IMP: Integrative Multi-species Prediction

Homo sapiens

3 genes annotated in human

neural tube closure

The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "neural tube closure"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "neural tube closure" (in gray)

Name	Description	Probability	Func Analog Organism
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.603
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.601	Mouse
TSC2	tuberous sclerosis 2	0.581	Mouse
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.570
ZFYVE9	zinc finger, FYVE domain containing 9	0.553
LRRK2	leucine-rich repeat kinase 2	0.517
BCOR	BCL6 corepressor	0.513
SASS6	spindle assembly 6 homolog (C. elegans)	0.473
AXIN1	axin 1	0.472
SMAD2	SMAD family member 2	0.460
PPP1R16A	protein phosphatase 1, regulatory (inhibitor) subunit 16A	0.426
APC	adenomatous polyposis coli	0.401
SMAD3	SMAD family member 3	0.372
ZFX	zinc finger protein, X-linked	0.342
SEC23A	Sec23 homolog A (S. cerevisiae)	0.314
DVL1	dishevelled, dsh homolog 1 (Drosophila)	0.309	Mouse
RXRA	retinoid X receptor, alpha	0.302
SETD8	SET domain containing (lysine methyltransferase) 8	0.293
TRRAP	transformation/transcription domain-associated protein	0.288
C9orf89	chromosome 9 open reading frame 89	0.279
MEOX2	mesenchyme homeobox 2	0.279
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.276
SORBS3	sorbin and SH3 domain containing 3	0.271
PCM1	pericentriolar material 1	0.242
CNKSR2	connector enhancer of kinase suppressor of Ras 2	0.230
SOX10	SRY (sex determining region Y)-box 10	0.214
MED16	mediator complex subunit 16	0.210
ABI1	abl-interactor 1	0.202
MBD2	methyl-CpG binding domain protein 2	0.183
SEC24D	SEC24 family, member D (S. cerevisiae)	0.172
DLG5	discs, large homolog 5 (Drosophila)	0.159
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.159
NCOA1	nuclear receptor coactivator 1	0.149
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.145
PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	0.143
CREBBP	CREB binding protein	0.142
WASF2	WAS protein family, member 2	0.142
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.141
GLI1	GLI family zinc finger 1	0.136
PKP4	plakophilin 4	0.132
CTBP2	C-terminal binding protein 2	0.122
ZRANB1	zinc finger, RAN-binding domain containing 1	0.121
CSNK1D	casein kinase 1, delta	0.116
CTBP1	C-terminal binding protein 1	0.104
SH3BP4	SH3-domain binding protein 4	0.104
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.103	Mouse
FAT1	FAT tumor suppressor homolog 1 (Drosophila)	0.103
USP9X	ubiquitin specific peptidase 9, X-linked	0.102
LDB1	LIM domain binding 1	0.101
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.098
CSNK1E	casein kinase 1, epsilon	0.098
ERBB2IP	erbb2 interacting protein	0.098	Human
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.097
BBS2	Bardet-Biedl syndrome 2	0.096
MED25	mediator complex subunit 25	0.096
USP22	ubiquitin specific peptidase 22	0.087
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.085	Mouse
VASP	vasodilator-stimulated phosphoprotein	0.084	Mouse
MED24	mediator complex subunit 24	0.084
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.083
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.082
NCOA6	nuclear receptor coactivator 6	0.082
EP300	E1A binding protein p300	0.081
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.081
TJP2	tight junction protein 2 (zona occludens 2)	0.080
TAF4	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa	0.080
TSC1	tuberous sclerosis 1	0.080	Mouse
ESR1	estrogen receptor 1	0.078
ORC6	origin recognition complex, subunit 6	0.076
AKIP1	A kinase (PRKA) interacting protein 1	0.071
BMP7	bone morphogenetic protein 7	0.064
WASF1	WAS protein family, member 1	0.061
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.061
BAIAP2	BAI1-associated protein 2	0.060
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.060
HMOX2	heme oxygenase (decycling) 2	0.060
SGSM2	small G protein signaling modulator 2	0.058
EPAS1	endothelial PAS domain protein 1	0.058
