IMP: Integrative Multi-species Prediction

Homo sapiens

1 genes annotated in human

Multi-species View

negative regulation of interleukin 13 secretion

GO:2000666

Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-13 secretion.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of interleukin 13 secretion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of interleukin 13 secretion" (in gray)

Name	Description	Probability	Func Analog Organism
SNAP23	synaptosomal-associated protein, 23kDa	0.993
IFNA4	interferon, alpha 4	0.881
IFNA21	interferon, alpha 21	0.692	Human
IFNA17	interferon, alpha 17	0.677
IFNA16	interferon, alpha 16	0.616	Human
IFNA10	interferon, alpha 10	0.552	Human
IFNA14	interferon, alpha 14	0.544
APP	amyloid beta (A4) precursor protein	0.520
IFNA7	interferon, alpha 7	0.330	Human
TAS2R16	taste receptor, type 2, member 16	0.249
CYLC1	cylicin, basic protein of sperm head cytoskeleton 1	0.243
IFNA13	interferon, alpha 13	0.206
COLEC10	collectin sub-family member 10 (C-type lectin)	0.139
C6orf10	chromosome 6 open reading frame 10	0.132
GYPB	glycophorin B (MNS blood group)	0.080
HTN1	histatin 1	0.070
IFNA2	interferon, alpha 2	0.067
OR7A10	olfactory receptor, family 7, subfamily A, member 10	0.064
OR2B2	olfactory receptor, family 2, subfamily B, member 2	0.064
TAS2R7	taste receptor, type 2, member 7	0.061
AFM	afamin	0.055
CTAGE1	cutaneous T-cell lymphoma-associated antigen 1	0.055
HTN3	histatin 3	0.054
TSHB	thyroid stimulating hormone, beta	0.054
IAPP	islet amyloid polypeptide	0.052
CYLC2	cylicin, basic protein of sperm head cytoskeleton 2	0.050
STAT5A	signal transducer and activator of transcription 5A	0.050
IFNA8	interferon, alpha 8	0.049	Human
GYPA	glycophorin A (MNS blood group)	0.049
OR52A1	olfactory receptor, family 52, subfamily A, member 1	0.049
CSN1S1	casein alpha s1	0.048
RRH	retinal pigment epithelium-derived rhodopsin homolog	0.048
IFNA5	interferon, alpha 5	0.046	Human
FGL1	fibrinogen-like 1	0.046
STATH	statherin	0.044
ANGPTL3	angiopoietin-like 3	0.041
TRIM48	tripartite motif containing 48	0.040
SPO11	SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)	0.040
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.040
SEMG2	semenogelin II	0.039
LIPF	lipase, gastric	0.038
STX11	syntaxin 11	0.037
LUZP4	leucine zipper protein 4	0.036
IL21	interleukin 21	0.035
PDC	phosducin	0.034
PSMD5	proteasome (prosome, macropain) 26S subunit, non-ATPase, 5	0.033
CRISP1	cysteine-rich secretory protein 1	0.032
GNAT2	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2	0.032
TAS2R8	taste receptor, type 2, member 8	0.032
CLDN17	claudin 17	0.032
CYP2C19	cytochrome P450, family 2, subfamily C, polypeptide 19	0.032
CSN3	casein kappa	0.031
SLCO1B1	solute carrier organic anion transporter family, member 1B1	0.028
RGSL1	regulator of G-protein signaling like 1	0.028
FSHR	follicle stimulating hormone receptor	0.028
HNF4G	hepatocyte nuclear factor 4, gamma	0.027
ODAM	odontogenic, ameloblast asssociated	0.027
CSN2	casein beta	0.027
HIST1H3J	histone cluster 1, H3j	0.027
GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2	0.026
FABP2	fatty acid binding protein 2, intestinal	0.026
TAAR2	trace amine associated receptor 2	0.026
F13B	coagulation factor XIII, B polypeptide	0.025
GPR22	G protein-coupled receptor 22	0.025
SNTG1	syntrophin, gamma 1	0.024
