IMP: Integrative Multi-species Prediction

Homo sapiens

55 genes annotated in human

bone development disease

DOID:0080006

A bone disease that results in abnormal growth and development located in bone or located in cartilage.

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Gene Predictions

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Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "bone development disease" (in gray)

Name	Description	Probability	Func Analog Organism
BMPR1A	bone morphogenetic protein receptor, type IA	1.000	Human
COL1A1	collagen, type I, alpha 1	0.998
FGF1	fibroblast growth factor 1 (acidic)	0.997
COL5A1	collagen, type V, alpha 1	0.983	Human
TJP1	tight junction protein 1 (zona occludens 1)	0.966
COL3A1	collagen, type III, alpha 1	0.921	Human
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.917
FGFR2	fibroblast growth factor receptor 2	0.892
COL6A1	collagen, type VI, alpha 1	0.873
PDIA3	protein disulfide isomerase family A, member 3	0.865
FSTL1	follistatin-like 1	0.830
COL6A2	collagen, type VI, alpha 2	0.829
BMP2	bone morphogenetic protein 2	0.818
PDIA4	protein disulfide isomerase family A, member 4	0.811
FLNA	filamin A, alpha	0.807	Human
BMPR1B	bone morphogenetic protein receptor, type IB	0.795
DDR2	discoidin domain receptor tyrosine kinase 2	0.766
LOX	lysyl oxidase	0.763
COL1A2	collagen, type I, alpha 2	0.761
CHRD	chordin	0.726
COL4A1	collagen, type IV, alpha 1	0.695
FGF10	fibroblast growth factor 10	0.691
PSEN1	presenilin 1	0.688
GDF5	growth differentiation factor 5	0.601
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.599
SETD8	SET domain containing (lysine methyltransferase) 8	0.550
FGF2	fibroblast growth factor 2 (basic)	0.547
BGN	biglycan	0.523
COL4A2	collagen, type IV, alpha 2	0.471
COL5A2	collagen, type V, alpha 2	0.468	Human
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.452
BMP7	bone morphogenetic protein 7	0.414	Human
TROAP	trophinin associated protein (tastin)	0.366
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.356
RPN1	ribophorin I	0.354
SMAD3	SMAD family member 3	0.350
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.343
FN1	fibronectin 1	0.341
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.340
CRELD2	cysteine-rich with EGF-like domains 2	0.338
COL2A1	collagen, type II, alpha 1	0.330
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.330
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.308
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.287
MRC2	mannose receptor, C type 2	0.270
MFAP2	microfibrillar-associated protein 2	0.268
COL11A1	collagen, type XI, alpha 1	0.261	Human
PSEN2	presenilin 2 (Alzheimer disease 4)	0.260
PCOLCE	procollagen C-endopeptidase enhancer	0.257
HSPG2	heparan sulfate proteoglycan 2	0.217
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.213
FKBP10	FK506 binding protein 10, 65 kDa	0.212
SMAD4	SMAD family member 4	0.206
C19orf10	chromosome 19 open reading frame 10	0.202
MSX1	msh homeobox 1	0.201	Human
FBLN2	fibulin 2	0.200
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.198
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.196
KRT8	keratin 8	0.182
NOSTRIN	nitric oxide synthase trafficker	0.182
COL7A1	collagen, type VII, alpha 1	0.181
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.181
PDIA5	protein disulfide isomerase family A, member 5	0.177
NID1	nidogen 1	0.171
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.167
FGFR1	fibroblast growth factor receptor 1	0.162
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.161
C16orf59	chromosome 16 open reading frame 59	0.160
NOG	noggin	0.158
SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	0.157
FGFR3	fibroblast growth factor receptor 3	0.151
FGF7	fibroblast growth factor 7	0.151
LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	0.149
AKAP10	A kinase (PRKA) anchor protein 10	0.149
PXDN	peroxidasin homolog (Drosophila)	0.147
MXRA5	matrix-remodelling associated 5	0.142
COL18A1	collagen, type XVIII, alpha 1	0.137
FRS2	fibroblast growth factor receptor substrate 2	0.137
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.133
IGFBP3	insulin-like growth factor binding protein 3	0.131
ADAM12	ADAM metallopeptidase domain 12	0.126
WISP1	WNT1 inducible signaling pathway protein 1	0.120
