IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

forebrain generation of neurons

The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "forebrain generation of neurons"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "forebrain generation of neurons" (in gray)

Name	Description	Probability	Func Analog Organism
FGF1	fibroblast growth factor 1 (acidic)	0.999
VEGFA	vascular endothelial growth factor A	0.995
PDZD11	PDZ domain containing 11	0.993
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.993
TAL1	T-cell acute lymphocytic leukemia 1	0.980
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.973
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.952
TCF4	transcription factor 4	0.948
ARRB1	arrestin, beta 1	0.933
HNF4A	hepatocyte nuclear factor 4, alpha	0.930
POU5F1	POU class 5 homeobox 1	0.929
FGF2	fibroblast growth factor 2 (basic)	0.913
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.911
LRP6	low density lipoprotein receptor-related protein 6	0.909	Mouse
FGF10	fibroblast growth factor 10	0.907
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.907
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.905
WNT3A	wingless-type MMTV integration site family, member 3A	0.899	Mouse
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.849
EGFR	epidermal growth factor receptor	0.842
AP2A1	adaptor-related protein complex 2, alpha 1 subunit	0.822
FZD1	frizzled homolog 1 (Drosophila)	0.802
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.795
ADORA2A	adenosine A2a receptor	0.794
FGFR1	fibroblast growth factor receptor 1	0.787	Mouse Rat
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.774
PAX8	paired box 8	0.755
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.709
POU3F2	POU class 3 homeobox 2	0.662
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.650
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.626
RUNX1	runt-related transcription factor 1	0.625
CPE	carboxypeptidase E	0.603
SH3BP4	SH3-domain binding protein 4	0.594
HOXD12	homeobox D12	0.587
ARID1A	AT rich interactive domain 1A (SWI-like)	0.553
PDX1	pancreatic and duodenal homeobox 1	0.545
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.540
TP73	tumor protein p73	0.524
TRIB3	tribbles homolog 3 (Drosophila)	0.522
FGFR2	fibroblast growth factor receptor 2	0.516	Mouse
FGF7	fibroblast growth factor 7	0.514
TCEAL5	transcription elongation factor A (SII)-like 5	0.512
ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	0.504
SH3RF3	SH3 domain containing ring finger 3	0.478
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.465
HOXC8	homeobox C8	0.446
NKX6-1	NK6 homeobox 1	0.438
SOX11	SRY (sex determining region Y)-box 11	0.435
FGFR3	fibroblast growth factor receptor 3	0.430
SIX3	SIX homeobox 3	0.422
FZD8	frizzled homolog 8 (Drosophila)	0.410	Zebrafish
HES2	hairy and enhancer of split 2 (Drosophila)	0.376
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.373
FGF3	fibroblast growth factor 3	0.368
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.367
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.363
PLCG1	phospholipase C, gamma 1	0.352
MPRIP	myosin phosphatase Rho interacting protein	0.335
ARHGAP1	Rho GTPase activating protein 1	0.331
CHN2	chimerin (chimaerin) 2	0.330
FEZF2	FEZ family zinc finger 2	0.307	Zebrafish Mouse
SMAD7	SMAD family member 7	0.305
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.304
PGF	placental growth factor	0.304
TRO	trophinin	0.299
SALL2	sal-like 2 (Drosophila)	0.297
RAX	retina and anterior neural fold homeobox	0.297
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.296	Mouse
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.294
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.291
APC	adenomatous polyposis coli	0.286
POU3F3	POU class 3 homeobox 3	0.283
ALX3	ALX homeobox 3	0.280
SOX1	SRY (sex determining region Y)-box 1	0.280
LHX2	LIM homeobox 2	0.275
OLIG2	oligodendrocyte lineage transcription factor 2	0.260
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.260
LBX1	ladybird homeobox 1	0.251
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.250
QKI	quaking homolog, KH domain RNA binding (mouse)	0.239
ACTL6B	actin-like 6B	0.239
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.234
