT transcription complex, subunit 8	0.310
SKP1	S-phase kinase-associated protein 1	0.308	Worm
ATP5H	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit d	0.308	Worm
NDUFS6	NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase)	0.307	Mouse
EPOR	erythropoietin receptor	0.306
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.306
CPSF6	cleavage and polyadenylation specific factor 6, 68kDa	0.306
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.301
ATP5F1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1	0.300	Worm
PRDX1	peroxiredoxin 1	0.300	Worm
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.300	Worm
RBM25	RNA binding motif protein 25	0.299
MTHFD2	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase	0.298
CDK9	cyclin-dependent kinase 9	0.297
EIF5B	eukaryotic translation initiation factor 5B	0.295
RUNX1	runt-related transcription factor 1	0.295
GPI	glucose-6-phosphate isomerase	0.294	Worm
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.293
PML	promyelocytic leukemia	0.292
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.292
EXOSC7	exosome component 7	0.292
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.291
NDUFS4	NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)	0.291
PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	0.291	Worm
ACAT1	acetyl-CoA acetyltransferase 1	0.291
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.290
NLRC4	NLR family, CARD domain containing 4	0.290
CYTH1	cytohesin 1	0.286
RPS9	ribosomal protein S9	0.285
THOP1	thimet oligopeptidase 1	0.285
EIF3J	eukaryotic translation initiation factor 3, subunit J	0.285
CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	0.285	Worm
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.284
FUS	fused in sarcoma	0.284
VHL	von Hippel-Lindau tumor suppressor	0.283	Worm
IPO8	importin 8	0.282
PHB2	prohibitin 2	0.282	Worm
ILF3	interleukin enhancer binding factor 3, 90kDa	0.281
PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	0.281
PARP1	poly (ADP-ribose) polymerase 1	0.281
MEIS2	Meis homeobox 2	0.279	Worm
RPS12	ribosomal protein S12	0.279
HCCS	holocytochrome c synthase	0.278	Worm
EIF4E	eukaryotic translation initiation factor 4E	0.278	Worm
RAB1A	RAB1A, member RAS oncogene family	0.277
MEN1	multiple endocrine neoplasia I	0.277
LARP4	La ribonucleoprotein domain family, member 4	0.275
CCL14	chemokine (C-C motif) ligand 14	0.273
EEF2	eukaryotic translation elongation factor 2	0.273	Worm
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.273
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.272	Worm
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.272
NUP160	nucleoporin 160kDa	0.272
NCOA6	nuclear receptor coactivator 6	0.271
MBNL1	muscleblind-like (Drosophila)	0.271
NCOR2	nuclear receptor corepressor 2	0.271
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.269	Worm
STIP1	stress-induced-phosphoprotein 1	0.269
SH3RF1	SH3 domain containing ring finger 1	0.268	Fly
MAP1B	microtubule-associated protein 1B	0.268
TNRC6B	trinucleotide repeat containing 6B	0.266
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.265
PICALM	phosphatidylinositol binding clathrin assembly protein	0.265
MRPL4	mitochondrial ribosomal protein L4	0.264
TRA2B	transformer 2 beta homolog (Drosophila)	0.263
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.263
USP9X	ubiquitin specific peptidase 9, X-linked	0.260
BCOR	BCL6 corepressor	0.260
DHX36	DEAH (Asp-Glu-Ala-His) box polypeptide 36	0.259
HCFC1	host cell factor C1 (VP16-accessory protein)	0.259	Worm
IQGAP1	IQ motif containing GTPase activating protein 1	0.259
KHSRP	KH-type splicing regulatory protein	0.258
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.258
GSK3B	glycogen synthase kinase 3 beta	0.257
EIF4A3	eukaryotic translation initiation factor 4A3	0.257
SERBP1	SERPINE1 mRNA binding protein 1	0.257
AFG3L2	AFG3 ATPase family gene 3-like 2 (S. cerevisiae)	0.255	Worm
SREBF1	sterol regulatory element binding transcription factor 1	0.255	Worm
TIMM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	0.255
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.255
TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)	0.254
DIDO1	death inducer-obliterator 1	0.254
