IMP: Integrative Multi-species Prediction

Homo sapiens

379 genes annotated in human

cellular response to dna damage stimulus

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "cellular response to dna damage stimulus"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "cellular response to dna damage stimulus" (in gray)

Name	Description	Probability	Func Analog Organism
TP53	tumor protein p53	1.000
BRCA1	breast cancer 1, early onset	1.000
MDM2	Mdm2 p53 binding protein homolog (mouse)	1.000
PCNA	proliferating cell nuclear antigen	1.000
H2AFX	H2A histone family, member X	1.000
CHEK1	CHK1 checkpoint homolog (S. pombe)	1.000
RB1	retinoblastoma 1	1.000
BLM	Bloom syndrome, RecQ helicase-like	1.000
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	1.000
CDK2	cyclin-dependent kinase 2	1.000	Yeast
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	1.000
RPA1	replication protein A1, 70kDa	1.000
CHEK2	CHK2 checkpoint homolog (S. pombe)	1.000
CREBBP	CREB binding protein	1.000	Human
HDAC1	histone deacetylase 1	1.000
XRCC5	X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)	1.000
RAD50	RAD50 homolog (S. cerevisiae)	1.000
MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	1.000
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	1.000	Human Yeast
PARP1	poly (ADP-ribose) polymerase 1	1.000
MSH6	mutS homolog 6 (E. coli)	0.999
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.999
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.999
MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	0.999
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.999
HNRNPK	heterogeneous nuclear ribonucleoprotein K	0.999	Mouse Worm
NBN	nibrin	0.999
E2F1	E2F transcription factor 1	0.999
MDC1	mediator of DNA-damage checkpoint 1	0.999	Human
WRN	Werner syndrome, RecQ helicase-like	0.998
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.998	Yeast
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.997	Human Yeast
BRCA2	breast cancer 2, early onset	0.997
EGFR	epidermal growth factor receptor	0.996
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.995
CCNE1	cyclin E1	0.995	Fly
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.995
MAPK14	mitogen-activated protein kinase 14	0.994
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.993	Yeast
EP300	E1A binding protein p300	0.993
TOPBP1	topoisomerase (DNA) II binding protein 1	0.992
ATM	ataxia telangiectasia mutated	0.991
RBBP8	retinoblastoma binding protein 8	0.991
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.990	Fly
FANCA	Fanconi anemia, complementation group A	0.990
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.990	Human
RAD1	RAD1 homolog (S. pombe)	0.989
XIAP	X-linked inhibitor of apoptosis	0.987
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.987
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.987	Human
HIST1H3D	histone cluster 1, H3d	0.986	Human Yeast
PML	promyelocytic leukemia	0.986
RAD18	RAD18 homolog (S. cerevisiae)	0.985	Mouse
UBC	ubiquitin C	0.985
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.984
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.984	Human
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.984
CCND1	cyclin D1	0.983
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.982
NCOA3	nuclear receptor coactivator 3	0.982
DDB1	damage-specific DNA binding protein 1, 127kDa	0.982
RPA3	replication protein A3, 14kDa	0.981
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.981	Mouse
DTL	denticleless homolog (Drosophila)	0.981
ATR	ataxia telangiectasia and Rad3 related	0.980
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.979
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.979	Fly
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.978	Yeast
CDK4	cyclin-dependent kinase 4	0.977
BCL2L1	BCL2-like 1	0.977
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.977	Fly
HIST1H2BF	histone cluster 1, H2bf	0.977	Yeast
RAD51C	RAD51 homolog C (S. cerevisiae)	0.976
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.973
CCND3	cyclin D3	0.973	Human
PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	0.973
CHUK	conserved helix-loop-helix ubiquitous kinase	0.970	Human
MCM2	minichromosome maintenance complex component 2	0.970	Yeast
TERF2	telomeric repeat binding factor 2	0.969
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.969	Human
HIST1H2BD	histone cluster 1, H2bd	0.966	Yeast
TOP1	topoisomerase (DNA) I	0.964
SMC1A	structural maintenance of chromosomes 1A	0.964
SIRT1	sirtuin 1	0.961
HIST1H1C	histone cluster 1, H1c	0.960
HIST1H2BG	histone cluster 1, H2bg	0.960	Yeast
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.960
TFDP1	transcription factor Dp-1	0.959	Fly
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.957
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.955