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.120
PLXND1	plexin D1	0.117
THY1	Thy-1 cell surface antigen	0.113
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.106
AEBP1	AE binding protein 1	0.101
SUFU	suppressor of fused homolog (Drosophila)	0.101
COL8A2	collagen, type VIII, alpha 2	0.099	Human
NELL2	NEL-like 2 (chicken)	0.098
NID2	nidogen 2 (osteonidogen)	0.096
SKIL	SKI-like oncogene	0.095	Human
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.095
GABARAPL1	GABA(A) receptor-associated protein like 1	0.094
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.092	Human
LEPREL4	leprecan-like 4	0.092
EMILIN1	elastin microfibril interfacer 1	0.089
SMAD1	SMAD family member 1	0.088
COMP	cartilage oligomeric matrix protein	0.087
PDGFA	platelet-derived growth factor alpha polypeptide	0.087
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.087
CALR	calreticulin	0.086
COL5A3	collagen, type V, alpha 3	0.082	Human
UNC5B	unc-5 homolog B (C. elegans)	0.081
ZMYND11	zinc finger, MYND-type containing 11	0.080
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.077
GLI2	GLI family zinc finger 2	0.076	Human
FNDC1	fibronectin type III domain containing 1	0.076
FBLIM1	filamin binding LIM protein 1	0.075
TMED9	transmembrane emp24 protein transport domain containing 9	0.074
ITGB4	integrin, beta 4	0.071
STK36	serine/threonine kinase 36	0.071
COL16A1	collagen, type XVI, alpha 1	0.070	Human
C2orf18	chromosome 2 open reading frame 18	0.069
KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.069
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.068
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.066
ERO1L	ERO1-like (S. cerevisiae)	0.065
FAM64A	family with sequence similarity 64, member A	0.064
HAP1	huntingtin-associated protein 1	0.062
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.060
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.059
SSR4	signal sequence receptor, delta (translocon-associated protein delta)	0.059
TRAM2	translocation associated membrane protein 2	0.059
DLX5	distal-less homeobox 5	0.059
ACAN	aggrecan	0.056
PDIA6	protein disulfide isomerase family A, member 6	0.056
SSR2	signal sequence receptor, beta (translocon-associated protein beta)	0.055
HYOU1	hypoxia up-regulated 1	0.055
LGALS1	lectin, galactoside-binding, soluble, 1	0.054
LEPREL2	leprecan-like 2	0.054	Human
POSTN	periostin, osteoblast specific factor	0.054
PKP4	plakophilin 4	0.053
FOXF2	forkhead box F2	0.053
CSPG4	chondroitin sulfate proteoglycan 4	0.052
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.052
THBS2	thrombospondin 2	0.052	Human
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.052
ECE1	endothelin converting enzyme 1	0.052
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.052
SDF2L1	stromal cell-derived factor 2-like 1	0.051
LAMB2	laminin, beta 2 (laminin S)	0.050
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.050
GLT25D1	glycosyltransferase 25 domain containing 1	0.050
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.050
PLTP	phospholipid transfer protein	0.049
BCL2L1	BCL2-like 1	0.049
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.049
MXRA8	matrix-remodelling associated 8	0.049
EHD2	EH-domain containing 2	0.048
MSX2	msh homeobox 2	0.046
CRLF1	cytokine receptor-like factor 1	0.046
TSPAN4	tetraspanin 4	0.046
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.046
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.045	Human
SOX11	SRY (sex determining region Y)-box 11	0.045	Human
GPC1	glypican 1	0.045
FKBP2	FK506 binding protein 2, 13kDa	0.044
PRRX2	paired related homeobox 2	0.044
TJP2	tight junction protein 2 (zona occludens 2)	0.044
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.043
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.043
NTM	neurotrimin	0.043
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.043
PTK7	PTK7 protein tyrosine kinase 7	0.042
CRABP2	cellular retinoic acid binding protein 2	0.042
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.042
NCSTN	nicastrin	0.042
FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	0.041
SFRP2	secreted frizzled-related protein 2	0.041
ZBED1	zinc finger, BED-type containing 1	0.041
C9orf140	chromosome 9 open reading frame 140	0.041
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.041