BBS9	Bardet-Biedl syndrome 9	0.058
PBRM1	polybromo 1	0.058
MTA1	metastasis associated 1	0.058
NCF1	neutrophil cytosolic factor 1	0.058
STRN3	striatin, calmodulin binding protein 3	0.058
BMP2	bone morphogenetic protein 2	0.057
FZD1	frizzled homolog 1 (Drosophila)	0.057	Mouse
ZMYND11	zinc finger, MYND-type containing 11	0.056
KIAA1377	KIAA1377	0.056
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.056
WT1	Wilms tumor 1	0.055
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.055
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.055
WNT5A	wingless-type MMTV integration site family, member 5A	0.055	Mouse
LGALS8	lectin, galactoside-binding, soluble, 8	0.054
SP1	Sp1 transcription factor	0.054
SMAD4	SMAD family member 4	0.054
TFAP2C	transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)	0.054
CRMP1	collapsin response mediator protein 1	0.054
FHL1	four and a half LIM domains 1	0.053
NCOR1	nuclear receptor corepressor 1	0.052
KIF14	kinesin family member 14	0.051
CHD4	chromodomain helicase DNA binding protein 4	0.051
BBS1	Bardet-Biedl syndrome 1	0.051
MCC	mutated in colorectal cancers	0.051
PRKAR2B	protein kinase, cAMP-dependent, regulatory, type II, beta	0.050
GSK3B	glycogen synthase kinase 3 beta	0.050
PJA2	praja ring finger 2	0.049
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.048
TRIP6	thyroid hormone receptor interactor 6	0.048
MED15	mediator complex subunit 15	0.048
CEP164	centrosomal protein 164kDa	0.047
MARCKS	myristoylated alanine-rich protein kinase C substrate	0.046
WNT3A	wingless-type MMTV integration site family, member 3A	0.046
RCN3	reticulocalbin 3, EF-hand calcium binding domain	0.046
ZNF746	zinc finger protein 746	0.045
SEC24A	SEC24 family, member A (S. cerevisiae)	0.045
BBS10	Bardet-Biedl syndrome 10	0.044
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.044
TTC8	tetratricopeptide repeat domain 8	0.044
TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	0.043
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.043
TADA2A	transcriptional adaptor 2A	0.043
SKIL	SKI-like oncogene	0.043
DEDD	death effector domain containing	0.042
ZYX	zyxin	0.042
NFIX	nuclear factor I/X (CCAAT-binding transcription factor)	0.042
LMAN1	lectin, mannose-binding, 1	0.042
GLI3	GLI family zinc finger 3	0.042
ATXN1	ataxin 1	0.041
KCTD1	potassium channel tetramerisation domain containing 1	0.041
PUM1	pumilio homolog 1 (Drosophila)	0.040
KDM2A	lysine (K)-specific demethylase 2A	0.040
FAM193A	family with sequence similarity 193, member A	0.040
SOS1	son of sevenless homolog 1 (Drosophila)	0.040
CLASP2	cytoplasmic linker associated protein 2	0.040
TES	testis derived transcript (3 LIM domains)	0.040	Human
ZC3H12A	zinc finger CCCH-type containing 12A	0.040
RXRB	retinoid X receptor, beta	0.039
RANBP9	RAN binding protein 9	0.039
SEMA4A	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A	0.039
SHOC2	soc-2 suppressor of clear homolog (C. elegans)	0.038
MLF1IP	MLF1 interacting protein	0.038
SLK	STE20-like kinase	0.038
BCL6	B-cell CLL/lymphoma 6	0.038
MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))	0.038
ANKRD28	ankyrin repeat domain 28	0.037
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.037
EPS8	epidermal growth factor receptor pathway substrate 8	0.037
BMPR1A	bone morphogenetic protein receptor, type IA	0.037
C10orf54	chromosome 10 open reading frame 54	0.037
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.036
BBS7	Bardet-Biedl syndrome 7	0.036
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.036
CPSF7	cleavage and polyadenylation specific factor 7, 59kDa	0.036
NUMA1	nuclear mitotic apparatus protein 1	0.035
GLIS3	GLIS family zinc finger 3	0.035
CNN2	calponin 2	0.035
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.035
RTKN	rhotekin	0.034
DMRTB1	DMRT-like family B with proline-rich C-terminal, 1	0.034
SETD7	SET domain containing (lysine methyltransferase) 7	0.034
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.034
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.034
INTS1	integrator complex subunit 1	0.034