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.234
NOSTRIN	nitric oxide synthase trafficker	0.232
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.232
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.229
NR5A2	nuclear receptor subfamily 5, group A, member 2	0.228
DLG2	discs, large homolog 2 (Drosophila)	0.228
RAP1A	RAP1A, member of RAS oncogene family	0.225
HNF1B	HNF1 homeobox B	0.224
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.221
CADM4	cell adhesion molecule 4	0.220
PBRM1	polybromo 1	0.219
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.218
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.213
NPAS1	neuronal PAS domain protein 1	0.210
MSX1	msh homeobox 1	0.209
SFRP5	secreted frizzled-related protein 5	0.203
ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)	0.202
NEUROG3	neurogenin 3	0.194	Zebrafish
FOXD3	forkhead box D3	0.192
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.191
AXIN2	axin 2	0.187
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.186
YY1	YY1 transcription factor	0.183
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.183
FRS2	fibroblast growth factor receptor substrate 2	0.182
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.182
NKX2-2	NK2 homeobox 2	0.181
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.180
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.176
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.173
GSK3B	glycogen synthase kinase 3 beta	0.173
DPYSL2	dihydropyrimidinase-like 2	0.172
NKX2-1	NK2 homeobox 1	0.168	Mouse
GBX2	gastrulation brain homeobox 2	0.167	Mouse
DAXX	death-domain associated protein	0.167
SIX6	SIX homeobox 6	0.165
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.163
STK36	serine/threonine kinase 36	0.160
TP63	tumor protein p63	0.159
SH3RF1	SH3 domain containing ring finger 1	0.157
PYY	peptide YY	0.157
FCHO2	FCH domain only 2	0.157
FOXG1	forkhead box G1	0.157	Mouse
TRAF5	TNF receptor-associated factor 5	0.156
BNC2	basonuclin 2	0.154
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.154
DLG3	discs, large homolog 3 (Drosophila)	0.150
ADRB1	adrenergic, beta-1-, receptor	0.144
HMGA2	high mobility group AT-hook 2	0.143
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.141
FGF5	fibroblast growth factor 5	0.139
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.138
FOXA2	forkhead box A2	0.138
VSX1	visual system homeobox 1	0.137
ZFPM1	zinc finger protein, multitype 1	0.135
CDX2	caudal type homeobox 2	0.133
BHLHE23	basic helix-loop-helix family, member e23	0.133
BBS10	Bardet-Biedl syndrome 10	0.132
POU3F1	POU class 3 homeobox 1	0.131
TTYH1	tweety homolog 1 (Drosophila)	0.131
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.130
ASCL1	achaete-scute complex homolog 1 (Drosophila)	0.129
OTP	orthopedia homeobox	0.128	Mouse
PRKCA	protein kinase C, alpha	0.127
WNT10A	wingless-type MMTV integration site family, member 10A	0.124
COPG2	coatomer protein complex, subunit gamma 2	0.124
RCOR1	REST corepressor 1	0.120
PAX7	paired box 7	0.120
DLL3	delta-like 3 (Drosophila)	0.118
FEV	FEV (ETS oncogene family)	0.118
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.115
TLX2	T-cell leukemia homeobox 2	0.115
NOVA2	neuro-oncological ventral antigen 2	0.114
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.112
PTK6	PTK6 protein tyrosine kinase 6	0.111
CCKBR	cholecystokinin B receptor	0.110
PAX6	paired box 6	0.107	Mouse
SCNN1A	sodium channel, nonvoltage-gated 1 alpha	0.107
SIAH1	seven in absentia homolog 1 (Drosophila)	0.106
NRP1	neuropilin 1	0.106	Mouse
HOXD9	homeobox D9	0.105
ADCY8	adenylate cyclase 8 (brain)	0.105
POU4F3	POU class 4 homeobox 3	0.105
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.102
LHX5	LIM homeobox 5	0.102	Mouse
C1QL1	complement component 1, q subcomponent-like 1	0.102
GLIS2	GLIS family zinc finger 2	0.101
DISC1	disrupted in schizophrenia 1	0.099
RARA	retinoic acid receptor, alpha	0.098
MESP1	mesoderm posterior 1 homolog (mouse)	0.098
LHX1	LIM homeobox 1	0.097
SIX5	SIX homeobox 5	0.097
RTKN	rhotekin	0.096
PAX2	paired box 2	0.095
ALX4	ALX homeobox 4	0.095
HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2	0.094
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.094
