IMP: Integrative Multi-species Prediction

Homo sapiens

17 genes annotated in human

primary alcohol metabolic process

The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "primary alcohol metabolic process"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "primary alcohol metabolic process" (in gray)

Name	Description	Probability	Func Analog Organism
AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)	1.000	Human
AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)	1.000	Human
AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)	0.999
TTR	transthyretin	0.881
ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide	0.843
SOD1	superoxide dismutase 1, soluble	0.610
HADHB	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit	0.426
SCP2	sterol carrier protein 2	0.353
PRDX1	peroxiredoxin 1	0.337
PHYH	phytanoyl-CoA 2-hydroxylase	0.330
CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	0.240
BDH2	3-hydroxybutyrate dehydrogenase, type 2	0.199
HADH	hydroxyacyl-CoA dehydrogenase	0.194
ETFDH	electron-transferring-flavoprotein dehydrogenase	0.172
ECI2	enoyl-CoA delta isomerase 2	0.154
ADH1A	alcohol dehydrogenase 1A (class I), alpha polypeptide	0.133	Human Rat
ZHX1	zinc fingers and homeoboxes 1	0.128
CAT	catalase	0.110
AADAC	arylacetamide deacetylase (esterase)	0.105
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.105
C6	complement component 6	0.093
RNASE4	ribonuclease, RNase A family, 4	0.092
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.088
AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)	0.087	Human
PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)	0.083
IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	0.068
FAM82B	family with sequence similarity 82, member B	0.056
AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	0.053
NQO1	NAD(P)H dehydrogenase, quinone 1	0.052
C9	complement component 9	0.048
C4BPB	complement component 4 binding protein, beta	0.048
C2orf18	chromosome 2 open reading frame 18	0.046
CRYZ	crystallin, zeta (quinone reductase)	0.045
ADH6	alcohol dehydrogenase 6 (class V)	0.045
CYB5A	cytochrome b5 type A (microsomal)	0.044
PRDX6	peroxiredoxin 6	0.044
PIR	pirin (iron-binding nuclear protein)	0.042
UGT1A3	UDP glucuronosyltransferase 1 family, polypeptide A3	0.040
NUPR1	nuclear protein, transcriptional regulator, 1	0.040
F11	coagulation factor XI	0.039
ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	0.036
MAOA	monoamine oxidase A	0.036
HSD17B4	hydroxysteroid (17-beta) dehydrogenase 4	0.036
SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3	0.036
ANGPTL3	angiopoietin-like 3	0.035
HRSP12	heat-responsive protein 12	0.035
ALDH1A1	aldehyde dehydrogenase 1 family, member A1	0.034	Yeast Mouse
OTC	ornithine carbamoyltransferase	0.032
F9	coagulation factor IX	0.031
C10orf116	chromosome 10 open reading frame 116	0.030
HADHA	hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit	0.027
CYP4A11	cytochrome P450, family 4, subfamily A, polypeptide 11	0.027
ALDOB	aldolase B, fructose-bisphosphate	0.026
CRP	C-reactive protein, pentraxin-related	0.026
FABP1	fatty acid binding protein 1, liver	0.026
KNG1	kininogen 1	0.026
CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	0.025
AFM	afamin	0.025
APCS	amyloid P component, serum	0.024
ASPA	aspartoacylase	0.024
CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6	0.024
ALDH3A2	aldehyde dehydrogenase 3 family, member A2	0.024
HABP2	hyaluronan binding protein 2	0.023
PLG	plasminogen	0.022
FMO3	flavin containing monooxygenase 3	0.022
HMGCS2	3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)	0.022
GSTA3	glutathione S-transferase alpha 3	0.021
EPHX1	epoxide hydrolase 1, microsomal (xenobiotic)	0.021
BHMT	betaine--homocysteine S-methyltransferase	0.021
HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2	0.021
ACAA2	acetyl-CoA acyltransferase 2	0.021
ABCA8	ATP-binding cassette, sub-family A (ABC1), member 8	0.020
MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)	0.020
C8A	complement component 8, alpha polypeptide	0.020
DIO1	deiodinase, iodothyronine, type I	0.020
FABP2	fatty acid binding protein 2, intestinal	0.020
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.019
FGB	fibrinogen beta chain	0.019
LECT2	leukocyte cell-derived chemotaxin 2	0.019
NUDT6	nudix (nucleoside diphosphate linked moiety X)-type motif 6	0.018
AOX1	aldehyde oxidase 1	0.018
RPAIN	RPA interacting protein	0.018
DAD1	defender against cell death 1	0.018
SLC17A4	solute carrier family 17 (sodium phosphate), member 4	0.018
GPX2	glutathione peroxidase 2 (gastrointestinal)	0.018
ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2	0.018
TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)	0.018
GPX3	glutathione peroxidase 3 (plasma)	0.018
CES1	carboxylesterase 1	0.018
GLYAT	glycine-N-acyltransferase	0.017
ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6	0.017
G6PC	glucose-6-phosphatase, catalytic subunit	0.017
UGT1A1	UDP glucuronosyltransferase 1 family, polypeptide A1	0.017
CYHR1	cysteine/histidine-rich 1	0.017