TNC	tenascin C	0.041
COL9A3	collagen, type IX, alpha 3	0.040	Human
RBM11	RNA binding motif protein 11	0.040
LRRC15	leucine rich repeat containing 15	0.040
FOXD1	forkhead box D1	0.040
CHTF18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.040
RHOXF2	Rhox homeobox family, member 2	0.040
CKAP4	cytoskeleton-associated protein 4	0.040
VMP1	vacuole membrane protein 1	0.039
FAP	fibroblast activation protein, alpha	0.039
LAMA5	laminin, alpha 5	0.038
LOXL1	lysyl oxidase-like 1	0.038
GPR161	G protein-coupled receptor 161	0.037
PDLIM4	PDZ and LIM domain 4	0.037
PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	0.037	Human
LUM	lumican	0.037
GLI3	GLI family zinc finger 3	0.037
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.036
RHOD	ras homolog gene family, member D	0.036
INHBA	inhibin, beta A	0.036
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.035
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.034
CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	0.034
SRI	sorcin	0.034
SFRP4	secreted frizzled-related protein 4	0.034
LOXL2	lysyl oxidase-like 2	0.034
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.034
BMP1	bone morphogenetic protein 1	0.034
OLFML2B	olfactomedin-like 2B	0.034
GAS1	growth arrest-specific 1	0.034
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.034
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.033
BMP8A	bone morphogenetic protein 8a	0.033	Human
COPG	coatomer protein complex, subunit gamma	0.033
HYAL1	hyaluronoglucosaminidase 1	0.032
COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	0.032
SETD7	SET domain containing (lysine methyltransferase) 7	0.031
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.031
COL10A1	collagen, type X, alpha 1	0.031
ZFYVE9	zinc finger, FYVE domain containing 9	0.031
CD248	CD248 molecule, endosialin	0.031
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.031
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.030
HAS2	hyaluronan synthase 2	0.030
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.030
C14orf80	chromosome 14 open reading frame 80	0.030
C5orf22	chromosome 5 open reading frame 22	0.029
FBN1	fibrillin 1	0.029
HMGA2	high mobility group AT-hook 2	0.029
THBS3	thrombospondin 3	0.029	Human
RUNX2	runt-related transcription factor 2	0.029
CHPF	chondroitin polymerizing factor	0.029
CTHRC1	collagen triple helix repeat containing 1	0.029
WNT5A	wingless-type MMTV integration site family, member 5A	0.029	Human
HOXD9	homeobox D9	0.029
HOXD11	homeobox D11	0.028
CLASRP	CLK4-associating serine/arginine rich protein	0.028
SND1	staphylococcal nuclease and tudor domain containing 1	0.028
COL6A3	collagen, type VI, alpha 3	0.028
SDC1	syndecan 1	0.028
TWIST1	twist homolog 1 (Drosophila)	0.028
PAM	peptidylglycine alpha-amidating monooxygenase	0.028
GLT8D2	glycosyltransferase 8 domain containing 2	0.028
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.028
MAPK8	mitogen-activated protein kinase 8	0.028
PLXDC1	plexin domain containing 1	0.028
PYCR1	pyrroline-5-carboxylate reductase 1	0.028
CLDN7	claudin 7	0.028
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.028
GJD3	gap junction protein, delta 3, 31.9kDa	0.028
TGFB2	transforming growth factor, beta 2	0.028
SCARF2	scavenger receptor class F, member 2	0.028
P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	0.028
NKX3-2	NK3 homeobox 2	0.027
SMAD2	SMAD family member 2	0.027
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.027
EPHB2	EPH receptor B2	0.027
GDF6	growth differentiation factor 6	0.027	Human
SHOX2	short stature homeobox 2	0.027
RADIL	Ras association and DIL domains	0.027
C2orf88	chromosome 2 open reading frame 88	0.027
KRT16	keratin 16	0.026
E2F2	E2F transcription factor 2	0.026
PAQR4	progestin and adipoQ receptor family member IV	0.026
SMAD5	SMAD family member 5	0.026
E2F1	E2F transcription factor 1	0.026
EPYC	epiphycan	0.026
LMNA	lamin A/C	0.026
KAT2B	K(lysine) acetyltransferase 2B	0.025
FGF8	fibroblast growth factor 8 (androgen-induced)	0.025
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.025
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.025
BNC2	basonuclin 2	0.025
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.025
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.025
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.025
