IMP: Integrative Multi-species Prediction

Homo sapiens

1 genes annotated in human

Multi-species View

asymmetric stem cell division

GO:0098722

Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "asymmetric stem cell division"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "asymmetric stem cell division" (in gray)

Name	Description	Probability	Func Analog Organism
STK11	serine/threonine kinase 11	1.000	Worm Fly
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	1.000	Fly
PRKCZ	protein kinase C, zeta	1.000
CCT8	chaperonin containing TCP1, subunit 8 (theta)	1.000
INSR	insulin receptor	1.000	Fly
PARD6G	par-6 partitioning defective 6 homolog gamma (C. elegans)	0.998	Fly
CDK2	cyclin-dependent kinase 2	0.997
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.996	Fly
GRB10	growth factor receptor-bound protein 10	0.994
IRS1	insulin receptor substrate 1	0.992	Fly
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.989	Fly
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.985
PARD6A	par-6 partitioning defective 6 homolog alpha (C. elegans)	0.983	Fly
STRADA	STE20-related kinase adaptor alpha	0.981	Worm
MAPT	microtubule-associated protein tau	0.969
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.953	Fly
PKP2	plakophilin 2	0.951
JUB	jub, ajuba homolog (Xenopus laevis)	0.947
PRKCI	protein kinase C, iota	0.918
IGF1R	insulin-like growth factor 1 receptor	0.886	Fly
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.884	Fly
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.880
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.871
EGFR	epidermal growth factor receptor	0.852
PPP4C	protein phosphatase 4, catalytic subunit	0.821
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.818	Fly
IRS2	insulin receptor substrate 2	0.782	Fly
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.765
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.764
PLCG1	phospholipase C, gamma 1	0.752
ZBED1	zinc finger, BED-type containing 1	0.709
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.700
SKP2	S-phase kinase-associated protein 2 (p45)	0.645
TP53	tumor protein p53	0.566
TCP1	t-complex 1	0.550
PCNA	proliferating cell nuclear antigen	0.542
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.505
SKA3	spindle and kinetochore associated complex subunit 3	0.494
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.441	Fly
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.436
CAB39	calcium binding protein 39	0.433	Worm
CCNB1	cyclin B1	0.432
CCNE1	cyclin E1	0.427
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.414
CDK1	cyclin-dependent kinase 1	0.412	Fly
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.395
SFN	stratifin	0.388
TNIP2	TNFAIP3 interacting protein 2	0.379
STRADB	STE20-related kinase adaptor beta	0.366	Worm
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.350
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.331
KIF23	kinesin family member 23	0.319
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.306	Fly
NUMA1	nuclear mitotic apparatus protein 1	0.306
OXSR1	oxidative-stress responsive 1	0.294
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.286
NGF	nerve growth factor (beta polypeptide)	0.261
NCF2	neutrophil cytosolic factor 2	0.256
F11R	F11 receptor	0.236
LLGL2	lethal giant larvae homolog 2 (Drosophila)	0.228	Fly
LAT	linker for activation of T cells	0.217
MARK2	MAP/microtubule affinity-regulating kinase 2	0.211	Worm
SH2B1	SH2B adaptor protein 1	0.204
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.200	Fly
RHOA	ras homolog gene family, member A	0.190
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.189	Fly
CENPJ	centromere protein J	0.189
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.180
NTF4	neurotrophin 4	0.179
DOCK7	dedicator of cytokinesis 7	0.176
GNG2	guanine nucleotide binding protein (G protein), gamma 2	0.162
BCAR1	breast cancer anti-estrogen resistance 1	0.160
STAT5B	signal transducer and activator of transcription 5B	0.156
LNX1	ligand of numb-protein X 1	0.153
GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3	0.152	Fly
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.150
GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1	0.148	Fly
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.147
MARK4	MAP/microtubule affinity-regulating kinase 4	0.136	Worm
CCDC158	coiled-coil domain containing 158	0.136
RFWD2	ring finger and WD repeat domain 2	0.136
JAK2	Janus kinase 2	0.132