ABCC8	ATP-binding cassette, sub-family C (CFTR/MRP), member 8	0.094
CELF4	CUGBP, Elav-like family member 4	0.093
HOXB8	homeobox B8	0.093
NAV3	neuron navigator 3	0.093
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.093
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.092
SECISBP2L	SECIS binding protein 2-like	0.092
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.091
MNX1	motor neuron and pancreas homeobox 1	0.090
FGF8	fibroblast growth factor 8 (androgen-induced)	0.089	Rat
RHOC	ras homolog gene family, member C	0.089
ECEL1	endothelin converting enzyme-like 1	0.089
MBD2	methyl-CpG binding domain protein 2	0.088
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.087
LMX1B	LIM homeobox transcription factor 1, beta	0.087
NEUROG1	neurogenin 1	0.086	Zebrafish
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.086
NEUROG2	neurogenin 2	0.086
HES1	hairy and enhancer of split 1, (Drosophila)	0.086
OPRD1	opioid receptor, delta 1	0.085
HOXA3	homeobox A3	0.085
VAX2	ventral anterior homeobox 2	0.084
PEX14	peroxisomal biogenesis factor 14	0.084
RBMS3	RNA binding motif, single stranded interacting protein 3	0.083
TGFB2	transforming growth factor, beta 2	0.083
HIC1	hypermethylated in cancer 1	0.083
TGFB3	transforming growth factor, beta 3	0.082
RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)	0.082
GSX2	GS homeobox 2	0.082	Mouse
TBX1	T-box 1	0.082
FLNB	filamin B, beta	0.082
AR	androgen receptor	0.081
TFAP2B	transcription factor AP-2 beta (activating enhancer binding protein 2 beta)	0.081
NPAS4	neuronal PAS domain protein 4	0.080
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.079
SMAD1	SMAD family member 1	0.079
LENG8	leukocyte receptor cluster (LRC) member 8	0.078
MCC	mutated in colorectal cancers	0.078
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.077
SFRP1	secreted frizzled-related protein 1	0.077
GNAS	GNAS complex locus	0.075
CACNG4	calcium channel, voltage-dependent, gamma subunit 4	0.075
TRAF6	TNF receptor-associated factor 6	0.075
INHBB	inhibin, beta B	0.075
BMP7	bone morphogenetic protein 7	0.075
SSTR5	somatostatin receptor 5	0.074
EMX1	empty spiracles homeobox 1	0.074
LRRK2	leucine-rich repeat kinase 2	0.074
ADARB2	adenosine deaminase, RNA-specific, B2	0.074
PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	0.074
STON2	stonin 2	0.074
BMP2K	BMP2 inducible kinase	0.074
CSNK1E	casein kinase 1, epsilon	0.074
DOCK1	dedicator of cytokinesis 1	0.072
NRG1	neuregulin 1	0.072
SAP30	Sin3A-associated protein, 30kDa	0.072
CRHR1	corticotropin releasing hormone receptor 1	0.072
PITX3	paired-like homeodomain 3	0.072
GRB10	growth factor receptor-bound protein 10	0.071
NKX2-8	NK2 homeobox 8	0.071
OCRL	oculocerebrorenal syndrome of Lowe	0.071
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.071
CTBP2	C-terminal binding protein 2	0.071
NCKAP1	NCK-associated protein 1	0.071
HTR2C	5-hydroxytryptamine (serotonin) receptor 2C	0.070
TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	0.070
KCNRG	potassium channel regulator	0.070
PTEN	phosphatase and tensin homolog	0.070
SOX2	SRY (sex determining region Y)-box 2	0.070	Mouse
PRKCZ	protein kinase C, zeta	0.069
FZD2	frizzled homolog 2 (Drosophila)	0.069
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.069
IRX5	iroquois homeobox 5	0.069
NELL1	NEL-like 1 (chicken)	0.069
FOXL1	forkhead box L1	0.068
PTF1A	pancreas specific transcription factor, 1a	0.068
HOXA11	homeobox A11	0.068
FOXB1	forkhead box B1	0.067
SOX18	SRY (sex determining region Y)-box 18	0.066
ZMYND8	zinc finger, MYND-type containing 8	0.066
MAX	MYC associated factor X	0.066
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.066
ATP2B2	ATPase, Ca++ transporting, plasma membrane 2	0.066
DPYSL5	dihydropyrimidinase-like 5	0.066
MYB	v-myb myeloblastosis viral oncogene homolog (avian)	0.065
PCDH17	protocadherin 17	0.065
CFL1	cofilin 1 (non-muscle)	0.065
ARX	aristaless related homeobox	0.065	Mouse
SOX10	SRY (sex determining region Y)-box 10	0.064
COL13A1	collagen, type XIII, alpha 1	0.064
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.064
HMX2	H6 family homeobox 2	0.064
CALCA	calcitonin-related polypeptide alpha	0.064
FOXF1	forkhead box F1	0.064
POU4F1	POU class 4 homeobox 1	0.063
