IMP: Integrative Multi-species Prediction

Homo sapiens

109 genes annotated in human

connective tissue disease

DOID:65

A tissue disease that affects tissues such as skin, tendons, and cartilage.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "connective tissue disease"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "connective tissue disease" (in gray)

Name	Description	Probability	Func Analog Organism
BMPR1A	bone morphogenetic protein receptor, type IA	1.000	Human
COL1A1	collagen, type I, alpha 1	0.998
FGF1	fibroblast growth factor 1 (acidic)	0.997
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.992
COL1A2	collagen, type I, alpha 2	0.986
COL5A1	collagen, type V, alpha 1	0.983
TJP1	tight junction protein 1 (zona occludens 1)	0.966
HLA-DMB	major histocompatibility complex, class II, DM beta	0.964
COL3A1	collagen, type III, alpha 1	0.942
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.917
FGFR2	fibroblast growth factor receptor 2	0.892
COL4A1	collagen, type IV, alpha 1	0.882
COL6A1	collagen, type VI, alpha 1	0.873
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.867
PDIA3	protein disulfide isomerase family A, member 3	0.865
LOX	lysyl oxidase	0.846
CHRD	chordin	0.834
FSTL1	follistatin-like 1	0.830
COL6A2	collagen, type VI, alpha 2	0.829
BMP2	bone morphogenetic protein 2	0.818
PDIA4	protein disulfide isomerase family A, member 4	0.811
FLNA	filamin A, alpha	0.807	Human
BMPR1B	bone morphogenetic protein receptor, type IB	0.795
SMAD1	SMAD family member 1	0.782
DDR2	discoidin domain receptor tyrosine kinase 2	0.766
CD247	CD247 molecule	0.718
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.695
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.692
FGF10	fibroblast growth factor 10	0.691
IL10RA	interleukin 10 receptor, alpha	0.690
PSEN1	presenilin 1	0.688
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.656
GDF5	growth differentiation factor 5	0.655
CD80	CD80 molecule	0.647
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.639	Human
COL4A2	collagen, type IV, alpha 2	0.628
COL5A2	collagen, type V, alpha 2	0.620
RXRA	retinoid X receptor, alpha	0.598
LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	0.595
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.580
COL2A1	collagen, type II, alpha 1	0.554
SETD8	SET domain containing (lysine methyltransferase) 8	0.550
FGF2	fibroblast growth factor 2 (basic)	0.547
BGN	biglycan	0.523
RBPMS	RNA binding protein with multiple splicing	0.522
PCOLCE	procollagen C-endopeptidase enhancer	0.506
CD86	CD86 molecule	0.501
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.490	Human
KRT8	keratin 8	0.486
PXDN	peroxidasin homolog (Drosophila)	0.481
HR	hairless homolog (mouse)	0.469
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.463
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.452
SKIL	SKI-like oncogene	0.446	Human
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.442
COL11A1	collagen, type XI, alpha 1	0.439	Human
BMP7	bone morphogenetic protein 7	0.414	Human
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.388
ENG	endoglin	0.382
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.372	Human
TROAP	trophinin associated protein (tastin)	0.366
RPN1	ribophorin I	0.354
SMAD3	SMAD family member 3	0.350
BBS10	Bardet-Biedl syndrome 10	0.347
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.343
NBR1	neighbor of BRCA1 gene 1	0.342
FN1	fibronectin 1	0.341	Human
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.340
CRELD2	cysteine-rich with EGF-like domains 2	0.338
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.330
MRC2	mannose receptor, C type 2	0.324
SH2D1A	SH2 domain containing 1A	0.324
RARA	retinoic acid receptor, alpha	0.323
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.297
COL8A2	collagen, type VIII, alpha 2	0.294	Human
POSTN	periostin, osteoblast specific factor	0.292
CLEC18C	C-type lectin domain family 18, member C	0.286
TGFBR1	transforming growth factor, beta receptor 1	0.280	Human
RUNX1	runt-related transcription factor 1	0.272	Human
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.270
MFAP2	microfibrillar-associated protein 2	0.268
CNTF	ciliary neurotrophic factor	0.265
SMAD4	SMAD family member 4	0.263
PSEN2	presenilin 2 (Alzheimer disease 4)	0.260
C1orf93	chromosome 1 open reading frame 93	0.244
MSX1	msh homeobox 1	0.243	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.235	Human
