Process View
The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
In addition to gene-name show these genes:
Click on a gene's description to view its network relationships with genes known to be involved in "ubiquitin dependent protein catabolic process"
Name | Description | Probability | Func Analog Organism | |
---|---|---|---|---|
UBC | ubiquitin C | 1.000 | ||
PSMD4 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 | 1.000 | Yeast Worm | |
SKP1 | S-phase kinase-associated protein 1 | 1.000 | ||
UBE2D2 | ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast) | 1.000 | Human Yeast | |
XIAP | X-linked inhibitor of apoptosis | 1.000 | Human | |
CUL1 | cullin 1 | 1.000 | ||
VCP | valosin containing protein | 1.000 | ||
UBE2D1 | ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast) | 1.000 | ||
UBE2D3 | ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast) | 1.000 | ||
UBE2N | ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) | 1.000 | Mouse | |
RNF11 | ring finger protein 11 | 1.000 | ||
CDC20 | cell division cycle 20 homolog (S. cerevisiae) | 1.000 | ||
UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 1.000 | ||
CDC27 | cell division cycle 27 homolog (S. cerevisiae) | 0.999 | ||
UBQLN1 | ubiquilin 1 | 0.999 | Human | |
SMAD2 | SMAD family member 2 | 0.999 | Human | |
COPS5 | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 0.999 | Fly | |
CUL3 | cullin 3 | 0.999 | ||
RB1 | retinoblastoma 1 | 0.998 | ||
PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.998 | Yeast | |
MDM2 | Mdm2 p53 binding protein homolog (mouse) | 0.997 | ||
RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.996 | ||
PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.996 | ||
TP53 | tumor protein p53 | 0.995 | ||
PSMD1 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 | 0.994 | Yeast | |
PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.993 | Yeast | |
RAC1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 0.989 | ||
SKP2 | S-phase kinase-associated protein 2 (p45) | 0.986 | Mouse | |
SQSTM1 | sequestosome 1 | 0.984 | ||
OTUB1 | OTU domain, ubiquitin aldehyde binding 1 | 0.983 | ||
PSMC1 | proteasome (prosome, macropain) 26S subunit, ATPase, 1 | 0.981 | ||
HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.981 | Yeast | |
ATXN3 | ataxin 3 | 0.980 | Mouse | |
PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 | 0.980 | ||
PSMA1 | proteasome (prosome, macropain) subunit, alpha type, 1 | 0.979 | Yeast | |
PTK2 | PTK2 protein tyrosine kinase 2 | 0.979 | Human Mouse | |
CCNA2 | cyclin A2 | 0.978 | ||
CCNB1 | cyclin B1 | 0.978 | ||
BUB1B | budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 0.978 | Mouse Fly | |
RNF5 | ring finger protein 5 | 0.978 | ||
TRAF6 | TNF receptor-associated factor 6 | 0.977 | ||
ZNRF1 | zinc and ring finger 1 | 0.974 | Mouse | |
BRCA1 | breast cancer 1, early onset | 0.969 | ||
BTRC | beta-transducin repeat containing | 0.969 | ||
ANAPC4 | anaphase promoting complex subunit 4 | 0.967 | ||
PSMC5 | proteasome (prosome, macropain) 26S subunit, ATPase, 5 | 0.966 | ||
FBXW11 | F-box and WD repeat domain containing 11 | 0.966 | ||
USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) | 0.964 | ||
PSMA4 | proteasome (prosome, macropain) subunit, alpha type, 4 | 0.962 | Yeast | |
CDK2 | cyclin-dependent kinase 2 | 0.962 | ||
RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.962 | ||
SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.961 | ||
PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.961 | Yeast Fly | |
SIAH1 | seven in absentia homolog 1 (Drosophila) | 0.960 | ||
PSMA2 | proteasome (prosome, macropain) subunit, alpha type, 2 | 0.959 | Yeast | |
PLK1 | polo-like kinase 1 | 0.958 | ||
CDC16 | cell division cycle 16 homolog (S. cerevisiae) | 0.958 | Yeast Fly | |
PSMC6 | proteasome (prosome, macropain) 26S subunit, ATPase, 6 | 0.954 | Yeast | |
PSME3 | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 0.952 | ||
POMP | proteasome maturation protein | 0.951 | ||
PAK2 | p21 protein (Cdc42/Rac)-activated kinase 2 | 0.948 | ||
UHRF2 | ubiquitin-like with PHD and ring finger domains 2 | 0.945 | ||
CKS1B | CDC28 protein kinase regulatory subunit 1B | 0.940 | Fly | |
UBE3A | ubiquitin protein ligase E3A | 0.939 | Mouse Fly | |
PSMC3 | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 0.936 | Yeast | |
FBXO5 | F-box protein 5 | 0.935 | ||
ITCH | itchy E3 ubiquitin protein ligase homolog (mouse) | 0.934 | ||
MAP3K7 | mitogen-activated protein kinase kinase kinase 7 | 0.934 | ||
PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 | 0.933 | Yeast | |
PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 | 0.932 | ||
PSMD6 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 | 0.927 | Zebrafish | |
UBE2B | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 0.918 | ||
PSMB6 | proteasome (prosome, macropain) subunit, beta type, 6 | 0.917 | Yeast | |
UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.916 | ||
PSMD12 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 | 0.905 | ||
RNF111 | ring finger protein 111 | 0.904 | Mouse | |
SMAD3 | SMAD family member 3 | 0.902 | Human | |
SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.897 | ||
NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.895 | ||
MARCH7 | membrane-associated ring finger (C3HC4) 7 | 0.893 | ||
PSMB3 | proteasome (prosome, macropain) subunit, beta type, 3 | 0.892 | Yeast | |
ARIH2 | ariadne homolog 2 (Drosophila) | 0.888 | ||
TRIM39 | tripartite motif containing 39 | 0.883 | ||
SYVN1 | synovial apoptosis inhibitor 1, synoviolin | 0.882 | ||
YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide | 0.882 | ||
CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.878 | ||
ANAPC11 | anaphase promoting complex subunit 11 | 0.876 | Yeast | |
PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.873 | ||
PSEN1 | presenilin 1 | 0.869 | Mouse | |
HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.863 | Human | |
PSMB7 | proteasome (prosome, macropain) subunit, beta type, 7 | 0.860 | Yeast | |
HSPA8 | heat shock 70kDa protein 8 | 0.857 | ||
TCEB1 | transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) | 0.855 | ||
IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.849 | ||
PSMD8 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | 0.843 | Yeast | |
HSPA4 | heat shock 70kDa protein 4 | 0.835 | ||
PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.825 | ||
PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.824 | Yeast | |
UFD1L | ubiquitin fusion degradation 1 like (yeast) | 0.823 | Worm | |
UBXN7 | UBX domain protein 7 | 0.820 | Yeast | |
PPP5C | protein phosphatase 5, catalytic subunit | 0.817 | ||
FAF2 | Fas associated factor family member 2 | 0.807 | ||
SMAD4 | SMAD family member 4 | 0.806 | Human | |
PSMD13 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 | 0.800 | Yeast | |
MDM4 | Mdm4 p53 binding protein homolog (mouse) | 0.796 | Human | |
PPP2R5C | protein phosphatase 2, regulatory subunit B', gamma | 0.793 | ||
DERL1 | Der1-like domain family, member 1 | 0.793 | ||
ARHGDIA | Rho GDP dissociation inhibitor (GDI) alpha | 0.792 | ||
CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.790 | ||
PSMD7 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 | 0.789 | ||
USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | 0.788 | ||
MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.783 | ||
FBXW2 | F-box and WD repeat domain containing 2 | 0.782 | ||
CDT1 | chromatin licensing and DNA replication factor 1 | 0.777 | ||
SMAD1 | SMAD family member 1 | 0.774 | Human | |
MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.772 | ||
PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | 0.771 | Yeast | |
NFE2L2 | nuclear factor (erythroid-derived 2)-like 2 | 0.769 | ||
COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.768 | ||
NEDD4 | neural precursor cell expressed, developmentally down-regulated 4 | 0.763 | ||
PSMB4 | proteasome (prosome, macropain) subunit, beta type, 4 | 0.759 | Yeast | |
DCUN1D1 | DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae) | 0.757 | ||
BCAR1 | breast cancer anti-estrogen resistance 1 | 0.756 | ||
RFWD2 | ring finger and WD repeat domain 2 | 0.751 | ||
CDC42 | cell division cycle 42 (GTP binding protein, 25kDa) | 0.747 | ||
PPP1CA | protein phosphatase 1, catalytic subunit, alpha isozyme | 0.746 | ||
GSK3B | glycogen synthase kinase 3 beta | 0.739 | Mouse Fly | |
ATXN1 | ataxin 1 | 0.731 | ||
CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.726 | ||
TRIM43 | tripartite motif containing 43 | 0.725 | ||
SSR1 | signal sequence receptor, alpha | 0.724 | ||
RAD23B | RAD23 homolog B (S. cerevisiae) | 0.722 | ||
STAM | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | 0.721 | ||
PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | 0.712 | ||
E2F1 | E2F transcription factor 1 | 0.707 | ||
RNF126 | ring finger protein 126 | 0.698 | ||
ANAPC5 | anaphase promoting complex subunit 5 | 0.696 | ||
DVL3 | dishevelled, dsh homolog 3 (Drosophila) | 0.694 | Human | |
TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase | 0.690 | ||
CDC23 | cell division cycle 23 homolog (S. cerevisiae) | 0.688 | ||
RAD23A | RAD23 homolog A (S. cerevisiae) | 0.679 | ||
ADRM1 | adhesion regulating molecule 1 | 0.667 | ||
HSPA1B | heat shock 70kDa protein 1B | 0.659 | ||
USP9X | ubiquitin specific peptidase 9, X-linked | 0.658 | Fly | |
AXIN1 | axin 1 | 0.652 | Mouse Rat | |
TRIM21 | tripartite motif containing 21 | 0.651 | Human | |
AMFR | autocrine motility factor receptor | 0.648 | ||
PDCD6IP | programmed cell death 6 interacting protein | 0.644 | ||
RNF2 | ring finger protein 2 | 0.640 | ||
SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.637 | ||
MIB1 | mindbomb homolog 1 (Drosophila) | 0.634 | ||
CANX | calnexin | 0.632 | ||
PSMA5 | proteasome (prosome, macropain) subunit, alpha type, 5 | 0.629 | Yeast | |
ANAPC7 | anaphase promoting complex subunit 7 | 0.629 | ||
UBE2M | ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast) | 0.628 | ||
HSPA13 | heat shock protein 70kDa family, member 13 | 0.619 | ||
ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.618 | ||
FBXW7 | F-box and WD repeat domain containing 7 | 0.613 | ||
CDC25A | cell division cycle 25 homolog A (S. pombe) | 0.611 | ||
TSG101 | tumor susceptibility gene 101 | 0.599 | ||
KLHL12 | kelch-like 12 (Drosophila) | 0.592 | Human | |
FBXO7 | F-box protein 7 | 0.591 | ||
RYBP | RING1 and YY1 binding protein | 0.590 | Fly | |
PSME2 | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) | 0.587 | ||
TCEB2 | transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) | 0.587 | ||
CASP8 | caspase 8, apoptosis-related cysteine peptidase | 0.587 | ||
CDC6 | cell division cycle 6 homolog (S. cerevisiae) | 0.586 | ||
PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.575 | Yeast | |
CSNK1E | casein kinase 1, epsilon | 0.570 | Mouse Fly | |
BMI1 | BMI1 polycomb ring finger oncogene | 0.565 | ||
HDAC6 | histone deacetylase 6 | 0.563 | Mouse | |
SOCS1 | suppressor of cytokine signaling 1 | 0.562 | Human | |
SMAD7 | SMAD family member 7 | 0.559 | ||
UBE2R2 | ubiquitin-conjugating enzyme E2R 2 | 0.557 | Human | |
