IMP: Integrative Multi-species Prediction

Homo sapiens

325 genes annotated in human

protein catabolic process

The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein catabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "protein catabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
UBC	ubiquitin C	1.000	Worm
RNF11	ring finger protein 11	1.000
TP53	tumor protein p53	1.000
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	1.000
VCP	valosin containing protein	1.000
PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6	1.000
PSMD4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	1.000	Yeast Worm
CUL1	cullin 1	0.999
SKP1	S-phase kinase-associated protein 1	0.999
UBE2D2	ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)	0.998	Human Yeast
SQSTM1	sequestosome 1	0.998
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.998
PSMA1	proteasome (prosome, macropain) subunit, alpha type, 1	0.998	Yeast
PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2	0.998	Yeast
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.997
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.996
XIAP	X-linked inhibitor of apoptosis	0.995	Human
SNX9	sorting nexin 9	0.995
PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7	0.994	Yeast
CUL2	cullin 2	0.994	Mouse Worm
PSMB7	proteasome (prosome, macropain) subunit, beta type, 7	0.993	Yeast
BTRC	beta-transducin repeat containing	0.993
CREBBP	CREB binding protein	0.993
SMAD2	SMAD family member 2	0.993	Human
SMAD3	SMAD family member 3	0.992
RB1	retinoblastoma 1	0.991
PSMA5	proteasome (prosome, macropain) subunit, alpha type, 5	0.988	Yeast
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.987	Mouse
HSPA8	heat shock 70kDa protein 8	0.987
CUL3	cullin 3	0.986
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.985
PSMB4	proteasome (prosome, macropain) subunit, beta type, 4	0.985	Yeast
PSMD1	proteasome (prosome, macropain) 26S subunit, non-ATPase, 1	0.983	Yeast
PSMB2	proteasome (prosome, macropain) subunit, beta type, 2	0.983	Yeast
PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4	0.983	Yeast
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.982	Worm
PSMB6	proteasome (prosome, macropain) subunit, beta type, 6	0.980	Yeast
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.980	Yeast
RAD23A	RAD23 homolog A (S. cerevisiae)	0.979
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.978
TRAF1	TNF receptor-associated factor 1	0.977
TRAF6	TNF receptor-associated factor 6	0.976
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.976
PSMD14	proteasome (prosome, macropain) 26S subunit, non-ATPase, 14	0.974
ARIH2	ariadne homolog 2 (Drosophila)	0.973
PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3	0.971	Yeast
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.971
PSMD11	proteasome (prosome, macropain) 26S subunit, non-ATPase, 11	0.967
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.965
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.965
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.962	Yeast Mouse
FBXW11	F-box and WD repeat domain containing 11	0.962
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.961
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.959	Rat
UBQLN1	ubiquilin 1	0.954	Human
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.953	Worm
PSMB3	proteasome (prosome, macropain) subunit, beta type, 3	0.949	Yeast
POMP	proteasome maturation protein	0.947
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.946
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.944
GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	0.941	Mouse
RNF111	ring finger protein 111	0.936	Mouse
BIRC2	baculoviral IAP repeat containing 2	0.933
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.928
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.928
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.926	Fly
FASLG	Fas ligand (TNF superfamily, member 6)	0.914
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.906	Human
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.902	Worm
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.898
MAPK1	mitogen-activated protein kinase 1	0.898	Worm
DERL1	Der1-like domain family, member 1	0.896
PTK2	PTK2 protein tyrosine kinase 2	0.894	Human Mouse
PSMC2	proteasome (prosome, macropain) 26S subunit, ATPase, 2	0.893
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.893
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.871
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.870
HDAC1	histone deacetylase 1	0.868
GABARAP	GABA(A) receptor-associated protein	0.866
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.863
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.862
