IMP: Integrative Multi-species Prediction

Homo sapiens

2 genes annotated in human

maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna

Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna "

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna " (in gray)

Name	Description	Probability	Func Analog Organism
EXOSC3	exosome component 3	0.999	Yeast
EXOSC7	exosome component 7	0.995	Yeast
EXOSC4	exosome component 4	0.995	Yeast
EXOSC2	exosome component 2	0.990	Yeast
EXOSC10	exosome component 10	0.963	Yeast
BOP1	block of proliferation 1	0.885	Mouse
NOLC1	nucleolar and coiled-body phosphoprotein 1	0.856
DIS3L	DIS3 mitotic control homolog (S. cerevisiae)-like	0.846
GNL3	guanine nucleotide binding protein-like 3 (nucleolar)	0.795
WDR3	WD repeat domain 3	0.795	Yeast
NOP56	NOP56 ribonucleoprotein homolog (yeast)	0.785
MYBBP1A	MYB binding protein (P160) 1a	0.687
PPAN	peter pan homolog (Drosophila)	0.632
DDX21	DEAD (Asp-Glu-Ala-Asp) box polypeptide 21	0.626
PES1	pescadillo homolog 1, containing BRCT domain (zebrafish)	0.623
EXOSC1	exosome component 1	0.576	Yeast
NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	0.554
PUS1	pseudouridylate synthase 1	0.468
C10orf2	chromosome 10 open reading frame 2	0.385
WDR74	WD repeat domain 74	0.368
EXOSC9	exosome component 9	0.367	Yeast
RPP40	ribonuclease P/MRP 40kDa subunit	0.359
FTSJ3	FtsJ homolog 3 (E. coli)	0.334
FBL	fibrillarin	0.333
EXOSC5	exosome component 5	0.288	Yeast
TGS1	trimethylguanosine synthase 1	0.272
CEBPZ	CCAAT/enhancer binding protein (C/EBP), zeta	0.271
TRMT1	TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)	0.261
NOP2	NOP2 nucleolar protein homolog (yeast)	0.256
MAK16	MAK16 homolog (S. cerevisiae)	0.253
NOL11	nucleolar protein 11	0.242
DIS3	DIS3 mitotic control homolog (S. cerevisiae)	0.240
WDR43	WD repeat domain 43	0.233
RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	0.202
IPO4	importin 4	0.198
RRP9	ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)	0.180
DIMT1L	DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)	0.176
DKC1	dyskeratosis congenita 1, dyskerin	0.170
EIF3H	eukaryotic translation initiation factor 3, subunit H	0.164
MKI67IP	MKI67 (FHA domain) interacting nucleolar phosphoprotein	0.163
NUFIP1	nuclear fragile X mental retardation protein interacting protein 1	0.162
KIAA0020	KIAA0020	0.158
EIF5B	eukaryotic translation initiation factor 5B	0.152
POLR1C	polymerase (RNA) I polypeptide C, 30kDa	0.149
CCDC86	coiled-coil domain containing 86	0.148
TSR1	TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)	0.146
PDCD11	programmed cell death 11	0.139	Yeast
DPH2	DPH2 homolog (S. cerevisiae)	0.136
EXOSC8	exosome component 8	0.127
WDR75	WD repeat domain 75	0.124
MPHOSPH6	M-phase phosphoprotein 6	0.119
PTRH2	peptidyl-tRNA hydrolase 2	0.116
HEATR1	HEAT repeat containing 1	0.113	Yeast
DDX47	DEAD (Asp-Glu-Ala-Asp) box polypeptide 47	0.108
ZNF593	zinc finger protein 593	0.101
DNTTIP2	deoxynucleotidyltransferase, terminal, interacting protein 2	0.100
LYAR	Ly1 antibody reactive homolog (mouse)	0.093
EIF3E	eukaryotic translation initiation factor 3, subunit E	0.091
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.084
USP4	ubiquitin specific peptidase 4 (proto-oncogene)	0.082
BYSL	bystin-like	0.082	Yeast
NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)	0.081