CYP7A1	cytochrome P450, family 7, subfamily A, polypeptide 1	0.024
MTMR7	myotubularin related protein 7	0.024
KRTAP1-1	keratin associated protein 1-1	0.023
NMBR	neuromedin B receptor	0.023
CNGB3	cyclic nucleotide gated channel beta 3	0.023
CDH9	cadherin 9, type 2 (T1-cadherin)	0.023
GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.023
C1orf129	chromosome 1 open reading frame 129	0.023
GYPE	glycophorin E (MNS blood group)	0.023
PDE6H	phosphodiesterase 6H, cGMP-specific, cone, gamma	0.022
OMG	oligodendrocyte myelin glycoprotein	0.022
MORC1	MORC family CW-type zinc finger 1	0.022
IMPG2	interphotoreceptor matrix proteoglycan 2	0.022
HYAL4	hyaluronoglucosaminidase 4	0.022
SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	0.022
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.022
ANP32C	acidic (leucine-rich) nuclear phosphoprotein 32 family, member C	0.021
TNFSF18	tumor necrosis factor (ligand) superfamily, member 18	0.021
ADAM2	ADAM metallopeptidase domain 2	0.021
ART4	ADP-ribosyltransferase 4 (Dombrock blood group)	0.021
PMP2	peripheral myelin protein 2	0.021
HESX1	HESX homeobox 1	0.021
ZNF81	zinc finger protein 81	0.021
KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	0.021
CTNNA3	catenin (cadherin-associated protein), alpha 3	0.020
TM4SF20	transmembrane 4 L six family member 20	0.020
ANXA10	annexin A10	0.020
GNRHR	gonadotropin-releasing hormone receptor	0.020
ZNF157	zinc finger protein 157	0.020
MS4A5	membrane-spanning 4-domains, subfamily A, member 5	0.020
IFNA6	interferon, alpha 6	0.020	Human
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.020
PLSCR2	phospholipid scramblase 2	0.020
PLAC1	placenta-specific 1	0.020
LECT2	leukocyte cell-derived chemotaxin 2	0.020
ASCL3	achaete-scute complex homolog 3 (Drosophila)	0.020
GCG	glucagon	0.020
LHCGR	luteinizing hormone/choriogonadotropin receptor	0.019
TRPC7	transient receptor potential cation channel, subfamily C, member 7	0.019
KRTAP2-4	keratin associated protein 2-4	0.019
LALBA	lactalbumin, alpha-	0.019
PSG2	pregnancy specific beta-1-glycoprotein 2	0.018
IL1RAPL1	interleukin 1 receptor accessory protein-like 1	0.018
NTS	neurotensin	0.018
SI	sucrase-isomaltase (alpha-glucosidase)	0.018
OR5P2	olfactory receptor, family 5, subfamily P, member 2	0.018
ALX1	ALX homeobox 1	0.018
S100G	S100 calcium binding protein G	0.018
ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6	0.018
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.018
SCN11A	sodium channel, voltage-gated, type XI, alpha subunit	0.018
PDE6C	phosphodiesterase 6C, cGMP-specific, cone, alpha prime	0.017
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.017
EPYC	epiphycan	0.017
IL2	interleukin 2	0.017
OR1D2	olfactory receptor, family 1, subfamily D, member 2	0.017
C10orf68	chromosome 10 open reading frame 68	0.017
SLCO1B3	solute carrier organic anion transporter family, member 1B3	0.017
INSL4	insulin-like 4 (placenta)	0.017
B3GALT1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	0.017
SERPINB10	serpin peptidase inhibitor, clade B (ovalbumin), member 10	0.017
GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	0.017
SSX3	synovial sarcoma, X breakpoint 3	0.016
OR5I1	olfactory receptor, family 5, subfamily I, member 1	0.016
TMEM212	transmembrane protein 212	0.016
PRAMEF2	PRAME family member 2	0.016
TEX12	testis expressed 12	0.016