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.954	Fly
STK4	serine/threonine kinase 4	0.953
SUMO2	SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)	0.952
SMC6	structural maintenance of chromosomes 6	0.950	Yeast Fly
FEN1	flap structure-specific endonuclease 1	0.950	Yeast Mouse
BCL2	B-cell CLL/lymphoma 2	0.949
RPA2	replication protein A2, 32kDa	0.947
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.947
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.946
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.945	Yeast
VIM	vimentin	0.945
HDAC2	histone deacetylase 2	0.939
MLH1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	0.938
BRCC3	BRCA1/BRCA2-containing complex, subunit 3	0.937
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.935	Human Mouse
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.935	Human Yeast
C19orf39	chromosome 19 open reading frame 39	0.933
DAXX	death-domain associated protein	0.932
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.926
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.922
BARD1	BRCA1 associated RING domain 1	0.921	Human
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.918	Fly
RBL1	retinoblastoma-like 1 (p107)	0.918	Fly
UBE3A	ubiquitin protein ligase E3A	0.917
ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.917	Human
SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)	0.917
PLK1	polo-like kinase 1	0.910
FANCL	Fanconi anemia, complementation group L	0.909
THOC4	THO complex 4	0.909
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	0.908
HIST1H2BH	histone cluster 1, H2bh	0.907	Yeast
ATRX	alpha thalassemia/mental retardation syndrome X-linked	0.907	Mouse
SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5	0.907	Mouse
IGF1R	insulin-like growth factor 1 receptor	0.906	Fly
GINS2	GINS complex subunit 2 (Psf2 homolog)	0.905	Yeast
GSK3B	glycogen synthase kinase 3 beta	0.905
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.904	Fly
HIST1H2BE	histone cluster 1, H2be	0.904	Yeast
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.904	Fly
HIST1H2BI	histone cluster 1, H2bi	0.904	Yeast
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.903
FGFR2	fibroblast growth factor receptor 2	0.903
TP53BP1	tumor protein p53 binding protein 1	0.896
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.895
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.894	Worm
CASP8AP2	caspase 8 associated protein 2	0.892
ATXN1	ataxin 1	0.891
EXO1	exonuclease 1	0.889
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.888
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.887
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.883
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.883
MCM7	minichromosome maintenance complex component 7	0.879
HIST1H2AC	histone cluster 1, H2ac	0.877	Human Yeast
XRCC1	X-ray repair complementing defective repair in Chinese hamster cells 1	0.872	Mouse Rat
MEN1	multiple endocrine neoplasia I	0.872
HIST1H2AE	histone cluster 1, H2ae	0.870	Human Yeast
SFN	stratifin	0.866
TK1	thymidine kinase 1, soluble	0.864
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.864
RUVBL1	RuvB-like 1 (E. coli)	0.859
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.858	Yeast Fly
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.857
CUL4A	cullin 4A	0.856	Human Mouse
SMAD4	SMAD family member 4	0.852
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	0.851	Fly
COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.850	Fly
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.845
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.844	Fly
PKM2	pyruvate kinase, muscle	0.836
CDK6	cyclin-dependent kinase 6	0.835
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.832
POLA1	polymerase (DNA directed), alpha 1, catalytic subunit	0.832
RFC2	replication factor C (activator 1) 2, 40kDa	0.830
FANCD2	Fanconi anemia, complementation group D2	0.829	Mouse
CLSPN	claspin	0.829
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.826
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.824
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.822	Human Fly
MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	0.817	Fly
ERCC8	excision repair cross-complementing rodent repair deficiency, complementation group 8	0.817
FGFR1	fibroblast growth factor receptor 1	0.815
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.815
MCM5	minichromosome maintenance complex component 5	0.813	Yeast
POLE2	polymerase (DNA directed), epsilon 2 (p59 subunit)	0.810	Yeast
ARIH2	ariadne homolog 2 (Drosophila)	0.809
HIST2H3C	histone cluster 2, H3c	0.806	Yeast
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.805
HDGF	hepatoma-derived growth factor	0.803
CREB1	cAMP responsive element binding protein 1	0.803
