IMP: Integrative Multi-species Prediction

Homo sapiens

88 genes annotated in human

bone disease

DOID:0080001

A connective tissue disease that affects the structure or development of bone or causes an impairment of normal bone function.

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Gene Predictions

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Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "bone disease" (in gray)

Name	Description	Probability	Func Analog Organism
BMPR1A	bone morphogenetic protein receptor, type IA	1.000	Human
COL1A1	collagen, type I, alpha 1	0.998
FGF1	fibroblast growth factor 1 (acidic)	0.997
HLA-DMA	major histocompatibility complex, class II, DM alpha	0.992
COL5A1	collagen, type V, alpha 1	0.983	Human
TJP1	tight junction protein 1 (zona occludens 1)	0.966
COL3A1	collagen, type III, alpha 1	0.921	Human
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.917
FGFR2	fibroblast growth factor receptor 2	0.892
COL6A1	collagen, type VI, alpha 1	0.873
PDIA3	protein disulfide isomerase family A, member 3	0.865
CHRD	chordin	0.834
FSTL1	follistatin-like 1	0.830
COL6A2	collagen, type VI, alpha 2	0.829
BMP2	bone morphogenetic protein 2	0.818
PDIA4	protein disulfide isomerase family A, member 4	0.811
FLNA	filamin A, alpha	0.807	Human
BMPR1B	bone morphogenetic protein receptor, type IB	0.795
SMAD1	SMAD family member 1	0.782
DDR2	discoidin domain receptor tyrosine kinase 2	0.766
LOX	lysyl oxidase	0.763
COL1A2	collagen, type I, alpha 2	0.761
CD247	CD247 molecule	0.718
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.695
COL4A1	collagen, type IV, alpha 1	0.695
FGF10	fibroblast growth factor 10	0.691
PSEN1	presenilin 1	0.688
GDF5	growth differentiation factor 5	0.655
P4HB	prolyl 4-hydroxylase, beta polypeptide	0.599
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.580
COL2A1	collagen, type II, alpha 1	0.554
SETD8	SET domain containing (lysine methyltransferase) 8	0.550
FGF2	fibroblast growth factor 2 (basic)	0.547
BGN	biglycan	0.523
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.490
KRT8	keratin 8	0.486
COL4A2	collagen, type IV, alpha 2	0.471
HR	hairless homolog (mouse)	0.469
COL5A2	collagen, type V, alpha 2	0.468	Human
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.452
BMP7	bone morphogenetic protein 7	0.414	Human
ENG	endoglin	0.382
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.372	Human
TROAP	trophinin associated protein (tastin)	0.366
SPARC	secreted protein, acidic, cysteine-rich (osteonectin)	0.356
RPN1	ribophorin I	0.354
SMAD3	SMAD family member 3	0.350
BBS10	Bardet-Biedl syndrome 10	0.347
DDOST	dolichyl-diphosphooligosaccharide--protein glycosyltransferase	0.343
FN1	fibronectin 1	0.341
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.340
CRELD2	cysteine-rich with EGF-like domains 2	0.338
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.330
SH2D1A	SH2 domain containing 1A	0.324
RARA	retinoic acid receptor, alpha	0.323
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.308
COL11A1	collagen, type XI, alpha 1	0.302	Human
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.287
CLEC18C	C-type lectin domain family 18, member C	0.286
TGFBR1	transforming growth factor, beta receptor 1	0.280	Human
RUNX1	runt-related transcription factor 1	0.272	Human
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.270
MRC2	mannose receptor, C type 2	0.270
MFAP2	microfibrillar-associated protein 2	0.268
CNTF	ciliary neurotrophic factor	0.265
SMAD4	SMAD family member 4	0.263
PSEN2	presenilin 2 (Alzheimer disease 4)	0.260
IL10RA	interleukin 10 receptor, alpha	0.258
PCOLCE	procollagen C-endopeptidase enhancer	0.257
RXRA	retinoid X receptor, alpha	0.246
C1orf93	chromosome 1 open reading frame 93	0.244
MSX1	msh homeobox 1	0.243	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.235	Human
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.233
HLA-DRA	major histocompatibility complex, class II, DR alpha	0.229
HSPG2	heparan sulfate proteoglycan 2	0.217
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.213
FKBP10	FK506 binding protein 10, 65 kDa	0.212
C19orf10	chromosome 19 open reading frame 10	0.202
FBLN2	fibulin 2	0.200
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.196
NOSTRIN	nitric oxide synthase trafficker	0.182
COL7A1	collagen, type VII, alpha 1	0.181
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.181