HSPA4	heat shock 70kDa protein 4	0.861
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.859
PSAP	prosaposin	0.855
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.853
TRIM39	tripartite motif containing 39	0.848
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.846
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.845
MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)	0.843
PXN	paxillin	0.843	Human
PSMC5	proteasome (prosome, macropain) 26S subunit, ATPase, 5	0.841
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.837	Human
USP9X	ubiquitin specific peptidase 9, X-linked	0.834	Fly
USP14	ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)	0.833
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.820	Human
PML	promyelocytic leukemia	0.804
UBXN7	UBX domain protein 7	0.803	Yeast
BRCA1	breast cancer 1, early onset	0.803
ANAPC4	anaphase promoting complex subunit 4	0.799
PSMD12	proteasome (prosome, macropain) 26S subunit, non-ATPase, 12	0.794
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	0.779	Yeast
UBE3A	ubiquitin protein ligase E3A	0.774	Mouse Fly
SMAD7	SMAD family member 7	0.773
PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	0.768
RNF5	ring finger protein 5	0.767
PSMB5	proteasome (prosome, macropain) subunit, beta type, 5	0.767	Yeast Mouse
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.761
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.760	Yeast
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.753	Mouse Fly
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.750
NCF1	neutrophil cytosolic factor 1	0.743
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.741	Human
HUWE1	HECT, UBA and WWE domain containing 1	0.739	Human Yeast
BAG3	BCL2-associated athanogene 3	0.736
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.734
CCNA2	cyclin A2	0.732
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.727
DLG4	discs, large homolog 4 (Drosophila)	0.720
FN1	fibronectin 1	0.717
SETDB1	SET domain, bifurcated 1	0.706
GGA2	golgi-associated, gamma adaptin ear containing, ARF binding protein 2	0.703
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.702	Human Mouse
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.693	Human Yeast Fly
ZNRF1	zinc and ring finger 1	0.692	Mouse
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.690
TRIM28	tripartite motif containing 28	0.687	Human
SMAD4	SMAD family member 4	0.684
PPP5C	protein phosphatase 5, catalytic subunit	0.682
DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	0.678	Worm
VHL	von Hippel-Lindau tumor suppressor	0.678	Mouse
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.676	Yeast
TADA3	transcriptional adaptor 3	0.675
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.671
MYD88	myeloid differentiation primary response gene (88)	0.669
PBX1	pre-B-cell leukemia homeobox 1	0.668
ATXN3	ataxin 3	0.667	Mouse
ZMYND11	zinc finger, MYND-type containing 11	0.666
FBXW7	F-box and WD repeat domain containing 7	0.665
RAD23B	RAD23 homolog B (S. cerevisiae)	0.663
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.660	Human
PLK1	polo-like kinase 1	0.659
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.655
GSK3B	glycogen synthase kinase 3 beta	0.653	Mouse Fly
FBXO5	F-box protein 5	0.652
PSMD8	proteasome (prosome, macropain) 26S subunit, non-ATPase, 8	0.650	Yeast
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.648	Mouse Worm
QKI	quaking homolog, KH domain RNA binding (mouse)	0.647
PDCD6IP	programmed cell death 6 interacting protein	0.647
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.645
CBX5	chromobox homolog 5	0.645
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.644	Human
RNF126	ring finger protein 126	0.643
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.643
PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7	0.642
FHL2	four and a half LIM domains 2	0.637
MARCH7	membrane-associated ring finger (C3HC4) 7	0.633
TRAF2	TNF receptor-associated factor 2	0.633	Mouse
EPS15	epidermal growth factor receptor pathway substrate 15	0.628
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.628	Mouse
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.627
GRN	granulin	0.627
AMFR	autocrine motility factor receptor	0.624
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.621
ARRB1	arrestin, beta 1	0.618
CUL5	cullin 5	0.615
EP300	E1A binding protein p300	0.613
ILK	integrin-linked kinase	0.610	Worm
UCHL5	ubiquitin carboxyl-terminal hydrolase L5	0.609
PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)	0.608	Yeast
RNF7	ring finger protein 7	0.601
RNF2	ring finger protein 2	0.599
AXIN1	axin 1	0.599
AR	androgen receptor	0.599
PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)	0.599	Human