UTP14A	UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)	0.075
G3BP1	GTPase activating protein (SH3 domain) binding protein 1	0.074
ATAD3A	ATPase family, AAA domain containing 3A	0.070
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.069
BMS1	BMS1 homolog, ribosome assembly protein (yeast)	0.067
NOP14	NOP14 nucleolar protein homolog (yeast)	0.066	Yeast
EBNA1BP2	EBNA1 binding protein 2	0.066
NOC3L	nucleolar complex associated 3 homolog (S. cerevisiae)	0.065
PA2G4	proliferation-associated 2G4, 38kDa	0.064
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.063
KIAA0664	KIAA0664	0.060
UTP3	UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)	0.059
CCT4	chaperonin containing TCP1, subunit 4 (delta)	0.057
WDR12	WD repeat domain 12	0.056
PPAT	phosphoribosyl pyrophosphate amidotransferase	0.056
POLR1E	polymerase (RNA) I polypeptide E, 53kDa	0.055
BRIX1	BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)	0.052
TBL3	transducin (beta)-like 3	0.052	Yeast
MRTO4	mRNA turnover 4 homolog (S. cerevisiae)	0.050
RPF2	ribosome production factor 2 homolog (S. cerevisiae)	0.049	Yeast
NLE1	notchless homolog 1 (Drosophila)	0.049
CIRH1A	cirrhosis, autosomal recessive 1A (cirhin)	0.048
NDUFAF2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2	0.048
TTC27	tetratricopeptide repeat domain 27	0.047
EEF1B2	eukaryotic translation elongation factor 1 beta 2	0.047
RIOK1	RIO kinase 1 (yeast)	0.047
RRP15	ribosomal RNA processing 15 homolog (S. cerevisiae)	0.047
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.046
BTF3	basic transcription factor 3	0.045
EIF3B	eukaryotic translation initiation factor 3, subunit B	0.045
GNL2	guanine nucleotide binding protein-like 2 (nucleolar)	0.045
TFAM	transcription factor A, mitochondrial	0.044
SUGP1	SURP and G patch domain containing 1	0.043
EIF3M	eukaryotic translation initiation factor 3, subunit M	0.043
SLC19A1	solute carrier family 19 (folate transporter), member 1	0.042
ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	0.042
EIF3D	eukaryotic translation initiation factor 3, subunit D	0.042
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.042
PNO1	partner of NOB1 homolog (S. cerevisiae)	0.042	Yeast
RRP7A	ribosomal RNA processing 7 homolog A (S. cerevisiae)	0.041
DDX27	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	0.040
SSB	Sjogren syndrome antigen B (autoantigen La)	0.040
NOC2L	nucleolar complex associated 2 homolog (S. cerevisiae)	0.040
URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	0.038
EED	embryonic ectoderm development	0.036
BCCIP	BRCA2 and CDKN1A interacting protein	0.036
PUS7	pseudouridylate synthase 7 homolog (S. cerevisiae)	0.035
RBM17	RNA binding motif protein 17	0.035
TOMM40	translocase of outer mitochondrial membrane 40 homolog (yeast)	0.034
NME1-NME2	NME1-NME2 readthrough	0.034
CLNS1A	chloride channel, nucleotide-sensitive, 1A	0.034
PUS3	pseudouridylate synthase 3	0.034
IMPDH2	IMP (inosine 5'-monophosphate) dehydrogenase 2	0.032
NOSIP	nitric oxide synthase interacting protein	0.031
NOB1	NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)	0.031
GRWD1	glutamate-rich WD repeat containing 1	0.031
DHX37	DEAH (Asp-Glu-Ala-His) box polypeptide 37	0.030
ZNF259	zinc finger protein 259	0.030
SELRC1	Sel1 repeat containing 1	0.029
ATAD3B	ATPase family, AAA domain containing 3B	0.029