RNF14 | ring finger protein 14 | 0.557 | ||
KPNA3 | karyopherin alpha 3 (importin alpha 4) | 0.543 | ||
BIRC2 | baculoviral IAP repeat containing 2 | 0.540 | ||
PTEN | phosphatase and tensin homolog | 0.536 | ||
DVL1 | dishevelled, dsh homolog 1 (Drosophila) | 0.534 | ||
TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.534 | ||
RBL2 | retinoblastoma-like 2 (p130) | 0.529 | Human | |
UBE2A | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 0.522 | Human Yeast Fly | |
ATF4 | activating transcription factor 4 (tax-responsive enhancer element B67) | 0.521 | ||
EPS15 | epidermal growth factor receptor pathway substrate 15 | 0.517 | ||
HDAC1 | histone deacetylase 1 | 0.510 | ||
COPS4 | COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) | 0.510 | Fly | |
YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 0.510 | ||
AR | androgen receptor | 0.509 | ||
RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.509 | ||
PPP2R1B | protein phosphatase 2, regulatory subunit A, beta | 0.508 | ||
FOXM1 | forkhead box M1 | 0.506 | ||
SNX9 | sorting nexin 9 | 0.502 | ||
SNF8 | SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae) | 0.494 | ||
FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.493 | ||
PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7) | 0.488 | Yeast | |
ATM | ataxia telangiectasia mutated | 0.487 | ||
BRAF | v-raf murine sarcoma viral oncogene homolog B1 | 0.485 | Human | |
SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.485 | ||
AKT1 | v-akt murine thymoma viral oncogene homolog 1 | 0.477 | Mouse | |
STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | 0.470 | ||
HUWE1 | HECT, UBA and WWE domain containing 1 | 0.468 | Human Yeast | |
UBASH3B | ubiquitin associated and SH3 domain containing B | 0.467 | ||
UBE2Z | ubiquitin-conjugating enzyme E2Z | 0.464 | Mouse | |
UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.458 | Human | |
DAXX | death-domain associated protein | 0.456 | ||
CHD4 | chromodomain helicase DNA binding protein 4 | 0.455 | ||
FYN | FYN oncogene related to SRC, FGR, YES | 0.453 | ||
UBE2E1 | ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast) | 0.452 | ||
TRIM27 | tripartite motif containing 27 | 0.451 | Human | |
CCNB2 | cyclin B2 | 0.443 | ||
MAFG | v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) | 0.435 | ||
COPS3 | COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis) | 0.431 | Worm | |
UBE2E2 | ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast) | 0.431 | ||
PSMB5 | proteasome (prosome, macropain) subunit, beta type, 5 | 0.429 | Yeast Mouse | |
DLG1 | discs, large homolog 1 (Drosophila) | 0.424 | ||
PSMD3 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 | 0.421 | ||
CREBBP | CREB binding protein | 0.419 | ||
UBE4B | ubiquitination factor E4B (UFD2 homolog, yeast) | 0.414 | ||
TRIM32 | tripartite motif containing 32 | 0.411 | ||
TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 | 0.409 | ||
UBE2D4 | ubiquitin-conjugating enzyme E2D 4 (putative) | 0.409 | Human Yeast | |
SELS | selenoprotein S | 0.408 | ||
MAD2L2 | MAD2 mitotic arrest deficient-like 2 (yeast) | 0.403 | ||
UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.400 | ||
BABAM1 | BRISC and BRCA1 A complex member 1 | 0.392 | ||
CBX5 | chromobox homolog 5 | 0.392 | ||
PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | 0.391 | Yeast | |
RNF114 | ring finger protein 114 | 0.389 | ||
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.389 | Mouse | |
ADRBK1 | adrenergic, beta, receptor kinase 1 | 0.389 | ||
PRKCA | protein kinase C, alpha | 0.387 | ||
TADA3 | transcriptional adaptor 3 | 0.385 | ||
PTTG1 | pituitary tumor-transforming 1 | 0.381 | ||
DVL2 | dishevelled, dsh homolog 2 (Drosophila) | 0.380 | Human | |
CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.379 | ||
CDC26 | cell division cycle 26 homolog (S. cerevisiae) | 0.375 | ||
WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.373 | ||
FBXO33 | F-box protein 33 | 0.369 | ||
CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.365 | Fly | |
QKI | quaking homolog, KH domain RNA binding (mouse) | 0.364 | ||
RNF20 | ring finger protein 20 | 0.362 | ||
TRIM5 | tripartite motif containing 5 | 0.362 | Human | |
JUN | jun proto-oncogene | 0.359 | ||
PAG1 | phosphoprotein associated with glycosphingolipid microdomains 1 | 0.358 | ||
TRAF1 | TNF receptor-associated factor 1 | 0.357 | ||
UBE2U | ubiquitin-conjugating enzyme E2U (putative) | 0.354 | ||
MARCH5 | membrane-associated ring finger (C3HC4) 5 | 0.354 | ||
BAG3 | BCL2-associated athanogene 3 | 0.351 | ||
PCM1 | pericentriolar material 1 | 0.349 | ||
IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.349 | ||
ACTB | actin, beta | 0.348 | ||
NCAM1 | neural cell adhesion molecule 1 | 0.347 | ||
CHEK2 | CHK2 checkpoint homolog (S. pombe) | 0.346 | ||
BRCA2 | breast cancer 2, early onset | 0.346 | ||
PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.345 | ||
BAG2 | BCL2-associated athanogene 2 | 0.344 | ||
RNF7 | ring finger protein 7 | 0.342 | ||
UBE2C | ubiquitin-conjugating enzyme E2C | 0.339 | ||
NCK2 | NCK adaptor protein 2 | 0.334 | ||
LRRK2 | leucine-rich repeat kinase 2 | 0.332 | Mouse | |
ARAF | v-raf murine sarcoma 3611 viral oncogene homolog | 0.327 | ||
PML | promyelocytic leukemia | 0.320 | ||
PRC1 | protein regulator of cytokinesis 1 | 0.320 | ||
CDC37 | cell division cycle 37 homolog (S. cerevisiae) | 0.317 | ||
CCT8 | chaperonin containing TCP1, subunit 8 (theta) | 0.312 | ||
ARIH1 | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 0.309 | Human Mouse Fly | |