ZNF512B	zinc finger protein 512B	0.034
BCLAF1	BCL2-associated transcription factor 1	0.034
AKAP11	A kinase (PRKA) anchor protein 11	0.034
GATAD2B	GATA zinc finger domain containing 2B	0.033
PRKAR2A	protein kinase, cAMP-dependent, regulatory, type II, alpha	0.033
TCF21	transcription factor 21	0.033
BICD1	bicaudal D homolog 1 (Drosophila)	0.033
PUM2	pumilio homolog 2 (Drosophila)	0.033
NRIP1	nuclear receptor interacting protein 1	0.032
PICALM	phosphatidylinositol binding clathrin assembly protein	0.032
FBXO3	F-box protein 3	0.032
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.032
TRIM33	tripartite motif containing 33	0.032
ANKRD17	ankyrin repeat domain 17	0.032
LDB2	LIM domain binding 2	0.032
ASCC2	activating signal cointegrator 1 complex subunit 2	0.031
HES1	hairy and enhancer of split 1, (Drosophila)	0.031
PAX6	paired box 6	0.031
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.031
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.030
SIK3	SIK family kinase 3	0.030
ZNF217	zinc finger protein 217	0.030
POU3F2	POU class 3 homeobox 2	0.030
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.030
NFIB	nuclear factor I/B	0.030
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.030
HERC1	hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1	0.030
SEPT7	septin 7	0.029
QPRT	quinolinate phosphoribosyltransferase	0.029
DOCK9	dedicator of cytokinesis 9	0.029
KIF5B	kinesin family member 5B	0.029
ITGB1BP2	integrin beta 1 binding protein (melusin) 2	0.029
FERMT2	fermitin family member 2	0.029
CENPJ	centromere protein J	0.029
CHRD	chordin	0.029
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.029
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.028
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.028
USP24	ubiquitin specific peptidase 24	0.028
MED13	mediator complex subunit 13	0.028
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.028
C9orf100	chromosome 9 open reading frame 100	0.028
FNDC1	fibronectin type III domain containing 1	0.028
BAHD1	bromo adjacent homology domain containing 1	0.027
C3orf10	chromosome 3 open reading frame 10	0.027
CHERP	calcium homeostasis endoplasmic reticulum protein	0.027
PFN1	profilin 1	0.027	Mouse
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.027
LIMK1	LIM domain kinase 1	0.027
HDAC2	histone deacetylase 2	0.027
MED29	mediator complex subunit 29	0.027
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.027
ARL6	ADP-ribosylation factor-like 6	0.027
LASP1	LIM and SH3 protein 1	0.027
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.027
RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2	0.027
TAOK1	TAO kinase 1	0.026
SNAPC4	small nuclear RNA activating complex, polypeptide 4, 190kDa	0.026
PDHX	pyruvate dehydrogenase complex, component X	0.026
SOCS7	suppressor of cytokine signaling 7	0.026
PELI3	pellino homolog 3 (Drosophila)	0.026
KIF15	kinesin family member 15	0.026
ARFGEF1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	0.026
COL2A1	collagen, type II, alpha 1	0.026
KDM3B	lysine (K)-specific demethylase 3B	0.026
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.026
AKAP1	A kinase (PRKA) anchor protein 1	0.026
MCM3AP	minichromosome maintenance complex component 3 associated protein	0.026
AARSD1	alanyl-tRNA synthetase domain containing 1	0.026
FBLN1	fibulin 1	0.026
DST	dystonin	0.026
MTMR4	myotubularin related protein 4	0.026
TNFSF11	tumor necrosis factor (ligand) superfamily, member 11	0.025
FSTL1	follistatin-like 1	0.025
PITX1	paired-like homeodomain 1	0.025
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.025
ZNF692	zinc finger protein 692	0.025
BRD4	bromodomain containing 4	0.025
GMEB1	glucocorticoid modulatory element binding protein 1	0.025
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.025
CENPE	centromere protein E, 312kDa	0.025
KIAA1267	KIAA1267	0.025
MEF2C	myocyte enhancer factor 2C	0.025
CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)	0.025
CLK2	CDC-like kinase 2	0.025
PHF12	PHD finger protein 12	0.025
