IMP: Integrative Multi-species Prediction

Homo sapiens

60 genes annotated in human

Multi-species View

positive regulation of mitotic cell cycle

GO:0045931

Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mitotic cell cycle"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of mitotic cell cycle" (in gray)

Name	Description	Probability	Func Analog Organism
CDK2	cyclin-dependent kinase 2	1.000	Yeast
RB1	retinoblastoma 1	0.998
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.988
CCNA2	cyclin A2	0.978
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.971
EGFR	epidermal growth factor receptor	0.962
NOTCH1	notch 1	0.961	Fly
INSR	insulin receptor	0.954
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.921
JAK2	Janus kinase 2	0.910
PLK1	polo-like kinase 1	0.844
JAG1	jagged 1	0.821
CCNE1	cyclin E1	0.819	Fly
E2F1	E2F transcription factor 1	0.814
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.791
SKP2	S-phase kinase-associated protein 2 (p45)	0.766
RBL1	retinoblastoma-like 1 (p107)	0.759	Human
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.736	Yeast Fly
CCND1	cyclin D1	0.709
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.701	Human Fly
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.700
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.672
PRKCA	protein kinase C, alpha	0.642
ORC1	origin recognition complex, subunit 1	0.626
BRCA1	breast cancer 1, early onset	0.609
CDK6	cyclin-dependent kinase 6	0.585	Human Worm
C19orf39	chromosome 19 open reading frame 39	0.571
WAPAL	wings apart-like homolog (Drosophila)	0.571
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.564
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.531	Mouse
IGF1R	insulin-like growth factor 1 receptor	0.529	Human Mouse
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.528
CDK1	cyclin-dependent kinase 1	0.521	Yeast Rat
HDAC1	histone deacetylase 1	0.510
ACTN2	actinin, alpha 2	0.492
GRB10	growth factor receptor-bound protein 10	0.474
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.470
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.466
ARHGAP10	Rho GTPase activating protein 10	0.456
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.453
IRS1	insulin receptor substrate 1	0.399
BRCA2	breast cancer 2, early onset	0.398	Mouse
EP300	E1A binding protein p300	0.394
CDT1	chromatin licensing and DNA replication factor 1	0.386
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.376
CAV1	caveolin 1, caveolae protein, 22kDa	0.374
CDKN3	cyclin-dependent kinase inhibitor 3	0.363
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.362
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.359
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.352
RAD51L3	RAD51-like 3 (S. cerevisiae)	0.347
MYBL2	v-myb myeloblastosis viral oncogene homolog (avian)-like 2	0.343	Fly
CCND3	cyclin D3	0.329	Human
CLSPN	claspin	0.323
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.282	Mouse
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.280
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.279
H2AFX	H2A histone family, member X	0.279
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.277
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.265
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.248
VHL	von Hippel-Lindau tumor suppressor	0.241
RAD51L1	RAD51-like 1 (S. cerevisiae)	0.237
CCNB2	cyclin B2	0.231	Human
IL1R1	interleukin 1 receptor, type I	0.230
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.227
CD80	CD80 molecule	0.226
EIF4EBP1	eukaryotic translation initiation factor 4E binding protein 1	0.222
CNOT2	CCR4-NOT transcription complex, subunit 2	0.219
ORC2	origin recognition complex, subunit 2	0.205
FUBP1	far upstream element (FUSE) binding protein 1	0.199
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.191
FOXM1	forkhead box M1	0.190
SMC3	structural maintenance of chromosomes 3	0.189
EIF4EBP3	eukaryotic translation initiation factor 4E binding protein 3	0.188
POU5F1	POU class 5 homeobox 1	0.188
CCNF	cyclin F	0.181
CCNB1	cyclin B1	0.172
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.172
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.170
NCOR2	nuclear receptor corepressor 2	0.163
PCGF2	polycomb group ring finger 2	0.162
GRAP2	GRB2-related adaptor protein 2	0.158
CCNE2	cyclin E2	0.155	Fly
E2F4	E2F transcription factor 4, p107/p130-binding	0.152