PLCB3	phospholipase C, beta 3 (phosphatidylinositol-specific)	0.127
CAV1	caveolin 1, caveolae protein, 22kDa	0.123
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.120
CCND2	cyclin D2	0.113
MKRN1	makorin ring finger protein 1	0.112
CCND1	cyclin D1	0.110
CCNB2	cyclin B2	0.107
KIAA0101	KIAA0101	0.107
GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.105	Fly
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.104
PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	0.104
LOXL4	lysyl oxidase-like 4	0.102
DCTN1	dynactin 1	0.101
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.100
NMT2	N-myristoyltransferase 2	0.100
SASS6	spindle assembly 6 homolog (C. elegans)	0.099
STK39	serine threonine kinase 39	0.098
TRIP12	thyroid hormone receptor interactor 12	0.098
FYN	FYN oncogene related to SRC, FGR, YES	0.096
CDH5	cadherin 5, type 2 (vascular endothelium)	0.093
ZNF71	zinc finger protein 71	0.090
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.089
TRAF5	TNF receptor-associated factor 5	0.085
SERTAD4	SERTA domain containing 4	0.084
ERRFI1	ERBB receptor feedback inhibitor 1	0.083
TNS4	tensin 4	0.081
EGR1	early growth response 1	0.079
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.078
KLC1	kinesin light chain 1	0.077
CCND3	cyclin D3	0.077
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.077
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.076
GCSH	glycine cleavage system protein H (aminomethyl carrier)	0.075
ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1	0.075
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.075
HOXD8	homeobox D8	0.072
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.072
PPME1	protein phosphatase methylesterase 1	0.071
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.071
GHR	growth hormone receptor	0.068
PPP2R2D	protein phosphatase 2, regulatory subunit B, delta	0.068	Fly
JAM3	junctional adhesion molecule 3	0.066
GNG5	guanine nucleotide binding protein (G protein), gamma 5	0.065	Fly
PKP3	plakophilin 3	0.065
KIAA0802	KIAA0802	0.064
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	0.063
JAM2	junctional adhesion molecule 2	0.063
CSNK1D	casein kinase 1, delta	0.062
EPOR	erythropoietin receptor	0.062
CRLF3	cytokine receptor-like factor 3	0.061
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.060
PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	0.059
SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	0.058
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.058
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.057
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.057
VHL	von Hippel-Lindau tumor suppressor	0.056
TP53BP2	tumor protein p53 binding protein, 2	0.054
CYB5R4	cytochrome b5 reductase 4	0.054
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.053
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.053
PRKCA	protein kinase C, alpha	0.052
GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.052
GAB1	GRB2-associated binding protein 1	0.051
STK24	serine/threonine kinase 24	0.051
HMGB2	high mobility group box 2	0.050
CCNE2	cyclin E2	0.050
BAD	BCL2-associated agonist of cell death	0.049
AXIN2	axin 2	0.049
CAPN2	calpain 2, (m/II) large subunit	0.049
LTK	leukocyte receptor tyrosine kinase	0.049
GRB2	growth factor receptor-bound protein 2	0.048
GSK3B	glycogen synthase kinase 3 beta	0.046
TMSB4X	thymosin beta 4, X-linked	0.046
MARK1	MAP/microtubule affinity-regulating kinase 1	0.044	Worm
CDT1	chromatin licensing and DNA replication factor 1	0.044
GPSM2	G-protein signaling modulator 2	0.044	Fly
LRCH1	leucine-rich repeats and calponin homology (CH) domain containing 1	0.044
CHD6	chromodomain helicase DNA binding protein 6	0.043
PNMA2	paraneoplastic antigen MA2	0.043
EGF	epidermal growth factor	0.042
DICER1	dicer 1, ribonuclease type III	0.042
FGFR1	fibroblast growth factor receptor 1	0.042
UTRN	utrophin	0.042
BCR	breakpoint cluster region	0.041
CMIP	c-Maf-inducing protein	0.041
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.041
A1BG	alpha-1-B glycoprotein	0.040
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.040
ZFP28	zinc finger protein 28 homolog (mouse)	0.040
GRB14	growth factor receptor-bound protein 14	0.040
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.039
CCDC115	coiled-coil domain containing 115	0.039
KIAA0889	KIAA0889	0.039
RGS19	regulator of G-protein signaling 19	0.038
USHBP1	Usher syndrome 1C binding protein 1	0.038
ANGPT2	angiopoietin 2	0.038
