IMP: Integrative Multi-species Prediction

Homo sapiens

19 genes annotated in human

Multi-species View

regulation of histone acetylation

GO:0035065

Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of histone acetylation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of histone acetylation" (in gray)

Name	Description	Probability	Func Analog Organism
WDR5	WD repeat domain 5	0.941
MAPK14	mitogen-activated protein kinase 14	0.511
MAPK3	mitogen-activated protein kinase 3	0.446
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.267
ZNF496	zinc finger protein 496	0.255
HCFC1	host cell factor C1 (VP16-accessory protein)	0.243
MAPK1	mitogen-activated protein kinase 1	0.224	Human
CHD8	chromodomain helicase DNA binding protein 8	0.204
ARRB2	arrestin, beta 2	0.203	Human
MBIP	MAP3K12 binding inhibitory protein 1	0.200
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.173
BCL9	B-cell CLL/lymphoma 9	0.163
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.157
SETD8	SET domain containing (lysine methyltransferase) 8	0.155
TGIF1	TGFB-induced factor homeobox 1	0.150
COASY	CoA synthase	0.144
ARRB1	arrestin, beta 1	0.140
HIPK2	homeodomain interacting protein kinase 2	0.137
ENG	endoglin	0.136
TAL1	T-cell acute lymphocytic leukemia 1	0.131
VAC14	Vac14 homolog (S. cerevisiae)	0.129
RBBP5	retinoblastoma binding protein 5	0.122
NRIP1	nuclear receptor interacting protein 1	0.106
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.090
EP300	E1A binding protein p300	0.086
CDAN1	congenital dyserythropoietic anemia, type I	0.081
RUNX1	runt-related transcription factor 1	0.080
RUVBL1	RuvB-like 1 (E. coli)	0.080
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.077	Yeast
PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	0.076
MAP2K4	mitogen-activated protein kinase kinase 4	0.076
DUSP1	dual specificity phosphatase 1	0.076
ASH2L	ash2 (absent, small, or homeotic)-like (Drosophila)	0.075
CFL1	cofilin 1 (non-muscle)	0.072
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.072
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.072
MASP1	mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)	0.071
RB1	retinoblastoma 1	0.068
YY1	YY1 transcription factor	0.065
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.059
SMC1A	structural maintenance of chromosomes 1A	0.059
DUSP3	dual specificity phosphatase 3	0.058
NCOA6	nuclear receptor coactivator 6	0.055
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.052
WWOX	WW domain containing oxidoreductase	0.051
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.051
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.050
EED	embryonic ectoderm development	0.048
CTBP1	C-terminal binding protein 1	0.047
BRCA1	breast cancer 1, early onset	0.047
EEF2K	eukaryotic elongation factor-2 kinase	0.046
GSK3B	glycogen synthase kinase 3 beta	0.045
INO80	INO80 homolog (S. cerevisiae)	0.044
PML	promyelocytic leukemia	0.042
SRF	serum response factor (c-fos serum response element-binding transcription factor)	0.037
MRFAP1L1	Morf4 family associated protein 1-like 1	0.037
CCDC101	coiled-coil domain containing 101	0.036
ATM	ataxia telangiectasia mutated	0.035
BARD1	BRCA1 associated RING domain 1	0.035
USP22	ubiquitin specific peptidase 22	0.032
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.031
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	0.030
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.030
MATR3	matrin 3	0.030
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.029
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.029
MEN1	multiple endocrine neoplasia I	0.029
MAP2K1	mitogen-activated protein kinase kinase 1	0.029
TLK1	tousled-like kinase 1	0.028
HDAC1	histone deacetylase 1	0.027
STAG1	stromal antigen 1	0.027
SETD7	SET domain containing (lysine methyltransferase) 7	0.026
KAT5	K(lysine) acetyltransferase 5	0.026
USP5	ubiquitin specific peptidase 5 (isopeptidase T)	0.026
PEA15	phosphoprotein enriched in astrocytes 15	0.025
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.025
TRRAP	transformation/transcription domain-associated protein	0.024
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.024
ESR1	estrogen receptor 1	0.024
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.024
TBP	TATA box binding protein	0.023
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.023
PRKCA	protein kinase C, alpha	0.023
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.023
MBP	myelin basic protein	0.022
CREB1	cAMP responsive element binding protein 1	0.022
SOX13	SRY (sex determining region Y)-box 13	0.022
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.022
