Process View
An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "erk1 and erk2 cascade"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 1.000 | Fly | |
EGFR | epidermal growth factor receptor | 1.000 | ||
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 1.000 | Fly | |
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 1.000 | ||
MAPK14 | mitogen-activated protein kinase 14 | 1.000 | ||
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 1.000 | ||
MAPK1 | mitogen-activated protein kinase 1 | 1.000 | ||
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 1.000 | ||
FGFR2 | fibroblast growth factor receptor 2 | 1.000 | Human Mouse | |
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.999 | Human Fly | |
DUSP1 | dual specificity phosphatase 1 | 0.999 | Human Rat | |
ERBB2 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian) | 0.999 | ||
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.998 | ||
MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.997 | Fly | |
CRK | v-crk sarcoma virus CT10 oncogene homolog (avian) | 0.996 | ||
YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide | 0.995 | Fly | |
FGFR1 | fibroblast growth factor receptor 1 | 0.995 | Human | |
VEGFA | vascular endothelial growth factor A | 0.993 | ||
SFN | stratifin | 0.992 | Fly | |
IL8 | interleukin 8 | 0.991 | ||
FYN | FYN oncogene related to SRC, FGR, YES | 0.989 | ||
CCR5 | chemokine (C-C motif) receptor 5 | 0.986 | Human | |
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.982 | Human | |
TRAF1 | TNF receptor-associated factor 1 | 0.980 | ||
FAS | Fas (TNF receptor superfamily, member 6) | 0.980 | ||
TEK | TEK tyrosine kinase, endothelial | 0.980 | ||
MAPK3 | mitogen-activated protein kinase 3 | 0.971 | ||
GSK3B | glycogen synthase kinase 3 beta | 0.965 | ||
MLLT4 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 | 0.954 | ||
FGF1 | fibroblast growth factor 1 (acidic) | 0.951 | Human | |
SH3KBP1 | SH3-domain kinase binding protein 1 | 0.951 | ||
FN1 | fibronectin 1 | 0.951 | ||
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.948 | ||
IGF1R | insulin-like growth factor 1 receptor | 0.931 | ||
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.903 | ||
CCL2 | chemokine (C-C motif) ligand 2 | 0.895 | Human | |
GUCY2C | guanylate cyclase 2C (heat stable enterotoxin receptor) | 0.894 | ||
IL1B | interleukin 1, beta | 0.894 | Rat | |
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.885 | ||
PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.879 | ||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.863 | ||
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.853 | Mouse Rat | |
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.850 | Mouse | |
BCR | breakpoint cluster region | 0.845 | ||
C1QA | complement component 1, q subcomponent, A chain | 0.841 | Human | |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.838 | ||
BIRC3 | baculoviral IAP repeat containing 3 | 0.828 | ||
PDGFB | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | 0.823 | ||
AXL | AXL receptor tyrosine kinase | 0.783 | ||
SOS1 | son of sevenless homolog 1 (Drosophila) | 0.782 | ||
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.779 | ||
PTPN6 | protein tyrosine phosphatase, non-receptor type 6 | 0.778 | ||
MAGOH | mago-nashi homolog, proliferation-associated (Drosophila) | 0.775 | Fly | |
IL6 | interleukin 6 (interferon, beta 2) | 0.765 | ||
CCR7 | chemokine (C-C motif) receptor 7 | 0.749 | Human | |
TNF | tumor necrosis factor | 0.747 | ||
YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 0.747 | Fly | |
MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.742 | ||
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.739 | Mouse | |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.737 | ||
LCP2 | lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa) | 0.735 | ||
CCL4 | chemokine (C-C motif) ligand 4 | 0.732 | Human | |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.700 | ||
SPRR2A | small proline-rich protein 2A | 0.698 | ||
MPDZ | multiple PDZ domain protein | 0.692 | ||
TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.680 | ||
CSNK2B | casein kinase 2, beta polypeptide | 0.679 | ||
SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.664 | ||
FGA | fibrinogen alpha chain | 0.664 | ||
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.659 | Mouse | |
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.659 | ||
CCL5 | chemokine (C-C motif) ligand 5 | 0.655 | Human | |
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.654 | ||
PLAUR | plasminogen activator, urokinase receptor | 0.652 | ||
ESR1 | estrogen receptor 1 | 0.647 | Rat | |
FGB | fibrinogen beta chain | 0.637 | ||
WAS | Wiskott-Aldrich syndrome (eczema-thrombocytopenia) | 0.626 | ||
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.620 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.613 | ||
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.609 | ||
PECAM1 | platelet/endothelial cell adhesion molecule | 0.600 | ||
NRP1 | neuropilin 1 | 0.600 | Mouse | |
THBS1 | thrombospondin 1 | 0.589 | ||
BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.578 | ||
SMN1 | survival of motor neuron 1, telomeric | 0.565 | ||
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.565 | ||