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.063
MAPK10	mitogen-activated protein kinase 10	0.063
MYT1	myelin transcription factor 1	0.063
CELF3	CUGBP, Elav-like family member 3	0.063
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.062
WNT1	wingless-type MMTV integration site family, member 1	0.062
COL2A1	collagen, type II, alpha 1	0.062
ATXN1	ataxin 1	0.062
APC2	adenomatosis polyposis coli 2	0.061
GATAD2B	GATA zinc finger domain containing 2B	0.061
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.061
TBX2	T-box 2	0.061
HOXD10	homeobox D10	0.061
SOX9	SRY (sex determining region Y)-box 9	0.061
SLIT2	slit homolog 2 (Drosophila)	0.061
GAK	cyclin G associated kinase	0.060
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.060
NFIB	nuclear factor I/B	0.060
FLRT2	fibronectin leucine rich transmembrane protein 2	0.060
POU3F4	POU class 3 homeobox 4	0.060	Mouse
EN1	engrailed homeobox 1	0.059
BMP4	bone morphogenetic protein 4	0.058
DLX5	distal-less homeobox 5	0.058
HLA-DPB1	major histocompatibility complex, class II, DP beta 1	0.058
IRS4	insulin receptor substrate 4	0.057
NCK2	NCK adaptor protein 2	0.057
FAM83D	family with sequence similarity 83, member D	0.056
WT1	Wilms tumor 1	0.056
DLX2	distal-less homeobox 2	0.056	Mouse
EVX1	even-skipped homeobox 1	0.056
NCOR1	nuclear receptor corepressor 1	0.056
IRX4	iroquois homeobox 4	0.056
GSC	goosecoid homeobox	0.055
DLX4	distal-less homeobox 4	0.055
SHANK2	SH3 and multiple ankyrin repeat domains 2	0.055
OTX2	orthodenticle homeobox 2	0.055
CRMP1	collapsin response mediator protein 1	0.055
EIF2C2	eukaryotic translation initiation factor 2C, 2	0.054
MSX2	msh homeobox 2	0.054
TGFBR1	transforming growth factor, beta receptor 1	0.054
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.054	Mouse
HOXC10	homeobox C10	0.054
HEMGN	hemogen	0.053
MSN	moesin	0.053
MECOM	MDS1 and EVI1 complex locus	0.053
NKX2-3	NK2 transcription factor related, locus 3 (Drosophila)	0.053
PBX1	pre-B-cell leukemia homeobox 1	0.053
FOXF2	forkhead box F2	0.053
ADRA2C	adrenergic, alpha-2C-, receptor	0.053
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.053
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.052
HOXB1	homeobox B1	0.052
FAM110C	family with sequence similarity 110, member C	0.052
TWIST1	twist homolog 1 (Drosophila)	0.052
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.052
PAX3	paired box 3	0.052
DLX1	distal-less homeobox 1	0.052	Mouse
CDK5R2	cyclin-dependent kinase 5, regulatory subunit 2 (p39)	0.052
SCNN1G	sodium channel, nonvoltage-gated 1, gamma	0.052
HOXB9	homeobox B9	0.052
GFAP	glial fibrillary acidic protein	0.052
SALL1	sal-like 1 (Drosophila)	0.052	Mouse
CYP26A1	cytochrome P450, family 26, subfamily A, polypeptide 1	0.051
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.051
KRT5	keratin 5	0.051
MEIS2	Meis homeobox 2	0.051
DIO3	deiodinase, iodothyronine, type III	0.051
DCBLD2	discoidin, CUB and LCCL domain containing 2	0.051
PCDH8	protocadherin 8	0.051
APLP1	amyloid beta (A4) precursor-like protein 1	0.050
ATP8	ATP synthase F0 subunit 8	0.050
TBX5	T-box 5	0.050
PPT1	palmitoyl-protein thioesterase 1	0.050
MYOD1	myogenic differentiation 1	0.050
SLC6A1	solute carrier family 6 (neurotransmitter transporter, GABA), member 1	0.050
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.049
HOXD13	homeobox D13	0.049
GATA5	GATA binding protein 5	0.049
CALCR	calcitonin receptor	0.049
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.049
FERMT2	fermitin family member 2	0.048
NCOA1	nuclear receptor coactivator 1	0.048
SEMA6A	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	0.048
ARRDC3	arrestin domain containing 3	0.048
STC2	stanniocalcin 2	0.048
NCOA3	nuclear receptor coactivator 3	0.048
KCNA4	potassium voltage-gated channel, shaker-related subfamily, member 4	0.047
GPER	G protein-coupled estrogen receptor 1	0.047
PRRX1	paired related homeobox 1	0.047
GRB7	growth factor receptor-bound protein 7	0.047
TRPS1	trichorhinophalangeal syndrome I	0.046
PLXNB1	plexin B1	0.046
KIAA0174	KIAA0174	0.046
HOXB5	homeobox B5	0.046
IGF1R	insulin-like growth factor 1 receptor	0.046
HDAC11	histone deacetylase 11	0.046
AGTR1	angiotensin II receptor, type 1	0.046
AMN	amnionless homolog (mouse)	0.046