DDB1	damage-specific DNA binding protein 1, 127kDa	0.598
PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)	0.596	Human
HSPA1B	heat shock 70kDa protein 1B	0.596	Yeast
TRIM63	tripartite motif containing 63	0.591	Human Mouse
SSR1	signal sequence receptor, alpha	0.589
PSMC4	proteasome (prosome, macropain) 26S subunit, ATPase, 4	0.582	Yeast
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.581
BIRC3	baculoviral IAP repeat containing 3	0.576	Human
PSEN1	presenilin 1	0.574	Mouse
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.572
CUL4A	cullin 4A	0.572	Mouse
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.567	Fly
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.567
BCAR1	breast cancer anti-estrogen resistance 1	0.565
SKP2	S-phase kinase-associated protein 2 (p45)	0.565	Mouse
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.562
UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)	0.558
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.557	Yeast
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.556
H2AFX	H2A histone family, member X	0.555
HSPA13	heat shock protein 70kDa family, member 13	0.550
CHD4	chromodomain helicase DNA binding protein 4	0.549
ADAM15	ADAM metallopeptidase domain 15	0.549
YY1	YY1 transcription factor	0.546
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.541
FBXO7	F-box protein 7	0.531
TLK1	tousled-like kinase 1	0.531	Human
ANAPC7	anaphase promoting complex subunit 7	0.521
UBA1	ubiquitin-like modifier activating enzyme 1	0.513
TRADD	TNFRSF1A-associated via death domain	0.513
HSPA1A	heat shock 70kDa protein 1A	0.499	Yeast
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.494
FLNB	filamin B, beta	0.494	Human
NBR1	neighbor of BRCA1 gene 1	0.493
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.493	Human
SEPT2	septin 2	0.489
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.479
FLNA	filamin A, alpha	0.473
YAP1	Yes-associated protein 1	0.468
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.465
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.460
RFWD2	ring finger and WD repeat domain 2	0.460
UBE2Z	ubiquitin-conjugating enzyme E2Z	0.453	Mouse
PSMB10	proteasome (prosome, macropain) subunit, beta type, 10	0.452	Yeast
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.451
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.448
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.447
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.445
RYBP	RING1 and YY1 binding protein	0.443	Fly
KDM1A	lysine (K)-specific demethylase 1A	0.442
UBXN1	UBX domain protein 1	0.439
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.439
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.439
ANXA7	annexin A7	0.434
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.434
SUMO1	SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae)	0.433
EGFR	epidermal growth factor receptor	0.433
SNF8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	0.432
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.432	Human
MBD3	methyl-CpG binding domain protein 3	0.432
ARAF	v-raf murine sarcoma 3611 viral oncogene homolog	0.430
FBXW2	F-box and WD repeat domain containing 2	0.429
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.426
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.426
UBE2L6	ubiquitin-conjugating enzyme E2L 6	0.418	Mouse
NCF2	neutrophil cytosolic factor 2	0.414
GFI1B	growth factor independent 1B transcription repressor	0.413
UBE2D4	ubiquitin-conjugating enzyme E2D 4 (putative)	0.413	Human Yeast
BRAF	v-raf murine sarcoma viral oncogene homolog B1	0.412	Human
CCT5	chaperonin containing TCP1, subunit 5 (epsilon)	0.412
PLEC	plectin	0.411
UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)	0.411
IRAK1	interleukin-1 receptor-associated kinase 1	0.409	Human
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.408
MYH9	myosin, heavy chain 9, non-muscle	0.402
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.402
FBXO33	F-box protein 33	0.399
CCT7	chaperonin containing TCP1, subunit 7 (eta)	0.398
SELS	selenoprotein S	0.396
UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)	0.393	Yeast Mouse
PKM2	pyruvate kinase, muscle	0.392
WDR26	WD repeat domain 26	0.391
PSMD6	proteasome (prosome, macropain) 26S subunit, non-ATPase, 6	0.390	Zebrafish
MYOZ1	myozenin 1	0.387
PSMD3	proteasome (prosome, macropain) 26S subunit, non-ATPase, 3	0.387
RNF20	ring finger protein 20	0.379
PRKCA	protein kinase C, alpha	0.379
DNM1	dynamin 1	0.379
TRIM43	tripartite motif containing 43	0.379
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.379	Human
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.376
KEAP1	kelch-like ECH-associated protein 1	0.375
