IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna

Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna "

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna " (in gray)

Name	Description	Probability	Func Analog Organism
BOP1	block of proliferation 1	0.786
NOP56	NOP56 ribonucleoprotein homolog (yeast)	0.694
NOP2	NOP2 nucleolar protein homolog (yeast)	0.655	Yeast
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	0.599
PES1	pescadillo homolog 1, containing BRCT domain (zebrafish)	0.569
MYBBP1A	MYB binding protein (P160) 1a	0.514
NOLC1	nucleolar and coiled-body phosphoprotein 1	0.484
NOP58	NOP58 ribonucleoprotein homolog (yeast)	0.321
POLR1C	polymerase (RNA) I polypeptide C, 30kDa	0.311
C10orf2	chromosome 10 open reading frame 2	0.233
LYAR	Ly1 antibody reactive homolog (mouse)	0.227
PUS1	pseudouridylate synthase 1	0.144
GNL2	guanine nucleotide binding protein-like 2 (nucleolar)	0.104
NOL11	nucleolar protein 11	0.102
DKC1	dyskeratosis congenita 1, dyskerin	0.088
MKI67IP	MKI67 (FHA domain) interacting nucleolar phosphoprotein	0.081
PPRC1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.059
TRMT1	TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)	0.054
FTSJ3	FtsJ homolog 3 (E. coli)	0.053
PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.049
RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	0.048
IPO4	importin 4	0.047
UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	0.046
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	0.046
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.045
WDR74	WD repeat domain 74	0.040
NOP14	NOP14 nucleolar protein homolog (yeast)	0.040
WDR3	WD repeat domain 3	0.037
DPH2	DPH2 homolog (S. cerevisiae)	0.036
MRTO4	mRNA turnover 4 homolog (S. cerevisiae)	0.036
DHX37	DEAH (Asp-Glu-Ala-His) box polypeptide 37	0.035
NOB1	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)	0.034
PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	0.032
RRP9	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	0.031
URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	0.031
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.029
SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein	0.027
ZC3H15	zinc finger CCCH-type containing 15	0.026
RSL24D1	ribosomal L24 domain containing 1	0.025
KIAA0020	KIAA0020	0.024
PTRH2	peptidyl-tRNA hydrolase 2	0.024
ATAD3A	ATPase family, AAA domain containing 3A	0.024
NDUFAF2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2	0.022
NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	0.022
ABCF2	ATP-binding cassette, sub-family F (GCN20), member 2	0.022
RPL36AL	ribosomal protein L36a-like	0.022
BTF3	basic transcription factor 3	0.021
RBM17	RNA binding motif protein 17	0.021
RRP12	ribosomal RNA processing 12 homolog (S. cerevisiae)	0.020
PDCD11	programmed cell death 11	0.020	Yeast
MPHOSPH10	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)	0.020
WDR46	WD repeat domain 46	0.020
RPL29	ribosomal protein L29	0.020
TTC27	tetratricopeptide repeat domain 27	0.020
BMS1	BMS1 homolog, ribosome assembly protein (yeast)	0.020
DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	0.019
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.019
NSUN2	NOP2/Sun domain family, member 2	0.019
RIOK1	RIO kinase 1 (yeast)	0.019
CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	0.019
WDR43	WD repeat domain 43	0.018
SNRPB2	small nuclear ribonucleoprotein polypeptide B	0.018
IPO7	importin 7	0.018
PWP2	PWP2 periodic tryptophan protein homolog (yeast)	0.018
HEATR1	HEAT repeat containing 1	0.018
NOL8	nucleolar protein 8	0.017
GRWD1	glutamate-rich WD repeat containing 1	0.017
NOL6	nucleolar protein family 6 (RNA-associated)	0.017
CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)	0.017
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.017
MAK16	MAK16 homolog (S. cerevisiae)	0.017
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.016
RBM28	RNA binding motif protein 28	0.016	Yeast
EEF1B2	eukaryotic translation elongation factor 1 beta 2	0.016
SELRC1	Sel1 repeat containing 1	0.015
ZNF259	zinc finger protein 259	0.015
NAT10	N-acetyltransferase 10 (GCN5-related)	0.015
WDR75	WD repeat domain 75	0.015
RPL17	ribosomal protein L17	0.014
BYSL	bystin-like	0.014
RPS10	ribosomal protein S10	0.014
METTL1	methyltransferase like 1	0.014
WDR12	WD repeat domain 12	0.014
NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)	0.014
EIF1AX	eukaryotic translation initiation factor 1A, X-linked	0.014
MRPS5	mitochondrial ribosomal protein S5	0.014
PWP1	PWP1 homolog (S. cerevisiae)	0.014
C14orf166	chromosome 14 open reading frame 166	0.014
FKBP4	FK506 binding protein 4, 59kDa	0.014
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.014
RPL35A	ribosomal protein L35a	0.013
PPAN	peter pan homolog (Drosophila)	0.013	Yeast
KIAA0664	KIAA0664	0.013
NCL	nucleolin	0.013
UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	0.013
ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.013
POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	0.013
PMM2	phosphomannomutase 2	0.012
TRMU	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	0.012
NACA	nascent polypeptide-associated complex alpha subunit	0.012
RPL38	ribosomal protein L38	0.012
EIF2A	eukaryotic translation initiation factor 2A, 65kDa	0.012
SLC5A6	solute carrier family 5 (sodium-dependent vitamin transporter), member 6	0.012
TSTA3	tissue specific transplantation antigen P35B	0.012
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.012
CCDC86	coiled-coil domain containing 86	0.012
TCOF1	Treacher Collins-Franceschetti syndrome 1	0.012
RPP40	ribonuclease P/MRP 40kDa subunit	0.012
DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	0.012
RPF2	ribosome production factor 2 homolog (S. cerevisiae)	0.012	Yeast
RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	0.011
NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	0.011
PRPF4	PRP4 pre-mRNA processing factor 4 homolog (yeast)	0.011
UBIAD1	UbiA prenyltransferase domain containing 1	0.011
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.011
DDX31	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31	0.011	Yeast
RPL36	ribosomal protein L36	0.011
NLE1	notchless homolog 1 (Drosophila)	0.011
PRPF3	PRP3 pre-mRNA processing factor 3 homolog (S. cerevisiae)	0.011
UCK2	uridine-cytidine kinase 2	0.011
NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	0.010
METAP2	methionyl aminopeptidase 2	0.010
UTP3	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	0.010
RCC1	regulator of chromosome condensation 1	0.010
FBL	fibrillarin	0.010
POLR1E	polymerase (RNA) I polypeptide E, 53kDa	0.010