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.037
CCNA1	cyclin A1	0.037	Fly
GLIS2	GLIS family zinc finger 2	0.037
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.036
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.036
LAD1	ladinin 1	0.036
C22orf39	chromosome 22 open reading frame 39	0.034
COL4A5	collagen, type IV, alpha 5	0.034
PDE4DIP	phosphodiesterase 4D interacting protein	0.034
ALAS1	aminolevulinate, delta-, synthase 1	0.034
RHPN2	rhophilin, Rho GTPase binding protein 2	0.034
NUMB	numb homolog (Drosophila)	0.034	Fly
NTF3	neurotrophin 3	0.033
CKS2	CDC28 protein kinase regulatory subunit 2	0.033
SDF4	stromal cell derived factor 4	0.033
CELF2	CUGBP, Elav-like family member 2	0.033
FKBP8	FK506 binding protein 8, 38kDa	0.033
TUBA1A	tubulin, alpha 1a	0.033
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.033
HDAC7	histone deacetylase 7	0.033
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.032
DOCK8	dedicator of cytokinesis 8	0.032
OSBPL3	oxysterol binding protein-like 3	0.032
USP50	ubiquitin specific peptidase 50	0.031
ZNF431	zinc finger protein 431	0.031
KRT14	keratin 14	0.031
SH2D3A	SH2 domain containing 3A	0.031
NCF1	neutrophil cytosolic factor 1	0.031
WEE1	WEE1 homolog (S. pombe)	0.031
MT1A	metallothionein 1A	0.031
INCENP	inner centromere protein antigens 135/155kDa	0.030
LRRK2	leucine-rich repeat kinase 2	0.030
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.030
TUBB2B	tubulin, beta 2B	0.030
UNC119	unc-119 homolog (C. elegans)	0.029
ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	0.029
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.029
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.029
NCKAP1	NCK-associated protein 1	0.029
WDR6	WD repeat domain 6	0.028
ANLN	anillin, actin binding protein	0.028
TPD52L1	tumor protein D52-like 1	0.028
CDK6	cyclin-dependent kinase 6	0.028
RALGPS2	Ral GEF with PH domain and SH3 binding motif 2	0.028
QRICH2	glutamine rich 2	0.027
SNRK	SNF related kinase	0.027
FAM101B	family with sequence similarity 101, member B	0.027
MLL4	myeloid/lymphoid or mixed-lineage leukemia 4	0.027
BANP	BTG3 associated nuclear protein	0.027
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.027
RND3	Rho family GTPase 3	0.027
WIPF1	WAS/WASL interacting protein family, member 1	0.027
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.026
FHL1	four and a half LIM domains 1	0.026
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.026
RCOR1	REST corepressor 1	0.026
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.026
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.026
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.026
AMOTL2	angiomotin like 2	0.025
S100A8	S100 calcium binding protein A8	0.025
LMTK3	lemur tyrosine kinase 3	0.025
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.025
SORBS1	sorbin and SH3 domain containing 1	0.025
ESRP2	epithelial splicing regulatory protein 2	0.025
PGAM5	phosphoglycerate mutase family member 5	0.025
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.025
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.025
CDK14	cyclin-dependent kinase 14	0.025
PCDH1	protocadherin 1	0.025
DEDD	death effector domain containing	0.025
CXCR5	chemokine (C-X-C motif) receptor 5	0.024
INPP5K	inositol polyphosphate-5-phosphatase K	0.024
PRKCG	protein kinase C, gamma	0.024
PLEKHO1	pleckstrin homology domain containing, family O member 1	0.024
PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	0.024	Fly
CADM3	cell adhesion molecule 3	0.024
RGS14	regulator of G-protein signaling 14	0.024	Fly
EXO1	exonuclease 1	0.024
ASB13	ankyrin repeat and SOCS box containing 13	0.024
ENOX1	ecto-NOX disulfide-thiol exchanger 1	0.024
LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2	0.024
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.023
EGR3	early growth response 3	0.023
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.023
RBBP8	retinoblastoma binding protein 8	0.023
CAMKV	CaM kinase-like vesicle-associated	0.023
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.023
LRCH3	leucine-rich repeats and calponin homology (CH) domain containing 3	0.023
GPRIN2	G protein regulated inducer of neurite outgrowth 2	0.023
WDYHV1	WDYHV motif containing 1	0.023
NGFR	nerve growth factor receptor	0.023
DOK5	docking protein 5	0.023
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.023
CHGB	chromogranin B (secretogranin 1)	0.023
ING5	inhibitor of growth family, member 5	0.022