TELO2	TEL2, telomere maintenance 2, homolog (S. cerevisiae)	0.029
NAT10	N-acetyltransferase 10 (GCN5-related)	0.028
CDK9	cyclin-dependent kinase 9	0.028
CWC27	CWC27 spliceosome-associated protein homolog (S. cerevisiae)	0.027
HSPA14	heat shock 70kDa protein 14	0.027
PPA1	pyrophosphatase (inorganic) 1	0.027
DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18	0.027
BZW2	basic leucine zipper and W2 domains 2	0.027
UCK2	uridine-cytidine kinase 2	0.027
PPRC1	peroxisome proliferator-activated receptor gamma, coactivator-related 1	0.026
TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	0.026
ECSIT	ECSIT homolog (Drosophila)	0.025
DDX10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10	0.024
PAK1IP1	PAK1 interacting protein 1	0.024	Yeast
RG9MTD1	RNA (guanine-9-) methyltransferase domain containing 1	0.024
SURF6	surfeit 6	0.023
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.023
RBM28	RNA binding motif protein 28	0.023
C12orf45	chromosome 12 open reading frame 45	0.022
TMEM161A	transmembrane protein 161A	0.022
RARS	arginyl-tRNA synthetase	0.022
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.022
HDAC3	histone deacetylase 3	0.022
SGTA	small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha	0.021
C3orf26	chromosome 3 open reading frame 26	0.021
EEF1E1	eukaryotic translation elongation factor 1 epsilon 1	0.021
CCDC94	coiled-coil domain containing 94	0.021
UTP15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)	0.021
SYVN1	synovial apoptosis inhibitor 1, synoviolin	0.021
CCNH	cyclin H	0.020
GAR1	GAR1 ribonucleoprotein homolog (yeast)	0.020
LTV1	LTV1 homolog (S. cerevisiae)	0.020
USP36	ubiquitin specific peptidase 36	0.020
NKRF	NFKB repressing factor	0.020
NPM3	nucleophosmin/nucleoplasmin 3	0.019
EIF3G	eukaryotic translation initiation factor 3, subunit G	0.019
TSSC4	tumor suppressing subtransferable candidate 4	0.019
NOP16	NOP16 nucleolar protein homolog (yeast)	0.019
PWP2	PWP2 periodic tryptophan protein homolog (yeast)	0.018
DNAJC2	DnaJ (Hsp40) homolog, subfamily C, member 2	0.018
IPO5	importin 5	0.018
METTL1	methyltransferase like 1	0.018
BIN1	bridging integrator 1	0.018
NHP2	NHP2 ribonucleoprotein homolog (yeast)	0.018
ARMC6	armadillo repeat containing 6	0.017
PELP1	proline, glutamate and leucine rich protein 1	0.017
RNF126	ring finger protein 126	0.017
RSL1D1	ribosomal L1 domain containing 1	0.017
VARS	valyl-tRNA synthetase	0.017
TRMU	tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase	0.017
UBIAD1	UbiA prenyltransferase domain containing 1	0.017
DDX54	DEAD (Asp-Glu-Ala-Asp) box polypeptide 54	0.017	Yeast
SUPV3L1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.017
SURF2	surfeit 2	0.017
GAPDH	glyceraldehyde-3-phosphate dehydrogenase	0.016
C19orf24	chromosome 19 open reading frame 24	0.016
IMP4	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)	0.016
RBM10	RNA binding motif protein 10	0.016
NARS2	asparaginyl-tRNA synthetase 2, mitochondrial (putative)	0.016
RPS21	ribosomal protein S21	0.016
UTP18	UTP18, small subunit (SSU) processome component, homolog (yeast)	0.016	Yeast
MAX	MYC associated factor X	0.015
POLR3G	polymerase (RNA) III (DNA directed) polypeptide G (32kD)	0.015
SRSF7	serine/arginine-rich splicing factor 7	0.015
WDR46	WD repeat domain 46	0.015
GCN1L1	GCN1 general control of amino-acid synthesis 1-like 1 (yeast)	0.015
