IMP: Integrative Multi-species Prediction

Homo sapiens

25 genes annotated in human

Multi-species View

protein localization to mitochondrion

GO:0070585

A process in which a protein is transported to, or maintained in, a location within the mitochondrion.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein localization to mitochondrion"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "protein localization to mitochondrion" (in gray)

Name	Description	Probability	Func Analog Organism
PPID	peptidylprolyl isomerase D	0.970
MARCH5	membrane-associated ring finger (C3HC4) 5	0.922
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.863
TIMM10	translocase of inner mitochondrial membrane 10 homolog (yeast)	0.819
HSPA1B	heat shock 70kDa protein 1B	0.789	Yeast
HSPA1A	heat shock 70kDa protein 1A	0.769	Yeast
HSPA8	heat shock 70kDa protein 8	0.754	Yeast
PINK1	PTEN induced putative kinase 1	0.634
BAK1	BCL2-antagonist/killer 1	0.627
TIMM8B	translocase of inner mitochondrial membrane 8 homolog B (yeast)	0.530	Yeast
TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)	0.485	Yeast
TOMM22	translocase of outer mitochondrial membrane 22 homolog (yeast)	0.388
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.328
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.325
SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	0.251
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.247
NUB1	negative regulator of ubiquitin-like proteins 1	0.247
TOMM70A	translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)	0.241
PAM16	presequence translocase-associated motor 16 homolog (S. cerevisiae)	0.220	Yeast
TIMM23	translocase of inner mitochondrial membrane 23 homolog (yeast) and translocase of inner mitochondrial membrane 23 homolog (yeast)	0.161	Yeast
TCP1	t-complex 1	0.156
MFN2	mitofusin 2	0.152
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.144
MAPK8	mitogen-activated protein kinase 8	0.142
CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1	0.137
BECN1	beclin 1, autophagy related	0.136
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.133
MRPL24	mitochondrial ribosomal protein L24	0.129
ST13	suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)	0.126
ATP5G1	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)	0.105
DNM1L	dynamin 1-like	0.097	Mouse
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.087	Human
SMCR7	Smith-Magenis syndrome chromosome region, candidate 7	0.084
PGK1	phosphoglycerate kinase 1	0.077
IDH3A	isocitrate dehydrogenase 3 (NAD+) alpha	0.075
EIF5	eukaryotic translation initiation factor 5	0.074
HCCS	holocytochrome c synthase	0.073
PPP5C	protein phosphatase 5, catalytic subunit	0.065
NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa	0.065
ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)	0.062
HSPH1	heat shock 105kDa/110kDa protein 1	0.062	Human
AZIN1	antizyme inhibitor 1	0.062
ZNF746	zinc finger protein 746	0.061
XPO7	exportin 7	0.059
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.057
MRPL35	mitochondrial ribosomal protein L35	0.055
MAP2K4	mitogen-activated protein kinase kinase 4	0.054
HUWE1	HECT, UBA and WWE domain containing 1	0.053
BAG3	BCL2-associated athanogene 3	0.053
SKA3	spindle and kinetochore associated complex subunit 3	0.052
DNAJC19	DnaJ (Hsp40) homolog, subfamily C, member 19	0.048	Yeast
NDUFAF4	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4	0.048
TOMM20	translocase of outer mitochondrial membrane 20 homolog (yeast)	0.047
AIFM1	apoptosis-inducing factor, mitochondrion-associated, 1	0.047
MRPS7	mitochondrial ribosomal protein S7	0.046
TOMM7	translocase of outer mitochondrial membrane 7 homolog (yeast)	0.046
BAG2	BCL2-associated athanogene 2	0.045
BAX	BCL2-associated X protein	0.044	Mouse
CYCS	cytochrome c, somatic	0.041
GCDH	glutaryl-CoA dehydrogenase	0.041
BCL2L1	BCL2-like 1	0.041
SKA1	spindle and kinetochore associated complex subunit 1	0.041
ARMC6	armadillo repeat containing 6	0.040
