IMP: Integrative Multi-species Prediction

Homo sapiens

28 genes annotated in human

nucleus organization

A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.

Loading network...

In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network

Save Options

Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "nucleus organization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "nucleus organization" (in gray)

Name	Description	Probability	Func Analog Organism
KPNB1	karyopherin (importin) beta 1	0.996	Yeast
NUP107	nucleoporin 107kDa	0.995
NUP98	nucleoporin 98kDa	0.989
NXF1	nuclear RNA export factor 1	0.967
NUP153	nucleoporin 153kDa	0.952
AHCTF1	AT hook containing transcription factor 1	0.811
NUP160	nucleoporin 160kDa	0.753
NUP62	nucleoporin 62kDa	0.696
BCL9	B-cell CLL/lymphoma 9	0.587
SUN2	Sad1 and UNC84 domain containing 2	0.550
SYNE2	spectrin repeat containing, nuclear envelope 2	0.533	Human
KIF5B	kinesin family member 5B	0.491
SMN1	survival of motor neuron 1, telomeric	0.423
TMPO	thymopoietin	0.404	Zebrafish
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.393
NUP133	nucleoporin 133kDa	0.387
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	0.379
APC	adenomatous polyposis coli	0.346
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.336
NUP205	nucleoporin 205kDa	0.328
TACC3	transforming, acidic coiled-coil containing protein 3	0.300
SART3	squamous cell carcinoma antigen recognized by T cells 3	0.272
RANBP2	RAN binding protein 2	0.258	Worm
SYNE1	spectrin repeat containing, nuclear envelope 1	0.250
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.245
SSRP1	structure specific recognition protein 1	0.245
VCP	valosin containing protein	0.243
RFWD2	ring finger and WD repeat domain 2	0.243
MCM3	minichromosome maintenance complex component 3	0.234
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.177
CCT6A	chaperonin containing TCP1, subunit 6A (zeta 1)	0.165
POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	0.159
NUP50	nucleoporin 50kDa	0.157
TRIP12	thyroid hormone receptor interactor 12	0.141
SUN1	Sad1 and UNC84 domain containing 1	0.140
NUP93	nucleoporin 93kDa	0.139
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.138
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.132
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.126
PLK1	polo-like kinase 1	0.123	Worm Fly
BAZ1A	bromodomain adjacent to zinc finger domain, 1A	0.119
COIL	coilin	0.114	Zebrafish
HMGB1	high mobility group box 1	0.113
NUP43	nucleoporin 43kDa	0.110
WDR12	WD repeat domain 12	0.109
DAXX	death-domain associated protein	0.109	Rat
NUP85	nucleoporin 85kDa	0.108	Worm
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.100
LSM6	LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.099
SENP1	SUMO1/sentrin specific peptidase 1	0.099
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.099
TNPO1	transportin 1	0.096
GSPT1	G1 to S phase transition 1	0.094
AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)	0.094
DEK	DEK oncogene	0.094
IPO5	importin 5	0.088
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.088
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.085
RPS16	ribosomal protein S16	0.083
XPO1	exportin 1 (CRM1 homolog, yeast)	0.082
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.082
RANGAP1	Ran GTPase activating protein 1	0.082
WEE1	WEE1 homolog (S. pombe)	0.080
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.077
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.076	Worm
SEC31A	SEC31 homolog A (S. cerevisiae)	0.076
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.074
RPLP2	ribosomal protein, large, P2	0.074
CSNK1A1	casein kinase 1, alpha 1	0.073
TGS1	trimethylguanosine synthase 1	0.070
RPL18	ribosomal protein L18	0.066
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.065
RCC1	regulator of chromosome condensation 1	0.065
NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit	0.065
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.063	Fly
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.061
NUP37	nucleoporin 37kDa	0.060
NDEL1	nudE nuclear distribution gene E homolog (A. nidulans)-like 1	0.059
LMNB1	lamin B1	0.059	Worm Fly
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.058
RPL38	ribosomal protein L38	0.058
HEATR1	HEAT repeat containing 1	0.056
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.054
CBFB	core-binding factor, beta subunit	0.054
SMC3	structural maintenance of chromosomes 3	0.054
SNRPF	small nuclear ribonucleoprotein polypeptide F	0.051
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.050
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.049
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.049
ARID4B	AT rich interactive domain 4B (RBP1-like)	0.049
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.046
RAE1	RAE1 RNA export 1 homolog (S. pombe)	0.046	Yeast
DHX15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	0.046
MCM5	minichromosome maintenance complex component 5	0.043
NXT1	NTF2-like export factor 1	0.042
PNPT1	polyribonucleotide nucleotidyltransferase 1	0.041