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.025
PLCG1	phospholipase C, gamma 1	0.025
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.025
WNT11	wingless-type MMTV integration site family, member 11	0.025	Human
RAD54L	RAD54-like (S. cerevisiae)	0.024
MDK	midkine (neurite growth-promoting factor 2)	0.024
SH3PXD2A	SH3 and PX domains 2A	0.024
MFGE8	milk fat globule-EGF factor 8 protein	0.024
HM13	histocompatibility (minor) 13	0.024
TGFBR1	transforming growth factor, beta receptor 1	0.024	Human
ANXA6	annexin A6	0.024
HTRA1	HtrA serine peptidase 1	0.024
CCDC17	coiled-coil domain containing 17	0.024
ERO1LB	ERO1-like beta (S. cerevisiae)	0.024
SMAD6	SMAD family member 6	0.024
COPZ2	coatomer protein complex, subunit zeta 2	0.024
TPBG	trophoblast glycoprotein	0.023
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.023
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.023	Human
EPHB3	EPH receptor B3	0.023
LAMB1	laminin, beta 1	0.023
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.023
ITGB7	integrin, beta 7	0.023
STC1	stanniocalcin 1	0.023
MEAF6	MYST/Esa1-associated factor 6	0.023
GPX7	glutathione peroxidase 7	0.023
ANGPTL2	angiopoietin-like 2	0.023
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.023
CREB3L1	cAMP responsive element binding protein 3-like 1	0.023
PTRF	polymerase I and transcript release factor	0.023
NPTX2	neuronal pentraxin II	0.023
ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)	0.023
COL14A1	collagen, type XIV, alpha 1	0.022
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.022
SPON2	spondin 2, extracellular matrix protein	0.022
CUX1	cut-like homeobox 1	0.022
ECM1	extracellular matrix protein 1	0.022
EXT2	exostosin 2	0.022
SP1	Sp1 transcription factor	0.022
PDGFRL	platelet-derived growth factor receptor-like	0.022
EFNB3	ephrin-B3	0.022
CDX2	caudal type homeobox 2	0.022
HES6	hairy and enhancer of split 6 (Drosophila)	0.022	Human
MXD3	MAX dimerization protein 3	0.022
SMO	smoothened homolog (Drosophila)	0.022
HR	hairless homolog (mouse)	0.022
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.022
EXT1	exostosin 1	0.022
PYCRL	pyrroline-5-carboxylate reductase-like	0.022
MAG	myelin associated glycoprotein	0.022
STBD1	starch binding domain 1	0.022
KRT18	keratin 18	0.022
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.022
FZD8	frizzled homolog 8 (Drosophila)	0.021
HOXA11	homeobox A11	0.021
FOXC1	forkhead box C1	0.021
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.021
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.021
ARTN	artemin	0.021
MBIP	MAP3K12 binding inhibitory protein 1	0.021
C1QTNF6	C1q and tumor necrosis factor related protein 6	0.021
TGFB3	transforming growth factor, beta 3	0.021
COL9A1	collagen, type IX, alpha 1	0.021
POLE	polymerase (DNA directed), epsilon	0.021
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.021	Human
PLEKHA4	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4	0.021
FZD2	frizzled homolog 2 (Drosophila)	0.021
WNT2	wingless-type MMTV integration site family member 2	0.021	Human
ACTN4	actinin, alpha 4	0.021
KRT14	keratin 14	0.020
ZCCHC24	zinc finger, CCHC domain containing 24	0.020
NRP1	neuropilin 1	0.020
CLEC11A	C-type lectin domain family 11, member A	0.020
VASN	vasorin	0.020
PRRX1	paired related homeobox 1	0.020
LBX1	ladybird homeobox 1	0.020
TAGLN	transgelin	0.020
PPIC	peptidylprolyl isomerase C (cyclophilin C)	0.020	Human
HOXC6	homeobox C6	0.020
TBX2	T-box 2	0.020
SHB	Src homology 2 domain containing adaptor protein B	0.020
SOX10	SRY (sex determining region Y)-box 10	0.020	Human
IL11	interleukin 11	0.020
C17orf53	chromosome 17 open reading frame 53	0.020
TM9SF2	transmembrane 9 superfamily member 2	0.020
SULF1	sulfatase 1	0.020
SNAI2	snail homolog 2 (Drosophila)	0.020
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.020
PDCD7	programmed cell death 7	0.020
INSR	insulin receptor	0.020
SLC25A13	solute carrier family 25, member 13 (citrin)	0.020
MYH9	myosin, heavy chain 9, non-muscle	0.020
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.019
USP18	ubiquitin specific peptidase 18	0.019
TSPAN9	tetraspanin 9	0.019
IDUA	iduronidase, alpha-L-	0.019
GLG1	golgi glycoprotein 1	0.019
PCDH7	protocadherin 7	0.019
CD276	CD276 molecule	0.019
RBPMS	RNA binding protein with multiple splicing	0.019
