IMP: Integrative Multi-species Prediction

Homo sapiens

223 genes annotated in human

musculoskeletal system disease

DOID:17

A disease of anatomical entity that occurs in the muscular and/or skeletal system.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "musculoskeletal system disease"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "musculoskeletal system disease" (in gray)

Name	Description	Probability	Func Analog Organism
TRIM63	tripartite motif containing 63	1.000
TTN	titin	1.000
FLNC	filamin C, gamma	1.000
NEB	nebulin	1.000
SUN2	Sad1 and UNC84 domain containing 2	1.000
BMPR1A	bone morphogenetic protein receptor, type IA	1.000	Human
TNNI1	troponin I type 1 (skeletal, slow)	1.000	Human
TNNC1	troponin C type 1 (slow)	1.000
MYOZ1	myozenin 1	1.000	Human
SUN1	Sad1 and UNC84 domain containing 1	0.999
HSPB8	heat shock 22kDa protein 8	0.999	Human
COL6A2	collagen, type VI, alpha 2	0.998
COL1A1	collagen, type I, alpha 1	0.998
GMPPA	GDP-mannose pyrophosphorylase A	0.997
FGF1	fibroblast growth factor 1 (acidic)	0.997
FLNA	filamin A, alpha	0.996	Human
SGCD	sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)	0.996
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.995	Human
HSPB1	heat shock 27kDa protein 1	0.995
TPM2	tropomyosin 2 (beta)	0.994
ACTN2	actinin, alpha 2	0.994
ESR2	estrogen receptor 2 (ER beta)	0.993
TCAP	titin-cap (telethonin)	0.993
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.992
DSG2	desmoglein 2	0.992
FHL2	four and a half LIM domains 2	0.992
LDB3	LIM domain binding 3	0.990
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.990	Human
COL1A2	collagen, type I, alpha 2	0.986
CRYAB	crystallin, alpha B	0.985
DSC2	desmocollin 2	0.985
COL5A1	collagen, type V, alpha 1	0.983
PDLIM7	PDZ and LIM domain 7 (enigma)	0.983	Human
TNNT2	troponin T type 2 (cardiac)	0.981
DSP	desmoplakin	0.980
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.973	Human
JUP	junction plakoglobin	0.967
HSPB2	heat shock 27kDa protein 2	0.967	Human
TJP1	tight junction protein 1 (zona occludens 1)	0.966
HLA-DMB	major histocompatibility complex, class II, DM beta	0.964
DTNA	dystrobrevin, alpha	0.963
COL6A1	collagen, type VI, alpha 1	0.963
AKAP12	A kinase (PRKA) anchor protein 12	0.962
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.961	Human
CSRP3	cysteine and glycine-rich protein 3 (cardiac LIM protein)	0.961
FLNB	filamin B, beta	0.960
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.958
RBPMS	RNA binding protein with multiple splicing	0.956
COL3A1	collagen, type III, alpha 1	0.955
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.952	Human
PSEN1	presenilin 1	0.951
MYBPC2	myosin binding protein C, fast type	0.949
TNNT3	troponin T type 3 (skeletal, fast)	0.941
ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1	0.939
BGN	biglycan	0.935
DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)	0.934
RIN3	Ras and Rab interactor 3	0.926
ACTA1	actin, alpha 1, skeletal muscle	0.924	Human
MYH7	myosin, heavy chain 7, cardiac muscle, beta	0.923
MYH6	myosin, heavy chain 6, cardiac muscle, alpha	0.919
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.917
TNNT1	troponin T type 1 (skeletal, slow)	0.914	Human
PKP2	plakophilin 2	0.905
MYL2	myosin, light chain 2, regulatory, cardiac, slow	0.905
PDE4DIP	phosphodiesterase 4D interacting protein	0.905
PSEN2	presenilin 2 (Alzheimer disease 4)	0.899
MYL1	myosin, light chain 1, alkali; skeletal, fast	0.896	Human
DES	desmin	0.894
TNNI2	troponin I type 2 (skeletal, fast)	0.894
FGFR2	fibroblast growth factor receptor 2	0.892
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.890	Human
DDR2	discoidin domain receptor tyrosine kinase 2	0.888
COL5A2	collagen, type V, alpha 2	0.887
COL4A1	collagen, type IV, alpha 1	0.882
UBQLN4	ubiquilin 4	0.878
TARDBP	TAR DNA binding protein	0.875
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.867
PDIA3	protein disulfide isomerase family A, member 3	0.865
DNM1	dynamin 1	0.859	Human
CKM	creatine kinase, muscle	0.856
FSTL1	follistatin-like 1	0.846
LOX	lysyl oxidase	0.846
PKP4	plakophilin 4	0.838	Human
MYLPF	myosin light chain, phosphorylatable, fast skeletal muscle	0.837	Human
CHRD	chordin	0.834
ITGB4	integrin, beta 4	0.833
HLA-C	major histocompatibility complex, class I, C	0.828
MTMR12	myotubularin related protein 12	0.819	Human