KLF6 | Kruppel-like factor 6 | 0.542 | ||
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.532 | ||
LRRC7 | leucine rich repeat containing 7 | 0.531 | ||
ICAM1 | intercellular adhesion molecule 1 | 0.529 | ||
PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.526 | ||
CTGF | connective tissue growth factor | 0.525 | ||
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.523 | ||
CCL19 | chemokine (C-C motif) ligand 19 | 0.520 | ||
SLMAP | sarcolemma associated protein | 0.520 | ||
ZNF496 | zinc finger protein 496 | 0.519 | ||
CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.518 | ||
GAB1 | GRB2-associated binding protein 1 | 0.518 | ||
FLT1 | fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor) | 0.515 | Human | |
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.506 | ||
SNIP1 | Smad nuclear interacting protein 1 | 0.503 | ||
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.501 | ||
TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.501 | ||
SOCS3 | suppressor of cytokine signaling 3 | 0.483 | ||
IL2RB | interleukin 2 receptor, beta | 0.475 | ||
EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.474 | Fly | |
MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.474 | ||
PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | 0.474 | ||
PTPRR | protein tyrosine phosphatase, receptor type, R | 0.473 | ||
TRAF2 | TNF receptor-associated factor 2 | 0.472 | ||
ANGPT2 | angiopoietin 2 | 0.457 | Human | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.453 | Human | |
IFNG | interferon, gamma | 0.444 | ||
PTEN | phosphatase and tensin homolog | 0.434 | ||
RAP1A | RAP1A, member of RAS oncogene family | 0.433 | Mouse Rat | |
CCL8 | chemokine (C-C motif) ligand 8 | 0.429 | Human | |
CCL22 | chemokine (C-C motif) ligand 22 | 0.426 | Human | |
CD2 | CD2 molecule | 0.424 | ||
GHR | growth hormone receptor | 0.417 | ||
IER3 | immediate early response 3 | 0.413 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.402 | ||
LAIR1 | leukocyte-associated immunoglobulin-like receptor 1 | 0.401 | ||
DUSP7 | dual specificity phosphatase 7 | 0.399 | Human | |
CDH5 | cadherin 5, type 2 (vascular endothelium) | 0.397 | ||
LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.392 | ||
CCR4 | chemokine (C-C motif) receptor 4 | 0.391 | Human | |
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.391 | ||
CCR1 | chemokine (C-C motif) receptor 1 | 0.390 | ||
TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.388 | ||
SPRY2 | sprouty homolog 2 (Drosophila) | 0.385 | ||
MET | met proto-oncogene (hepatocyte growth factor receptor) | 0.382 | ||
PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.382 | ||
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.372 | ||
KDR | kinase insert domain receptor (a type III receptor tyrosine kinase) | 0.369 | ||
TGFA | transforming growth factor, alpha | 0.368 | ||
IL10 | interleukin 10 | 0.367 | ||
IRF4 | interferon regulatory factor 4 | 0.362 | ||
PPP1R9B | protein phosphatase 1, regulatory (inhibitor) subunit 9B | 0.356 | ||
CCL13 | chemokine (C-C motif) ligand 13 | 0.355 | Human | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.346 | ||
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.345 | ||
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.344 | ||
ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.341 | Human Fly | |
DUSP5 | dual specificity phosphatase 5 | 0.341 | Human | |
GRB10 | growth factor receptor-bound protein 10 | 0.340 | ||
C1S | complement component 1, s subcomponent | 0.334 | ||
CCL7 | chemokine (C-C motif) ligand 7 | 0.318 | Human | |
APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) | 0.318 | ||
MSN | moesin | 0.317 | ||
CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.315 | Human | |
CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.313 | Human | |
SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.312 | ||
PLCG1 | phospholipase C, gamma 1 | 0.312 | ||
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.310 | ||
CFLAR | CASP8 and FADD-like apoptosis regulator | 0.308 | ||
BMPR1A | bone morphogenetic protein receptor, type IA | 0.308 | ||
FGF7 | fibroblast growth factor 7 | 0.307 | Human | |
IGFBP3 | insulin-like growth factor binding protein 3 | 0.302 | ||
MAFF | v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) | 0.301 | ||
LAT | linker for activation of T cells | 0.296 | ||
PVRL3 | poliovirus receptor-related 3 | 0.294 | ||
STAT5A | signal transducer and activator of transcription 5A | 0.292 | ||
CCL3 | chemokine (C-C motif) ligand 3 | 0.290 | ||
TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.275 | Human | |
STRN | striatin, calmodulin binding protein | 0.272 | ||
RET | ret proto-oncogene | 0.271 | ||
CCL20 | chemokine (C-C motif) ligand 20 | 0.269 | Human | |
C1QC | complement component 1, q subcomponent, C chain | 0.266 | Human | |
BHLHE40 | basic helix-loop-helix family, member e40 | 0.261 | ||
CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.256 | ||
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.255 | Fly | |
CYR61 | cysteine-rich, angiogenic inducer, 61 | 0.250 | ||
SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1 | 0.248 | ||
MMP9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 0.248 | ||
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.247 | Human | |