VAV1	vav 1 guanine nucleotide exchange factor	0.253
RPLP0	ribosomal protein, large, P0	0.253
SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	0.253
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.252
STRAP	serine/threonine kinase receptor associated protein	0.252
EGLN3	egl nine homolog 3 (C. elegans)	0.252
VARS	valyl-tRNA synthetase	0.250
NAGK	N-acetylglucosamine kinase	0.249
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.249
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.249	Worm Fly
CSNK1G2	casein kinase 1, gamma 2	0.249
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.248
IER3	immediate early response 3	0.247
BAG1	BCL2-associated athanogene	0.246
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.246
HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	0.245	Fly
CNOT2	CCR4-NOT transcription complex, subunit 2	0.244
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.242
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.241
NDUFB4	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa	0.241
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.241
NDUFB8	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa	0.241
FEN1	flap structure-specific endonuclease 1	0.240
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.240
TAGLN2	transgelin 2	0.239
LUC7L2	LUC7-like 2 (S. cerevisiae)	0.239
GATAD2B	GATA zinc finger domain containing 2B	0.239
EXOSC4	exosome component 4	0.239
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.238
SLC25A6	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6	0.238	Worm
IRF2	interferon regulatory factor 2	0.237
EZH2	enhancer of zeste homolog 2 (Drosophila)	0.236	Worm
RAD23A	RAD23 homolog A (S. cerevisiae)	0.236
LAMB2	laminin, beta 2 (laminin S)	0.236
CUL4A	cullin 4A	0.235
PSEN1	presenilin 1	0.235
RALBP1	ralA binding protein 1	0.235
RIPK2	receptor-interacting serine-threonine kinase 2	0.235
SMAD7	SMAD family member 7	0.235
USPL1	ubiquitin specific peptidase like 1	0.235
SAMM50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.235
TPI1	triosephosphate isomerase 1	0.234	Worm Fly
ACTB	actin, beta	0.234
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.233
EXOSC9	exosome component 9	0.233
AMD1	adenosylmethionine decarboxylase 1	0.233
ANAPC7	anaphase promoting complex subunit 7	0.232
RANBP2	RAN binding protein 2	0.232
CUL3	cullin 3	0.232	Worm
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.231	Worm
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.231
RBBP4	retinoblastoma binding protein 4	0.230
PRKCZ	protein kinase C, zeta	0.229
PARK7	Parkinson disease (autosomal recessive, early onset) 7	0.229
VASP	vasodilator-stimulated phosphoprotein	0.228
GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase	0.228
RPL31	ribosomal protein L31	0.227
TK1	thymidine kinase 1, soluble	0.227
BCR	breakpoint cluster region	0.227
CAPNS1	calpain, small subunit 1	0.226
HNRPDL	heterogeneous nuclear ribonucleoprotein D-like	0.226
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.226
SENP1	SUMO1/sentrin specific peptidase 1	0.226	Worm
MRPL19	mitochondrial ribosomal protein L19	0.225
LIG1	ligase I, DNA, ATP-dependent	0.225
TAF5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	0.224
RPL35	ribosomal protein L35	0.224
STARD7	StAR-related lipid transfer (START) domain containing 7	0.223
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	0.223
RPS27A	ribosomal protein S27a	0.222
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.222
NCOR1	nuclear receptor corepressor 1	0.222
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.222
ATF3	activating transcription factor 3	0.222
NDRG1	N-myc downstream regulated 1	0.222
CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.221
MAP2K3	mitogen-activated protein kinase kinase 3	0.221
RPS25	ribosomal protein S25	0.221
NHP2L1	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	0.221
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.220
OCRL	oculocerebrorenal syndrome of Lowe	0.219
RAB21	RAB21, member RAS oncogene family	0.218
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.217	Worm
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.217
NPC2	Niemann-Pick disease, type C2	0.216