DACH1	dachshund homolog 1 (Drosophila)	0.019
KAL1	Kallmann syndrome 1 sequence	0.019
LAMA4	laminin, alpha 4	0.019
WT1	Wilms tumor 1	0.019
OCLN	occludin	0.019
FAM46D	family with sequence similarity 46, member D	0.019
CRABP1	cellular retinoic acid binding protein 1	0.019
PTPRU	protein tyrosine phosphatase, receptor type, U	0.019
CDR2L	cerebellar degeneration-related protein 2-like	0.019
AKAP11	A kinase (PRKA) anchor protein 11	0.019
WNT5B	wingless-type MMTV integration site family, member 5B	0.019	Human
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.019	Human
ISG15	ISG15 ubiquitin-like modifier	0.019
RYK	RYK receptor-like tyrosine kinase	0.019
PDPN	podoplanin	0.019
WIF1	WNT inhibitory factor 1	0.019
HTRA3	HtrA serine peptidase 3	0.019
FGD1	FYVE, RhoGEF and PH domain containing 1	0.018
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.018
GANAB	glucosidase, alpha; neutral AB	0.018
BDKRB1	bradykinin receptor B1	0.018
OLFML3	olfactomedin-like 3	0.018
COL9A2	collagen, type IX, alpha 2	0.018
INHBB	inhibin, beta B	0.018
TWIST2	twist homolog 2 (Drosophila)	0.018
MSC	musculin	0.018
NLK	nemo-like kinase	0.018
MSLN	mesothelin	0.018
VAX2	ventral anterior homeobox 2	0.018
BMP4	bone morphogenetic protein 4	0.018	Human
AKAP1	A kinase (PRKA) anchor protein 1	0.018
SOX9	SRY (sex determining region Y)-box 9	0.018
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.018
HOXC5	homeobox C5	0.018
NBL1	neuroblastoma, suppression of tumorigenicity 1	0.018
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.018	Human
COL27A1	collagen, type XXVII, alpha 1	0.018
COL13A1	collagen, type XIII, alpha 1	0.018
LHX2	LIM homeobox 2	0.018
DOCK9	dedicator of cytokinesis 9	0.018
PMEPA1	prostate transmembrane protein, androgen induced 1	0.018
ADRA1D	adrenergic, alpha-1D-, receptor	0.018
FZD7	frizzled homolog 7 (Drosophila)	0.018
CHN2	chimerin (chimaerin) 2	0.018
HES5	hairy and enhancer of split 5 (Drosophila)	0.018	Human
FOXO3	forkhead box O3	0.018
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.018
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.018
CA12	carbonic anhydrase XII	0.018
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.018
RABL3	RAB, member of RAS oncogene family-like 3	0.018
MNX1	motor neuron and pancreas homeobox 1	0.018
PITX2	paired-like homeodomain 2	0.017	Human
LIMK1	LIM domain kinase 1	0.017
LAMB3	laminin, beta 3	0.017
KIAA1644	KIAA1644	0.017
CLCF1	cardiotrophin-like cytokine factor 1	0.017
DTX2	deltex homolog 2 (Drosophila)	0.017
COL12A1	collagen, type XII, alpha 1	0.017
GPX8	glutathione peroxidase 8 (putative)	0.017
TMED3	transmembrane emp24 protein transport domain containing 3	0.017
DBN1	drebrin 1	0.017
HOXD13	homeobox D13	0.017
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.017
AKAP12	A kinase (PRKA) anchor protein 12	0.017
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.017
MTMR4	myotubularin related protein 4	0.017
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.017
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.017
SLC16A1	solute carrier family 16, member 1 (monocarboxylic acid transporter 1)	0.017
HAPLN1	hyaluronan and proteoglycan link protein 1	0.017
CHIC2	cysteine-rich hydrophobic domain 2	0.017
TMEM119	transmembrane protein 119	0.017
KIRREL	kin of IRRE like (Drosophila)	0.017
NAV3	neuron navigator 3	0.017
HAND2	heart and neural crest derivatives expressed 2	0.017	Human
EXOC5	exocyst complex component 5	0.017
CD70	CD70 molecule	0.017
NRP2	neuropilin 2	0.017
FOXO1	forkhead box O1	0.017
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.017
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.017
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.017
TRIO	triple functional domain (PTPRF interacting)	0.017
ASPN	asporin	0.017
LRRC17	leucine rich repeat containing 17	0.017
NCAPH2	non-SMC condensin II complex, subunit H2	0.017
SLMO1	slowmo homolog 1 (Drosophila)	0.017
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.017
SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.017
CDHR5	cadherin-related family member 5	0.017
NPTN	neuroplastin	0.017
TRO	trophinin	0.017
PLXNA1	plexin A1	0.017
CCDC80	coiled-coil domain containing 80	0.017
EN1	engrailed homeobox 1	0.016
CPXM1	carboxypeptidase X (M14 family), member 1	0.016
