Process View
The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "i kappab kinase nf kappab signaling"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 1.000 | ||
TRAF6 | TNF receptor-associated factor 6 | 1.000 | ||
TRAF2 | TNF receptor-associated factor 2 | 1.000 | Human | |
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 1.000 | ||
BIRC3 | baculoviral IAP repeat containing 3 | 1.000 | Human | |
XIAP | X-linked inhibitor of apoptosis | 1.000 | Human | |
RIPK2 | receptor-interacting serine-threonine kinase 2 | 1.000 | ||
UBC | ubiquitin C | 1.000 | ||
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 1.000 | ||
MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 1.000 | ||
SQSTM1 | sequestosome 1 | 1.000 | ||
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 1.000 | Human Mouse | |
TRAF1 | TNF receptor-associated factor 1 | 1.000 | Human | |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 1.000 | ||
TRAF3 | TNF receptor-associated factor 3 | 1.000 | Human | |
RELA | v-rel reticuloendotheliosis viral oncogene homolog A (avian) | 0.999 | ||
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.998 | ||
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.998 | ||
NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.996 | Human | |
TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.994 | ||
CASP1 | caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase) | 0.994 | ||
MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.993 | ||
FLNA | filamin A, alpha | 0.993 | ||
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.992 | ||
MYD88 | myeloid differentiation primary response gene (88) | 0.992 | ||
UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 0.990 | ||
RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.990 | ||
TRADD | TNFRSF1A-associated via death domain | 0.988 | ||
IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.988 | ||
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.980 | ||
TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | 0.980 | ||
TNIP2 | TNFAIP3 interacting protein 2 | 0.978 | ||
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.977 | ||
BIRC2 | baculoviral IAP repeat containing 2 | 0.976 | ||
CFLAR | CASP8 and FADD-like apoptosis regulator | 0.974 | ||
S100A6 | S100 calcium binding protein A6 | 0.973 | Human | |
SMAD3 | SMAD family member 3 | 0.973 | ||
FAS | Fas (TNF receptor superfamily, member 6) | 0.971 | Human | |
ESR1 | estrogen receptor 1 | 0.964 | ||
IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.964 | Human | |
CHUK | conserved helix-loop-helix ubiquitous kinase | 0.961 | Human Zebrafish Mouse | |
CARD11 | caspase recruitment domain family, member 11 | 0.956 | Human Mouse | |
IRAK1 | interleukin-1 receptor-associated kinase 1 | 0.954 | ||
NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.951 | Human | |
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.947 | ||
FADD | Fas (TNFRSF6)-associated via death domain | 0.944 | ||
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta | 0.939 | Human Rat | |
IL1B | interleukin 1, beta | 0.933 | ||
CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.924 | ||
JAG1 | jagged 1 | 0.903 | ||
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.888 | ||
ZNF43 | zinc finger protein 43 | 0.888 | ||
TNF | tumor necrosis factor | 0.884 | ||
TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | 0.882 | ||
PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.875 | ||
NOTCH1 | notch 1 | 0.871 | Fly | |
DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.869 | ||
RELB | v-rel reticuloendotheliosis viral oncogene homolog B | 0.867 | Human | |
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.867 | Human | |
CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.864 | ||
MAP3K3 | mitogen-activated protein kinase kinase kinase 3 | 0.861 | ||
IL1R1 | interleukin 1 receptor, type I | 0.850 | ||
ZNF675 | zinc finger protein 675 | 0.846 | ||
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.840 | ||
IRF1 | interferon regulatory factor 1 | 0.836 | ||
TNFRSF14 | tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator) | 0.834 | Human | |
S100B | S100 calcium binding protein B | 0.821 | ||
TP53 | tumor protein p53 | 0.806 | ||
CCL4 | chemokine (C-C motif) ligand 4 | 0.792 | Human | |
PML | promyelocytic leukemia | 0.790 | ||
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.765 | ||
MAP3K8 | mitogen-activated protein kinase kinase kinase 8 | 0.751 | ||
S100A9 | S100 calcium binding protein A9 | 0.738 | Human | |
S100A8 | S100 calcium binding protein A8 | 0.726 | Human | |
TNFRSF10A | tumor necrosis factor receptor superfamily, member 10a | 0.715 | Human | |
TNIP1 | TNFAIP3 interacting protein 1 | 0.712 | ||
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 0.704 | ||
IL8 | interleukin 8 | 0.699 | ||
HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.693 | ||
S100A16 | S100 calcium binding protein A16 | 0.676 | Human | |
ANXA1 | annexin A1 | 0.673 | ||
CXCL2 | chemokine (C-X-C motif) ligand 2 | 0.656 | ||
S100A14 | S100 calcium binding protein A14 | 0.654 | Human | |
SFN | stratifin | 0.648 | ||
MYH9 | myosin, heavy chain 9, non-muscle | 0.645 | ||
