IMP: Integrative Multi-species Prediction

Homo sapiens

9 genes annotated in human

regulation of protein homodimerization activity

Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of protein homodimerization activity"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of protein homodimerization activity" (in gray)

Name	Description	Probability	Func Analog Organism
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000
FHL2	four and a half LIM domains 2	0.999
TRAF2	TNF receptor-associated factor 2	0.946
PXN	paxillin	0.358
CD40	CD40 molecule, TNF receptor superfamily member 5	0.340
BCL2L1	BCL2-like 1	0.282	Human
FN1	fibronectin 1	0.278
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.257
TRAF3	TNF receptor-associated factor 3	0.246	Human
PDIA3	protein disulfide isomerase family A, member 3	0.220
PTPRC	protein tyrosine phosphatase, receptor type, C	0.197
ZNF420	zinc finger protein 420	0.176
ENG	endoglin	0.169
TRAF1	TNF receptor-associated factor 1	0.143	Human
BCL2	B-cell CLL/lymphoma 2	0.142
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.134	Human
TRADD	TNFRSF1A-associated via death domain	0.109
TICAM2	toll-like receptor adaptor molecule 2	0.097
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.095
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.091
SMAD1	SMAD family member 1	0.077
IRAK2	interleukin-1 receptor-associated kinase 2	0.067
BAD	BCL2-associated agonist of cell death	0.061
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.058
ZNF84	zinc finger protein 84	0.051
ZNF585A	zinc finger protein 585A	0.050
RIPK2	receptor-interacting serine-threonine kinase 2	0.044
CD63	CD63 molecule	0.042
ZNF432	zinc finger protein 432	0.041
ITGA6	integrin, alpha 6	0.037	Human
FHL3	four and a half LIM domains 3	0.032
ZNF260	zinc finger protein 260	0.029
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.027	Human
NUMBL	numb homolog (Drosophila)-like	0.026
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.024	Human
CD9	CD9 molecule	0.021
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.021
ZMYND11	zinc finger, MYND-type containing 11	0.019
ITGB4	integrin, beta 4	0.019
RNR2	l-rRNA	0.019
TRAF6	TNF receptor-associated factor 6	0.019	Human
ZNF623	zinc finger protein 623	0.018
MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	0.017
FLNA	filamin A, alpha	0.017
ARF6	ADP-ribosylation factor 6	0.016
ZNF140	zinc finger protein 140	0.016	Human
RNF144B	ring finger protein 144B	0.015
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.015
AR	androgen receptor	0.015
HDAC9	histone deacetylase 9	0.014
TRAF5	TNF receptor-associated factor 5	0.014	Human
SOD1	superoxide dismutase 1, soluble	0.014
BIRC3	baculoviral IAP repeat containing 3	0.013
TLR4	toll-like receptor 4	0.013
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.012	Human
ZNF12	zinc finger protein 12	0.012
ZNF512B	zinc finger protein 512B	0.012
HDAC4	histone deacetylase 4	0.011
ITGA7	integrin, alpha 7	0.011	Human
ZNF571	zinc finger protein 571	0.011
BIRC2	baculoviral IAP repeat containing 2	0.011
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.010