BMPR1B | bone morphogenetic protein receptor, type IB | 0.246 | ||
TRADD | TNFRSF1A-associated via death domain | 0.246 | ||
SMAD2 | SMAD family member 2 | 0.245 | ||
YWHAH | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 0.245 | Fly | |
KLHL3 | kelch-like 3 (Drosophila) | 0.244 | ||
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.236 | ||
CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.236 | Human | |
CCR2 | chemokine (C-C motif) receptor 2 | 0.235 | Human | |
TICAM2 | toll-like receptor adaptor molecule 2 | 0.234 | ||
ARRB2 | arrestin, beta 2 | 0.234 | ||
FGG | fibrinogen gamma chain | 0.231 | ||
RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.227 | ||
HSPG2 | heparan sulfate proteoglycan 2 | 0.226 | ||
CD40LG | CD40 ligand | 0.223 | ||
PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.221 | ||
PRKCA | protein kinase C, alpha | 0.218 | ||
COTL1 | coactosin-like 1 (Dictyostelium) | 0.218 | ||
RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.217 | ||
ERBB4 | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 0.213 | ||
WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 | 0.212 | ||
PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | 0.211 | Human Mouse | |
CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.210 | ||
PEA15 | phosphoprotein enriched in astrocytes 15 | 0.207 | ||
MEOX2 | mesenchyme homeobox 2 | 0.207 | ||
MMP2 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 0.207 | ||
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.207 | ||
CRP | C-reactive protein, pentraxin-related | 0.203 | ||
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.202 | ||
YBX1 | Y box binding protein 1 | 0.202 | ||
PXN | paxillin | 0.202 | ||
MYO10 | myosin X | 0.202 | ||
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.197 | ||
C1QB | complement component 1, q subcomponent, B chain | 0.196 | Human | |
PTGIS | prostaglandin I2 (prostacyclin) synthase | 0.190 | ||
TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.190 | ||
EDN1 | endothelin 1 | 0.189 | ||
ARHGAP9 | Rho GTPase activating protein 9 | 0.187 | ||
APOA1 | apolipoprotein A-I | 0.185 | ||
TRAF5 | TNF receptor-associated factor 5 | 0.183 | ||
FBLN1 | fibulin 1 | 0.183 | ||
FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.181 | Human | |
CXCR2 | chemokine (C-X-C motif) receptor 2 | 0.181 | Human | |
SPRY4 | sprouty homolog 4 (Drosophila) | 0.178 | Human | |
DUSP6 | dual specificity phosphatase 6 | 0.178 | ||
IL7R | interleukin 7 receptor | 0.178 | ||
TNPO1 | transportin 1 | 0.176 | ||
CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.175 | ||
LYN | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 0.171 | ||
GAB2 | GRB2-associated binding protein 2 | 0.170 | ||
FGF10 | fibroblast growth factor 10 | 0.170 | ||
MARCO | macrophage receptor with collagenous structure | 0.169 | ||
TLR2 | toll-like receptor 2 | 0.168 | ||
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.167 | Rat | |
MBP | myelin basic protein | 0.167 | ||
FRS2 | fibroblast growth factor receptor substrate 2 | 0.165 | Mouse | |
ARRB1 | arrestin, beta 1 | 0.165 | ||
STC1 | stanniocalcin 1 | 0.165 | ||
HBEGF | heparin-binding EGF-like growth factor | 0.161 | ||
CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.161 | Human | |
SMAD3 | SMAD family member 3 | 0.161 | ||
NOXA1 | NADPH oxidase activator 1 | 0.158 | ||
FPR1 | formyl peptide receptor 1 | 0.158 | Human | |
CSF1 | colony stimulating factor 1 (macrophage) | 0.156 | ||
CD33 | CD33 molecule | 0.156 | ||
ABL2 | v-abl Abelson murine leukemia viral oncogene homolog 2 | 0.156 | Mouse | |
ITGB5 | integrin, beta 5 | 0.156 | ||
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.155 | ||
AQP9 | aquaporin 9 | 0.155 | ||
AHNAK | AHNAK nucleoprotein | 0.154 | ||
MEFV | Mediterranean fever | 0.152 | ||
ZFP36L1 | zinc finger protein 36, C3H type-like 1 | 0.151 | ||
PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.148 | ||
CHERP | calcium homeostasis endoplasmic reticulum protein | 0.148 | ||
MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.146 | ||
DPP4 | dipeptidyl-peptidase 4 | 0.145 | ||
YAP1 | Yes-associated protein 1 | 0.144 | ||
SRPK1 | SRSF protein kinase 1 | 0.143 | ||
MAP4K1 | mitogen-activated protein kinase kinase kinase kinase 1 | 0.143 | ||
ADAM15 | ADAM metallopeptidase domain 15 | 0.141 | ||
GFAP | glial fibrillary acidic protein | 0.141 | ||
U2AF1 | U2 small nuclear RNA auxiliary factor 1 | 0.140 | ||
ZNF746 | zinc finger protein 746 | 0.139 | ||
CCKBR | cholecystokinin B receptor | 0.139 | Rat | |
IL1RAP | interleukin 1 receptor accessory protein | 0.138 | ||
CSF2RB | colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) | 0.138 | ||
EPHA3 | EPH receptor A3 | 0.138 | Human | |
EPHA2 | EPH receptor A2 | 0.137 | ||
CAV2 | caveolin 2 | 0.136 | ||
TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.136 | Human | |
CD48 | CD48 molecule | 0.135 | ||
INSR | insulin receptor | 0.135 | ||
NRP2 | neuropilin 2 | 0.135 | ||
APC | adenomatous polyposis coli | 0.134 | ||
WASL | Wiskott-Aldrich syndrome-like | 0.133 | ||
BIRC2 | baculoviral IAP repeat containing 2 | 0.130 | ||
NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.130 | ||
IL1R1 | interleukin 1 receptor, type I | 0.130 | ||