SPRR2B	small proline-rich protein 2B	0.016
GLRA3	glycine receptor, alpha 3	0.016
RFPL1	ret finger protein-like 1	0.016
BPY2	basic charge, Y-linked, 2	0.016
CCDC54	coiled-coil domain containing 54	0.016
SERPINI2	serpin peptidase inhibitor, clade I (pancpin), member 2	0.016
AADAC	arylacetamide deacetylase (esterase)	0.015
AOC2	amine oxidase, copper containing 2 (retina-specific)	0.015
OLAH	oleoyl-ACP hydrolase	0.015
HRH4	histamine receptor H4	0.015
TMPRSS11B	transmembrane protease, serine 11B	0.015
PSG11	pregnancy specific beta-1-glycoprotein 11	0.015
ZNF816	zinc finger protein 816	0.015
KERA	keratocan	0.015
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.015
RLN1	relaxin 1	0.015
GPRC6A	G protein-coupled receptor, family C, group 6, member A	0.015
ZNF280A	zinc finger protein 280A	0.015
AMELY	amelogenin, Y-linked	0.015
ZNF221	zinc finger protein 221	0.015
PCDHGB6	protocadherin gamma subfamily B, 6	0.015
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.015
GPR75	G protein-coupled receptor 75	0.015
TAS2R9	taste receptor, type 2, member 9	0.015
SPINK1	serine peptidase inhibitor, Kazal type 1	0.015
CLDN16	claudin 16	0.015
SPIN2A	spindlin family, member 2A	0.014
ACCN5	amiloride-sensitive cation channel 5, intestinal	0.014
FLG	filaggrin	0.014
PTH	parathyroid hormone	0.014
CFHR5	complement factor H-related 5	0.014
MC4R	melanocortin 4 receptor	0.014
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.014
MLANA	melan-A	0.014
MMP27	matrix metallopeptidase 27	0.014
OR7A17	olfactory receptor, family 7, subfamily A, member 17	0.014
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.014
CD4	CD4 molecule	0.014
PRG4	proteoglycan 4	0.014
ANP32D	acidic (leucine-rich) nuclear phosphoprotein 32 family, member D	0.014
ADPRH	ADP-ribosylarginine hydrolase	0.014
UGT1A7	UDP glucuronosyltransferase 1 family, polypeptide A7	0.014
ROS1	c-ros oncogene 1 , receptor tyrosine kinase	0.014
SULT1B1	sulfotransferase family, cytosolic, 1B, member 1	0.013
SMR3B	submaxillary gland androgen regulated protein 3B	0.013
NEU3	sialidase 3 (membrane sialidase)	0.013
CRYGB	crystallin, gamma B	0.013
PSG3	pregnancy specific beta-1-glycoprotein 3	0.013
PBOV1	prostate and breast cancer overexpressed 1	0.013
KLHL4	kelch-like 4 (Drosophila)	0.013
IL26	interleukin 26	0.013
IFNB1	interferon, beta 1, fibroblast	0.013	Human
DPPA4	developmental pluripotency associated 4	0.013
TAS2R4	taste receptor, type 2, member 4	0.013
SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	0.013
TMPRSS15	transmembrane protease, serine 15	0.013
PRKG2	protein kinase, cGMP-dependent, type II	0.013
GARNL3	GTPase activating Rap/RanGAP domain-like 3	0.013
SLCO1A2	solute carrier organic anion transporter family, member 1A2	0.013
OCLM	oculomedin	0.013
CST1	cystatin SN	0.012
MIA2	melanoma inhibitory activity 2	0.012
KRTAP4-7	keratin associated protein 4-7	0.012
MTMR8	myotubularin related protein 8	0.012
ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3	0.012
DEFB126	defensin, beta 126	0.012
C11orf40	chromosome 11 open reading frame 40	0.012
ARG1	arginase, liver	0.012
ADAM29	ADAM metallopeptidase domain 29	0.012
SMR3A	submaxillary gland androgen regulated protein 3A	0.012
C12orf39	chromosome 12 open reading frame 39	0.012
CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8	0.012
RNF17	ring finger protein 17	0.012