LOXL1	lysyl oxidase-like 1	0.225
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.221
HSPG2	heparan sulfate proteoglycan 2	0.217
FKBP10	FK506 binding protein 10, 65 kDa	0.212
CALR	calreticulin	0.210
CD84	CD84 molecule	0.207	Human
C19orf10	chromosome 19 open reading frame 10	0.202
FBLN2	fibulin 2	0.200
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.197
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.196
NOSTRIN	nitric oxide synthase trafficker	0.182
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.182
COL7A1	collagen, type VII, alpha 1	0.181
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.181
FBLIM1	filamin binding LIM protein 1	0.177
PDIA5	protein disulfide isomerase family A, member 5	0.177
IGFBP3	insulin-like growth factor binding protein 3	0.174
THBS1	thrombospondin 1	0.172	Human
NID1	nidogen 1	0.171
LAT	linker for activation of T cells	0.165
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.162
FGFR1	fibroblast growth factor receptor 1	0.162
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.161
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.161
C16orf59	chromosome 16 open reading frame 59	0.160
NOG	noggin	0.158
SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	0.157
PPIC	peptidylprolyl isomerase C (cyclophilin C)	0.155	Human
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.154
THBS2	thrombospondin 2	0.154	Human
FGFR3	fibroblast growth factor receptor 3	0.151
FGF7	fibroblast growth factor 7	0.151
TNC	tenascin C	0.150	Human
C2orf18	chromosome 2 open reading frame 18	0.149
AKAP10	A kinase (PRKA) anchor protein 10	0.149
MXRA5	matrix-remodelling associated 5	0.149
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.148
GLT25D1	glycosyltransferase 25 domain containing 1	0.147	Human
EMP3	epithelial membrane protein 3	0.144
NRP1	neuropilin 1	0.144
CAPRIN2	caprin family member 2	0.140
COL18A1	collagen, type XVIII, alpha 1	0.137
FRS2	fibroblast growth factor receptor substrate 2	0.137
EMILIN1	elastin microfibril interfacer 1	0.133
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.133
KIAA1377	KIAA1377	0.132
LMF2	lipase maturation factor 2	0.128
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.126
ADAM12	ADAM metallopeptidase domain 12	0.126
STBD1	starch binding domain 1	0.125
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.125
PKP4	plakophilin 4	0.125
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.124
BMP1	bone morphogenetic protein 1	0.123
COL6A3	collagen, type VI, alpha 3	0.123
WISP1	WNT1 inducible signaling pathway protein 1	0.120
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.120
E2F2	E2F transcription factor 2	0.119
GANAB	glucosidase, alpha; neutral AB	0.118
CSPG4	chondroitin sulfate proteoglycan 4	0.118
PLXND1	plexin D1	0.117
FBN1	fibrillin 1	0.116
THY1	Thy-1 cell surface antigen	0.113
LAMB1	laminin, beta 1	0.111
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.109
E2F1	E2F transcription factor 1	0.107
HLA-A	major histocompatibility complex, class I, A	0.107
PDGFA	platelet-derived growth factor alpha polypeptide	0.107
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.106
SH3BP2	SH3-domain binding protein 2	0.106
KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.102
AEBP1	AE binding protein 1	0.101
SUFU	suppressor of fused homolog (Drosophila)	0.101
RHOXF2	Rhox homeobox family, member 2	0.101
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.100
LEPREL4	leprecan-like 4	0.099
DLX5	distal-less homeobox 5	0.099
CKAP4	cytoskeleton-associated protein 4	0.098
NELL2	NEL-like 2 (chicken)	0.098
FNDC1	fibronectin type III domain containing 1	0.097
INHBA	inhibin, beta A	0.097
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.097
COL16A1	collagen, type XVI, alpha 1	0.096	Human
NID2	nidogen 2 (osteonidogen)	0.096
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.095
GABARAPL1	GABA(A) receptor-associated protein like 1	0.094
STK36	serine/threonine kinase 36	0.093
RCN1	reticulocalbin 1, EF-hand calcium binding domain	0.092
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.092	Human
FKBP2	FK506 binding protein 2, 13kDa	0.092
TRAM2	translocation associated membrane protein 2	0.092
NPTN	neuroplastin	0.092
BID	BH3 interacting domain death agonist	0.090
MS4A1	membrane-spanning 4-domains, subfamily A, member 1	0.090
NCOA6	nuclear receptor coactivator 6	0.089