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | 0.130 | ||
LY6G6F | lymphocyte antigen 6 complex, locus G6F | 0.129 | ||
INHBA | inhibin, beta A | 0.127 | ||
RIN1 | Ras and Rab interactor 1 | 0.127 | ||
FSTL1 | follistatin-like 1 | 0.127 | ||
CCL14 | chemokine (C-C motif) ligand 14 | 0.126 | Human | |
IL18RAP | interleukin 18 receptor accessory protein | 0.126 | ||
EFNA5 | ephrin-A5 | 0.125 | ||
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.125 | ||
ATP8 | ATP synthase F0 subunit 8 | 0.124 | ||
FGF8 | fibroblast growth factor 8 (androgen-induced) | 0.124 | ||
TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 | 0.123 | ||
MMP19 | matrix metallopeptidase 19 | 0.123 | ||
PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 | 0.120 | ||
TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.119 | Human | |
IL1RN | interleukin 1 receptor antagonist | 0.119 | ||
HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | 0.118 | ||
RGS1 | regulator of G-protein signaling 1 | 0.117 | ||
CYSLTR2 | cysteinyl leukotriene receptor 2 | 0.117 | Human Rat | |
CCR3 | chemokine (C-C motif) receptor 3 | 0.116 | Human Rat | |
RALGDS | ral guanine nucleotide dissociation stimulator | 0.115 | ||
GAST | gastrin | 0.114 | ||
RCC1 | regulator of chromosome condensation 1 | 0.114 | ||
RANBP3 | RAN binding protein 3 | 0.113 | ||
VSIG4 | V-set and immunoglobulin domain containing 4 | 0.112 | ||
LDB1 | LIM domain binding 1 | 0.112 | ||
SLAMF8 | SLAM family member 8 | 0.111 | ||
SOCS1 | suppressor of cytokine signaling 1 | 0.111 | ||
CXCR3 | chemokine (C-X-C motif) receptor 3 | 0.111 | Human | |
GRB7 | growth factor receptor-bound protein 7 | 0.110 | ||
HDAC7 | histone deacetylase 7 | 0.110 | ||
TGS1 | trimethylguanosine synthase 1 | 0.110 | ||
CD163 | CD163 molecule | 0.110 | ||
HLA-DMA | major histocompatibility complex, class II, DM alpha | 0.109 | ||
TAL1 | T-cell acute lymphocytic leukemia 1 | 0.109 | ||
TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.108 | Human | |
PDCD6IP | programmed cell death 6 interacting protein | 0.107 | ||
EFNA1 | ephrin-A1 | 0.107 | ||
IL1R2 | interleukin 1 receptor, type II | 0.107 | ||
ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.106 | ||
CCL11 | chemokine (C-C motif) ligand 11 | 0.106 | Human | |
IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.106 | ||
MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.106 | ||
PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.106 | ||
NGF | nerve growth factor (beta polypeptide) | 0.105 | ||
PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.105 | ||
RGS16 | regulator of G-protein signaling 16 | 0.105 | ||
HRAS | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 0.104 | ||
GRB2 | growth factor receptor-bound protein 2 | 0.104 | ||
PTPN7 | protein tyrosine phosphatase, non-receptor type 7 | 0.104 | Human Fly | |
IL16 | interleukin 16 (lymphocyte chemoattractant factor) | 0.104 | ||
SIGLEC7 | sialic acid binding Ig-like lectin 7 | 0.104 | ||
CNR2 | cannabinoid receptor 2 (macrophage) | 0.104 | ||
CORO1C | coronin, actin binding protein, 1C | 0.104 | ||
MAP2K3 | mitogen-activated protein kinase kinase 3 | 0.103 | ||
CCNE1 | cyclin E1 | 0.103 | ||
OXSR1 | oxidative-stress responsive 1 | 0.102 | ||
KRAS | v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog | 0.101 | Human | |
JAK2 | Janus kinase 2 | 0.101 | ||
SELE | selectin E | 0.100 | ||
ZFP36 | zinc finger protein 36, C3H type, homolog (mouse) | 0.100 | ||
C2 | complement component 2 | 0.100 | ||
PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) | 0.099 | ||
PTPRB | protein tyrosine phosphatase, receptor type, B | 0.099 | ||
SLC6A3 | solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 | 0.098 | ||
CHIT1 | chitinase 1 (chitotriosidase) | 0.098 | Human | |
G0S2 | G0/G1switch 2 | 0.098 | ||
TGFB2 | transforming growth factor, beta 2 | 0.097 | ||
SRPK2 | SRSF protein kinase 2 | 0.096 | ||
IL2RG | interleukin 2 receptor, gamma | 0.095 | ||
ABI1 | abl-interactor 1 | 0.095 | ||
PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.095 | ||
TREM1 | triggering receptor expressed on myeloid cells 1 | 0.095 | ||
RALBP1 | ralA binding protein 1 | 0.094 | ||
PDCD10 | programmed cell death 10 | 0.093 | ||
TNC | tenascin C | 0.092 | ||
PTPRC | protein tyrosine phosphatase, receptor type, C | 0.092 | ||
IL32 | interleukin 32 | 0.091 | ||
PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) | 0.091 | ||
TGFB3 | transforming growth factor, beta 3 | 0.091 | ||
NTF4 | neurotrophin 4 | 0.091 | ||
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.090 | ||
PEBP4 | phosphatidylethanolamine-binding protein 4 | 0.090 | ||
MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 0.090 | ||
RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | 0.089 | Human | |
DUSP3 | dual specificity phosphatase 3 | 0.089 | ||
MSR1 | macrophage scavenger receptor 1 | 0.089 | ||
CYTH4 | cytohesin 4 | 0.088 | ||
ADORA2A | adenosine A2a receptor | 0.088 | ||
AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.088 | Human | |
LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.088 | ||
MTPN | myotrophin | 0.087 | ||
TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.087 | ||
MED1 | mediator complex subunit 1 | 0.087 | ||
DARC | Duffy blood group, chemokine receptor | 0.087 | ||
