IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

Multi-species View

regulation of astrocyte differentiation

GO:0048710

Any process that modulates the frequency, rate or extent of astrocyte differentiation.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of astrocyte differentiation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of astrocyte differentiation" (in gray)

Name	Description	Probability	Func Analog Organism
PLAU	plasminogen activator, urokinase	0.961
RIN3	Ras and Rab interactor 3	0.955
JAG1	jagged 1	0.904
DNM1	dynamin 1	0.785
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.724
BMPR1A	bone morphogenetic protein receptor, type IA	0.629
PLAUR	plasminogen activator, urokinase receptor	0.556
IL1R1	interleukin 1 receptor, type I	0.513
ALB	albumin	0.509
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.501
NOTCH3	notch 3	0.492
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.427
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.411
PLAT	plasminogen activator, tissue	0.334
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.275
SYNJ1	synaptojanin 1	0.254
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.219
FGF1	fibroblast growth factor 1 (acidic)	0.217
IFNGR1	interferon gamma receptor 1	0.184
BMP7	bone morphogenetic protein 7	0.176
BCAS2	breast carcinoma amplified sequence 2	0.170
SF3A1	splicing factor 3a, subunit 1, 120kDa	0.168
SNX9	sorting nexin 9	0.166
HIST1H3B	histone cluster 1, H3b	0.160
MAX	MYC associated factor X	0.156
MAML1	mastermind-like 1 (Drosophila)	0.155
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.153
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.145
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.145
SF3A2	splicing factor 3a, subunit 2, 66kDa	0.132
IL8	interleukin 8	0.132
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.124	Mouse
PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	0.110
PRPF6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae)	0.088
IL6R	interleukin 6 receptor	0.083
IL6	interleukin 6 (interferon, beta 2)	0.082
JAK1	Janus kinase 1	0.081
RBM10	RNA binding motif protein 10	0.079
JAK2	Janus kinase 2	0.078
SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)	0.078
FOSL1	FOS-like antigen 1	0.073
OSMR	oncostatin M receptor	0.072
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.071
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.069
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.068
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.068
LIFR	leukemia inhibitory factor receptor alpha	0.066
IL1RN	interleukin 1 receptor antagonist	0.066
JAG2	jagged 2	0.062
ITSN1	intersectin 1 (SH3 domain protein)	0.060
BMP2	bone morphogenetic protein 2	0.060	Mouse
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.059
FGA	fibrinogen alpha chain	0.058
PRCC	papillary renal cell carcinoma (translocation-associated)	0.057
EGR1	early growth response 1	0.057
FGFR2	fibroblast growth factor receptor 2	0.057
RNPS1	RNA binding protein S1, serine-rich domain	0.057
ICAM1	intercellular adhesion molecule 1	0.053
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.052	Mouse
CCL20	chemokine (C-C motif) ligand 20	0.052
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.051
FSTL1	follistatin-like 1	0.049
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.047
SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)	0.045
TAL1	T-cell acute lymphocytic leukemia 1	0.044
NOG	noggin	0.044	Mouse
DLL1	delta-like 1 (Drosophila)	0.042
NOTCH2	notch 2	0.041
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.041	Human
OLIG2	oligodendrocyte lineage transcription factor 2	0.040
SPHK1	sphingosine kinase 1	0.039
CXCL2	chemokine (C-X-C motif) ligand 2	0.039
CYR61	cysteine-rich, angiogenic inducer, 61	0.039
IGF1R	insulin-like growth factor 1 receptor	0.036
ZC3H12A	zinc finger CCCH-type containing 12A	0.035
CDK6	cyclin-dependent kinase 6	0.034
SUGP1	SURP and G patch domain containing 1	0.034
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.033
IER3	immediate early response 3	0.033
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.032
CCL2	chemokine (C-C motif) ligand 2	0.032
SOCS3	suppressor of cytokine signaling 3	0.031
SH3GL2	SH3-domain GRB2-like 2	0.031
SF3B3	splicing factor 3b, subunit 3, 130kDa	0.030
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.030
