IMP
Process View
amyloid precursor protein metabolic process
The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "amyloid precursor protein metabolic process"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| NCSTN | nicastrin | 0.786 | ||
| FLOT2 | flotillin 2 | 0.669 | ||
| SYNRG | synergin, gamma | 0.651 | ||
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 | 0.635 | ||
| FLOT1 | flotillin 1 | 0.595 | Human | |
| APP | amyloid beta (A4) precursor protein | 0.536 | ||
| EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.369 | ||
| RNF11 | ring finger protein 11 | 0.340 | ||
| PSEN1 | presenilin 1 | 0.288 | Zebrafish Mouse | |
| PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.261 | ||
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 | 0.235 | ||
| LAMP2 | lysosomal-associated membrane protein 2 | 0.229 | ||
| HP | haptoglobin | 0.127 | ||
| PKP4 | plakophilin 4 | 0.116 | ||
| APH1A | anterior pharynx defective 1 homolog A (C. elegans) | 0.102 | ||
| IGF2R | insulin-like growth factor 2 receptor | 0.094 | ||
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.079 | ||
| SORT1 | sortilin 1 | 0.072 | Human | |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.070 | ||
| ACVR1B | activin A receptor, type IB | 0.064 | ||
| AGFG1 | ArfGAP with FG repeats 1 | 0.052 | ||
| A2M | alpha-2-macroglobulin | 0.047 | ||
| STON2 | stonin 2 | 0.045 | ||
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.044 | ||
| FLNB | filamin B, beta | 0.043 | ||
| CANX | calnexin | 0.035 | ||
| LCAT | lecithin-cholesterol acyltransferase | 0.033 | ||
| DHCR7 | 7-dehydrocholesterol reductase | 0.033 | ||
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.033 | ||
| APOC1 | apolipoprotein C-I | 0.028 | ||
| PSENEN | presenilin enhancer 2 homolog (C. elegans) | 0.027 | ||
| ARCN1 | archain 1 | 0.026 | ||
| PRKCZ | protein kinase C, zeta | 0.026 | ||
| AP2A1 | adaptor-related protein complex 2, alpha 1 subunit | 0.025 | ||
| VAMP3 | vesicle-associated membrane protein 3 (cellubrevin) | 0.022 | ||
| SPG21 | spastic paraplegia 21 (autosomal recessive, Mast syndrome) | 0.021 | ||
| LNX1 | ligand of numb-protein X 1 | 0.020 | ||
| BCL2L1 | BCL2-like 1 | 0.019 | ||
| FCHO2 | FCH domain only 2 | 0.019 | ||
| MAPT | microtubule-associated protein tau | 0.019 | ||
| ARF3 | ADP-ribosylation factor 3 | 0.019 | ||
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 | 0.019 | ||
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.019 | ||
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.018 | ||
| TRAF5 | TNF receptor-associated factor 5 | 0.018 | ||
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.016 | ||
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.015 | ||
| TTR | transthyretin | 0.015 | ||
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.015 | ||
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.015 | ||
| APBA1 | amyloid beta (A4) precursor protein-binding, family A, member 1 | 0.014 | ||
| APOC3 | apolipoprotein C-III | 0.014 | ||
| SNAP23 | synaptosomal-associated protein, 23kDa | 0.014 | ||
| TRIM32 | tripartite motif containing 32 | 0.013 | ||
| COPA | coatomer protein complex, subunit alpha | 0.013 | ||
| MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.013 | ||
| PRNP | prion protein | 0.013 | ||
| GNS | glucosamine (N-acetyl)-6-sulfatase | 0.012 | ||
| UNC45A | unc-45 homolog A (C. elegans) | 0.012 | ||
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.012 | ||
| POLR2J | polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa | 0.012 | ||
| ABI1 | abl-interactor 1 | 0.012 | ||
| NUMB | numb homolog (Drosophila) | 0.012 | Human | |
| B2M | beta-2-microglobulin | 0.012 | ||
| MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.011 | ||
| LAMP1 | lysosomal-associated membrane protein 1 | 0.011 | ||
| RPN2 | ribophorin II | 0.011 | ||
| ATP6AP2 | ATPase, H+ transporting, lysosomal accessory protein 2 | 0.011 | ||
| TGOLN2 | trans-golgi network protein 2 | 0.011 | ||
| ADORA2A | adenosine A2a receptor | 0.011 | ||
| STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.011 | ||
| NPTN | neuroplastin | 0.011 | ||
| RNF13 | ring finger protein 13 | 0.010 | ||
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 0.010 | ||
| UBQLN4 | ubiquilin 4 | 0.010 | ||
| SERINC1 | serine incorporator 1 | 0.010 |