DNAH17	dynein, axonemal, heavy chain 17	0.022
FOXO3	forkhead box O3	0.022
ZBTB16	zinc finger and BTB domain containing 16	0.022	Mouse
TGFA	transforming growth factor, alpha	0.022
ARL11	ADP-ribosylation factor-like 11	0.022
SYN2	synapsin II	0.022
SPRED1	sprouty-related, EVH1 domain containing 1	0.022
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.022
AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	0.022
RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7	0.021
GSTM4	glutathione S-transferase mu 4	0.021
ZC3H7B	zinc finger CCCH-type containing 7B	0.021
EXT2	exostosin 2	0.021
FRMD6	FERM domain containing 6	0.021
THNSL2	threonine synthase-like 2 (S. cerevisiae)	0.021
TRPV6	transient receptor potential cation channel, subfamily V, member 6	0.021
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.021
CPNE2	copine II	0.021
SCLT1	sodium channel and clathrin linker 1	0.021
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.021
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.021
PIM1	pim-1 oncogene	0.021
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.021
INCA1	inhibitor of CDK, cyclin A1 interacting protein 1	0.020
FBN3	fibrillin 3	0.020
CAPNS1	calpain, small subunit 1	0.020
KDM1A	lysine (K)-specific demethylase 1A	0.020
HMGXB3	HMG box domain containing 3	0.020
TJP2	tight junction protein 2 (zona occludens 2)	0.020
PKNOX2	PBX/knotted 1 homeobox 2	0.020
GNG12	guanine nucleotide binding protein (G protein), gamma 12	0.020
GATA2	GATA binding protein 2	0.020
ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16	0.019
PLS3	plastin 3	0.019
GAB2	GRB2-associated binding protein 2	0.019
PAK7	p21 protein (Cdc42/Rac)-activated kinase 7	0.019
ATXN2L	ataxin 2-like	0.019
KRT5	keratin 5	0.019
CDK17	cyclin-dependent kinase 17	0.019
ANKS1A	ankyrin repeat and sterile alpha motif domain containing 1A	0.019
RPP14	ribonuclease P/MRP 14kDa subunit	0.019
TGFBR1	transforming growth factor, beta receptor 1	0.019
ADCY1	adenylate cyclase 1 (brain)	0.019
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.019
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.019
CCDC109B	coiled-coil domain containing 109B	0.019
C9orf40	chromosome 9 open reading frame 40	0.019
SUMF2	sulfatase modifying factor 2	0.019
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.019
PRC1	protein regulator of cytokinesis 1	0.019
RIPK3	receptor-interacting serine-threonine kinase 3	0.019
BMP2K	BMP2 inducible kinase	0.019
HIPK2	homeodomain interacting protein kinase 2	0.019
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.019
MAMLD1	mastermind-like domain containing 1	0.018
TRAF4	TNF receptor-associated factor 4	0.018
KATNA1	katanin p60 (ATPase containing) subunit A 1	0.018
PLP1	proteolipid protein 1	0.018
ARHGAP21	Rho GTPase activating protein 21	0.018
EDNRA	endothelin receptor type A	0.018
TMEM50A	transmembrane protein 50A	0.018
PAFAH1B2	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	0.018
PML	promyelocytic leukemia	0.018
SAMD3	sterile alpha motif domain containing 3	0.018
TBC1D4	TBC1 domain family, member 4	0.018
LASP1	LIM and SH3 protein 1	0.018
CNTFR	ciliary neurotrophic factor receptor	0.018
DOK6	docking protein 6	0.018
SIPA1	signal-induced proliferation-associated 1	0.017
KIAA1967	KIAA1967	0.017
DENND5A	DENN/MADD domain containing 5A	0.017
GAP43	growth associated protein 43	0.017
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.017
ARHGEF4	Rho guanine nucleotide exchange factor (GEF) 4	0.017
IQGAP2	IQ motif containing GTPase activating protein 2	0.017
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.017	Worm
MAP2K5	mitogen-activated protein kinase kinase 5	0.017
SEPT4	septin 4	0.017
BAG2	BCL2-associated athanogene 2	0.017
TLN1	talin 1	0.017
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.017
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.017
MYO9A	myosin IXA	0.017
TGIF1	TGFB-induced factor homeobox 1	0.017
TRAF7	TNF receptor-associated factor 7	0.017
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.017
LMNB1	lamin B1	0.017
ACTN4	actinin, alpha 4	0.017
RASAL2	RAS protein activator like 2	0.017
MTNR1A	melatonin receptor 1A	0.017
PTPRD	protein tyrosine phosphatase, receptor type, D	0.017
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.017
TRIP10	thyroid hormone receptor interactor 10	0.017
PTPRO	protein tyrosine phosphatase, receptor type, O	0.017
CGN	cingulin	0.017
OLFM1	olfactomedin 1	0.017
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.017