BMP2	bone morphogenetic protein 2	0.818
SGCA	sarcoglycan, alpha (50kDa dystrophin-associated glycoprotein)	0.817
PDIA4	protein disulfide isomerase family A, member 4	0.811
HLA-A	major histocompatibility complex, class I, A	0.809
TPM1	tropomyosin 1 (alpha)	0.806
COX6A2	cytochrome c oxidase subunit VIa polypeptide 2	0.806
PTN	pleiotrophin	0.803
HNRNPA1	heterogeneous nuclear ribonucleoprotein A1	0.801
BMPR1B	bone morphogenetic protein receptor, type IB	0.795
UTRN	utrophin	0.791	Human
ACTN3	actinin, alpha 3	0.784
SMAD1	SMAD family member 1	0.782
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.759
MYH9	myosin, heavy chain 9, non-muscle	0.751
B2M	beta-2-microglobulin	0.749
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.746
TRIP6	thyroid hormone receptor interactor 6	0.723
CRELD2	cysteine-rich with EGF-like domains 2	0.720
CD247	CD247 molecule	0.718
MYH1	myosin, heavy chain 1, skeletal muscle, adult	0.708	Human
MYL3	myosin, light chain 3, alkali; ventricular, skeletal, slow	0.708
SMPX	small muscle protein, X-linked	0.699
MARK3	MAP/microtubule affinity-regulating kinase 3	0.697
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.695
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.692
FGF10	fibroblast growth factor 10	0.691
IL10RA	interleukin 10 receptor, alpha	0.690
DMD	dystrophin	0.687
KRT18	keratin 18	0.681
MYOZ2	myozenin 2	0.678
CASQ2	calsequestrin 2 (cardiac muscle)	0.672
MYBPC1	myosin binding protein C, slow type	0.661
CAV3	caveolin 3	0.657
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.656
GDF5	growth differentiation factor 5	0.655
CNN1	calponin 1, basic, smooth muscle	0.647
CD80	CD80 molecule	0.647
LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	0.645
FBN1	fibrillin 1	0.638	Human
TXNIP	thioredoxin interacting protein	0.635
COL4A2	collagen, type IV, alpha 2	0.628
COL11A1	collagen, type XI, alpha 1	0.627	Human
ITGA3	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)	0.605	Human
MYH2	myosin, heavy chain 2, skeletal muscle, adult	0.603
MYOM1	myomesin 1, 185kDa	0.602
RXRA	retinoid X receptor, alpha	0.598
CRYBB2	crystallin, beta B2	0.594
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.593	Human
CAPN3	calpain 3, (p94)	0.590
FHL3	four and a half LIM domains 3	0.586
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.580
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.579
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.579
MYOD1	myogenic differentiation 1	0.578	Human
HAP1	huntingtin-associated protein 1	0.568
BCL2L1	BCL2-like 1	0.564
SNTG2	syntrophin, gamma 2	0.561
ANKRD2	ankyrin repeat domain 2 (stretch responsive muscle)	0.558
RHOXF2	Rhox homeobox family, member 2	0.557
PLEC	plectin	0.556
TGFB3	transforming growth factor, beta 3	0.556
GPC1	glypican 1	0.555
HLA-F	major histocompatibility complex, class I, F	0.555
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.554
COL2A1	collagen, type II, alpha 1	0.554
PCOLCE	procollagen C-endopeptidase enhancer	0.552
LOXL1	lysyl oxidase-like 1	0.552
SETD8	SET domain containing (lysine methyltransferase) 8	0.550
HNRNPH3	heterogeneous nuclear ribonucleoprotein H3 (2H9)	0.548
FGF2	fibroblast growth factor 2 (basic)	0.547
SRPK3	SRSF protein kinase 3	0.536
MYL4	myosin, light chain 4, alkali; atrial, embryonic	0.530	Human
SVIL	supervillin	0.527
HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	0.526
CD86	CD86 molecule	0.517
TGFB1	transforming growth factor, beta 1	0.515
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.502
AEBP1	AE binding protein 1	0.498
HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)	0.496
ANGPTL2	angiopoietin-like 2	0.493
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.490	Human
KRT8	keratin 8	0.486
PXDN	peroxidasin homolog (Drosophila)	0.481
HR	hairless homolog (mouse)	0.478
COL18A1	collagen, type XVIII, alpha 1	0.475
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.472
TNNC2	troponin C type 2 (fast)	0.472	Human
RPL3L	ribosomal protein L3-like	0.471
COL6A3	collagen, type VI, alpha 3	0.468
SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	0.465
SMAD3	SMAD family member 3	0.461
HLA-G	major histocompatibility complex, class I, G	0.457
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.452
SYNM	synemin, intermediate filament protein	0.451	Human
LMNA	lamin A/C	0.448
