IMP: Integrative Multi-species Prediction

Homo sapiens

8 genes annotated in human

polyketide metabolic process

The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.

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In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "polyketide metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "polyketide metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	1.000
AKR7A2	aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase)	0.988
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	0.985
AKR7A3	aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)	0.981	Human
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.632
IL1R1	interleukin 1 receptor, type I	0.312
IL1RAP	interleukin 1 receptor accessory protein	0.060
ZHX1	zinc fingers and homeoboxes 1	0.027
HADH	hydroxyacyl-CoA dehydrogenase	0.021
IL8	interleukin 8	0.020
IL1RN	interleukin 1 receptor antagonist	0.018
IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	0.017
PRMT2	protein arginine methyltransferase 2	0.016
CCL20	chemokine (C-C motif) ligand 20	0.014
C21orf33	chromosome 21 open reading frame 33	0.013
PXMP2	peroxisomal membrane protein 2, 22kDa	0.012
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.010