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.150
CDC7	cell division cycle 7 homolog (S. cerevisiae)	0.146
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.140
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.139
HIPK2	homeodomain interacting protein kinase 2	0.139
BLM	Bloom syndrome, RecQ helicase-like	0.135
IL1RAP	interleukin 1 receptor accessory protein	0.135
IARS	isoleucyl-tRNA synthetase	0.133
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.125
LIN9	lin-9 homolog (C. elegans)	0.124
ORC3	origin recognition complex, subunit 3	0.124
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.123
MBNL1	muscleblind-like (Drosophila)	0.122
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.117
ANAPC4	anaphase promoting complex subunit 4	0.116
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.111
RBBP4	retinoblastoma binding protein 4	0.111
STAG2	stromal antigen 2	0.110
STK36	serine/threonine kinase 36	0.107
MEIS1	Meis homeobox 1	0.107
MAPK1	mitogen-activated protein kinase 1	0.107
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.104
MAPK14	mitogen-activated protein kinase 14	0.100
RAD51C	RAD51 homolog C (S. cerevisiae)	0.099
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.098
MEIS2	Meis homeobox 2	0.098
SHMT2	serine hydroxymethyltransferase 2 (mitochondrial)	0.095
RAD21	RAD21 homolog (S. pombe)	0.094
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.093
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.093
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.092
NCF1	neutrophil cytosolic factor 1	0.090
DDB1	damage-specific DNA binding protein 1, 127kDa	0.089
GAB1	GRB2-associated binding protein 1	0.089
SMC6	structural maintenance of chromosomes 6	0.088
SETD8	SET domain containing (lysine methyltransferase) 8	0.085
GARS	glycyl-tRNA synthetase	0.081
RBL2	retinoblastoma-like 2 (p130)	0.078	Human
MCM10	minichromosome maintenance complex component 10	0.078	Fly
CKS2	CDC28 protein kinase regulatory subunit 2	0.077
ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.074
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.073
MAML1	mastermind-like 1 (Drosophila)	0.073
CCND2	cyclin D2	0.073	Human
PEA15	phosphoprotein enriched in astrocytes 15	0.072
TFDP1	transcription factor Dp-1	0.072
KAT2B	K(lysine) acetyltransferase 2B	0.071
MKI67	antigen identified by monoclonal antibody Ki-67	0.071
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.071
CDCA8	cell division cycle associated 8	0.069
ZNF282	zinc finger protein 282	0.069
GTSE1	G-2 and S-phase expressed 1	0.069
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.069
CD86	CD86 molecule	0.068
MTA1	metastasis associated 1	0.068
MBD3	methyl-CpG binding domain protein 3	0.067
AR	androgen receptor	0.064
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.064
NUP62	nucleoporin 62kDa	0.064
DLL1	delta-like 1 (Drosophila)	0.064	Fly
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.063
XIAP	X-linked inhibitor of apoptosis	0.061
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.061
EEF2K	eukaryotic elongation factor-2 kinase	0.059
COASY	CoA synthase	0.059
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.058
STAG1	stromal antigen 1	0.057
RICTOR	RPTOR independent companion of MTOR, complex 2	0.056
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.056
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.056
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.055	Mouse
PTPN13	protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)	0.055
CDK9	cyclin-dependent kinase 9	0.055
EIF4ENIF1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.054
KIF2C	kinesin family member 2C	0.054
FBXO5	F-box protein 5	0.054
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.053
ANAPC11	anaphase promoting complex subunit 11	0.051
XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	0.051
CHD4	chromodomain helicase DNA binding protein 4	0.051
PRRC2C	proline-rich coiled-coil 2C	0.051
NRP1	neuropilin 1	0.051
TMPO	thymopoietin	0.050
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.050
PTEN	phosphatase and tensin homolog	0.050
MLF1IP	MLF1 interacting protein	0.049
AURKB	aurora kinase B	0.049
GATAD2B	GATA zinc finger domain containing 2B	0.049
CNOT7	CCR4-NOT transcription complex, subunit 7	0.049
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.048
IRS2	insulin receptor substrate 2	0.048