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.022
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.022
TP53BP1	tumor protein p53 binding protein 1	0.022
MYST1	MYST histone acetyltransferase 1	0.021	Fly
ATXN7	ataxin 7	0.021
PARP1	poly (ADP-ribose) polymerase 1	0.021
FZD5	frizzled homolog 5 (Drosophila)	0.020
EIF3C	eukaryotic translation initiation factor 3, subunit C	0.020
GDI1	GDP dissociation inhibitor 1	0.020
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.020
GPBP1	GC-rich promoter binding protein 1	0.020
C19orf46	chromosome 19 open reading frame 46	0.020
ZBTB4	zinc finger and BTB domain containing 4	0.020
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.020
ATG12	ATG12 autophagy related 12 homolog (S. cerevisiae)	0.019
DUSP7	dual specificity phosphatase 7	0.019
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.019
USP16	ubiquitin specific peptidase 16	0.019
PTPRR	protein tyrosine phosphatase, receptor type, R	0.018
MAPK8	mitogen-activated protein kinase 8	0.018
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.018
KAT2A	K(lysine) acetyltransferase 2A	0.018
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.018
C10orf116	chromosome 10 open reading frame 116	0.018
YAF2	YY1 associated factor 2	0.018
CREBBP	CREB binding protein	0.018
AFF1	AF4/FMR2 family, member 1	0.018
RPA1	replication protein A1, 70kDa	0.017
GNMT	glycine N-methyltransferase	0.017
RNF19A	ring finger protein 19A	0.017
CTBP2	C-terminal binding protein 2	0.017	Human
BCLAF1	BCL2-associated transcription factor 1	0.017
SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	0.016
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.016
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.016
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.016
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.016
ELK1	ELK1, member of ETS oncogene family	0.016
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.015
CCNH	cyclin H	0.015
IK	IK cytokine, down-regulator of HLA II	0.015
H2AFX	H2A histone family, member X	0.015
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.015
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.015
MDC1	mediator of DNA-damage checkpoint 1	0.015
EAPP	E2F-associated phosphoprotein	0.015
MSH6	mutS homolog 6 (E. coli)	0.014
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.014
MAGEF1	melanoma antigen family F, 1	0.014
VEZF1	vascular endothelial zinc finger 1	0.013
THAP11	THAP domain containing 11	0.013
HIC1	hypermethylated in cancer 1	0.013
ATF1	activating transcription factor 1	0.013
CLSPN	claspin	0.013
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.013
PIAS4	protein inhibitor of activated STAT, 4	0.013
FSTL1	follistatin-like 1	0.013
FES	feline sarcoma oncogene	0.013
RICTOR	RPTOR independent companion of MTOR, complex 2	0.013
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.013
MAPK10	mitogen-activated protein kinase 10	0.013
MAGEH1	melanoma antigen family H, 1	0.012
CXXC1	CXXC finger protein 1	0.012
MORF4L1	mortality factor 4 like 1	0.012
SMAD6	SMAD family member 6	0.012
ZNF219	zinc finger protein 219	0.012
ACTR5	ARP5 actin-related protein 5 homolog (yeast)	0.012
C20orf20	chromosome 20 open reading frame 20	0.012
WAPAL	wings apart-like homolog (Drosophila)	0.012
PCID2	PCI domain containing 2	0.012
MPP1	membrane protein, palmitoylated 1, 55kDa	0.012
MAP2K7	mitogen-activated protein kinase kinase 7	0.012
MCM7	minichromosome maintenance complex component 7	0.012
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	0.011
FBXW7	F-box and WD repeat domain containing 7	0.011
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.011
AKT1S1	AKT1 substrate 1 (proline-rich)	0.011
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.011
VTA1	Vps20-associated 1 homolog (S. cerevisiae)	0.011
DHX34	DEAH (Asp-Glu-Ala-His) box polypeptide 34	0.011
SPRR2A	small proline-rich protein 2A	0.011
KAT2B	K(lysine) acetyltransferase 2B	0.011
TPPP	tubulin polymerization promoting protein	0.011
LIMK1	LIM domain kinase 1	0.011
TP53	tumor protein p53	0.011
CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	0.011
C16orf53	chromosome 16 open reading frame 53	0.010
UBE3A	ubiquitin protein ligase E3A	0.010
LIFR	leukemia inhibitory factor receptor alpha	0.010
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	0.010
ING3	inhibitor of growth family, member 3	0.010
ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	0.010
ING5	inhibitor of growth family, member 5	0.010
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.010
USP42	ubiquitin specific peptidase 42	0.010