IMP: Integrative Multi-species Prediction

Homo sapiens

119 genes annotated in human

extrinsic apoptotic signaling pathway

A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "extrinsic apoptotic signaling pathway"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "extrinsic apoptotic signaling pathway" (in gray)

Name	Description	Probability	Func Analog Organism
CASP8	caspase 8, apoptosis-related cysteine peptidase	1.000
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	1.000
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000
BCL2L1	BCL2-like 1	0.999	Human Mouse
TRAF2	TNF receptor-associated factor 2	0.998
BIRC3	baculoviral IAP repeat containing 3	0.998
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.998
CFLAR	CASP8 and FADD-like apoptosis regulator	0.997
BCL2	B-cell CLL/lymphoma 2	0.996
BIRC2	baculoviral IAP repeat containing 2	0.996
XIAP	X-linked inhibitor of apoptosis	0.995
TRAF1	TNF receptor-associated factor 1	0.995
TRAF3	TNF receptor-associated factor 3	0.994	Human
TRADD	TNFRSF1A-associated via death domain	0.993
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.991	Mouse
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.984	Human
FAS	Fas (TNF receptor superfamily, member 6)	0.983
FADD	Fas (TNFRSF6)-associated via death domain	0.983
FHL2	four and a half LIM domains 2	0.979
SMAD2	SMAD family member 2	0.972	Human
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.953	Human
BAX	BCL2-associated X protein	0.953
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.950
EGFR	epidermal growth factor receptor	0.947	Human
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.938	Human
RNF11	ring finger protein 11	0.932
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.930
RIPK2	receptor-interacting serine-threonine kinase 2	0.927	Human
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.914	Human Mouse
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.903	Human
STK4	serine/threonine kinase 4	0.890	Mouse
SMAD3	SMAD family member 3	0.885
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.880
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.877
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.871
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.870
AR	androgen receptor	0.869
UBC	ubiquitin C	0.850
TRAF5	TNF receptor-associated factor 5	0.840	Human
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.822
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.800
SQSTM1	sequestosome 1	0.799
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.796
PML	promyelocytic leukemia	0.793
TAL1	T-cell acute lymphocytic leukemia 1	0.786
FLNA	filamin A, alpha	0.783
BAD	BCL2-associated agonist of cell death	0.783
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.759
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.756
TNF	tumor necrosis factor	0.751
SMAD7	SMAD family member 7	0.751	Human
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.739	Human
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.734
TRAF6	TNF receptor-associated factor 6	0.726	Human
IL4R	interleukin 4 receptor	0.705
BID	BH3 interacting domain death agonist	0.700
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.696
TGFB1	transforming growth factor, beta 1	0.666
VEGFA	vascular endothelial growth factor A	0.665	Mouse
NRP1	neuropilin 1	0.661	Mouse
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.657	Human Mouse
BMP2	bone morphogenetic protein 2	0.654
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.639
ENG	endoglin	0.637
HCK	hemopoietic cell kinase	0.634	Human
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.630	Human
IL8	interleukin 8	0.608
SMAD4	SMAD family member 4	0.590	Human
CAV1	caveolin 1, caveolae protein, 22kDa	0.586
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.585
SMAD1	SMAD family member 1	0.584	Human
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.584
FGF1	fibroblast growth factor 1 (acidic)	0.573
MAPK1	mitogen-activated protein kinase 1	0.572
FGA	fibrinogen alpha chain	0.556
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.542
TANK	TRAF family member-associated NFKB activator	0.536
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.534
BTRC	beta-transducin repeat containing	0.532
TP53BP2	tumor protein p53 binding protein, 2	0.529
CXCL2	chemokine (C-X-C motif) ligand 2	0.517
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.504	Human
NLRC4	NLR family, CARD domain containing 4	0.502
SOCS3	suppressor of cytokine signaling 3	0.499
PLAU	plasminogen activator, urokinase	0.499