CDC45	cell division cycle 45 homolog (S. cerevisiae)	0.048	Fly
SARS	seryl-tRNA synthetase	0.048
DEK	DEK oncogene	0.048
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.047
AARS	alanyl-tRNA synthetase	0.047
SOX2	SRY (sex determining region Y)-box 2	0.047
CUL1	cullin 1	0.047
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.046
CNOT10	CCR4-NOT transcription complex, subunit 10	0.046
CIZ1	CDKN1A interacting zinc finger protein 1	0.046
IL2RB	interleukin 2 receptor, beta	0.045
SPDEF	SAM pointed domain containing ets transcription factor	0.045
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.045
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.044
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.044
SFPQ	splicing factor proline/glutamine-rich	0.043
ITGB1BP3	integrin beta 1 binding protein 3	0.043
CNOT1	CCR4-NOT transcription complex, subunit 1	0.043
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.043
CSNK1A1	casein kinase 1, alpha 1	0.043
CCNT1	cyclin T1	0.043
E2F3	E2F transcription factor 3	0.043
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.042
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.042
PPIG	peptidylprolyl isomerase G (cyclophilin G)	0.041
CAV2	caveolin 2	0.041
CUL2	cullin 2	0.041
COL2A1	collagen, type II, alpha 1	0.040
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.040
ZSWIM7	zinc finger, SWIM-type containing 7	0.040
SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5	0.039
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.039
TROAP	trophinin associated protein (tastin)	0.039
MCM4	minichromosome maintenance complex component 4	0.039
KDM5A	lysine (K)-specific demethylase 5A	0.038
UBE2C	ubiquitin-conjugating enzyme E2C	0.037
RFWD2	ring finger and WD repeat domain 2	0.037
HMGB1	high mobility group box 1	0.037
STAT5B	signal transducer and activator of transcription 5B	0.037	Mouse
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.037
JAG2	jagged 2	0.037
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.037
RANBP9	RAN binding protein 9	0.037
KRTAP4-12	keratin associated protein 4-12	0.037
ATXN1L	ataxin 1-like	0.036
HMGB2	high mobility group box 2	0.036
SUFU	suppressor of fused homolog (Drosophila)	0.036
NCOA2	nuclear receptor coactivator 2	0.036
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.036	Rat
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.035
PECAM1	platelet/endothelial cell adhesion molecule	0.035
ADRBK1	adrenergic, beta, receptor kinase 1	0.035
MED1	mediator complex subunit 1	0.035
MARK2	MAP/microtubule affinity-regulating kinase 2	0.035
FOXO1	forkhead box O1	0.035
THBS1	thrombospondin 1	0.034
POLQ	polymerase (DNA directed), theta	0.034
RPTOR	regulatory associated protein of MTOR, complex 1	0.034
TAL1	T-cell acute lymphocytic leukemia 1	0.034
CDK11B	cyclin-dependent kinase 11B	0.034
LIN54	lin-54 homolog (C. elegans)	0.034
PDX1	pancreatic and duodenal homeobox 1	0.034
RNF2	ring finger protein 2	0.033
ZNRF1	zinc and ring finger 1	0.033
RECQL4	RecQ protein-like 4	0.033
STAT5A	signal transducer and activator of transcription 5A	0.033	Mouse
MAPT	microtubule-associated protein tau	0.032
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.032
PDGFA	platelet-derived growth factor alpha polypeptide	0.032	Human
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.032
E2F2	E2F transcription factor 2	0.032
TINF2	TERF1 (TRF1)-interacting nuclear factor 2	0.031
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.031
WEE1	WEE1 homolog (S. pombe)	0.031
EPHA2	EPH receptor A2	0.031
HCFC1	host cell factor C1 (VP16-accessory protein)	0.031
MYOD1	myogenic differentiation 1	0.031
GATA2	GATA binding protein 2	0.030
RAPGEF6	Rap guanine nucleotide exchange factor (GEF) 6	0.030
EPRS	glutamyl-prolyl-tRNA synthetase	0.030
FGFR1	fibroblast growth factor receptor 1	0.029
CEP350	centrosomal protein 350kDa	0.029
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.029
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.029
IGFBP5	insulin-like growth factor binding protein 5	0.029
GATA4	GATA binding protein 4	0.029
NOTCH2NL	notch 2 N-terminal like	0.029
GHR	growth hormone receptor	0.028
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.028
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.028
PRKCE	protein kinase C, epsilon	0.028	Human
SCAF11	SR-related CTD-associated factor 11	0.028
