IMP: Integrative Multi-species Prediction

Homo sapiens

27 genes annotated in human

Multi-species View

regulation of mitotic sister chromatid segregation

GO:0033047

Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of mitotic sister chromatid segregation"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of mitotic sister chromatid segregation" (in gray)

Name	Description	Probability	Func Analog Organism
CDC20	cell division cycle 20 homolog (S. cerevisiae)	1.000	Yeast Worm Fly
BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	0.999	Mouse Fly
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.994
CDK2	cyclin-dependent kinase 2	0.973
CCNA2	cyclin A2	0.958
ANAPC7	anaphase promoting complex subunit 7	0.868
ANAPC4	anaphase promoting complex subunit 4	0.859
RB1	retinoblastoma 1	0.835
CCNB1	cyclin B1	0.814
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.707	Fly
MAD2L1	MAD2 mitotic arrest deficient-like 1 (yeast)	0.680
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.532
RBL1	retinoblastoma-like 1 (p107)	0.520	Human
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.518
AURKB	aurora kinase B	0.514
FBXO5	F-box protein 5	0.489
SMC6	structural maintenance of chromosomes 6	0.473
PLK1	polo-like kinase 1	0.420
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.419
ANAPC11	anaphase promoting complex subunit 11	0.412
NDC80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.368
SKA1	spindle and kinetochore associated complex subunit 1	0.365
E2F1	E2F transcription factor 1	0.345
SKP2	S-phase kinase-associated protein 2 (p45)	0.313
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.307
ORC1	origin recognition complex, subunit 1	0.305
CUL2	cullin 2	0.303	Worm
CDKN3	cyclin-dependent kinase inhibitor 3	0.295
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.278
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.276
CDC26	cell division cycle 26 homolog (S. cerevisiae)	0.275
MKI67	antigen identified by monoclonal antibody Ki-67	0.264
DEPDC1	DEP domain containing 1	0.262
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.260
BRCA1	breast cancer 1, early onset	0.258
CASC5	cancer susceptibility candidate 5	0.243
SMC4	structural maintenance of chromosomes 4	0.237
MYBL2	v-myb myeloblastosis viral oncogene homolog (avian)-like 2	0.188
PRC1	protein regulator of cytokinesis 1	0.172
BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)	0.170	Worm Fly
CCNB2	cyclin B2	0.168
CDT1	chromatin licensing and DNA replication factor 1	0.161
FOXM1	forkhead box M1	0.154
BIRC5	baculoviral IAP repeat containing 5	0.153
TFDP1	transcription factor Dp-1	0.151
ATAD2	ATPase family, AAA domain containing 2	0.145
CDCA8	cell division cycle associated 8	0.140
CBX5	chromobox homolog 5	0.138
VHL	von Hippel-Lindau tumor suppressor	0.133
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.133
ANAPC5	anaphase promoting complex subunit 5	0.130
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.128
ZWINT	ZW10 interactor	0.125
SMC3	structural maintenance of chromosomes 3	0.124
CDK1	cyclin-dependent kinase 1	0.119
CENPE	centromere protein E, 312kDa	0.116
CEP55	centrosomal protein 55kDa	0.116
STIL	SCL/TAL1 interrupting locus	0.116
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.116
STAG1	stromal antigen 1	0.113
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.102
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.099
INCENP	inner centromere protein antigens 135/155kDa	0.097
CD44	CD44 molecule (Indian blood group)	0.094
SKA2	spindle and kinetochore associated complex subunit 2	0.093
NUSAP1	nucleolar and spindle associated protein 1	0.092