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.498
CD40	CD40 molecule, TNF receptor superfamily member 5	0.496	Human
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.495
TGFBR1	transforming growth factor, beta receptor 1	0.493
APP	amyloid beta (A4) precursor protein	0.483
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.452
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.449
PLAUR	plasminogen activator, urokinase receptor	0.445
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.444
FN1	fibronectin 1	0.442
GRB2	growth factor receptor-bound protein 2	0.441
ZMYND11	zinc finger, MYND-type containing 11	0.438
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.435
SKIL	SKI-like oncogene	0.422	Mouse
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.421
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.420	Human
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.420
FGFR1	fibroblast growth factor receptor 1	0.418	Human Mouse
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.412
FGB	fibrinogen beta chain	0.401
IRF1	interferon regulatory factor 1	0.400
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.396
OPTN	optineurin	0.396
PSEN1	presenilin 1	0.391
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.374
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.368
APC	adenomatous polyposis coli	0.354
APAF1	apoptotic peptidase activating factor 1	0.343
RNF31	ring finger protein 31	0.337
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.334	Human
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.332
STRN3	striatin, calmodulin binding protein 3	0.332
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.329
UBXN7	UBX domain protein 7	0.326
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.326
FGG	fibrinogen gamma chain	0.325
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.317
FKBP1A	FK506 binding protein 1A, 12kDa	0.313
AXIN1	axin 1	0.309
CCL20	chemokine (C-C motif) ligand 20	0.307
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.305
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.301
BCL2A1	BCL2-related protein A1	0.294	Human
ICAM1	intercellular adhesion molecule 1	0.287
IGF2R	insulin-like growth factor 2 receptor	0.281
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.280
DLG4	discs, large homolog 4 (Drosophila)	0.276
FYN	FYN oncogene related to SRC, FGR, YES	0.271	Human Rat
DAXX	death-domain associated protein	0.269
SPRR2A	small proline-rich protein 2A	0.267
IL6	interleukin 6 (interferon, beta 2)	0.262
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.259	Human
USP15	ubiquitin specific peptidase 15	0.258
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.257	Human
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.257
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.252
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.251
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.249	Human
ITGB5	integrin, beta 5	0.249
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.248
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.248
CXCL5	chemokine (C-X-C motif) ligand 5	0.243	Human
ANXA1	annexin A1	0.242
BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1	0.240
ITGB1BP3	integrin beta 1 binding protein 3	0.238
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.232	Human
SNAPIN	SNAP-associated protein	0.228
SIRT1	sirtuin 1	0.227
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.227
PLCG1	phospholipase C, gamma 1	0.226
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.225
IL1RN	interleukin 1 receptor antagonist	0.222	Human
MAPK14	mitogen-activated protein kinase 14	0.219
THBS1	thrombospondin 1	0.214
STK11	serine/threonine kinase 11	0.212
KRT8	keratin 8	0.212
SH3RF1	SH3 domain containing ring finger 1	0.212
IGF1R	insulin-like growth factor 1 receptor	0.211
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.211
KAT2B	K(lysine) acetyltransferase 2B	0.210
SPHK1	sphingosine kinase 1	0.208
TIMP3	TIMP metallopeptidase inhibitor 3	0.208
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.208
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.207	Human
STAT5A	signal transducer and activator of transcription 5A	0.206
SH3KBP1	SH3-domain kinase binding protein 1	0.204
VCAM1	vascular cell adhesion molecule 1	0.199
CD63	CD63 molecule	0.198
CALCOCO2	calcium binding and coiled-coil domain 2	0.194
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	0.194	Human
IRAK1	interleukin-1 receptor-associated kinase 1	0.191
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.190