GNMT	glycine N-methyltransferase	0.046
HOXC12	homeobox C12	0.046
ADAR	adenosine deaminase, RNA-specific	0.046
EN2	engrailed homeobox 2	0.046
WDFY3	WD repeat and FYVE domain containing 3	0.045
ONECUT1	one cut homeobox 1	0.045
MIXL1	Mix1 homeobox-like 1 (Xenopus laevis)	0.045
MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1	0.045
HOXB3	homeobox B3	0.045
TLX3	T-cell leukemia homeobox 3	0.045
WNT5A	wingless-type MMTV integration site family, member 5A	0.045	Mouse
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.045
EFNB2	ephrin-B2	0.045
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.045
DMRT3	doublesex and mab-3 related transcription factor 3	0.044
WSB1	WD repeat and SOCS box containing 1	0.044
COL5A1	collagen, type V, alpha 1	0.044
ZNF609	zinc finger protein 609	0.044
EPHA4	EPH receptor A4	0.044
ZFHX4	zinc finger homeobox 4	0.044
GATA3	GATA binding protein 3	0.044
RIMS4	regulating synaptic membrane exocytosis 4	0.044
HOXC13	homeobox C13	0.044
NMT2	N-myristoyltransferase 2	0.044
FOXA1	forkhead box A1	0.044
TMEM132E	transmembrane protein 132E	0.044
EGF	epidermal growth factor	0.044
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.044
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.043
BICD1	bicaudal D homolog 1 (Drosophila)	0.043
DLG4	discs, large homolog 4 (Drosophila)	0.043
PITX2	paired-like homeodomain 2	0.043
SHOX2	short stature homeobox 2	0.043
OSBP2	oxysterol binding protein 2	0.043
PTHLH	parathyroid hormone-like hormone	0.043
NRP2	neuropilin 2	0.043	Mouse
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.043
HES7	hairy and enhancer of split 7 (Drosophila)	0.043
DHH	desert hedgehog	0.043
RPRML	reprimo-like	0.042
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.042
POMC	proopiomelanocortin	0.042
FHOD1	formin homology 2 domain containing 1	0.042
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.042
FOXN4	forkhead box N4	0.042
NKX3-2	NK3 homeobox 2	0.042
CKAP2L	cytoskeleton associated protein 2-like	0.042
HTR7	5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)	0.042
VSX2	visual system homeobox 2	0.042
SOX21	SRY (sex determining region Y)-box 21	0.042
HOXD4	homeobox D4	0.042
HOXA6	homeobox A6	0.042
ZNF503	zinc finger protein 503	0.041
RALBP1	ralA binding protein 1	0.041
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.041
EZR	ezrin	0.041
GLT8D2	glycosyltransferase 8 domain containing 2	0.041
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.041	Mouse
PIWIL1	piwi-like 1 (Drosophila)	0.041
BARX1	BARX homeobox 1	0.041
SLC16A11	solute carrier family 16, member 11 (monocarboxylic acid transporter 11)	0.041
ACAN	aggrecan	0.041
SLC32A1	solute carrier family 32 (GABA vesicular transporter), member 1	0.041
TNS4	tensin 4	0.040
ELAVL3	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)	0.040
CTGF	connective tissue growth factor	0.040
DRD4	dopamine receptor D4	0.040
NRG2	neuregulin 2	0.040
SOX13	SRY (sex determining region Y)-box 13	0.040
CA10	carbonic anhydrase X	0.040
NT5C3	5'-nucleotidase, cytosolic III	0.040
AVP	arginine vasopressin	0.040
JAG1	jagged 1	0.040
SORBS3	sorbin and SH3 domain containing 3	0.040
HOXB6	homeobox B6	0.040
GAD1	glutamate decarboxylase 1 (brain, 67kDa)	0.040
CRLF1	cytokine receptor-like factor 1	0.040
EPHA3	EPH receptor A3	0.040
MAP2K5	mitogen-activated protein kinase kinase 5	0.040
NECAB2	N-terminal EF-hand calcium binding protein 2	0.039
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.039
NGFR	nerve growth factor receptor	0.039
ITPKA	inositol-trisphosphate 3-kinase A	0.039
PCDH7	protocadherin 7	0.039
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.039
WSCD1	WSC domain containing 1	0.039
CHD7	chromodomain helicase DNA binding protein 7	0.039
PRDM13	PR domain containing 13	0.039
FAM110A	family with sequence similarity 110, member A	0.039
OTOP3	otopetrin 3	0.039
SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	0.039
KLHL35	kelch-like 35 (Drosophila)	0.039
CDH6	cadherin 6, type 2, K-cadherin (fetal kidney)	0.039
PSEN1	presenilin 1	0.039
TLX1	T-cell leukemia homeobox 1	0.038
IRX1	iroquois homeobox 1	0.038
POU2F3	POU class 2 homeobox 3	0.038
CAMK2N2	calcium/calmodulin-dependent protein kinase II inhibitor 2	0.038
FOXL2	forkhead box L2	0.038