TGFB3	transforming growth factor, beta 3	0.088
COMP	cartilage oligomeric matrix protein	0.087
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.087
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.087
ZFYVE9	zinc finger, FYVE domain containing 9	0.086
NCOR2	nuclear receptor corepressor 2	0.086
STAT2	signal transducer and activator of transcription 2, 113kDa	0.085
MED25	mediator complex subunit 25	0.084
COL5A3	collagen, type V, alpha 3	0.084	Human
SSR4	signal sequence receptor, delta (translocon-associated protein delta)	0.084
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.083
ZMYND11	zinc finger, MYND-type containing 11	0.083
CD274	CD274 molecule	0.082
UNC5B	unc-5 homolog B (C. elegans)	0.081
HYOU1	hypoxia up-regulated 1	0.081
MSX2	msh homeobox 2	0.078
GNS	glucosamine (N-acetyl)-6-sulfatase	0.077
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.077
TMED9	transmembrane emp24 protein transport domain containing 9	0.077
COPG	coatomer protein complex, subunit gamma	0.077
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.076
GLI2	GLI family zinc finger 2	0.076	Human
HLA-C	major histocompatibility complex, class I, C	0.076
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.076
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.076
TRAF5	TNF receptor-associated factor 5	0.075
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.075
ERO1L	ERO1-like (S. cerevisiae)	0.075
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.075
EPAS1	endothelial PAS domain protein 1	0.074
CHTF18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.074
ACAN	aggrecan	0.073
PDE4DIP	phosphodiesterase 4D interacting protein	0.071
ITGB4	integrin, beta 4	0.071
GMPPA	GDP-mannose pyrophosphorylase A	0.070
FKBP9	FK506 binding protein 9, 63 kDa	0.070
ITGB5	integrin, beta 5	0.068
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.068
FZD7	frizzled homolog 7 (Drosophila)	0.067
LMO4	LIM domain only 4	0.067
BMP4	bone morphogenetic protein 4	0.067	Human
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.067
BCL2L1	BCL2-like 1	0.066
CCL7	chemokine (C-C motif) ligand 7	0.066
GPR161	G protein-coupled receptor 161	0.065
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.065
MAPK8	mitogen-activated protein kinase 8	0.064
SSR2	signal sequence receptor, beta (translocon-associated protein beta)	0.064
LEPREL2	leprecan-like 2	0.064	Human
FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)	0.064
FAM64A	family with sequence similarity 64, member A	0.064
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.064	Human
HOXA9	homeobox A9	0.063
CD33	CD33 molecule	0.063
MXRA8	matrix-remodelling associated 8	0.062
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.062
HAP1	huntingtin-associated protein 1	0.062
FOXF2	forkhead box F2	0.062
ECE1	endothelin converting enzyme 1	0.062
PTHLH	parathyroid hormone-like hormone	0.061
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.061
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.061	Human
CDK6	cyclin-dependent kinase 6	0.061
CLEC4M	C-type lectin domain family 4, member M	0.061
LUM	lumican	0.061
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.061	Human
TGFB2	transforming growth factor, beta 2	0.061	Human
SOAT1	sterol O-acyltransferase 1	0.061
ECM1	extracellular matrix protein 1	0.061
LCK	lymphocyte-specific protein tyrosine kinase	0.060
RBM11	RNA binding motif protein 11	0.059
P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	0.059
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.059
STC1	stanniocalcin 1	0.058
RADIL	Ras association and DIL domains	0.058
SMAD2	SMAD family member 2	0.058
BMP8A	bone morphogenetic protein 8a	0.058	Human
TWIST1	twist homolog 1 (Drosophila)	0.058
GLG1	golgi glycoprotein 1	0.058
EXT1	exostosin 1	0.057
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.057
TMED3	transmembrane emp24 protein transport domain containing 3	0.057
SMAD7	SMAD family member 7	0.057
TSPAN4	tetraspanin 4	0.057
PDGFRL	platelet-derived growth factor receptor-like	0.057
EXT2	exostosin 2	0.057
SFRP2	secreted frizzled-related protein 2	0.056
SOX11	SRY (sex determining region Y)-box 11	0.056	Human
OCLN	occludin	0.056
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.056
PDIA6	protein disulfide isomerase family A, member 6	0.056
FOXD1	forkhead box D1	0.055
LBX1	ladybird homeobox 1	0.055
ACTN4	actinin, alpha 4	0.055