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.189
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.189
CCL2	chemokine (C-C motif) ligand 2	0.188
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.185
SMAD5	SMAD family member 5	0.180	Human
SNAP23	synaptosomal-associated protein, 23kDa	0.179
SNX9	sorting nexin 9	0.178
UROD	uroporphyrinogen decarboxylase	0.176
RLN3	relaxin 3	0.175
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.174
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.173	Human
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.172
IQGAP1	IQ motif containing GTPase activating protein 1	0.171
BMPR1A	bone morphogenetic protein receptor, type IA	0.171	Human
SIAH1	seven in absentia homolog 1 (Drosophila)	0.168	Human
GCLC	glutamate-cysteine ligase, catalytic subunit	0.165	Mouse
DIABLO	diablo, IAP-binding mitochondrial protein	0.163
CASP2	caspase 2, apoptosis-related cysteine peptidase	0.163	Human Mouse
ACVR1	activin A receptor, type I	0.163
PXN	paxillin	0.161
IL1R1	interleukin 1 receptor, type I	0.159
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.159
FASLG	Fas ligand (TNF superfamily, member 6)	0.156
STK3	serine/threonine kinase 3	0.156	Mouse
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.155
SNAP25	synaptosomal-associated protein, 25kDa	0.155
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.149
SYK	spleen tyrosine kinase	0.148
WIPF1	WAS/WASL interacting protein family, member 1	0.147
PXMP2	peroxisomal membrane protein 2, 22kDa	0.147
PRKCA	protein kinase C, alpha	0.147
MUTED	muted homolog (mouse)	0.146
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.145
PLAT	plasminogen activator, tissue	0.144
GRB7	growth factor receptor-bound protein 7	0.144
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.143
SOD1	superoxide dismutase 1, soluble	0.141
SESN2	sestrin 2	0.141
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.140
MAP2K5	mitogen-activated protein kinase kinase 5	0.140	Rat
IRF7	interferon regulatory factor 7	0.140
ITGA6	integrin, alpha 6	0.140
ITGB1BP1	integrin beta 1 binding protein 1	0.139
FOXO1	forkhead box O1	0.138
TGFB3	transforming growth factor, beta 3	0.137
MAPK8	mitogen-activated protein kinase 8	0.136
ING2	inhibitor of growth family, member 2	0.135
BAK1	BCL2-antagonist/killer 1	0.133	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.132
CXCL10	chemokine (C-X-C motif) ligand 10	0.131	Human
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.129
TBK1	TANK-binding kinase 1	0.128
INHBA	inhibin, beta A	0.127
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.127	Human
BBC3	BCL2 binding component 3	0.126
YAP1	Yes-associated protein 1	0.125	Mouse
SP100	SP100 nuclear antigen	0.123
OAS2	2'-5'-oligoadenylate synthetase 2, 69/71kDa	0.123
SH3RF3	SH3 domain containing ring finger 3	0.120	Human
RASSF1	Ras association (RalGDS/AF-6) domain family member 1	0.120
SH2D1A	SH2 domain containing 1A	0.120
FAM101B	family with sequence similarity 101, member B	0.119
CCL5	chemokine (C-C motif) ligand 5	0.117
BIK	BCL2-interacting killer (apoptosis-inducing)	0.117
PF4	platelet factor 4	0.117
BCL3	B-cell CLL/lymphoma 3	0.117
IL1R2	interleukin 1 receptor, type II	0.115
LIMD1	LIM domains containing 1	0.115
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.115
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.114
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.114
STBD1	starch binding domain 1	0.113
SIAH2	seven in absentia homolog 2 (Drosophila)	0.113
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.112
RICTOR	RPTOR independent companion of MTOR, complex 2	0.111
WASL	Wiskott-Aldrich syndrome-like	0.110
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.107
CRYAB	crystallin, alpha B	0.107
MICA	MHC class I polypeptide-related sequence A	0.106
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.106
GCLM	glutamate-cysteine ligase, modifier subunit	0.106	Mouse
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.106
ITK	IL2-inducible T-cell kinase	0.106
RUNX1	runt-related transcription factor 1	0.106
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.103
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.102
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.102
FST	follistatin	0.102
MAPK7	mitogen-activated protein kinase 7	0.099
CARD11	caspase recruitment domain family, member 11	0.098
PPM1F	protein phosphatase, Mg2+/Mn2+ dependent, 1F	0.097
PIAS1	protein inhibitor of activated STAT, 1	0.096
EPHA2	EPH receptor A2	0.096