IRS1 | insulin receptor substrate 1 | 0.087 | ||
FGF2 | fibroblast growth factor 2 (basic) | 0.087 | ||
NLRP3 | NLR family, pyrin domain containing 3 | 0.086 | ||
SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | 0.086 | ||
CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.085 | ||
WWOX | WW domain containing oxidoreductase | 0.084 | ||
GNAI3 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 | 0.084 | ||
HCK | hemopoietic cell kinase | 0.083 | ||
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.083 | ||
NOG | noggin | 0.083 | ||
TGM2 | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 0.083 | ||
SSTR3 | somatostatin receptor 3 | 0.083 | ||
CD34 | CD34 molecule | 0.082 | ||
ANGPT1 | angiopoietin 1 | 0.082 | ||
GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.082 | ||
CYSLTR1 | cysteinyl leukotriene receptor 1 | 0.082 | Human | |
JAG1 | jagged 1 | 0.082 | ||
MMP14 | matrix metallopeptidase 14 (membrane-inserted) | 0.082 | ||
CD2AP | CD2-associated protein | 0.081 | ||
MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.081 | ||
KSR1 | kinase suppressor of ras 1 | 0.081 | Human Fly | |
RASGRF1 | Ras protein-specific guanine nucleotide-releasing factor 1 | 0.081 | ||
GEM | GTP binding protein overexpressed in skeletal muscle | 0.080 | ||
SPP1 | secreted phosphoprotein 1 | 0.079 | ||
CTTNBP2NL | CTTNBP2 N-terminal like | 0.079 | ||
EBI3 | Epstein-Barr virus induced 3 | 0.079 | ||
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.079 | ||
MUC1 | mucin 1, cell surface associated | 0.078 | ||
BMP4 | bone morphogenetic protein 4 | 0.078 | Human Mouse Rat | |
SLCO2B1 | solute carrier organic anion transporter family, member 2B1 | 0.078 | ||
IGF2 | insulin-like growth factor 2 (somatomedin A) | 0.078 | ||
SLAMF7 | SLAM family member 7 | 0.078 | ||
NTRK1 | neurotrophic tyrosine kinase, receptor, type 1 | 0.077 | ||
NME2 | non-metastatic cells 2, protein (NM23B) expressed in | 0.077 | ||
FPR3 | formyl peptide receptor 3 | 0.077 | Human | |
MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.077 | ||
CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.076 | ||
DKK1 | dickkopf homolog 1 (Xenopus laevis) | 0.076 | ||
CCDC6 | coiled-coil domain containing 6 | 0.076 | ||
CIITA | class II, major histocompatibility complex, transactivator | 0.076 | ||
TBX21 | T-box 21 | 0.075 | ||
SASH3 | SAM and SH3 domain containing 3 | 0.075 | ||
VEGFC | vascular endothelial growth factor C | 0.075 | Human | |
HLA-DOA | major histocompatibility complex, class II, DO alpha | 0.075 | ||
GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.075 | ||
EPHA7 | EPH receptor A7 | 0.075 | ||
CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) | 0.074 | ||
C3 | complement component 3 | 0.074 | ||
ZNF71 | zinc finger protein 71 | 0.074 | ||
IL1A | interleukin 1, alpha | 0.073 | ||
STK4 | serine/threonine kinase 4 | 0.073 | ||
CDK12 | cyclin-dependent kinase 12 | 0.073 | Fly | |
CD80 | CD80 molecule | 0.073 | ||
OSMR | oncostatin M receptor | 0.073 | ||
MYD88 | myeloid differentiation primary response gene (88) | 0.073 | ||
FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) | 0.072 | ||
PEBP1 | phosphatidylethanolamine binding protein 1 | 0.072 | ||
TTR | transthyretin | 0.071 | ||
A2M | alpha-2-macroglobulin | 0.071 | ||
ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.071 | ||
IL4R | interleukin 4 receptor | 0.071 | ||
PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.070 | ||
ADM | adrenomedullin | 0.070 | ||
TM4SF1 | transmembrane 4 L six family member 1 | 0.070 | ||
LILRB5 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5 | 0.069 | ||
WFIKKN1 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1 | 0.069 | ||
DDR2 | discoidin domain receptor tyrosine kinase 2 | 0.068 | ||
FGR | Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog | 0.067 | ||
IGSF6 | immunoglobulin superfamily, member 6 | 0.067 | ||
TNFSF8 | tumor necrosis factor (ligand) superfamily, member 8 | 0.066 | ||
GSN | gelsolin | 0.066 | ||
FGFR3 | fibroblast growth factor receptor 3 | 0.066 | ||
GADD45B | growth arrest and DNA-damage-inducible, beta | 0.065 | ||
LARP7 | La ribonucleoprotein domain family, member 7 | 0.065 | ||
ACVRL1 | activin A receptor type II-like 1 | 0.065 | ||
PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | 0.065 | ||
NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | 0.065 | Human | |
WIPF1 | WAS/WASL interacting protein family, member 1 | 0.065 | ||
AXIN1 | axin 1 | 0.064 | ||
PLA2G2D | phospholipase A2, group IID | 0.064 | ||
ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | 0.064 | ||
FBN1 | fibrillin 1 | 0.064 | ||
PRRX1 | paired related homeobox 1 | 0.064 | ||
KLB | klotho beta | 0.063 | ||
PTGER3 | prostaglandin E receptor 3 (subtype EP3) | 0.063 | ||
DUSP4 | dual specificity phosphatase 4 | 0.063 | Human | |
AMOTL2 | angiomotin like 2 | 0.063 | ||
CMKLR1 | chemokine-like receptor 1 | 0.062 | Human | |
EMR1 | egf-like module containing, mucin-like, hormone receptor-like 1 | 0.062 | ||
FCGR3B | Fc fragment of IgG, low affinity IIIb, receptor (CD16b) | 0.062 | ||
PDGFA | platelet-derived growth factor alpha polypeptide | 0.062 | ||
WNT2 | wingless-type MMTV integration site family member 2 | 0.062 | ||
HS3ST2 | heparan sulfate (glucosamine) 3-O-sulfotransferase 2 | 0.062 | ||
MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.061 | ||
DUSP9 | dual specificity phosphatase 9 | 0.061 | Human | |
BIN2 | bridging integrator 2 | 0.061 | ||
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.061 | ||
CCK | cholecystokinin | 0.061 | ||
PAWR | PRKC, apoptosis, WT1, regulator | 0.061 | ||
MAPK10 | mitogen-activated protein kinase 10 | 0.061 | ||
HSD11B1 | hydroxysteroid (11-beta) dehydrogenase 1 | 0.061 | ||
C5AR1 | complement component 5a receptor 1 | 0.060 | ||
HTR4 | 5-hydroxytryptamine (serotonin) receptor 4 | 0.060 | Human | |
NNMT | nicotinamide N-methyltransferase | 0.060 | ||
PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.060 | ||
MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.060 | ||
S100A12 | S100 calcium binding protein A12 | 0.060 | ||
COL2A1 | collagen, type II, alpha 1 | 0.060 | ||
CD83 | CD83 molecule | 0.060 | ||
ILK | integrin-linked kinase | 0.059 | ||
TOM1L1 | target of myb1 (chicken)-like 1 | 0.059 | ||
SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.059 | ||
BCL3 | B-cell CLL/lymphoma 3 | 0.059 | ||
MAPRE2 | microtubule-associated protein, RP/EB family, member 2 | 0.059 | ||
SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.059 | Human Mouse | |
CD28 | CD28 molecule | 0.059 | ||
EPHB2 | EPH receptor B2 | 0.059 | Human | |
FCN2 | ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin) | 0.059 | Human | |
BCL2A1 | BCL2-related protein A1 | 0.059 | ||
FCER2 | Fc fragment of IgE, low affinity II, receptor for (CD23) | 0.058 | ||
RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.058 | ||
LDB2 | LIM domain binding 2 | 0.057 | ||
SELL | selectin L | 0.057 | ||
IL5RA | interleukin 5 receptor, alpha | 0.056 | ||
SH3RF1 | SH3 domain containing ring finger 1 | 0.056 | ||
IHH | Indian hedgehog | 0.056 | ||
NTN1 | netrin 1 | 0.056 | ||
TIE1 | tyrosine kinase with immunoglobulin-like and EGF-like domains 1 | 0.056 | Human | |
ADAMDEC1 | ADAM-like, decysin 1 | 0.056 | ||
FAF1 | Fas (TNFRSF6) associated factor 1 | 0.055 | ||
F3 | coagulation factor III (thromboplastin, tissue factor) | 0.055 | ||
NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 | 0.055 | Human | |
PAX8 | paired box 8 | 0.055 | ||
SIT1 | signaling threshold regulating transmembrane adaptor 1 | 0.055 | ||
TRAF3 | TNF receptor-associated factor 3 | 0.055 | ||
CXCR1 | chemokine (C-X-C motif) receptor 1 | 0.055 | Human | |
CD22 | CD22 molecule | 0.055 | ||
TFPI2 | tissue factor pathway inhibitor 2 | 0.055 | ||
IL13 | interleukin 13 | 0.055 | ||
PRPF38A | PRP38 pre-mRNA processing factor 38 (yeast) domain containing A | 0.055 | ||
NCK1 | NCK adaptor protein 1 | 0.055 | ||
WNT1 | wingless-type MMTV integration site family, member 1 | 0.055 | ||
CH25H | cholesterol 25-hydroxylase | 0.055 | ||
EMP1 | epithelial membrane protein 1 | 0.055 | ||
C1orf93 | chromosome 1 open reading frame 93 | 0.055 | ||
ADORA3 | adenosine A3 receptor | 0.054 | ||
HSPB1 | heat shock 27kDa protein 1 | 0.054 | ||
SH2D2A | SH2 domain containing 2A | 0.054 | ||
IL2RA | interleukin 2 receptor, alpha | 0.054 | ||
CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.053 | ||
ERBB2IP | erbb2 interacting protein | 0.053 | ||
VCAN | versican | 0.053 | ||
GREM1 | gremlin 1 | 0.053 | ||
IDE | insulin-degrading enzyme | 0.053 | ||
PILRA | paired immunoglobin-like type 2 receptor alpha | 0.053 | ||
PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) | 0.053 | ||
GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | 0.053 | ||
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.052 | ||
THRA | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 0.052 | ||
DNASE1L3 | deoxyribonuclease I-like 3 | 0.052 | ||
NRIP1 | nuclear receptor interacting protein 1 | 0.052 | ||
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.052 | ||
VRK2 | vaccinia related kinase 2 | 0.052 | Fly | |
ARRDC3 | arrestin domain containing 3 | 0.052 | ||
ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.052 | ||
MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.052 | ||
NLRC4 | NLR family, CARD domain containing 4 | 0.052 | ||
CD86 | CD86 molecule | 0.052 | ||
MATK | megakaryocyte-associated tyrosine kinase | 0.052 | ||
SOD2 | superoxide dismutase 2, mitochondrial | 0.052 | ||
MYLK2 | myosin light chain kinase 2 | 0.052 | ||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.052 | ||
BCL10 | B-cell CLL/lymphoma 10 | 0.052 | ||
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.051 | ||
EREG | epiregulin | 0.051 | ||
TSC2 | tuberous sclerosis 2 | 0.051 | ||
CCR9 | chemokine (C-C motif) receptor 9 | 0.051 | Human | |
MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.050 | ||
IL6R | interleukin 6 receptor | 0.050 | ||
MCL1 | myeloid cell leukemia sequence 1 (BCL2-related) | 0.050 | ||
CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.050 | ||
COL1A1 | collagen, type I, alpha 1 | 0.050 | ||
CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.050 | ||
DST | dystonin | 0.050 | ||
BMP2 | bone morphogenetic protein 2 | 0.050 | ||
FES | feline sarcoma oncogene | 0.050 | ||
TBC1D10A | TBC1 domain family, member 10A | 0.050 | ||
PIM1 | pim-1 oncogene | 0.050 | ||
PGF | placental growth factor | 0.050 | Human | |
GPR109B | G protein-coupled receptor 109B | 0.050 | ||
RHEB | Ras homolog enriched in brain | 0.049 | ||