GPC1	glypican 1	0.055
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.054
LGALS1	lectin, galactoside-binding, soluble, 1	0.054
B2M	beta-2-microglobulin	0.054
PRSS23	protease, serine, 23	0.054
BAG3	BCL2-associated athanogene 3	0.054
IGFBP4	insulin-like growth factor binding protein 4	0.054
MBTPS1	membrane-bound transcription factor peptidase, site 1	0.054
DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)	0.054
C10orf54	chromosome 10 open reading frame 54	0.054
COL12A1	collagen, type XII, alpha 1	0.054
CTHRC1	collagen triple helix repeat containing 1	0.053
ELN	elastin	0.053
PRKCDBP	protein kinase C, delta binding protein	0.053
MSN	moesin	0.053
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.053
VMP1	vacuole membrane protein 1	0.053
PTK7	PTK7 protein tyrosine kinase 7	0.053
IFNGR1	interferon gamma receptor 1	0.053
NCSTN	nicastrin	0.052
WWTR1	WW domain containing transcription regulator 1	0.052
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.052
RUNX2	runt-related transcription factor 2	0.052
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.052
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.052
SPHK1	sphingosine kinase 1	0.052
IFT88	intraflagellar transport 88 homolog (Chlamydomonas)	0.052
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.052
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.051
MFSD1	major facilitator superfamily domain containing 1	0.051
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.051
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.051
HOXA11	homeobox A11	0.051
HYAL1	hyaluronoglucosaminidase 1	0.051
USP42	ubiquitin specific peptidase 42	0.051
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.051
RANBP9	RAN binding protein 9	0.051
SDF2L1	stromal cell-derived factor 2-like 1	0.051
WNT5A	wingless-type MMTV integration site family, member 5A	0.051	Human
ANTXR2	anthrax toxin receptor 2	0.050
CD28	CD28 molecule	0.050	Human
PRRX2	paired related homeobox 2	0.050
HSPB8	heat shock 22kDa protein 8	0.050
COL10A1	collagen, type X, alpha 1	0.050
LAMB2	laminin, beta 2 (laminin S)	0.050
ANGPTL2	angiopoietin-like 2	0.050
EDEM2	ER degradation enhancer, mannosidase alpha-like 2	0.050
SND1	staphylococcal nuclease and tudor domain containing 1	0.049
PLTP	phospholipid transfer protein	0.049
FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	0.049
TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.049
DOCK9	dedicator of cytokinesis 9	0.049
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.049
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.049
HAS2	hyaluronan synthase 2	0.049
EHD2	EH-domain containing 2	0.048
LOXL2	lysyl oxidase-like 2	0.048
FAM46D	family with sequence similarity 46, member D	0.048
IRF9	interferon regulatory factor 9	0.048	Human
COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	0.048
CRABP2	cellular retinoic acid binding protein 2	0.048
TAL1	T-cell acute lymphocytic leukemia 1	0.048	Human
C5orf22	chromosome 5 open reading frame 22	0.048
RPN2	ribophorin II	0.048
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.048
UBA7	ubiquitin-like modifier activating enzyme 7	0.048
GLI3	GLI family zinc finger 3	0.048
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.047
GLT8D2	glycosyltransferase 8 domain containing 2	0.047
PAQR4	progestin and adipoQ receptor family member IV	0.047
COL9A3	collagen, type IX, alpha 3	0.047	Human
TYK2	tyrosine kinase 2	0.047
EPHB3	EPH receptor B3	0.047
SLC38A7	solute carrier family 38, member 7	0.047
SIL1	SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)	0.047
EFR3A	EFR3 homolog A (S. cerevisiae)	0.047
OPTN	optineurin	0.047
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.047
TPBG	trophoblast glycoprotein	0.047
SFRP4	secreted frizzled-related protein 4	0.047
WT1	Wilms tumor 1	0.047
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.046
WNT2	wingless-type MMTV integration site family member 2	0.046	Human
LIG4	ligase IV, DNA, ATP-dependent	0.046
COL4A5	collagen, type IV, alpha 5	0.046
C9orf140	chromosome 9 open reading frame 140	0.046
CRLF1	cytokine receptor-like factor 1	0.046
GJD3	gap junction protein, delta 3, 31.9kDa	0.046
RNF31	ring finger protein 31	0.046
LRRC15	leucine rich repeat containing 15	0.046
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.046
C3orf64	chromosome 3 open reading frame 64	0.045
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.045