DIS3L	DIS3 mitotic control homolog (S. cerevisiae)-like	0.216
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.215
TP73	tumor protein p73	0.215	Worm
DLG1	discs, large homolog 1 (Drosophila)	0.215
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.215
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	0.214
MRPL47	mitochondrial ribosomal protein L47	0.214	Worm
CFL1	cofilin 1 (non-muscle)	0.214
SP100	SP100 nuclear antigen	0.213
SSRP1	structure specific recognition protein 1	0.213
SUCLG1	succinate-CoA ligase, alpha subunit	0.212
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.212
RAB2A	RAB2A, member RAS oncogene family	0.212
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.212
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.210
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.210
PABPN1	poly(A) binding protein, nuclear 1	0.209
SNW1	SNW domain containing 1	0.209
MRPS11	mitochondrial ribosomal protein S11	0.207
PCBP1	poly(rC) binding protein 1	0.207
TRADD	TNFRSF1A-associated via death domain	0.207
EED	embryonic ectoderm development	0.206
DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta	0.206
ATR	ataxia telangiectasia and Rad3 related	0.206
SSB	Sjogren syndrome antigen B (autoantigen La)	0.206
TPBG	trophoblast glycoprotein	0.206
SPRY4	sprouty homolog 4 (Drosophila)	0.206
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.205
EIF3I	eukaryotic translation initiation factor 3, subunit I	0.204
SMS	spermine synthase	0.204
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.203
RAB4A	RAB4A, member RAS oncogene family	0.203
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.203
NUMB	numb homolog (Drosophila)	0.202
PA2G4	proliferation-associated 2G4, 38kDa	0.202
RPL19	ribosomal protein L19	0.202	Worm
MRPL18	mitochondrial ribosomal protein L18	0.201
SATB2	SATB homeobox 2	0.200
FKBP5	FK506 binding protein 5	0.200
MRPS16	mitochondrial ribosomal protein S16	0.200
CSNK1A1	casein kinase 1, alpha 1	0.200
CSTB	cystatin B (stefin B)	0.199
ZNF746	zinc finger protein 746	0.199
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.199
CAB39	calcium binding protein 39	0.198
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.198	Worm Fly
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.197
HDAC4	histone deacetylase 4	0.197
FBXW2	F-box and WD repeat domain containing 2	0.197
CSE1L	CSE1 chromosome segregation 1-like (yeast)	0.197
EWSR1	Ewing sarcoma breakpoint region 1	0.197
MYO10	myosin X	0.197
MAPKAPK5	mitogen-activated protein kinase-activated protein kinase 5	0.197
IRS2	insulin receptor substrate 2	0.196	Fly
TBK1	TANK-binding kinase 1	0.196
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.196
ATP6V1E1	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1	0.196
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.196
CUL1	cullin 1	0.196	Worm
TBC1D17	TBC1 domain family, member 17	0.196
UBQLN4	ubiquilin 4	0.195	Worm
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.195
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.195
DAZAP1	DAZ associated protein 1	0.195
DDX1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 1	0.195
CHMP2A	chromatin modifying protein 2A	0.195
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.194
PHB	prohibitin	0.194
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.194
PRKCA	protein kinase C, alpha	0.194
MCM5	minichromosome maintenance complex component 5	0.194
PNPT1	polyribonucleotide nucleotidyltransferase 1	0.193
ARNT	aryl hydrocarbon receptor nuclear translocator	0.193
SCHIP1	schwannomin interacting protein 1	0.193
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.193
VRK2	vaccinia related kinase 2	0.193	Worm
PLSCR1	phospholipid scramblase 1	0.192
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.192
LAMB1	laminin, beta 1	0.192
MARK3	MAP/microtubule affinity-regulating kinase 3	0.192
LIMD1	LIM domains containing 1	0.191
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.191
NOLC1	nucleolar and coiled-body phosphoprotein 1	0.191
E2F3	E2F transcription factor 3	0.190
MARK2	MAP/microtubule affinity-regulating kinase 2	0.190
PTP4A1	protein tyrosine phosphatase type IVA, member 1	0.190
GRB2	growth factor receptor-bound protein 2	0.190	Worm