RPL36AL	ribosomal protein L36a-like	0.015
ZC3H15	zinc finger CCCH-type containing 15	0.015
DDX31	DEAD (Asp-Glu-Ala-Asp) box polypeptide 31	0.015
PWP1	PWP1 homolog (S. cerevisiae)	0.015
RPIA	ribose 5-phosphate isomerase A	0.015
DIEXF	digestive organ expansion factor homolog (zebrafish)	0.015
AXIN1	axin 1	0.015
PINX1	PIN2/TERF1 interacting, telomerase inhibitor 1	0.014
UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	0.014
UCHL3	ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)	0.014
PRPF19	PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)	0.014
MPHOSPH10	M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)	0.014	Yeast
NOL8	nucleolar protein 8	0.013
REXO4	REX4, RNA exonuclease 4 homolog (S. cerevisiae)	0.013
PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)	0.013
C12orf24	chromosome 12 open reading frame 24	0.013
RRP1	ribosomal RNA processing 1 homolog (S. cerevisiae)	0.013
PITPNB	phosphatidylinositol transfer protein, beta	0.013
UTP6	UTP6, small subunit (SSU) processome component, homolog (yeast)	0.013
BAK1	BCL2-antagonist/killer 1	0.013
SHQ1	SHQ1 homolog (S. cerevisiae)	0.013
SMYD5	SMYD family member 5	0.013
WDR4	WD repeat domain 4	0.013
ECD	ecdysoneless homolog (Drosophila)	0.013
TRAP1	TNF receptor-associated protein 1	0.013
CDK5RAP1	CDK5 regulatory subunit associated protein 1	0.013
AUP1	ancient ubiquitous protein 1	0.013
YARS2	tyrosyl-tRNA synthetase 2, mitochondrial	0.013
RRP1B	ribosomal RNA processing 1 homolog B (S. cerevisiae)	0.013
TRMT6	tRNA methyltransferase 6 homolog (S. cerevisiae)	0.013
EIF3CL	eukaryotic translation initiation factor 3, subunit C-like	0.013
LDHB	lactate dehydrogenase B	0.013
TRIAP1	TP53 regulated inhibitor of apoptosis 1	0.012
GADD45GIP1	growth arrest and DNA-damage-inducible, gamma interacting protein 1	0.012
SCRIB	scribbled homolog (Drosophila)	0.012
EXOSC6	exosome component 6	0.012
MPP6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)	0.012
ODC1	ornithine decarboxylase 1	0.012
THOP1	thimet oligopeptidase 1	0.012
EIF2S2	eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa	0.012
RBM15	RNA binding motif protein 15	0.012
EIF4A1	eukaryotic translation initiation factor 4A1	0.012
SART1	squamous cell carcinoma antigen recognized by T cells	0.012
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.011
RBMX	RNA binding motif protein, X-linked	0.011
DDX24	DEAD (Asp-Glu-Ala-Asp) box polypeptide 24	0.011	Yeast
C14orf166	chromosome 14 open reading frame 166	0.011
RAE1	RAE1 RNA export 1 homolog (S. pombe)	0.011
ESF1	ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)	0.011
RIOK2	RIO kinase 2 (yeast)	0.011
SPATA5L1	spermatogenesis associated 5-like 1	0.011
GTPBP6	GTP binding protein 6 (putative)	0.011
C2orf3	chromosome 2 open reading frame 3	0.011
URM1	ubiquitin related modifier 1	0.011
TRDMT1	tRNA aspartic acid methyltransferase 1	0.011
KPNB1	karyopherin (importin) beta 1	0.011
RCL1	RNA terminal phosphate cyclase-like 1	0.011
FARSA	phenylalanyl-tRNA synthetase, alpha subunit	0.010
FBXW8	F-box and WD repeat domain containing 8	0.010
TRMT61A	tRNA methyltransferase 61 homolog A (S. cerevisiae)	0.010
HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1	0.010
ZBTB17	zinc finger and BTB domain containing 17	0.010
IRAK1	interleukin-1 receptor-associated kinase 1	0.010
RPS26	ribosomal protein S26	0.010