FBLIM1	filamin binding LIM protein 1	0.177
PDIA5	protein disulfide isomerase family A, member 5	0.177
IGFBP3	insulin-like growth factor binding protein 3	0.174
NID1	nidogen 1	0.171
LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	0.164
FGFR1	fibroblast growth factor receptor 1	0.162
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.161
C16orf59	chromosome 16 open reading frame 59	0.160
NOG	noggin	0.158
SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)	0.157
KDELR2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2	0.154
FGFR3	fibroblast growth factor receptor 3	0.151
FGF7	fibroblast growth factor 7	0.151
C2orf18	chromosome 2 open reading frame 18	0.149
AKAP10	A kinase (PRKA) anchor protein 10	0.149
HLA-DRB4	major histocompatibility complex, class II, DR beta 4	0.148
PXDN	peroxidasin homolog (Drosophila)	0.147
EMP3	epithelial membrane protein 3	0.144
NRP1	neuropilin 1	0.144
MXRA5	matrix-remodelling associated 5	0.142
CAPRIN2	caprin family member 2	0.140
COL18A1	collagen, type XVIII, alpha 1	0.137
FRS2	fibroblast growth factor receptor substrate 2	0.137
RBPMS	RNA binding protein with multiple splicing	0.135
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.133
KIAA1377	KIAA1377	0.132
ADAM12	ADAM metallopeptidase domain 12	0.126
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.125
SKIL	SKI-like oncogene	0.125	Human
PKP4	plakophilin 4	0.125
WISP1	WNT1 inducible signaling pathway protein 1	0.120
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.120
E2F2	E2F transcription factor 2	0.119
GANAB	glucosidase, alpha; neutral AB	0.118
CSPG4	chondroitin sulfate proteoglycan 4	0.118
PLXND1	plexin D1	0.117
THY1	Thy-1 cell surface antigen	0.113
HLA-DMB	major histocompatibility complex, class II, DM beta	0.111
HLA-A	major histocompatibility complex, class I, A	0.107
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.106
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.106
POSTN	periostin, osteoblast specific factor	0.106
AEBP1	AE binding protein 1	0.101
SUFU	suppressor of fused homolog (Drosophila)	0.101
RHOXF2	Rhox homeobox family, member 2	0.101
GLT25D1	glycosyltransferase 25 domain containing 1	0.099
DLX5	distal-less homeobox 5	0.099
COL8A2	collagen, type VIII, alpha 2	0.099	Human
CKAP4	cytoskeleton-associated protein 4	0.098
NELL2	NEL-like 2 (chicken)	0.098
INHBA	inhibin, beta A	0.097
NID2	nidogen 2 (osteonidogen)	0.096
NBR1	neighbor of BRCA1 gene 1	0.096
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.095
GABARAPL1	GABA(A) receptor-associated protein like 1	0.094
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.092	Human
FKBP2	FK506 binding protein 2, 13kDa	0.092
TRAM2	translocation associated membrane protein 2	0.092
LEPREL4	leprecan-like 4	0.092
BID	BH3 interacting domain death agonist	0.090
EMILIN1	elastin microfibril interfacer 1	0.089
NCOA6	nuclear receptor coactivator 6	0.089
TGFB3	transforming growth factor, beta 3	0.088
COMP	cartilage oligomeric matrix protein	0.087
PDGFA	platelet-derived growth factor alpha polypeptide	0.087
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.087
MANF	mesencephalic astrocyte-derived neurotrophic factor	0.087
STK36	serine/threonine kinase 36	0.086
CALR	calreticulin	0.086
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.085
SSR4	signal sequence receptor, delta (translocon-associated protein delta)	0.084
THBS2	thrombospondin 2	0.083	Human
ZFYVE9	zinc finger, FYVE domain containing 9	0.082
COL5A3	collagen, type V, alpha 3	0.082	Human
UNC5B	unc-5 homolog B (C. elegans)	0.081
HYOU1	hypoxia up-regulated 1	0.081
ZMYND11	zinc finger, MYND-type containing 11	0.080
TNC	tenascin C	0.079
MSX2	msh homeobox 2	0.078
ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)	0.077
TMED9	transmembrane emp24 protein transport domain containing 9	0.077
COPG	coatomer protein complex, subunit gamma	0.077
GLI2	GLI family zinc finger 2	0.076	Human
HLA-C	major histocompatibility complex, class I, C	0.076
FNDC1	fibronectin type III domain containing 1	0.076
TRAF5	TNF receptor-associated factor 5	0.075
ERO1L	ERO1-like (S. cerevisiae)	0.075
ACAN	aggrecan	0.073
PDE4DIP	phosphodiesterase 4D interacting protein	0.071
ITGB4	integrin, beta 4	0.071
COL16A1	collagen, type XVI, alpha 1	0.070	Human
GNS	glucosamine (N-acetyl)-6-sulfatase	0.069
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.069