ANXA2 | annexin A2 | 0.640 | ||
NLRC4 | NLR family, CARD domain containing 4 | 0.632 | ||
BCL3 | B-cell CLL/lymphoma 3 | 0.615 | ||
ARRB1 | arrestin, beta 1 | 0.612 | ||
CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.612 | Human | |
ZNF253 | zinc finger protein 253 | 0.612 | ||
TRAF5 | TNF receptor-associated factor 5 | 0.609 | ||
BCL10 | B-cell CLL/lymphoma 10 | 0.602 | ||
TICAM2 | toll-like receptor adaptor molecule 2 | 0.602 | ||
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.580 | ||
STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.577 | Human | |
S100A4 | S100 calcium binding protein A4 | 0.576 | ||
LATS2 | LATS, large tumor suppressor, homolog 2 (Drosophila) | 0.574 | ||
PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.565 | ||
PSEN1 | presenilin 1 | 0.559 | ||
CCL2 | chemokine (C-C motif) ligand 2 | 0.556 | Human | |
FKBP4 | FK506 binding protein 4, 59kDa | 0.551 | ||
ACTN4 | actinin, alpha 4 | 0.542 | ||
SRC | v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | 0.524 | ||
PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.518 | ||
IFNAR1 | interferon (alpha, beta and omega) receptor 1 | 0.517 | ||
ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.511 | ||
TRIM63 | tripartite motif containing 63 | 0.503 | Human | |
CXCL9 | chemokine (C-X-C motif) ligand 9 | 0.502 | ||
CCR5 | chemokine (C-C motif) receptor 5 | 0.498 | ||
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.489 | ||
S100A11 | S100 calcium binding protein A11 | 0.481 | Human | |
IL4R | interleukin 4 receptor | 0.477 | ||
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.467 | ||
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 0.462 | ||
CCL5 | chemokine (C-C motif) ligand 5 | 0.462 | Human | |
ABL1 | c-abl oncogene 1, non-receptor tyrosine kinase | 0.453 | Mouse | |
LTA | lymphotoxin alpha (TNF superfamily, member 1) | 0.441 | ||
MED15 | mediator complex subunit 15 | 0.440 | ||
IL6 | interleukin 6 (interferon, beta 2) | 0.431 | ||
ZNF273 | zinc finger protein 273 | 0.428 | Human | |
CXCL3 | chemokine (C-X-C motif) ligand 3 | 0.419 | ||
USP15 | ubiquitin specific peptidase 15 | 0.411 | ||
CCL8 | chemokine (C-C motif) ligand 8 | 0.409 | Human | |
IL2RB | interleukin 2 receptor, beta | 0.408 | ||
UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.401 | ||
RNF31 | ring finger protein 31 | 0.398 | ||
GBP2 | guanylate binding protein 2, interferon-inducible | 0.395 | ||
NCF1 | neutrophil cytosolic factor 1 | 0.390 | ||
NR0B1 | nuclear receptor subfamily 0, group B, member 1 | 0.388 | ||
TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.385 | ||
CD14 | CD14 molecule | 0.380 | ||
S100A1 | S100 calcium binding protein A1 | 0.379 | Human | |
FBXW11 | F-box and WD repeat domain containing 11 | 0.378 | Mouse Fly | |
NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.372 | Human | |
CXCL10 | chemokine (C-X-C motif) ligand 10 | 0.368 | ||
IRF7 | interferon regulatory factor 7 | 0.363 | ||
PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.362 | ||
SKP1 | S-phase kinase-associated protein 1 | 0.361 | ||
IL1R2 | interleukin 1 receptor, type II | 0.360 | ||
EGFR | epidermal growth factor receptor | 0.359 | ||
CBL | Cas-Br-M (murine) ecotropic retroviral transforming sequence | 0.357 | ||
BTRC | beta-transducin repeat containing | 0.352 | Mouse Fly | |
DAXX | death-domain associated protein | 0.344 | ||
DTX3L | deltex 3-like (Drosophila) | 0.343 | ||
LMNA | lamin A/C | 0.332 | ||
TLR4 | toll-like receptor 4 | 0.331 | ||
SMAD4 | SMAD family member 4 | 0.329 | ||
ZNF84 | zinc finger protein 84 | 0.329 | ||
RNF11 | ring finger protein 11 | 0.325 | ||
TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 | 0.319 | ||
MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.316 | ||
TBK1 | TANK-binding kinase 1 | 0.314 | ||
FASLG | Fas ligand (TNF superfamily, member 6) | 0.312 | ||
CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.311 | ||
NMI | N-myc (and STAT) interactor | 0.308 | ||
EEF1G | eukaryotic translation elongation factor 1 gamma | 0.304 | ||
SNAI1 | snail homolog 1 (Drosophila) | 0.304 | ||
ZFP30 | zinc finger protein 30 homolog (mouse) | 0.302 | ||
TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B | 0.302 | Human | |
CCL19 | chemokine (C-C motif) ligand 19 | 0.296 | ||
LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.296 | ||
HIPK3 | homeodomain interacting protein kinase 3 | 0.295 | ||
CREBBP | CREB binding protein | 0.291 | ||
ACVR1B | activin A receptor, type IB | 0.291 | ||
ZC3H12A | zinc finger CCCH-type containing 12A | 0.286 | ||
CCL22 | chemokine (C-C motif) ligand 22 | 0.282 | Human | |
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.281 | ||
ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.280 | Human | |
UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 0.280 | ||
MYO1C | myosin IC | 0.280 | ||
FLNB | filamin B, beta | 0.279 | Human | |
ICAM1 | intercellular adhesion molecule 1 | 0.276 | ||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.276 | ||
MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.266 | ||
ZNF260 | zinc finger protein 260 | 0.265 | ||
EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.262 | ||
ZNF254 | zinc finger protein 254 | 0.256 | Human | |
