IMP: Integrative Multi-species Prediction

2 genes annotated in human

activation of cdc42 gtpase activity

Any process that initiates the activity of the inactive GTPase Cdc42 through the replacement of GDP by GTP.

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Known genes in the process in humanInclude functional analogs

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Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "activation of cdc42 gtpase activity" (in gray)

Name	Description	Probability
ATP7A	ATPase, Cu++ transporting, alpha polypeptide	0.887
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.670
TAF1D	TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa	0.110
SFN	stratifin	0.066
PKP3	plakophilin 3	0.027
FAM190B	family with sequence similarity 190, member B	0.023
CLIP1	CAP-GLY domain containing linker protein 1	0.022
FAM118B	family with sequence similarity 118, member B	0.021
TCEA2	transcription elongation factor A (SII), 2	0.020
C7orf25	chromosome 7 open reading frame 25	0.020
SIGMAR1	sigma non-opioid intracellular receptor 1	0.019
POLB	polymerase (DNA directed), beta	0.019
CEP70	centrosomal protein 70kDa	0.016
MRPL44	mitochondrial ribosomal protein L44	0.016
LAD1	ladinin 1	0.015
ARPC1B	actin related protein 2/3 complex, subunit 1B, 41kDa	0.015
TNS4	tensin 4	0.014
UBAP1	ubiquitin associated protein 1	0.014
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.013
ERRFI1	ERBB receptor feedback inhibitor 1	0.013
TMSB4X	thymosin beta 4, X-linked	0.012
PAK4	p21 protein (Cdc42/Rac)-activated kinase 4	0.012
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.012
PITPNA	phosphatidylinositol transfer protein, alpha	0.012
S100A11	S100 calcium binding protein A11	0.011
ELOVL1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	0.011
JUB	jub, ajuba homolog (Xenopus laevis)	0.011
UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X	0.010
CD151	CD151 molecule (Raph blood group)	0.010
CGN	cingulin	0.010