MAG	myelin associated glycoprotein	0.045
EDNRA	endothelin receptor type A	0.045
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.045
CALU	calumenin	0.044
LY9	lymphocyte antigen 9	0.044	Human
TAPBPL	TAP binding protein-like	0.044
MAN1B1	mannosidase, alpha, class 1B, member 1	0.044
TJP2	tight junction protein 2 (zona occludens 2)	0.044
HMGA2	high mobility group AT-hook 2	0.044
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.044
FZD8	frizzled homolog 8 (Drosophila)	0.043
ERO1LB	ERO1-like beta (S. cerevisiae)	0.043
DLX4	distal-less homeobox 4	0.043
NTM	neurotrimin	0.043
FAP	fibroblast activation protein, alpha	0.043
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.043
MCAM	melanoma cell adhesion molecule	0.043
TELO2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.043
COL14A1	collagen, type XIV, alpha 1	0.042
LRRC17	leucine rich repeat containing 17	0.042
CLDN7	claudin 7	0.042
PDLIM4	PDZ and LIM domain 4	0.042
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.042
GDF6	growth differentiation factor 6	0.042	Human
CLASRP	CLK4-associating serine/arginine rich protein	0.042
SRI	sorcin	0.041
GPX8	glutathione peroxidase 8 (putative)	0.041
TWIST2	twist homolog 2 (Drosophila)	0.041
WNT11	wingless-type MMTV integration site family, member 11	0.041	Human
EPHB2	EPH receptor B2	0.041
NKX3-2	NK3 homeobox 2	0.041
ZBED1	zinc finger, BED-type containing 1	0.041
SHB	Src homology 2 domain containing adaptor protein B	0.041
FOXC1	forkhead box C1	0.041
CCL22	chemokine (C-C motif) ligand 22	0.041
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.041
LAMB3	laminin, beta 3	0.041
DTX2	deltex homolog 2 (Drosophila)	0.040
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.040
IRF4	interferon regulatory factor 4	0.040
GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	0.040
PMEPA1	prostate transmembrane protein, androgen induced 1	0.040
IL2RA	interleukin 2 receptor, alpha	0.040
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.040
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.040
NKD2	naked cuticle homolog 2 (Drosophila)	0.040
FEV	FEV (ETS oncogene family)	0.040
C7orf42	chromosome 7 open reading frame 42	0.040
HOXD11	homeobox D11	0.040
ZEB2	zinc finger E-box binding homeobox 2	0.039
CREB3L1	cAMP responsive element binding protein 3-like 1	0.039
VSX1	visual system homeobox 1	0.039
OLFML2B	olfactomedin-like 2B	0.039
KAT2B	K(lysine) acetyltransferase 2B	0.039
PLXNA1	plexin A1	0.039
SHOX2	short stature homeobox 2	0.039
HOXB13	homeobox B13	0.039	Human
EFHC1	EF-hand domain (C-terminal) containing 1	0.039
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.039
C14orf80	chromosome 14 open reading frame 80	0.039
ZNF431	zinc finger protein 431	0.039
FNDC3B	fibronectin type III domain containing 3B	0.039
ATG7	ATG7 autophagy related 7 homolog (S. cerevisiae)	0.039
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.039	Human
MTMR4	myotubularin related protein 4	0.039
ARRDC3	arrestin domain containing 3	0.039
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.039
PGCP	plasma glutamate carboxypeptidase	0.038
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.038
CHPF2	chondroitin polymerizing factor 2	0.038
LAMA5	laminin, alpha 5	0.038
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.038	Human
FHOD3	formin homology 2 domain containing 3	0.038
HOXD9	homeobox D9	0.038
TNR	tenascin R (restrictin, janusin)	0.038	Human
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.038
B3GAT3	beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)	0.037
IL11	interleukin 11	0.037
GAS1	growth arrest-specific 1	0.037
CCDC17	coiled-coil domain containing 17	0.037
CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1	0.037
HEXB	hexosaminidase B (beta polypeptide)	0.037
NCAPH2	non-SMC condensin II complex, subunit H2	0.037
CD248	CD248 molecule, endosialin	0.037
SOCS1	suppressor of cytokine signaling 1	0.037
PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	0.037	Human
FGF3	fibroblast growth factor 3	0.037
TMEM158	transmembrane protein 158 (gene/pseudogene)	0.037
C9orf100	chromosome 9 open reading frame 100	0.037
NEU4	sialidase 4	0.037
CARHSP1	calcium regulated heat stable protein 1, 24kDa	0.037
IDUA	iduronidase, alpha-L-	0.037
BCL2L12	BCL2-like 12 (proline rich)	0.037
MARCH1	membrane-associated ring finger (C3HC4) 1	0.037
HS2ST1	heparan sulfate 2-O-sulfotransferase 1	0.037