LAPTM4A	lysosomal protein transmembrane 4 alpha	0.093
IL7R	interleukin 7 receptor	0.093
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.093
ANXA2	annexin A2	0.093
PCNA	proliferating cell nuclear antigen	0.092
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.092
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.092
CCR2	chemokine (C-C motif) receptor 2	0.092
CCL4	chemokine (C-C motif) ligand 4	0.091
TLN1	talin 1	0.091
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.090
CYLD	cylindromatosis (turban tumor syndrome)	0.090
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.090
CXCL3	chemokine (C-X-C motif) ligand 3	0.089	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.089
TNC	tenascin C	0.088
CCL8	chemokine (C-C motif) ligand 8	0.088
TUBB6	tubulin, beta 6	0.088
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.087	Human
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.087
IRAK2	interleukin-1 receptor-associated kinase 2	0.087
OSMR	oncostatin M receptor	0.086
TP73	tumor protein p73	0.086
IL1A	interleukin 1, alpha	0.086	Human Mouse
HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	0.086
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.085	Mouse
ZFX	zinc finger protein, X-linked	0.084
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.084
ITGB4	integrin, beta 4	0.084
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.082
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.082
PDPK1	3-phosphoinositide dependent protein kinase-1	0.082
MAPK3	mitogen-activated protein kinase 3	0.081
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.081
JUP	junction plakoglobin	0.081
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.081
NCF2	neutrophil cytosolic factor 2	0.080
GDF5	growth differentiation factor 5	0.079
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.079
LDLR	low density lipoprotein receptor	0.079
FLNB	filamin B, beta	0.079
LRP1	low density lipoprotein receptor-related protein 1	0.079
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.079	Mouse
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.078
CCR7	chemokine (C-C motif) receptor 7	0.078
NRP2	neuropilin 2	0.078
RANGAP1	Ran GTPase activating protein 1	0.078
IFNGR1	interferon gamma receptor 1	0.078
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.078
PLEK	pleckstrin	0.077
PDK1	pyruvate dehydrogenase kinase, isozyme 1	0.077
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.077
PTEN	phosphatase and tensin homolog	0.077
TMSB10	thymosin beta 10	0.077
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.077
CSF1	colony stimulating factor 1 (macrophage)	0.076
CXCL11	chemokine (C-X-C motif) ligand 11	0.076	Human
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.076	Human
GAS7	growth arrest-specific 7	0.076
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.076
CSF3	colony stimulating factor 3 (granulocyte)	0.075
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.075
TNIP2	TNFAIP3 interacting protein 2	0.075
MYO6	myosin VI	0.075
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.074
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.074
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.074	Human
CRP	C-reactive protein, pentraxin-related	0.073
ZFYVE1	zinc finger, FYVE domain containing 1	0.073
SOCS1	suppressor of cytokine signaling 1	0.073
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.073
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.073
TBX5	T-box 5	0.073
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.073
CXCR3	chemokine (C-X-C motif) receptor 3	0.072
HDAC6	histone deacetylase 6	0.072
CA12	carbonic anhydrase XII	0.071
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.070
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.070
NRG1	neuregulin 1	0.070
ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	0.070
ZBTB16	zinc finger and BTB domain containing 16	0.069
SMAD6	SMAD family member 6	0.069	Human
SLC38A2	solute carrier family 38, member 2	0.069
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.069
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.068
PVR	poliovirus receptor	0.068
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.068
CCL7	chemokine (C-C motif) ligand 7	0.068
IRF4	interferon regulatory factor 4	0.068
GSK3B	glycogen synthase kinase 3 beta	0.068	Mouse
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.068
BAG1	BCL2-associated athanogene	0.067
NOTCH1	notch 1	0.067
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.067
RXRA	retinoid X receptor, alpha	0.067