TAT	tyrosine aminotransferase	0.017
ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	0.017
NDUFB5	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa	0.017
CYP4F11	cytochrome P450, family 4, subfamily F, polypeptide 11	0.017
SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1	0.016
CPT2	carnitine palmitoyltransferase 2	0.016
CD302	CD302 molecule	0.016
DPYS	dihydropyrimidinase	0.016
MAT1A	methionine adenosyltransferase I, alpha	0.016
DEFB1	defensin, beta 1	0.016
SLC17A1	solute carrier family 17 (sodium phosphate), member 1	0.016
ACO1	aconitase 1, soluble	0.016
ALDH9A1	aldehyde dehydrogenase 9 family, member A1	0.016
CFH	complement factor H	0.016
UPK1B	uroplakin 1B	0.015
ARG1	arginase, liver	0.015
SEPP1	selenoprotein P, plasma, 1	0.015
CLCA2	chloride channel accessory 2	0.015
LDHB	lactate dehydrogenase B	0.015
SERPINA5	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5	0.014
SULT1E1	sulfotransferase family 1E, estrogen-preferring, member 1	0.014
CYP4F12	cytochrome P450, family 4, subfamily F, polypeptide 12	0.014
ANXA4	annexin A4	0.014
FIGF	c-fos induced growth factor (vascular endothelial growth factor D)	0.014
SELENBP1	selenium binding protein 1	0.014
HDDC2	HD domain containing 2	0.014
HAL	histidine ammonia-lyase	0.014
CYP3A7	cytochrome P450, family 3, subfamily A, polypeptide 7	0.014
SLC22A1	solute carrier family 22 (organic cation transporter), member 1	0.014
PRDX4	peroxiredoxin 4	0.014
SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2	0.014
DYNLL1	dynein, light chain, LC8-type 1	0.014
ACE2	angiotensin I converting enzyme (peptidyl-dipeptidase A) 2	0.014
FABP4	fatty acid binding protein 4, adipocyte	0.014
FGL1	fibrinogen-like 1	0.013
NR1I2	nuclear receptor subfamily 1, group I, member 2	0.013
CYP4F2	cytochrome P450, family 4, subfamily F, polypeptide 2	0.013
ANXA10	annexin A10	0.013
MAOB	monoamine oxidase B	0.013
NDUFAF1	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1	0.013
SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1	0.013
HSDL2	hydroxysteroid dehydrogenase like 2	0.013
TM4SF5	transmembrane 4 L six family member 5	0.013
GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type	0.013
ANXA13	annexin A13	0.013
ALDH7A1	aldehyde dehydrogenase 7 family, member A1	0.013
PIGC	phosphatidylinositol glycan anchor biosynthesis, class C	0.013
C15orf63	chromosome 15 open reading frame 63	0.013
ACOX1	acyl-CoA oxidase 1, palmitoyl	0.013
PON1	paraoxonase 1	0.012
C1orf123	chromosome 1 open reading frame 123	0.012
LGALS4	lectin, galactoside-binding, soluble, 4	0.012
C7	complement component 7	0.012
AHSG	alpha-2-HS-glycoprotein	0.012
CETN2	centrin, EF-hand protein, 2	0.012
APOF	apolipoprotein F	0.012
BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)	0.012
MGST1	microsomal glutathione S-transferase 1	0.012
FMO4	flavin containing monooxygenase 4	0.012
DHRS3	dehydrogenase/reductase (SDR family) member 3	0.012	Human
ACADL	acyl-CoA dehydrogenase, long chain	0.012
ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	0.012	Yeast
ABCG2	ATP-binding cassette, sub-family G (WHITE), member 2	0.012
ADIPOQ	adiponectin, C1Q and collagen domain containing	0.012
CYP4F3	cytochrome P450, family 4, subfamily F, polypeptide 3	0.012
HGD	homogentisate 1,2-dioxygenase	0.011
ASS1	argininosuccinate synthase 1	0.011
NR1H4	nuclear receptor subfamily 1, group H, member 4	0.011
IGF1	insulin-like growth factor 1 (somatomedin C)	0.011
CDO1	cysteine dioxygenase, type I	0.011
FMO2	flavin containing monooxygenase 2 (non-functional)	0.011
ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12	0.011
EHHADH	enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase	0.011
HPD	4-hydroxyphenylpyruvate dioxygenase	0.011
EPHX2	epoxide hydrolase 2, cytoplasmic	0.011
AZGP1	alpha-2-glycoprotein 1, zinc-binding	0.011
HRG	histidine-rich glycoprotein	0.011
UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4	0.011
SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7	0.011
HNMT	histamine N-methyltransferase	0.011
ALDH1L1	aldehyde dehydrogenase 1 family, member L1	0.011
TM4SF4	transmembrane 4 L six family member 4	0.011
AFP	alpha-fetoprotein	0.011
ECM2	extracellular matrix protein 2, female organ and adipocyte specific	0.011
TSPAN8	tetraspanin 8	0.011
RARRES1	retinoic acid receptor responder (tazarotene induced) 1	0.011
ALDH3A1	aldehyde dehydrogenase 3 family, member A1	0.011	Human
GBA3	glucosidase, beta, acid 3 (cytosolic)	0.011
RPS27L	ribosomal protein S27-like	0.010
USP50	ubiquitin specific peptidase 50	0.010
GYS2	glycogen synthase 2 (liver)	0.010
CCL16	chemokine (C-C motif) ligand 16	0.010
CYP3A43	cytochrome P450, family 3, subfamily A, polypeptide 43	0.010
RBBP7	retinoblastoma binding protein 7	0.010
LIPC	lipase, hepatic	0.010
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.010
CYP2C8	cytochrome P450, family 2, subfamily C, polypeptide 8	0.010
SLURP1	secreted LY6/PLAUR domain containing 1	0.010
MTTP	microsomal triglyceride transfer protein	0.010
ME1	malic enzyme 1, NADP(+)-dependent, cytosolic	0.010