XIRP1	xin actin-binding repeat containing 1	0.448
SKIL	SKI-like oncogene	0.446	Human
PGAM2	phosphoglycerate mutase 2 (muscle)	0.445
MYH11	myosin, heavy chain 11, smooth muscle	0.441
MYL9	myosin, light chain 9, regulatory	0.441	Human
ACTC1	actin, alpha, cardiac muscle 1	0.429
NRIP1	nuclear receptor interacting protein 1	0.425
CRYAA	crystallin, alpha A	0.424	Human
POSTN	periostin, osteoblast specific factor	0.419
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.418
DYSF	dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)	0.417
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.415
BMP7	bone morphogenetic protein 7	0.414	Human
NCSTN	nicastrin	0.413
UBQLN1	ubiquilin 1	0.412
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.408
BAG1	BCL2-associated athanogene	0.407
SNW1	SNW domain containing 1	0.403
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.394
LTBP4	latent transforming growth factor beta binding protein 4	0.391
MRC2	mannose receptor, C type 2	0.390
LMF2	lipase maturation factor 2	0.386
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.384
AKAP6	A kinase (PRKA) anchor protein 6	0.382
ENG	endoglin	0.382
FAP	fibroblast activation protein, alpha	0.373
TNNI3K	TNNI3 interacting kinase	0.371
CACNA1S	calcium channel, voltage-dependent, L type, alpha 1S subunit	0.371
HSPG2	heparan sulfate proteoglycan 2	0.366
TROAP	trophinin associated protein (tastin)	0.366
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.362
PYGM	phosphorylase, glycogen, muscle	0.362
CNTF	ciliary neurotrophic factor	0.360
LAMB1	laminin, beta 1	0.355
SFRP4	secreted frizzled-related protein 4	0.355
SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	0.355
LAMB2	laminin, beta 2 (laminin S)	0.355
RPN1	ribophorin I	0.354
IGFBP5	insulin-like growth factor binding protein 5	0.354
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.353
BBS10	Bardet-Biedl syndrome 10	0.347
COMP	cartilage oligomeric matrix protein	0.345
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.343
NBR1	neighbor of BRCA1 gene 1	0.342
FN1	fibronectin 1	0.341	Human
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.340
FKBP10	FK506 binding protein 10, 65 kDa	0.339
MYOT	myotilin	0.337
WISP1	WNT1 inducible signaling pathway protein 1	0.334
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.330
ACTA2	actin, alpha 2, smooth muscle, aorta	0.326	Human
TNNI3	troponin I type 3 (cardiac)	0.324
SLN	sarcolipin	0.324
SH2D1A	SH2 domain containing 1A	0.324
PTRF	polymerase I and transcript release factor	0.323
RARA	retinoic acid receptor, alpha	0.323
MYBPH	myosin binding protein H	0.322
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.318
RAPSN	receptor-associated protein of the synapse	0.312
CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)	0.310
SH3KBP1	SH3-domain kinase binding protein 1	0.305
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.303
ZFYVE9	zinc finger, FYVE domain containing 9	0.302
CLEC18C	C-type lectin domain family 18, member C	0.302
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.297
HSPB3	heat shock 27kDa protein 3	0.295	Human
FBLN2	fibulin 2	0.295
COL8A2	collagen, type VIII, alpha 2	0.294	Human
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.290
TGFB2	transforming growth factor, beta 2	0.288	Human
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.285
CTNNBIP1	catenin, beta interacting protein 1	0.285
C1orf93	chromosome 1 open reading frame 93	0.280
TGFBR1	transforming growth factor, beta receptor 1	0.280	Human
P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	0.279
OBSL1	obscurin-like 1	0.277
ANK1	ankyrin 1, erythrocytic	0.275
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.274
RUNX1	runt-related transcription factor 1	0.272	Human
MFAP2	microfibrillar-associated protein 2	0.268
PRRX1	paired related homeobox 1	0.267
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.265	Human
SMAD4	SMAD family member 4	0.263
MAP2K1	mitogen-activated protein kinase kinase 1	0.261
GSK3B	glycogen synthase kinase 3 beta	0.261
TAPBP	TAP binding protein (tapasin)	0.261
SYNPO2L	synaptopodin 2-like	0.260
MRPL41	mitochondrial ribosomal protein L41	0.259
MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	0.256
HOXA9	homeobox A9	0.255
MSX1	msh homeobox 1	0.254	Human
PDLIM3	PDZ and LIM domain 3	0.253	Human