DLAT	dihydrolipoamide S-acetyltransferase	0.040
AHSA1	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)	0.040
PMVK	phosphomevalonate kinase	0.038
COX6B1	cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)	0.038
RNF144B	ring finger protein 144B	0.038
TP53BP2	tumor protein p53 binding protein, 2	0.038
GLRX3	glutaredoxin 3	0.037
TIMM9	translocase of inner mitochondrial membrane 9 homolog (yeast)	0.037
MEOX2	mesenchyme homeobox 2	0.035
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.035
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.034
TXN2	thioredoxin 2	0.033
C19orf70	chromosome 19 open reading frame 70	0.033
HSPE1	heat shock 10kDa protein 1 (chaperonin 10)	0.032
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.031
BIK	BCL2-interacting killer (apoptosis-inducing)	0.030
VDAC1	voltage-dependent anion channel 1	0.030
SERTAD4	SERTA domain containing 4	0.030
UQCR10	ubiquinol-cytochrome c reductase, complex III subunit X	0.029
BCL2	B-cell CLL/lymphoma 2	0.028
STIP1	stress-induced-phosphoprotein 1	0.028
ATP6V1C1	ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1	0.028
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.028	Yeast
NARS	asparaginyl-tRNA synthetase	0.027
HSPA4	heat shock 70kDa protein 4	0.027
SLC25A46	solute carrier family 25, member 46	0.026
GRSF1	G-rich RNA sequence binding factor 1	0.026
NDUFS3	NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)	0.026
NMD3	NMD3 homolog (S. cerevisiae)	0.026
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.026
TIMM17A	translocase of inner mitochondrial membrane 17 homolog A (yeast)	0.025	Yeast
HSD17B10	hydroxysteroid (17-beta) dehydrogenase 10	0.025
MAGEH1	melanoma antigen family H, 1	0.025
GFM1	G elongation factor, mitochondrial 1	0.025
CHCHD4	coiled-coil-helix-coiled-coil-helix domain containing 4	0.025
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.024
TBK1	TANK-binding kinase 1	0.023
EI24	etoposide induced 2.4 mRNA	0.023
BOLA3	bolA homolog 3 (E. coli)	0.022
IDH3B	isocitrate dehydrogenase 3 (NAD+) beta	0.022
DDT	D-dopachrome tautomerase	0.022
CIAPIN1	cytokine induced apoptosis inhibitor 1	0.022
BAD	BCL2-associated agonist of cell death	0.021
CHCHD8	coiled-coil-helix-coiled-coil-helix domain containing 8	0.021
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.021	Mouse
KIAA0664	KIAA0664	0.021
TRIP12	thyroid hormone receptor interactor 12	0.021
ETF1	eukaryotic translation termination factor 1	0.020
NAA10	N(alpha)-acetyltransferase 10, NatA catalytic subunit	0.020
RABGGTB	Rab geranylgeranyltransferase, beta subunit	0.020
BCL2A1	BCL2-related protein A1	0.019
GTPBP4	GTP binding protein 4	0.019
NDUFAB1	NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa	0.019
AMBRA1	autophagy/beclin-1 regulator 1	0.018
RPP14	ribonuclease P/MRP 14kDa subunit	0.018
TUSC2	tumor suppressor candidate 2	0.018
MFN1	mitofusin 1	0.018	Human
TIMM44	translocase of inner mitochondrial membrane 44 homolog (yeast)	0.018
SUGT1	SGT1, suppressor of G2 allele of SKP1 (S. cerevisiae)	0.018
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.018
EIF3J	eukaryotic translation initiation factor 3, subunit J	0.017
MRPL46	mitochondrial ribosomal protein L46	0.017
DCTN3	dynactin 3 (p22)	0.017
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.017
BAG1	BCL2-associated athanogene	0.017	Mouse
MRPL11	mitochondrial ribosomal protein L11	0.017
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.017	Mouse
NDUFA11	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa	0.017
FBXO7	F-box protein 7	0.016
COQ3	coenzyme Q3 homolog, methyltransferase (S. cerevisiae)	0.016
PRDX5	peroxiredoxin 5	0.016
IARS2	isoleucyl-tRNA synthetase 2, mitochondrial	0.016
MRFAP1	Morf4 family associated protein 1	0.016
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.016
GHITM	growth hormone inducible transmembrane protein	0.016
RAB4A	RAB4A, member RAS oncogene family	0.015
GFM2	G elongation factor, mitochondrial 2	0.015