F3	coagulation factor III (thromboplastin, tissue factor)	0.029
SMAD7	SMAD family member 7	0.029
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.029
BCL2A1	BCL2-related protein A1	0.028
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.028
SF3B4	splicing factor 3b, subunit 4, 49kDa	0.028
HIST1H4F	histone cluster 1, H4f	0.027
KRT8	keratin 8	0.027
SART1	squamous cell carcinoma antigen recognized by T cells	0.026
GPKOW	G patch domain and KOW motifs	0.026
INHBA	inhibin, beta A	0.026
RUNX1	runt-related transcription factor 1	0.025
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	0.025
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.025
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.024
TNC	tenascin C	0.024
TOE1	target of EGR1, member 1 (nuclear)	0.024
APCS	amyloid P component, serum	0.023
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.023
FGFR1	fibroblast growth factor receptor 1	0.023
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.023
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.023
MYO1E	myosin IE	0.022
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.022
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.022	Mouse
CTGF	connective tissue growth factor	0.021
FGF18	fibroblast growth factor 18	0.021
SLC38A3	solute carrier family 38, member 3	0.021
EPHA2	EPH receptor A2	0.021
EPOR	erythropoietin receptor	0.021
CSNK1E	casein kinase 1, epsilon	0.021
HBEGF	heparin-binding EGF-like growth factor	0.021
RBM5	RNA binding motif protein 5	0.021
PTAFR	platelet-activating factor receptor	0.020
XIAP	X-linked inhibitor of apoptosis	0.020
SYN2	synapsin II	0.020
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.020
LTK	leukocyte receptor tyrosine kinase	0.020
SOX11	SRY (sex determining region Y)-box 11	0.020
CIR1	corepressor interacting with RBPJ, 1	0.020
CNTF	ciliary neurotrophic factor	0.020
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.020
PRKCG	protein kinase C, gamma	0.019
F10	coagulation factor X	0.019	Human
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.019
SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	0.018
NCAN	neurocan	0.018
MCC	mutated in colorectal cancers	0.018
SF3A3	splicing factor 3a, subunit 3, 60kDa	0.018
GFI1B	growth factor independent 1B transcription repressor	0.018
PLRG1	pleiotropic regulator 1 (PRL1 homolog, Arabidopsis)	0.017
SDC4	syndecan 4	0.017
LAS1L	LAS1-like (S. cerevisiae)	0.017
PLG	plasminogen	0.017
NHP2L1	NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)	0.017
EFNA1	ephrin-A1	0.017
CUX1	cut-like homeobox 1	0.017
SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2	0.017
PTHLH	parathyroid hormone-like hormone	0.017
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.017
THBS1	thrombospondin 1	0.017
EMP1	epithelial membrane protein 1	0.017
FAM110A	family with sequence similarity 110, member A	0.017
PIM1	pim-1 oncogene	0.017
SOX2	SRY (sex determining region Y)-box 2	0.017
BMPR1B	bone morphogenetic protein receptor, type IB	0.017
ANGPTL4	angiopoietin-like 4	0.016
SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1	0.016
UGCG	UDP-glucose ceramide glucosyltransferase	0.016
CAMKV	CaM kinase-like vesicle-associated	0.016
IL7R	interleukin 7 receptor	0.016
DHX38	DEAH (Asp-Glu-Ala-His) box polypeptide 38	0.016
EFNB2	ephrin-B2	0.016
FGB	fibrinogen beta chain	0.016
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.016
KAT2B	K(lysine) acetyltransferase 2B	0.016
GHR	growth hormone receptor	0.016
ATXN1L	ataxin 1-like	0.016
F7	coagulation factor VII (serum prothrombin conversion accelerator)	0.015	Human
GEM	GTP binding protein overexpressed in skeletal muscle	0.015
FHL1	four and a half LIM domains 1	0.015
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.015
TMEM47	transmembrane protein 47	0.015
LAMC2	laminin, gamma 2	0.015
SEPT4	septin 4	0.015
BCL3	B-cell CLL/lymphoma 3	0.015
PER1	period homolog 1 (Drosophila)	0.015
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.015
LRP2	low density lipoprotein receptor-related protein 2	0.015
CLCF1	cardiotrophin-like cytokine factor 1	0.015
ITIH3	inter-alpha (globulin) inhibitor H3	0.014
DLL3	delta-like 3 (Drosophila)	0.014	Rat
VTN	vitronectin	0.014
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.014
NGFR	nerve growth factor receptor	0.014
WNT11	wingless-type MMTV integration site family, member 11	0.014
