IMP
Process View
negative regulation of metaphase anaphase transition of cell cycle
Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of metaphase anaphase transition of cell cycle"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.734 | ||
| CDK2 | cyclin-dependent kinase 2 | 0.638 | ||
| BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.536 | Fly | |
| MDC1 | mediator of DNA-damage checkpoint 1 | 0.421 | ||
| CCNA2 | cyclin A2 | 0.334 | ||
| ANAPC7 | anaphase promoting complex subunit 7 | 0.314 | ||
| CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 0.300 | Yeast | |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.285 | ||
| BUB3 | budding uninhibited by benzimidazoles 3 homolog (yeast) | 0.238 | Worm Fly | |
| CCNB1 | cyclin B1 | 0.145 | ||
| BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.131 | Fly | |
| ANAPC4 | anaphase promoting complex subunit 4 | 0.078 | ||
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.074 | ||
| SKA1 | spindle and kinetochore associated complex subunit 1 | 0.064 | ||
| BRCA2 | breast cancer 2, early onset | 0.059 | ||
| NDC80 | NDC80 homolog, kinetochore complex component (S. cerevisiae) | 0.057 | ||
| FBXO5 | F-box protein 5 | 0.052 | ||
| SKP2 | S-phase kinase-associated protein 2 (p45) | 0.049 | ||
| UHRF1 | ubiquitin-like with PHD and ring finger domains 1 | 0.049 | ||
| SPC24 | SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.040 | ||
| SKA3 | spindle and kinetochore associated complex subunit 3 | 0.039 | ||
| ZNF207 | zinc finger protein 207 | 0.036 | ||
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.033 | ||
| ANAPC11 | anaphase promoting complex subunit 11 | 0.033 | ||
| MRE11A | MRE11 meiotic recombination 11 homolog A (S. cerevisiae) | 0.030 | ||
| CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.030 | ||
| CBX5 | chromobox homolog 5 | 0.027 | ||
| DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.026 | ||
| TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.026 | ||
| SMC3 | structural maintenance of chromosomes 3 | 0.025 | ||
| C13orf34 | chromosome 13 open reading frame 34 | 0.024 | ||
| CASC5 | cancer susceptibility candidate 5 | 0.023 | ||
| UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.023 | ||
| SKA2 | spindle and kinetochore associated complex subunit 2 | 0.022 | ||
| PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.022 | ||
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme | 0.022 | ||
| AURKB | aurora kinase B | 0.022 | ||
| TP53BP1 | tumor protein p53 binding protein 1 | 0.022 | ||
| ATMIN | ATM interactor | 0.021 | ||
| CCNE1 | cyclin E1 | 0.021 | Fly | |
| KIF18A | kinesin family member 18A | 0.021 | ||
| FXR2 | fragile X mental retardation, autosomal homolog 2 | 0.019 | ||
| TERF2IP | telomeric repeat binding factor 2, interacting protein | 0.019 | ||
| MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.019 | ||
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.018 | ||
| CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.018 | ||
| MYST1 | MYST histone acetyltransferase 1 | 0.018 | ||
| HERC2 | hect domain and RLD 2 | 0.018 | ||
| MAD2L1BP | MAD2L1 binding protein | 0.018 | ||
| UBE2C | ubiquitin-conjugating enzyme E2C | 0.017 | ||
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.017 | ||
| PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.017 | ||
| NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.017 | ||
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.017 | ||
| PPME1 | protein phosphatase methylesterase 1 | 0.016 | ||
| RB1 | retinoblastoma 1 | 0.016 | ||
| INCENP | inner centromere protein antigens 135/155kDa | 0.016 | ||
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.016 | ||
| CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.015 | ||
| PPP6R2 | protein phosphatase 6, regulatory subunit 2 | 0.015 | ||
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.015 | ||
| CDT1 | chromatin licensing and DNA replication factor 1 | 0.015 | ||
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.015 | ||
| HIST1H4A | histone cluster 1, H4a | 0.014 | ||
| CCND1 | cyclin D1 | 0.014 | ||
| SMC4 | structural maintenance of chromosomes 4 | 0.014 | ||
| RAD52 | RAD52 homolog (S. cerevisiae) | 0.014 | ||
| CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.014 | ||
| SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.013 | ||
| CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.013 | ||
| PRC1 | protein regulator of cytokinesis 1 | 0.013 | ||
| KDM4A | lysine (K)-specific demethylase 4A | 0.013 | ||
| PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.013 | ||
| RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.013 | ||
| BRCA1 | breast cancer 1, early onset | 0.013 | ||
| CCNB2 | cyclin B2 | 0.013 | ||
| PAXIP1 | PAX interacting (with transcription-activation domain) protein 1 | 0.012 | ||
| CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.012 | ||
| CENPE | centromere protein E, 312kDa | 0.012 | Mouse | |
| PRNP | prion protein | 0.012 | ||
| HIST1H4F | histone cluster 1, H4f | 0.012 | ||
| NUF2 | NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae) | 0.012 | ||
| RAD51L1 | RAD51-like 1 (S. cerevisiae) | 0.012 | ||
| PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.011 | ||
| SGOL1 | shugoshin-like 1 (S. pombe) | 0.011 | ||
| ANKRD52 | ankyrin repeat domain 52 | 0.011 | ||
| PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.011 | ||
| ERCC6L | excision repair cross-complementing rodent repair deficiency, complementation group 6-like | 0.011 | ||
| ZSWIM7 | zinc finger, SWIM-type containing 7 | 0.011 | ||
| HIST1H1E | histone cluster 1, H1e | 0.011 | ||
| PLK1 | polo-like kinase 1 | 0.010 | ||
| FANCD2 | Fanconi anemia, complementation group D2 | 0.010 | ||
| DCLRE1C | DNA cross-link repair 1C | 0.010 | ||
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.010 | ||
| HIST1H1B | histone cluster 1, H1b | 0.010 | ||
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.010 | ||
| TTK | TTK protein kinase | 0.010 | Yeast | |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.010 |