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.067
IL1B	interleukin 1, beta	0.066
CTNND1	catenin (cadherin-associated protein), delta 1	0.065
MAPK6	mitogen-activated protein kinase 6	0.064
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.064
RASSF2	Ras association (RalGDS/AF-6) domain family member 2	0.064
S100A10	S100 calcium binding protein A10	0.064
ZC3HC1	zinc finger, C3HC-type containing 1	0.064
CSNK1A1	casein kinase 1, alpha 1	0.063
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.063
MEFV	Mediterranean fever	0.063
IGFBP5	insulin-like growth factor binding protein 5	0.063
IL2RG	interleukin 2 receptor, gamma	0.063
PDGFA	platelet-derived growth factor alpha polypeptide	0.063
RIOK3	RIO kinase 3 (yeast)	0.063
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.063
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.063
POLR2L	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	0.062
ZFYVE9	zinc finger, FYVE domain containing 9	0.062
LAMB3	laminin, beta 3	0.062
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.061
DLG3	discs, large homolog 3 (Drosophila)	0.061
CLU	clusterin	0.061
STC1	stanniocalcin 1	0.061
CHN2	chimerin (chimaerin) 2	0.061
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.061	Human
TRIM21	tripartite motif containing 21	0.061
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.061
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.060
ARHGAP5	Rho GTPase activating protein 5	0.060
HSPH1	heat shock 105kDa/110kDa protein 1	0.059
TUBA1A	tubulin, alpha 1a	0.059
USP9X	ubiquitin specific peptidase 9, X-linked	0.059
IL18RAP	interleukin 18 receptor accessory protein	0.059
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.059
FOSL1	FOS-like antigen 1	0.059
PDGFC	platelet derived growth factor C	0.058
FGF2	fibroblast growth factor 2 (basic)	0.058
NLRP3	NLR family, pyrin domain containing 3	0.058
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.058
TRAF4	TNF receptor-associated factor 4	0.058	Human
PHLDA2	pleckstrin homology-like domain, family A, member 2	0.058
TIFA	TRAF-interacting protein with forkhead-associated domain	0.058
ITSN1	intersectin 1 (SH3 domain protein)	0.057
IL10RA	interleukin 10 receptor, alpha	0.057
HIPK3	homeodomain interacting protein kinase 3	0.057	Human
PGF	placental growth factor	0.057
IL11	interleukin 11	0.056
PPBP	pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)	0.056	Human
RNF4	ring finger protein 4	0.056
LTB	lymphotoxin beta (TNF superfamily, member 3)	0.056
LGALS1	lectin, galactoside-binding, soluble, 1	0.056	Human
CD44	CD44 molecule (Indian blood group)	0.056
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.056	Human
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.056
TP53	tumor protein p53	0.056
SRI	sorcin	0.056
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.056
IER3	immediate early response 3	0.055
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.055
UPP1	uridine phosphorylase 1	0.055
BCL2L2	BCL2-like 2	0.055	Human
FHL3	four and a half LIM domains 3	0.055
ATF2	activating transcription factor 2	0.055
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.055
FGF7	fibroblast growth factor 7	0.054
GLIS2	GLIS family zinc finger 2	0.054
NGFR	nerve growth factor receptor	0.054
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.054
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.054
PARP1	poly (ADP-ribose) polymerase 1	0.054
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.054
IFNG	interferon, gamma	0.054
ITGB7	integrin, beta 7	0.053
PTK6	PTK6 protein tyrosine kinase 6	0.053	Human
KLF13	Kruppel-like factor 13	0.053
RIPK4	receptor-interacting serine-threonine kinase 4	0.052	Human
PRDX1	peroxiredoxin 1	0.052
CXCL9	chemokine (C-X-C motif) ligand 9	0.052	Human
IL2RB	interleukin 2 receptor, beta	0.052
PRKG1	protein kinase, cGMP-dependent, type I	0.052
TRO	trophinin	0.051
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.051
RIPK3	receptor-interacting serine-threonine kinase 3	0.051	Human
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.051
LAMC2	laminin, gamma 2	0.051
BANP	BTG3 associated nuclear protein	0.051
HBB	hemoglobin, beta	0.051
FGF10	fibroblast growth factor 10	0.051
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.051
VDAC1	voltage-dependent anion channel 1	0.051
TRAF3IP2	TRAF3 interacting protein 2	0.050
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.050
CASP8AP2	caspase 8 associated protein 2	0.050
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.050
HMGN2	high mobility group nucleosomal binding domain 2	0.050