MAN1B1	mannosidase, alpha, class 1B, member 1	0.252
ZHX1	zinc fingers and homeoboxes 1	0.252
SRPX	sushi-repeat containing protein, X-linked	0.251
SMTN	smoothelin	0.250
MXRA5	matrix-remodelling associated 5	0.248
KCNA5	potassium voltage-gated channel, shaker-related subfamily, member 5	0.248
LARP1	La ribonucleoprotein domain family, member 1	0.246
ADAM12	ADAM metallopeptidase domain 12	0.245
HNRNPR	heterogeneous nuclear ribonucleoprotein R	0.244
MYH4	myosin, heavy chain 4, skeletal muscle	0.241	Human
JPH2	junctophilin 2	0.241
BAD	BCL2-associated agonist of cell death	0.239
CSPG4	chondroitin sulfate proteoglycan 4	0.239
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.234
SCN4A	sodium channel, voltage-gated, type IV, alpha subunit	0.232
LEPREL4	leprecan-like 4	0.232
COL5A3	collagen, type V, alpha 3	0.229	Human
EMILIN1	elastin microfibril interfacer 1	0.229
FBP2	fructose-1,6-bisphosphatase 2	0.227
NCOR1	nuclear receptor corepressor 1	0.227
APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	0.225
LEPREL2	leprecan-like 2	0.224	Human
HRC	histidine rich calcium binding protein	0.223
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.222
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.221
COL7A1	collagen, type VII, alpha 1	0.220
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.218
BAG3	BCL2-associated athanogene 3	0.215
DCN	decorin	0.215
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.215
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.214
LUM	lumican	0.214
COL14A1	collagen, type XIV, alpha 1	0.213
KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.213
CRYGC	crystallin, gamma C	0.212
AR	androgen receptor	0.210
PPIC	peptidylprolyl isomerase C (cyclophilin C)	0.210	Human
CALR	calreticulin	0.210	Human
PLN	phospholamban	0.207
CD84	CD84 molecule	0.207	Human
MYF6	myogenic factor 6 (herculin)	0.206
PRKAA1	protein kinase, AMP-activated, alpha 1 catalytic subunit	0.205
DTNB	dystrobrevin, beta	0.204
C19orf10	chromosome 19 open reading frame 10	0.202
ALB	albumin	0.202
SRI	sorcin	0.201
GAS1	growth arrest-specific 1	0.201
HLA-E	major histocompatibility complex, class I, E	0.200
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.198
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.197
LTBP1	latent transforming growth factor beta binding protein 1	0.197
RYR1	ryanodine receptor 1 (skeletal)	0.196
HNRNPD	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)	0.196	Human
THBS2	thrombospondin 2	0.193	Human
HSPA1B	heat shock 70kDa protein 1B	0.189
MYOM2	myomesin (M-protein) 2, 165kDa	0.189
RSL1D1	ribosomal L1 domain containing 1	0.188
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.188
ADAM15	ADAM metallopeptidase domain 15	0.188
ECM1	extracellular matrix protein 1	0.187
TRAPPC2	trafficking protein particle complex 2	0.185
SYNPO2	synaptopodin 2	0.183
NOSTRIN	nitric oxide synthase trafficker	0.182
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.182
TRAPPC8	trafficking protein particle complex 8	0.181
KBTBD10	kelch repeat and BTB (POZ) domain containing 10	0.181
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.181
ITGA7	integrin, alpha 7	0.180
FXYD1	FXYD domain containing ion transport regulator 1	0.179
FBLIM1	filamin binding LIM protein 1	0.177
DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	0.177
PDIA5	protein disulfide isomerase family A, member 5	0.177
LBX1	ladybird homeobox 1	0.176
GFM1	G elongation factor, mitochondrial 1	0.176
SQSTM1	sequestosome 1	0.176
DBN1	drebrin 1	0.175
IGFBP3	insulin-like growth factor binding protein 3	0.174
PRKCDBP	protein kinase C, delta binding protein	0.174
PLXND1	plexin D1	0.174
CD151	CD151 molecule (Raph blood group)	0.172
THBS1	thrombospondin 1	0.172	Human
NID1	nidogen 1	0.171
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.171
PHKG1	phosphorylase kinase, gamma 1 (muscle)	0.171
COPZ2	coatomer protein complex, subunit zeta 2	0.171
REPS2	RALBP1 associated Eps domain containing 2	0.171
TJP2	tight junction protein 2 (zona occludens 2)	0.171
TRAM2	translocation associated membrane protein 2	0.170
WDYHV1	WDYHV motif containing 1	0.170
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.169
MB	myoglobin	0.167
MYLK2	myosin light chain kinase 2	0.166
LAT	linker for activation of T cells	0.165
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.164