KDELR3	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3	0.069
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.068
LMO4	LIM domain only 4	0.067
DIP2A	DIP2 disco-interacting protein 2 homolog A (Drosophila)	0.067
BCL2L1	BCL2-like 1	0.066
THBS1	thrombospondin 1	0.066	Human
CCL7	chemokine (C-C motif) ligand 7	0.066
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.064	Human
SSR2	signal sequence receptor, beta (translocon-associated protein beta)	0.064
FAM64A	family with sequence similarity 64, member A	0.064
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.064
CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	0.062
HAP1	huntingtin-associated protein 1	0.062
ECE1	endothelin converting enzyme 1	0.062
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.061
CDK6	cyclin-dependent kinase 6	0.061
TGFB2	transforming growth factor, beta 2	0.061	Human
FOXF2	forkhead box F2	0.059
RBM11	RNA binding motif protein 11	0.059
STC1	stanniocalcin 1	0.058
RADIL	Ras association and DIL domains	0.058
SMAD2	SMAD family member 2	0.058
BMP8A	bone morphogenetic protein 8a	0.058	Human
GLG1	golgi glycoprotein 1	0.058
EXT1	exostosin 1	0.057
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.057	Human
TMED3	transmembrane emp24 protein transport domain containing 3	0.057
TSPAN4	tetraspanin 4	0.057
RRBP1	ribosome binding protein 1 homolog 180kDa (dog)	0.057
OCLN	occludin	0.056
PDIA6	protein disulfide isomerase family A, member 6	0.056
SOX11	SRY (sex determining region Y)-box 11	0.055	Human
LBX1	ladybird homeobox 1	0.055
ACTN4	actinin, alpha 4	0.055
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.054
LGALS1	lectin, galactoside-binding, soluble, 1	0.054
BAG3	BCL2-associated athanogene 3	0.054
LEPREL2	leprecan-like 2	0.054	Human
MBTPS1	membrane-bound transcription factor peptidase, site 1	0.054
CD84	CD84 molecule	0.053	Human
PTHLH	parathyroid hormone-like hormone	0.053
MSN	moesin	0.053
VMP1	vacuole membrane protein 1	0.053
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.053
WWTR1	WW domain containing transcription regulator 1	0.052
EFEMP2	EGF containing fibulin-like extracellular matrix protein 2	0.052
RUNX2	runt-related transcription factor 2	0.052
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.052
SPHK1	sphingosine kinase 1	0.052
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.052
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.051
P4HA2	prolyl 4-hydroxylase, alpha polypeptide II	0.051
HOXA11	homeobox A11	0.051
HYAL1	hyaluronoglucosaminidase 1	0.051
USP42	ubiquitin specific peptidase 42	0.051
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.051
SDF2L1	stromal cell-derived factor 2-like 1	0.051
PRRX2	paired related homeobox 2	0.050
COL10A1	collagen, type X, alpha 1	0.050
LAMB2	laminin, beta 2 (laminin S)	0.050
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.050
FOXD1	forkhead box D1	0.050
XRCC3	X-ray repair complementing defective repair in Chinese hamster cells 3	0.050
SND1	staphylococcal nuclease and tudor domain containing 1	0.049
PLTP	phospholipid transfer protein	0.049
LMF2	lipase maturation factor 2	0.049
MXRA8	matrix-remodelling associated 8	0.049
EHD2	EH-domain containing 2	0.048
FAM46D	family with sequence similarity 46, member D	0.048
IRF9	interferon regulatory factor 9	0.048
COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)	0.048
TAL1	T-cell acute lymphocytic leukemia 1	0.048	Human
RPN2	ribophorin II	0.048
PAQR4	progestin and adipoQ receptor family member IV	0.047
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.047
COL9A3	collagen, type IX, alpha 3	0.047	Human
TYK2	tyrosine kinase 2	0.047
EPHB3	EPH receptor B3	0.047
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.047
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.047
WT1	Wilms tumor 1	0.047
WNT2	wingless-type MMTV integration site family member 2	0.046	Human
LIG4	ligase IV, DNA, ATP-dependent	0.046
CRLF1	cytokine receptor-like factor 1	0.046
GJD3	gap junction protein, delta 3, 31.9kDa	0.046
RNF31	ring finger protein 31	0.046
STAT2	signal transducer and activator of transcription 2, 113kDa	0.046
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.046
CHTF18	CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)	0.045
CRABP2	cellular retinoic acid binding protein 2	0.045
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.045
GPC1	glypican 1	0.045