TRIM27 | tripartite motif containing 27 | 0.256 | Human | |
OAS1 | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 0.254 | ||
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.253 | ||
ARHGAP1 | Rho GTPase activating protein 1 | 0.247 | ||
PRKCA | protein kinase C, alpha | 0.246 | ||
ZNF85 | zinc finger protein 85 | 0.245 | Human | |
TMSB10 | thymosin beta 10 | 0.244 | ||
TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.243 | ||
MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.242 | ||
TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 | 0.240 | ||
C14orf1 | chromosome 14 open reading frame 1 | 0.239 | ||
APAF1 | apoptotic peptidase activating factor 1 | 0.239 | ||
HDAC2 | histone deacetylase 2 | 0.239 | ||
CXCL11 | chemokine (C-X-C motif) ligand 11 | 0.238 | ||
ZMYND11 | zinc finger, MYND-type containing 11 | 0.235 | ||
TMED10 | transmembrane emp24-like trafficking protein 10 (yeast) | 0.234 | ||
STAT6 | signal transducer and activator of transcription 6, interleukin-4 induced | 0.234 | Human | |
CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | 0.223 | Human | |
TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.220 | ||
BAG3 | BCL2-associated athanogene 3 | 0.220 | ||
ZNF91 | zinc finger protein 91 | 0.219 | ||
MTOR | mechanistic target of rapamycin (serine/threonine kinase) | 0.216 | ||
NUMBL | numb homolog (Drosophila)-like | 0.213 | ||
GBP1 | guanylate binding protein 1, interferon-inducible | 0.212 | ||
ZNF567 | zinc finger protein 567 | 0.210 | ||
AHNAK | AHNAK nucleoprotein | 0.209 | ||
IRAK4 | interleukin-1 receptor-associated kinase 4 | 0.206 | ||
LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.205 | ||
JAK2 | Janus kinase 2 | 0.204 | ||
TXN | thioredoxin | 0.203 | ||
TMEM173 | transmembrane protein 173 | 0.202 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.202 | ||
FTH1 | ferritin, heavy polypeptide 1 | 0.200 | ||
LILRB1 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1 | 0.199 | ||
TP63 | tumor protein p63 | 0.197 | ||
FBXO7 | F-box protein 7 | 0.196 | ||
MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.196 | ||
CCR1 | chemokine (C-C motif) receptor 1 | 0.195 | ||
CYLD | cylindromatosis (turban tumor syndrome) | 0.194 | ||
STAP2 | signal transducing adaptor family member 2 | 0.193 | ||
CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | 0.192 | ||
UBASH3B | ubiquitin associated and SH3 domain containing B | 0.192 | ||
SMAD2 | SMAD family member 2 | 0.190 | ||
TRIM8 | tripartite motif containing 8 | 0.189 | ||
CCR7 | chemokine (C-C motif) receptor 7 | 0.189 | ||
CCL20 | chemokine (C-C motif) ligand 20 | 0.188 | Human | |
CSNK1E | casein kinase 1, epsilon | 0.187 | ||
CCNT1 | cyclin T1 | 0.186 | ||
STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.184 | ||
TEK | TEK tyrosine kinase, endothelial | 0.183 | ||
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.182 | ||
SKIL | SKI-like oncogene | 0.182 | ||
OPTN | optineurin | 0.181 | ||
S100A10 | S100 calcium binding protein A10 | 0.180 | Human | |
AZI2 | 5-azacytidine induced 2 | 0.179 | ||
MAVS | mitochondrial antiviral signaling protein | 0.179 | ||
IL7R | interleukin 7 receptor | 0.179 | ||
VIM | vimentin | 0.179 | ||
CCL7 | chemokine (C-C motif) ligand 7 | 0.177 | Human | |
TICAM1 | toll-like receptor adaptor molecule 1 | 0.177 | ||
IFNG | interferon, gamma | 0.176 | ||
TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.175 | ||
ZNF420 | zinc finger protein 420 | 0.174 | ||
MPDZ | multiple PDZ domain protein | 0.173 | ||
ZNF93 | zinc finger protein 93 | 0.172 | ||
RHOG | ras homolog gene family, member G (rho G) | 0.170 | ||
RIN1 | Ras and Rab interactor 1 | 0.170 | ||
AREG | amphiregulin | 0.167 | ||
HIPK2 | homeodomain interacting protein kinase 2 | 0.166 | ||
RUNX3 | runt-related transcription factor 3 | 0.163 | ||
RANBP3 | RAN binding protein 3 | 0.161 | ||
NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.160 | ||
SMAD7 | SMAD family member 7 | 0.159 | ||
ZNF708 | zinc finger protein 708 | 0.158 | Human | |
LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.156 | Human | |
XIRP1 | xin actin-binding repeat containing 1 | 0.156 | ||
MAML1 | mastermind-like 1 (Drosophila) | 0.153 | ||
SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) | 0.153 | ||
SOCS3 | suppressor of cytokine signaling 3 | 0.152 | ||
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.152 | ||
SMAD1 | SMAD family member 1 | 0.151 | ||
CCL13 | chemokine (C-C motif) ligand 13 | 0.151 | Human | |
PELI3 | pellino homolog 3 (Drosophila) | 0.151 | ||
JAK3 | Janus kinase 3 | 0.150 | ||
RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.149 | Human Mouse | |
JUN | jun proto-oncogene | 0.149 | ||
TLR2 | toll-like receptor 2 | 0.149 | ||
TRIM25 | tripartite motif containing 25 | 0.148 | ||
ACTB | actin, beta | 0.146 | ||
TRAF3IP2 | TRAF3 interacting protein 2 | 0.146 | ||
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.145 | ||
ZNF117 | zinc finger protein 117 | 0.145 | Human | |
TTN | titin | 0.145 | ||
DPP4 | dipeptidyl-peptidase 4 | 0.145 | ||
ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.144 | ||
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.143 | ||
