IMP: Integrative Multi-species Prediction

Homo sapiens

12 genes annotated in human

organ growth

The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.

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In addition to gene-name show these genes:

Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "organ growth"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "organ growth" (in gray)

Name	Description	Probability	Func Analog Organism
RARA	retinoic acid receptor, alpha	0.953	Mouse
FGFR2	fibroblast growth factor receptor 2	0.941	Mouse
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.756
INSR	insulin receptor	0.649	Fly
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.466	Mouse Fly
TBX5	T-box 5	0.441
FGF1	fibroblast growth factor 1 (acidic)	0.388	Human
TSC2	tuberous sclerosis 2	0.376	Fly
TGFB1	transforming growth factor, beta 1	0.306	Human
EGFR	epidermal growth factor receptor	0.282
STK3	serine/threonine kinase 3	0.277	Mouse
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.259
CREBBP	CREB binding protein	0.239
RASSF5	Ras association (RalGDS/AF-6) domain family member 5	0.230
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.212	Mouse
SMAD3	SMAD family member 3	0.206
FGFR1	fibroblast growth factor receptor 1	0.202	Mouse
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.193
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.180
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.179
GRB10	growth factor receptor-bound protein 10	0.178
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.175
YAP1	Yes-associated protein 1	0.174	Mouse
CHD8	chromodomain helicase DNA binding protein 8	0.172	Fly
EP300	E1A binding protein p300	0.139
STK4	serine/threonine kinase 4	0.139	Mouse
PRKCZ	protein kinase C, zeta	0.130
BCL2L1	BCL2-like 1	0.108
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.097	Mouse Rat
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.092	Fly
FGF10	fibroblast growth factor 10	0.090
NCOA1	nuclear receptor coactivator 1	0.069
TP53BP2	tumor protein p53 binding protein, 2	0.067
NCOR1	nuclear receptor corepressor 1	0.066
SMAD2	SMAD family member 2	0.064	Mouse
NCOR2	nuclear receptor corepressor 2	0.062
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.060
APP	amyloid beta (A4) precursor protein	0.058
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.054
SCHIP1	schwannomin interacting protein 1	0.053
YY1	YY1 transcription factor	0.053
JUB	jub, ajuba homolog (Xenopus laevis)	0.047	Fly
CHD7	chromodomain helicase DNA binding protein 7	0.045	Fly
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.044
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.043
NOTCH1	notch 1	0.041	Mouse
BAD	BCL2-associated agonist of cell death	0.039
WDR5	WD repeat domain 5	0.034
HIPK3	homeodomain interacting protein kinase 3	0.034	Fly
IGF1R	insulin-like growth factor 1 receptor	0.034	Fly
TTR	transthyretin	0.033
JAG1	jagged 1	0.032
HDAC1	histone deacetylase 1	0.032
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.031	Fly
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.030
ENG	endoglin	0.029
BAX	BCL2-associated X protein	0.029
TSC1	tuberous sclerosis 1	0.028	Fly
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.028
SKIL	SKI-like oncogene	0.027
SNAI1	snail homolog 1 (Drosophila)	0.026
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.026
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.026
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.025
GAB2	GRB2-associated binding protein 2	0.024
GAB1	GRB2-associated binding protein 1	0.024
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.023
RBPJ	recombination signal binding protein for immunoglobulin kappa J region	0.023	Mouse
IRS1	insulin receptor substrate 1	0.022	Fly
HNF4A	hepatocyte nuclear factor 4, alpha	0.021
NOTCH3	notch 3	0.021
FGF2	fibroblast growth factor 2 (basic)	0.021
MED25	mediator complex subunit 25	0.021
THBS1	thrombospondin 1	0.020	Mouse
LIMD1	LIM domains containing 1	0.019	Fly
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.019
BCL2	B-cell CLL/lymphoma 2	0.019	Mouse
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.019
SPOP	speckle-type POZ protein	0.018
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.018
ARHGEF40	Rho guanine nucleotide exchange factor (GEF) 40	0.017
FRS2	fibroblast growth factor receptor substrate 2	0.017
GATA4	GATA binding protein 4	0.017	Mouse Rat
PPARA	peroxisome proliferator-activated receptor alpha	0.016
NRIP1	nuclear receptor interacting protein 1	0.016
COL11A2	collagen, type XI, alpha 2	0.016
FKBP8	FK506 binding protein 8, 38kDa	0.015
TGFB3	transforming growth factor, beta 3	0.015
PDPK1	3-phosphoinositide dependent protein kinase-1	0.015	Fly
CSNK1E	casein kinase 1, epsilon	0.015	Fly
HDAC4	histone deacetylase 4	0.015
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.014
ARNT	aryl hydrocarbon receptor nuclear translocator	0.014
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.014
WT1	Wilms tumor 1	0.013	Mouse
FSTL1	follistatin-like 1	0.013
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.013
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.013
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.013
MAPK1	mitogen-activated protein kinase 1	0.013
KLF4	Kruppel-like factor 4 (gut)	0.013
HIC1	hypermethylated in cancer 1	0.013
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.013
NCOA3	nuclear receptor coactivator 3	0.013
SATB2	SATB homeobox 2	0.013
QKI	quaking homolog, KH domain RNA binding (mouse)	0.013
TGFBR1	transforming growth factor, beta receptor 1	0.013
LAT	linker for activation of T cells	0.013
MAPK9	mitogen-activated protein kinase 9	0.013
PRRC2B	proline-rich coiled-coil 2B	0.012
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.012
ESR1	estrogen receptor 1	0.012	Mouse
CCL14	chemokine (C-C motif) ligand 14	0.012
FGF8	fibroblast growth factor 8 (androgen-induced)	0.012
MAML1	mastermind-like 1 (Drosophila)	0.012
FGF7	fibroblast growth factor 7	0.012
RBBP5	retinoblastoma binding protein 5	0.012
ZEB2	zinc finger E-box binding homeobox 2	0.012
AMOTL2	angiomotin like 2	0.012
SMAD6	SMAD family member 6	0.011
MEF2A	myocyte enhancer factor 2A	0.011
TCF12	transcription factor 12	0.011
NUMB	numb homolog (Drosophila)	0.011
CGB5	chorionic gonadotropin, beta polypeptide 5	0.011
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.011
BAK1	BCL2-antagonist/killer 1	0.011
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.010
RERE	arginine-glutamic acid dipeptide (RE) repeats	0.010
WWOX	WW domain containing oxidoreductase	0.010
SAV1	salvador homolog 1 (Drosophila)	0.010	Mouse