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.028
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.028
RUNX1	runt-related transcription factor 1	0.028
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.028
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.028
RAD51AP1	RAD51 associated protein 1	0.028
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.028
TP53	tumor protein p53	0.027
RGS3	regulator of G-protein signaling 3	0.027
RAD52	RAD52 homolog (S. cerevisiae)	0.027
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.027
FGF3	fibroblast growth factor 3	0.027
BCAR1	breast cancer anti-estrogen resistance 1	0.027
EPOR	erythropoietin receptor	0.027
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.026
JMJD6	jumonji domain containing 6	0.026
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.026	Human
KRT15	keratin 15	0.026
SEC31A	SEC31 homolog A (S. cerevisiae)	0.026
SMAD4	SMAD family member 4	0.026
FEV	FEV (ETS oncogene family)	0.026
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.026
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.026
TGFA	transforming growth factor, alpha	0.025
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.025
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.025
FOXF2	forkhead box F2	0.025
MAP2K1	mitogen-activated protein kinase kinase 1	0.025
GATAD2A	GATA zinc finger domain containing 2A	0.025
EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2	0.025	Human
WNT3A	wingless-type MMTV integration site family, member 3A	0.025
PLAUR	plasminogen activator, urokinase receptor	0.025
CLTC	clathrin, heavy chain (Hc)	0.025
RRM2	ribonucleotide reductase M2	0.024
MTA2	metastasis associated 1 family, member 2	0.024
MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)	0.024
PRC1	protein regulator of cytokinesis 1	0.024
CREBBP	CREB binding protein	0.024	Rat
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.024
SPTBN4	spectrin, beta, non-erythrocytic 4	0.024
ANAPC1	anaphase promoting complex subunit 1	0.024
HELLS	helicase, lymphoid-specific	0.024
HMGA2	high mobility group AT-hook 2	0.024
SIRT2	sirtuin 2	0.024
DCN	decorin	0.023
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.023
MED12	mediator complex subunit 12	0.023
TOM1L1	target of myb1 (chicken)-like 1	0.023
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.023
ONECUT1	one cut homeobox 1	0.023
H1F0	H1 histone family, member 0	0.023
CDK14	cyclin-dependent kinase 14	0.023
EGF	epidermal growth factor	0.023
UBXN7	UBX domain protein 7	0.023
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.023
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.023
SLA	Src-like-adaptor	0.023
FOXB1	forkhead box B1	0.023
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.023
UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)	0.023
KIF23	kinesin family member 23	0.023
CNOT8	CCR4-NOT transcription complex, subunit 8	0.022
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.022
LTK	leukocyte receptor tyrosine kinase	0.022	Human
ZCCHC8	zinc finger, CCHC domain containing 8	0.022
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.022
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.022	Fly
TNIP2	TNFAIP3 interacting protein 2	0.022
CCNA1	cyclin A1	0.022
ARHGAP26	Rho GTPase activating protein 26	0.022
PLK4	polo-like kinase 4	0.022
CHFR	checkpoint with forkhead and ring finger domains	0.022
NGFR	nerve growth factor receptor	0.022
IL1B	interleukin 1, beta	0.022
CAPRIN2	caprin family member 2	0.022
ORC6	origin recognition complex, subunit 6	0.022
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.022
MAF1	MAF1 homolog (S. cerevisiae)	0.022
MESDC2	mesoderm development candidate 2	0.022
EIF4E	eukaryotic translation initiation factor 4E	0.021
MIS18BP1	MIS18 binding protein 1	0.021
PTPRR	protein tyrosine phosphatase, receptor type, R	0.021
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.021
PTTG1	pituitary tumor-transforming 1	0.021
STIL	SCL/TAL1 interrupting locus	0.021
BCL2	B-cell CLL/lymphoma 2	0.021
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.021
TUBA1A	tubulin, alpha 1a	0.021
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.021
ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	0.021
MNX1	motor neuron and pancreas homeobox 1	0.021
HOXD12	homeobox D12	0.021
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.021