LRRC15	leucine rich repeat containing 15	0.044
TJP2	tight junction protein 2 (zona occludens 2)	0.044
HMGA2	high mobility group AT-hook 2	0.044
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.044
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.043	Human
ERO1LB	ERO1-like beta (S. cerevisiae)	0.043
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.043
DLX4	distal-less homeobox 4	0.043
B2M	beta-2-microglobulin	0.043
NTM	neurotrimin	0.043
PTK7	PTK7 protein tyrosine kinase 7	0.042
CLDN7	claudin 7	0.042
SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)	0.042
NCSTN	nicastrin	0.042
CLASRP	CLK4-associating serine/arginine rich protein	0.042
FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)	0.041
EDEM2	ER degradation enhancer, mannosidase alpha-like 2	0.041
SFRP2	secreted frizzled-related protein 2	0.041
RCN1	reticulocalbin 1, EF-hand calcium binding domain	0.041
NKX3-2	NK3 homeobox 2	0.041
ZBED1	zinc finger, BED-type containing 1	0.041
C9orf140	chromosome 9 open reading frame 140	0.041
DOCK9	dedicator of cytokinesis 9	0.041
SHB	Src homology 2 domain containing adaptor protein B	0.041
FOXC1	forkhead box C1	0.041
LAMB3	laminin, beta 3	0.041
C5orf22	chromosome 5 open reading frame 22	0.040
GDF6	growth differentiation factor 6	0.040	Human
DTX2	deltex homolog 2 (Drosophila)	0.040
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.040
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.040
SFRP4	secreted frizzled-related protein 4	0.040
SOAT1	sterol O-acyltransferase 1	0.040
TWIST1	twist homolog 1 (Drosophila)	0.040
IFT88	intraflagellar transport 88 homolog (Chlamydomonas)	0.040
SNRNP35	small nuclear ribonucleoprotein 35kDa (U11/U12)	0.040
FEV	FEV (ETS oncogene family)	0.040
HOXD11	homeobox D11	0.040
EPAS1	endothelial PAS domain protein 1	0.040
ZEB2	zinc finger E-box binding homeobox 2	0.039
VSX1	visual system homeobox 1	0.039
SLC38A7	solute carrier family 38, member 7	0.039
SHOX2	short stature homeobox 2	0.039
HOXB13	homeobox B13	0.039	Human
EFHC1	EF-hand domain (C-terminal) containing 1	0.039
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.039
C14orf80	chromosome 14 open reading frame 80	0.039
ZNF431	zinc finger protein 431	0.039
MTMR4	myotubularin related protein 4	0.039
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.039
HAS2	hyaluronan synthase 2	0.039
NKD2	naked cuticle homolog 2 (Drosophila)	0.039
FAP	fibroblast activation protein, alpha	0.039
MFSD1	major facilitator superfamily domain containing 1	0.038
LAMA5	laminin, alpha 5	0.038
LOXL1	lysyl oxidase-like 1	0.038
HOXD9	homeobox D9	0.038
TNR	tenascin R (restrictin, janusin)	0.038
GALNT2	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)	0.038
EPHB2	EPH receptor B2	0.038
IL11	interleukin 11	0.037
CCDC17	coiled-coil domain containing 17	0.037
GPR161	G protein-coupled receptor 161	0.037
NCAPH2	non-SMC condensin II complex, subunit H2	0.037
PDLIM4	PDZ and LIM domain 4	0.037
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.037
PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	0.037	Human
FGF3	fibroblast growth factor 3	0.037
LAMB1	laminin, beta 1	0.037
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.037
LUM	lumican	0.037
CARHSP1	calcium regulated heat stable protein 1, 24kDa	0.037
GLI3	GLI family zinc finger 3	0.037
HS2ST1	heparan sulfate 2-O-sulfotransferase 1	0.037
PYCR1	pyrroline-5-carboxylate reductase 1	0.036
ARTN	artemin	0.036
TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b	0.036	Human
CALU	calumenin	0.036
KAL1	Kallmann syndrome 1 sequence	0.036
TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)	0.036
RHOD	ras homolog gene family, member D	0.036
VASN	vasorin	0.036
NEU4	sialidase 4	0.036
TGFBR3	transforming growth factor, beta receptor III	0.035
ACVR1	activin A receptor, type I	0.035	Human
C7orf42	chromosome 7 open reading frame 42	0.035
C3orf64	chromosome 3 open reading frame 64	0.035
DEDD	death effector domain containing	0.035
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.035
NAGA	N-acetylgalactosaminidase, alpha-	0.035
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.035
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.035
MAG	myelin associated glycoprotein	0.035
WNT5A	wingless-type MMTV integration site family, member 5A	0.035	Human
MIF	macrophage migration inhibitory factor (glycosylation-inhibiting factor)	0.035