DAB2IP	DAB2 interacting protein	0.038
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.038
DCX	doublecortin	0.038
SLITRK5	SLIT and NTRK-like family, member 5	0.038
TNRC6A	trinucleotide repeat containing 6A	0.038
HOXB13	homeobox B13	0.037
SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)	0.037
ZFP28	zinc finger protein 28 homolog (mouse)	0.037
PHF21B	PHD finger protein 21B	0.037
MAG	myelin associated glycoprotein	0.037
RTN4RL2	reticulon 4 receptor-like 2	0.037
SCNN1B	sodium channel, nonvoltage-gated 1, beta	0.037
VEGFC	vascular endothelial growth factor C	0.037
NXPH1	neurexophilin 1	0.037
FGFR4	fibroblast growth factor receptor 4	0.037
MYF6	myogenic factor 6 (herculin)	0.037
GATA4	GATA binding protein 4	0.037
HMX1	H6 family homeobox 1	0.037
GPC3	glypican 3	0.037
HDAC6	histone deacetylase 6	0.037
GSK3A	glycogen synthase kinase 3 alpha	0.037
RFX4	regulatory factor X, 4 (influences HLA class II expression)	0.037
L1CAM	L1 cell adhesion molecule	0.037
TCF7	transcription factor 7 (T-cell specific, HMG-box)	0.036
KAL1	Kallmann syndrome 1 sequence	0.036
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.036
ADORA1	adenosine A1 receptor	0.036
SIM2	single-minded homolog 2 (Drosophila)	0.036
EYA2	eyes absent homolog 2 (Drosophila)	0.036
MAPT	microtubule-associated protein tau	0.036
HRH3	histamine receptor H3	0.036
C1QTNF4	C1q and tumor necrosis factor related protein 4	0.036
DMRT1	doublesex and mab-3 related transcription factor 1	0.036
FOXC1	forkhead box C1	0.036
SIX2	SIX homeobox 2	0.036
MITF	microphthalmia-associated transcription factor	0.036
EMX2	empty spiracles homeobox 2	0.036
DIAPH1	diaphanous homolog 1 (Drosophila)	0.035
SNCAIP	synuclein, alpha interacting protein	0.035
GPRIN1	G protein regulated inducer of neurite outgrowth 1	0.035
SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)	0.035
MAST1	microtubule associated serine/threonine kinase 1	0.035
GJA3	gap junction protein, alpha 3, 46kDa	0.035
EP300	E1A binding protein p300	0.035
CSPG5	chondroitin sulfate proteoglycan 5 (neuroglycan C)	0.035
RUNX2	runt-related transcription factor 2	0.035
VHL	von Hippel-Lindau tumor suppressor	0.035
SHB	Src homology 2 domain containing adaptor protein B	0.035
TBX3	T-box 3	0.035
EFNB1	ephrin-B1	0.035
MAPK4	mitogen-activated protein kinase 4	0.035
LDLR	low density lipoprotein receptor	0.034
NPPC	natriuretic peptide C	0.034
EPHB3	EPH receptor B3	0.034
ICAM5	intercellular adhesion molecule 5, telencephalin	0.034
KLF5	Kruppel-like factor 5 (intestinal)	0.034
ATN1	atrophin 1	0.034
RIPPLY2	ripply2 homolog (zebrafish)	0.034
PHF21A	PHD finger protein 21A	0.034
FAM123B	family with sequence similarity 123B	0.034
VAV2	vav 2 guanine nucleotide exchange factor	0.034
DOK6	docking protein 6	0.034
RSPO2	R-spondin 2 homolog (Xenopus laevis)	0.034
EBF3	early B-cell factor 3	0.034
CRYBA2	crystallin, beta A2	0.034
HOXD3	homeobox D3	0.034
CHD4	chromodomain helicase DNA binding protein 4	0.034
FOXD2	forkhead box D2	0.034
COL4A6	collagen, type IV, alpha 6	0.034
DLC1	deleted in liver cancer 1	0.034
SCTR	secretin receptor	0.034
GDA	guanine deaminase	0.034
KCNK12	potassium channel, subfamily K, member 12	0.033
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.033
HBQ1	hemoglobin, theta 1	0.033
NCS1	neuronal calcium sensor 1	0.033
INSM1	insulinoma-associated 1	0.033
TARBP2	TAR (HIV-1) RNA binding protein 2	0.033
KCNF1	potassium voltage-gated channel, subfamily F, member 1	0.033
SP8	Sp8 transcription factor	0.033
TAOK1	TAO kinase 1	0.033
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.033
IQGAP3	IQ motif containing GTPase activating protein 3	0.033
UBASH3B	ubiquitin associated and SH3 domain containing B	0.033
NPAS3	neuronal PAS domain protein 3	0.033
SOX14	SRY (sex determining region Y)-box 14	0.033
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.033
EGR3	early growth response 3	0.033
NPTXR	neuronal pentraxin receptor	0.033
GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	0.033
FGF20	fibroblast growth factor 20	0.033
COL14A1	collagen, type XIV, alpha 1	0.033
SCUBE1	signal peptide, CUB domain, EGF-like 1	0.033
MAGED1	melanoma antigen family D, 1	0.032
CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	0.032