RNF168 | ring finger protein 168 | 0.309 | ||
RNF38 | ring finger protein 38 | 0.308 | ||
NBN | nibrin | 0.307 | ||
PTK2B | PTK2B protein tyrosine kinase 2 beta | 0.305 | ||
RHOA | ras homolog gene family, member A | 0.305 | ||
USP38 | ubiquitin specific peptidase 38 | 0.304 | ||
CDK1 | cyclin-dependent kinase 1 | 0.301 | ||
UBXN1 | UBX domain protein 1 | 0.301 | ||
EP300 | E1A binding protein p300 | 0.300 | ||
CHFR | checkpoint with forkhead and ring finger domains | 0.293 | Human Mouse | |
NBR1 | neighbor of BRCA1 gene 1 | 0.290 | ||
TRAF3 | TNF receptor-associated factor 3 | 0.289 | ||
NPLOC4 | nuclear protein localization 4 homolog (S. cerevisiae) | 0.285 | Yeast | |
RPN1 | ribophorin I | 0.285 | ||
CDCA8 | cell division cycle associated 8 | 0.285 | ||
YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 0.285 | ||
FBXW5 | F-box and WD repeat domain containing 5 | 0.283 | ||
ZNF746 | zinc finger protein 746 | 0.282 | ||
MAVS | mitochondrial antiviral signaling protein | 0.276 | ||
EPOR | erythropoietin receptor | 0.276 | ||
ERCC6 | excision repair cross-complementing rodent repair deficiency, complementation group 6 | 0.275 | ||
FEN1 | flap structure-specific endonuclease 1 | 0.274 | ||
KCTD10 | potassium channel tetramerisation domain containing 10 | 0.274 | Human | |
CSNK1D | casein kinase 1, delta | 0.273 | Mouse Fly | |
TPBG | trophoblast glycoprotein | 0.269 | ||
PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.267 | ||
GFM1 | G elongation factor, mitochondrial 1 | 0.266 | ||
CHEK1 | CHK1 checkpoint homolog (S. pombe) | 0.264 | ||
BFAR | bifunctional apoptosis regulator | 0.263 | ||
COPS8 | COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis) | 0.263 | ||
RNF185 | ring finger protein 185 | 0.263 | Human | |
TP53BP1 | tumor protein p53 binding protein 1 | 0.262 | ||
ZNF496 | zinc finger protein 496 | 0.261 | ||
HSPA1A | heat shock 70kDa protein 1A | 0.259 | ||
CCT4 | chaperonin containing TCP1, subunit 4 (delta) | 0.256 | ||
BBS10 | Bardet-Biedl syndrome 10 | 0.256 | ||
SKIL | SKI-like oncogene | 0.256 | ||
RNF10 | ring finger protein 10 | 0.253 | ||
FBXO3 | F-box protein 3 | 0.251 | ||
UBE2I | ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast) | 0.251 | Rat | |
PJA2 | praja ring finger 2 | 0.247 | ||
SMAD5 | SMAD family member 5 | 0.246 | Human | |
PAK1 | p21 protein (Cdc42/Rac)-activated kinase 1 | 0.246 | ||
HDAC4 | histone deacetylase 4 | 0.245 | ||
ZFAND5 | zinc finger, AN1-type domain 5 | 0.244 | ||
CDC5L | CDC5 cell division cycle 5-like (S. pombe) | 0.244 | ||
USP4 | ubiquitin specific peptidase 4 (proto-oncogene) | 0.244 | Human | |
TPX2 | TPX2, microtubule-associated, homolog (Xenopus laevis) | 0.242 | ||
PKMYT1 | protein kinase, membrane associated tyrosine/threonine 1 | 0.241 | ||
RNF4 | ring finger protein 4 | 0.238 | ||
UBE2L3 | ubiquitin-conjugating enzyme E2L 3 | 0.235 | ||
TRIM8 | tripartite motif containing 8 | 0.234 | Yeast | |
PSEN2 | presenilin 2 (Alzheimer disease 4) | 0.232 | Mouse | |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 0.231 | ||
TRIM41 | tripartite motif containing 41 | 0.231 | Human | |
UBE2H | ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast) | 0.230 | Yeast Mouse | |
TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) | 0.230 | ||
HSPB1 | heat shock 27kDa protein 1 | 0.230 | ||
PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 0.227 | Yeast | |
NCOR1 | nuclear receptor corepressor 1 | 0.227 | ||
PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) | 0.226 | ||
FAS | Fas (TNF receptor superfamily, member 6) | 0.224 | ||
SETDB1 | SET domain, bifurcated 1 | 0.221 | ||
FBXO30 | F-box protein 30 | 0.220 | ||
WNK4 | WNK lysine deficient protein kinase 4 | 0.219 | ||
NEK2 | NIMA (never in mitosis gene a)-related kinase 2 | 0.219 | ||
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.219 | ||
STAG1 | stromal antigen 1 | 0.218 | ||
RNF31 | ring finger protein 31 | 0.218 | ||
TRAF4 | TNF receptor-associated factor 4 | 0.216 | ||
ATP13A2 | ATPase type 13A2 | 0.216 | ||
FUNDC2 | FUN14 domain containing 2 | 0.215 | ||
RANGAP1 | Ran GTPase activating protein 1 | 0.215 | ||
DDIT3 | DNA-damage-inducible transcript 3 | 0.215 | ||
HIPK3 | homeodomain interacting protein kinase 3 | 0.214 | ||
YY1 | YY1 transcription factor | 0.213 | ||
VTA1 | Vps20-associated 1 homolog (S. cerevisiae) | 0.213 | ||
RAF1 | v-raf-1 murine leukemia viral oncogene homolog 1 | 0.212 | Human | |
CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | 0.212 | ||
CUL5 | cullin 5 | 0.212 | ||
SGOL2 | shugoshin-like 2 (S. pombe) | 0.211 | ||
PRNP | prion protein | 0.211 | ||
CEP55 | centrosomal protein 55kDa | 0.210 | ||
HIPK2 | homeodomain interacting protein kinase 2 | 0.210 | ||
HERC2 | hect domain and RLD 2 | 0.210 | ||
VPRBP | Vpr (HIV-1) binding protein | 0.209 | ||
ANXA1 | annexin A1 | 0.208 | ||
GLI1 | GLI family zinc finger 1 | 0.207 | ||
FBXL15 | F-box and leucine-rich repeat protein 15 | 0.207 | ||
LRR1 | leucine rich repeat protein 1 | 0.206 | ||
SNIP1 | Smad nuclear interacting protein 1 | 0.204 | ||
MYC | v-myc myelocytomatosis viral oncogene homolog (avian) | 0.203 | ||
USP15 | ubiquitin specific peptidase 15 | 0.203 | Human | |
NSFL1C | NSFL1 (p97) cofactor (p47) | 0.201 | Yeast | |
WASL | Wiskott-Aldrich syndrome-like | 0.199 | ||
MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.199 | ||
CHMP4B | chromatin modifying protein 4B | 0.198 | ||
ADAM15 | ADAM metallopeptidase domain 15 | 0.195 | ||
DOT1L | DOT1-like, histone H3 methyltransferase (S. cerevisiae) | 0.195 | ||