PEX1	peroxisomal biogenesis factor 1	0.164
ATP1A2	ATPase, Na+/K+ transporting, alpha 2 polypeptide	0.164
C20orf94	chromosome 20 open reading frame 94	0.164
HNRNPA3	heterogeneous nuclear ribonucleoprotein A3	0.163
SLC2A4	solute carrier family 2 (facilitated glucose transporter), member 4	0.163
ATXN3	ataxin 3	0.163
MAG	myelin associated glycoprotein	0.163
NRP1	neuropilin 1	0.162
CACNB1	calcium channel, voltage-dependent, beta 1 subunit	0.162
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.162
FGFR1	fibroblast growth factor receptor 1	0.162
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.161
S100A1	S100 calcium binding protein A1	0.160
C16orf59	chromosome 16 open reading frame 59	0.160
NOG	noggin	0.158
CSTF2T	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant	0.158
TGFBR3	transforming growth factor, beta receptor III	0.157
LMOD1	leiomodin 1 (smooth muscle)	0.156
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.154
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.154
ECE1	endothelin converting enzyme 1	0.153	Human
CAPRIN2	caprin family member 2	0.153
SLC35A5	solute carrier family 35, member A5	0.151
MYPN	myopalladin	0.151
PRSS23	protease, serine, 23	0.151
FGFR3	fibroblast growth factor receptor 3	0.151
FGF7	fibroblast growth factor 7	0.151
RHEB	Ras homolog enriched in brain	0.150
TNC	tenascin C	0.150	Human
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.150
C2orf18	chromosome 2 open reading frame 18	0.149
AKAP10	A kinase (PRKA) anchor protein 10	0.149
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.149
ENO3	enolase 3 (beta, muscle)	0.148
MYOZ3	myozenin 3	0.148	Human
GLT25D1	glycosyltransferase 25 domain containing 1	0.147	Human
ALPK3	alpha-kinase 3	0.147
TAPBPL	TAP binding protein-like	0.146
EMP3	epithelial membrane protein 3	0.144
PEBP4	phosphatidylethanolamine-binding protein 4	0.144
ITGB5	integrin, beta 5	0.143
FZD7	frizzled homolog 7 (Drosophila)	0.142
SMN1	survival of motor neuron 1, telomeric	0.142
TMEM214	transmembrane protein 214	0.142
ACTN1	actinin, alpha 1	0.142
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.142
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.141
MVP	major vault protein	0.141
TMEM168	transmembrane protein 168	0.140
ZMYND11	zinc finger, MYND-type containing 11	0.140
CKMT2	creatine kinase, mitochondrial 2 (sarcomeric)	0.140
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.140
CACNG1	calcium channel, voltage-dependent, gamma subunit 1	0.139
TYK2	tyrosine kinase 2	0.139
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.139
FHOD3	formin homology 2 domain containing 3	0.138
THBS4	thrombospondin 4	0.138	Human
NDUFV1	NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa	0.138
NCAM1	neural cell adhesion molecule 1	0.138
CALD1	caldesmon 1	0.137
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.137
UCP3	uncoupling protein 3 (mitochondrial, proton carrier)	0.137
FRS2	fibroblast growth factor receptor substrate 2	0.137
ATN1	atrophin 1	0.136
NRAP	nebulin-related anchoring protein	0.135	Human
PRNP	prion protein	0.135
MYOG	myogenin (myogenic factor 4)	0.134	Human
HSF1	heat shock transcription factor 1	0.134
SLAMF1	signaling lymphocytic activation molecule family member 1	0.134	Human
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.133
GREM1	gremlin 1	0.133
SFRP2	secreted frizzled-related protein 2	0.133
PKP3	plakophilin 3	0.132	Human
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.132
ACTB	actin, beta	0.132	Human
KIAA1377	KIAA1377	0.132
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.132
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.131
CMYA5	cardiomyopathy associated 5	0.130
COL16A1	collagen, type XVI, alpha 1	0.130	Human
NXF1	nuclear RNA export factor 1	0.130
ERBB2IP	erbb2 interacting protein	0.129
PLXNA3	plexin A3	0.129
IGF1	insulin-like growth factor 1 (somatomedin C)	0.129
FGF3	fibroblast growth factor 3	0.127
COL13A1	collagen, type XIII, alpha 1	0.127
SOX11	SRY (sex determining region Y)-box 11	0.126	Human
CD248	CD248 molecule, endosialin	0.126
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.125
STBD1	starch binding domain 1	0.125
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.125
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.125	Human
FNDC1	fibronectin type III domain containing 1	0.125