RTP4 | receptor (chemosensory) transporter protein 4 | 0.142 | ||
GSK3B | glycogen synthase kinase 3 beta | 0.142 | ||
HSPA1L | heat shock 70kDa protein 1-like | 0.140 | ||
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.140 | ||
ATXN3 | ataxin 3 | 0.139 | ||
TRIM32 | tripartite motif containing 32 | 0.136 | ||
TRIM5 | tripartite motif containing 5 | 0.134 | ||
OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.134 | ||
USP2 | ubiquitin specific peptidase 2 | 0.133 | ||
ITGB4 | integrin, beta 4 | 0.133 | ||
IL2RG | interleukin 2 receptor, gamma | 0.133 | ||
RRAS | related RAS viral (r-ras) oncogene homolog | 0.132 | ||
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.132 | ||
PPP5C | protein phosphatase 5, catalytic subunit | 0.132 | ||
C1orf93 | chromosome 1 open reading frame 93 | 0.130 | ||
MESDC2 | mesoderm development candidate 2 | 0.129 | ||
ZNRF1 | zinc and ring finger 1 | 0.129 | ||
ATM | ataxia telangiectasia mutated | 0.128 | ||
IL12RB2 | interleukin 12 receptor, beta 2 | 0.127 | ||
ZNF746 | zinc finger protein 746 | 0.126 | ||
IFNAR2 | interferon (alpha, beta and omega) receptor 2 | 0.126 | ||
ZNF430 | zinc finger protein 430 | 0.126 | Human | |
JAG2 | jagged 2 | 0.125 | ||
TANK | TRAF family member-associated NFKB activator | 0.123 | Mouse | |
ZNF585A | zinc finger protein 585A | 0.122 | ||
BTN3A2 | butyrophilin, subfamily 3, member A2 | 0.122 | ||
SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) | 0.122 | ||
PFN1 | profilin 1 | 0.120 | ||
SPEN | spen homolog, transcriptional regulator (Drosophila) | 0.119 | ||
LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | 0.119 | ||
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.118 | ||
VCL | vinculin | 0.118 | ||
CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.118 | ||
C3 | complement component 3 | 0.117 | ||
MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.116 | ||
ZNF107 | zinc finger protein 107 | 0.116 | ||
ZNF680 | zinc finger protein 680 | 0.115 | Human | |
NOD2 | nucleotide-binding oligomerization domain containing 2 | 0.115 | ||
IL6ST | interleukin 6 signal transducer (gp130, oncostatin M receptor) | 0.115 | ||
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.114 | ||
CCR4 | chemokine (C-C motif) receptor 4 | 0.113 | ||
ARIH2 | ariadne homolog 2 (Drosophila) | 0.113 | ||
PELI1 | pellino homolog 1 (Drosophila) | 0.113 | Mouse | |
TGFBR1 | transforming growth factor, beta receptor 1 | 0.111 | ||
DIABLO | diablo, IAP-binding mitochondrial protein | 0.111 | ||
EP300 | E1A binding protein p300 | 0.110 | ||
TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | 0.109 | Human | |
VCAM1 | vascular cell adhesion molecule 1 | 0.109 | ||
PIAS4 | protein inhibitor of activated STAT, 4 | 0.109 | ||
TAB3 | TGF-beta activated kinase 1/MAP3K7 binding protein 3 | 0.108 | Human | |
MAP2K5 | mitogen-activated protein kinase kinase 5 | 0.108 | ||
RXRA | retinoid X receptor, alpha | 0.107 | ||
S100A2 | S100 calcium binding protein A2 | 0.106 | Human | |
IDO1 | indoleamine 2,3-dioxygenase 1 | 0.105 | ||
GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.104 | ||
ZNF180 | zinc finger protein 180 | 0.104 | ||
HDAC1 | histone deacetylase 1 | 0.104 | Mouse | |
ZNF571 | zinc finger protein 571 | 0.103 | ||
SOCS1 | suppressor of cytokine signaling 1 | 0.102 | ||
STAT4 | signal transducer and activator of transcription 4 | 0.102 | Human | |
MAGEA4 | melanoma antigen family A, 4 | 0.102 | ||
TIFA | TRAF-interacting protein with forkhead-associated domain | 0.102 | Mouse | |
FN1 | fibronectin 1 | 0.102 | ||
MUC1 | mucin 1, cell surface associated | 0.101 | ||
IFNGR1 | interferon gamma receptor 1 | 0.101 | ||
PTEN | phosphatase and tensin homolog | 0.100 | ||
PI3 | peptidase inhibitor 3, skin-derived | 0.100 | ||
BTN3A3 | butyrophilin, subfamily 3, member A3 | 0.100 | ||
PCDHA4 | protocadherin alpha 4 | 0.099 | ||
FCN1 | ficolin (collagen/fibrinogen domain containing) 1 | 0.099 | ||
MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.099 | ||
HDAC7 | histone deacetylase 7 | 0.099 | ||
CXCL13 | chemokine (C-X-C motif) ligand 13 | 0.099 | ||
LIN28B | lin-28 homolog B (C. elegans) | 0.098 | ||
STAT5A | signal transducer and activator of transcription 5A | 0.097 | Human | |
NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.096 | ||
PEA15 | phosphoprotein enriched in astrocytes 15 | 0.096 | ||
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.096 | ||
IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.096 | ||
CAST | calpastatin | 0.095 | ||
CD83 | CD83 molecule | 0.095 | ||
ILK | integrin-linked kinase | 0.095 | ||
BTN3A1 | butyrophilin, subfamily 3, member A1 | 0.094 | ||
SPHK1 | sphingosine kinase 1 | 0.094 | ||
UBA7 | ubiquitin-like modifier activating enzyme 7 | 0.094 | ||
LCK | lymphocyte-specific protein tyrosine kinase | 0.094 | ||
CSF1 | colony stimulating factor 1 (macrophage) | 0.093 | ||
RAP1B | RAP1B, member of RAS oncogene family | 0.093 | ||
BTK | Bruton agammaglobulinemia tyrosine kinase | 0.093 | Mouse | |
UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.092 | ||
ANXA7 | annexin A7 | 0.092 | ||
SNX5 | sorting nexin 5 | 0.092 | ||
DCAF7 | DDB1 and CUL4 associated factor 7 | 0.091 | ||