COL4A5	collagen, type IV, alpha 5	0.035
FST	follistatin	0.035
BMP4	bone morphogenetic protein 4	0.034	Human
ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	0.034
CAPZA2	capping protein (actin filament) muscle Z-line, alpha 2	0.034
OPTN	optineurin	0.034
FBXO21	F-box protein 21	0.034
SRI	sorcin	0.034
EN1	engrailed homeobox 1	0.034
LOXL2	lysyl oxidase-like 2	0.034
NFATC4	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4	0.034
BMP1	bone morphogenetic protein 1	0.034
OLFML2B	olfactomedin-like 2B	0.034
LAP3	leucine aminopeptidase 3	0.034
SPRY2	sprouty homolog 2 (Drosophila)	0.034
PAX5	paired box 5	0.034
ANTXR2	anthrax toxin receptor 2	0.034
GAS1	growth arrest-specific 1	0.034
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.034
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.034
PRPH	peripherin	0.033
CCND3	cyclin D3	0.033
LMNA	lamin A/C	0.033
KRT16	keratin 16	0.033
GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	0.033
PTGER1	prostaglandin E receptor 1 (subtype EP1), 42kDa	0.033
MVP	major vault protein	0.033
CHPF2	chondroitin polymerizing factor 2	0.033
TPBG	trophoblast glycoprotein	0.033
ING2	inhibitor of growth family, member 2	0.033
COL12A1	collagen, type XII, alpha 1	0.032
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.032
FGF8	fibroblast growth factor 8 (androgen-induced)	0.032
HM13	histocompatibility (minor) 13	0.032
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.032
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.032	Human
CDK14	cyclin-dependent kinase 14	0.032
MAPK8	mitogen-activated protein kinase 8	0.032
CREB3L1	cAMP responsive element binding protein 3-like 1	0.032
BDKRB1	bradykinin receptor B1	0.032
KRT75	keratin 75	0.032
IFNGR1	interferon gamma receptor 1	0.032
NPTX2	neuronal pentraxin II	0.032
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.032
ACTN1	actinin, alpha 1	0.032
ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	0.032
ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	0.032
COL6A3	collagen, type VI, alpha 3	0.032
SETD7	SET domain containing (lysine methyltransferase) 7	0.031
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.031
RAB3IL1	RAB3A interacting protein (rabin3)-like 1	0.031
CALCA	calcitonin-related polypeptide alpha	0.031
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.031
OAF	OAF homolog (Drosophila)	0.031
HOXA9	homeobox A9	0.031
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.031
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.031
HOXD8	homeobox D8	0.031
CD248	CD248 molecule, endosialin	0.031
C17orf53	chromosome 17 open reading frame 53	0.031
MGAT1	mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase	0.031
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.031
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.031
CD81	CD81 molecule	0.031
PDGFRL	platelet-derived growth factor receptor-like	0.031
MMP10	matrix metallopeptidase 10 (stromelysin 2)	0.031	Human
JAK2	Janus kinase 2	0.031
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.031
EFR3A	EFR3 homolog A (S. cerevisiae)	0.031
EPYC	epiphycan	0.030
NMT2	N-myristoyltransferase 2	0.030
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.030
CDR2L	cerebellar degeneration-related protein 2-like	0.030
IRF4	interferon regulatory factor 4	0.030
ODZ4	odz, odd Oz/ten-m homolog 4 (Drosophila)	0.030
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.030
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.030
SOX9	SRY (sex determining region Y)-box 9	0.030
FOSL1	FOS-like antigen 1	0.030
CHGB	chromogranin B (secretogranin 1)	0.029
LHX2	LIM homeobox 2	0.029
FBN1	fibrillin 1	0.029
BNC1	basonuclin 1	0.029
TMTC3	transmembrane and tetratricopeptide repeat containing 3	0.029
FOXO3	forkhead box O3	0.029
CA12	carbonic anhydrase XII	0.029
VAX2	ventral anterior homeobox 2	0.029
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.029
ANXA6	annexin A6	0.029
PPARA	peroxisome proliferator-activated receptor alpha	0.029	Human
DOCK7	dedicator of cytokinesis 7	0.029
MMP13	matrix metallopeptidase 13 (collagenase 3)	0.029
CCND1	cyclin D1	0.029
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.029	Human
THBS3	thrombospondin 3	0.029	Human
MAX	MYC associated factor X	0.029
PTPRF	protein tyrosine phosphatase, receptor type, F	0.029
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.029
DLX3	distal-less homeobox 3	0.029
SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)	0.029
CHPF	chondroitin polymerizing factor	0.029
EFNB3	ephrin-B3	0.029
GEM	GTP binding protein overexpressed in skeletal muscle	0.029
CLCF1	cardiotrophin-like cytokine factor 1	0.029
CTHRC1	collagen triple helix repeat containing 1	0.029
POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa	0.029
CCNA1	cyclin A1	0.029
PVR	poliovirus receptor	0.029
ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	0.029
IRX5	iroquois homeobox 5	0.029
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.029
SERTAD1	SERTA domain containing 1	0.029
CUL9	cullin 9	0.029
ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	0.029
PRDM4	PR domain containing 4	0.029
VCAN	versican	0.029	Human
PRSS23	protease, serine, 23	0.028
NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1	0.028
SNAI2	snail homolog 2 (Drosophila)	0.028
WNT9B	wingless-type MMTV integration site family, member 9B	0.028	Human
GALR2	galanin receptor 2	0.028
KRT14	keratin 14	0.028
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.028
SDC1	syndecan 1	0.028
CLCNKB	chloride channel Kb	0.028
NPY2R	neuropeptide Y receptor Y2	0.028
BDKRB2	bradykinin receptor B2	0.028
PAM	peptidylglycine alpha-amidating monooxygenase	0.028
PRAME	preferentially expressed antigen in melanoma	0.028
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.028
GLT8D2	glycosyltransferase 8 domain containing 2	0.028
MNX1	motor neuron and pancreas homeobox 1	0.028
ELF4	E74-like factor 4 (ets domain transcription factor)	0.028
TLX1	T-cell leukemia homeobox 1	0.028
SOX2	SRY (sex determining region Y)-box 2	0.028	Human
PLXDC1	plexin domain containing 1	0.028
MMP8	matrix metallopeptidase 8 (neutrophil collagenase)	0.028	Human
CSNK1D	casein kinase 1, delta	0.028
CCNO	cyclin O	0.028
PITX2	paired-like homeodomain 2	0.028	Human
ECEL1	endothelin converting enzyme-like 1	0.028
FZD8	frizzled homolog 8 (Drosophila)	0.028
WNT11	wingless-type MMTV integration site family, member 11	0.028	Human
SCARF2	scavenger receptor class F, member 2	0.028
COL9A1	collagen, type IX, alpha 1	0.028
AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)	0.028
HES6	hairy and enhancer of split 6 (Drosophila)	0.028	Human
RRN3	RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)	0.028
DOCK8	dedicator of cytokinesis 8	0.027
FOXE3	forkhead box E3	0.027
SIL1	SIL1 homolog, endoplasmic reticulum chaperone (S. cerevisiae)	0.027
PPIC	peptidylprolyl isomerase C (cyclophilin C)	0.027	Human
IL4	interleukin 4	0.027
IRX4	iroquois homeobox 4	0.027
SLC38A6	solute carrier family 38, member 6	0.027
C2orf88	chromosome 2 open reading frame 88	0.027
IFNB1	interferon, beta 1, fibroblast	0.027
SCO2	SCO cytochrome oxidase deficient homolog 2 (yeast)	0.027
ISLR	immunoglobulin superfamily containing leucine-rich repeat	0.027
IL24	interleukin 24	0.027	Human
TBC1D1	TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1	0.027
TMEM158	transmembrane protein 158 (gene/pseudogene)	0.027
COL9A2	collagen, type IX, alpha 2	0.027
HOXC11	homeobox C11	0.027
ARSI	arylsulfatase family, member I	0.027
OSMR	oncostatin M receptor	0.027
ATG2A	ATG2 autophagy related 2 homolog A (S. cerevisiae)	0.027
HAND2	heart and neural crest derivatives expressed 2	0.027	Human
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.027
SMO	smoothened homolog (Drosophila)	0.027
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.027
OLIG2	oligodendrocyte lineage transcription factor 2	0.027
WIF1	WNT inhibitory factor 1	0.027
FGF4	fibroblast growth factor 4	0.027
CXXC5	CXXC finger protein 5	0.027
OCA2	oculocutaneous albinism II	0.027
PFDN1	prefoldin subunit 1	0.027
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.027
SIX2	SIX homeobox 2	0.027
SLC38A10	solute carrier family 38, member 10	0.026
GAL	galanin prepropeptide	0.026
KDELR1	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1	0.026
PHLDA2	pleckstrin homology-like domain, family A, member 2	0.026
CYP24A1	cytochrome P450, family 24, subfamily A, polypeptide 1	0.026	Human
FZD7	frizzled homolog 7 (Drosophila)	0.026
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.026
HIVEP3	human immunodeficiency virus type I enhancer binding protein 3	0.026
GPX7	glutathione peroxidase 7	0.026
USH1G	Usher syndrome 1G (autosomal recessive)	0.026
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.026
HOXD1	homeobox D1	0.026