VCL	vinculin	0.375	Worm
RNF168	ring finger protein 168	0.369
MKRN1	makorin ring finger protein 1	0.367
ADRM1	adhesion regulating molecule 1	0.365
FGF1	fibroblast growth factor 1 (acidic)	0.364
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.361
LMNA	lamin A/C	0.360	Worm
SEL1L	sel-1 suppressor of lin-12-like (C. elegans)	0.357
SH3GL2	SH3-domain GRB2-like 2	0.354
DLG1	discs, large homolog 1 (Drosophila)	0.353
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.352
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.352	Yeast
CTGF	connective tissue growth factor	0.350
UBE2W	ubiquitin-conjugating enzyme E2W (putative)	0.350	Mouse
NAP1L5	nucleosome assembly protein 1-like 5	0.348
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.347
CDK2	cyclin-dependent kinase 2	0.347
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.346
IGF2R	insulin-like growth factor 2 receptor	0.343
ATM	ataxia telangiectasia mutated	0.340
CDKN3	cyclin-dependent kinase inhibitor 3	0.339
ZNF496	zinc finger protein 496	0.338
DAXX	death-domain associated protein	0.335
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.335	Human
MPDZ	multiple PDZ domain protein	0.333
TRIM21	tripartite motif containing 21	0.333	Human
HTT	huntingtin	0.332
RANBP2	RAN binding protein 2	0.330
TGS1	trimethylguanosine synthase 1	0.328
TP53BP2	tumor protein p53 binding protein, 2	0.328
UBE2L3	ubiquitin-conjugating enzyme E2L 3	0.327
UBE2U	ubiquitin-conjugating enzyme E2U (putative)	0.326
IER3	immediate early response 3	0.325	Mouse
ASF1A	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)	0.324	Worm
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.323
BAD	BCL2-associated agonist of cell death	0.322
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.321	Mouse
ATXN1	ataxin 1	0.320
PJA2	praja ring finger 2	0.319
FAF2	Fas associated factor family member 2	0.318	Human
TGFB1	transforming growth factor, beta 1	0.318
EGLN1	egl nine homolog 1 (C. elegans)	0.317	Human
PKD2	polycystic kidney disease 2 (autosomal dominant)	0.317
EXOC5	exocyst complex component 5	0.317
ADRBK1	adrenergic, beta, receptor kinase 1	0.315
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.312
NBN	nibrin	0.312
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.311
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.310
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.307
ZYX	zyxin	0.303
FZR1	fizzy/cell division cycle 20 related 1 (Drosophila)	0.302
CASP4	caspase 4, apoptosis-related cysteine peptidase	0.301	Human
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.298
OPTN	optineurin	0.297
EPAS1	endothelial PAS domain protein 1	0.296
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.296	Rat
JUN	jun proto-oncogene	0.293
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.292
SIAH1	seven in absentia homolog 1 (Drosophila)	0.292
TRAF5	TNF receptor-associated factor 5	0.291
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.290
CHFR	checkpoint with forkhead and ring finger domains	0.290
KLHL12	kelch-like 12 (Drosophila)	0.289	Human
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.288	Rat
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.287
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.287
COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)	0.287
ITGB4	integrin, beta 4	0.284	Worm
RBCK1	RanBP-type and C3HC4-type zinc finger containing 1	0.280
LIMS1	LIM and senescent cell antigen-like domains 1	0.279	Human
TEKT4	tektin 4	0.278
ANKRD28	ankyrin repeat domain 28	0.276
PRNP	prion protein	0.276
UBQLN2	ubiquilin 2	0.272	Human
RNF31	ring finger protein 31	0.271
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.271
CYBA	cytochrome b-245, alpha polypeptide	0.270
SMAD5	SMAD family member 5	0.270	Human
SUMO3	SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)	0.269	Human Mouse
SMAD1	SMAD family member 1	0.269	Human
FNBP1	formin binding protein 1	0.269
TGFBR1	transforming growth factor, beta receptor 1	0.264	Worm
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.263
STK24	serine/threonine kinase 24	0.262
UBE2M	ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)	0.262
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.261
TRIM32	tripartite motif containing 32	0.259
ANAPC11	anaphase promoting complex subunit 11	0.258	Yeast
UBR1	ubiquitin protein ligase E3 component n-recognin 1	0.258	Mouse
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.258	Human Yeast Mouse Worm
LRRK2	leucine-rich repeat kinase 2	0.257	Mouse
MAGED1	melanoma antigen family D, 1	0.257
CCNB1	cyclin B1	0.256
SFN	stratifin	0.256
RHOB	ras homolog gene family, member B	0.256
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.256
NSFL1C	NSFL1 (p97) cofactor (p47)	0.255	Yeast