POLE3	polymerase (DNA directed), epsilon 3 (p17 subunit)	0.799	Yeast Fly
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.798	Human Fly
POLD3	polymerase (DNA-directed), delta 3, accessory subunit	0.797
GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa	0.788
CUX1	cut-like homeobox 1	0.785
RFC4	replication factor C (activator 1) 4, 37kDa	0.783
HIPK2	homeodomain interacting protein kinase 2	0.783
HIST1H2BK	histone cluster 1, H2bk	0.783	Yeast
HIST2H2BE	histone cluster 2, H2be	0.781	Yeast
BAX	BCL2-associated X protein	0.779	Human Mouse
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.777	Human
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.776
ESR1	estrogen receptor 1	0.773
MED1	mediator complex subunit 1	0.771
AR	androgen receptor	0.769
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.765
CCNE2	cyclin E2	0.765	Fly
STK3	serine/threonine kinase 3	0.763
THOC2	THO complex 2	0.762
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.758
NMI	N-myc (and STAT) interactor	0.757
MCM3	minichromosome maintenance complex component 3	0.750	Yeast Fly
CDCA4	cell division cycle associated 4	0.750
HIST1H2AJ	histone cluster 1, H2aj	0.749	Human Yeast
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.744
SETD7	SET domain containing (lysine methyltransferase) 7	0.739
SMC3	structural maintenance of chromosomes 3	0.735	Yeast
KAT2B	K(lysine) acetyltransferase 2B	0.735
PSEN2	presenilin 2 (Alzheimer disease 4)	0.732
MCM6	minichromosome maintenance complex component 6	0.732	Yeast
RAD51L3	RAD51-like 3 (S. cerevisiae)	0.730
CSNK1A1	casein kinase 1, alpha 1	0.730	Yeast Fly
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.727	Human Mouse
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.725	Fly
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	0.720	Fly
SMEK1	SMEK homolog 1, suppressor of mek1 (Dictyostelium)	0.714
NCBP1	nuclear cap binding protein subunit 1, 80kDa	0.714
SSRP1	structure specific recognition protein 1	0.712
PALB2	partner and localizer of BRCA2	0.710
RBBP4	retinoblastoma binding protein 4	0.708
APTX	aprataxin	0.707
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.705	Fly
RYBP	RING1 and YY1 binding protein	0.701
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.698
PSMB4	proteasome (prosome, macropain) subunit, beta type, 4	0.698
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.692
MSH3	mutS homolog 3 (E. coli)	0.691
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.691
XRCC4	X-ray repair complementing defective repair in Chinese hamster cells 4	0.690
CCNA2	cyclin A2	0.688
PAXIP1	PAX interacting (with transcription-activation domain) protein 1	0.685
HIST1H2BC	histone cluster 1, H2bc	0.683	Yeast
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.681	Fly
E2F4	E2F transcription factor 4, p107/p130-binding	0.681	Human
VEGFA	vascular endothelial growth factor A	0.678
HIST2H2AA4	histone cluster 2, H2aa4	0.672	Human
UIMC1	ubiquitin interaction motif containing 1	0.671
FAM175A	family with sequence similarity 175, member A	0.668
SMAD7	SMAD family member 7	0.663
ARID1A	AT rich interactive domain 1A (SWI-like)	0.662
PSMB3	proteasome (prosome, macropain) subunit, beta type, 3	0.657	Fly
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.657
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.655
MMS22L	MMS22-like, DNA repair protein	0.653
CXXC1	CXXC finger protein 1	0.651
ARRB1	arrestin, beta 1	0.651
RBBP7	retinoblastoma binding protein 7	0.649
SMAD2	SMAD family member 2	0.649
BIRC2	baculoviral IAP repeat containing 2	0.647	Human
CDT1	chromatin licensing and DNA replication factor 1	0.640
SKP2	S-phase kinase-associated protein 2 (p45)	0.640
REV1	REV1 homolog (S. cerevisiae)	0.639	Yeast Mouse Fly
SYK	spleen tyrosine kinase	0.637
COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	0.635
EGR1	early growth response 1	0.635
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.629
HTT	huntingtin	0.628
TFDP2	transcription factor Dp-2 (E2F dimerization partner 2)	0.627	Fly
PNKP	polynucleotide kinase 3'-phosphatase	0.627
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.626
RAD23B	RAD23 homolog B (S. cerevisiae)	0.626
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.625
RAD21	RAD21 homolog (S. pombe)	0.620
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.618
MAPK8	mitogen-activated protein kinase 8	0.617	Human
NCOA2	nuclear receptor coactivator 2	0.615
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.614
FGF1	fibroblast growth factor 1 (acidic)	0.614	Human
SP1	Sp1 transcription factor	0.611
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	0.610
TDG	thymine-DNA glycosylase	0.609
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.604	Fly
VHL	von Hippel-Lindau tumor suppressor	0.601
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.600
