IMP: Integrative Multi-species Prediction

Homo sapiens

27 genes annotated in human

spinocerebellar degeneration

DOID:2478

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "spinocerebellar degeneration"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "spinocerebellar degeneration" (in gray)

Name	Description	Probability	Func Analog Organism
NOXA1	NADPH oxidase activator 1	0.323
SKA3	spindle and kinetochore associated complex subunit 3	0.231
RHOXF2	Rhox homeobox family, member 2	0.163
ATN1	atrophin 1	0.149
SH3GL2	SH3-domain GRB2-like 2	0.142
GFI1B	growth factor independent 1B transcription repressor	0.137
SUN2	Sad1 and UNC84 domain containing 2	0.121
LTBP4	latent transforming growth factor beta binding protein 4	0.079
PICK1	protein interacting with PRKCA 1	0.071
CEP164	centrosomal protein 164kDa	0.060
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.055	Human
C16orf70	chromosome 16 open reading frame 70	0.052
MEGF8	multiple EGF-like-domains 8	0.046
SUN1	Sad1 and UNC84 domain containing 1	0.040
ATM	ataxia telangiectasia mutated	0.038
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.038
TAF1C	TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa	0.037
TUBB2B	tubulin, beta 2B	0.036
GIGYF1	GRB10 interacting GYF protein 1	0.033
TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	0.032
TP53BP2	tumor protein p53 binding protein, 2	0.032
NUMBL	numb homolog (Drosophila)-like	0.032
DISC1	disrupted in schizophrenia 1	0.030
SERTAD4	SERTA domain containing 4	0.030
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.026
CACNA1A	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	0.025
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.025
AGRN	agrin	0.024
FBLN1	fibulin 1	0.024
AKAP1	A kinase (PRKA) anchor protein 1	0.023
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.023
MAGED1	melanoma antigen family D, 1	0.021
APC	adenomatous polyposis coli	0.021
TAF1B	TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa	0.021
ATXN1	ataxin 1	0.020
DPH2	DPH2 homolog (S. cerevisiae)	0.020
TRRAP	transformation/transcription domain-associated protein	0.018
MEGF11	multiple EGF-like-domains 11	0.018
MEGF6	multiple EGF-like-domains 6	0.018
KALRN	kalirin, RhoGEF kinase	0.018
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.017
LPHN1	latrophilin 1	0.017
SH3GL3	SH3-domain GRB2-like 3	0.017
DNAJA3	DnaJ (Hsp40) homolog, subfamily A, member 3	0.017
ATXN2L	ataxin 2-like	0.017
ATXN7	ataxin 7	0.016
ARHGAP22	Rho GTPase activating protein 22	0.016
TSFM	Ts translation elongation factor, mitochondrial	0.016
ZHX3	zinc fingers and homeoboxes 3	0.016
AMFR	autocrine motility factor receptor	0.016
TAF12	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa	0.015
USP50	ubiquitin specific peptidase 50	0.015
TRIM32	tripartite motif containing 32	0.015
GTF2A1	general transcription factor IIA, 1, 19/37kDa	0.015
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	0.015
PIAS1	protein inhibitor of activated STAT, 1	0.014
ZCCHC6	zinc finger, CCHC domain containing 6	0.014
ERN1	endoplasmic reticulum to nucleus signaling 1	0.014
R3HDM2	R3H domain containing 2	0.014
TAF10	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa	0.014
DNAJB5	DnaJ (Hsp40) homolog, subfamily B, member 5	0.013
ACTN2	actinin, alpha 2	0.013
ZFAND5	zinc finger, AN1-type domain 5	0.013
IMMT	inner membrane protein, mitochondrial	0.013
RNMTL1	RNA methyltransferase like 1	0.013
DAZAP2	DAZ associated protein 2	0.013
STARD7	StAR-related lipid transfer (START) domain containing 7	0.012
SYNE2	spectrin repeat containing, nuclear envelope 2	0.012	Human
QKI	quaking homolog, KH domain RNA binding (mouse)	0.012
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.012
ACTN1	actinin, alpha 1	0.012
KIAA0174	KIAA0174	0.012
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.011
POLR1E	polymerase (RNA) I polypeptide E, 53kDa	0.011
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.011
KIAA1279	KIAA1279	0.011
CCNK	cyclin K	0.011
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.011
BZRAP1	benzodiazapine receptor (peripheral) associated protein 1	0.011
BCAR1	breast cancer anti-estrogen resistance 1	0.011
SDHA	succinate dehydrogenase complex, subunit A, flavoprotein (Fp)	0.011
BRF1	BRF1 homolog, subunit of RNA polymerase III transcription initiation factor IIIB (S. cerevisiae)	0.011
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.011
RPUSD4	RNA pseudouridylate synthase domain containing 4	0.011
NELL2	NEL-like 2 (chicken)	0.011
UBXN2A	UBX domain protein 2A	0.011
TRAF6	TNF receptor-associated factor 6	0.011
ABCA2	ATP-binding cassette, sub-family A (ABC1), member 2	0.011
KIAA2026	KIAA2026	0.011
RPUSD2	RNA pseudouridylate synthase domain containing 2	0.011
XPC	xeroderma pigmentosum, complementation group C	0.011
MAP7D1	MAP7 domain containing 1	0.011
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.011
RBPMS	RNA binding protein with multiple splicing	0.010
MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	0.010
SUPV3L1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.010
STARD13	StAR-related lipid transfer (START) domain containing 13	0.010
SELRC1	Sel1 repeat containing 1	0.010
MRPS9	mitochondrial ribosomal protein S9	0.010
HECW1	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1	0.010
POLR1C	polymerase (RNA) I polypeptide C, 30kDa	0.010
TBC1D5	TBC1 domain family, member 5	0.010
FAM193A	family with sequence similarity 193, member A	0.010
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.010
TXNDC11	thioredoxin domain containing 11	0.010
MATN2	matrilin 2	0.010
FAM46A	family with sequence similarity 46, member A	0.010
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.010
PRKCG	protein kinase C, gamma	0.007
ITPR1	inositol 1,4,5-trisphosphate receptor, type 1	0.006
PDYN	prodynorphin	0.005
AFG3L2	AFG3 ATPase family gene 3-like 2 (S. cerevisiae)	0.005
SPTBN2	spectrin, beta, non-erythrocytic 2	0.005
FGF14	fibroblast growth factor 14	0.005
SYNE1	spectrin repeat containing, nuclear envelope 1	0.005
ATXN2	ataxin 2	0.005
TTBK2	tau tubulin kinase 2	0.004
ADCK3	aarF domain containing kinase 3	0.004
ZNF592	zinc finger protein 592	0.004
SETX	senataxin	0.004
BEAN1	brain expressed, associated with NEDD4, 1	0.004
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.004
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.003
C10orf2	chromosome 10 open reading frame 2	0.003
FXN	frataxin	0.003
ATXN3	ataxin 3	0.003
ABCB7	ATP-binding cassette, sub-family B (MDR/TAP), member 7	0.003
TBP	TATA box binding protein	0.002
ATXN10	ataxin 10	0.002
ATXN8	ataxin 8	0.001
TDP1	tyrosyl-DNA phosphodiesterase 1	0.001