IL1R1	interleukin 1 receptor, type I	0.255
BABAM1	BRISC and BRCA1 A complex member 1	0.252
VCPIP1	valosin containing protein (p97)/p47 complex interacting protein 1	0.250
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.249	Human
CENPJ	centromere protein J	0.249
FGFR1	fibroblast growth factor receptor 1	0.248	Worm
FAS	Fas (TNF receptor superfamily, member 6)	0.248
UBXN6	UBX domain protein 6	0.246
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.245	Human
CALD1	caldesmon 1	0.245
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.244
MYO1C	myosin IC	0.243
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.243
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.243	Human
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.242	Yeast
GABARAPL1	GABA(A) receptor-associated protein like 1	0.242
MAGEA3	melanoma antigen family A, 3	0.242
LNX1	ligand of numb-protein X 1	0.242	Mouse
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.242	Fly
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.241
AIPL1	aryl hydrocarbon receptor interacting protein-like 1	0.240
KCTD10	potassium channel tetramerisation domain containing 10	0.239	Human
RIPK2	receptor-interacting serine-threonine kinase 2	0.238	Human
MTA2	metastasis associated 1 family, member 2	0.237	Human
TOM1L1	target of myb1 (chicken)-like 1	0.236
PRKDC	protein kinase, DNA-activated, catalytic polypeptide	0.235
ENG	endoglin	0.235
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.234	Human
TRIB3	tribbles homolog 3 (Drosophila)	0.234	Fly
ARRDC3	arrestin domain containing 3	0.233
CHUK	conserved helix-loop-helix ubiquitous kinase	0.233	Fly
ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	0.233
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.233
COPS3	COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)	0.232	Worm
CCNE2	cyclin E2	0.232	Fly
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.231
NOXA1	NADPH oxidase activator 1	0.231
BAX	BCL2-associated X protein	0.231
VTA1	Vps20-associated 1 homolog (S. cerevisiae)	0.230
MAGEA6	melanoma antigen family A, 6	0.230	Human
TRIM9	tripartite motif containing 9	0.230
APP	amyloid beta (A4) precursor protein	0.226
BCAP31	B-cell receptor-associated protein 31	0.226
RNF130	ring finger protein 130	0.225
TP53BP1	tumor protein p53 binding protein 1	0.225
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.225
CD63	CD63 molecule	0.225
CARM1	coactivator-associated arginine methyltransferase 1	0.224
SNX33	sorting nexin 33	0.224
PSEN2	presenilin 2 (Alzheimer disease 4)	0.224	Mouse
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.223
DR1	down-regulator of transcription 1, TBP-binding (negative cofactor 2)	0.222
ACTB	actin, beta	0.222
CTAG1B	cancer/testis antigen 1B	0.221
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.221
APAF1	apoptotic peptidase activating factor 1	0.220
ATF3	activating transcription factor 3	0.219
FOXM1	forkhead box M1	0.218
HSP90B1	heat shock protein 90kDa beta (Grp94), member 1	0.216
UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)	0.214
RNF8	ring finger protein 8	0.214
S100A4	S100 calcium binding protein A4	0.213
HDAC6	histone deacetylase 6	0.213
WDR48	WD repeat domain 48	0.212
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.212
TCP1	t-complex 1	0.212
MAGEA2	melanoma antigen family A, 2	0.210
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.209
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.208
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.208
FBXW5	F-box and WD repeat domain containing 5	0.208
LDLR	low density lipoprotein receptor	0.207	Mouse
AURKB	aurora kinase B	0.206
FBXL15	F-box and leucine-rich repeat protein 15	0.205
BMP2	bone morphogenetic protein 2	0.205
PICALM	phosphatidylinositol binding clathrin assembly protein	0.204
CSNK1A1	casein kinase 1, alpha 1	0.203	Fly
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.201
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.201
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.201	Yeast
FERMT2	fermitin family member 2	0.201	Worm
ATP13A2	ATPase type 13A2	0.200
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.199
ANXA1	annexin A1	0.199
RANBP9	RAN binding protein 9	0.199
USP15	ubiquitin specific peptidase 15	0.199	Human
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.197
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.194
PARP1	poly (ADP-ribose) polymerase 1	0.194
BCL2	B-cell CLL/lymphoma 2	0.193
ECSIT	ECSIT homolog (Drosophila)	0.190
HERC2	hect domain and RLD 2	0.189
CDCA4	cell division cycle associated 4	0.189
HIST2H3C	histone cluster 2, H3c	0.188	Yeast
ADAM10	ADAM metallopeptidase domain 10	0.188
FBXO3	F-box protein 3	0.188
RNF4	ring finger protein 4	0.186