ZNF12 | zinc finger protein 12 | 0.091 | ||
EMP3 | epithelial membrane protein 3 | 0.091 | ||
CRKL | v-crk sarcoma virus CT10 oncogene homolog (avian)-like | 0.091 | ||
KLF5 | Kruppel-like factor 5 (intestinal) | 0.091 | ||
CXCL6 | chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2) | 0.090 | ||
CLEC10A | C-type lectin domain family 10, member A | 0.090 | ||
UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.090 | ||
STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.090 | ||
PPP1R16A | protein phosphatase 1, regulatory (inhibitor) subunit 16A | 0.090 | ||
CD2 | CD2 molecule | 0.090 | ||
TRIM34 | tripartite motif containing 34 | 0.089 | ||
CAV1 | caveolin 1, caveolae protein, 22kDa | 0.087 | ||
IRAK3 | interleukin-1 receptor-associated kinase 3 | 0.087 | Human | |
UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.087 | ||
MDFI | MyoD family inhibitor | 0.086 | ||
KRT8 | keratin 8 | 0.086 | ||
TRAF4 | TNF receptor-associated factor 4 | 0.086 | Human | |
DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.086 | ||
CCL3 | chemokine (C-C motif) ligand 3 | 0.086 | Human | |
APOL1 | apolipoprotein L, 1 | 0.085 | Human | |
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.085 | ||
CDK9 | cyclin-dependent kinase 9 | 0.084 | ||
TRAFD1 | TRAF-type zinc finger domain containing 1 | 0.084 | ||
RHOA | ras homolog gene family, member A | 0.084 | ||
VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.084 | ||
PLEC | plectin | 0.083 | ||
FBLIM1 | filamin binding LIM protein 1 | 0.083 | Human | |
PTGES | prostaglandin E synthase | 0.083 | ||
IDE | insulin-degrading enzyme | 0.083 | ||
MEFV | Mediterranean fever | 0.083 | ||
RRBP1 | ribosome binding protein 1 homolog 180kDa (dog) | 0.083 | ||
MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | 0.083 | ||
GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 0.082 | ||
ZNF227 | zinc finger protein 227 | 0.082 | ||
LIF | leukemia inhibitory factor (cholinergic differentiation factor) | 0.081 | ||
SAMD9L | sterile alpha motif domain containing 9-like | 0.081 | ||
ARL15 | ADP-ribosylation factor-like 15 | 0.080 | ||
ZNF529 | zinc finger protein 529 | 0.080 | ||
CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.080 | ||
NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.080 | ||
BCL2A1 | BCL2-related protein A1 | 0.080 | ||
UBD | ubiquitin D | 0.080 | ||
NR0B2 | nuclear receptor subfamily 0, group B, member 2 | 0.079 | ||
XPO6 | exportin 6 | 0.078 | ||
MKRN1 | makorin ring finger protein 1 | 0.078 | ||
EFCAB4B | EF-hand calcium binding domain 4B | 0.078 | ||
LAD1 | ladinin 1 | 0.078 | ||
SETD7 | SET domain containing (lysine methyltransferase) 7 | 0.077 | ||
FTL | ferritin, light polypeptide | 0.077 | ||
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.077 | ||
CAPNS1 | calpain, small subunit 1 | 0.077 | ||
GNA15 | guanine nucleotide binding protein (G protein), alpha 15 (Gq class) | 0.076 | ||
RARRES3 | retinoic acid receptor responder (tazarotene induced) 3 | 0.076 | ||
BBS10 | Bardet-Biedl syndrome 10 | 0.076 | ||
ZNF569 | zinc finger protein 569 | 0.075 | ||
SBF1 | SET binding factor 1 | 0.075 | ||
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.075 | ||
IRF4 | interferon regulatory factor 4 | 0.074 | ||
PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.074 | ||
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.074 | ||
AGER | advanced glycosylation end product-specific receptor | 0.073 | ||
SELL | selectin L | 0.073 | ||
MICA | MHC class I polypeptide-related sequence A | 0.073 | ||
PPP2R2B | protein phosphatase 2, regulatory subunit B, beta | 0.073 | ||
USP38 | ubiquitin specific peptidase 38 | 0.073 | ||
IL10 | interleukin 10 | 0.073 | ||
IL18RAP | interleukin 18 receptor accessory protein | 0.073 | ||
PIAS2 | protein inhibitor of activated STAT, 2 | 0.073 | ||
HOXA9 | homeobox A9 | 0.073 | ||
TREM1 | triggering receptor expressed on myeloid cells 1 | 0.073 | ||
SERTAD1 | SERTA domain containing 1 | 0.072 | ||
TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.072 | ||
GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | 0.072 | ||
IGSF6 | immunoglobulin superfamily, member 6 | 0.072 | ||
TJP1 | tight junction protein 1 (zona occludens 1) | 0.072 | ||
IRF3 | interferon regulatory factor 3 | 0.072 | ||
TUBB2B | tubulin, beta 2B | 0.072 | ||
DAZAP2 | DAZ associated protein 2 | 0.071 | ||
CCL11 | chemokine (C-C motif) ligand 11 | 0.071 | Human | |
RNF5 | ring finger protein 5 | 0.071 | ||
CBLC | Cas-Br-M (murine) ecotropic retroviral transforming sequence c | 0.071 | ||
IL1RAP | interleukin 1 receptor accessory protein | 0.071 | ||
EFTUD2 | elongation factor Tu GTP binding domain containing 2 | 0.071 | ||
LAMC2 | laminin, gamma 2 | 0.071 | ||
PYDC2 | pyrin domain containing 2 | 0.070 | ||
GFM1 | G elongation factor, mitochondrial 1 | 0.070 | ||
UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.070 | ||
SOD2 | superoxide dismutase 2, mitochondrial | 0.070 | ||
TRIM22 | tripartite motif containing 22 | 0.070 | ||
IFI16 | interferon, gamma-inducible protein 16 | 0.070 | ||
CD7 | CD7 molecule | 0.070 | ||
HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.070 | ||
TRAF7 | TNF receptor-associated factor 7 | 0.070 | ||