PYCR1	pyrroline-5-carboxylate reductase 1	0.036
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.036
ARTN	artemin	0.036
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.036	Human
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.036	Human
THBS3	thrombospondin 3	0.036	Human
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.036
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.036
KAL1	Kallmann syndrome 1 sequence	0.036
ISG15	ISG15 ubiquitin-like modifier	0.036
CD1C	CD1c molecule	0.036
MRGPRF	MAS-related GPR, member F	0.036
RHOD	ras homolog gene family, member D	0.036
SNAI2	snail homolog 2 (Drosophila)	0.036
SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	0.036
VASN	vasorin	0.036
HTRA3	HtrA serine peptidase 3	0.036
SPON2	spondin 2, extracellular matrix protein	0.036
TMEM45A	transmembrane protein 45A	0.036
TGFBR3	transforming growth factor, beta receptor III	0.035
IGFBP5	insulin-like growth factor binding protein 5	0.035
ACVR1	activin A receptor, type I	0.035
FANCA	Fanconi anemia, complementation group A	0.035
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.035
CCHCR1	coiled-coil alpha-helical rod protein 1	0.035
DEDD	death effector domain containing	0.035
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.035
PAX5	paired box 5	0.035
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.035
NAGA	N-acetylgalactosaminidase, alpha-	0.035
ACVR1B	activin A receptor, type IB	0.035	Human
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.035	Human
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.035
GREM1	gremlin 1	0.035
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.035
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.035
SRPX2	sushi-repeat containing protein, X-linked 2	0.035
FST	follistatin	0.035
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.034
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.034
CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	0.034
A1BG	alpha-1-B glycoprotein	0.034
FRZB	frizzled-related protein	0.034
FBXO21	F-box protein 21	0.034
C11orf24	chromosome 11 open reading frame 24	0.034
EN1	engrailed homeobox 1	0.034
SLAMF1	signaling lymphocytic activation molecule family member 1	0.034	Human
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.034
FKBP11	FK506 binding protein 11, 19 kDa	0.034
VAV1	vav 1 guanine nucleotide exchange factor	0.034
LAP3	leucine aminopeptidase 3	0.034
SULF1	sulfatase 1	0.034
SPRY2	sprouty homolog 2 (Drosophila)	0.034
NCOA1	nuclear receptor coactivator 1	0.034
C17orf62	chromosome 17 open reading frame 62	0.034
EYA2	eyes absent homolog 2 (Drosophila)	0.034
C17orf53	chromosome 17 open reading frame 53	0.034
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.034
PRPH	peripherin	0.033
CCND3	cyclin D3	0.033
MFGE8	milk fat globule-EGF factor 8 protein	0.033
POU2F2	POU class 2 homeobox 2	0.033
LMNA	lamin A/C	0.033
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.033
KRT16	keratin 16	0.033
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.033
CA12	carbonic anhydrase XII	0.033
TIMP3	TIMP metallopeptidase inhibitor 3	0.033
ATP10D	ATPase, class V, type 10D	0.033
PILRA	paired immunoglobin-like type 2 receptor alpha	0.033
PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa	0.033
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.033
SOX9	SRY (sex determining region Y)-box 9	0.033
MVP	major vault protein	0.033
ZRANB1	zinc finger, RAN-binding domain containing 1	0.033
PAM	peptidylglycine alpha-amidating monooxygenase	0.033
ING2	inhibitor of growth family, member 2	0.033
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.033
HTRA1	HtrA serine peptidase 1	0.032
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.032
RENBP	renin binding protein	0.032
FGF8	fibroblast growth factor 8 (androgen-induced)	0.032
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.032	Human
HM13	histocompatibility (minor) 13	0.032
USP15	ubiquitin specific peptidase 15	0.032
PRKG1	protein kinase, cGMP-dependent, type I	0.032
NINJ1	ninjurin 1	0.032
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.032	Human
CDK14	cyclin-dependent kinase 14	0.032
BDKRB1	bradykinin receptor B1	0.032
KRT75	keratin 75	0.032
NPTX2	neuronal pentraxin II	0.032
LRP12	low density lipoprotein receptor-related protein 12	0.032
CD276	CD276 molecule	0.032
CCPG1	cell cycle progression 1	0.032
MSC	musculin	0.032
ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)	0.032
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.032
PTDSS2	phosphatidylserine synthase 2	0.032
PDCD1LG2	programmed cell death 1 ligand 2	0.032
AXL	AXL receptor tyrosine kinase	0.032
RARG	retinoic acid receptor, gamma	0.032
ACTN1	actinin, alpha 1	0.032
ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	0.032
HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	0.032
SETD7	SET domain containing (lysine methyltransferase) 7	0.031
HOXA5	homeobox A5	0.031
PTRF	polymerase I and transcript release factor	0.031
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.031
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.031
MN1	meningioma (disrupted in balanced translocation) 1	0.031
CALCA	calcitonin-related polypeptide alpha	0.031
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.031
OAF	OAF homolog (Drosophila)	0.031
SIGLEC7	sialic acid binding Ig-like lectin 7	0.031
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.031
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.031
HOXD8	homeobox D8	0.031
MXD3	MAX dimerization protein 3	0.031
IFNG	interferon, gamma	0.031
MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.031
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.031
CD81	CD81 molecule	0.031
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.031	Human
JAK2	Janus kinase 2	0.031
ASPN	asporin	0.031
ZCCHC24	zinc finger, CCHC domain containing 24	0.031
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.031
HMCN1	hemicentin 1	0.031
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.031
WNT9B	wingless-type MMTV integration site family, member 9B	0.031	Human
DCP1B	DCP1 decapping enzyme homolog B (S. cerevisiae)	0.031
LTBP1	latent transforming growth factor beta binding protein 1	0.030
DOCK8	dedicator of cytokinesis 8	0.030
OLFML3	olfactomedin-like 3	0.030
MAN2B1	mannosidase, alpha, class 2B, member 1	0.030
TMEM30A	transmembrane protein 30A	0.030
EPYC	epiphycan	0.030
NMT2	N-myristoyltransferase 2	0.030
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.030
SCO2	SCO cytochrome oxidase deficient homolog 2 (yeast)	0.030
PYCRL	pyrroline-5-carboxylate reductase-like	0.030
IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1	0.030
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.030
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.030
CDR2L	cerebellar degeneration-related protein 2-like	0.030
ARSI	arylsulfatase family, member I	0.030
ULK1	unc-51-like kinase 1 (C. elegans)	0.030
TRAF3IP2	TRAF3 interacting protein 2	0.030
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.030
PDPN	podoplanin	0.030
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.030
ST5	suppression of tumorigenicity 5	0.030
PCDH7	protocadherin 7	0.030
FOSL1	FOS-like antigen 1	0.030
ICOS	inducible T-cell co-stimulator	0.029
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.029
CHGB	chromogranin B (secretogranin 1)	0.029
LHX2	LIM homeobox 2	0.029
C1QTNF6	C1q and tumor necrosis factor related protein 6	0.029
SFRP1	secreted frizzled-related protein 1	0.029
HPS1	Hermansky-Pudlak syndrome 1	0.029
RBP1	retinol binding protein 1, cellular	0.029
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.029
RAD54L	RAD54-like (S. cerevisiae)	0.029
BNC1	basonuclin 1	0.029
TMTC3	transmembrane and tetratricopeptide repeat containing 3	0.029
FOXO3	forkhead box O3	0.029
FZD2	frizzled homolog 2 (Drosophila)	0.029
VAX2	ventral anterior homeobox 2	0.029
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.029
ATG2A	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.029
ANXA6	annexin A6	0.029
PPARA	peroxisome proliferator-activated receptor alpha	0.029	Human
DOCK7	dedicator of cytokinesis 7	0.029
FMOD	fibromodulin	0.029
CCND1	cyclin D1	0.029
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.029
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.029	Human
GTPBP1	GTP binding protein 1	0.029
WNT5B	wingless-type MMTV integration site family, member 5B	0.029	Human
MAX	MYC associated factor X	0.029
CD40	CD40 molecule, TNF receptor superfamily member 5	0.029	Human
PTPRF	protein tyrosine phosphatase, receptor type, F	0.029
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.029
POU3F1	POU class 3 homeobox 1	0.029
DLX3	distal-less homeobox 3	0.029
CHPF	chondroitin polymerizing factor	0.029
EFNB3	ephrin-B3	0.029