CD99	CD99 molecule	0.016
AQP5	aquaporin 5	0.016
WNT3	wingless-type MMTV integration site family, member 3	0.016	Human
GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	0.016
ODZ3	odz, odd Oz/ten-m homolog 3 (Drosophila)	0.016
EDNRA	endothelin receptor type A	0.016
NRTN	neurturin	0.016
GAL	galanin prepropeptide	0.016
DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)	0.016
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.016	Human
MATN3	matrilin 3	0.016
RPN2	ribophorin II	0.016
WDR62	WD repeat domain 62	0.016
IRX5	iroquois homeobox 5	0.016
FBN2	fibrillin 2	0.016
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.016
DUSP9	dual specificity phosphatase 9	0.016
IGFBP4	insulin-like growth factor binding protein 4	0.016
PAEP	progestagen-associated endometrial protein	0.016
ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	0.016
RARG	retinoic acid receptor, gamma	0.016
PYY	peptide YY	0.016
HOXC8	homeobox C8	0.016
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.016
SLC25A10	solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10	0.016
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.016
FOXJ1	forkhead box J1	0.016
FLNC	filamin C, gamma	0.016	Human
RAB34	RAB34, member RAS oncogene family	0.016
FYTTD1	forty-two-three domain containing 1	0.016
CSNK1D	casein kinase 1, delta	0.016
SAP30L	SAP30-like	0.016
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.016
TBX3	T-box 3	0.016
LAMA1	laminin, alpha 1	0.016
EFNB1	ephrin-B1	0.016
CCNO	cyclin O	0.016
PAX5	paired box 5	0.016
TXNDC5	thioredoxin domain containing 5 (endoplasmic reticulum)	0.016
PRAME	preferentially expressed antigen in melanoma	0.016
DUSP4	dual specificity phosphatase 4	0.016
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.016
HOXA5	homeobox A5	0.016
C7orf10	chromosome 7 open reading frame 10	0.016
SLC39A6	solute carrier family 39 (zinc transporter), member 6	0.016
HOXD10	homeobox D10	0.016
PRMT2	protein arginine methyltransferase 2	0.016
FGFR4	fibroblast growth factor receptor 4	0.015	Human
IGDCC4	immunoglobulin superfamily, DCC subclass, member 4	0.015
FGF18	fibroblast growth factor 18	0.015
ARSI	arylsulfatase family, member I	0.015
C19orf26	chromosome 19 open reading frame 26	0.015
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.015
GSX1	GS homeobox 1	0.015
MYBL2	v-myb myeloblastosis viral oncogene homolog (avian)-like 2	0.015
DLX4	distal-less homeobox 4	0.015
TEAD2	TEA domain family member 2	0.015
LRP4	low density lipoprotein receptor-related protein 4	0.015
SIX3	SIX homeobox 3	0.015
CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)	0.015
STRA6	stimulated by retinoic acid gene 6 homolog (mouse)	0.015
TIMP2	TIMP metallopeptidase inhibitor 2	0.015
RCN1	reticulocalbin 1, EF-hand calcium binding domain	0.015
HOXB13	homeobox B13	0.015	Human
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.015
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.015
ANTXR1	anthrax toxin receptor 1	0.015
WDR34	WD repeat domain 34	0.015
C11orf24	chromosome 11 open reading frame 24	0.015
ZBED5	zinc finger, BED-type containing 5	0.015
TONSL	tonsoku-like, DNA repair protein	0.015
WNT4	wingless-type MMTV integration site family, member 4	0.015	Human
SEC23A	Sec23 homolog A (S. cerevisiae)	0.015
CAMKK2	calcium/calmodulin-dependent protein kinase kinase 2, beta	0.015
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.015
DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11	0.015
PAX6	paired box 6	0.015
KRT17	keratin 17	0.015
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.015
SCARA3	scavenger receptor class A, member 3	0.015
MN1	meningioma (disrupted in balanced translocation) 1	0.015
HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	0.015
MAGEA5	melanoma antigen family A, 5	0.015
ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	0.015
DLX3	distal-less homeobox 3	0.015
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.015
BFSP1	beaded filament structural protein 1, filensin	0.015
ST5	suppression of tumorigenicity 5	0.015
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.015
CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14	0.015
SOX2	SRY (sex determining region Y)-box 2	0.015	Human
COL17A1	collagen, type XVII, alpha 1	0.015
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.015