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.069 | ||
JAK1 | Janus kinase 1 | 0.069 | ||
ERBB3 | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 0.069 | ||
RNF185 | ring finger protein 185 | 0.069 | ||
CLEC18C | C-type lectin domain family 18, member C | 0.069 | ||
RAPGEF1 | Rap guanine nucleotide exchange factor (GEF) 1 | 0.069 | ||
TUBB6 | tubulin, beta 6 | 0.069 | ||
ZNF92 | zinc finger protein 92 | 0.069 | Human | |
DLL1 | delta-like 1 (Drosophila) | 0.069 | ||
RNF14 | ring finger protein 14 | 0.068 | ||
GOLGA2 | golgin A2 | 0.068 | ||
CD151 | CD151 molecule (Raph blood group) | 0.068 | ||
PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.067 | ||
ADAP2 | ArfGAP with dual PH domains 2 | 0.067 | ||
KLF2 | Kruppel-like factor 2 (lung) | 0.067 | ||
NCOR2 | nuclear receptor corepressor 2 | 0.067 | ||
SIGLEC1 | sialic acid binding Ig-like lectin 1, sialoadhesin | 0.067 | ||
TRIM21 | tripartite motif containing 21 | 0.067 | Human | |
ZHX1 | zinc fingers and homeoboxes 1 | 0.067 | ||
IFIH1 | interferon induced with helicase C domain 1 | 0.067 | ||
GJB3 | gap junction protein, beta 3, 31kDa | 0.067 | ||
MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.066 | ||
KCNE3 | potassium voltage-gated channel, Isk-related family, member 3 | 0.066 | ||
KYNU | kynureninase | 0.066 | ||
MYOZ1 | myozenin 1 | 0.065 | ||
IGF2 | insulin-like growth factor 2 (somatomedin A) | 0.065 | ||
SMAD5 | SMAD family member 5 | 0.065 | ||
LRP10 | low density lipoprotein receptor-related protein 10 | 0.065 | ||
SELE | selectin E | 0.065 | ||
MAPK6 | mitogen-activated protein kinase 6 | 0.065 | ||
PTPRC | protein tyrosine phosphatase, receptor type, C | 0.064 | ||
CTSB | cathepsin B | 0.064 | ||
CCR3 | chemokine (C-C motif) receptor 3 | 0.064 | ||
MR1 | major histocompatibility complex, class I-related | 0.063 | ||
MARK2 | MAP/microtubule affinity-regulating kinase 2 | 0.063 | ||
RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.063 | ||
CSNK1D | casein kinase 1, delta | 0.063 | ||
SYK | spleen tyrosine kinase | 0.063 | ||
APP | amyloid beta (A4) precursor protein | 0.062 | ||
KRT17 | keratin 17 | 0.062 | ||
JUP | junction plakoglobin | 0.062 | ||
GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 0.062 | ||
CHFR | checkpoint with forkhead and ring finger domains | 0.062 | ||
RNF111 | ring finger protein 111 | 0.062 | ||
CASP7 | caspase 7, apoptosis-related cysteine peptidase | 0.062 | Human | |
PRKRA | protein kinase, interferon-inducible double stranded RNA dependent activator | 0.062 | ||
MARCO | macrophage receptor with collagenous structure | 0.062 | ||
RAD52 | RAD52 homolog (S. cerevisiae) | 0.061 | ||
C9orf89 | chromosome 9 open reading frame 89 | 0.061 | ||
LILRA6 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | 0.061 | ||
TNFRSF13B | tumor necrosis factor receptor superfamily, member 13B | 0.061 | ||
IL15 | interleukin 15 | 0.061 | ||
IL32 | interleukin 32 | 0.061 | ||
TSG101 | tumor susceptibility gene 101 | 0.061 | ||
CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.061 | ||
GABARAPL2 | GABA(A) receptor-associated protein-like 2 | 0.060 | ||
ZNF682 | zinc finger protein 682 | 0.060 | Human | |
KDM2A | lysine (K)-specific demethylase 2A | 0.060 | ||
SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.060 | ||
CAD | carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase | 0.060 | ||
MVP | major vault protein | 0.060 | ||
MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.060 | Human | |
RHOC | ras homolog gene family, member C | 0.059 | ||
DARC | Duffy blood group, chemokine receptor | 0.059 | ||
TNFSF14 | tumor necrosis factor (ligand) superfamily, member 14 | 0.059 | ||
S100P | S100 calcium binding protein P | 0.059 | Human | |
MAFIP | MAFF interacting protein | 0.059 | ||
ZNF263 | zinc finger protein 263 | 0.059 | ||
NOG | noggin | 0.059 | ||
CA12 | carbonic anhydrase XII | 0.058 | ||
ZNF473 | zinc finger protein 473 | 0.058 | ||
EREG | epiregulin | 0.058 | ||
GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 0.058 | ||
OR2AG1 | olfactory receptor, family 2, subfamily AG, member 1 | 0.058 | ||
IL6R | interleukin 6 receptor | 0.058 | ||
USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.057 | ||
CCL1 | chemokine (C-C motif) ligand 1 | 0.057 | Human | |
AIM2 | absent in melanoma 2 | 0.057 | ||
ELK1 | ELK1, member of ETS oncogene family | 0.057 | ||
SHARPIN | SHANK-associated RH domain interactor | 0.057 | ||
TRIM39 | tripartite motif containing 39 | 0.057 | Human | |
SIRT6 | sirtuin 6 | 0.057 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.057 | ||
CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.057 | ||
ZFAND6 | zinc finger, AN1-type domain 6 | 0.056 | ||
SLC15A3 | solute carrier family 15, member 3 | 0.056 | ||
SMPD1 | sphingomyelin phosphodiesterase 1, acid lysosomal | 0.056 | ||
INHBA | inhibin, beta A | 0.056 | ||
PKP3 | plakophilin 3 | 0.056 | ||
PDPK1 | 3-phosphoinositide dependent protein kinase-1 | 0.056 | ||
CH25H | cholesterol 25-hydroxylase | 0.056 | ||
REL | v-rel reticuloendotheliosis viral oncogene homolog (avian) | 0.055 | ||
ZNF140 | zinc finger protein 140 | 0.055 | Human | |
LEF1 | lymphoid enhancer-binding factor 1 | 0.055 | ||