NUDT1	nudix (nucleoside diphosphate linked moiety X)-type motif 1	0.599
FANCM	Fanconi anemia, complementation group M	0.597
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.595
E2F2	E2F transcription factor 2	0.591	Human
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.590	Yeast Fly
NCOR1	nuclear receptor corepressor 1	0.589
ENO1	enolase 1, (alpha)	0.589
RFC5	replication factor C (activator 1) 5, 36.5kDa	0.589
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.588
YY1	YY1 transcription factor	0.588
HIST1H2AI	histone cluster 1, H2ai	0.582	Human Yeast
USP42	ubiquitin specific peptidase 42	0.581	Human
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.577
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.577
JUN	jun proto-oncogene	0.575	Human
MYST1	MYST histone acetyltransferase 1	0.572	Human Fly
COPS3	COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)	0.572	Fly
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.571
RAD9A	RAD9 homolog A (S. pombe)	0.569
MAPK1	mitogen-activated protein kinase 1	0.568	Human Mouse Fly
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.568
BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	0.563
CUL2	cullin 2	0.562
RFWD2	ring finger and WD repeat domain 2	0.555
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.551
TDP1	tyrosyl-DNA phosphodiesterase 1	0.550
PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.542
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.541	Yeast
TSC1	tuberous sclerosis 1	0.541
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.539
PSIP1	PC4 and SFRS1 interacting protein 1	0.538
VAV1	vav 1 guanine nucleotide exchange factor	0.536	Human
MATR3	matrin 3	0.533
PIAS4	protein inhibitor of activated STAT, 4	0.533	Mouse Worm Fly
ARRB2	arrestin, beta 2	0.531
RAD51L1	RAD51-like 1 (S. cerevisiae)	0.531
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.531
BCL3	B-cell CLL/lymphoma 3	0.529
FAS	Fas (TNF receptor superfamily, member 6)	0.527
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.526
MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	0.521
POLD2	polymerase (DNA directed), delta 2, regulatory subunit 50kDa	0.520	Fly
TWIST1	twist homolog 1 (Drosophila)	0.520
EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	0.517
IER3	immediate early response 3	0.514
TMPO	thymopoietin	0.514
HIST1H4A	histone cluster 1, H4a	0.514	Human Yeast
EIF3A	eukaryotic translation initiation factor 3, subunit A	0.513
EIF4A3	eukaryotic translation initiation factor 4A3	0.511	Fly
CHD4	chromodomain helicase DNA binding protein 4	0.509
TNRC6B	trinucleotide repeat containing 6B	0.507
HNRNPAB	heterogeneous nuclear ribonucleoprotein A/B	0.506
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.505
TRIM33	tripartite motif containing 33	0.504	Human
PRMT1	protein arginine methyltransferase 1	0.503
HIST1H2AM	histone cluster 1, H2am	0.503
XPC	xeroderma pigmentosum, complementation group C	0.500
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.500	Human
PSMD10	proteasome (prosome, macropain) 26S subunit, non-ATPase, 10	0.497
HUWE1	HECT, UBA and WWE domain containing 1	0.494
FOXM1	forkhead box M1	0.490
GINS1	GINS complex subunit 1 (Psf1 homolog)	0.487	Yeast
LRDD	leucine-rich repeats and death domain containing	0.487
NLRC4	NLR family, CARD domain containing 4	0.487
MUS81	MUS81 endonuclease homolog (S. cerevisiae)	0.486
APP	amyloid beta (A4) precursor protein	0.482
STAT1	signal transducer and activator of transcription 1, 91kDa	0.481
SOCS3	suppressor of cytokine signaling 3	0.480
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.479
TCF12	transcription factor 12	0.474	Fly
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.473
PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	0.467
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.466	Fly
ATF3	activating transcription factor 3	0.466
TAL1	T-cell acute lymphocytic leukemia 1	0.466	Human
HIST1H4F	histone cluster 1, H4f	0.464
PAX3	paired box 3	0.463
AHR	aryl hydrocarbon receptor	0.452
RUNX1	runt-related transcription factor 1	0.451
PABPC1	poly(A) binding protein, cytoplasmic 1	0.448
E2F3	E2F transcription factor 3	0.447	Human
TMSB4X	thymosin beta 4, X-linked	0.447
APITD1	apoptosis-inducing, TAF9-like domain 1	0.446
RCC1	regulator of chromosome condensation 1	0.445
HIST2H2AC	histone cluster 2, H2ac	0.445	Human Yeast
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.445
CCDC6	coiled-coil domain containing 6	0.444
SMAD3	SMAD family member 3	0.444
HIST1H4H	histone cluster 1, H4h	0.442
CBX5	chromobox homolog 5	0.441
RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	0.440	Human Fly
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.440
POLH	polymerase (DNA directed), eta	0.440
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.439	Human