SPRY2	sprouty homolog 2 (Drosophila)	0.125
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.124
CTTN	cortactin	0.124
CMA1	chymase 1, mast cell	0.124
DOCK7	dedicator of cytokinesis 7	0.124
BMP1	bone morphogenetic protein 1	0.123
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.123
CLCN1	chloride channel 1, skeletal muscle	0.122
WASL	Wiskott-Aldrich syndrome-like	0.122
PLXNA1	plexin A1	0.122
LMCD1	LIM and cysteine-rich domains 1	0.122
CA3	carbonic anhydrase III, muscle specific	0.122	Human
CTHRC1	collagen triple helix repeat containing 1	0.121
CTNND1	catenin (cadherin-associated protein), delta 1	0.121	Human
MYLK	myosin light chain kinase	0.121
TAGLN	transgelin	0.121
TBX1	T-box 1	0.120
TRAF5	TNF receptor-associated factor 5	0.120
E2F2	E2F transcription factor 2	0.119
FERMT2	fermitin family member 2	0.119
GANAB	glucosidase, alpha; neutral AB	0.118
HTRA3	HtrA serine peptidase 3	0.118
LRRC17	leucine rich repeat containing 17	0.118
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.118
SNTB1	syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)	0.118
MYH3	myosin, heavy chain 3, skeletal muscle, embryonic	0.117
PKD1	polycystic kidney disease 1 (autosomal dominant)	0.117
ITGB1BP3	integrin beta 1 binding protein 3	0.117
THY1	Thy-1 cell surface antigen	0.116
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.116
MUSTN1	musculoskeletal, embryonic nuclear protein 1	0.116
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.115
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.115
PLXDC1	plexin domain containing 1	0.115
SORBS1	sorbin and SH3 domain containing 1	0.114
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.114
LMOD2	leiomodin 2 (cardiac)	0.114
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.113
NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)	0.113
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.113
AANAT	aralkylamine N-acetyltransferase	0.113
CKAP4	cytoskeleton-associated protein 4	0.112
FOXF2	forkhead box F2	0.112
HOXB1	homeobox B1	0.112
HIST2H3C	histone cluster 2, H3c	0.112
PGM5	phosphoglucomutase 5	0.111
RCN1	reticulocalbin 1, EF-hand calcium binding domain	0.111
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.111
DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	0.110
APC	adenomatous polyposis coli	0.110
CUX1	cut-like homeobox 1	0.110
PTK7	PTK7 protein tyrosine kinase 7	0.110
NGF	nerve growth factor (beta polypeptide)	0.110
CHTF18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.109
FGF6	fibroblast growth factor 6	0.109
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.108
CRLF1	cytokine receptor-like factor 1	0.108
GLI2	GLI family zinc finger 2	0.107	Human
GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)	0.107
E2F1	E2F transcription factor 1	0.107
PDGFA	platelet-derived growth factor alpha polypeptide	0.107
KRIT1	KRIT1, ankyrin repeat containing	0.106
NCL	nucleolin	0.106
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.106
SH3BP2	SH3-domain binding protein 2	0.106
HSPA1A	heat shock 70kDa protein 1A	0.106
FKBP2	FK506 binding protein 2, 13kDa	0.105
MFGE8	milk fat globule-EGF factor 8 protein	0.105
MXRA8	matrix-remodelling associated 8	0.105
FBXO40	F-box protein 40	0.105
ZCCHC24	zinc finger, CCHC domain containing 24	0.104
MSC	musculin	0.104
PALLD	palladin, cytoskeletal associated protein	0.104	Human
MLEC	malectin	0.104
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.104
DISC1	disrupted in schizophrenia 1	0.104
PDE9A	phosphodiesterase 9A	0.103	Human
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.103
PRRX2	paired related homeobox 2	0.103
S100A10	S100 calcium binding protein A10	0.103
LAMA4	laminin, alpha 4	0.103
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.102
SUFU	suppressor of fused homolog (Drosophila)	0.101
TWIST2	twist homolog 2 (Drosophila)	0.101
DMPK	dystrophia myotonica-protein kinase	0.101
TUBB6	tubulin, beta 6	0.101
SLIT3	slit homolog 3 (Drosophila)	0.100
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.100
DPT	dermatopontin	0.100
AMPD1	adenosine monophosphate deaminase 1	0.099
GPX8	glutathione peroxidase 8 (putative)	0.099
DLX5	distal-less homeobox 5	0.099
VGLL2	vestigial like 2 (Drosophila)	0.098
NELL2	NEL-like 2 (chicken)	0.098
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.097	Human