KBTBD2	kelch repeat and BTB (POZ) domain containing 2	0.016
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.016
UNC5C	unc-5 homolog C (C. elegans)	0.016
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.016
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.016
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.016
STAT5A	signal transducer and activator of transcription 5A	0.016
IRS4	insulin receptor substrate 4	0.016	Fly
RABGEF1	RAB guanine nucleotide exchange factor (GEF) 1	0.016
ARHGEF5	Rho guanine nucleotide exchange factor (GEF) 5	0.016
CDC42EP2	CDC42 effector protein (Rho GTPase binding) 2	0.016
YAP1	Yes-associated protein 1	0.016
DSP	desmoplakin	0.016
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.016
PIK3CD	phosphoinositide-3-kinase, catalytic, delta polypeptide	0.016
ZCCHC8	zinc finger, CCHC domain containing 8	0.016
TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	0.016
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.016
ANKLE2	ankyrin repeat and LEM domain containing 2	0.016
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.016
SKIL	SKI-like oncogene	0.016
PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide	0.016
APLP1	amyloid beta (A4) precursor-like protein 1	0.016
RGS3	regulator of G-protein signaling 3	0.016
ING1	inhibitor of growth family, member 1	0.016
S1PR1	sphingosine-1-phosphate receptor 1	0.016
CDV3	CDV3 homolog (mouse)	0.015
GTF2E2	general transcription factor IIE, polypeptide 2, beta 34kDa	0.015
TUBB4	tubulin, beta 4	0.015
PRDM4	PR domain containing 4	0.015
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.015
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.015
PTPRN	protein tyrosine phosphatase, receptor type, N	0.015
TIAM1	T-cell lymphoma invasion and metastasis 1	0.015
ACCN2	amiloride-sensitive cation channel 2, neuronal	0.015
VAV2	vav 2 guanine nucleotide exchange factor	0.015
PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)	0.015
PPP1R14A	protein phosphatase 1, regulatory (inhibitor) subunit 14A	0.015
SDCBP2	syndecan binding protein (syntenin) 2	0.015
OGFR	opioid growth factor receptor	0.015
PAFAH1B3	platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)	0.015
EIF5	eukaryotic translation initiation factor 5	0.015
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.015
GDF9	growth differentiation factor 9	0.015
CSAD	cysteine sulfinic acid decarboxylase	0.015
H3F3B	H3 histone, family 3B (H3.3B)	0.015
THPO	thrombopoietin	0.015
MED31	mediator complex subunit 31	0.015
PHLDB1	pleckstrin homology-like domain, family B, member 1	0.015
MASTL	microtubule associated serine/threonine kinase-like	0.015
BMP4	bone morphogenetic protein 4	0.015
SIPA1L3	signal-induced proliferation-associated 1 like 3	0.015
NPAS3	neuronal PAS domain protein 3	0.015
MCPH1	microcephalin 1	0.015
RBL2	retinoblastoma-like 2 (p130)	0.015
HOXA6	homeobox A6	0.015
KLF9	Kruppel-like factor 9	0.015
PRKCQ	protein kinase C, theta	0.015
NCF4	neutrophil cytosolic factor 4, 40kDa	0.014
GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.014
L3MBTL3	l(3)mbt-like 3 (Drosophila)	0.014
CNTN1	contactin 1	0.014
WWC1	WW and C2 domain containing 1	0.014
SHROOM3	shroom family member 3	0.014
RAB3A	RAB3A, member RAS oncogene family	0.014
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.014
SMAD3	SMAD family member 3	0.014
BAIAP2	BAI1-associated protein 2	0.014
ZNF410	zinc finger protein 410	0.014
COL4A1	collagen, type IV, alpha 1	0.014
DAPK3	death-associated protein kinase 3	0.014
CAMK1	calcium/calmodulin-dependent protein kinase I	0.014
LMTK2	lemur tyrosine kinase 2	0.014
CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	0.014
AKAP12	A kinase (PRKA) anchor protein 12	0.014
GPM6B	glycoprotein M6B	0.014
FAM46A	family with sequence similarity 46, member A	0.014
CHMP7	CHMP family, member 7	0.014
GNB5	guanine nucleotide binding protein (G protein), beta 5	0.014
GNG4	guanine nucleotide binding protein (G protein), gamma 4	0.014	Fly
NUMBL	numb homolog (Drosophila)-like	0.014	Fly
LARGE	like-glycosyltransferase	0.014
KRT1	keratin 1	0.014
SKA2	spindle and kinetochore associated complex subunit 2	0.014
SCRG1	stimulator of chondrogenesis 1	0.014
PAX6	paired box 6	0.014
ARL3	ADP-ribosylation factor-like 3	0.014
RAI14	retinoic acid induced 14	0.014
MCM3AP	minichromosome maintenance complex component 3 associated protein	0.014
FXYD2	FXYD domain containing ion transport regulator 2	0.014