REPS2	RALBP1 associated Eps domain containing 2	0.014
POU3F2	POU class 3 homeobox 2	0.014
HUWE1	HECT, UBA and WWE domain containing 1	0.014
CADM4	cell adhesion molecule 4	0.014
SMAD6	SMAD family member 6	0.014
ABO	ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)	0.014
GFAP	glial fibrillary acidic protein	0.014
BMP4	bone morphogenetic protein 4	0.014
LPHN3	latrophilin 3	0.014
IL1A	interleukin 1, alpha	0.014
STAT2	signal transducer and activator of transcription 2, 113kDa	0.014
EDN1	endothelin 1	0.014
SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.014
GPRC5A	G protein-coupled receptor, family C, group 5, member A	0.014
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.014
CHD4	chromodomain helicase DNA binding protein 4	0.014
EP300	E1A binding protein p300	0.014
RYR3	ryanodine receptor 3	0.014
TM4SF1	transmembrane 4 L six family member 1	0.014
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.014
PPL	periplakin	0.014
MYOD1	myogenic differentiation 1	0.014
CTNNBL1	catenin, beta like 1	0.014
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.014
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.014
TFPI2	tissue factor pathway inhibitor 2	0.013
LAMB3	laminin, beta 3	0.013
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.013
COL2A1	collagen, type II, alpha 1	0.013
ZBTB17	zinc finger and BTB domain containing 17	0.013
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.013
GRB7	growth factor receptor-bound protein 7	0.013
SARDH	sarcosine dehydrogenase	0.013
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.013
GRB2	growth factor receptor-bound protein 2	0.013
STC1	stanniocalcin 1	0.013
SNAI1	snail homolog 1 (Drosophila)	0.013
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.013
FBXW8	F-box and WD repeat domain containing 8	0.013
GAB1	GRB2-associated binding protein 1	0.013
TNIP1	TNFAIP3 interacting protein 1	0.013
PPAP2B	phosphatidic acid phosphatase type 2B	0.013
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.013
PMEPA1	prostate transmembrane protein, androgen induced 1	0.013
FRS2	fibroblast growth factor receptor substrate 2	0.013
PTBP1	polypyrimidine tract binding protein 1	0.013
EGFL7	EGF-like-domain, multiple 7	0.013
C1QL1	complement component 1, q subcomponent-like 1	0.013
INSR	insulin receptor	0.013
ACD	adrenocortical dysplasia homolog (mouse)	0.013
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.013
PTPRD	protein tyrosine phosphatase, receptor type, D	0.013
RGS16	regulator of G-protein signaling 16	0.013
GAL3ST1	galactose-3-O-sulfotransferase 1	0.013
KNG1	kininogen 1	0.013
SOX9	SRY (sex determining region Y)-box 9	0.013
EGR3	early growth response 3	0.013
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.013
MAN1A1	mannosidase, alpha, class 1A, member 1	0.013
FAM110C	family with sequence similarity 110, member C	0.013
SNTG2	syntrophin, gamma 2	0.013
CRP	C-reactive protein, pentraxin-related	0.013
NTSR2	neurotensin receptor 2	0.013
FGG	fibrinogen gamma chain	0.012
C19orf43	chromosome 19 open reading frame 43	0.012
FST	follistatin	0.012
HRH1	histamine receptor H1	0.012
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.012
HMGA2	high mobility group AT-hook 2	0.012
UNC5C	unc-5 homolog C (C. elegans)	0.012
PVR	poliovirus receptor	0.012
SOX10	SRY (sex determining region Y)-box 10	0.012
CHST11	carbohydrate (chondroitin 4) sulfotransferase 11	0.012
NHLH1	nescient helix loop helix 1	0.012
IRS2	insulin receptor substrate 2	0.012
TAOK1	TAO kinase 1	0.012
IRS1	insulin receptor substrate 1	0.012
JMJD6	jumonji domain containing 6	0.012
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.012
AHSG	alpha-2-HS-glycoprotein	0.012
RNF130	ring finger protein 130	0.012
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.012
IL13RA1	interleukin 13 receptor, alpha 1	0.012
SERPINB8	serpin peptidase inhibitor, clade B (ovalbumin), member 8	0.012
TBCD	tubulin folding cofactor D	0.012
RPL11	ribosomal protein L11	0.012
INHBB	inhibin, beta B	0.012
NDP	Norrie disease (pseudoglioma)	0.012
DUSP5	dual specificity phosphatase 5	0.012
CHGB	chromogranin B (secretogranin 1)	0.012
EPHA3	EPH receptor A3	0.012
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.012
FGF9	fibroblast growth factor 9 (glia-activating factor)	0.012
AMOTL2	angiomotin like 2	0.012
HES5	hairy and enhancer of split 5 (Drosophila)	0.012	Mouse