DIO2	deiodinase, iodothyronine, type II	0.097
CCL7	chemokine (C-C motif) ligand 7	0.097
INHBA	inhibin, beta A	0.097
NID2	nidogen 2 (osteonidogen)	0.096
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.096
SACM1L	SAC1 suppressor of actin mutations 1-like (yeast)	0.096
EMD	emerin	0.096
GABARAPL1	GABA(A) receptor-associated protein like 1	0.095
C10orf71	chromosome 10 open reading frame 71	0.095
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.095
LAMA5	laminin, alpha 5	0.095	Human
BAG2	BCL2-associated athanogene 2	0.095
ATF1	activating transcription factor 1	0.095
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.094
CCDC80	coiled-coil domain containing 80	0.094
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.094
RHOD	ras homolog gene family, member D	0.094
COX7A1	cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)	0.094
TRAF6	TNF receptor-associated factor 6	0.093
STK36	serine/threonine kinase 36	0.093
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.093
TRDN	triadin	0.092
PPP1R1A	protein phosphatase 1, regulatory (inhibitor) subunit 1A	0.092
TMED9	transmembrane emp24 protein transport domain containing 9	0.092
MAX	MYC associated factor X	0.092
CHPF	chondroitin polymerizing factor	0.092
NPTN	neuroplastin	0.092
BID	BH3 interacting domain death agonist	0.091
IRAK2	interleukin-1 receptor-associated kinase 2	0.091
COL10A1	collagen, type X, alpha 1	0.091
SMTNL1	smoothelin-like 1	0.091
LAMA2	laminin, alpha 2	0.091
COL4A4	collagen, type IV, alpha 4	0.091
KRT14	keratin 14	0.090
MSX2	msh homeobox 2	0.090
FAM189A2	family with sequence similarity 189, member A2	0.090
LOXL2	lysyl oxidase-like 2	0.090
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.090
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.089
CRYBB1	crystallin, beta B1	0.089
NCOA6	nuclear receptor coactivator 6	0.089
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.089
CRYBA1	crystallin, beta A1	0.089
SCN5A	sodium channel, voltage-gated, type V, alpha subunit	0.088
MEF2C	myocyte enhancer factor 2C	0.088
WDR62	WD repeat domain 62	0.088
COL12A1	collagen, type XII, alpha 1	0.088
KLF5	Kruppel-like factor 5 (intestinal)	0.088
BMP8A	bone morphogenetic protein 8a	0.088	Human
EXTL1	exostoses (multiple)-like 1	0.088
RAD54L	RAD54-like (S. cerevisiae)	0.087
NAP1L1	nucleosome assembly protein 1-like 1	0.087
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.087
PECAM1	platelet/endothelial cell adhesion molecule	0.087
FGF8	fibroblast growth factor 8 (androgen-induced)	0.087
HSPB6	heat shock protein, alpha-crystallin-related, B6	0.087	Human
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.087
NCOR2	nuclear receptor corepressor 2	0.086
RRAD	Ras-related associated with diabetes	0.086
ATXN1	ataxin 1	0.086
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.086
LRRC15	leucine rich repeat containing 15	0.085
STAT2	signal transducer and activator of transcription 2, 113kDa	0.085
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.085	Human
BMP4	bone morphogenetic protein 4	0.085	Human
SPTB	spectrin, beta, erythrocytic	0.085
HK2	hexokinase 2	0.085
TWIST1	twist homolog 1 (Drosophila)	0.084
ADAM19	ADAM metallopeptidase domain 19	0.084
MED25	mediator complex subunit 25	0.084
CORO6	coronin 6	0.084
TPBG	trophoblast glycoprotein	0.084
ESR1	estrogen receptor 1	0.084
HOXA11	homeobox A11	0.084
SSR4	signal sequence receptor, delta (translocon-associated protein delta)	0.084
PTMA	prothymosin, alpha	0.083
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.083
TMEM128	transmembrane protein 128	0.083
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.083
ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	0.083
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.083
XIRP2	xin actin-binding repeat containing 2	0.083
IREB2	iron-responsive element binding protein 2	0.083
RNF14	ring finger protein 14	0.083
NFIC	nuclear factor I/C (CCAAT-binding transcription factor)	0.082
MBTPS1	membrane-bound transcription factor peptidase, site 1	0.082
CD274	CD274 molecule	0.082
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.082
UNC5B	unc-5 homolog B (C. elegans)	0.081
HYOU1	hypoxia up-regulated 1	0.081
SIX2	SIX homeobox 2	0.081
TBX5	T-box 5	0.081
SPEG	SPEG complex locus	0.081
FOXD1	forkhead box D1	0.081
