IMP
Process View
microtubule nucleation
The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "microtubule nucleation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| TUBGCP3 | tubulin, gamma complex associated protein 3 | 0.991 | Fly | |
| MZT1 | mitotic spindle organizing protein 1 | 0.818 | ||
| TACC3 | transforming, acidic coiled-coil containing protein 3 | 0.770 | ||
| CKAP5 | cytoskeleton associated protein 5 | 0.702 | Fly | |
| AURKA | aurora kinase A | 0.694 | ||
| KIF1B | kinesin family member 1B | 0.538 | ||
| TUBB2C | tubulin, beta 2C | 0.501 | ||
| MZT2B | mitotic spindle organizing protein 2B | 0.457 | ||
| TUBB | tubulin, beta | 0.405 | ||
| NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.386 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.374 | ||
| TUBA1C | tubulin, alpha 1c | 0.191 | ||
| GTSE1 | G-2 and S-phase expressed 1 | 0.179 | ||
| TUBA1B | tubulin, alpha 1b | 0.171 | ||
| TUBG1 | tubulin, gamma 1 | 0.134 | Worm | |
| TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 0.129 | ||
| CEP55 | centrosomal protein 55kDa | 0.126 | ||
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.104 | ||
| TUBGCP5 | tubulin, gamma complex associated protein 5 | 0.091 | ||
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.076 | ||
| BICD1 | bicaudal D homolog 1 (Drosophila) | 0.073 | ||
| UBE2S | ubiquitin-conjugating enzyme E2S | 0.063 | ||
| C13orf34 | chromosome 13 open reading frame 34 | 0.063 | ||
| PLK1 | polo-like kinase 1 | 0.060 | Fly | |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 | 0.046 | ||
| GSK3B | glycogen synthase kinase 3 beta | 0.042 | ||
| IMMT | inner membrane protein, mitochondrial | 0.039 | ||
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.039 | ||
| CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.036 | ||
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.035 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.033 | ||
| TUBB3 | tubulin, beta 3 | 0.027 | ||
| SRPK1 | SRSF protein kinase 1 | 0.023 | ||
| API5 | apoptosis inhibitor 5 | 0.021 | ||
| FBXW11 | F-box and WD repeat domain containing 11 | 0.021 | ||
| TACC1 | transforming, acidic coiled-coil containing protein 1 | 0.020 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.020 | ||
| TUBGCP2 | tubulin, gamma complex associated protein 2 | 0.020 | Fly | |
| AKAP9 | A kinase (PRKA) anchor protein (yotiao) 9 | 0.019 | ||
| KIF4A | kinesin family member 4A | 0.019 | ||
| CENPF | centromere protein F, 350/400kDa (mitosin) | 0.018 | ||
| MUS81 | MUS81 endonuclease homolog (S. cerevisiae) | 0.016 | ||
| TUBA4A | tubulin, alpha 4a | 0.016 | ||
| ARIH2 | ariadne homolog 2 (Drosophila) | 0.016 | ||
| CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.015 | ||
| CDC25B | cell division cycle 25 homolog B (S. pombe) | 0.015 | ||
| NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.014 | ||
| RAD21 | RAD21 homolog (S. pombe) | 0.013 | ||
| GPSM2 | G-protein signaling modulator 2 | 0.013 | ||
| FOXM1 | forkhead box M1 | 0.013 | ||
| ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.012 | ||
| APC | adenomatous polyposis coli | 0.012 | ||
| PTTG1 | pituitary tumor-transforming 1 | 0.012 | ||
| KIF22 | kinesin family member 22 | 0.011 | ||
| LMO4 | LIM domain only 4 | 0.011 | ||
| NUP50 | nucleoporin 50kDa | 0.011 | ||
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.011 | ||
| CIT | citron (rho-interacting, serine/threonine kinase 21) | 0.011 | ||
| MKI67 | antigen identified by monoclonal antibody Ki-67 | 0.011 | ||
| PUM2 | pumilio homolog 2 (Drosophila) | 0.011 | ||
| ERCC6L | excision repair cross-complementing rodent repair deficiency, complementation group 6-like | 0.011 | ||
| ZNF71 | zinc finger protein 71 | 0.010 |