CSE1L	CSE1 chromosome segregation 1-like (yeast)	0.041
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.039	Fly
LMNB2	lamin B2	0.039	Worm Fly
GTSE1	G-2 and S-phase expressed 1	0.038
SNW1	SNW domain containing 1	0.037
GLE1	GLE1 RNA export mediator homolog (yeast)	0.036
RBM25	RNA binding motif protein 25	0.036
PHAX	phosphorylated adaptor for RNA export	0.035
XPO5	exportin 5	0.035
TMEM188	transmembrane protein 188	0.035
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.034
RAB21	RAB21, member RAS oncogene family	0.034
RRM1	ribonucleotide reductase M1	0.033
CLIP1	CAP-GLY domain containing linker protein 1	0.033
SMARCAD1	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	0.033
ANP32E	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E	0.033
HNRNPUL1	heterogeneous nuclear ribonucleoprotein U-like 1	0.033
CLCN3	chloride channel 3	0.032
AMD1	adenosylmethionine decarboxylase 1	0.032
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.031
LARP4	La ribonucleoprotein domain family, member 4	0.031
RAB10	RAB10, member RAS oncogene family	0.031
LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.030
FBXO28	F-box protein 28	0.030
CENPF	centromere protein F, 350/400kDa (mitosin)	0.029
NAA50	N(alpha)-acetyltransferase 50, NatE catalytic subunit	0.029
API5	apoptosis inhibitor 5	0.029
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.029
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.028
CTPS	CTP synthase	0.028
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.028
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.028
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.027
POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.026
SRRT	serrate RNA effector molecule homolog (Arabidopsis)	0.026
CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	0.026
DBI	diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein)	0.026
PPP2R5E	protein phosphatase 2, regulatory subunit B', epsilon isoform	0.025
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.025
KARS	lysyl-tRNA synthetase	0.025
AGPS	alkylglycerone phosphate synthase	0.025
ERH	enhancer of rudimentary homolog (Drosophila)	0.024
RFWD3	ring finger and WD repeat domain 3	0.024
AR	androgen receptor	0.024
TNPO3	transportin 3	0.024
TIMELESS	timeless homolog (Drosophila)	0.024
GEMIN4	gem (nuclear organelle) associated protein 4	0.024
VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1	0.024
AXIN1	axin 1	0.023
GMPS	guanine monphosphate synthetase	0.023
PML	promyelocytic leukemia	0.023
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.023
TDP1	tyrosyl-DNA phosphodiesterase 1	0.022
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.022
XPO6	exportin 6	0.022
SNRPB	small nuclear ribonucleoprotein polypeptides B and B1	0.021
EMG1	EMG1 nucleolar protein homolog (S. cerevisiae)	0.021
TMEM33	transmembrane protein 33	0.021
PFDN2	prefoldin subunit 2	0.020
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.020
RPS11	ribosomal protein S11	0.020
STON2	stonin 2	0.020
CNOT7	CCR4-NOT transcription complex, subunit 7	0.020
SP100	SP100 nuclear antigen	0.019
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.019
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.019
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.019
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.019
CCT2	chaperonin containing TCP1, subunit 2 (beta)	0.019
GAPVD1	GTPase activating protein and VPS9 domains 1	0.019
TAF5	TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	0.019
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.019
RLF	rearranged L-myc fusion	0.019
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.019
STK3	serine/threonine kinase 3	0.019
JUN	jun proto-oncogene	0.019
FBXO30	F-box protein 30	0.019
POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)	0.018
GNL2	guanine nucleotide binding protein-like 2 (nucleolar)	0.018
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.018
TCOF1	Treacher Collins-Franceschetti syndrome 1	0.018
KLC4	kinesin light chain 4	0.018
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.018
ARMC1	armadillo repeat containing 1	0.017
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.017
NIPBL	Nipped-B homolog (Drosophila)	0.017
HDAC4	histone deacetylase 4	0.017
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.017
FXR1	fragile X mental retardation, autosomal homolog 1	0.017
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.017
RUNX1	runt-related transcription factor 1	0.017
SNRPD3	small nuclear ribonucleoprotein D3 polypeptide 18kDa	0.017
TPR	translocated promoter region (to activated MET oncogene)	0.017
ANKRD27	ankyrin repeat domain 27 (VPS9 domain)	0.017
RNGTT	RNA guanylyltransferase and 5'-phosphatase	0.016
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.016
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.016
XPO7	exportin 7	0.016
NUP188	nucleoporin 188kDa	0.016
POLR2B	polymerase (RNA) II (DNA directed) polypeptide B, 140kDa	0.016
C10orf18	chromosome 10 open reading frame 18	0.016
THOP1	thimet oligopeptidase 1	0.016