LAT	linker for activation of T cells	0.015
NCOA6	nuclear receptor coactivator 6	0.015
PRPH	peripherin	0.015
SRPX2	sushi-repeat containing protein, X-linked 2	0.015
COL4A6	collagen, type IV, alpha 6	0.015
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.015
CELSR1	cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)	0.015
NNAT	neuronatin	0.014
CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.014
PRKX	protein kinase, X-linked	0.014
BARX2	BARX homeobox 2	0.014
RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	0.014
F2R	coagulation factor II (thrombin) receptor	0.014
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.014
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.014
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.014
HOXC13	homeobox C13	0.014	Human
CNIH3	cornichon homolog 3 (Drosophila)	0.014
LTK	leukocyte receptor tyrosine kinase	0.014
TMEM158	transmembrane protein 158 (gene/pseudogene)	0.014
DOCK1	dedicator of cytokinesis 1	0.014
ATL2	atlastin GTPase 2	0.014
ZNF469	zinc finger protein 469	0.014
FJX1	four jointed box 1 (Drosophila)	0.014
DCLK1	doublecortin-like kinase 1	0.014
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.014
IGDCC3	immunoglobulin superfamily, DCC subclass, member 3	0.014
FGF9	fibroblast growth factor 9 (glia-activating factor)	0.014
NOX4	NADPH oxidase 4	0.014
HOXC11	homeobox C11	0.014
DEDD	death effector domain containing	0.014
SNAI1	snail homolog 1 (Drosophila)	0.014
LRRC45	leucine rich repeat containing 45	0.014
ADAMTS7	ADAM metallopeptidase with thrombospondin type 1 motif, 7	0.014
NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2	0.014
GPR1	G protein-coupled receptor 1	0.014
SYPL1	synaptophysin-like 1	0.014
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.014
SLC19A2	solute carrier family 19 (thiamine transporter), member 2	0.014
GLI1	GLI family zinc finger 1	0.014	Human
WNT7B	wingless-type MMTV integration site family, member 7B	0.014	Human
ITM2C	integral membrane protein 2C	0.014
KRT75	keratin 75	0.014
KCTD15	potassium channel tetramerisation domain containing 15	0.014
NPAS2	neuronal PAS domain protein 2	0.014
PVR	poliovirus receptor	0.014
SIX1	SIX homeobox 1	0.014
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.014
VASH2	vasohibin 2	0.014
RABAC1	Rab acceptor 1 (prenylated)	0.014
FERMT1	fermitin family member 1	0.014
GREM1	gremlin 1	0.014
EMX2	empty spiracles homeobox 2	0.014
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.014
EYA2	eyes absent homolog 2 (Drosophila)	0.014
NPR2	natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)	0.014
TRAIP	TRAF interacting protein	0.014
EMID1	EMI domain containing 1	0.014
CST4	cystatin S	0.014
OSR2	odd-skipped related 2 (Drosophila)	0.014
ITGA11	integrin, alpha 11	0.014
PML	promyelocytic leukemia	0.014
PPL	periplakin	0.014
ZNF780A	zinc finger protein 780A	0.014
TH	tyrosine hydroxylase	0.014
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.014
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.014
CD63	CD63 molecule	0.014
HS2ST1	heparan sulfate 2-O-sulfotransferase 1	0.014
GXYLT2	glucoside xylosyltransferase 2	0.014
WNT10A	wingless-type MMTV integration site family, member 10A	0.014	Human
CREBL2	cAMP responsive element binding protein-like 2	0.014
NEU4	sialidase 4	0.014
SEC14L2	SEC14-like 2 (S. cerevisiae)	0.014
CTF1	cardiotrophin 1	0.014
GLDC	glycine dehydrogenase (decarboxylating)	0.014
DCP1B	DCP1 decapping enzyme homolog B (S. cerevisiae)	0.014
HPDL	4-hydroxyphenylpyruvate dioxygenase-like	0.014
CARD10	caspase recruitment domain family, member 10	0.014
TGIF1	TGFB-induced factor homeobox 1	0.014
ZEB2	zinc finger E-box binding homeobox 2	0.014
BAI2	brain-specific angiogenesis inhibitor 2	0.014
PHLDA3	pleckstrin homology-like domain, family A, member 3	0.014
IGSF3	immunoglobulin superfamily, member 3	0.014
PRKCDBP	protein kinase C, delta binding protein	0.014
EFNA3	ephrin-A3	0.014
FOXQ1	forkhead box Q1	0.014
CNKSR1	connector enhancer of kinase suppressor of Ras 1	0.014
TNNT1	troponin T type 1 (skeletal, slow)	0.014
BANP	BTG3 associated nuclear protein	0.014
FOXG1	forkhead box G1	0.014
RHOA	ras homolog gene family, member A	0.014
PDE4B	phosphodiesterase 4B, cAMP-specific	0.014	Human
AHSG	alpha-2-HS-glycoprotein	0.014
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.014