FAM46A	family with sequence similarity 46, member A	0.189
ZNF148	zinc finger protein 148	0.189
BSG	basigin (Ok blood group)	0.189
PRDX6	peroxiredoxin 6	0.189
WTAP	Wilms tumor 1 associated protein	0.189
FAM118B	family with sequence similarity 118, member B	0.189
C19orf6	chromosome 19 open reading frame 6	0.189
CD320	CD320 molecule	0.189
FBXO11	F-box protein 11	0.188
PCCB	propionyl CoA carboxylase, beta polypeptide	0.188
ETFB	electron-transfer-flavoprotein, beta polypeptide	0.188
EIF3G	eukaryotic translation initiation factor 3, subunit G	0.188
MDH1	malate dehydrogenase 1, NAD (soluble)	0.187
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.187
FDPS	farnesyl diphosphate synthase	0.187
ARID1A	AT rich interactive domain 1A (SWI-like)	0.187
DDX56	DEAD (Asp-Glu-Ala-Asp) box polypeptide 56	0.187
FOXO1	forkhead box O1	0.186	Worm Fly
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.186
RPL21	ribosomal protein L21	0.186
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.186
MTCH2	mitochondrial carrier homolog 2 (C. elegans)	0.186	Worm
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.186
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.185
HBXIP	hepatitis B virus x interacting protein	0.185
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.185
GLUD1	glutamate dehydrogenase 1	0.185
EXOSC1	exosome component 1	0.184
EIF4B	eukaryotic translation initiation factor 4B	0.183
RFWD2	ring finger and WD repeat domain 2	0.183
RPS19	ribosomal protein S19	0.183
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.182
RPL5	ribosomal protein L5	0.182
NDUFA12	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12	0.182
RPL24	ribosomal protein L24	0.182
SLMAP	sarcolemma associated protein	0.182
SF1	splicing factor 1	0.182
NSUN2	NOP2/Sun domain family, member 2	0.181
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.181
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.181
AMOTL2	angiomotin like 2	0.181
PUF60	poly-U binding splicing factor 60KDa	0.180
UFM1	ubiquitin-fold modifier 1	0.180
C12orf4	chromosome 12 open reading frame 4	0.180
PDPK1	3-phosphoinositide dependent protein kinase-1	0.180
PRKCB	protein kinase C, beta	0.180
RBL2	retinoblastoma-like 2 (p130)	0.180
PTN	pleiotrophin	0.180
DOCK8	dedicator of cytokinesis 8	0.179
PRDX5	peroxiredoxin 5	0.179	Fly
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.179
RPL23A	ribosomal protein L23a	0.179
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.179
MAN2B1	mannosidase, alpha, class 2B, member 1	0.179
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.179
CD44	CD44 molecule (Indian blood group)	0.179
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.178
RIPK3	receptor-interacting serine-threonine kinase 3	0.178
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.178
CDK5RAP1	CDK5 regulatory subunit associated protein 1	0.177
ZNHIT6	zinc finger, HIT-type containing 6	0.177
PEA15	phosphoprotein enriched in astrocytes 15	0.176
QKI	quaking homolog, KH domain RNA binding (mouse)	0.176	Worm
MRPL11	mitochondrial ribosomal protein L11	0.176
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.175	Worm
DLL1	delta-like 1 (Drosophila)	0.175
COX7A2L	cytochrome c oxidase subunit VIIa polypeptide 2 like	0.175
DAPK1	death-associated protein kinase 1	0.175
SDCBP	syndecan binding protein (syntenin)	0.175
RPL29	ribosomal protein L29	0.174
ESR1	estrogen receptor 1	0.174
MRPS35	mitochondrial ribosomal protein S35	0.174
CYCS	cytochrome c, somatic	0.174	Worm
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.174
ACACA	acetyl-CoA carboxylase alpha	0.173	Worm
STK38L	serine/threonine kinase 38 like	0.173
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.173
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.172
TCOF1	Treacher Collins-Franceschetti syndrome 1	0.172
MRPL1	mitochondrial ribosomal protein L1	0.172	Worm
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.172	Worm
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.172	Worm
SIAH2	seven in absentia homolog 2 (Drosophila)	0.172
C17orf85	chromosome 17 open reading frame 85	0.171
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.171
SCP2	sterol carrier protein 2	0.170
TUBB	tubulin, beta	0.170
VIM	vimentin	0.170