IMP: Integrative Multi-species Prediction

Homo sapiens

15 genes annotated in human

Multi-species View

histone h4 k5 acetylation

GO:0043981

The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "histone h4 k5 acetylation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "histone h4 k5 acetylation" (in gray)

Name	Description	Probability	Func Analog Organism
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.995
WDR5	WD repeat domain 5	0.986
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.874
RBBP5	retinoblastoma binding protein 5	0.657
HIST1H3B	histone cluster 1, H3b	0.543
TP53	tumor protein p53	0.307
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.294
MYST1	MYST histone acetyltransferase 1	0.204
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.197
C20orf20	chromosome 20 open reading frame 20	0.192
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.190
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.140
SETD1A	SET domain containing 1A	0.121
BARD1	BRCA1 associated RING domain 1	0.113
FXR2	fragile X mental retardation, autosomal homolog 2	0.104
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.101
KIAA1377	KIAA1377	0.094
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.082
MGEA5	meningioma expressed antigen 5 (hyaluronidase)	0.080
HCFC1	host cell factor C1 (VP16-accessory protein)	0.070
MYST2	MYST histone acetyltransferase 2	0.070
SMAD1	SMAD family member 1	0.058
MEN1	multiple endocrine neoplasia I	0.055
CHD8	chromodomain helicase DNA binding protein 8	0.055
MED15	mediator complex subunit 15	0.054
ING5	inhibitor of growth family, member 5	0.052	Human
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.050
INO80	INO80 homolog (S. cerevisiae)	0.048
SNAPIN	SNAP-associated protein	0.048
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.041
MEST	mesoderm specific transcript homolog (mouse)	0.038
DAXX	death-domain associated protein	0.038
CREBBP	CREB binding protein	0.036
TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	0.030
DMAP1	DNA methyltransferase 1 associated protein 1	0.030
CEP70	centrosomal protein 70kDa	0.029
CCDC101	coiled-coil domain containing 101	0.029
CALCOCO2	calcium binding and coiled-coil domain 2	0.029
USP42	ubiquitin specific peptidase 42	0.028
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.028
PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)	0.027
THAP11	THAP domain containing 11	0.027
IP6K2	inositol hexakisphosphate kinase 2	0.026
UBE3A	ubiquitin protein ligase E3A	0.026
MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	0.026
RBM23	RNA binding motif protein 23	0.025
CXXC1	CXXC finger protein 1	0.024
ZCCHC8	zinc finger, CCHC domain containing 8	0.024
INO80E	INO80 complex subunit E	0.024
WDR82	WD repeat domain 82	0.024
NQO1	NAD(P)H dehydrogenase, quinone 1	0.023
PAPD7	PAP associated domain containing 7	0.022
TP53BP1	tumor protein p53 binding protein 1	0.021
ARIH2	ariadne homolog 2 (Drosophila)	0.020
SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	0.020
ZNF420	zinc finger protein 420	0.018
ZBTB8A	zinc finger and BTB domain containing 8A	0.018
PHC2	polyhomeotic homolog 2 (Drosophila)	0.018
CDK11B	cyclin-dependent kinase 11B	0.018
AR	androgen receptor	0.017
MAD2L1BP	MAD2L1 binding protein	0.017
CREBZF	CREB/ATF bZIP transcription factor	0.017
DPCD	deleted in primary ciliary dyskinesia homolog (mouse)	0.016
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.016
PAXIP1	PAX interacting (with transcription-activation domain) protein 1	0.016
TADA3	transcriptional adaptor 3	0.016
CCDC14	coiled-coil domain containing 14	0.016
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.016
ZBTB17	zinc finger and BTB domain containing 17	0.015
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.015
MBIP	MAP3K12 binding inhibitory protein 1	0.015
MKRN1	makorin ring finger protein 1	0.015
MSL2	male-specific lethal 2 homolog (Drosophila)	0.015
EP300	E1A binding protein p300	0.015
SAP30	Sin3A-associated protein, 30kDa	0.015
FBXL15	F-box and leucine-rich repeat protein 15	0.014
KIAA1267	KIAA1267	0.014
PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta	0.014
YTHDF1	YTH domain family, member 1	0.014
HIST2H3C	histone cluster 2, H3c	0.014
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.014
POLB	polymerase (DNA directed), beta	0.014
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.013
C19orf50	chromosome 19 open reading frame 50	0.013
SEPT8	septin 8	0.013
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.013
KAT5	K(lysine) acetyltransferase 5	0.013	Human
ING4	inhibitor of growth family, member 4	0.013
KDM2A	lysine (K)-specific demethylase 2A	0.012
TRAF4	TNF receptor-associated factor 4	0.012
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.012
TRRAP	transformation/transcription domain-associated protein	0.012
TNRC6B	trinucleotide repeat containing 6B	0.012
SETD1B	SET domain containing 1B	0.012
HIST1H4F	histone cluster 1, H4f	0.012
ASXL1	additional sex combs like 1 (Drosophila)	0.012
RFWD2	ring finger and WD repeat domain 2	0.012
ING2	inhibitor of growth family, member 2	0.012	Human
VEZT	vezatin, adherens junctions transmembrane protein	0.011
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.011
KIAA0240	KIAA0240	0.011
ANKRD13D	ankyrin repeat domain 13 family, member D	0.011
ATM	ataxia telangiectasia mutated	0.011
ZNF512B	zinc finger protein 512B	0.011
GKAP1	G kinase anchoring protein 1	0.010
SCAMP1	secretory carrier membrane protein 1	0.010