IMP: Integrative Multi-species Prediction

Homo sapiens

4 genes annotated in human

Multi-species View

t cell tolerance induction

GO:0002517

A process involving any mechanism for tolerance induction in T cells.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "t cell tolerance induction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "t cell tolerance induction" (in gray)

Name	Description	Probability	Func Analog Organism
HLA-G	major histocompatibility complex, class I, G	0.997
HLA-A	major histocompatibility complex, class I, A	0.997	Human
HLA-B	major histocompatibility complex, class I, B	0.996
HLA-C	major histocompatibility complex, class I, C	0.992	Human
LILRA6	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6	0.967
LILRB2	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	0.917
HLA-F	major histocompatibility complex, class I, F	0.879	Human
B2M	beta-2-microglobulin	0.849
LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	0.834	Human
PILRA	paired immunoglobin-like type 2 receptor alpha	0.730
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.690
HLA-E	major histocompatibility complex, class I, E	0.567	Human
LILRA1	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1	0.463	Human
SIGLEC7	sialic acid binding Ig-like lectin 7	0.415
LILRB3	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3	0.292	Human
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.239
TAP1	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	0.221
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.209
IFITM2	interferon induced transmembrane protein 2 (1-8D)	0.151
LILRA2	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2	0.116
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.099
TGFB1	transforming growth factor, beta 1	0.098
HK3	hexokinase 3 (white cell)	0.083
PTAFR	platelet-activating factor receptor	0.078
SLC15A3	solute carrier family 15, member 3	0.065
TAPBP	TAP binding protein (tapasin)	0.052
TGFB3	transforming growth factor, beta 3	0.051
AOAH	acyloxyacyl hydrolase (neutrophil)	0.048
TYMP	thymidine phosphorylase	0.046
FCN1	ficolin (collagen/fibrinogen domain containing) 1	0.044
CD80	CD80 molecule	0.043
CD247	CD247 molecule	0.041
CCR1	chemokine (C-C motif) receptor 1	0.039
SIRPB1	signal-regulatory protein beta 1	0.039
ENG	endoglin	0.035
CD300C	CD300c molecule	0.033
CA12	carbonic anhydrase XII	0.032
LILRA3	leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3	0.031	Human
WIPI1	WD repeat domain, phosphoinositide interacting 1	0.031
CFLAR	CASP8 and FADD-like apoptosis regulator	0.031
TREM1	triggering receptor expressed on myeloid cells 1	0.029
LGALS3BP	lectin, galactoside-binding, soluble, 3 binding protein	0.029
IKZF3	IKAROS family zinc finger 3 (Aiolos)	0.026
CD33	CD33 molecule	0.026
HLA-DRB5	major histocompatibility complex, class II, DR beta 5	0.026
LILRB4	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4	0.025	Human
NLRP3	NLR family, pyrin domain containing 3	0.025
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.025
SNX9	sorting nexin 9	0.025
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.025
EMR1	egf-like module containing, mucin-like, hormone receptor-like 1	0.025
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.024
FSTL1	follistatin-like 1	0.024
TAPBPL	TAP binding protein-like	0.024
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.023
NOD2	nucleotide-binding oligomerization domain containing 2	0.022
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.022
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.021
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.020
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.020
OS9	osteosarcoma amplified 9, endoplasmic reticulum lectin	0.020
TF	transferrin	0.019
FCAR	Fc fragment of IgA, receptor for	0.019	Human
TPP1	tripeptidyl peptidase I	0.019
SNX18	sorting nexin 18	0.019
CD86	CD86 molecule	0.018	Rat
SIGLEC9	sialic acid binding Ig-like lectin 9	0.018
NCK2	NCK adaptor protein 2	0.018
ASGR2	asialoglycoprotein receptor 2	0.017
RASSF4	Ras association (RalGDS/AF-6) domain family member 4	0.017
TLR8	toll-like receptor 8	0.016
HCP5	HLA complex P5	0.016
TMEM176A	transmembrane protein 176A	0.016
PSAP	prosaposin	0.016
LILRA5	leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5	0.016	Human
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.015
PIK3R5	phosphoinositide-3-kinase, regulatory subunit 5	0.015
TGFBR1	transforming growth factor, beta receptor 1	0.015
FPR2	formyl peptide receptor 2	0.015
TNFSF12-TNFSF13	TNFSF12-TNFSF13 readthrough	0.015
VSIG4	V-set and immunoglobulin domain containing 4	0.015
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.014
PECAM1	platelet/endothelial cell adhesion molecule	0.014
MARCO	macrophage receptor with collagenous structure	0.014
APOBR	apolipoprotein B receptor	0.014
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.014
DPEP2	dipeptidase 2	0.013
RNASE3	ribonuclease, RNase A family, 3	0.013
CST3	cystatin C	0.013
FOLR3	folate receptor 3 (gamma)	0.013
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.013
USP38	ubiquitin specific peptidase 38	0.013
SIRPA	signal-regulatory protein alpha	0.013
CASP5	caspase 5, apoptosis-related cysteine peptidase	0.013
BEST1	bestrophin 1	0.013
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1	0.013
SIGLEC5	sialic acid binding Ig-like lectin 5	0.012
P2RX4	purinergic receptor P2X, ligand-gated ion channel, 4	0.012
EPOR	erythropoietin receptor	0.012
HFE	hemochromatosis	0.012	Human
CLEC10A	C-type lectin domain family 10, member A	0.012
AIF1	allograft inflammatory factor 1	0.012
CD101	CD101 molecule	0.012
CD2AP	CD2-associated protein	0.012
CR1	complement component (3b/4b) receptor 1 (Knops blood group)	0.012
SPG20	spastic paraplegia 20 (Troyer syndrome)	0.012
RNASE2	ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)	0.012
NKG7	natural killer cell group 7 sequence	0.012
BIN2	bridging integrator 2	0.012
EMR3	egf-like module containing, mucin-like, hormone receptor-like 3	0.012
IL32	interleukin 32	0.012
USP15	ubiquitin specific peptidase 15	0.012
TUBA1A	tubulin, alpha 1a	0.012
CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	0.011
CD300A	CD300a molecule	0.011
WASL	Wiskott-Aldrich syndrome-like	0.011
AQP9	aquaporin 9	0.011
P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	0.011
PF4	platelet factor 4	0.011
SIGLEC10	sialic acid binding Ig-like lectin 10	0.011
CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	0.011
S100A12	S100 calcium binding protein A12	0.011
CD28	CD28 molecule	0.011
RETN	resistin	0.011
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	0.011
UBASH3B	ubiquitin associated and SH3 domain containing B	0.011
MS4A3	membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)	0.011
KIR3DL2	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	0.011
FCGR2C	Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)	0.011
JAK1	Janus kinase 1	0.011
MVP	major vault protein	0.011
HAMP	hepcidin antimicrobial peptide	0.011
CD1D	CD1d molecule	0.011
HDAC7	histone deacetylase 7	0.010
KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	0.010
CFP	complement factor properdin	0.010
TBXAS1	thromboxane A synthase 1 (platelet)	0.010
FPR1	formyl peptide receptor 1	0.010
KIR2DL1	killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1	0.010
BPI	bactericidal/permeability-increasing protein	0.010
RNASEL	ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)	0.010
ZNF431	zinc finger protein 431	0.010
TRAF7	TNF receptor-associated factor 7	0.010