GLIS2	GLIS family zinc finger 2	0.013	Human
LEF1	lymphoid enhancer-binding factor 1	0.013
COL8A1	collagen, type VIII, alpha 1	0.013	Human
SALL1	sal-like 1 (Drosophila)	0.013
SIM2	single-minded homolog 2 (Drosophila)	0.013
TRIM16	tripartite motif containing 16	0.013
PTGFR	prostaglandin F receptor (FP)	0.013
PTPRF	protein tyrosine phosphatase, receptor type, F	0.013
DNM1	dynamin 1	0.013
ADAMTS14	ADAM metallopeptidase with thrombospondin type 1 motif, 14	0.013
NRM	nurim (nuclear envelope membrane protein)	0.013
PAX9	paired box 9	0.013
CSRP2	cysteine and glycine-rich protein 2	0.013
FZD1	frizzled homolog 1 (Drosophila)	0.013
EDEM2	ER degradation enhancer, mannosidase alpha-like 2	0.013
KRT13	keratin 13	0.013
FEV	FEV (ETS oncogene family)	0.013
ZBTB6	zinc finger and BTB domain containing 6	0.013
FOXA1	forkhead box A1	0.013
SERINC3	serine incorporator 3	0.013
ESM1	endothelial cell-specific molecule 1	0.013
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.013
PAX2	paired box 2	0.013
MICALL2	MICAL-like 2	0.013
KCNC4	potassium voltage-gated channel, Shaw-related subfamily, member 4	0.013
ETV4	ets variant 4	0.013
KIAA1199	KIAA1199	0.013
NOS3	nitric oxide synthase 3 (endothelial cell)	0.013
SALL2	sal-like 2 (Drosophila)	0.013
INPP4B	inositol polyphosphate-4-phosphatase, type II, 105kDa	0.013
RNF215	ring finger protein 215	0.013
WNT10B	wingless-type MMTV integration site family, member 10B	0.013	Human
SLC20A2	solute carrier family 20 (phosphate transporter), member 2	0.013
UNC5C	unc-5 homolog C (C. elegans)	0.013
ENC1	ectodermal-neural cortex 1 (with BTB-like domain)	0.013
CST1	cystatin SN	0.013
MIA	melanoma inhibitory activity	0.013
NES	nestin	0.013
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.013
EFNB2	ephrin-B2	0.013
SULF2	sulfatase 2	0.013
BACE2	beta-site APP-cleaving enzyme 2	0.013
CLDN1	claudin 1	0.013
IRX3	iroquois homeobox 3	0.013
FST	follistatin	0.013
ULBP2	UL16 binding protein 2	0.013
SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.013
CIB1	calcium and integrin binding 1 (calmyrin)	0.013
DSP	desmoplakin	0.013
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.013
CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	0.013	Human
S100A3	S100 calcium binding protein A3	0.013
MMP7	matrix metallopeptidase 7 (matrilysin, uterine)	0.013	Human
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.013
WNK4	WNK lysine deficient protein kinase 4	0.013
PTHLH	parathyroid hormone-like hormone	0.013
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.013
BDKRB2	bradykinin receptor B2	0.013
PLSCR3	phospholipid scramblase 3	0.013
LZTR1	leucine-zipper-like transcription regulator 1	0.013
LMF2	lipase maturation factor 2	0.013
DSC3	desmocollin 3	0.013
NTN3	netrin 3	0.013
MGAT5B	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B	0.013
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.013
KIAA1024	KIAA1024	0.013
BOC	Boc homolog (mouse)	0.013
EVPL	envoplakin	0.013
PREPL	prolyl endopeptidase-like	0.013
TNFRSF10D	tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain	0.013
AZI1	5-azacytidine induced 1	0.013
GABRE	gamma-aminobutyric acid (GABA) A receptor, epsilon	0.013
ATP8B2	ATPase, class I, type 8B, member 2	0.013
LZTS2	leucine zipper, putative tumor suppressor 2	0.013
DOCK8	dedicator of cytokinesis 8	0.013
GJC1	gap junction protein, gamma 1, 45kDa	0.013
C3orf52	chromosome 3 open reading frame 52	0.013
ZNF41	zinc finger protein 41	0.013
FBXO17	F-box protein 17	0.013
SLC4A3	solute carrier family 4, anion exchanger, member 3	0.013
PIGM	phosphatidylinositol glycan anchor biosynthesis, class M	0.013
C5orf62	chromosome 5 open reading frame 62	0.013
MAX	MYC associated factor X	0.013
HSF2BP	heat shock transcription factor 2 binding protein	0.013
PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor	0.013
CCDC8	coiled-coil domain containing 8	0.013
PPEF1	protein phosphatase, EF-hand calcium binding domain 1	0.013
ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17	0.013
ADA	adenosine deaminase	0.013
DUSP10	dual specificity phosphatase 10	0.013
LLGL1	lethal giant larvae homolog 1 (Drosophila)	0.013
FOXH1	forkhead box H1	0.013
EVC	Ellis van Creveld syndrome	0.013
THAP11	THAP domain containing 11	0.013
RHBDD3	rhomboid domain containing 3	0.013
TMSB10	thymosin beta 10	0.013