HSPB1	heat shock 27kDa protein 1	0.438
RMI1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)	0.433
EME1	essential meiotic endonuclease 1 homolog 1 (S. pombe)	0.432
ERCC3	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)	0.431
THOC5	THO complex 5	0.429
ACTL6A	actin-like 6A	0.429
PTPRC	protein tyrosine phosphatase, receptor type, C	0.428
PLCG1	phospholipase C, gamma 1	0.426
HIST1H2AL	histone cluster 1, H2al	0.424	Human Yeast
NEDD8	neural precursor cell expressed, developmentally down-regulated 8	0.424
CHD8	chromodomain helicase DNA binding protein 8	0.421
BABAM1	BRISC and BRCA1 A complex member 1	0.420
MRFAP1	Morf4 family associated protein 1	0.418
RNF20	ring finger protein 20	0.418
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.418	Human Yeast
TXN	thioredoxin	0.416
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.412
TIMELESS	timeless homolog (Drosophila)	0.409	Mouse
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.408
NCF1	neutrophil cytosolic factor 1	0.406
SNAI1	snail homolog 1 (Drosophila)	0.404
ZMYM2	zinc finger, MYM-type 2	0.403
PPHLN1	periphilin 1	0.400
TNFSF14	tumor necrosis factor (ligand) superfamily, member 14	0.399
APAF1	apoptotic peptidase activating factor 1	0.399
RAD23A	RAD23 homolog A (S. cerevisiae)	0.398
U2AF2	U2 small nuclear RNA auxiliary factor 2	0.398
CDC45	cell division cycle 45 homolog (S. cerevisiae)	0.398	Yeast Fly
CCND2	cyclin D2	0.396	Human
RBPMS	RNA binding protein with multiple splicing	0.395
LAT	linker for activation of T cells	0.394
SCAF8	SR-related CTD-associated factor 8	0.393
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.392
MYH7B	myosin, heavy chain 7B, cardiac muscle, beta	0.392
TRIP13	thyroid hormone receptor interactor 13	0.389	Mouse
FYN	FYN oncogene related to SRC, FGR, YES	0.385
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.382
CCNC	cyclin C	0.381	Fly
HIST1H3A	histone cluster 1, H3a	0.377	Yeast
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.376
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.374	Fly
MTA1	metastasis associated 1	0.374
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.371
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.371
SNW1	SNW domain containing 1	0.370
MAPK3	mitogen-activated protein kinase 3	0.370
CUL4B	cullin 4B	0.369
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.368	Human
FANCG	Fanconi anemia, complementation group G	0.367
HIST1H3H	histone cluster 1, H3h	0.365	Yeast
HIST1H2BM	histone cluster 1, H2bm	0.364	Yeast
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.364
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.363
INO80	INO80 homolog (S. cerevisiae)	0.363
TP53BP2	tumor protein p53 binding protein, 2	0.363
PARP14	poly (ADP-ribose) polymerase family, member 14	0.362	Human
BCL6	B-cell CLL/lymphoma 6	0.362
POLE	polymerase (DNA directed), epsilon	0.360
CASP2	caspase 2, apoptosis-related cysteine peptidase	0.359
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.356
BID	BH3 interacting domain death agonist	0.356
IRF1	interferon regulatory factor 1	0.355
TTI1	Tel2 interacting protein 1 homolog (S. pombe)	0.355
PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	0.354
HIST1H3G	histone cluster 1, H3g	0.352
TPI1	triosephosphate isomerase 1	0.351
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.351
FANCI	Fanconi anemia, complementation group I	0.351
TUBGCP3	tubulin, gamma complex associated protein 3	0.350
PPIA	peptidylprolyl isomerase A (cyclophilin A)	0.350
UBXN7	UBX domain protein 7	0.346
POMP	proteasome maturation protein	0.346
TBK1	TANK-binding kinase 1	0.345	Human
KDM2A	lysine (K)-specific demethylase 2A	0.345
ERH	enhancer of rudimentary homolog (Drosophila)	0.343
CNOT1	CCR4-NOT transcription complex, subunit 1	0.341
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.341
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.340
BCAS2	breast carcinoma amplified sequence 2	0.339
TONSL	tonsoku-like, DNA repair protein	0.337
PRKCA	protein kinase C, alpha	0.336
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.336
RFC1	replication factor C (activator 1) 1, 145kDa	0.335	Yeast
OPTN	optineurin	0.335
MED13L	mediator complex subunit 13-like	0.334
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.334
REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)	0.333	Mouse
CAV1	caveolin 1, caveolae protein, 22kDa	0.332
UNG	uracil-DNA glycosylase	0.331	Worm
PMS1	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	0.330	Human Yeast Mouse
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.330	Fly
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.329
CD80	CD80 molecule	0.329
PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	0.328
SARNP	SAP domain containing ribonucleoprotein	0.326
RSF1	remodeling and spacing factor 1	0.326
DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)	0.326
MAP2K4	mitogen-activated protein kinase kinase 4	0.325
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.325
MORF4L1	mortality factor 4 like 1	0.324
HIST1H2BB	histone cluster 1, H2bb	0.323	Yeast
HIST1H2AG	histone cluster 1, H2ag	0.320	Human Yeast
COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.320	Fly
CFLAR	CASP8 and FADD-like apoptosis regulator	0.319
BTG1	B-cell translocation gene 1, anti-proliferative	0.316	Human
ETF1	eukaryotic translation termination factor 1	0.316
CYLD	cylindromatosis (turban tumor syndrome)	0.316
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.314
NSMCE4A	non-SMC element 4 homolog A (S. cerevisiae)	0.314
SNTA1	syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)	0.313
NCL	nucleolin	0.313
RBL2	retinoblastoma-like 2 (p130)	0.313	Fly
ZNF148	zinc finger protein 148	0.311
HIST1H4D	histone cluster 1, H4d	0.310
CDK7	cyclin-dependent kinase 7	0.310
DDB2	damage-specific DNA binding protein 2, 48kDa	0.310
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.303
FKBP3	FK506 binding protein 3, 25kDa	0.303
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.302
LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)	0.302
ARHGDIB	Rho GDP dissociation inhibitor (GDI) beta	0.302
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.301	Yeast
RAD54B	RAD54 homolog B (S. cerevisiae)	0.297
RAD17	RAD17 homolog (S. pombe)	0.296
LMNB1	lamin B1	0.294
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.292
SF3B1	splicing factor 3b, subunit 1, 155kDa	0.292
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.292	Fly
DUT	deoxyuridine triphosphatase	0.291
NCF2	neutrophil cytosolic factor 2	0.288
DNA2	DNA replication helicase 2 homolog (yeast)	0.288
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.288	Fly
LRP1	low density lipoprotein receptor-related protein 1	0.288
HIST1H2AB	histone cluster 1, H2ab	0.288	Human Yeast
CIAO1	cytosolic iron-sulfur protein assembly 1	0.286
MED13	mediator complex subunit 13	0.286
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.286
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.284
TUBB	tubulin, beta	0.283
AURKA	aurora kinase A	0.283
HIST1H2BJ	histone cluster 1, H2bj	0.283	Yeast
PSME4	proteasome (prosome, macropain) activator subunit 4	0.283	Mouse
WDHD1	WD repeat and HMG-box DNA binding protein 1	0.282
PRNP	prion protein	0.282
GFER	growth factor, augmenter of liver regeneration	0.282
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.280
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.279	Human Fly
MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	0.279	Yeast
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.278
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.277
HDAC3	histone deacetylase 3	0.276
SIVA1	SIVA1, apoptosis-inducing factor	0.276
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.276
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.274
ORC1	origin recognition complex, subunit 1	0.274
ANKRD17	ankyrin repeat domain 17	0.272
SETD8	SET domain containing (lysine methyltransferase) 8	0.271
BIRC3	baculoviral IAP repeat containing 3	0.271	Human
HIST1H4B	histone cluster 1, H4b	0.269
PGK1	phosphoglycerate kinase 1	0.266
COPS7A	COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)	0.265	Fly
TP73	tumor protein p73	0.265
POU3F2	POU class 3 homeobox 2	0.264
VPS72	vacuolar protein sorting 72 homolog (S. cerevisiae)	0.264
EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	0.263
GRB10	growth factor receptor-bound protein 10	0.263
RNF11	ring finger protein 11	0.262
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.260
ARHGAP1	Rho GTPase activating protein 1	0.259
EIF4G1	eukaryotic translation initiation factor 4 gamma, 1	0.258
KIF5B	kinesin family member 5B	0.257
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.255
CPSF2	cleavage and polyadenylation specific factor 2, 100kDa	0.254
PDS5A	PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)	0.254
GRB7	growth factor receptor-bound protein 7	0.254
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.253	Mouse
FANCB	Fanconi anemia, complementation group B	0.253
XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	0.253
CASP6	caspase 6, apoptosis-related cysteine peptidase	0.253	Human
PURA	purine-rich element binding protein A	0.252
HAUS1	HAUS augmin-like complex, subunit 1	0.252
MAPK6	mitogen-activated protein kinase 6	0.252
VPRBP	Vpr (HIV-1) binding protein	0.251
MYOD1	myogenic differentiation 1	0.250
MCM4	minichromosome maintenance complex component 4	0.250	Yeast
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.250
H3F3C	H3 histone, family 3C	0.250
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.249
MAGEA2	melanoma antigen family A, 2	0.249