FAM64A	family with sequence similarity 64, member A	0.020
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.020
INHBB	inhibin, beta B	0.020
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.020
TIMELESS	timeless homolog (Drosophila)	0.020
RBBP8	retinoblastoma binding protein 8	0.020
MIB1	mindbomb homolog 1 (Drosophila)	0.020
WDR76	WD repeat domain 76	0.020
POU4F2	POU class 4 homeobox 2	0.020
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.020
PDS5B	PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)	0.020
DCAF15	DDB1 and CUL4 associated factor 15	0.020
FZD5	frizzled homolog 5 (Drosophila)	0.020
CENPF	centromere protein F, 350/400kDa (mitosin)	0.020
HDAC6	histone deacetylase 6	0.020
DUSP7	dual specificity phosphatase 7	0.020
HOXD13	homeobox D13	0.020
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.020
ACAN	aggrecan	0.020
GSK3B	glycogen synthase kinase 3 beta	0.019	Fly
CDX2	caudal type homeobox 2	0.019
TGFB2	transforming growth factor, beta 2	0.019
KIFC1	kinesin family member C1	0.019
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.019
CELF1	CUGBP, Elav-like family member 1	0.019	Fly
HOXC8	homeobox C8	0.019
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.019
CEP110	centrosomal protein 110kDa	0.019
KPNB1	karyopherin (importin) beta 1	0.019
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.019
HOXA11	homeobox A11	0.019
PHOX2A	paired-like homeobox 2a	0.019
SON	SON DNA binding protein	0.019
CDK13	cyclin-dependent kinase 13	0.019
CDCA4	cell division cycle associated 4	0.019
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.019
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.019
FRS2	fibroblast growth factor receptor substrate 2	0.019
PTPRB	protein tyrosine phosphatase, receptor type, B	0.019
IRS4	insulin receptor substrate 4	0.019
DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	0.019
LSM6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.019
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.019
ZNF367	zinc finger protein 367	0.019
TP73	tumor protein p73	0.019
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.019
SUDS3	suppressor of defective silencing 3 homolog (S. cerevisiae)	0.018
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.018
NEUROG1	neurogenin 1	0.018	Human Mouse
SPRR2D	small proline-rich protein 2D	0.018
CHD3	chromodomain helicase DNA binding protein 3	0.018
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.018
ATAD2	ATPase family, AAA domain containing 2	0.018
INCENP	inner centromere protein antigens 135/155kDa	0.018
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.018
LST1	leukocyte specific transcript 1	0.018
SMC4	structural maintenance of chromosomes 4	0.018
STAMBP	STAM binding protein	0.018
PITX2	paired-like homeodomain 2	0.018
SOX11	SRY (sex determining region Y)-box 11	0.018
CHMP1B	chromatin modifying protein 1B	0.018
FOXC1	forkhead box C1	0.018	Human
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.018
YARS	tyrosyl-tRNA synthetase	0.018
RING1	ring finger protein 1	0.018
USP20	ubiquitin specific peptidase 20	0.018
LMO4	LIM domain only 4	0.018
APP	amyloid beta (A4) precursor protein	0.018	Mouse
CD33	CD33 molecule	0.017
BACE1	beta-site APP-cleaving enzyme 1	0.017
KNTC1	kinetochore associated 1	0.017
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.017
DBF4	DBF4 homolog (S. cerevisiae)	0.017
RNF19A	ring finger protein 19A	0.017
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.017
FOXA2	forkhead box A2	0.017	Human
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.017
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.017
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.017
CCDC85B	coiled-coil domain containing 85B	0.017
WDR48	WD repeat domain 48	0.017
C19orf46	chromosome 19 open reading frame 46	0.017
SIX6	SIX homeobox 6	0.017
BTG2	BTG family, member 2	0.017
E2F5	E2F transcription factor 5, p130-binding	0.017
RAD54L	RAD54-like (S. cerevisiae)	0.017
SATB1	SATB homeobox 1	0.017
CBX8	chromobox homolog 8	0.017
PTPRF	protein tyrosine phosphatase, receptor type, F	0.017
CUX1	cut-like homeobox 1	0.017
NEIL3	nei endonuclease VIII-like 3 (E. coli)	0.017
MPP1	membrane protein, palmitoylated 1, 55kDa	0.017
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.017
NBR1	neighbor of BRCA1 gene 1	0.016
SGOL1	shugoshin-like 1 (S. pombe)	0.016
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.016
