IMP: Integrative Multi-species Prediction

Homo sapiens

12 genes annotated in human

t cell apoptotic process

Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "t cell apoptotic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "t cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
CASP8	caspase 8, apoptosis-related cysteine peptidase	1.000	Mouse
CFLAR	CASP8 and FADD-like apoptosis regulator	0.986
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.960
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.954
FAS	Fas (TNF receptor superfamily, member 6)	0.937	Mouse
FADD	Fas (TNFRSF6)-associated via death domain	0.935	Mouse
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.858
BCL2	B-cell CLL/lymphoma 2	0.742
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.633
CCR5	chemokine (C-C motif) receptor 5	0.599
BAK1	BCL2-antagonist/killer 1	0.490
BMPR1A	bone morphogenetic protein receptor, type IA	0.462
NOXA1	NADPH oxidase activator 1	0.458
DFFB	DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)	0.363
BAX	BCL2-associated X protein	0.329	Mouse
BID	BH3 interacting domain death agonist	0.293
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.275	Mouse
PRKCZ	protein kinase C, zeta	0.255	Human
CALCOCO2	calcium binding and coiled-coil domain 2	0.246
BCL2L1	BCL2-like 1	0.243
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.214
FASLG	Fas ligand (TNF superfamily, member 6)	0.194
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.159
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.153
TRAF1	TNF receptor-associated factor 1	0.152
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.151
CXCL2	chemokine (C-X-C motif) ligand 2	0.132
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.127
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.127	Human
CCL4	chemokine (C-C motif) ligand 4	0.118	Human
CCL2	chemokine (C-C motif) ligand 2	0.114	Human
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.104
TGIF1	TGFB-induced factor homeobox 1	0.079
FSTL1	follistatin-like 1	0.078
SQSTM1	sequestosome 1	0.077
CCL5	chemokine (C-C motif) ligand 5	0.072
BRCA1	breast cancer 1, early onset	0.065
CCL13	chemokine (C-C motif) ligand 13	0.060	Human
CCL3	chemokine (C-C motif) ligand 3	0.057	Human
IDE	insulin-degrading enzyme	0.057
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.056
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.055
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.051
CARD11	caspase recruitment domain family, member 11	0.051
C9orf89	chromosome 9 open reading frame 89	0.050
CCR7	chemokine (C-C motif) receptor 7	0.050
CCL8	chemokine (C-C motif) ligand 8	0.047	Human
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.046
CXCL9	chemokine (C-X-C motif) ligand 9	0.042
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.039
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.038	Mouse
MICA	MHC class I polypeptide-related sequence A	0.033
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.031
CDCP1	CUB domain containing protein 1	0.031
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.028	Human
PDPK1	3-phosphoinositide dependent protein kinase-1	0.027
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.027
CD80	CD80 molecule	0.025
CXCL10	chemokine (C-X-C motif) ligand 10	0.025
BAD	BCL2-associated agonist of cell death	0.025
CCL14	chemokine (C-C motif) ligand 14	0.024	Human
HPCAL4	hippocalcin like 4	0.023
GNB2L1	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1	0.021
CXCL13	chemokine (C-X-C motif) ligand 13	0.021
NCF1	neutrophil cytosolic factor 1	0.021
ZNF71	zinc finger protein 71	0.021
SH3RF1	SH3 domain containing ring finger 1	0.021
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.020
CYBA	cytochrome b-245, alpha polypeptide	0.019
TMSB10	thymosin beta 10	0.018
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.018	Mouse
TRADD	TNFRSF1A-associated via death domain	0.017
VHL	von Hippel-Lindau tumor suppressor	0.017	Mouse
RNR2	l-rRNA	0.017
CA12	carbonic anhydrase XII	0.017
TP53BP2	tumor protein p53 binding protein, 2	0.016
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.016
WRN	Werner syndrome, RecQ helicase-like	0.014
TSC22D1	TSC22 domain family, member 1	0.014
ZHX1	zinc fingers and homeoboxes 1	0.014
CTBP2	C-terminal binding protein 2	0.014
HUWE1	HECT, UBA and WWE domain containing 1	0.014
VCAM1	vascular cell adhesion molecule 1	0.013
TRIM38	tripartite motif containing 38	0.013
CRLF3	cytokine receptor-like factor 3	0.013
CXCL11	chemokine (C-X-C motif) ligand 11	0.013
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.012	Human
IL2RG	interleukin 2 receptor, gamma	0.012
IL6	interleukin 6 (interferon, beta 2)	0.012
IL10	interleukin 10	0.012
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.012
IL8	interleukin 8	0.012
BCL10	B-cell CLL/lymphoma 10	0.011	Mouse
NUMB	numb homolog (Drosophila)	0.011
PRKCB	protein kinase C, beta	0.011
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.011
RNF144B	ring finger protein 144B	0.011
PML	promyelocytic leukemia	0.011
DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2	0.011
IL32	interleukin 32	0.011
SSX4	synovial sarcoma, X breakpoint 4	0.011
CCL22	chemokine (C-C motif) ligand 22	0.011
CD2	CD2 molecule	0.011
CCR1	chemokine (C-C motif) receptor 1	0.010
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.010
IFNG	interferon, gamma	0.010
CUL2	cullin 2	0.010