CNOT3	CCR4-NOT transcription complex, subunit 3	0.249
RRM1	ribonucleotide reductase M1	0.248
PRMT2	protein arginine methyltransferase 2	0.248
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.247
SENP1	SUMO1/sentrin specific peptidase 1	0.246
BAD	BCL2-associated agonist of cell death	0.243
NCOA6	nuclear receptor coactivator 6	0.242
SOS1	son of sevenless homolog 1 (Drosophila)	0.240
NSMCE2	non-SMC element 2, MMS21 homolog (S. cerevisiae)	0.240
HIST1H2BO	histone cluster 1, H2bo	0.239	Yeast
ARID4A	AT rich interactive domain 4A (RBP1-like)	0.238
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.238
PIM1	pim-1 oncogene	0.237
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.237
NFYA	nuclear transcription factor Y, alpha	0.237
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.237
GAB1	GRB2-associated binding protein 1	0.236
RB1CC1	RB1-inducible coiled-coil 1	0.236
TRIM28	tripartite motif containing 28	0.235
HCFC1	host cell factor C1 (VP16-accessory protein)	0.235
PTK2	PTK2 protein tyrosine kinase 2	0.234
RANBP1	RAN binding protein 1	0.234
PPM1G	protein phosphatase, Mg2+/Mn2+ dependent, 1G	0.233
ZNRF1	zinc and ring finger 1	0.232
RHOXF2	Rhox homeobox family, member 2	0.231
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.231
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.230
CCL14	chemokine (C-C motif) ligand 14	0.229
FADD	Fas (TNFRSF6)-associated via death domain	0.229
ANXA1	annexin A1	0.228
CUL1	cullin 1	0.227	Fly
DCAF7	DDB1 and CUL4 associated factor 7	0.227
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.226	Fly
GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1	0.225
HBP1	HMG-box transcription factor 1	0.225
IRF3	interferon regulatory factor 3	0.224
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.224
CTCF	CCCTC-binding factor (zinc finger protein)	0.223
GSTCD	glutathione S-transferase, C-terminal domain containing	0.223
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.222	Human Fly
MTF2	metal response element binding transcription factor 2	0.221	Human
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.221
AATF	apoptosis antagonizing transcription factor	0.220
MTA2	metastasis associated 1 family, member 2	0.219	Human
RECQL4	RecQ protein-like 4	0.219
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.218	Human
EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	0.218
EFNA1	ephrin-A1	0.216
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.216
CDCA7	cell division cycle associated 7	0.215
ANKRD28	ankyrin repeat domain 28	0.214
HMGB2	high mobility group box 2	0.213
CDK8	cyclin-dependent kinase 8	0.213	Fly
RIF1	RAP1 interacting factor homolog (yeast)	0.212
HSPA14	heat shock 70kDa protein 14	0.212
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.210	Human
FOXO3	forkhead box O3	0.209	Mouse Fly
TRIM27	tripartite motif containing 27	0.209
CDK11B	cyclin-dependent kinase 11B	0.209
ING1	inhibitor of growth family, member 1	0.208	Human
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.208
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.208
RALY	RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))	0.207
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.207	Fly
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.207
TINF2	TERF1 (TRF1)-interacting nuclear factor 2	0.206
POLQ	polymerase (DNA directed), theta	0.206	Human Mouse Fly
XPO1	exportin 1 (CRM1 homolog, yeast)	0.206
ADRM1	adhesion regulating molecule 1	0.205
MBD3	methyl-CpG binding domain protein 3	0.205
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.204	Human
CNOT6	CCR4-NOT transcription complex, subunit 6	0.203
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.202	Human
ERBB2IP	erbb2 interacting protein	0.202
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.201
EIF4E	eukaryotic translation initiation factor 4E	0.200
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.200
LCK	lymphocyte-specific protein tyrosine kinase	0.199
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.198	Fly
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.198
HIST1H4E	histone cluster 1, H4e	0.197
BHLHE40	basic helix-loop-helix family, member e40	0.196
FBXO11	F-box protein 11	0.196
WAPAL	wings apart-like homolog (Drosophila)	0.195
RECQL	RecQ protein-like (DNA helicase Q1-like)	0.195
WWOX	WW domain containing oxidoreductase	0.195
ING2	inhibitor of growth family, member 2	0.194	Human
POLR2G	polymerase (RNA) II (DNA directed) polypeptide G	0.194
PIAS2	protein inhibitor of activated STAT, 2	0.193	Worm
SRSF10	serine/arginine-rich splicing factor 10	0.193
H2AFV	H2A histone family, member V	0.192	Fly
SOCS1	suppressor of cytokine signaling 1	0.191
TOP2B	topoisomerase (DNA) II beta 180kDa	0.191	Human Fly
SIRT2	sirtuin 2	0.191
KDM1A	lysine (K)-specific demethylase 1A	0.190