FLT4 | fms-related tyrosine kinase 4 | 0.049 | ||
SLC26A3 | solute carrier family 26, member 3 | 0.049 | ||
ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) | 0.049 | ||
CXCR5 | chemokine (C-X-C motif) receptor 5 | 0.049 | Human | |
MAPK11 | mitogen-activated protein kinase 11 | 0.049 | ||
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.049 | ||
PTPRD | protein tyrosine phosphatase, receptor type, D | 0.048 | ||
ROD1 | ROD1 regulator of differentiation 1 (S. pombe) | 0.048 | ||
EPHA1 | EPH receptor A1 | 0.048 | Human | |
LRRK2 | leucine-rich repeat kinase 2 | 0.048 | ||
CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 | 0.048 | ||
CCR6 | chemokine (C-C motif) receptor 6 | 0.048 | Human | |
FGF4 | fibroblast growth factor 4 | 0.048 | ||
FCGR2C | Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene) | 0.048 | ||
SOS2 | son of sevenless homolog 2 (Drosophila) | 0.047 | ||
SMG1 | SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) | 0.047 | ||
TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.047 | ||
PDCD1 | programmed cell death 1 | 0.047 | ||
TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | 0.047 | ||
CCL1 | chemokine (C-C motif) ligand 1 | 0.047 | Human | |
THBS2 | thrombospondin 2 | 0.047 | ||
PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.047 | ||
APP | amyloid beta (A4) precursor protein | 0.047 | ||
RND1 | Rho family GTPase 1 | 0.047 | ||
SNRNP70 | small nuclear ribonucleoprotein 70kDa (U1) | 0.046 | ||
TRAF3IP3 | TRAF3 interacting protein 3 | 0.046 | ||
RIN2 | Ras and Rab interactor 2 | 0.046 | ||
BLK | B lymphoid tyrosine kinase | 0.046 | ||
PKN2 | protein kinase N2 | 0.046 | ||
MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 | 0.046 | ||
KITLG | KIT ligand | 0.046 | ||
CR1 | complement component (3b/4b) receptor 1 (Knops blood group) | 0.046 | ||
NCF1 | neutrophil cytosolic factor 1 | 0.046 | ||
CRYBB1 | crystallin, beta B1 | 0.046 | ||
SLIT2 | slit homolog 2 (Drosophila) | 0.046 | ||
IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.046 | ||
MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.046 | ||
TLR4 | toll-like receptor 4 | 0.046 | Mouse | |
DR1 | down-regulator of transcription 1, TBP-binding (negative cofactor 2) | 0.045 | ||
CCL17 | chemokine (C-C motif) ligand 17 | 0.045 | Human | |
CLEC3B | C-type lectin domain family 3, member B | 0.045 | ||
HIPK1 | homeodomain interacting protein kinase 1 | 0.045 | ||
COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.045 | ||
IGF1 | insulin-like growth factor 1 (somatomedin C) | 0.045 | Mouse | |
SH2B2 | SH2B adaptor protein 2 | 0.045 | ||
STAB1 | stabilin 1 | 0.044 | ||
MAP2 | microtubule-associated protein 2 | 0.044 | ||
NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.044 | ||
BTK | Bruton agammaglobulinemia tyrosine kinase | 0.044 | ||
FHOD3 | formin homology 2 domain containing 3 | 0.044 | ||
SRRM1 | serine/arginine repetitive matrix 1 | 0.044 | ||
CAPRIN2 | caprin family member 2 | 0.044 | ||
IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.044 | ||
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.044 | ||
NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.044 | ||
MED28 | mediator complex subunit 28 | 0.044 | ||
CALCR | calcitonin receptor | 0.044 | ||
PLXDC1 | plexin domain containing 1 | 0.044 | ||
AKAP12 | A kinase (PRKA) anchor protein 12 | 0.044 | ||
IL1F5 | interleukin 1 family, member 5 (delta) | 0.044 | ||
NOTCH3 | notch 3 | 0.044 | ||
EFNA2 | ephrin-A2 | 0.044 | ||
IL21R | interleukin 21 receptor | 0.043 | ||
PTH1R | parathyroid hormone 1 receptor | 0.043 | ||
PRKCD | protein kinase C, delta | 0.043 | Human | |
DCN | decorin | 0.043 | ||
CALCRL | calcitonin receptor-like | 0.043 | ||
SYK | spleen tyrosine kinase | 0.042 | Mouse | |
CSDA | cold shock domain protein A | 0.042 | ||
BTLA | B and T lymphocyte associated | 0.042 | ||
BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.042 | ||
AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.042 | ||
GJA4 | gap junction protein, alpha 4, 37kDa | 0.042 | ||
AGTR1 | angiotensin II receptor, type 1 | 0.042 | ||
CSF1R | colony stimulating factor 1 receptor | 0.042 | Human Mouse | |
IL12B | interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) | 0.042 | ||
PKM2 | pyruvate kinase, muscle | 0.042 | ||
COMP | cartilage oligomeric matrix protein | 0.042 | ||
LMO4 | LIM domain only 4 | 0.042 | Human | |
C19orf46 | chromosome 19 open reading frame 46 | 0.042 | ||
IL3RA | interleukin 3 receptor, alpha (low affinity) | 0.042 | ||
RELN | reelin | 0.041 | ||
HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E | 0.041 | Human | |
SIRPA | signal-regulatory protein alpha | 0.041 | ||
JAK1 | Janus kinase 1 | 0.041 | ||
SLC16A8 | solute carrier family 16, member 8 (monocarboxylic acid transporter 3) | 0.041 | ||
SPHK1 | sphingosine kinase 1 | 0.041 | ||
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.041 | ||
NKAP | NFKB activating protein | 0.041 | ||
EFNB3 | ephrin-B3 | 0.041 | ||
CLEC4E | C-type lectin domain family 4, member E | 0.041 | ||
KCNJ15 | potassium inwardly-rectifying channel, subfamily J, member 15 | 0.041 | ||
UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.041 | ||
HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B | 0.041 | Human | |
JUN | jun proto-oncogene | 0.041 | ||