NRCAM	neuronal cell adhesion molecule	0.012
CXCL3	chemokine (C-X-C motif) ligand 3	0.012
IGFBP1	insulin-like growth factor binding protein 1	0.012
TGFB2	transforming growth factor, beta 2	0.011
ASGR2	asialoglycoprotein receptor 2	0.011
FGFR4	fibroblast growth factor receptor 4	0.011
DUSP9	dual specificity phosphatase 9	0.011
DMWD	dystrophia myotonica, WD repeat containing	0.011
PROC	protein C (inactivator of coagulation factors Va and VIIIa)	0.011	Human
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.011
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.011
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.011
TREM1	triggering receptor expressed on myeloid cells 1	0.011
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.011
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.011
CRHBP	corticotropin releasing hormone binding protein	0.011
CD83	CD83 molecule	0.011
RELN	reelin	0.011
BHLHE40	basic helix-loop-helix family, member e40	0.011
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	0.011
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.011
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.011
ADD2	adducin 2 (beta)	0.011
TPST1	tyrosylprotein sulfotransferase 1	0.011
PIPOX	pipecolic acid oxidase	0.011
TCF4	transcription factor 4	0.011
SFRP5	secreted frizzled-related protein 5	0.011
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.011
PDLIM4	PDZ and LIM domain 4	0.011
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.011
TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.011
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.011
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.011
TTYH1	tweety homolog 1 (Drosophila)	0.011
GLI1	GLI family zinc finger 1	0.011
SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2	0.011
GAP43	growth associated protein 43	0.011
EREG	epiregulin	0.011
BAI1	brain-specific angiogenesis inhibitor 1	0.011
APOA2	apolipoprotein A-II	0.011
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.011
MAG	myelin associated glycoprotein	0.011
CELF3	CUGBP, Elav-like family member 3	0.011
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.011
IER2	immediate early response 2	0.011
GATA2	GATA binding protein 2	0.011
UNC13A	unc-13 homolog A (C. elegans)	0.011
CCL7	chemokine (C-C motif) ligand 7	0.011
CCDC17	coiled-coil domain containing 17	0.010
PLK3	polo-like kinase 3	0.010
CPD	carboxypeptidase D	0.010
EXOC7	exocyst complex component 7	0.010
PTX3	pentraxin 3, long	0.010
SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	0.010
KRT18	keratin 18	0.010
DNM3	dynamin 3	0.010
FGL1	fibrinogen-like 1	0.010
MEF2A	myocyte enhancer factor 2A	0.010
SH3BP4	SH3-domain binding protein 4	0.010
CSF1	colony stimulating factor 1 (macrophage)	0.010
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.010
IL11	interleukin 11	0.010
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.010
MSI1	musashi homolog 1 (Drosophila)	0.010
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.010
CTTN	cortactin	0.010
DPF1	D4, zinc and double PHD fingers family 1	0.010
F11	coagulation factor XI	0.010
CXCL5	chemokine (C-X-C motif) ligand 5	0.010
ITIH4	inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)	0.010
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.010
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.010
IL13RA2	interleukin 13 receptor, alpha 2	0.010
CXCR2	chemokine (C-X-C motif) receptor 2	0.010
NKX2-2	NK2 homeobox 2	0.010
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.010
ARL4C	ADP-ribosylation factor-like 4C	0.010
EMX2	empty spiracles homeobox 2	0.010
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.010
MASP2	mannan-binding lectin serine peptidase 2	0.010
NLRP3	NLR family, pyrin domain containing 3	0.010
ITIH1	inter-alpha (globulin) inhibitor H1	0.010
NGF	nerve growth factor (beta polypeptide)	0.010
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.010
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.010
G0S2	G0/G1switch 2	0.010
ACTN1	actinin, alpha 1	0.010
ASTN1	astrotactin 1	0.010
RASL10A	RAS-like, family 10, member A	0.010
FBP1	fructose-1,6-bisphosphatase 1	0.010
SEZ6L	seizure related 6 homolog (mouse)-like	0.010
F5	coagulation factor V (proaccelerin, labile factor)	0.010
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.010
HOXD9	homeobox D9	0.010