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.190	Human
WT1	Wilms tumor 1	0.190
MED21	mediator complex subunit 21	0.189
INTS7	integrator complex subunit 7	0.188
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.188	Fly
BRD7	bromodomain containing 7	0.188
SMC4	structural maintenance of chromosomes 4	0.187
ILF2	interleukin enhancer binding factor 2, 45kDa	0.187
ERCC4	excision repair cross-complementing rodent repair deficiency, complementation group 4	0.186
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.186
UBXN1	UBX domain protein 1	0.186
ACVR1B	activin A receptor, type IB	0.185
CARD11	caspase recruitment domain family, member 11	0.185
GINS4	GINS complex subunit 4 (Sld5 homolog)	0.184	Yeast
BOLA2B	bolA homolog 2B (E. coli)	0.184
HIST1H1E	histone cluster 1, H1e	0.183
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.183
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.183
PRIM2	primase, DNA, polypeptide 2 (58kDa)	0.183	Yeast
PPIE	peptidylprolyl isomerase E (cyclophilin E)	0.183
CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase	0.183
TMEM194A	transmembrane protein 194A	0.183
FYB	FYN binding protein	0.183
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.182
RASSF3	Ras association (RalGDS/AF-6) domain family member 3	0.182	Human
PDPK1	3-phosphoinositide dependent protein kinase-1	0.182	Fly
DCLRE1C	DNA cross-link repair 1C	0.182
MTA3	metastasis associated 1 family, member 3	0.182	Human
THOC6	THO complex 6 homolog (Drosophila)	0.181
TERT	telomerase reverse transcriptase	0.181
TRADD	TNFRSF1A-associated via death domain	0.181
CCHCR1	coiled-coil alpha-helical rod protein 1	0.181
TRAF6	TNF receptor-associated factor 6	0.180
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.180	Human
MSN	moesin	0.179
RNF168	ring finger protein 168	0.179
RAD54L	RAD54-like (S. cerevisiae)	0.179	Mouse Fly
CDCA5	cell division cycle associated 5	0.179
FOXO1	forkhead box O1	0.179	Mouse Worm Fly
HIST1H1D	histone cluster 1, H1d	0.178
CCNT1	cyclin T1	0.177
SF3B2	splicing factor 3b, subunit 2, 145kDa	0.176
ERCC1	excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)	0.176
HDAC4	histone deacetylase 4	0.176
SAV1	salvador homolog 1 (Drosophila)	0.176
BTRC	beta-transducin repeat containing	0.176
HELLS	helicase, lymphoid-specific	0.176
SIAH1	seven in absentia homolog 1 (Drosophila)	0.175
CHTOP	chromatin target of PRMT1	0.175
NCOA1	nuclear receptor coactivator 1	0.174
GPS1	G protein pathway suppressor 1	0.173	Fly
EIF3I	eukaryotic translation initiation factor 3, subunit I	0.172
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.171
ZNF746	zinc finger protein 746	0.171
RFWD3	ring finger and WD repeat domain 3	0.170
GMNN	geminin, DNA replication inhibitor	0.169
CD86	CD86 molecule	0.169
SMG1	SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)	0.168
NCOR2	nuclear receptor corepressor 2	0.166
PIAS3	protein inhibitor of activated STAT, 3	0.166	Fly
RAD51AP1	RAD51 associated protein 1	0.166
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.166
UBA1	ubiquitin-like modifier activating enzyme 1	0.164
YEATS4	YEATS domain containing 4	0.164
POLG2	polymerase (DNA directed), gamma 2, accessory subunit	0.164
WDR48	WD repeat domain 48	0.164	Mouse
C20orf94	chromosome 20 open reading frame 94	0.164
ATRIP	ATR interacting protein	0.164
RAD52	RAD52 homolog (S. cerevisiae)	0.163	Yeast
INO80E	INO80 complex subunit E	0.163
FBXW7	F-box and WD repeat domain containing 7	0.162
ZNF420	zinc finger protein 420	0.162
C12orf4	chromosome 12 open reading frame 4	0.162
XPA	xeroderma pigmentosum, complementation group A	0.162
CUL5	cullin 5	0.161
MYST2	MYST histone acetyltransferase 2	0.161	Human
MCMBP	minichromosome maintenance complex binding protein	0.160
TERF1	telomeric repeat binding factor (NIMA-interacting) 1	0.160	Human
CELF1	CUGBP, Elav-like family member 1	0.159
HERC2	hect domain and RLD 2	0.158
SH3RF1	SH3 domain containing ring finger 1	0.157
ZBTB7A	zinc finger and BTB domain containing 7A	0.157
SFPQ	splicing factor proline/glutamine-rich	0.157
CSE1L	CSE1 chromosome segregation 1-like (yeast)	0.156
BRWD1	bromodomain and WD repeat domain containing 1	0.156	Fly
PIH1D1	PIH1 domain containing 1	0.156
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.156
HMGB1	high mobility group box 1	0.156
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.156
HTATSF1	HIV-1 Tat specific factor 1	0.155
KDM4A	lysine (K)-specific demethylase 4A	0.155
SNRPA	small nuclear ribonucleoprotein polypeptide A	0.154
EIF3G	eukaryotic translation initiation factor 3, subunit G	0.154
MCRS1	microspherule protein 1	0.153
CCNH	cyclin H	0.153
VPS25	vacuolar protein sorting 25 homolog (S. cerevisiae)	0.153
ANAPC4	anaphase promoting complex subunit 4	0.153
NONO	non-POU domain containing, octamer-binding	0.153