RGS4	regulator of G-protein signaling 4	0.050
BLNK	B-cell linker	0.050
LCK	lymphocyte-specific protein tyrosine kinase	0.050	Human
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.050
TFPI2	tissue factor pathway inhibitor 2	0.050
HSPB1	heat shock 27kDa protein 1	0.049
BDNF	brain-derived neurotrophic factor	0.049	Human
KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	0.049
NCOA2	nuclear receptor coactivator 2	0.049
PI3	peptidase inhibitor 3, skin-derived	0.049
EFNA1	ephrin-A1	0.049
CCL22	chemokine (C-C motif) ligand 22	0.049
SORT1	sortilin 1	0.048
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.048
CDH5	cadherin 5, type 2 (vascular endothelium)	0.048
F2	coagulation factor II (thrombin)	0.048
DARC	Duffy blood group, chemokine receptor	0.047
VTN	vitronectin	0.047
PIAS2	protein inhibitor of activated STAT, 2	0.047
PTRF	polymerase I and transcript release factor	0.047
CD83	CD83 molecule	0.047
CCR1	chemokine (C-C motif) receptor 1	0.046
CD9	CD9 molecule	0.046
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.046
TIMP1	TIMP metallopeptidase inhibitor 1	0.045
KIAA1267	KIAA1267	0.045
PF4V1	platelet factor 4 variant 1	0.045	Human
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.045	Human
CTGF	connective tissue growth factor	0.045
DNAJC7	DnaJ (Hsp40) homolog, subfamily C, member 7	0.045
TSPO	translocator protein (18kDa)	0.045
ZHX1	zinc fingers and homeoboxes 1	0.045
VAV3	vav 3 guanine nucleotide exchange factor	0.045
PECAM1	platelet/endothelial cell adhesion molecule	0.044
IFITM1	interferon induced transmembrane protein 1 (9-27)	0.044
S100A6	S100 calcium binding protein A6	0.044
NPC2	Niemann-Pick disease, type C2	0.044
RARA	retinoic acid receptor, alpha	0.044
IRAK4	interleukin-1 receptor-associated kinase 4	0.044
SH2D2A	SH2 domain containing 2A	0.044
IL13	interleukin 13	0.044
MXD1	MAX dimerization protein 1	0.044
SELE	selectin E	0.044
SFRP1	secreted frizzled-related protein 1	0.044
AMBRA1	autophagy/beclin-1 regulator 1	0.044
JAK3	Janus kinase 3	0.043	Mouse
EREG	epiregulin	0.043
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.043
ACVRL1	activin A receptor type II-like 1	0.043	Human
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	0.043
AHNAK	AHNAK nucleoprotein	0.043
MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	0.043
ULK1	unc-51-like kinase 1 (C. elegans)	0.042
MAP2K3	mitogen-activated protein kinase kinase 3	0.042
COL6A1	collagen, type VI, alpha 1	0.042
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.042
WNT2	wingless-type MMTV integration site family member 2	0.042
DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60	0.042
MSC	musculin	0.041
HMHA1	histocompatibility (minor) HA-1	0.041
AZI2	5-azacytidine induced 2	0.041
MMP12	matrix metallopeptidase 12 (macrophage elastase)	0.041
FGFR3	fibroblast growth factor receptor 3	0.041
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.041
AXL	AXL receptor tyrosine kinase	0.041
FSTL1	follistatin-like 1	0.041
ORM1	orosomucoid 1	0.041
ZC3H12A	zinc finger CCCH-type containing 12A	0.041
CD48	CD48 molecule	0.041
MEF2A	myocyte enhancer factor 2A	0.041
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.041
THBD	thrombomodulin	0.041
CXCL12	chemokine (C-X-C motif) ligand 12	0.041
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.041	Human
MYD88	myeloid differentiation primary response gene (88)	0.040
CD80	CD80 molecule	0.040
DUSP9	dual specificity phosphatase 9	0.040
NTF3	neurotrophin 3	0.040	Human
AHR	aryl hydrocarbon receptor	0.040
HIST2H3C	histone cluster 2, H3c	0.040
PRNP	prion protein	0.040
LRRK2	leucine-rich repeat kinase 2	0.040
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.040
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.040	Human
LRP6	low density lipoprotein receptor-related protein 6	0.040
IL15RA	interleukin 15 receptor, alpha	0.040
TLR2	toll-like receptor 2	0.040
LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.039
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.039
LOXL2	lysyl oxidase-like 2	0.039
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.039
RUNX3	runt-related transcription factor 3	0.039	Mouse
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.039
PICALM	phosphatidylinositol binding clathrin assembly protein	0.039
CIB1	calcium and integrin binding 1 (calmyrin)	0.039
SORL1	sortilin-related receptor, L(DLR class) A repeats containing	0.039	Human
AQP9	aquaporin 9	0.039
EP300	E1A binding protein p300	0.039
LRP3	low density lipoprotein receptor-related protein 3	0.039
FZD7	frizzled homolog 7 (Drosophila)	0.039