NLRP3 | NLR family, pyrin domain containing 3 | 0.055 | ||
GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.055 | ||
TRIM38 | tripartite motif containing 38 | 0.055 | ||
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.055 | ||
UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.055 | ||
TGIF1 | TGFB-induced factor homeobox 1 | 0.054 | ||
IFITM2 | interferon induced transmembrane protein 2 (1-8D) | 0.054 | ||
LGALS9 | lectin, galactoside-binding, soluble, 9 | 0.054 | ||
AOAH | acyloxyacyl hydrolase (neutrophil) | 0.054 | ||
PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.054 | ||
LILRA1 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 | 0.054 | ||
PTPLAD1 | protein tyrosine phosphatase-like A domain containing 1 | 0.054 | ||
ATXN1L | ataxin 1-like | 0.054 | ||
IL1A | interleukin 1, alpha | 0.053 | Human | |
TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.053 | ||
SPRR2A | small proline-rich protein 2A | 0.053 | ||
RNF181 | ring finger protein 181 | 0.053 | ||
VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C | 0.053 | Human | |
C15orf39 | chromosome 15 open reading frame 39 | 0.053 | ||
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.053 | ||
CD48 | CD48 molecule | 0.053 | ||
ZNF506 | zinc finger protein 506 | 0.053 | Human | |
C1orf9 | chromosome 1 open reading frame 9 | 0.052 | ||
IL18R1 | interleukin 18 receptor 1 | 0.052 | Mouse | |
UBASH3A | ubiquitin associated and SH3 domain containing A | 0.052 | ||
PXN | paxillin | 0.052 | ||
PRKCD | protein kinase C, delta | 0.052 | ||
ATF2 | activating transcription factor 2 | 0.052 | ||
GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.052 | ||
SLAMF7 | SLAM family member 7 | 0.052 | ||
FKBP5 | FK506 binding protein 5 | 0.051 | ||
ANGPT2 | angiopoietin 2 | 0.051 | ||
HSPA6 | heat shock 70kDa protein 6 (HSP70B') | 0.051 | ||
ZNF432 | zinc finger protein 432 | 0.051 | ||
CSTA | cystatin A (stefin A) | 0.051 | ||
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.051 | ||
IL2RA | interleukin 2 receptor, alpha | 0.051 | ||
PAAF1 | proteasomal ATPase-associated factor 1 | 0.051 | ||
TLR7 | toll-like receptor 7 | 0.051 | ||
PYCARD | PYD and CARD domain containing | 0.050 | ||
S100A12 | S100 calcium binding protein A12 | 0.050 | ||
OSMR | oncostatin M receptor | 0.050 | ||
TNFRSF4 | tumor necrosis factor receptor superfamily, member 4 | 0.050 | ||
HSF1 | heat shock transcription factor 1 | 0.050 | ||
RNF4 | ring finger protein 4 | 0.050 | ||
CD63 | CD63 molecule | 0.050 | ||
LRDD | leucine-rich repeats and death domain containing | 0.050 | ||
YAP1 | Yes-associated protein 1 | 0.050 | ||
MIS18BP1 | MIS18 binding protein 1 | 0.050 | ||
PLEKHO1 | pleckstrin homology domain containing, family O member 1 | 0.050 | ||
XDH | xanthine dehydrogenase | 0.050 | ||
MMP12 | matrix metallopeptidase 12 (macrophage elastase) | 0.050 | ||
ADAM15 | ADAM metallopeptidase domain 15 | 0.050 | ||
SQRDL | sulfide quinone reductase-like (yeast) | 0.050 | ||
CSF3 | colony stimulating factor 3 (granulocyte) | 0.049 | ||
SP110 | SP110 nuclear body protein | 0.049 | ||
IL4 | interleukin 4 | 0.049 | ||
CASP8AP2 | caspase 8 associated protein 2 | 0.049 | ||
ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.049 | ||
GSN | gelsolin | 0.049 | ||
STK4 | serine/threonine kinase 4 | 0.049 | ||
MTA3 | metastasis associated 1 family, member 3 | 0.048 | ||
BLNK | B-cell linker | 0.048 | ||
CARD6 | caspase recruitment domain family, member 6 | 0.048 | ||
CXCL16 | chemokine (C-X-C motif) ligand 16 | 0.048 | ||
RNF8 | ring finger protein 8 | 0.048 | ||
ARHGAP21 | Rho GTPase activating protein 21 | 0.048 | ||
RAB2A | RAB2A, member RAS oncogene family | 0.048 | ||
EMP1 | epithelial membrane protein 1 | 0.048 | ||
THBD | thrombomodulin | 0.048 | ||
CISH | cytokine inducible SH2-containing protein | 0.048 | ||
LAMP3 | lysosomal-associated membrane protein 3 | 0.048 | ||
DAB2 | disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila) | 0.048 | ||
TFPI2 | tissue factor pathway inhibitor 2 | 0.048 | ||
HBEGF | heparin-binding EGF-like growth factor | 0.048 | ||
MLKL | mixed lineage kinase domain-like | 0.048 | ||
XAF1 | XIAP associated factor 1 | 0.047 | ||
COL17A1 | collagen, type XVII, alpha 1 | 0.047 | ||
CCNT2 | cyclin T2 | 0.047 | ||
EPHA2 | EPH receptor A2 | 0.047 | ||
SH2D3A | SH2 domain containing 3A | 0.047 | ||
TRIM26 | tripartite motif containing 26 | 0.047 | ||
DBN1 | drebrin 1 | 0.047 | ||
ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.047 | ||
RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 | 0.047 | ||
MBD4 | methyl-CpG binding domain protein 4 | 0.047 | ||
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.047 | ||
ZNF184 | zinc finger protein 184 | 0.047 | ||
GORASP1 | golgi reassembly stacking protein 1, 65kDa | 0.047 | ||
IL18 | interleukin 18 (interferon-gamma-inducing factor) | 0.047 | ||
ZC3HC1 | zinc finger, C3HC-type containing 1 | 0.046 | ||
ACTA1 | actin, alpha 1, skeletal muscle | 0.046 | ||
LY96 | lymphocyte antigen 96 | 0.046 | ||
CCL17 | chemokine (C-C motif) ligand 17 | 0.046 | Human | |
MSC | musculin | 0.046 | ||
SP100 | SP100 nuclear antigen | 0.046 | ||
PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.046 | ||
