IMP: Integrative Multi-species Prediction

Homo sapiens

4 genes annotated in human

Multi-species View

positive regulation of t cell apoptotic process

GO:0070234

Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of t cell apoptotic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of t cell apoptotic process" (in gray)

Name	Description	Probability	Func Analog Organism
CCR5	chemokine (C-C motif) receptor 5	0.999
CCL5	chemokine (C-C motif) ligand 5	0.997
IL8	interleukin 8	0.995
CCL4	chemokine (C-C motif) ligand 4	0.982	Human
CXCL2	chemokine (C-X-C motif) ligand 2	0.972
CCL13	chemokine (C-C motif) ligand 13	0.965	Human
CXCL3	chemokine (C-X-C motif) ligand 3	0.943
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.926
IL6	interleukin 6 (interferon, beta 2)	0.889
CXCL9	chemokine (C-X-C motif) ligand 9	0.865
IL1B	interleukin 1, beta	0.831
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.828	Human
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.814
IDE	insulin-degrading enzyme	0.813
CCL2	chemokine (C-C motif) ligand 2	0.667	Human
CCL8	chemokine (C-C motif) ligand 8	0.390	Human
CD80	CD80 molecule	0.327
CXCL5	chemokine (C-X-C motif) ligand 5	0.295
CXCL10	chemokine (C-X-C motif) ligand 10	0.278
INHBA	inhibin, beta A	0.249
C1QA	complement component 1, q subcomponent, A chain	0.231
ICAM1	intercellular adhesion molecule 1	0.219
CCL3	chemokine (C-C motif) ligand 3	0.216	Human
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.203
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.193
SELE	selectin E	0.186
CD83	CD83 molecule	0.185
CXCL13	chemokine (C-X-C motif) ligand 13	0.173
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.156
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.156
CCL20	chemokine (C-C motif) ligand 20	0.146	Human
IL2RA	interleukin 2 receptor, alpha	0.144
CCR7	chemokine (C-C motif) receptor 7	0.133
TRAF1	TNF receptor-associated factor 1	0.130
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.130
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.124
DPP4	dipeptidyl-peptidase 4	0.115
TNF	tumor necrosis factor	0.114
CCL22	chemokine (C-C motif) ligand 22	0.114
IL1A	interleukin 1, alpha	0.106
IFNG	interferon, gamma	0.098
C1QC	complement component 1, q subcomponent, C chain	0.097
GNLY	granulysin	0.096
ARRB1	arrestin, beta 1	0.077
CCL7	chemokine (C-C motif) ligand 7	0.070	Human
CCR3	chemokine (C-C motif) receptor 3	0.069
RGS1	regulator of G-protein signaling 1	0.067
CMKLR1	chemokine-like receptor 1	0.067
VCAM1	vascular cell adhesion molecule 1	0.063
CH25H	cholesterol 25-hydroxylase	0.056
IL7R	interleukin 7 receptor	0.052
FPR3	formyl peptide receptor 3	0.049
DARC	Duffy blood group, chemokine receptor	0.049
CCL23	chemokine (C-C motif) ligand 23	0.042	Human
CCR1	chemokine (C-C motif) receptor 1	0.042
FZD1	frizzled homolog 1 (Drosophila)	0.042
BIRC3	baculoviral IAP repeat containing 3	0.040
CXCL11	chemokine (C-X-C motif) ligand 11	0.040
BCL2	B-cell CLL/lymphoma 2	0.038
SRGN	serglycin	0.037
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.036
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.036
ZC3H12A	zinc finger CCCH-type containing 12A	0.034
IL2RB	interleukin 2 receptor, beta	0.034
CD40	CD40 molecule, TNF receptor superfamily member 5	0.033
CCL3L3	chemokine (C-C motif) ligand 3-like 3	0.033
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.032
XCL2	chemokine (C motif) ligand 2	0.029
CCR4	chemokine (C-C motif) receptor 4	0.029
CD160	CD160 molecule	0.029
RGS16	regulator of G-protein signaling 16	0.028
SLAMF8	SLAM family member 8	0.027
UBD	ubiquitin D	0.027
CD209	CD209 molecule	0.026
IL10	interleukin 10	0.026
IL18RAP	interleukin 18 receptor accessory protein	0.026