EPHA8	EPH receptor A8	0.032
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.032
CDH5	cadherin 5, type 2 (vascular endothelium)	0.032
BRSK2	BR serine/threonine kinase 2	0.032
C1orf94	chromosome 1 open reading frame 94	0.032
ATP1B2	ATPase, Na+/K+ transporting, beta 2 polypeptide	0.032
BHLHE22	basic helix-loop-helix family, member e22	0.032
FBXW8	F-box and WD repeat domain containing 8	0.032
BCL2L10	BCL2-like 10 (apoptosis facilitator)	0.032
FAT4	FAT tumor suppressor homolog 4 (Drosophila)	0.032
SP5	Sp5 transcription factor	0.032
PPAP2B	phosphatidic acid phosphatase type 2B	0.032
CDK2AP1	cyclin-dependent kinase 2 associated protein 1	0.032
PLLP	plasmolipin	0.032
TEKT5	tektin 5	0.032
WNT7A	wingless-type MMTV integration site family, member 7A	0.032
CRABP1	cellular retinoic acid binding protein 1	0.032
PHOX2A	paired-like homeobox 2a	0.032
GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	0.032
FABP7	fatty acid binding protein 7, brain	0.032
SCT	secretin	0.032
HCRTR1	hypocretin (orexin) receptor 1	0.032
NLK	nemo-like kinase	0.032
AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	0.032
TIGD3	tigger transposable element derived 3	0.032
ISL1	ISL LIM homeobox 1	0.032
FOXD1	forkhead box D1	0.032
AQP5	aquaporin 5	0.031
UNCX	UNC homeobox	0.031	Mouse
NPAS2	neuronal PAS domain protein 2	0.031
CMTM8	CKLF-like MARVEL transmembrane domain containing 8	0.031
ISL2	ISL LIM homeobox 2	0.031
ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	0.031
LAMA5	laminin, alpha 5	0.031
FBN2	fibrillin 2	0.031
GALR2	galanin receptor 2	0.031
EYA1	eyes absent homolog 1 (Drosophila)	0.031
GPR161	G protein-coupled receptor 161	0.031
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.031
IRX2	iroquois homeobox 2	0.031
PTPRG	protein tyrosine phosphatase, receptor type, G	0.031
ZBTB43	zinc finger and BTB domain containing 43	0.031
ALCAM	activated leukocyte cell adhesion molecule	0.031
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.031
MEIS1	Meis homeobox 1	0.031
MBP	myelin basic protein	0.031
FOXJ1	forkhead box J1	0.031
TH	tyrosine hydroxylase	0.031
NTSR2	neurotensin receptor 2	0.031
SIAH3	seven in absentia homolog 3 (Drosophila)	0.031
ESPN	espin	0.031
COL4A5	collagen, type IV, alpha 5	0.031
GATA6	GATA binding protein 6	0.031
CHD5	chromodomain helicase DNA binding protein 5	0.031
PAQR9	progestin and adipoQ receptor family member IX	0.031
SREBF2	sterol regulatory element binding transcription factor 2	0.031
NDP	Norrie disease (pseudoglioma)	0.031
AUTS2	autism susceptibility candidate 2	0.030
POSTN	periostin, osteoblast specific factor	0.030
NOVA1	neuro-oncological ventral antigen 1	0.030
CNTNAP2	contactin associated protein-like 2	0.030
GHSR	growth hormone secretagogue receptor	0.030
MSI1	musashi homolog 1 (Drosophila)	0.030
NKD1	naked cuticle homolog 1 (Drosophila)	0.030
HAND2	heart and neural crest derivatives expressed 2	0.030
IGFBPL1	insulin-like growth factor binding protein-like 1	0.030
ASCL2	achaete-scute complex homolog 2 (Drosophila)	0.030	Human
EDNRA	endothelin receptor type A	0.030
FGD1	FYVE, RhoGEF and PH domain containing 1	0.030
LMO1	LIM domain only 1 (rhombotin 1)	0.030
HOXC5	homeobox C5	0.030
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.030	Mouse
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.030
FAM5C	family with sequence similarity 5, member C	0.030
IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3	0.030
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.030
OAF	OAF homolog (Drosophila)	0.030
CDH20	cadherin 20, type 2	0.030
FAM19A4	family with sequence similarity 19 (chemokine (C-C motif)-like), member A4	0.030
SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	0.030	Mouse
LHX6	LIM homeobox 6	0.030	Mouse
TOX3	TOX high mobility group box family member 3	0.030
BDNF	brain-derived neurotrophic factor	0.030
MAPK11	mitogen-activated protein kinase 11	0.030
GATAD2A	GATA zinc finger domain containing 2A	0.030
KHDRBS3	KH domain containing, RNA binding, signal transduction associated 3	0.030
NKX6-2	NK6 homeobox 2	0.030
UBE2R2	ubiquitin-conjugating enzyme E2R 2	0.030
PDE10A	phosphodiesterase 10A	0.029
C2orf55	chromosome 2 open reading frame 55	0.029
ENOX1	ecto-NOX disulfide-thiol exchanger 1	0.029