PTPRT	protein tyrosine phosphatase, receptor type, T	0.014
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.014
SCEL	sciellin	0.014
LPHN3	latrophilin 3	0.014
SYNJ2	synaptojanin 2	0.014
C1orf106	chromosome 1 open reading frame 106	0.014
SAMD4B	sterile alpha motif domain containing 4B	0.014
UBB	ubiquitin B	0.014
SGCE	sarcoglycan, epsilon	0.014
PLCE1	phospholipase C, epsilon 1	0.014
APP	amyloid beta (A4) precursor protein	0.014
ORC1	origin recognition complex, subunit 1	0.014
PER2	period homolog 2 (Drosophila)	0.014
BAI2	brain-specific angiogenesis inhibitor 2	0.014
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.014
CA2	carbonic anhydrase II	0.014
RHOB	ras homolog gene family, member B	0.014
ADAM23	ADAM metallopeptidase domain 23	0.014
BLK	B lymphoid tyrosine kinase	0.013
RAB6B	RAB6B, member RAS oncogene family	0.013
RAB40C	RAB40C, member RAS oncogene family	0.013
GNAZ	guanine nucleotide binding protein (G protein), alpha z polypeptide	0.013
EFNA3	ephrin-A3	0.013
C6orf204	chromosome 6 open reading frame 204	0.013
KIF14	kinesin family member 14	0.013
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.013
ST8SIA4	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4	0.013
CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3	0.013
GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O	0.013
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.013
CSK	c-src tyrosine kinase	0.013
PPFIBP1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	0.013
PIGA	phosphatidylinositol glycan anchor biosynthesis, class A	0.013
BRDT	bromodomain, testis-specific	0.013
GAN	gigaxonin	0.013
TTC25	tetratricopeptide repeat domain 25	0.013
HDAC5	histone deacetylase 5	0.013
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.013
INADL	InaD-like (Drosophila)	0.013
CSNK1G2	casein kinase 1, gamma 2	0.013
KCNB1	potassium voltage-gated channel, Shab-related subfamily, member 1	0.013
RAI1	retinoic acid induced 1	0.013
GNAS	GNAS complex locus	0.013
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.013
FAM82A2	family with sequence similarity 82, member A2	0.013
DPP6	dipeptidyl-peptidase 6	0.013
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.013
KCNK3	potassium channel, subfamily K, member 3	0.013
HIST1H1B	histone cluster 1, H1b	0.013
CTTN	cortactin	0.013
SSTR2	somatostatin receptor 2	0.013
SIK2	salt-inducible kinase 2	0.013
TNK2	tyrosine kinase, non-receptor, 2	0.013
EPHA2	EPH receptor A2	0.013
E2F4	E2F transcription factor 4, p107/p130-binding	0.013
CORO1C	coronin, actin binding protein, 1C	0.013
EPB41L3	erythrocyte membrane protein band 4.1-like 3	0.013
SIK3	SIK family kinase 3	0.013
KIAA0930	KIAA0930	0.013
FLOT2	flotillin 2	0.013
ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.013
PCP4	Purkinje cell protein 4	0.013
POU3F1	POU class 3 homeobox 1	0.013
ZC3H10	zinc finger CCCH-type containing 10	0.013
SCN2A	sodium channel, voltage-gated, type II, alpha subunit	0.013
ETNK2	ethanolamine kinase 2	0.013
SORT1	sortilin 1	0.013
LRRC61	leucine rich repeat containing 61	0.013
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.013
SEZ6L	seizure related 6 homolog (mouse)-like	0.013
BEX1	brain expressed, X-linked 1	0.013
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.013
NPY	neuropeptide Y	0.013
AP3B2	adaptor-related protein complex 3, beta 2 subunit	0.013
LMO7	LIM domain 7	0.013
UIMC1	ubiquitin interaction motif containing 1	0.013
KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4	0.012
TCTEX1D2	Tctex1 domain containing 2	0.012
PPM1E	protein phosphatase, Mg2+/Mn2+ dependent, 1E	0.012
RENBP	renin binding protein	0.012
RIMS2	regulating synaptic membrane exocytosis 2	0.012
FRS2	fibroblast growth factor receptor substrate 2	0.012
GAS7	growth arrest-specific 7	0.012
IGHMBP2	immunoglobulin mu binding protein 2	0.012
ARHGAP32	Rho GTPase activating protein 32	0.012
BTG3	BTG family, member 3	0.012
EZR	ezrin	0.012
AGTR1	angiotensin II receptor, type 1	0.012
PPP1R13B	protein phosphatase 1, regulatory (inhibitor) subunit 13B	0.012
TAGLN3	transgelin 3	0.012
GLYCTK	glycerate kinase	0.012
HIP1R	huntingtin interacting protein 1 related	0.012
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.012
REEP2	receptor accessory protein 2	0.012
CTNNAL1	catenin (cadherin-associated protein), alpha-like 1	0.012
CISH	cytokine inducible SH2-containing protein	0.012
ASPA	aspartoacylase	0.012
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.012	Worm
GFRA2	GDNF family receptor alpha 2	0.012