ZNF263	zinc finger protein 263	0.025
SREBF2	sterol regulatory element binding transcription factor 2	0.025
PAX2	paired box 2	0.024	Mouse
MAPK7	mitogen-activated protein kinase 7	0.024
CADM4	cell adhesion molecule 4	0.024
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.024
FAM110C	family with sequence similarity 110, member C	0.024
DDI1	DNA-damage inducible 1 homolog 1 (S. cerevisiae)	0.024
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.024
BRD3	bromodomain containing 3	0.024
MSX1	msh homeobox 1	0.024
CENPI	centromere protein I	0.024
ST6GALNAC2	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2	0.024
ACTN1	actinin, alpha 1	0.024
PCDH1	protocadherin 1	0.024
CARM1	coactivator-associated arginine methyltransferase 1	0.024
NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	0.024
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.024
OSTC	oligosaccharyltransferase complex subunit	0.024
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.024
PLAGL1	pleiomorphic adenoma gene-like 1	0.023
CAMSAP1L1	calmodulin regulated spectrin-associated protein 1-like 1	0.023
TSC22D4	TSC22 domain family, member 4	0.023
RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	0.023
RGL2	ral guanine nucleotide dissociation stimulator-like 2	0.023
PRDM4	PR domain containing 4	0.023
MXRA5	matrix-remodelling associated 5	0.023
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.023
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.023
PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta	0.023
GSK3A	glycogen synthase kinase 3 alpha	0.023
SAP130	Sin3A-associated protein, 130kDa	0.023
ENAH	enabled homolog (Drosophila)	0.023	Mouse
RARB	retinoic acid receptor, beta	0.023
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.023
ARHGAP5	Rho GTPase activating protein 5	0.022
GPR161	G protein-coupled receptor 161	0.022
SUPT3H	suppressor of Ty 3 homolog (S. cerevisiae)	0.022
SLX4	SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)	0.022
HIC1	hypermethylated in cancer 1	0.022
ELF4	E74-like factor 4 (ets domain transcription factor)	0.022
HDAC1	histone deacetylase 1	0.022
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.022
NDRG1	N-myc downstream regulated 1	0.022
DPPA2	developmental pluripotency associated 2	0.022
CARD11	caspase recruitment domain family, member 11	0.022
VIP	vasoactive intestinal peptide	0.022
LAMA5	laminin, alpha 5	0.022
EPS15	epidermal growth factor receptor pathway substrate 15	0.022
GLI2	GLI family zinc finger 2	0.022
DNAJC13	DnaJ (Hsp40) homolog, subfamily C, member 13	0.022
USP21	ubiquitin specific peptidase 21	0.022
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.022
NKD2	naked cuticle homolog 2 (Drosophila)	0.022
TGFB2	transforming growth factor, beta 2	0.022
KDM5C	lysine (K)-specific demethylase 5C	0.022
NCK1	NCK adaptor protein 1	0.022
PLXNB1	plexin B1	0.022
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.022
TADA3	transcriptional adaptor 3	0.022
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.022
ZMYM3	zinc finger, MYM-type 3	0.022
MNS1	meiosis-specific nuclear structural 1	0.022
COL12A1	collagen, type XII, alpha 1	0.021
ZBTB8A	zinc finger and BTB domain containing 8A	0.021
CHD8	chromodomain helicase DNA binding protein 8	0.021
CIC	capicua homolog (Drosophila)	0.021
NCOR2	nuclear receptor corepressor 2	0.021
ARHGAP11A	Rho GTPase activating protein 11A	0.021
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.021
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.021
SNX18	sorting nexin 18	0.021
F3	coagulation factor III (thromboplastin, tissue factor)	0.021
GIGYF2	GRB10 interacting GYF protein 2	0.021
AKAP12	A kinase (PRKA) anchor protein 12	0.021
WDFY3	WD repeat and FYVE domain containing 3	0.021
STK36	serine/threonine kinase 36	0.021
SULF1	sulfatase 1	0.021
ATXN2	ataxin 2	0.021
FZD6	frizzled homolog 6 (Drosophila)	0.021	Mouse
PERP	PERP, TP53 apoptosis effector	0.021
FAM110A	family with sequence similarity 110, member A	0.021
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.021