APC	adenomatous polyposis coli	0.185
RNF14	ring finger protein 14	0.185
ADAM12	ADAM metallopeptidase domain 12	0.184
CCNB2	cyclin B2	0.183
BAG6	BCL2-associated athanogene 6	0.183	Mouse
GCLM	glutamate-cysteine ligase, modifier subunit	0.182
BBS10	Bardet-Biedl syndrome 10	0.182
IRAK2	interleukin-1 receptor-associated kinase 2	0.182	Human
KAT2B	K(lysine) acetyltransferase 2B	0.181
MEOX2	mesenchyme homeobox 2	0.180
SOCS1	suppressor of cytokine signaling 1	0.179	Human
STAT5A	signal transducer and activator of transcription 5A	0.179
A2M	alpha-2-macroglobulin	0.178
DTX3L	deltex 3-like (Drosophila)	0.178
PCBP2	poly(rC) binding protein 2	0.178
PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase	0.178
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.178
KLC1	kinesin light chain 1	0.178
RB1CC1	RB1-inducible coiled-coil 1	0.178
ITGB5	integrin, beta 5	0.178	Worm
IQGAP1	IQ motif containing GTPase activating protein 1	0.177
TPBG	trophoblast glycoprotein	0.176
CD14	CD14 molecule	0.176
THBS1	thrombospondin 1	0.175
KALRN	kalirin, RhoGEF kinase	0.174	Worm
MIB1	mindbomb homolog 1 (Drosophila)	0.174
MAVS	mitochondrial antiviral signaling protein	0.174
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.174	Yeast
ITK	IL2-inducible T-cell kinase	0.174
GRB7	growth factor receptor-bound protein 7	0.174
SLC39A7	solute carrier family 39 (zinc transporter), member 7	0.173
MAP2K4	mitogen-activated protein kinase kinase 4	0.173
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.173
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.173	Human
TRIM5	tripartite motif containing 5	0.172	Human Mouse
RNF185	ring finger protein 185	0.172	Human
TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	0.171
NLRC4	NLR family, CARD domain containing 4	0.170
HTRA2	HtrA serine peptidase 2	0.170
USP34	ubiquitin specific peptidase 34	0.169
CAND1	cullin-associated and neddylation-dissociated 1	0.168
DAPK1	death-associated protein kinase 1	0.168
PPFIA1	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1	0.168
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.167
TSG101	tumor susceptibility gene 101	0.164
UBA3	ubiquitin-like modifier activating enzyme 3	0.164
PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)	0.163
HIF1AN	hypoxia inducible factor 1, alpha subunit inhibitor	0.162
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.161
IL1RAP	interleukin 1 receptor accessory protein	0.160
SON	SON DNA binding protein	0.160
DCAF7	DDB1 and CUL4 associated factor 7	0.160
FOXO3	forkhead box O3	0.159	Human
BFAR	bifunctional apoptosis regulator	0.159
PDIA6	protein disulfide isomerase family A, member 6	0.158
TOPORS	topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase	0.158
RNF144B	ring finger protein 144B	0.157
TBC1D10A	TBC1 domain family, member 10A	0.157
IL22RA2	interleukin 22 receptor, alpha 2	0.156
AGAP5	ArfGAP with GTPase domain, ankyrin repeat and PH domain 5	0.155	Human
SP1	Sp1 transcription factor	0.155
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.155
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.155
BMP1	bone morphogenetic protein 1	0.154
NDUFAF3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3	0.154
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.154
CCDC115	coiled-coil domain containing 115	0.153
VPS28	vacuolar protein sorting 28 homolog (S. cerevisiae)	0.153
VPRBP	Vpr (HIV-1) binding protein	0.151
NRP1	neuropilin 1	0.151
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.151	Human
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.151
RNF10	ring finger protein 10	0.151
SESN2	sestrin 2	0.150
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.150
SETD7	SET domain containing (lysine methyltransferase) 7	0.150
FEN1	flap structure-specific endonuclease 1	0.150
CD44	CD44 molecule (Indian blood group)	0.149
DUSP1	dual specificity phosphatase 1	0.149
GRB2	growth factor receptor-bound protein 2	0.148
SOCS5	suppressor of cytokine signaling 5	0.146
BAK1	BCL2-antagonist/killer 1	0.146
ARNTL	aryl hydrocarbon receptor nuclear translocator-like	0.146	Mouse
ZBTB8A	zinc finger and BTB domain containing 8A	0.146
CSNK1D	casein kinase 1, delta	0.145	Mouse Fly
EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3	0.145
SNAP23	synaptosomal-associated protein, 23kDa	0.145
PTEN	phosphatase and tensin homolog	0.145
SNX6	sorting nexin 6	0.145
PCBP1	poly(rC) binding protein 1	0.144	Human
MAP2K1	mitogen-activated protein kinase kinase 1	0.144	Worm
ZNF746	zinc finger protein 746	0.144
TLR2	toll-like receptor 2	0.144
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.143
C11orf58	chromosome 11 open reading frame 58	0.143
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.143	Human
NCAM1	neural cell adhesion molecule 1	0.143