CDKN3	cyclin-dependent kinase inhibitor 3	0.012
KRT16	keratin 16	0.012
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.012
PSD4	pleckstrin and Sec7 domain containing 4	0.012
NPY1R	neuropeptide Y receptor Y1	0.012
MATK	megakaryocyte-associated tyrosine kinase	0.012
FANCE	Fanconi anemia, complementation group E	0.012
CCDC106	coiled-coil domain containing 106	0.012
FCHO2	FCH domain only 2	0.012
RGS6	regulator of G-protein signaling 6	0.012
ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif, 4	0.012
LIN54	lin-54 homolog (C. elegans)	0.012
RGS12	regulator of G-protein signaling 12	0.012	Fly
NIT1	nitrilase 1	0.012
HIST1H1E	histone cluster 1, H1e	0.012
SIPA1L1	signal-induced proliferation-associated 1 like 1	0.012
HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	0.012
ZFAND2B	zinc finger, AN1-type domain 2B	0.012
PER1	period homolog 1 (Drosophila)	0.012
SEMA6B	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B	0.012
CHST10	carbohydrate sulfotransferase 10	0.012
TMEM59L	transmembrane protein 59-like	0.012
LIMD2	LIM domain containing 2	0.012
TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator	0.012
GMNN	geminin, DNA replication inhibitor	0.012
ZNF135	zinc finger protein 135	0.012
EPHA5	EPH receptor A5	0.012
SIX5	SIX homeobox 5	0.012
CNR1	cannabinoid receptor 1 (brain)	0.012
HIST1H1A	histone cluster 1, H1a	0.012
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.012
PRKCE	protein kinase C, epsilon	0.012
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.012
NRIP3	nuclear receptor interacting protein 3	0.012
ADAP1	ArfGAP with dual PH domains 1	0.012
MNS1	meiosis-specific nuclear structural 1	0.012
TP63	tumor protein p63	0.012
CASZ1	castor zinc finger 1	0.012
HSPA2	heat shock 70kDa protein 2	0.012
PDE10A	phosphodiesterase 10A	0.012
ASTN1	astrotactin 1	0.012
DBC1	deleted in bladder cancer 1	0.012
PPP2R3B	protein phosphatase 2, regulatory subunit B'', beta	0.012
KLHL25	kelch-like 25 (Drosophila)	0.012
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.012
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.012
SKA1	spindle and kinetochore associated complex subunit 1	0.012
SOS2	son of sevenless homolog 2 (Drosophila)	0.012
AGFG1	ArfGAP with FG repeats 1	0.012
AFF2	AF4/FMR2 family, member 2	0.012
LPPR3	lipid phosphate phosphatase-related protein type 3	0.012
DCLK2	doublecortin-like kinase 2	0.012
RGS7	regulator of G-protein signaling 7	0.012
CHRNE	cholinergic receptor, nicotinic, epsilon	0.012
CYB5R2	cytochrome b5 reductase 2	0.012
FGF8	fibroblast growth factor 8 (androgen-induced)	0.012
KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	0.012
DONSON	downstream neighbor of SON	0.012
GMEB1	glucocorticoid modulatory element binding protein 1	0.012
MVK	mevalonate kinase	0.012
SEPT3	septin 3	0.012
RAP2C	RAP2C, member of RAS oncogene family	0.012
SEPT5	septin 5	0.012
KCNIP1	Kv channel interacting protein 1	0.012
PVRL3	poliovirus receptor-related 3	0.012
AMOTL1	angiomotin like 1	0.012
APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B	0.012
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.012
KCND3	potassium voltage-gated channel, Shal-related subfamily, member 3	0.012
PLIN3	perilipin 3	0.012
CIDEA	cell death-inducing DFFA-like effector a	0.012
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.011
STK38	serine/threonine kinase 38	0.011
PTPRG	protein tyrosine phosphatase, receptor type, G	0.011
LRCH4	leucine-rich repeats and calponin homology (CH) domain containing 4	0.011
CAMK2B	calcium/calmodulin-dependent protein kinase II beta	0.011
EPB49	erythrocyte membrane protein band 4.9 (dematin)	0.011
DOK4	docking protein 4	0.011
CTTNBP2	cortactin binding protein 2	0.011
DOCK6	dedicator of cytokinesis 6	0.011
CCL27	chemokine (C-C motif) ligand 27	0.011
IL9R	interleukin 9 receptor	0.011
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.011
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.011
INA	internexin neuronal intermediate filament protein, alpha	0.011
NOVA2	neuro-oncological ventral antigen 2	0.011
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.011
GRIA2	glutamate receptor, ionotropic, AMPA 2	0.011
KLHL11	kelch-like 11 (Drosophila)	0.011
CCDC130	coiled-coil domain containing 130	0.011
FAM189A2	family with sequence similarity 189, member A2	0.011
RAB11FIP5	RAB11 family interacting protein 5 (class I)	0.011
SMOX	spermine oxidase	0.011
NOVA1	neuro-oncological ventral antigen 1	0.011
GDF10	growth differentiation factor 10	0.011