LGSN	lengsin, lens protein with glutamine synthetase domain	0.012
LPAR4	lysophosphatidic acid receptor 4	0.012
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.012
RXFP2	relaxin/insulin-like family peptide receptor 2	0.012
KIF24	kinesin family member 24	0.012
PTTG2	pituitary tumor-transforming 2	0.012
OPN5	opsin 5	0.012
SMCP	sperm mitochondria-associated cysteine-rich protein	0.012
AMPD1	adenosine monophosphate deaminase 1	0.012
TSGA13	testis specific, 13	0.012
SLC13A1	solute carrier family 13 (sodium/sulfate symporters), member 1	0.012
RNF133	ring finger protein 133	0.011
ADAM21	ADAM metallopeptidase domain 21	0.011
SEMG1	semenogelin I	0.011
TAS2R3	taste receptor, type 2, member 3	0.011
MCF2	MCF.2 cell line derived transforming sequence	0.011
LGALS13	lectin, galactoside-binding, soluble, 13	0.011
BAGE	B melanoma antigen	0.011
TEX15	testis expressed 15	0.011
GABRB1	gamma-aminobutyric acid (GABA) A receptor, beta 1	0.011
TAAR1	trace amine associated receptor 1	0.011
AKAP4	A kinase (PRKA) anchor protein 4	0.011
TMPRSS11E	transmembrane protease, serine 11E	0.011
CA1	carbonic anhydrase I	0.011
OPHN1	oligophrenin 1	0.011
HIST1H4F	histone cluster 1, H4f	0.011
SLC25A21	solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21	0.011
ZBBX	zinc finger, B-box domain containing	0.011
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.011
EDDM3B	epididymal protein 3B	0.011
SPATA16	spermatogenesis associated 16	0.011
C9	complement component 9	0.011
NDST4	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4	0.011
TACR3	tachykinin receptor 3	0.011
TIGD6	tigger transposable element derived 6	0.011
VIP	vasoactive intestinal peptide	0.011
AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)	0.011
IL4	interleukin 4	0.011
AFP	alpha-fetoprotein	0.011
FGB	fibrinogen beta chain	0.011
TXNDC3	thioredoxin domain containing 3 (spermatozoa)	0.011
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.011
SERPINB13	serpin peptidase inhibitor, clade B (ovalbumin), member 13	0.011
CCL1	chemokine (C-C motif) ligand 1	0.011
PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2	0.011
CFHR4	complement factor H-related 4	0.011
SLC22A13	solute carrier family 22 (organic anion transporter), member 13	0.011
SCN2A	sodium channel, voltage-gated, type II, alpha subunit	0.011
IFNA1	interferon, alpha 1	0.011	Human
TEX11	testis expressed 11	0.011
STARD6	StAR-related lipid transfer (START) domain containing 6	0.010
CDH12	cadherin 12, type 2 (N-cadherin 2)	0.010
PCDHB8	protocadherin beta 8	0.010
TAS2R10	taste receptor, type 2, member 10	0.010
ADAM18	ADAM metallopeptidase domain 18	0.010
KRT12	keratin 12	0.010
IL22	interleukin 22	0.010
SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7	0.010
CLEC1B	C-type lectin domain family 1, member B	0.010
CPA2	carboxypeptidase A2 (pancreatic)	0.010
MSTN	myostatin	0.010
DNASE2B	deoxyribonuclease II beta	0.010
C1orf105	chromosome 1 open reading frame 105	0.010
ZKSCAN3	zinc finger with KRAB and SCAN domains 3	0.010
KIR2DS3	killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 3	0.010
TRIM10	tripartite motif containing 10	0.010
IL10	interleukin 10	0.010
FGA	fibrinogen alpha chain	0.010
PRDM5	PR domain containing 5	0.010
SLC25A31	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31	0.010
HAVCR1	hepatitis A virus cellular receptor 1	0.010