MBD2	methyl-CpG binding domain protein 2	0.016
PAX7	paired box 7	0.016
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.016
PIM1	pim-1 oncogene	0.016
AHNAK	AHNAK nucleoprotein	0.016
LRRK2	leucine-rich repeat kinase 2	0.016
ZNF746	zinc finger protein 746	0.016
TLX1	T-cell leukemia homeobox 1	0.016
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.016
FAM193B	family with sequence similarity 193, member B	0.016
TTK	TTK protein kinase	0.016
TCP1	t-complex 1	0.016
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.016
CDK12	cyclin-dependent kinase 12	0.016
USP22	ubiquitin specific peptidase 22	0.016
RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)	0.016
WDR26	WD repeat domain 26	0.016
SOX9	SRY (sex determining region Y)-box 9	0.016
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.016
VCP	valosin containing protein	0.016
KRT1	keratin 1	0.016
KIF14	kinesin family member 14	0.016
IGF2	insulin-like growth factor 2 (somatomedin A)	0.016
HOXD11	homeobox D11	0.016
MCM3	minichromosome maintenance complex component 3	0.016
POLR2K	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	0.016
MAK	male germ cell-associated kinase	0.016
MCM2	minichromosome maintenance complex component 2	0.016
HOXD9	homeobox D9	0.016
SMC1A	structural maintenance of chromosomes 1A	0.016
NSMCE2	non-SMC element 2, MMS21 homolog (S. cerevisiae)	0.016
PID1	phosphotyrosine interaction domain containing 1	0.016
STAP2	signal transducing adaptor family member 2	0.016
TOP3A	topoisomerase (DNA) III alpha	0.016
KRT17	keratin 17	0.015
CALCR	calcitonin receptor	0.015
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.015
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.015	Human
SKA1	spindle and kinetochore associated complex subunit 1	0.015
NKD2	naked cuticle homolog 2 (Drosophila)	0.015
MCM7	minichromosome maintenance complex component 7	0.015
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.015
STMN1	stathmin 1	0.015
MEF2C	myocyte enhancer factor 2C	0.015
STC1	stanniocalcin 1	0.015
RBBP6	retinoblastoma binding protein 6	0.015
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.015
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.015
NFIB	nuclear factor I/B	0.015
FCN2	ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)	0.015
NKX6-1	NK6 homeobox 1	0.015
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.015
USP1	ubiquitin specific peptidase 1	0.015
TNFRSF21	tumor necrosis factor receptor superfamily, member 21	0.015
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	0.015
PKM2	pyruvate kinase, muscle	0.015
IL1RN	interleukin 1 receptor antagonist	0.015	Human
TCF15	transcription factor 15 (basic helix-loop-helix)	0.015	Human
NPEPPS	aminopeptidase puromycin sensitive	0.015
SIX2	SIX homeobox 2	0.015
DTL	denticleless homolog (Drosophila)	0.015
SOX4	SRY (sex determining region Y)-box 4	0.015
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.015
RAD9A	RAD9 homolog A (S. pombe)	0.015
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.015	Yeast
TCF12	transcription factor 12	0.015
LDLR	low density lipoprotein receptor	0.015
CARS	cysteinyl-tRNA synthetase	0.015
HEXA	hexosaminidase A (alpha polypeptide)	0.015
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.015
PRNP	prion protein	0.015
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.015
SERTAD4	SERTA domain containing 4	0.015
PDCD7	programmed cell death 7	0.015
DUSP5	dual specificity phosphatase 5	0.015
SOX18	SRY (sex determining region Y)-box 18	0.015
CAND1	cullin-associated and neddylation-dissociated 1	0.015
FOSL1	FOS-like antigen 1	0.015
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.015
HNF1B	HNF1 homeobox B	0.015
SKA2	spindle and kinetochore associated complex subunit 2	0.015
EGFL7	EGF-like-domain, multiple 7	0.015
HDAC2	histone deacetylase 2	0.015
FGF8	fibroblast growth factor 8 (androgen-induced)	0.015
ORC5	origin recognition complex, subunit 5	0.014
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.014
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.014
RNF220	ring finger protein 220	0.014
ANAPC7	anaphase promoting complex subunit 7	0.014
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.014
EIF3C	eukaryotic translation initiation factor 3, subunit C	0.014
LMNB1	lamin B1	0.014
HMX1	H6 family homeobox 1	0.014
APOE	apolipoprotein E	0.014
HOXB9	homeobox B9	0.014