RHOU	ras homolog gene family, member U	0.026
IL17A	interleukin 17A	0.026
ABHD3	abhydrolase domain containing 3	0.026
ALX1	ALX homeobox 1	0.026
INHBB	inhibin, beta B	0.026
GXYLT2	glucoside xylosyltransferase 2	0.026
MED25	mediator complex subunit 25	0.026
PTRF	polymerase I and transcript release factor	0.026
FOXF1	forkhead box F1	0.026
MFGE8	milk fat globule-EGF factor 8 protein	0.026
FAM103A1	family with sequence similarity 103, member A1	0.026
SMAD5	SMAD family member 5	0.026
MN1	meningioma (disrupted in balanced translocation) 1	0.026
EOMES	eomesodermin	0.026
E2F1	E2F transcription factor 1	0.026
EDEM3	ER degradation enhancer, mannosidase alpha-like 3	0.026
DUSP4	dual specificity phosphatase 4	0.026
FAM83G	family with sequence similarity 83, member G	0.026
WNT5B	wingless-type MMTV integration site family, member 5B	0.026	Human
DUSP9	dual specificity phosphatase 9	0.026
APH1A	anterior pharynx defective 1 homolog A (C. elegans)	0.026
MFAP3	microfibrillar-associated protein 3	0.026
LRP5	low density lipoprotein receptor-related protein 5	0.026
TLX3	T-cell leukemia homeobox 3	0.026
PAQR3	progestin and adipoQ receptor family member III	0.026
KAT2B	K(lysine) acetyltransferase 2B	0.025
CD70	CD70 molecule	0.025
AP1S2	adaptor-related protein complex 1, sigma 2 subunit	0.025
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.025
NRTN	neurturin	0.025
SLX1B	SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)	0.025
RARG	retinoic acid receptor, gamma	0.025
HMGXB3	HMG box domain containing 3	0.025
CNPY3	canopy 3 homolog (zebrafish)	0.025
ALPL	alkaline phosphatase, liver/bone/kidney	0.025
PAX2	paired box 2	0.025
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.025
PRSS21	protease, serine, 21 (testisin)	0.025
ITGB7	integrin, beta 7	0.025
FOXQ1	forkhead box Q1	0.025
BNC2	basonuclin 2	0.025
TACSTD2	tumor-associated calcium signal transducer 2	0.025
PAX6	paired box 6	0.025
RABL3	RAB, member of RAS oncogene family-like 3	0.025
ANPEP	alanyl (membrane) aminopeptidase	0.025
HOXA5	homeobox A5	0.025
MATN3	matrilin 3	0.025
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.025
TG	thyroglobulin	0.025
ABTB1	ankyrin repeat and BTB (POZ) domain containing 1	0.025
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.025
S100A3	S100 calcium binding protein A3	0.025
DENND3	DENN/MADD domain containing 3	0.025
ABHD13	abhydrolase domain containing 13	0.025
A1BG	alpha-1-B glycoprotein	0.025
C14orf129	chromosome 14 open reading frame 129	0.025
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.025
PLXNA1	plexin A1	0.025
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.025
FBN2	fibrillin 2	0.025
PLCG1	phospholipase C, gamma 1	0.025
PLAGL1	pleiomorphic adenoma gene-like 1	0.025
BARX1	BARX homeobox 1	0.025
CCND2	cyclin D2	0.025
APBA1	amyloid beta (A4) precursor protein-binding, family A, member 1	0.025
MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2	0.025
CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)	0.025
SIX3	SIX homeobox 3	0.025
COL14A1	collagen, type XIV, alpha 1	0.025
NKX6-2	NK6 homeobox 2	0.025
CHIT1	chitinase 1 (chitotriosidase)	0.025
CILP2	cartilage intermediate layer protein 2	0.025
BARX2	BARX homeobox 2	0.025
UBD	ubiquitin D	0.025
WNT3	wingless-type MMTV integration site family, member 3	0.024	Human
F3	coagulation factor III (thromboplastin, tissue factor)	0.024
HOXD10	homeobox D10	0.024
PRRX1	paired related homeobox 1	0.024
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.024
THRA	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)	0.024
KIAA1199	KIAA1199	0.024
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.024
RAD54L	RAD54-like (S. cerevisiae)	0.024
MDK	midkine (neurite growth-promoting factor 2)	0.024
PDPN	podoplanin	0.024
SH3PXD2A	SH3 and PX domains 2A	0.024
AZI1	5-azacytidine induced 1	0.024
C17orf70	chromosome 17 open reading frame 70	0.024
SIX1	SIX homeobox 1	0.024
PITX1	paired-like homeodomain 1	0.024
LHFP	lipoma HMGIC fusion partner	0.024
FOXG1	forkhead box G1	0.024
CD97	CD97 molecule	0.024
WNT1	wingless-type MMTV integration site family, member 1	0.024
NOX4	NADPH oxidase 4	0.024
HSD17B3	hydroxysteroid (17-beta) dehydrogenase 3	0.024
GPX8	glutathione peroxidase 8 (putative)	0.024
ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1	0.024
HTRA1	HtrA serine peptidase 1	0.024
TMEM214	transmembrane protein 214	0.024
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.024