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.039
CCL11	chemokine (C-C motif) ligand 11	0.039
TREM1	triggering receptor expressed on myeloid cells 1	0.039
DAPP1	dual adaptor of phosphotyrosine and 3-phosphoinositides	0.039
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.039
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.039
NCK1	NCK adaptor protein 1	0.038
SMG6	Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.038
TEK	TEK tyrosine kinase, endothelial	0.038
ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	0.038
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.038
TGIF1	TGFB-induced factor homeobox 1	0.038
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.038
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.038
RPTOR	regulatory associated protein of MTOR, complex 1	0.038
WDR26	WD repeat domain 26	0.038
STK17A	serine/threonine kinase 17a	0.038
HIC1	hypermethylated in cancer 1	0.037
INSR	insulin receptor	0.037
LIMK2	LIM domain kinase 2	0.037
CXCR6	chemokine (C-X-C motif) receptor 6	0.037
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.037
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.037
MAGEH1	melanoma antigen family H, 1	0.037
IGFBP1	insulin-like growth factor binding protein 1	0.037
DLG2	discs, large homolog 2 (Drosophila)	0.037
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.037
SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D	0.036
IGFBP3	insulin-like growth factor binding protein 3	0.036
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.036
JAG1	jagged 1	0.036
ANXA5	annexin A5	0.036
IDO1	indoleamine 2,3-dioxygenase 1	0.036
CCL19	chemokine (C-C motif) ligand 19	0.036
MEF2C	myocyte enhancer factor 2C	0.036
UBD	ubiquitin D	0.036
PSEN2	presenilin 2 (Alzheimer disease 4)	0.036	Mouse
FTL	ferritin, light polypeptide	0.036
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.036
IL2RA	interleukin 2 receptor, alpha	0.036
ATM	ataxia telangiectasia mutated	0.036
MAPK11	mitogen-activated protein kinase 11	0.036
GPR109B	G protein-coupled receptor 109B	0.036
F3	coagulation factor III (thromboplastin, tissue factor)	0.036
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.036
CTNNBIP1	catenin, beta interacting protein 1	0.036
PTHLH	parathyroid hormone-like hormone	0.036
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.036
NUMBL	numb homolog (Drosophila)-like	0.036
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.035
NOV	nephroblastoma overexpressed gene	0.035
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.035
TRIM8	tripartite motif containing 8	0.035
CD320	CD320 molecule	0.035
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.035
RARRES3	retinoic acid receptor responder (tazarotene induced) 3	0.035
SPTBN1	spectrin, beta, non-erythrocytic 1	0.035
MYST2	MYST histone acetyltransferase 2	0.035
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.035
VEGFC	vascular endothelial growth factor C	0.035
CD36	CD36 molecule (thrombospondin receptor)	0.035
TNIK	TRAF2 and NCK interacting kinase	0.035
ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6	0.035
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.035
MAP3K11	mitogen-activated protein kinase kinase kinase 11	0.035
FTH1	ferritin, heavy polypeptide 1	0.034
PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)	0.034
FGFR2	fibroblast growth factor receptor 2	0.034	Human
LAMP3	lysosomal-associated membrane protein 3	0.034
CCL1	chemokine (C-C motif) ligand 1	0.034
EMD	emerin	0.034
AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)	0.034
CSF1R	colony stimulating factor 1 receptor	0.034
STX5	syntaxin 5	0.034
IFITM3	interferon induced transmembrane protein 3 (1-8U)	0.034
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.034
SLAMF1	signaling lymphocytic activation molecule family member 1	0.034
TRIM33	tripartite motif containing 33	0.034
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.034
TGFB2	transforming growth factor, beta 2	0.034
S100A12	S100 calcium binding protein A12	0.034
CD7	CD7 molecule	0.034
CD163	CD163 molecule	0.034
POU2F2	POU class 2 homeobox 2	0.034
GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)	0.034
ANXA4	annexin A4	0.034
WDFY3	WD repeat and FYVE domain containing 3	0.033
IRF3	interferon regulatory factor 3	0.033
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.033
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.033
ADAM9	ADAM metallopeptidase domain 9	0.033
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.033
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.033	Human