SPAG8	sperm associated antigen 8	0.029
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.029
GSX1	GS homeobox 1	0.029
TBC1D5	TBC1 domain family, member 5	0.029
INA	internexin neuronal intermediate filament protein, alpha	0.029
BAZ2B	bromodomain adjacent to zinc finger domain, 2B	0.029
EYA4	eyes absent homolog 4 (Drosophila)	0.029
CISH	cytokine inducible SH2-containing protein	0.029
BCHE	butyrylcholinesterase	0.029
MYEF2	myelin expression factor 2	0.029
GUCY1A2	guanylate cyclase 1, soluble, alpha 2	0.029
ZMAT3	zinc finger, matrin-type 3	0.029
DMRTA2	DMRT-like family A2	0.029
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.029
SLC18A3	solute carrier family 18 (vesicular acetylcholine), member 3	0.029
NRG3	neuregulin 3	0.029
NEUROD1	neurogenic differentiation 1	0.029
SORCS3	sortilin-related VPS10 domain containing receptor 3	0.029
STC1	stanniocalcin 1	0.029
KCTD1	potassium channel tetramerisation domain containing 1	0.029
VSTM2L	V-set and transmembrane domain containing 2 like	0.029
DLL4	delta-like 4 (Drosophila)	0.028
TGIF1	TGFB-induced factor homeobox 1	0.028
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.028
ALX1	ALX homeobox 1	0.028
FZD10	frizzled homolog 10 (Drosophila)	0.028
SHH	sonic hedgehog	0.028
DMBX1	diencephalon/mesencephalon homeobox 1	0.028
FAM163A	family with sequence similarity 163, member A	0.028
PCSK2	proprotein convertase subtilisin/kexin type 2	0.028
GFI1	growth factor independent 1 transcription repressor	0.028
PRDM12	PR domain containing 12	0.028
OCLN	occludin	0.028
EFNA5	ephrin-A5	0.028
RGS4	regulator of G-protein signaling 4	0.028
RBM24	RNA binding motif protein 24	0.028
PARVA	parvin, alpha	0.028
HOXA13	homeobox A13	0.028
FAM46A	family with sequence similarity 46, member A	0.028
ZKSCAN5	zinc finger with KRAB and SCAN domains 5	0.028
RAB5B	RAB5B, member RAS oncogene family	0.028
ALOX15	arachidonate 15-lipoxygenase	0.028
PTCH1	patched 1	0.028
TRERF1	transcriptional regulating factor 1	0.028
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.028
AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1	0.028
EVL	Enah/Vasp-like	0.028
SETD8	SET domain containing (lysine methyltransferase) 8	0.028
SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	0.028
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.028
LMX1A	LIM homeobox transcription factor 1, alpha	0.028
PANX2	pannexin 2	0.028
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.028
SLC30A3	solute carrier family 30 (zinc transporter), member 3	0.028
SPOCK3	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3	0.028
CYP26C1	cytochrome P450, family 26, subfamily C, polypeptide 1	0.028
ESRP2	epithelial splicing regulatory protein 2	0.028
ONECUT2	one cut homeobox 2	0.028
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.028
LHX9	LIM homeobox 9	0.028
HOXD1	homeobox D1	0.028
BMPR1B	bone morphogenetic protein receptor, type IB	0.028
ARID5B	AT rich interactive domain 5B (MRF1-like)	0.028
CNTFR	ciliary neurotrophic factor receptor	0.028
CCNO	cyclin O	0.028
GGN	gametogenetin	0.028
POU4F2	POU class 4 homeobox 2	0.028
PRSS12	protease, serine, 12 (neurotrypsin, motopsin)	0.028
RIN1	Ras and Rab interactor 1	0.028
OTOP2	otopetrin 2	0.027
PEX5	peroxisomal biogenesis factor 5	0.027
EFNA2	ephrin-A2	0.027
AMELX	amelogenin, X-linked	0.027
FBXL7	F-box and leucine-rich repeat protein 7	0.027
SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.027
PTPRT	protein tyrosine phosphatase, receptor type, T	0.027
TACC1	transforming, acidic coiled-coil containing protein 1	0.027
UNKL	unkempt homolog (Drosophila)-like	0.027
GRIA3	glutamate receptor, ionotrophic, AMPA 3	0.027
KLF7	Kruppel-like factor 7 (ubiquitous)	0.027
HOXD11	homeobox D11	0.027
MYH9	myosin, heavy chain 9, non-muscle	0.027
MAP1B	microtubule-associated protein 1B	0.027
COL3A1	collagen, type III, alpha 1	0.027
MN1	meningioma (disrupted in balanced translocation) 1	0.027
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.027
C19orf26	chromosome 19 open reading frame 26	0.027
ROR1	receptor tyrosine kinase-like orphan receptor 1	0.027
RAB6A	RAB6A, member RAS oncogene family	0.027
KLHDC4	kelch domain containing 4	0.027
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.027
DRD5	dopamine receptor D5	0.027