RAD52	RAD52 homolog (S. cerevisiae)	0.024
CST4	cystatin S	0.024
SPON2	spondin 2, extracellular matrix protein	0.024
HSPB8	heat shock 22kDa protein 8	0.024
LTK	leukocyte receptor tyrosine kinase	0.024
CSRP2	cysteine and glycine-rich protein 2	0.024
ZBTB32	zinc finger and BTB domain containing 32	0.024
BTN2A2	butyrophilin, subfamily 2, member A2	0.024
ACO1	aconitase 1, soluble	0.024
SMAD6	SMAD family member 6	0.024
SGPP1	sphingosine-1-phosphate phosphatase 1	0.024
CRABP1	cellular retinoic acid binding protein 1	0.024
COPZ2	coatomer protein complex, subunit zeta 2	0.024
SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.024
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.024
AQP5	aquaporin 5	0.024
KAZALD1	Kazal-type serine peptidase inhibitor domain 1	0.024
APOB	apolipoprotein B (including Ag(x) antigen)	0.023
PDCD7	programmed cell death 7	0.023
AP1AR	adaptor-related protein complex 1 associated regulatory protein	0.023
SOX10	SRY (sex determining region Y)-box 10	0.023	Human
GDNF	glial cell derived neurotrophic factor	0.023
ISG15	ISG15 ubiquitin-like modifier	0.023
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.023
FGFR4	fibroblast growth factor receptor 4	0.023	Human
HPDL	4-hydroxyphenylpyruvate dioxygenase-like	0.023
HAPLN1	hyaluronan and proteoglycan link protein 1	0.023	Human
SLC6A9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	0.023
SLC19A2	solute carrier family 19 (thiamine transporter), member 2	0.023
LIPG	lipase, endothelial	0.023
NAV3	neuron navigator 3	0.023
ENC1	ectodermal-neural cortex 1 (with BTB-like domain)	0.023
HLA-F	major histocompatibility complex, class I, F	0.023
HOXC13	homeobox C13	0.023	Human
MIA	melanoma inhibitory activity	0.023
MEAF6	MYST/Esa1-associated factor 6	0.023
PAX1	paired box 1	0.023
CYP19A1	cytochrome P450, family 19, subfamily A, polypeptide 1	0.023
ANGPTL2	angiopoietin-like 2	0.023
SIM2	single-minded homolog 2 (Drosophila)	0.023
WSB2	WD repeat and SOCS box containing 2	0.023
HOXA13	homeobox A13	0.023	Human
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.023
FZD2	frizzled homolog 2 (Drosophila)	0.023
IGFBP2	insulin-like growth factor binding protein 2, 36kDa	0.023
SDC4	syndecan 4	0.023
TCHH	trichohyalin	0.023
MAGED2	melanoma antigen family D, 2	0.023
UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1	0.023
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.023
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.023
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.023
CUX1	cut-like homeobox 1	0.023
UBXN2A	UBX domain protein 2A	0.023
BICC1	bicaudal C homolog 1 (Drosophila)	0.023
TMBIM4	transmembrane BAX inhibitor motif containing 4	0.023
TBX3	T-box 3	0.023
PAX9	paired box 9	0.023
ESM1	endothelial cell-specific molecule 1	0.023
CRTAM	cytotoxic and regulatory T cell molecule	0.023
ETV4	ets variant 4	0.023
MAGT1	magnesium transporter 1	0.023
GCA	grancalcin, EF-hand calcium binding protein	0.023
FOXH1	forkhead box H1	0.023
ZMIZ1	zinc finger, MIZ-type containing 1	0.023
SCARB1	scavenger receptor class B, member 1	0.023
CALCR	calcitonin receptor	0.023
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.023
DACH1	dachshund homolog 1 (Drosophila)	0.023
HOXC6	homeobox C6	0.022
KCTD15	potassium channel tetramerisation domain containing 15	0.022
ULK1	unc-51-like kinase 1 (C. elegans)	0.022
PAEP	progestagen-associated endometrial protein	0.022
CDK2AP2	cyclin-dependent kinase 2 associated protein 2	0.022
RAB34	RAB34, member RAS oncogene family	0.022
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.022
NTSR1	neurotensin receptor 1 (high affinity)	0.022
ANGPT4	angiopoietin 4	0.022
POU4F2	POU class 4 homeobox 2	0.022
C7orf64	chromosome 7 open reading frame 64	0.022
LTBR	lymphotoxin beta receptor (TNFR superfamily, member 3)	0.022	Human
ECM1	extracellular matrix protein 1	0.022
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	0.022
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.022
FOXL2	forkhead box L2	0.022
ARID3C	AT rich interactive domain 3C (BRIGHT-like)	0.022
EXT2	exostosin 2	0.022
SP1	Sp1 transcription factor	0.022
STBD1	starch binding domain 1	0.022
PURA	purine-rich element binding protein A	0.022
GPR64	G protein-coupled receptor 64	0.022
P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2	0.022
BACE2	beta-site APP-cleaving enzyme 2	0.022
KIAA1033	KIAA1033	0.022