SIPA1	signal-induced proliferation-associated 1	0.014
DTNBP1	dystrobrevin binding protein 1	0.014
MSH5	mutS homolog 5 (E. coli)	0.014
SETD5	SET domain containing 5	0.014
AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	0.014
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.014	Human Fly
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.014
BTBD2	BTB (POZ) domain containing 2	0.014
LYL1	lymphoblastic leukemia derived sequence 1	0.014	Human
KIF5B	kinesin family member 5B	0.014
FZD10	frizzled homolog 10 (Drosophila)	0.014
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.014
NPAT	nuclear protein, ataxia-telangiectasia locus	0.014
CASK	calcium/calmodulin-dependent serine protein kinase (MAGUK family)	0.014
NOV	nephroblastoma overexpressed gene	0.014
NKAP	NFKB activating protein	0.014
NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1	0.014
NKX2-1	NK2 homeobox 1	0.014
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.014
SMAD6	SMAD family member 6	0.014
CBX4	chromobox homolog 4	0.014
SOX1	SRY (sex determining region Y)-box 1	0.014
RARG	retinoic acid receptor, gamma	0.014
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.014
DCLRE1B	DNA cross-link repair 1B	0.014
RNF126	ring finger protein 126	0.014
DLX2	distal-less homeobox 2	0.014
SFRP5	secreted frizzled-related protein 5	0.014
NKX2-8	NK2 homeobox 8	0.014
AES	amino-terminal enhancer of split	0.014
TBX2	T-box 2	0.014
PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)	0.014
CDCA3	cell division cycle associated 3	0.014
SRA1	steroid receptor RNA activator 1	0.014
AXIN1	axin 1	0.014
KRT14	keratin 14	0.014
NKX3-1	NK3 homeobox 1	0.014
APC	adenomatous polyposis coli	0.014
HOMER3	homer homolog 3 (Drosophila)	0.014
FBXO38	F-box protein 38	0.014
TGFBR1	transforming growth factor, beta receptor 1	0.014
LARP7	La ribonucleoprotein domain family, member 7	0.014	Mouse
HIST1H4F	histone cluster 1, H4f	0.014
RARA	retinoic acid receptor, alpha	0.014
SPOP	speckle-type POZ protein	0.013
CMIP	c-Maf-inducing protein	0.013
LHX5	LIM homeobox 5	0.013
BBX	bobby sox homolog (Drosophila)	0.013
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.013
NLK	nemo-like kinase	0.013
MYH10	myosin, heavy chain 10, non-muscle	0.013
SIM2	single-minded homolog 2 (Drosophila)	0.013
PRUNE	prune homolog (Drosophila)	0.013
TBX5	T-box 5	0.013
KDM2A	lysine (K)-specific demethylase 2A	0.013
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.013	Human
TRIM33	tripartite motif containing 33	0.013
ENG	endoglin	0.013
ITGB8	integrin, beta 8	0.013
TRIB3	tribbles homolog 3 (Drosophila)	0.013
SLC7A5	solute carrier family 7 (cationic amino acid transporter, y+ system), member 5	0.013
RNF8	ring finger protein 8	0.013
IER3	immediate early response 3	0.013
ZFR	zinc finger RNA binding protein	0.013
TEKT4	tektin 4	0.013
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.013
VASP	vasodilator-stimulated phosphoprotein	0.013
HOXA10	homeobox A10	0.013
IRX4	iroquois homeobox 4	0.013
MAP2K4	mitogen-activated protein kinase kinase 4	0.013
FZD8	frizzled homolog 8 (Drosophila)	0.013
SMS	spermine synthase	0.013
LRRN2	leucine rich repeat neuronal 2	0.013
ANKRD11	ankyrin repeat domain 11	0.013
KIF11	kinesin family member 11	0.013
SCNM1	sodium channel modifier 1	0.013
ZNF358	zinc finger protein 358	0.013
HAND2	heart and neural crest derivatives expressed 2	0.013	Human
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.013
FANCG	Fanconi anemia, complementation group G	0.013
HOXB13	homeobox B13	0.013
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.013
CENPJ	centromere protein J	0.013
MARS	methionyl-tRNA synthetase	0.013
DCUN1D2	DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)	0.013
CNOT3	CCR4-NOT transcription complex, subunit 3	0.013
RPL23	ribosomal protein L23	0.013
PLCG1	phospholipase C, gamma 1	0.013
PAX1	paired box 1	0.013
GPSM2	G-protein signaling modulator 2	0.013
ALX4	ALX homeobox 4	0.013
PPP5C	protein phosphatase 5, catalytic subunit	0.013
CRELD2	cysteine-rich with EGF-like domains 2	0.013
IGFBP1	insulin-like growth factor binding protein 1	0.013
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.013
NUP153	nucleoporin 153kDa	0.013
C1QL1	complement component 1, q subcomponent-like 1	0.013
HEXIM1	hexamethylene bis-acetamide inducible 1	0.013
HOXC13	homeobox C13	0.013
CBX7	chromobox homolog 7	0.013
DNA2	DNA replication helicase 2 homolog (yeast)	0.013