MYST2 | MYST histone acetyltransferase 2 | 0.195 | Human | |
DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.195 | ||
SORBS3 | sorbin and SH3 domain containing 3 | 0.194 | ||
DZIP3 | DAZ interacting protein 3, zinc finger | 0.191 | Human | |
IER3 | immediate early response 3 | 0.189 | ||
CDC25C | cell division cycle 25 homolog C (S. pombe) | 0.189 | ||
DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | 0.188 | Yeast | |
ZNF263 | zinc finger protein 263 | 0.187 | ||
DTX3L | deltex 3-like (Drosophila) | 0.187 | ||
MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.186 | ||
MALT1 | mucosa associated lymphoid tissue lymphoma translocation gene 1 | 0.184 | ||
CASP3 | caspase 3, apoptosis-related cysteine peptidase | 0.183 | ||
DNM2 | dynamin 2 | 0.183 | ||
NOMO1 | NODAL modulator 1 | 0.183 | ||
ZRANB1 | zinc finger, RAN-binding domain containing 1 | 0.182 | ||
SH3KBP1 | SH3-domain kinase binding protein 1 | 0.181 | ||
OPTN | optineurin | 0.181 | ||
DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.180 | ||
PAIP1 | poly(A) binding protein interacting protein 1 | 0.179 | ||
PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2) | 0.178 | ||
PRPF6 | PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae) | 0.178 | ||
GCLM | glutamate-cysteine ligase, modifier subunit | 0.178 | ||
APC | adenomatous polyposis coli | 0.177 | ||
FLNB | filamin B, beta | 0.177 | ||
MYST1 | MYST histone acetyltransferase 1 | 0.176 | Human | |
CBLB | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 0.175 | Human | |
TBP | TATA box binding protein | 0.173 | ||
ATF3 | activating transcription factor 3 | 0.173 | ||
TFDP1 | transcription factor Dp-1 | 0.172 | ||
NUDCD3 | NudC domain containing 3 | 0.172 | ||
TERF1 | telomeric repeat binding factor (NIMA-interacting) 1 | 0.171 | ||
RNF130 | ring finger protein 130 | 0.171 | ||
UBXN6 | UBX domain protein 6 | 0.170 | ||
ASF1B | ASF1 anti-silencing function 1 homolog B (S. cerevisiae) | 0.170 | ||
MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.166 | ||
BTBD10 | BTB (POZ) domain containing 10 | 0.166 | ||
KIF2C | kinesin family member 2C | 0.166 | ||
ANKRD17 | ankyrin repeat domain 17 | 0.166 | ||
CAND1 | cullin-associated and neddylation-dissociated 1 | 0.165 | ||
UBXN2A | UBX domain protein 2A | 0.164 | ||
CUL4A | cullin 4A | 0.164 | Mouse | |
PPP2R5A | protein phosphatase 2, regulatory subunit B', alpha | 0.164 | Human | |
AXIN2 | axin 2 | 0.163 | ||
MKRN1 | makorin ring finger protein 1 | 0.163 | ||
VHL | von Hippel-Lindau tumor suppressor | 0.163 | ||
PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.161 | ||
BUB1 | budding uninhibited by benzimidazoles 1 homolog (yeast) | 0.160 | Fly | |
CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | 0.159 | ||
MAP3K1 | mitogen-activated protein kinase kinase kinase 1 | 0.159 | Rat | |
BLM | Bloom syndrome, RecQ helicase-like | 0.159 | ||
HGS | hepatocyte growth factor-regulated tyrosine kinase substrate | 0.158 | ||
ATF5 | activating transcription factor 5 | 0.158 | ||
CCDC101 | coiled-coil domain containing 101 | 0.158 | ||
STAM2 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 | 0.158 | ||
AURKB | aurora kinase B | 0.157 | ||
CHAF1A | chromatin assembly factor 1, subunit A (p150) | 0.157 | ||
UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.156 | Mouse | |
GATAD2B | GATA zinc finger domain containing 2B | 0.155 | ||
GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.155 | ||
NCF2 | neutrophil cytosolic factor 2 | 0.155 | ||
SFN | stratifin | 0.154 | ||
CHMP1A | chromatin modifying protein 1A | 0.154 | ||
RAD51 | RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae) | 0.151 | ||
KDM1A | lysine (K)-specific demethylase 1A | 0.151 | ||
PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 | 0.151 | ||
UBQLN2 | ubiquilin 2 | 0.150 | Human | |
CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | 0.150 | ||
SURF4 | surfeit 4 | 0.150 | ||
C11orf58 | chromosome 11 open reading frame 58 | 0.149 | ||
SRSF3 | serine/arginine-rich splicing factor 3 | 0.149 | ||
COPS7A | COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis) | 0.144 | ||
MED15 | mediator complex subunit 15 | 0.144 | ||
TRADD | TNFRSF1A-associated via death domain | 0.144 | ||
DERL2 | Der1-like domain family, member 2 | 0.143 | ||
ORC1 | origin recognition complex, subunit 1 | 0.142 | ||
ANKRD13A | ankyrin repeat domain 13A | 0.142 | ||
MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 0.142 | ||
FBXO4 | F-box protein 4 | 0.141 | ||
PIAS4 | protein inhibitor of activated STAT, 4 | 0.141 | ||
KIF5B | kinesin family member 5B | 0.141 | ||
SHFM1 | split hand/foot malformation (ectrodactyly) type 1 | 0.140 | ||
DNAJC10 | DnaJ (Hsp40) homolog, subfamily C, member 10 | 0.140 | ||
KLHL2 | kelch-like 2, Mayven (Drosophila) | 0.140 | Human | |
SEC24B | SEC24 family, member B (S. cerevisiae) | 0.139 | ||
CDYL | chromodomain protein, Y-like | 0.139 | ||
MKI67 | antigen identified by monoclonal antibody Ki-67 | 0.138 | ||
UBE2K | ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) | 0.138 | Yeast Mouse | |
TDG | thymine-DNA glycosylase | 0.138 | ||
PCGF2 | polycomb group ring finger 2 | 0.136 | ||
PDIA6 | protein disulfide isomerase family A, member 6 | 0.135 | ||
SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.135 | ||
AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 | 0.135 | ||
UCHL3 | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) | 0.135 | ||
MED21 | mediator complex subunit 21 | 0.134 | ||
WWP1 | WW domain containing E3 ubiquitin protein ligase 1 | 0.133 | Human Yeast Mouse | |