NUDCD3	NudC domain containing 3	0.142
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.142
CKAP5	cytoskeleton associated protein 5	0.142
SEC61A1	Sec61 alpha 1 subunit (S. cerevisiae)	0.141	Yeast
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.141
EID2	EP300 interacting inhibitor of differentiation 2	0.141
RIOK3	RIO kinase 3 (yeast)	0.140
FZD7	frizzled homolog 7 (Drosophila)	0.140
CLOCK	clock homolog (mouse)	0.140	Mouse
ACVR1	activin A receptor, type I	0.140	Worm
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.140
MAGEB18	melanoma antigen family B, 18	0.139	Human
GSTO1	glutathione S-transferase omega 1	0.139
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.138
EPOR	erythropoietin receptor	0.138
PRKCD	protein kinase C, delta	0.137	Human
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.137
MKI67	antigen identified by monoclonal antibody Ki-67	0.137
FKBP1A	FK506 binding protein 1A, 12kDa	0.137
DTX1	deltex homolog 1 (Drosophila)	0.137
SCYL2	SCY1-like 2 (S. cerevisiae)	0.136
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.136
MAP2K2	mitogen-activated protein kinase kinase 2	0.136	Worm
EGLN3	egl nine homolog 3 (C. elegans)	0.136	Human
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.136
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.135
TRIM34	tripartite motif containing 34	0.135
DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10	0.135
WAC	WW domain containing adaptor with coiled-coil	0.135
TROVE2	TROVE domain family, member 2	0.134
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.134
CHEK2	CHK2 checkpoint homolog (S. pombe)	0.134
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.134
RNF38	ring finger protein 38	0.134
ACTN1	actinin, alpha 1	0.134	Worm
SKA3	spindle and kinetochore associated complex subunit 3	0.133
TM9SF3	transmembrane 9 superfamily member 3	0.133
CCL3	chemokine (C-C motif) ligand 3	0.132
CP110	CP110 protein	0.132
SPC25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.132
OXSR1	oxidative-stress responsive 1	0.132
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.132
GRIN2B	glutamate receptor, ionotropic, N-methyl D-aspartate 2B	0.131
NCK2	NCK adaptor protein 2	0.131
TNIP1	TNFAIP3 interacting protein 1	0.131
PRPF40A	PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)	0.131
PCM1	pericentriolar material 1	0.131
CDYL	chromodomain protein, Y-like	0.131
HNRNPL	heterogeneous nuclear ribonucleoprotein L	0.131
CHMP1A	chromatin modifying protein 1A	0.131
RPN1	ribophorin I	0.130
UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	0.130
TFDP1	transcription factor Dp-1	0.130
ARPP19	cAMP-regulated phosphoprotein, 19kDa	0.130
RAB14	RAB14, member RAS oncogene family	0.130
MAPK8	mitogen-activated protein kinase 8	0.130
AGAP7	ArfGAP with GTPase domain, ankyrin repeat and PH domain 7	0.129	Human
ZYG11B	zyg-11 homolog B (C. elegans)	0.129
TRIM33	tripartite motif containing 33	0.129	Human
TPP1	tripeptidyl peptidase I	0.128
PRC1	protein regulator of cytokinesis 1	0.128
PARP9	poly (ADP-ribose) polymerase family, member 9	0.127
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.127	Human Mouse Fly
DHPS	deoxyhypusine synthase	0.127
TXN	thioredoxin	0.127
SOCS6	suppressor of cytokine signaling 6	0.127
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.127
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.127
SEC24B	SEC24 family, member B (S. cerevisiae)	0.127
USP8	ubiquitin specific peptidase 8	0.127	Yeast
ZNF263	zinc finger protein 263	0.126
BTBD10	BTB (POZ) domain containing 10	0.126
MAPK6	mitogen-activated protein kinase 6	0.126
RIPK3	receptor-interacting serine-threonine kinase 3	0.126	Human
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.126	Human
SH3KBP1	SH3-domain kinase binding protein 1	0.125
WEE1	WEE1 homolog (S. pombe)	0.125
LIMK1	LIM domain kinase 1	0.125
LCAT	lecithin-cholesterol acyltransferase	0.124
CCND1	cyclin D1	0.124
MED1	mediator complex subunit 1	0.124
MAP1A	microtubule-associated protein 1A	0.124
CD2	CD2 molecule	0.124
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.123
TRIM23	tripartite motif containing 23	0.123
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.123
PJA1	praja ring finger 1	0.123	Mouse
KRT15	keratin 15	0.123
COPS6	COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)	0.122
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.122
PCYT2	phosphate cytidylyltransferase 2, ethanolamine	0.122
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.122
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.122
FAM175B	family with sequence similarity 175, member B	0.122
TRIM8	tripartite motif containing 8	0.121	Human Yeast
TLK2	tousled-like kinase 2	0.121
PLOD3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3	0.121
