IMP
Process View
trna aminoacylation
The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
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In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "trna aminoacylation"
| Name | Description | Probability | Func Analog Organism | |
|---|---|---|---|---|
| IARS | isoleucyl-tRNA synthetase | 1.000 | Yeast | |
| EPRS | glutamyl-prolyl-tRNA synthetase | 1.000 | ||
| GARS | glycyl-tRNA synthetase | 1.000 | Yeast | |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | 0.991 | ||
| MARS | methionyl-tRNA synthetase | 0.989 | Yeast | |
| AARS | alanyl-tRNA synthetase | 0.982 | Mouse Rat | |
| AIMP2 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | 0.975 | ||
| NARS | asparaginyl-tRNA synthetase | 0.932 | Yeast | |
| YARS | tyrosyl-tRNA synthetase | 0.931 | ||
| KARS | lysyl-tRNA synthetase | 0.842 | ||
| RARS | arginyl-tRNA synthetase | 0.788 | Rat | |
| CARS | cysteinyl-tRNA synthetase | 0.696 | ||
| LARS | leucyl-tRNA synthetase | 0.685 | Yeast | |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) | 0.476 | ||
| SARS | seryl-tRNA synthetase | 0.464 | Yeast | |
| BCS1L | BCS1-like (S. cerevisiae) | 0.193 | ||
| TARS | threonyl-tRNA synthetase | 0.162 | Yeast | |
| XPOT | exportin, tRNA (nuclear export receptor for tRNAs) | 0.137 | ||
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.129 | ||
| ATIC | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase | 0.119 | ||
| AIMP1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 | 0.088 | ||
| GOT1 | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 0.078 | ||
| OTUD5 | OTU domain containing 5 | 0.053 | ||
| GART | phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase | 0.052 | ||
| XPO5 | exportin 5 | 0.044 | ||
| DARS | aspartyl-tRNA synthetase | 0.041 | Yeast | |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.039 | ||
| LRPPRC | leucine-rich PPR-motif containing | 0.036 | ||
| BOP1 | block of proliferation 1 | 0.035 | ||
| WDR46 | WD repeat domain 46 | 0.031 | ||
| MRPS27 | mitochondrial ribosomal protein S27 | 0.027 | ||
| MINA | MYC induced nuclear antigen | 0.026 | ||
| EIF3CL | eukaryotic translation initiation factor 3, subunit C-like | 0.023 | ||
| CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.023 | ||
| EIF2B3 | eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa | 0.023 | ||
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.023 | ||
| BMS1 | BMS1 homolog, ribosome assembly protein (yeast) | 0.022 | ||
| LARS2 | leucyl-tRNA synthetase 2, mitochondrial | 0.021 | ||
| PUS1 | pseudouridylate synthase 1 | 0.021 | ||
| PSAT1 | phosphoserine aminotransferase 1 | 0.020 | ||
| OGFOD1 | 2-oxoglutarate and iron-dependent oxygenase domain containing 1 | 0.020 | ||
| ECSIT | ECSIT homolog (Drosophila) | 0.019 | ||
| CNO | cappuccino homolog (mouse) | 0.019 | ||
| KRT8 | keratin 8 | 0.019 | ||
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.018 | ||
| EEF1E1 | eukaryotic translation elongation factor 1 epsilon 1 | 0.018 | ||
| METTL13 | methyltransferase like 13 | 0.017 | ||
| ARMC6 | armadillo repeat containing 6 | 0.016 | ||
| LIAS | lipoic acid synthetase | 0.015 | ||
| FKBP4 | FK506 binding protein 4, 59kDa | 0.014 | ||
| DAP3 | death associated protein 3 | 0.014 | ||
| TSEN2 | tRNA splicing endonuclease 2 homolog (S. cerevisiae) | 0.014 | ||
| FARSB | phenylalanyl-tRNA synthetase, beta subunit | 0.013 | ||
| EIF2B2 | eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa | 0.013 | ||
| UBA5 | ubiquitin-like modifier activating enzyme 5 | 0.013 | ||
| SKIV2L2 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) | 0.013 | ||
| GEMIN5 | gem (nuclear organelle) associated protein 5 | 0.012 | ||
| VARS | valyl-tRNA synthetase | 0.012 | Yeast | |
| THG1L | tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) | 0.012 | ||
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.012 | ||
| METTL17 | methyltransferase like 17 | 0.012 | ||
| C12orf44 | chromosome 12 open reading frame 44 | 0.012 | ||
| POLR1A | polymerase (RNA) I polypeptide A, 194kDa | 0.011 | ||
| RTN4IP1 | reticulon 4 interacting protein 1 | 0.011 | ||
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.011 | ||
| MRRF | mitochondrial ribosome recycling factor | 0.010 | ||
| MRPS9 | mitochondrial ribosomal protein S9 | 0.010 | ||
| NAT10 | N-acetyltransferase 10 (GCN5-related) | 0.010 | ||
| APEX1 | APEX nuclease (multifunctional DNA repair enzyme) 1 | 0.010 | ||
| MTRR | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 0.010 |