CUL1	cullin 1	0.091
SPC25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.091
KIF2C	kinesin family member 2C	0.091
RAD21	RAD21 homolog (S. pombe)	0.089
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.080
PSMD2	proteasome (prosome, macropain) 26S subunit, non-ATPase, 2	0.080
FANCI	Fanconi anemia, complementation group I	0.077
SKA3	spindle and kinetochore associated complex subunit 3	0.076
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.075
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.074
PTTG1	pituitary tumor-transforming 1	0.074
CENPF	centromere protein F, 350/400kDa (mitosin)	0.074
SPC24	SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.071
KIF11	kinesin family member 11	0.071
GTSE1	G-2 and S-phase expressed 1	0.071
NCAPG2	non-SMC condensin II complex, subunit G2	0.069
NSMCE1	non-SMC element 1 homolog (S. cerevisiae)	0.069
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.066
KIF14	kinesin family member 14	0.065
BRCA2	breast cancer 2, early onset	0.065
TCEB1	transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)	0.064	Worm
DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	0.062
TERF1	telomeric repeat binding factor (NIMA-interacting) 1	0.061
KIF18A	kinesin family member 18A	0.061
NUF2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.060
TROAP	trophinin associated protein (tastin)	0.059
SGOL2	shugoshin-like 2 (S. pombe)	0.059
ZW10	ZW10, kinetochore associated, homolog (Drosophila)	0.058
SKP1	S-phase kinase-associated protein 1	0.057
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.055
ANAPC1	anaphase promoting complex subunit 1	0.055	Worm
HERC2	hect domain and RLD 2	0.052
TTK	TTK protein kinase	0.051	Yeast
CUL4A	cullin 4A	0.050
SGOL1	shugoshin-like 1 (S. pombe)	0.049
LRR1	leucine rich repeat protein 1	0.049
CCDC99	coiled-coil domain containing 99	0.048
TBC1D10A	TBC1 domain family, member 10A	0.048
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.048
CDCA3	cell division cycle associated 3	0.046
RBBP8	retinoblastoma binding protein 8	0.046
PLK4	polo-like kinase 4	0.045
NCAPG	non-SMC condensin I complex, subunit G	0.045
PPP2CB	protein phosphatase 2, catalytic subunit, beta isozyme	0.045
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.042
TERF2IP	telomeric repeat binding factor 2, interacting protein	0.040
NEK9	NIMA (never in mitosis gene a)- related kinase 9	0.040
TINF2	TERF1 (TRF1)-interacting nuclear factor 2	0.038
C13orf34	chromosome 13 open reading frame 34	0.038
ANLN	anillin, actin binding protein	0.038
CDC16	cell division cycle 16 homolog (S. cerevisiae)	0.038	Fly
NCAPH	non-SMC condensin I complex, subunit H	0.037
SIRT2	sirtuin 2	0.036
MELK	maternal embryonic leucine zipper kinase	0.035
PARP3	poly (ADP-ribose) polymerase family, member 3	0.035
RAD51AP1	RAD51 associated protein 1	0.034
E2F4	E2F transcription factor 4, p107/p130-binding	0.034
COPS5	COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)	0.034
PIN1	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	0.033
MAD2L2	MAD2 mitotic arrest deficient-like 2 (yeast)	0.033
RAD51	RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)	0.033
FYN	FYN oncogene related to SRC, FGR, YES	0.033
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.033
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.032
COPS4	COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)	0.031
COMMD1	copper metabolism (Murr1) domain containing 1	0.031
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.031
SPAG5	sperm associated antigen 5	0.030
RACGAP1	Rac GTPase activating protein 1	0.030
DSN1	DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)	0.029