TMX2	thioredoxin-related transmembrane protein 2	0.015
XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	0.015
UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.015
CSNK1A1	casein kinase 1, alpha 1	0.015
PEX19	peroxisomal biogenesis factor 19	0.015
BBC3	BCL2 binding component 3	0.015
TUBA1A	tubulin, alpha 1a	0.015
IDE	insulin-degrading enzyme	0.014
C20orf30	chromosome 20 open reading frame 30	0.014
MRPS12	mitochondrial ribosomal protein S12	0.014
KIAA1279	KIAA1279	0.014
MRPS18A	mitochondrial ribosomal protein S18A	0.014
COX8A	cytochrome c oxidase subunit VIIIA (ubiquitous)	0.014
DLD	dihydrolipoamide dehydrogenase	0.014
BCL2L12	BCL2-like 12 (proline rich)	0.014
METTL1	methyltransferase like 1	0.014
NDUFA8	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa	0.014
EPRS	glutamyl-prolyl-tRNA synthetase	0.014
TUBB2B	tubulin, beta 2B	0.014
DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	0.014
MCAT	malonyl CoA:ACP acyltransferase (mitochondrial)	0.014
LRP6	low density lipoprotein receptor-related protein 6	0.013
C20orf7	chromosome 20 open reading frame 7	0.013
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.013
BCAP31	B-cell receptor-associated protein 31	0.013
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.013
SUPV3L1	suppressor of var1, 3-like 1 (S. cerevisiae)	0.013
NDUFA3	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa	0.013
ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7	0.013
NOP16	NOP16 nucleolar protein homolog (yeast)	0.013
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.012
ROMO1	reactive oxygen species modulator 1	0.012
TMEM126A	transmembrane protein 126A	0.012
C12orf62	chromosome 12 open reading frame 62	0.012
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.012
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.012
KPNA1	karyopherin alpha 1 (importin alpha 5)	0.012
MRPL34	mitochondrial ribosomal protein L34	0.012
MAP1B	microtubule-associated protein 1B	0.012
TMEM205	transmembrane protein 205	0.012
MECR	mitochondrial trans-2-enoyl-CoA reductase	0.012
MRPL36	mitochondrial ribosomal protein L36	0.012
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.012
RGS2	regulator of G-protein signaling 2, 24kDa	0.012
TIMM50	translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)	0.012
YAF2	YY1 associated factor 2	0.012
UQCR11	ubiquinol-cytochrome c reductase, complex III subunit XI	0.012
GLRX5	glutaredoxin 5	0.011
HSPBP1	HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1	0.011
PSMF1	proteasome (prosome, macropain) inhibitor subunit 1 (PI31)	0.011
G3BP2	GTPase activating protein (SH3 domain) binding protein 2	0.011
COMMD1	copper metabolism (Murr1) domain containing 1	0.011
FAM82A2	family with sequence similarity 82, member A2	0.011
RAB5B	RAB5B, member RAS oncogene family	0.011
TRIAP1	TP53 regulated inhibitor of apoptosis 1	0.011
PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	0.011
FEZ1	fasciculation and elongation protein zeta 1 (zygin I)	0.011
CDK7	cyclin-dependent kinase 7	0.011
UQCRQ	ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa	0.011
RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	0.010
NADSYN1	NAD synthetase 1	0.010
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.010
MKKS	McKusick-Kaufman syndrome	0.010
POLR2L	polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa	0.010
PCBD1	pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha	0.010
EXOC5	exocyst complex component 5	0.010
BID	BH3 interacting domain death agonist	0.010	Mouse
FDX1	ferredoxin 1	0.010
FAHD1	fumarylacetoacetate hydrolase domain containing 1	0.010
PEMT	phosphatidylethanolamine N-methyltransferase	0.010
PPP6C	protein phosphatase 6, catalytic subunit	0.010
USP30	ubiquitin specific peptidase 30	0.010
PNO1	partner of NOB1 homolog (S. cerevisiae)	0.010
PPP3R1	protein phosphatase 3, regulatory subunit B, alpha	0.010
FAM118B	family with sequence similarity 118, member B	0.010
SIRT3	sirtuin 3	0.010