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	0.013	Human
PDGFC	platelet derived growth factor C	0.013
SYN2	synapsin II	0.013
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.013
NEUROD1	neurogenic differentiation 1	0.013	Human
NXPH4	neurexophilin 4	0.013
AP1M1	adaptor-related protein complex 1, mu 1 subunit	0.013
ARX	aristaless related homeobox	0.013
ZNF500	zinc finger protein 500	0.013
PAX6	paired box 6	0.013
NEUROG3	neurogenin 3	0.013	Human
KIF18B	kinesin family member 18B	0.013
ECT2	epithelial cell transforming sequence 2 oncogene	0.013
PSRC1	proline/serine-rich coiled-coil 1	0.013
ASXL2	additional sex combs like 2 (Drosophila)	0.013
MUC1	mucin 1, cell surface associated	0.013
SEMA6D	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D	0.013
BNC1	basonuclin 1	0.013
RNF11	ring finger protein 11	0.013
VAX1	ventral anterior homeobox 1	0.013
DLX4	distal-less homeobox 4	0.013	Human
HNF4A	hepatocyte nuclear factor 4, alpha	0.013
NNAT	neuronatin	0.013
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.013
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.013
PDPK1	3-phosphoinositide dependent protein kinase-1	0.013
MAP2K2	mitogen-activated protein kinase kinase 2	0.013
CCL20	chemokine (C-C motif) ligand 20	0.012
GAS2L3	growth arrest-specific 2 like 3	0.012
DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)	0.012
TMEM194A	transmembrane protein 194A	0.012
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.012
HAND1	heart and neural crest derivatives expressed 1	0.012	Human
CLIP1	CAP-GLY domain containing linker protein 1	0.012
NOTCH4	notch 4	0.012	Fly
GLI2	GLI family zinc finger 2	0.012	Fly
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.012
FOXL1	forkhead box L1	0.012	Human
COL1A1	collagen, type I, alpha 1	0.012
SUZ12	suppressor of zeste 12 homolog (Drosophila)	0.012
USF2	upstream transcription factor 2, c-fos interacting	0.012
SNAI1	snail homolog 1 (Drosophila)	0.012
VAX2	ventral anterior homeobox 2	0.012
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.012
IL11	interleukin 11	0.012
KLHL23	kelch-like 23 (Drosophila)	0.012
ZNF775	zinc finger protein 775	0.012
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.012
ARID3C	AT rich interactive domain 3C (BRIGHT-like)	0.012
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.012
H1FX	H1 histone family, member X	0.012
HIPK1	homeodomain interacting protein kinase 1	0.012
PHGDH	phosphoglycerate dehydrogenase	0.012
DUSP9	dual specificity phosphatase 9	0.012
CUL5	cullin 5	0.012
NOS1	nitric oxide synthase 1 (neuronal)	0.012
STK24	serine/threonine kinase 24	0.012
C6orf136	chromosome 6 open reading frame 136	0.012
SCARF2	scavenger receptor class F, member 2	0.012
EN2	engrailed homeobox 2	0.012
FOXF1	forkhead box F1	0.012
HMGN2	high mobility group nucleosomal binding domain 2	0.012
CLCF1	cardiotrophin-like cytokine factor 1	0.012
KIF20B	kinesin family member 20B	0.012
LRP1	low density lipoprotein receptor-related protein 1	0.012	Human
GPSM3	G-protein signaling modulator 3	0.012
KIAA0467	KIAA0467	0.012
WNT6	wingless-type MMTV integration site family, member 6	0.012
PPP6R3	protein phosphatase 6, regulatory subunit 3	0.012
THOC2	THO complex 2	0.012
IHH	Indian hedgehog	0.012
PSEN1	presenilin 1	0.012
CSTA	cystatin A (stefin A)	0.012
LHX3	LIM homeobox 3	0.012
STRN4	striatin, calmodulin binding protein 4	0.012
GDNF	glial cell derived neurotrophic factor	0.012
CARD11	caspase recruitment domain family, member 11	0.012
SORBS3	sorbin and SH3 domain containing 3	0.012
PTHLH	parathyroid hormone-like hormone	0.012
EPHB4	EPH receptor B4	0.012
DLL4	delta-like 4 (Drosophila)	0.012	Fly
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.012
MELK	maternal embryonic leucine zipper kinase	0.012
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.012
TRIM39	tripartite motif containing 39	0.012
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.012
CD52	CD52 molecule	0.012
TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	0.012
ANKRD28	ankyrin repeat domain 28	0.012
PLD1	phospholipase D1, phosphatidylcholine-specific	0.012
KIF18A	kinesin family member 18A	0.012
POU4F3	POU class 4 homeobox 3	0.012
NOP10	NOP10 ribonucleoprotein homolog (yeast)	0.012
CASC5	cancer susceptibility candidate 5	0.012
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.012
PAX2	paired box 2	0.012
BEND5	BEN domain containing 5	0.012