RAD54L	RAD54-like (S. cerevisiae)	0.029
CCNE2	cyclin E2	0.028	Fly
LIN54	lin-54 homolog (C. elegans)	0.028
CDC45	cell division cycle 45 homolog (S. cerevisiae)	0.028
RRM2	ribonucleotide reductase M2	0.028
RBL2	retinoblastoma-like 2 (p130)	0.028	Human
FXR2	fragile X mental retardation, autosomal homolog 2	0.027
KIF20A	kinesin family member 20A	0.027
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.027
PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha	0.026
PPME1	protein phosphatase methylesterase 1	0.026
CKS2	CDC28 protein kinase regulatory subunit 2	0.026
LIN52	lin-52 homolog (C. elegans)	0.026
HJURP	Holliday junction recognition protein	0.025
PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6	0.024
CCNF	cyclin F	0.024
MIS18BP1	MIS18 binding protein 1	0.024
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.024
ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.023
MYH9	myosin, heavy chain 9, non-muscle	0.023
NBN	nibrin	0.023
MASTL	microtubule associated serine/threonine kinase-like	0.023
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.023
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.023	Worm
TRIP13	thyroid hormone receptor interactor 13	0.022
FAM64A	family with sequence similarity 64, member A	0.022
E2F5	E2F transcription factor 5, p130-binding	0.022
ANKRD52	ankyrin repeat domain 52	0.022
POLQ	polymerase (DNA directed), theta	0.022
AXIN1	axin 1	0.022
UHRF1	ubiquitin-like with PHD and ring finger domains 1	0.022
RAD52	RAD52 homolog (S. cerevisiae)	0.021
PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	0.021
PRRC2C	proline-rich coiled-coil 2C	0.021
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.021
POLR2K	polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa	0.020
IGF1R	insulin-like growth factor 1 receptor	0.020
SMC2	structural maintenance of chromosomes 2	0.020
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.020
PSMC1	proteasome (prosome, macropain) 26S subunit, ATPase, 1	0.020
C19orf39	chromosome 19 open reading frame 39	0.019
TYMS	thymidylate synthetase	0.019
CENPQ	centromere protein Q	0.019
CDC25C	cell division cycle 25 homolog C (S. pombe)	0.019
TOP3A	topoisomerase (DNA) III alpha	0.019
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.019
UBE2S	ubiquitin-conjugating enzyme E2S	0.018
PSMD13	proteasome (prosome, macropain) 26S subunit, non-ATPase, 13	0.018
TMEM194A	transmembrane protein 194A	0.018
LIN9	lin-9 homolog (C. elegans)	0.018
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.018
ARIH2	ariadne homolog 2 (Drosophila)	0.018
GSK3B	glycogen synthase kinase 3 beta	0.018	Fly
DONSON	downstream neighbor of SON	0.018
CUL5	cullin 5	0.018
USP49	ubiquitin specific peptidase 49	0.018	Human
CCNE1	cyclin E1	0.018	Fly
KIF15	kinesin family member 15	0.017
USP44	ubiquitin specific peptidase 44	0.017
CLSPN	claspin	0.017
CDC23	cell division cycle 23 homolog (S. cerevisiae)	0.017
POMP	proteasome maturation protein	0.017
HAUS1	HAUS augmin-like complex, subunit 1	0.017
HIST1H1E	histone cluster 1, H1e	0.017
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.017
MYST1	MYST histone acetyltransferase 1	0.017
EXO1	exonuclease 1	0.017
AXIN2	axin 2	0.016
DCLRE1C	DNA cross-link repair 1C	0.016
EHD1	EH-domain containing 1	0.016
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.016
PRNP	prion protein	0.016
KDM4A	lysine (K)-specific demethylase 4A	0.016
CHEK1	CHK1 checkpoint homolog (S. pombe)	0.015
PTEN	phosphatase and tensin homolog	0.015
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.015
PXN	paxillin	0.015
EML4	echinoderm microtubule associated protein like 4	0.015