SACS	spastic ataxia of Charlevoix-Saguenay (sacsin)	0.016
RANBP1	RAN binding protein 1	0.016
ETF1	eukaryotic translation termination factor 1	0.016
RAN	RAN, member RAS oncogene family	0.016	Yeast
MCMBP	minichromosome maintenance complex binding protein	0.016
RAD21	RAD21 homolog (S. pombe)	0.015
USP10	ubiquitin specific peptidase 10	0.015
TWIST2	twist homolog 2 (Drosophila)	0.015
DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	0.015
C13orf34	chromosome 13 open reading frame 34	0.015
SNIP1	Smad nuclear interacting protein 1	0.015
LSM7	LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.015
E2F3	E2F transcription factor 3	0.015
MAK16	MAK16 homolog (S. cerevisiae)	0.015
VARS	valyl-tRNA synthetase	0.015
ANKRD17	ankyrin repeat domain 17	0.015
LMNA	lamin A/C	0.015	Mouse Worm Fly
CCNB2	cyclin B2	0.015
NLK	nemo-like kinase	0.014
TSC2	tuberous sclerosis 2	0.014
SEH1L	SEH1-like (S. cerevisiae)	0.014
HIST2H3C	histone cluster 2, H3c	0.014
RPS14	ribosomal protein S14	0.014
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.014
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.014
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.014	Worm
TRRAP	transformation/transcription domain-associated protein	0.014
BYSL	bystin-like	0.014
RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	0.014
KLHDC5	kelch domain containing 5	0.014
TMEM194A	transmembrane protein 194A	0.014
METAP1	methionyl aminopeptidase 1	0.014
MAPK7	mitogen-activated protein kinase 7	0.014
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.014
NUPL1	nucleoporin like 1	0.014
PRIM2	primase, DNA, polypeptide 2 (58kDa)	0.014	Worm
STRN3	striatin, calmodulin binding protein 3	0.014
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.014
WDYHV1	WDYHV motif containing 1	0.014
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.014
INTS8	integrator complex subunit 8	0.014
RBM15	RNA binding motif protein 15	0.014
IPO7	importin 7	0.014	Fly
LIG1	ligase I, DNA, ATP-dependent	0.013
CHERP	calcium homeostasis endoplasmic reticulum protein	0.013
DHX16	DEAH (Asp-Glu-Ala-His) box polypeptide 16	0.013
CHD1	chromodomain helicase DNA binding protein 1	0.013
MAP2K4	mitogen-activated protein kinase kinase 4	0.013
CKAP5	cytoskeleton associated protein 5	0.013	Fly
CCNB1	cyclin B1	0.013
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.013
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.013	Fly
ILF3	interleukin enhancer binding factor 3, 90kDa	0.013
HPRT1	hypoxanthine phosphoribosyltransferase 1	0.013
GSK3B	glycogen synthase kinase 3 beta	0.013
EPS15	epidermal growth factor receptor pathway substrate 15	0.012
PSME4	proteasome (prosome, macropain) activator subunit 4	0.012	Mouse
CTNNBL1	catenin, beta like 1	0.012
PUM1	pumilio homolog 1 (Drosophila)	0.012
POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)	0.012
ARRB2	arrestin, beta 2	0.012
NUP88	nucleoporin 88kDa	0.012
PPP6C	protein phosphatase 6, catalytic subunit	0.012
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.012
EIF2C3	eukaryotic translation initiation factor 2C, 3	0.012
MSH6	mutS homolog 6 (E. coli)	0.012
HSPB1	heat shock 27kDa protein 1	0.012
KATNA1	katanin p60 (ATPase containing) subunit A 1	0.012
SFPQ	splicing factor proline/glutamine-rich	0.012
TFCP2	transcription factor CP2	0.012
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.012
CEP76	centrosomal protein 76kDa	0.012
RPA1	replication protein A1, 70kDa	0.012
USP1	ubiquitin specific peptidase 1	0.011
PWP2	PWP2 periodic tryptophan protein homolog (yeast)	0.011
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.011
ZNF830	zinc finger protein 830	0.011
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.011
JRK	jerky homolog (mouse)	0.011
TRAIP	TRAF interacting protein	0.011
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.011
USPL1	ubiquitin specific peptidase like 1	0.011
LCLAT1	lysocardiolipin acyltransferase 1	0.011
PLAA	phospholipase A2-activating protein	0.011
SSSCA1	Sjogren syndrome/scleroderma autoantigen 1	0.011
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.011	Worm
MCM7	minichromosome maintenance complex component 7	0.011
C13orf23	chromosome 13 open reading frame 23	0.011
ERGIC2	ERGIC and golgi 2	0.011
ZW10	ZW10, kinetochore associated, homolog (Drosophila)	0.011
KIF22	kinesin family member 22	0.011
UCK2	uridine-cytidine kinase 2	0.011
TROAP	trophinin associated protein (tastin)	0.010
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.010
PREP	prolyl endopeptidase	0.010
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.010
SPATA5	spermatogenesis associated 5	0.010
MTF2	metal response element binding transcription factor 2	0.010
SUMO4	SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)	0.010
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.010
SKIV2L2	superkiller viralicidic activity 2-like 2 (S. cerevisiae)	0.010
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.010
TNRC6C	trinucleotide repeat containing 6C	0.010
BAIAP2	BAI1-associated protein 2	0.010
XPO4	exportin 4	0.010
GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa	0.010