CCNA1	cyclin A1	0.029
LZTS2	leucine zipper, putative tumor suppressor 2	0.029
GEM	GTP binding protein overexpressed in skeletal muscle	0.029
CLCF1	cardiotrophin-like cytokine factor 1	0.029
AKAP11	A kinase (PRKA) anchor protein 11	0.029
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.029
FAM114A1	family with sequence similarity 114, member A1	0.029
PVR	poliovirus receptor	0.029
ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	0.029
IRX5	iroquois homeobox 5	0.029
MPO	myeloperoxidase	0.029
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.029
HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	0.029
SERTAD1	SERTA domain containing 1	0.029
CUL9	cullin 9	0.029
GFI1	growth factor independent 1 transcription repressor	0.029
ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	0.029
IGDCC4	immunoglobulin superfamily, DCC subclass, member 4	0.029
PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme	0.029
PRDM4	PR domain containing 4	0.029
VCAN	versican	0.029	Human
TBC1D2B	TBC1 domain family, member 2B	0.028
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.028
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.028
CIITA	class II, major histocompatibility complex, transactivator	0.028
CCDC80	coiled-coil domain containing 80	0.028
TSC22D4	TSC22 domain family, member 4	0.028
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.028
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.028
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.028
SULF2	sulfatase 2	0.028
GALR2	galanin receptor 2	0.028
KRT14	keratin 14	0.028
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.028
SDC1	syndecan 1	0.028
CLCNKB	chloride channel Kb	0.028
NPY2R	neuropeptide Y receptor Y2	0.028
FAM176B	family with sequence similarity 176, member B	0.028
BDKRB2	bradykinin receptor B2	0.028
PRAME	preferentially expressed antigen in melanoma	0.028
CFHR1	complement factor H-related 1	0.028
CRABP1	cellular retinoic acid binding protein 1	0.028
SPN	sialophorin	0.028
MNX1	motor neuron and pancreas homeobox 1	0.028
TXNDC15	thioredoxin domain containing 15	0.028
ELF4	E74-like factor 4 (ets domain transcription factor)	0.028
ADAM19	ADAM metallopeptidase domain 19	0.028
TLX1	T-cell leukemia homeobox 1	0.028
IL21	interleukin 21	0.028
NAV1	neuron navigator 1	0.028
SOX2	SRY (sex determining region Y)-box 2	0.028	Human
MMP19	matrix metallopeptidase 19	0.028	Human
PLXDC1	plexin domain containing 1	0.028
FGF4	fibroblast growth factor 4	0.028
CSNK1D	casein kinase 1, delta	0.028
CCNO	cyclin O	0.028
PITX2	paired-like homeodomain 2	0.028	Human
ECEL1	endothelin converting enzyme-like 1	0.028
FZD1	frizzled homolog 1 (Drosophila)	0.028
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.028
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.028
SCARF2	scavenger receptor class F, member 2	0.028
SMAD6	SMAD family member 6	0.028
COL9A1	collagen, type IX, alpha 1	0.028
PHF1	PHD finger protein 1	0.028
HES6	hairy and enhancer of split 6 (Drosophila)	0.028	Human
AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)	0.028
COPZ2	coatomer protein complex, subunit zeta 2	0.028
NGFR	nerve growth factor receptor	0.028
NPPB	natriuretic peptide B	0.028
CXCR7	chemokine (C-X-C motif) receptor 7	0.028
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.028
ITGA11	integrin, alpha 11	0.028	Human
RRN3	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)	0.028
SLC38A6	solute carrier family 38, member 6	0.028
CD180	CD180 molecule	0.027	Human
BANP	BTG3 associated nuclear protein	0.027
FLT3	fms-related tyrosine kinase 3	0.027
CA6	carbonic anhydrase VI	0.027	Human
FOXE3	forkhead box E3	0.027
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.027
PAX2	paired box 2	0.027
IL4	interleukin 4	0.027
WDR34	WD repeat domain 34	0.027
IRX4	iroquois homeobox 4	0.027
CD68	CD68 molecule	0.027
SLC30A5	solute carrier family 30 (zinc transporter), member 5	0.027
C2orf88	chromosome 2 open reading frame 88	0.027
LRP5	low density lipoprotein receptor-related protein 5	0.027
P2RY10	purinergic receptor P2Y, G-protein coupled, 10	0.027
NOTCH3	notch 3	0.027
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.027
COL27A1	collagen, type XXVII, alpha 1	0.027
ATG4A	ATG4 autophagy related 4 homolog A (S. cerevisiae)	0.027
IFNB1	interferon, beta 1, fibroblast	0.027
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.027
IL24	interleukin 24	0.027	Human