PPP2R5D	protein phosphatase 2, regulatory subunit B', delta	0.015
PTK2	PTK2 protein tyrosine kinase 2	0.015
PFDN4	prefoldin subunit 4	0.015
NSMCE2	non-SMC element 2, MMS21 homolog (S. cerevisiae)	0.015
RAD51L1	RAD51-like 1 (S. cerevisiae)	0.015
TP53BP1	tumor protein p53 binding protein 1	0.014
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.014
HIST1H1B	histone cluster 1, H1b	0.014
RIF1	RAP1 interacting factor homolog (yeast)	0.014
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.014
KIF4A	kinesin family member 4A	0.014
SERTAD4	SERTA domain containing 4	0.014
EML2	echinoderm microtubule associated protein like 2	0.014
PSMB1	proteasome (prosome, macropain) subunit, beta type, 1	0.014
EPM2A	epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)	0.014
DTL	denticleless homolog (Drosophila)	0.014
CCND3	cyclin D3	0.014
HIST1H3D	histone cluster 1, H3d	0.013
MAD1L1	MAD1 mitotic arrest deficient-like 1 (yeast)	0.013
NEIL3	nei endonuclease VIII-like 3 (E. coli)	0.013
KIFC1	kinesin family member C1	0.013
AURKA	aurora kinase A	0.013
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.013
C18orf21	chromosome 18 open reading frame 21	0.013
PSMD9	proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	0.013
RHOG	ras homolog gene family, member G (rho G)	0.013
BAG2	BCL2-associated athanogene 2	0.013
LMNA	lamin A/C	0.013
HIST1H2AB	histone cluster 1, H2ab	0.013
RAD51C	RAD51 homolog C (S. cerevisiae)	0.013
HIST1H2AM	histone cluster 1, H2am	0.013
BLM	Bloom syndrome, RecQ helicase-like	0.013
RECQL4	RecQ protein-like 4	0.013
SH2B3	SH2B adaptor protein 3	0.013
SOCS2	suppressor of cytokine signaling 2	0.012
TOR1AIP2	torsin A interacting protein 2	0.012
HAUS3	HAUS augmin-like complex, subunit 3	0.012
KLHL7	kelch-like 7 (Drosophila)	0.012
BTRC	beta-transducin repeat containing	0.012
GRB10	growth factor receptor-bound protein 10	0.012
ANAPC16	anaphase promoting complex subunit 16	0.012
HELLS	helicase, lymphoid-specific	0.012
OTUB1	OTU domain, ubiquitin aldehyde binding 1	0.012
HIST1H4F	histone cluster 1, H4f	0.011
ZNF367	zinc finger protein 367	0.011
KIF18B	kinesin family member 18B	0.011
CCDC101	coiled-coil domain containing 101	0.011
EZR	ezrin	0.011	Fly
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.011
CEP152	centrosomal protein 152kDa	0.011
NCAPH2	non-SMC condensin II complex, subunit H2	0.011
ADAM9	ADAM metallopeptidase domain 9	0.011
DNAJC9	DnaJ (Hsp40) homolog, subfamily C, member 9	0.011
SHFM1	split hand/foot malformation (ectrodactyly) type 1	0.011
DYNC1I2	dynein, cytoplasmic 1, intermediate chain 2	0.011
L3MBTL1	l(3)mbt-like 1 (Drosophila)	0.011
UBASH3B	ubiquitin associated and SH3 domain containing B	0.011
KIF20B	kinesin family member 20B	0.011
ATMIN	ATM interactor	0.011
C12orf48	chromosome 12 open reading frame 48	0.011
FANCA	Fanconi anemia, complementation group A	0.011
MAD2L1BP	MAD2L1 binding protein	0.011
WDR62	WD repeat domain 62	0.011
TK1	thymidine kinase 1, soluble	0.011
ADRB2	adrenergic, beta-2-, receptor, surface	0.011
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.010
MYO1C	myosin IC	0.010
BRPF1	bromodomain and PHD finger containing, 1	0.010
USP9X	ubiquitin specific peptidase 9, X-linked	0.010
NKAP	NFKB activating protein	0.010
ERCC6L	excision repair cross-complementing rodent repair deficiency, complementation group 6-like	0.010
CAND1	cullin-associated and neddylation-dissociated 1	0.010
MAPRE3	microtubule-associated protein, RP/EB family, member 3	0.010
KDM5C	lysine (K)-specific demethylase 5C	0.010
C13orf27	chromosome 13 open reading frame 27	0.010
NCAPD2	non-SMC condensin I complex, subunit D2	0.010