2 genes annotated in humanMulti-species View
The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.
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Click on a gene's description to view its network relationships with genes known to be involved in "protein retention in golgi apparatus"
|Name||Description||Probability||Func Analog Organism|
|GGA1||golgi-associated, gamma adaptin ear containing, ARF binding protein 1||0.170|
|GGA2||golgi-associated, gamma adaptin ear containing, ARF binding protein 2||0.079|
|IGF2R||insulin-like growth factor 2 receptor||0.014|