GET4 | golgi to ER traffic protein 4 homolog (S. cerevisiae) | 0.133 | ||
RANBP2 | RAN binding protein 2 | 0.131 | ||
BIRC8 | baculoviral IAP repeat containing 8 | 0.131 | Human | |
TRIM23 | tripartite motif containing 23 | 0.131 | ||
SLBP | stem-loop binding protein | 0.131 | ||
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.131 | Human | |
NASP | nuclear autoantigenic sperm protein (histone-binding) | 0.130 | ||
UBE2E3 | ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast) | 0.130 | ||
VCL | vinculin | 0.130 | ||
CDC73 | cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) | 0.129 | ||
EDEM3 | ER degradation enhancer, mannosidase alpha-like 3 | 0.129 | Mouse | |
HLA-B | major histocompatibility complex, class I, B | 0.129 | ||
RHOB | ras homolog gene family, member B | 0.128 | ||
P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.128 | ||
RCHY1 | ring finger and CHY zinc finger domain containing 1 | 0.128 | ||
SCYL2 | SCY1-like 2 (S. cerevisiae) | 0.126 | ||
CDKN2A | cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4) | 0.126 | ||
SNAI1 | snail homolog 1 (Drosophila) | 0.126 | ||
FHL2 | four and a half LIM domains 2 | 0.124 | ||
WDR26 | WD repeat domain 26 | 0.124 | ||
RNF41 | ring finger protein 41 | 0.123 | ||
ATP6AP1 | ATPase, H+ transporting, lysosomal accessory protein 1 | 0.123 | ||
RAD50 | RAD50 homolog (S. cerevisiae) | 0.123 | ||
G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.122 | ||
PPME1 | protein phosphatase methylesterase 1 | 0.122 | ||
TUBB2C | tubulin, beta 2C | 0.121 | ||
RPL11 | ribosomal protein L11 | 0.121 | ||
CUL4B | cullin 4B | 0.120 | ||
KRT15 | keratin 15 | 0.120 | ||
SLC33A1 | solute carrier family 33 (acetyl-CoA transporter), member 1 | 0.120 | ||
KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.119 | ||
EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.119 | ||
H2AFX | H2A histone family, member X | 0.119 | ||
UBE2J1 | ubiquitin-conjugating enzyme E2, J1 (UBC6 homolog, yeast) | 0.119 | ||
TINF2 | TERF1 (TRF1)-interacting nuclear factor 2 | 0.118 | ||
KCTD3 | potassium channel tetramerisation domain containing 3 | 0.117 | ||
HSF1 | heat shock transcription factor 1 | 0.117 | ||
LRSAM1 | leucine rich repeat and sterile alpha motif containing 1 | 0.117 | ||
KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.117 | ||
HIST2H2AC | histone cluster 2, H2ac | 0.117 | ||
RANBP9 | RAN binding protein 9 | 0.116 | ||
RLIM | ring finger protein, LIM domain interacting | 0.116 | Mouse | |
CCNE1 | cyclin E1 | 0.116 | Fly | |
CCND1 | cyclin D1 | 0.116 | ||
TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.115 | ||
DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 0.115 | ||
EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 | 0.115 | ||
HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.114 | ||
STAG2 | stromal antigen 2 | 0.114 | ||
STMN1 | stathmin 1 | 0.114 | ||
SIRT2 | sirtuin 2 | 0.114 | ||
ING2 | inhibitor of growth family, member 2 | 0.114 | ||
UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | 0.113 | ||
SMC3 | structural maintenance of chromosomes 3 | 0.112 | ||
SIRT1 | sirtuin 1 | 0.112 | ||
RBBP5 | retinoblastoma binding protein 5 | 0.112 | ||
PDS5B | PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae) | 0.111 | ||
ZMYND11 | zinc finger, MYND-type containing 11 | 0.110 | ||
DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.110 | Human | |
NDEL1 | nudE nuclear distribution gene E homolog (A. nidulans)-like 1 | 0.110 | ||
NSMCE1 | non-SMC element 1 homolog (S. cerevisiae) | 0.110 | ||
PPIG | peptidylprolyl isomerase G (cyclophilin G) | 0.109 | ||
RING1 | ring finger protein 1 | 0.109 | ||
MYO1C | myosin IC | 0.109 | ||
UBOX5 | U-box domain containing 5 | 0.108 | ||
NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like | 0.108 | ||
MTDH | metadherin | 0.108 | ||
ARHGEF7 | Rho guanine nucleotide exchange factor (GEF) 7 | 0.107 | ||
PDLIM7 | PDZ and LIM domain 7 (enigma) | 0.107 | ||
RDBP | RD RNA binding protein | 0.107 | ||
ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.107 | ||
JAK2 | Janus kinase 2 | 0.107 | ||
PIAS2 | protein inhibitor of activated STAT, 2 | 0.106 | ||
TRIM33 | tripartite motif containing 33 | 0.106 | ||
ARMC7 | armadillo repeat containing 7 | 0.106 | ||
EXOC5 | exocyst complex component 5 | 0.105 | ||
TAF2 | TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa | 0.104 | ||
PRRC2C | proline-rich coiled-coil 2C | 0.104 | ||
LIN28B | lin-28 homolog B (C. elegans) | 0.104 | ||
OXSR1 | oxidative-stress responsive 1 | 0.102 | ||
TROAP | trophinin associated protein (tastin) | 0.102 | ||
CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.101 | ||
SEC63 | SEC63 homolog (S. cerevisiae) | 0.101 | ||
TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.101 | Mouse | |
RNF26 | ring finger protein 26 | 0.101 | ||
RBBP8 | retinoblastoma binding protein 8 | 0.100 | ||
CACYBP | calcyclin binding protein | 0.099 | ||
RIPK2 | receptor-interacting serine-threonine kinase 2 | 0.099 | ||
FADD | Fas (TNFRSF6)-associated via death domain | 0.098 | ||
CUL2 | cullin 2 | 0.098 | Worm | |
DNM1 | dynamin 1 | 0.098 | ||
MYBL2 | v-myb myeloblastosis viral oncogene homolog (avian)-like 2 | 0.097 | ||
TOM1L1 | target of myb1 (chicken)-like 1 | 0.097 | ||
PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.096 | ||
CD2BP2 | CD2 (cytoplasmic tail) binding protein 2 | 0.096 | ||
ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.096 | ||
PAWR | PRKC, apoptosis, WT1, regulator | 0.096 | ||
FN1 | fibronectin 1 | 0.096 | ||
MUL1 | mitochondrial E3 ubiquitin protein ligase 1 | 0.096 | ||
RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.096 | ||
KSR1 | kinase suppressor of ras 1 | 0.095 | Human | |
CAPZB | capping protein (actin filament) muscle Z-line, beta | 0.095 | ||
SNX16 | sorting nexin 16 | 0.095 | ||
ZYG11B | zyg-11 homolog B (C. elegans) | 0.094 | ||
MYO6 | myosin VI | 0.094 | ||
MAPK8 | mitogen-activated protein kinase 8 | 0.094 | ||
CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon | 0.094 | ||
KLF5 | Kruppel-like factor 5 (intestinal) | 0.094 | ||
TNFRSF1A | tumor necrosis factor receptor superfamily, member 1A | 0.093 | ||
MAP2K7 | mitogen-activated protein kinase kinase 7 | 0.093 | ||
DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.093 | ||
MEX3B | mex-3 homolog B (C. elegans) | 0.093 | ||
VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | 0.092 | ||
ASF1A | ASF1 anti-silencing function 1 homolog A (S. cerevisiae) | 0.092 | ||
PHF20L1 | PHD finger protein 20-like 1 | 0.091 | ||
C19orf10 | chromosome 19 open reading frame 10 | 0.091 | ||
SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | 0.090 | ||
GORAB | golgin, RAB6-interacting | 0.090 | ||
SP100 | SP100 nuclear antigen | 0.090 | ||
NEK6 | NIMA (never in mitosis gene a)-related kinase 6 | 0.090 | ||
ANKRD13C | ankyrin repeat domain 13C | 0.089 | ||
WAPAL | wings apart-like homolog (Drosophila) | 0.089 | ||
STAU1 | staufen, RNA binding protein, homolog 1 (Drosophila) | 0.089 | ||
UBE2W | ubiquitin-conjugating enzyme E2W (putative) | 0.089 | Mouse | |
UBD | ubiquitin D | 0.088 | ||
RIPK3 | receptor-interacting serine-threonine kinase 3 | 0.088 | ||
TRIM11 | tripartite motif containing 11 | 0.088 | Human | |
KLHDC5 | kelch domain containing 5 | 0.088 | ||
DCTN4 | dynactin 4 (p62) | 0.088 | ||
TGFB1 | transforming growth factor, beta 1 | 0.087 | ||
PCBP1 | poly(rC) binding protein 1 | 0.087 | Human | |
TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.086 | ||
RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase | 0.086 | ||
ANAPC10 | anaphase promoting complex subunit 10 | 0.086 | Yeast | |
GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 | 0.086 | ||
TRIM37 | tripartite motif containing 37 | 0.086 | ||
ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 | 0.085 | ||
DDOST | dolichyl-diphosphooligosaccharide--protein glycosyltransferase | 0.085 | ||
IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta | 0.085 | ||
EPM2A | epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) | 0.085 | ||
VPS28 | vacuolar protein sorting 28 homolog (S. cerevisiae) | 0.085 | ||
NME2 | non-metastatic cells 2, protein (NM23B) expressed in | 0.085 | ||
EEF1G | eukaryotic translation elongation factor 1 gamma | 0.085 | ||
SKI | v-ski sarcoma viral oncogene homolog (avian) | 0.084 | ||
GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.084 | ||
MBIP | MAP3K12 binding inhibitory protein 1 | 0.084 | ||
CDCA3 | cell division cycle associated 3 | 0.084 | ||
CCDC50 | coiled-coil domain containing 50 | 0.083 | ||
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.083 | Human | |
PPP1R15A | protein phosphatase 1, regulatory (inhibitor) subunit 15A | 0.083 | ||
MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 | 0.083 | ||
PHF21A | PHD finger protein 21A | 0.083 | ||
SYNJ1 | synaptojanin 1 | 0.083 | ||
BBS2 | Bardet-Biedl syndrome 2 | 0.082 | ||
SLC9A3R1 | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 0.082 | ||
SCAF11 | SR-related CTD-associated factor 11 | 0.082 | ||
POLH | polymerase (DNA directed), eta | 0.081 | ||
CCDC6 | coiled-coil domain containing 6 | 0.081 | ||
ESPL1 | extra spindle pole bodies homolog 1 (S. cerevisiae) | 0.081 | ||
LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.081 | ||
HECTD1 | HECT domain containing 1 | 0.081 | Human | |
CFLAR | CASP8 and FADD-like apoptosis regulator | 0.081 | ||
RMND5A | required for meiotic nuclear division 5 homolog A (S. cerevisiae) | 0.081 | ||
GTF2F1 | general transcription factor IIF, polypeptide 1, 74kDa | 0.081 | ||
KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 0.080 | ||
VPS37A | vacuolar protein sorting 37 homolog A (S. cerevisiae) | 0.080 | ||
CSNK1A1 | casein kinase 1, alpha 1 | 0.080 | Fly | |
SLC3A2 | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 0.079 | ||
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.079 | Yeast | |
MAPK9 | mitogen-activated protein kinase 9 | 0.079 | ||
ANAPC16 | anaphase promoting complex subunit 16 | 0.079 | ||
KIF15 | kinesin family member 15 | 0.079 | ||
NEK9 | NIMA (never in mitosis gene a)- related kinase 9 | 0.079 | ||
TMEM33 | transmembrane protein 33 | 0.079 | ||
UBB | ubiquitin B | 0.078 | ||
ILK | integrin-linked kinase | 0.078 | ||
PARP3 | poly (ADP-ribose) polymerase family, member 3 | 0.078 | ||
ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited) | 0.078 | ||
MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 | 0.078 | ||
BRAP | BRCA1 associated protein | 0.078 | ||
TOP3A | topoisomerase (DNA) III alpha | 0.078 | ||
BIRC3 | baculoviral IAP repeat containing 3 | 0.077 | Human | |
CCPG1 | cell cycle progression 1 | 0.077 | ||
MID1 | midline 1 (Opitz/BBB syndrome) | 0.077 | ||
KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.077 | ||
KIAA0232 | KIAA0232 | 0.077 | ||
MDC1 | mediator of DNA-damage checkpoint 1 | 0.076 | ||
OTUD5 | OTU domain containing 5 | 0.076 | ||
RNF40 | ring finger protein 40 | 0.076 | Human Rat | |
EAPP | E2F-associated phosphoprotein | 0.076 | ||
DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | 0.076 | ||
BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 0.076 | Human | |
PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase | 0.076 | ||
HDAC5 | histone deacetylase 5 | 0.076 | ||
SPOP | speckle-type POZ protein | 0.076 | ||
ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.076 | ||
CD44 | CD44 molecule (Indian blood group) | 0.075 | ||
MLL2 | myeloid/lymphoid or mixed-lineage leukemia 2 | 0.075 | ||
SPG20 | spastic paraplegia 20 (Troyer syndrome) | 0.075 | ||
FBXO25 | F-box protein 25 | 0.075 | ||
GRB10 | growth factor receptor-bound protein 10 | 0.075 | ||
NCSTN | nicastrin | 0.075 | ||
NPEPPS | aminopeptidase puromycin sensitive | 0.075 | ||
KBTBD7 | kelch repeat and BTB (POZ) domain containing 7 | 0.075 | ||
BTBD2 | BTB (POZ) domain containing 2 | 0.075 | ||
TMEM173 | transmembrane protein 173 | 0.074 | ||
ATAD2 | ATPase family, AAA domain containing 2 | 0.074 | ||
SMAD9 | SMAD family member 9 | 0.074 | ||
SESN2 | sestrin 2 | 0.074 | ||
GFI1B | growth factor independent 1B transcription repressor | 0.074 | ||
HEXA | hexosaminidase A (alpha polypeptide) | 0.074 | ||
RNF181 | ring finger protein 181 | 0.074 | ||
EMD | emerin | 0.073 | ||
RAB21 | RAB21, member RAS oncogene family | 0.073 | ||
SOCS2 | suppressor of cytokine signaling 2 | 0.073 | Human | |
EIF1 | eukaryotic translation initiation factor 1 | 0.073 | ||
ZNF295 | zinc finger protein 295 | 0.073 | ||
DHX30 | DEAH (Asp-Glu-Ala-His) box polypeptide 30 | 0.072 | ||
DHX16 | DEAH (Asp-Glu-Ala-His) box polypeptide 16 | 0.072 | ||
SOD1 | superoxide dismutase 1, soluble | 0.072 | ||
SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.072 | ||
DTX3 | deltex homolog 3 (Drosophila) | 0.072 | ||
CDKN2AIP | CDKN2A interacting protein | 0.071 | ||
CDC7 | cell division cycle 7 homolog (S. cerevisiae) | 0.071 | ||
DYNC1LI1 | dynein, cytoplasmic 1, light intermediate chain 1 | 0.071 | ||
CDC37L1 | cell division cycle 37 homolog (S. cerevisiae)-like 1 | 0.071 | ||
TRIM63 | tripartite motif containing 63 | 0.070 | Human Mouse | |
PSMF1 | proteasome (prosome, macropain) inhibitor subunit 1 (PI31) | 0.070 | ||
ANAPC1 | anaphase promoting complex subunit 1 | 0.070 | Worm Fly | |
KDM4A | lysine (K)-specific demethylase 4A | 0.070 | ||
RACGAP1 | Rac GTPase activating protein 1 | 0.070 | ||
MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.070 | ||
COPS2 | COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis) | 0.070 | ||
MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.070 | ||
STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.070 | ||
ELL | elongation factor RNA polymerase II | 0.069 | ||
BAG1 | BCL2-associated athanogene | 0.069 | ||
COPG | coatomer protein complex, subunit gamma | 0.069 | ||
MAPT | microtubule-associated protein tau | 0.069 | ||
DEPDC1 | DEP domain containing 1 | 0.069 | ||
MANF | mesencephalic astrocyte-derived neurotrophic factor | 0.069 | ||
FBXO34 | F-box protein 34 | 0.069 | ||
CAPNS1 | calpain, small subunit 1 | 0.069 | ||
ECT2 | epithelial cell transforming sequence 2 oncogene | 0.069 | ||
SNW1 | SNW domain containing 1 | 0.068 | ||
SEC31A | SEC31 homolog A (S. cerevisiae) | 0.068 | ||
DDIT4 | DNA-damage-inducible transcript 4 | 0.068 | ||
TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.068 | ||
VPS25 | vacuolar protein sorting 25 homolog (S. cerevisiae) | 0.068 | Fly | |
MAGEA2 | melanoma antigen family A, 2 | 0.068 | ||
TXNDC5 | thioredoxin domain containing 5 (endoplasmic reticulum) | 0.068 | ||
PPP2R5D | protein phosphatase 2, regulatory subunit B', delta | 0.068 | Human | |
NCF4 | neutrophil cytosolic factor 4, 40kDa | 0.068 | ||
FBXW9 | F-box and WD repeat domain containing 9 | 0.068 | ||
MAGED1 | melanoma antigen family D, 1 | 0.068 | ||
DAPK1 | death-associated protein kinase 1 | 0.068 | ||
BAIAP2 | BAI1-associated protein 2 | 0.068 | ||
RNF166 | ring finger protein 166 | 0.068 | ||
CENPF | centromere protein F, 350/400kDa (mitosin) | 0.067 | ||
RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.067 | ||
HOXA1 | homeobox A1 | 0.067 | ||
CHAF1B | chromatin assembly factor 1, subunit B (p60) | 0.067 | ||
DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 | 0.067 | ||
N4BP1 | NEDD4 binding protein 1 | 0.067 | Mouse | |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 0.067 | ||
MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha | 0.067 | ||
CUL7 | cullin 7 | 0.067 | ||
CASP9 | caspase 9, apoptosis-related cysteine peptidase | 0.067 | ||
PINK1 | PTEN induced putative kinase 1 | 0.066 | Fly | |
BANF1 | barrier to autointegration factor 1 | 0.066 | ||
PRKCD | protein kinase C, delta | 0.066 | ||
APIP | APAF1 interacting protein | 0.066 | ||
MATK | megakaryocyte-associated tyrosine kinase | 0.066 | Human | |
ERLEC1 | endoplasmic reticulum lectin 1 | 0.066 | ||
MBD1 | methyl-CpG binding domain protein 1 | 0.066 | ||
APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.066 | ||
MBD4 | methyl-CpG binding domain protein 4 | 0.066 | ||
RAB18 | RAB18, member RAS oncogene family | 0.066 | ||
UBAP1 | ubiquitin associated protein 1 | 0.065 | ||
UBR1 | ubiquitin protein ligase E3 component n-recognin 1 | 0.065 | Mouse | |
RC3H2 | ring finger and CCCH-type domains 2 | 0.065 | ||
MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 | 0.065 | ||
SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.065 | ||
SEC61G | Sec61 gamma subunit | 0.065 | ||
DNAJB11 | DnaJ (Hsp40) homolog, subfamily B, member 11 | 0.065 | ||
GTSE1 | G-2 and S-phase expressed 1 | 0.065 | ||
XAB2 | XPA binding protein 2 | 0.065 | ||
UBE3C | ubiquitin protein ligase E3C | 0.065 | Yeast Worm | |
NLK | nemo-like kinase | 0.065 | ||
PNPLA8 | patatin-like phospholipase domain containing 8 | 0.064 |