PELI2 | pellino homolog 2 (Drosophila) | 0.046 | ||
EML2 | echinoderm microtubule associated protein like 2 | 0.046 | ||
OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.046 | ||
TRIM6-TRIM34 | TRIM6-TRIM34 readthrough | 0.046 | ||
C3AR1 | complement component 3a receptor 1 | 0.046 | ||
CCDC50 | coiled-coil domain containing 50 | 0.045 | ||
SH3BGRL3 | SH3 domain binding glutamic acid-rich protein like 3 | 0.045 | ||
SH2D1A | SH2 domain containing 1A | 0.045 | ||
CARD16 | caspase recruitment domain family, member 16 | 0.045 | ||
EBI3 | Epstein-Barr virus induced 3 | 0.045 | ||
RNF213 | ring finger protein 213 | 0.045 | ||
RNF32 | ring finger protein 32 | 0.045 | ||
VNN2 | vanin 2 | 0.045 | ||
SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.045 | ||
LAMB3 | laminin, beta 3 | 0.045 | ||
PPARG | peroxisome proliferator-activated receptor gamma | 0.045 | ||
PINK1 | PTEN induced putative kinase 1 | 0.045 | ||
BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.045 | ||
LCN2 | lipocalin 2 | 0.045 | ||
ZNF224 | zinc finger protein 224 | 0.044 | ||
ZNF100 | zinc finger protein 100 | 0.044 | Human | |
ING2 | inhibitor of growth family, member 2 | 0.044 | ||
NOD1 | nucleotide-binding oligomerization domain containing 1 | 0.044 | ||
KRT6A | keratin 6A | 0.044 | ||
MKRN3 | makorin ring finger protein 3 | 0.044 | ||
CXCR6 | chemokine (C-X-C motif) receptor 6 | 0.044 | ||
CSF2 | colony stimulating factor 2 (granulocyte-macrophage) | 0.044 | ||
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.044 | Mouse | |
CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.043 | ||
UBQLN1 | ubiquilin 1 | 0.043 | ||
IL1RN | interleukin 1 receptor antagonist | 0.043 | Human | |
SRI | sorcin | 0.043 | ||
TNC | tenascin C | 0.043 | ||
CCRL2 | chemokine (C-C motif) receptor-like 2 | 0.043 | ||
TTC14 | tetratricopeptide repeat domain 14 | 0.043 | ||
RGS2 | regulator of G-protein signaling 2, 24kDa | 0.042 | ||
NUCB2 | nucleobindin 2 | 0.042 | ||
PARK2 | parkinson protein 2, E3 ubiquitin protein ligase (parkin) | 0.042 | ||
AXIN1 | axin 1 | 0.042 | ||
GORAB | golgin, RAB6-interacting | 0.042 | ||
CD80 | CD80 molecule | 0.042 | ||
DST | dystonin | 0.042 | ||
WDR26 | WD repeat domain 26 | 0.042 | ||
PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.042 | ||
ELF4 | E74-like factor 4 (ets domain transcription factor) | 0.042 | ||
PRKCZ | protein kinase C, zeta | 0.042 | ||
ACTN1 | actinin, alpha 1 | 0.042 | ||
TRIM9 | tripartite motif containing 9 | 0.042 | ||
FHL3 | four and a half LIM domains 3 | 0.042 | ||
FAM126B | family with sequence similarity 126, member B | 0.042 | ||
NLK | nemo-like kinase | 0.042 | ||
NLRP1 | NLR family, pyrin domain containing 1 | 0.041 | ||
YTHDF3 | YTH domain family, member 3 | 0.041 | ||
TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.041 | ||
CD27 | CD27 molecule | 0.041 | ||
IL21R | interleukin 21 receptor | 0.041 | ||
KRT18 | keratin 18 | 0.041 | ||
HNF4A | hepatocyte nuclear factor 4, alpha | 0.041 | ||
PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.041 | ||
S100A13 | S100 calcium binding protein A13 | 0.041 | ||
EFNB1 | ephrin-B1 | 0.041 | ||
SOX7 | SRY (sex determining region Y)-box 7 | 0.041 | ||
ZNF493 | zinc finger protein 493 | 0.041 | ||
SH2D2A | SH2 domain containing 2A | 0.041 | ||
HCP5 | HLA complex P5 | 0.041 | ||
CD40LG | CD40 ligand | 0.040 | ||
TRIM55 | tripartite motif containing 55 | 0.040 | Human | |
SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | 0.040 | ||
MTRNR2L1 | MT-RNR2-like 1 | 0.040 | ||
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.040 | ||
TNFSF13B | tumor necrosis factor (ligand) superfamily, member 13b | 0.040 | ||
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 | 0.040 | ||
CARD10 | caspase recruitment domain family, member 10 | 0.040 | Human | |
SHB | Src homology 2 domain containing adaptor protein B | 0.040 | ||
AVPR2 | arginine vasopressin receptor 2 | 0.040 | Mouse | |
VMP1 | vacuole membrane protein 1 | 0.040 | ||
PRDM1 | PR domain containing 1, with ZNF domain | 0.040 | ||
GPR109B | G protein-coupled receptor 109B | 0.040 | ||
PRKCQ | protein kinase C, theta | 0.040 | Rat | |
EDAR | ectodysplasin A receptor | 0.040 | ||
GBP5 | guanylate binding protein 5 | 0.040 | ||
G6PD | glucose-6-phosphate dehydrogenase | 0.040 | ||
SLAMF8 | SLAM family member 8 | 0.040 | ||
APOL3 | apolipoprotein L, 3 | 0.040 | ||
RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | 0.040 | ||
TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.040 | ||
BATF | basic leucine zipper transcription factor, ATF-like | 0.039 | ||
SNRNP27 | small nuclear ribonucleoprotein 27kDa (U4/U6.U5) | 0.039 | ||
LMO2 | LIM domain only 2 (rhombotin-like 1) | 0.039 | ||
TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | 0.039 | ||
SASH3 | SAM and SH3 domain containing 3 | 0.039 | ||
LY6D | lymphocyte antigen 6 complex, locus D | 0.039 | ||
RBM12B | RNA binding motif protein 12B | 0.039 | ||
APOL6 | apolipoprotein L, 6 | 0.039 | ||
NOTCH3 | notch 3 | 0.039 | Fly | |
GPR171 | G protein-coupled receptor 171 | 0.039 | ||
ITGB7 | integrin, beta 7 | 0.039 | ||
PRKACA | protein kinase, cAMP-dependent, catalytic, alpha | 0.039 | ||
IL15RA | interleukin 15 receptor, alpha | 0.039 |