TUBB2C	tubulin, beta 2C	0.121
USP2	ubiquitin specific peptidase 2	0.121	Yeast Fly
EEF2	eukaryotic translation elongation factor 2	0.120
IL10RA	interleukin 10 receptor, alpha	0.119
E2F1	E2F transcription factor 1	0.119
STMN1	stathmin 1	0.119
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.119
MED15	mediator complex subunit 15	0.118
CANX	calnexin	0.118
ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)	0.118
EID2B	EP300 interacting inhibitor of differentiation 2B	0.117
SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	0.117
FEM1B	fem-1 homolog b (C. elegans)	0.117
KPNA4	karyopherin alpha 4 (importin alpha 3)	0.117
MAP1B	microtubule-associated protein 1B	0.116
EIF1B	eukaryotic translation initiation factor 1B	0.116
PRKCB	protein kinase C, beta	0.116
PAIP2	poly(A) binding protein interacting protein 2	0.116
GFM1	G elongation factor, mitochondrial 1	0.116
FSTL1	follistatin-like 1	0.115
HIPK3	homeodomain interacting protein kinase 3	0.115
CDT1	chromatin licensing and DNA replication factor 1	0.115
MTA3	metastasis associated 1 family, member 3	0.115	Human
PIM1	pim-1 oncogene	0.115
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.115	Mouse
SPRY2	sprouty homolog 2 (Drosophila)	0.114
CHMP4B	chromatin modifying protein 4B	0.114
RFWD3	ring finger and WD repeat domain 3	0.114
MYO10	myosin X	0.114
TSC22D1	TSC22 domain family, member 1	0.114
C19orf39	chromosome 19 open reading frame 39	0.114
TRAF4	TNF receptor-associated factor 4	0.114
ZMYND19	zinc finger, MYND-type containing 19	0.114
MARCH5	membrane-associated ring finger (C3HC4) 5	0.114
UBE2J1	ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast)	0.114
DERL2	Der1-like domain family, member 2	0.113
TMEM173	transmembrane protein 173	0.113
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.113
SEC63	SEC63 homolog (S. cerevisiae)	0.112
ATN1	atrophin 1	0.112
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.112
RANBP3	RAN binding protein 3	0.112
SSX4	synovial sarcoma, X breakpoint 4	0.112
CLTA	clathrin, light chain A	0.112
SGOL2	shugoshin-like 2 (S. pombe)	0.112
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.111
UBE2C	ubiquitin-conjugating enzyme E2C	0.111
ADNP	activity-dependent neuroprotector homeobox	0.111
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.111
STRN3	striatin, calmodulin binding protein 3	0.111
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.111
PNPLA2	patatin-like phospholipase domain containing 2	0.111
GATAD2B	GATA zinc finger domain containing 2B	0.111
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.110
ANAPC5	anaphase promoting complex subunit 5	0.110
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.110	Human
GORAB	golgin, RAB6-interacting	0.110
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.109
USP18	ubiquitin specific peptidase 18	0.109
NKAP	NFKB activating protein	0.109
PTGES3	prostaglandin E synthase 3 (cytosolic)	0.109
MYST1	MYST histone acetyltransferase 1	0.109	Human
ARF4	ADP-ribosylation factor 4	0.108
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.108	Yeast
RBL2	retinoblastoma-like 2 (p130)	0.108	Human
CSNK1E	casein kinase 1, epsilon	0.108	Mouse Fly
TRIM41	tripartite motif containing 41	0.108	Human
GET4	golgi to ER traffic protein 4 homolog (S. cerevisiae)	0.108
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.108
PHAX	phosphorylated adaptor for RNA export	0.108
N4BP1	NEDD4 binding protein 1	0.108	Mouse
IFNGR1	interferon gamma receptor 1	0.107
AMBP	alpha-1-microglobulin/bikunin precursor	0.107	Rat
INO80	INO80 homolog (S. cerevisiae)	0.107
RACGAP1	Rac GTPase activating protein 1	0.107
CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)	0.106
NAA35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit	0.106
TGFB2	transforming growth factor, beta 2	0.106
EIF5	eukaryotic translation initiation factor 5	0.106
CXCL10	chemokine (C-X-C motif) ligand 10	0.106
PACS1	phosphofurin acidic cluster sorting protein 1	0.106
AXIN2	axin 2	0.106	Human
SPCS3	signal peptidase complex subunit 3 homolog (S. cerevisiae)	0.105
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.105
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.105
MAGEA12	melanoma antigen family A, 12	0.105	Human
HOOK3	hook homolog 3 (Drosophila)	0.105
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.105
ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2	0.105
OPA1	optic atrophy 1 (autosomal dominant)	0.104	Worm
ACVR1B	activin A receptor, type IB	0.104	Worm
UBE2O	ubiquitin-conjugating enzyme E2O	0.104
PAIP1	poly(A) binding protein interacting protein 1	0.104
NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. pombe)	0.104
SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	0.104