NR6A1	nuclear receptor subfamily 6, group A, member 1	0.011
RPGR	retinitis pigmentosa GTPase regulator	0.011
GARNL3	GTPase activating Rap/RanGAP domain-like 3	0.011
WIF1	WNT inhibitory factor 1	0.011
CDR1	cerebellar degeneration-related protein 1, 34kDa	0.011
BCORL1	BCL6 corepressor-like 1	0.011
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.011
FCHO1	FCH domain only 1	0.011
GABRA3	gamma-aminobutyric acid (GABA) A receptor, alpha 3	0.011
ZMIZ1	zinc finger, MIZ-type containing 1	0.011
HEY2	hairy/enhancer-of-split related with YRPW motif 2	0.011
TGFBR3	transforming growth factor, beta receptor III	0.011
EIF4ENIF1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.011
SCG2	secretogranin II	0.011
DAP	death-associated protein	0.011
CSRNP3	cysteine-serine-rich nuclear protein 3	0.011
SPIRE1	spire homolog 1 (Drosophila)	0.011
ACTR1A	ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)	0.011
COL6A3	collagen, type VI, alpha 3	0.011
STAMBPL1	STAM binding protein-like 1	0.011
CAPN1	calpain 1, (mu/I) large subunit	0.011
NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein	0.011
RELN	reelin	0.011
ARNTL2	aryl hydrocarbon receptor nuclear translocator-like 2	0.011
GNGT1	guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1	0.011
CPNE6	copine VI (neuronal)	0.011
RASD1	RAS, dexamethasone-induced 1	0.011
RGS5	regulator of G-protein signaling 5	0.011
BDNF	brain-derived neurotrophic factor	0.011
PVRL1	poliovirus receptor-related 1 (herpesvirus entry mediator C)	0.011
SMO	smoothened homolog (Drosophila)	0.011
CDCA8	cell division cycle associated 8	0.011
KLF7	Kruppel-like factor 7 (ubiquitous)	0.011
CNTNAP2	contactin associated protein-like 2	0.011
CORO2B	coronin, actin binding protein, 2B	0.011
PTCH1	patched 1	0.011
RGS20	regulator of G-protein signaling 20	0.011
HS6ST1	heparan sulfate 6-O-sulfotransferase 1	0.011
OPHN1	oligophrenin 1	0.011
ZCCHC14	zinc finger, CCHC domain containing 14	0.011
LRRFIP2	leucine rich repeat (in FLII) interacting protein 2	0.011
GNG3	guanine nucleotide binding protein (G protein), gamma 3	0.011	Fly
FARP2	FERM, RhoGEF and pleckstrin domain protein 2	0.011
TRAF3IP2	TRAF3 interacting protein 2	0.011
ARID3A	AT rich interactive domain 3A (BRIGHT-like)	0.011
CCDC9	coiled-coil domain containing 9	0.011
STX19	syntaxin 19	0.011
EEF1A2	eukaryotic translation elongation factor 1 alpha 2	0.011
SNX24	sorting nexin 24	0.011
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.011
ALK	anaplastic lymphoma receptor tyrosine kinase	0.011
TEX28	testis expressed 28	0.011
TSGA13	testis specific, 13	0.011
CNNM1	cyclin M1	0.011
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.011
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.011
KIF3C	kinesin family member 3C	0.011
CENPE	centromere protein E, 312kDa	0.011
PLAGL1	pleiomorphic adenoma gene-like 1	0.011
PMPCB	peptidase (mitochondrial processing) beta	0.011
DAGLA	diacylglycerol lipase, alpha	0.011
NPAS2	neuronal PAS domain protein 2	0.011
NRGN	neurogranin (protein kinase C substrate, RC3)	0.011
RORB	RAR-related orphan receptor B	0.011
GAGE8	G antigen 8	0.011
SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.011
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.011
HIST1H4L	histone cluster 1, H4l	0.011
A2M	alpha-2-macroglobulin	0.011
ECT2	epithelial cell transforming sequence 2 oncogene	0.011
CRY2	cryptochrome 2 (photolyase-like)	0.011
ST5	suppression of tumorigenicity 5	0.011
RYR3	ryanodine receptor 3	0.011
DLL3	delta-like 3 (Drosophila)	0.011
RFX2	regulatory factor X, 2 (influences HLA class II expression)	0.011
SCAMP5	secretory carrier membrane protein 5	0.011
MCC	mutated in colorectal cancers	0.011
PPP2R3A	protein phosphatase 2, regulatory subunit B'', alpha	0.011
ITGB4	integrin, beta 4	0.011
NKD2	naked cuticle homolog 2 (Drosophila)	0.011
ANKRD42	ankyrin repeat domain 42	0.011
USP42	ubiquitin specific peptidase 42	0.011
CUL9	cullin 9	0.011
C13orf15	chromosome 13 open reading frame 15	0.011
SORCS3	sortilin-related VPS10 domain containing receptor 3	0.011
FAM9A	family with sequence similarity 9, member A	0.011
VIPR2	vasoactive intestinal peptide receptor 2	0.011
STK38L	serine/threonine kinase 38 like	0.011
EYA4	eyes absent homolog 4 (Drosophila)	0.011
FUT4	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)	0.011
CCBL1	cysteine conjugate-beta lyase, cytoplasmic	0.011
ANTXR2	anthrax toxin receptor 2	0.011
KDM4D	lysine (K)-specific demethylase 4D	0.011
LIMK2	LIM domain kinase 2	0.011