NINJ1	ninjurin 1	0.033
CCL13	chemokine (C-C motif) ligand 13	0.033
F2R	coagulation factor II (thrombin) receptor	0.033
COL16A1	collagen, type XVI, alpha 1	0.033
CCR5	chemokine (C-C motif) receptor 5	0.033
RHEB	Ras homolog enriched in brain	0.033
GZMA	granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)	0.033
HBA2	hemoglobin, alpha 2	0.033
ACVR2B	activin A receptor, type IIB	0.033
CAV2	caveolin 2	0.033	Human
TRIP10	thyroid hormone receptor interactor 10	0.033
GDF15	growth differentiation factor 15	0.033
ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.033
EMP1	epithelial membrane protein 1	0.033
CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	0.033
ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.032
CD27	CD27 molecule	0.032
PTPRC	protein tyrosine phosphatase, receptor type, C	0.032	Mouse
TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	0.032
MEOX2	mesenchyme homeobox 2	0.032
ISG20	interferon stimulated exonuclease gene 20kDa	0.032
ZNF451	zinc finger protein 451	0.032
VIM	vimentin	0.032
S100A11	S100 calcium binding protein A11	0.032
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.032	Human
RGS14	regulator of G-protein signaling 14	0.032
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.032
CCPG1	cell cycle progression 1	0.032
BAG2	BCL2-associated athanogene 2	0.032
OLR1	oxidized low density lipoprotein (lectin-like) receptor 1	0.032
S100A3	S100 calcium binding protein A3	0.032
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	0.032
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.032
ASRGL1	asparaginase like 1	0.032
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.032
S100A4	S100 calcium binding protein A4	0.032
WBP5	WW domain binding protein 5	0.032
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.032	Mouse
SHANK2	SH3 and multiple ankyrin repeat domains 2	0.032
PTPRF	protein tyrosine phosphatase, receptor type, F	0.032
HUWE1	HECT, UBA and WWE domain containing 1	0.032
TNFSF9	tumor necrosis factor (ligand) superfamily, member 9	0.032
MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)	0.032
RIN1	Ras and Rab interactor 1	0.032
DST	dystonin	0.031
BLOC1S3	biogenesis of lysosomal organelles complex-1, subunit 3	0.031
CXCR2	chemokine (C-X-C motif) receptor 2	0.031
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.031
LRDD	leucine-rich repeats and death domain containing	0.031	Mouse
RPS4Y1	ribosomal protein S4, Y-linked 1	0.031
IFI44	interferon-induced protein 44	0.031
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.031
IL32	interleukin 32	0.031
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.031
BDKRB2	bradykinin receptor B2	0.031	Human
MAP2K1	mitogen-activated protein kinase kinase 1	0.031
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.031
DTX1	deltex homolog 1 (Drosophila)	0.031
EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	0.031
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.031
FCHO2	FCH domain only 2	0.031
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.031
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.030
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.030
IRF8	interferon regulatory factor 8	0.030
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.030
ATG2A	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.030
CHGB	chromogranin B (secretogranin 1)	0.030
SFRP2	secreted frizzled-related protein 2	0.030	Human Mouse
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	0.030
MTMR4	myotubularin related protein 4	0.030
ATXN3	ataxin 3	0.030
SH3BP5	SH3-domain binding protein 5 (BTK-associated)	0.030
CALR	calreticulin	0.030
SPP1	secreted phosphoprotein 1	0.029
SH2B3	SH2B adaptor protein 3	0.029
KYNU	kynureninase	0.029
C4orf14	chromosome 4 open reading frame 14	0.029
IFIH1	interferon induced with helicase C domain 1	0.029
CDK6	cyclin-dependent kinase 6	0.029
IGSF6	immunoglobulin superfamily, member 6	0.029
PDIA3	protein disulfide isomerase family A, member 3	0.029	Mouse
GREM1	gremlin 1	0.029
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.029
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.029	Human
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.029
CCND1	cyclin D1	0.029
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.029
SOCS5	suppressor of cytokine signaling 5	0.029
RFC1	replication factor C (activator 1) 1, 145kDa	0.029
DHH	desert hedgehog	0.029
SFRP4	secreted frizzled-related protein 4	0.029
SELL	selectin L	0.029
PRDX4	peroxiredoxin 4	0.029
DOK2	docking protein 2, 56kDa	0.029