MMP7 | matrix metallopeptidase 7 (matrilysin, uterine) | 0.041 | ||
IDO1 | indoleamine 2,3-dioxygenase 1 | 0.041 | ||
KCNJ5 | potassium inwardly-rectifying channel, subfamily J, member 5 | 0.041 | ||
IL4 | interleukin 4 | 0.040 | ||
NOTCH4 | notch 4 | 0.040 | ||
JAK3 | Janus kinase 3 | 0.040 | ||
CLEC5A | C-type lectin domain family 5, member A | 0.040 | ||
ANXA1 | annexin A1 | 0.040 | ||
MMP1 | matrix metallopeptidase 1 (interstitial collagenase) | 0.040 | ||
C3AR1 | complement component 3a receptor 1 | 0.040 | Human | |
CHI3L2 | chitinase 3-like 2 | 0.040 | Human | |
EPOR | erythropoietin receptor | 0.040 | ||
NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.040 | Mouse | |
P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 | 0.040 | Human | |
CDK13 | cyclin-dependent kinase 13 | 0.040 | Fly | |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.040 | ||
GDNF | glial cell derived neurotrophic factor | 0.040 | ||
LOXL2 | lysyl oxidase-like 2 | 0.040 | ||
TP73 | tumor protein p73 | 0.040 | ||
CSNK2A1 | casein kinase 2, alpha 1 polypeptide | 0.039 | ||
CAMP | cathelicidin antimicrobial peptide | 0.039 | ||
CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.039 | ||
GNMT | glycine N-methyltransferase | 0.039 | ||
DLG2 | discs, large homolog 2 (Drosophila) | 0.039 | ||
CD93 | CD93 molecule | 0.039 | ||
RNF11 | ring finger protein 11 | 0.039 | ||
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.039 | ||
RBP4 | retinol binding protein 4, plasma | 0.039 | ||
EVI2A | ecotropic viral integration site 2A | 0.039 | ||
TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.039 | ||
DPP6 | dipeptidyl-peptidase 6 | 0.039 | ||
ITGAL | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 0.039 | ||
MMP11 | matrix metallopeptidase 11 (stromelysin 3) | 0.038 | ||
GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.038 | ||
GJA5 | gap junction protein, alpha 5, 40kDa | 0.038 | ||
DHX8 | DEAH (Asp-Glu-Ala-His) box polypeptide 8 | 0.038 | ||
RPS6KA1 | ribosomal protein S6 kinase, 90kDa, polypeptide 1 | 0.038 | ||
SEC24D | SEC24 family, member D (S. cerevisiae) | 0.038 | ||
RND3 | Rho family GTPase 3 | 0.038 | ||
HGF | hepatocyte growth factor (hepapoietin A; scatter factor) | 0.038 | ||
CYTIP | cytohesin 1 interacting protein | 0.038 | ||
F2 | coagulation factor II (thrombin) | 0.038 | ||
CD72 | CD72 molecule | 0.038 | ||
TRIB1 | tribbles homolog 1 (Drosophila) | 0.038 | ||
TLR7 | toll-like receptor 7 | 0.038 | ||
RAP1GAP | RAP1 GTPase activating protein | 0.038 | ||
ALOX5 | arachidonate 5-lipoxygenase | 0.038 | Human | |
DLG4 | discs, large homolog 4 (Drosophila) | 0.038 | ||
MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.038 | ||
SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.037 | ||
CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.037 | ||
FRA10AC1 | fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1 | 0.037 | ||
SIKE1 | suppressor of IKBKE 1 | 0.037 | ||
HAS2 | hyaluronan synthase 2 | 0.037 | ||
PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.037 | ||
HSPA1L | heat shock 70kDa protein 1-like | 0.037 | ||
AMOT | angiomotin | 0.037 | ||
SLC15A3 | solute carrier family 15, member 3 | 0.037 | ||
SFRP4 | secreted frizzled-related protein 4 | 0.037 | ||
TIFA | TRAF-interacting protein with forkhead-associated domain | 0.037 | ||
F2RL3 | coagulation factor II (thrombin) receptor-like 3 | 0.037 | ||
AVPR2 | arginine vasopressin receptor 2 | 0.037 | ||
GPSM3 | G-protein signaling modulator 3 | 0.037 | ||
CCL23 | chemokine (C-C motif) ligand 23 | 0.037 | Human | |
MUSK | muscle, skeletal, receptor tyrosine kinase | 0.036 | Human | |
RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 | 0.036 | ||
CD226 | CD226 molecule | 0.036 | ||
LHX5 | LIM homeobox 5 | 0.036 | ||
S100A9 | S100 calcium binding protein A9 | 0.036 | ||
ADRB2 | adrenergic, beta-2-, receptor, surface | 0.036 | Human | |
CCL21 | chemokine (C-C motif) ligand 21 | 0.036 | ||
HTR2C | 5-hydroxytryptamine (serotonin) receptor 2C | 0.036 | ||
SFRP1 | secreted frizzled-related protein 1 | 0.036 | ||
PLAU | plasminogen activator, urokinase | 0.036 | ||
CCR8 | chemokine (C-C motif) receptor 8 | 0.036 | Human | |
CSF3 | colony stimulating factor 3 (granulocyte) | 0.036 | ||
HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.036 | ||
PLEK | pleckstrin | 0.036 | ||
THBD | thrombomodulin | 0.036 | ||
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.035 | ||
APOD | apolipoprotein D | 0.035 | ||
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.035 | ||
LAG3 | lymphocyte-activation gene 3 | 0.035 | ||
IL18BP | interleukin 18 binding protein | 0.035 | ||
GLIS2 | GLIS family zinc finger 2 | 0.035 | ||
MSC | musculin | 0.035 | ||
LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.035 | ||
ACE | angiotensin I converting enzyme (peptidyl-dipeptidase A) 1 | 0.035 | ||
MYBPC3 | myosin binding protein C, cardiac | 0.035 | ||
RNASE3 | ribonuclease, RNase A family, 3 | 0.034 | ||
ITGA1 | integrin, alpha 1 | 0.034 | ||
GPR171 | G protein-coupled receptor 171 | 0.034 | ||
STK3 | serine/threonine kinase 3 | 0.034 | ||
FHL2 | four and a half LIM domains 2 | 0.034 | ||
OR2AG1 | olfactory receptor, family 2, subfamily AG, member 1 | 0.034 | ||
TESK1 | testis-specific kinase 1 | 0.034 | ||
FFAR2 | free fatty acid receptor 2 | 0.034 |