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.081	Human
METTL17	methyltransferase like 17	0.080
PDGFRL	platelet-derived growth factor receptor-like	0.080
CALML6	calmodulin-like 6	0.080
CIB1	calcium and integrin binding 1 (calmyrin)	0.080
PPP1R3A	protein phosphatase 1, regulatory (inhibitor) subunit 3A	0.080
TMEM47	transmembrane protein 47	0.080
DHRS7C	dehydrogenase/reductase (SDR family) member 7C	0.080
CRABP2	cellular retinoic acid binding protein 2	0.080
SDF2L1	stromal cell-derived factor 2-like 1	0.080
SMAD6	SMAD family member 6	0.080
SDC4	syndecan 4	0.080
S100A3	S100 calcium binding protein A3	0.079
AHNAK	AHNAK nucleoprotein	0.079
MYO1E	myosin IE	0.079
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.079
ANKRD23	ankyrin repeat domain 23	0.079
VMP1	vacuole membrane protein 1	0.079
MYO1C	myosin IC	0.079
GJA5	gap junction protein, alpha 5, 40kDa	0.078
PPFIA4	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4	0.078
MYBPC3	myosin binding protein C, cardiac	0.078
DDN	dendrin	0.078
SRSF6	serine/arginine-rich splicing factor 6	0.078
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.078
PKD2L1	polycystic kidney disease 2-like 1	0.078
TRIM54	tripartite motif containing 54	0.078
PPP5C	protein phosphatase 5, catalytic subunit	0.078
METRN	meteorin, glial cell differentiation regulator	0.078
ISG15	ISG15 ubiquitin-like modifier	0.078
HOXD9	homeobox D9	0.078
SRL	sarcalumenin	0.078
OCLN	occludin	0.077
SLC38A6	solute carrier family 38, member 6	0.077
GNS	glucosamine (N-acetyl)-6-sulfatase	0.077
CXCR5	chemokine (C-X-C motif) receptor 5	0.077
SUCLG1	succinate-CoA ligase, alpha subunit	0.077
GPC4	glypican 4	0.077
PDCD7	programmed cell death 7	0.077
C11orf24	chromosome 11 open reading frame 24	0.077
COPG	coatomer protein complex, subunit gamma	0.077
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.076
EZR	ezrin	0.076
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.076
MRAS	muscle RAS oncogene homolog	0.076
PHKB	phosphorylase kinase, beta	0.075
DTX2	deltex homolog 2 (Drosophila)	0.075
SYNE2	spectrin repeat containing, nuclear envelope 2	0.075
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.075
NGFR	nerve growth factor receptor	0.075
ERO1L	ERO1-like (S. cerevisiae)	0.075
CD276	CD276 molecule	0.074
GLI3	GLI family zinc finger 3	0.074
ZYX	zyxin	0.074
EPAS1	endothelial PAS domain protein 1	0.074
TRIM55	tripartite motif containing 55	0.074
COL4A5	collagen, type IV, alpha 5	0.074
MYL7	myosin, light chain 7, regulatory	0.074	Human
HAS2	hyaluronan synthase 2	0.074
TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.074
SLCO5A1	solute carrier organic anion transporter family, member 5A1	0.074
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.073
PERP	PERP, TP53 apoptosis effector	0.073
SAMM50	sorting and assembly machinery component 50 homolog (S. cerevisiae)	0.073
CD99	CD99 molecule	0.073
C6orf120	chromosome 6 open reading frame 120	0.073
PCDH7	protocadherin 7	0.073
SFRP1	secreted frizzled-related protein 1	0.073
HOXB13	homeobox B13	0.073	Human
FABP3	fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)	0.073
MAPK8	mitogen-activated protein kinase 8	0.073
HYAL4	hyaluronoglucosaminidase 4	0.073
ACAN	aggrecan	0.073
FBXW8	F-box and WD repeat domain containing 8	0.072
SYNE1	spectrin repeat containing, nuclear envelope 1	0.072
PHLDB2	pleckstrin homology-like domain, family B, member 2	0.072
PITX2	paired-like homeodomain 2	0.072	Human
CALCA	calcitonin-related polypeptide alpha	0.072
SRSF5	serine/arginine-rich splicing factor 5	0.072
MYO18B	myosin XVIIIB	0.072
FMO1	flavin containing monooxygenase 1	0.072
EPS15	epidermal growth factor receptor pathway substrate 15	0.072
TP63	tumor protein p63	0.072
MSLN	mesothelin	0.072
NTM	neurotrimin	0.072
NBL1	neuroblastoma, suppression of tumorigenicity 1	0.072
COL15A1	collagen, type XV, alpha 1	0.071
TNXB	tenascin XB	0.071
HFE2	hemochromatosis type 2 (juvenile)	0.071
OLFML2B	olfactomedin-like 2B	0.071
FZD8	frizzled homolog 8 (Drosophila)	0.071
SOX6	SRY (sex determining region Y)-box 6	0.071
ARTN	artemin	0.071
B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	0.071
FGF18	fibroblast growth factor 18	0.071
IL2RA	interleukin 2 receptor, alpha	0.071
ANTXR1	anthrax toxin receptor 1	0.071
TMEM52	transmembrane protein 52	0.071
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.071