STAT4	signal transducer and activator of transcription 4	0.026
SLCO2B1	solute carrier organic anion transporter family, member 2B1	0.025
HIPK2	homeodomain interacting protein kinase 2	0.024
ADAMDEC1	ADAM-like, decysin 1	0.024
OSMR	oncostatin M receptor	0.024
PLA2G2A	phospholipase A2, group IIA (platelets, synovial fluid)	0.022
IL32	interleukin 32	0.021
MSC	musculin	0.021
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.021
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.020
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.020
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.020
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.019
IL1R2	interleukin 1 receptor, type II	0.019
SLAMF7	SLAM family member 7	0.019
PI3	peptidase inhibitor 3, skin-derived	0.018
PDPN	podoplanin	0.018
SRA1	steroid receptor RNA activator 1	0.017
CCL19	chemokine (C-C motif) ligand 19	0.017	Human
CSF1	colony stimulating factor 1 (macrophage)	0.017
CCL21	chemokine (C-C motif) ligand 21	0.017
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.017
F3	coagulation factor III (thromboplastin, tissue factor)	0.016
THBS1	thrombospondin 1	0.016
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.016
BMP2	bone morphogenetic protein 2	0.016
H2AFX	H2A histone family, member X	0.016
RPS19BP1	ribosomal protein S19 binding protein 1	0.016
UNC119	unc-119 homolog (C. elegans)	0.015
IDO1	indoleamine 2,3-dioxygenase 1	0.015
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.015
CXCR6	chemokine (C-X-C motif) receptor 6	0.015
KLRB1	killer cell lectin-like receptor subfamily B, member 1	0.015
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.014
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.014
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.014
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.014	Mouse
C5AR1	complement component 5a receptor 1	0.014
RRAD	Ras-related associated with diabetes	0.014
SOD2	superoxide dismutase 2, mitochondrial	0.014
BCL2A1	BCL2-related protein A1	0.014
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.014
C2	complement component 2	0.014
AQP9	aquaporin 9	0.014
PTX3	pentraxin 3, long	0.014
IL18R1	interleukin 18 receptor 1	0.013
CCBP2	chemokine binding protein 2	0.013
SDS	serine dehydratase	0.013
WISP1	WNT1 inducible signaling pathway protein 1	0.013
ELK1	ELK1, member of ETS oncogene family	0.013
P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	0.013
SPP1	secreted phosphoprotein 1	0.013
G0S2	G0/G1switch 2	0.013
IL2RG	interleukin 2 receptor, gamma	0.012
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.012
PIAS4	protein inhibitor of activated STAT, 4	0.012
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.012
MKI67IP	MKI67 (FHA domain) interacting nucleolar phosphoprotein	0.012
CCRL2	chemokine (C-C motif) receptor-like 2	0.012
GPR109B	G protein-coupled receptor 109B	0.012
MCRS1	microspherule protein 1	0.012
CRMP1	collapsin response mediator protein 1	0.012
PLA2G7	phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)	0.012
DUSP2	dual specificity phosphatase 2	0.012
CINP	cyclin-dependent kinase 2 interacting protein	0.012
MOXD1	monooxygenase, DBH-like 1	0.011
NNMT	nicotinamide N-methyltransferase	0.011
SAA2	serum amyloid A2	0.011
APTX	aprataxin	0.011
IL21R	interleukin 21 receptor	0.011
XCL1	chemokine (C motif) ligand 1	0.011	Human
SLC2A5	solute carrier family 2 (facilitated glucose/fructose transporter), member 5	0.011
IL1RN	interleukin 1 receptor antagonist	0.011
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.011
MYST1	MYST histone acetyltransferase 1	0.011
BOLA2B	bolA homolog 2B (E. coli)	0.010
TFPI2	tissue factor pathway inhibitor 2	0.010
ABI3BP	ABI family, member 3 (NESH) binding protein	0.010