POLQ	polymerase (DNA directed), theta	0.021
BAG3	BCL2-associated athanogene 3	0.021
GAS1	growth arrest-specific 1	0.021
SFRP4	secreted frizzled-related protein 4	0.021
MBNL1	muscleblind-like (Drosophila)	0.021
RBPMS	RNA binding protein with multiple splicing	0.021
NOL3	nucleolar protein 3 (apoptosis repressor with CARD domain)	0.021
ZMIZ1	zinc finger, MIZ-type containing 1	0.021
IGSF3	immunoglobulin superfamily, member 3	0.021
SPOP	speckle-type POZ protein	0.021
SURF4	surfeit 4	0.021
ACACA	acetyl-CoA carboxylase alpha	0.021
NPIP	nuclear pore complex interacting protein	0.021
HSPA2	heat shock 70kDa protein 2	0.020
DOCK1	dedicator of cytokinesis 1	0.020
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.020
TPM4	tropomyosin 4	0.020
CXXC5	CXXC finger protein 5	0.020
MYO10	myosin X	0.020
AKAP10	A kinase (PRKA) anchor protein 10	0.020
PPP6R3	protein phosphatase 6, regulatory subunit 3	0.020
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.020
HEMGN	hemogen	0.020
BCL3	B-cell CLL/lymphoma 3	0.020
CASC3	cancer susceptibility candidate 3	0.020
VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C	0.020
IPO13	importin 13	0.020
TMED7	transmembrane emp24 protein transport domain containing 7	0.020
CRABP2	cellular retinoic acid binding protein 2	0.020
CHD3	chromodomain helicase DNA binding protein 3	0.020
MACF1	microtubule-actin crosslinking factor 1	0.020
PGRMC1	progesterone receptor membrane component 1	0.020
KIAA1191	KIAA1191	0.020
PRRC2B	proline-rich coiled-coil 2B	0.020
CFL2	cofilin 2 (muscle)	0.020
CHD7	chromodomain helicase DNA binding protein 7	0.020
BTBD7	BTB (POZ) domain containing 7	0.020
MYH10	myosin, heavy chain 10, non-muscle	0.020
NSMAF	neutral sphingomyelinase (N-SMase) activation associated factor	0.020
FZD8	frizzled homolog 8 (Drosophila)	0.020
COMP	cartilage oligomeric matrix protein	0.020
TNKS2	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2	0.020
MTA2	metastasis associated 1 family, member 2	0.020
BANP	BTG3 associated nuclear protein	0.020
PDE4DIP	phosphodiesterase 4D interacting protein	0.020
CDK19	cyclin-dependent kinase 19	0.020
INPPL1	inositol polyphosphate phosphatase-like 1	0.020
GATA5	GATA binding protein 5	0.020
FGF2	fibroblast growth factor 2 (basic)	0.020
HNF4A	hepatocyte nuclear factor 4, alpha	0.020
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.020	Mouse
FBRSL1	fibrosin-like 1	0.020
KIF3B	kinesin family member 3B	0.019
APOBEC3B	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B	0.019
GJA1	gap junction protein, alpha 1, 43kDa	0.019
MCFD2	multiple coagulation factor deficiency 2	0.019
ATP2B1	ATPase, Ca++ transporting, plasma membrane 1	0.019
FOXC1	forkhead box C1	0.019
MEN1	multiple endocrine neoplasia I	0.019
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.019
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.019
RNF31	ring finger protein 31	0.019
HDAC10	histone deacetylase 10	0.019
FZD7	frizzled homolog 7 (Drosophila)	0.019
ERF	Ets2 repressor factor	0.019
PPAP2B	phosphatidic acid phosphatase type 2B	0.019
GAPVD1	GTPase activating protein and VPS9 domains 1	0.019
RYR2	ryanodine receptor 2 (cardiac)	0.019
CLASRP	CLK4-associating serine/arginine rich protein	0.019
RANBP10	RAN binding protein 10	0.019
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.019
CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	0.019
BRAP	BRCA1 associated protein	0.019
SOX2	SRY (sex determining region Y)-box 2	0.019
COL1A1	collagen, type I, alpha 1	0.019
LAMC1	laminin, gamma 1 (formerly LAMB2)	0.019
CHIC2	cysteine-rich hydrophobic domain 2	0.019
CIT	citron (rho-interacting, serine/threonine kinase 21)	0.019
PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide	0.019
PIGA	phosphatidylinositol glycan anchor biosynthesis, class A	0.019
SIX4	SIX homeobox 4	0.019
CALU	calumenin	0.019
RPRD2	regulation of nuclear pre-mRNA domain containing 2	0.019
GLIS2	GLIS family zinc finger 2	0.018
SSBP3	single stranded DNA binding protein 3	0.018
AKAP8L	A kinase (PRKA) anchor protein 8-like	0.018
PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)	0.018
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.018
SOX9	SRY (sex determining region Y)-box 9	0.018
FBXO30	F-box protein 30	0.018
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.018
TINAGL1	tubulointerstitial nephritis antigen-like 1	0.018
NEK7	NIMA (never in mitosis gene a)-related kinase 7	0.018
DAPK1	death-associated protein kinase 1	0.018
IRAK3	interleukin-1 receptor-associated kinase 3	0.018
MARK2	MAP/microtubule affinity-regulating kinase 2	0.018
KRTAP4-12	keratin associated protein 4-12	0.018
ZFYVE26	zinc finger, FYVE domain containing 26	0.018
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.018
SDCCAG3	serologically defined colon cancer antigen 3	0.018
ADARB1	adenosine deaminase, RNA-specific, B1	0.018
USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	0.018
ZC3H7A	zinc finger CCCH-type containing 7A	0.018
PRKCZ	protein kinase C, zeta	0.018
TLK2	tousled-like kinase 2	0.018
ZNF609	zinc finger protein 609	0.018
ZCCHC14	zinc finger, CCHC domain containing 14	0.018
PYGO2	pygopus homolog 2 (Drosophila)	0.018
PTCH1	patched 1	0.018
ZBED1	zinc finger, BED-type containing 1	0.018
ZFP106	zinc finger protein 106 homolog (mouse)	0.018
EIF3C	eukaryotic translation initiation factor 3, subunit C	0.018
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.018
TNP2	transition protein 2 (during histone to protamine replacement)	0.018
C2orf44	chromosome 2 open reading frame 44	0.018
KIAA1522	KIAA1522	0.018
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.018
GPSM2	G-protein signaling modulator 2	0.018
EXOC5	exocyst complex component 5	0.018
FOXD1	forkhead box D1	0.018
PDGFRL	platelet-derived growth factor receptor-like	0.018
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.018
TM9SF2	transmembrane 9 superfamily member 2	0.018
GPC4	glypican 4	0.018
TWIST2	twist homolog 2 (Drosophila)	0.018
EP400	E1A binding protein p400	0.018
COL11A1	collagen, type XI, alpha 1	0.018
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.017
PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	0.017
KCTD15	potassium channel tetramerisation domain containing 15	0.017
ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1	0.017
HMGB2	high mobility group box 2	0.017
WDR48	WD repeat domain 48	0.017
SDC2	syndecan 2	0.017
OCLN	occludin	0.017
NIN	ninein (GSK3B interacting protein)	0.017
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.017
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.017
IL1RAP	interleukin 1 receptor accessory protein	0.017
JAG1	jagged 1	0.017
TAB3	TGF-beta activated kinase 1/MAP3K7 binding protein 3	0.017
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.017
PNRC1	proline-rich nuclear receptor coactivator 1	0.017
HOXA5	homeobox A5	0.017
IRX5	iroquois homeobox 5	0.017
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.017
MEF2A	myocyte enhancer factor 2A	0.017
TIFA	TRAF-interacting protein with forkhead-associated domain	0.017
SHOX2	short stature homeobox 2	0.017
SNAI2	snail homolog 2 (Drosophila)	0.017
MED26	mediator complex subunit 26	0.017
STT3A	STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)	0.017
SPEN	spen homolog, transcriptional regulator (Drosophila)	0.017
TMEM44	transmembrane protein 44	0.017
CELSR2	cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)	0.017
PHKA2	phosphorylase kinase, alpha 2 (liver)	0.017
AKAP7	A kinase (PRKA) anchor protein 7	0.017
ATP11B	ATPase, class VI, type 11B	0.017
SEPT10	septin 10	0.017
LAMA3	laminin, alpha 3	0.017
THAP11	THAP domain containing 11	0.017
ZFPM1	zinc finger protein, multitype 1	0.017
NELL2	NEL-like 2 (chicken)	0.017
SEC31A	SEC31 homolog A (S. cerevisiae)	0.017
CKAP2	cytoskeleton associated protein 2	0.017
RDX	radixin	0.017
ACVR1	activin A receptor, type I	0.017
WNT4	wingless-type MMTV integration site family, member 4	0.017
TMEM123	transmembrane protein 123	0.017
HOXA9	homeobox A9	0.017
ACY3	aspartoacylase (aminocyclase) 3	0.017
SLC38A2	solute carrier family 38, member 2	0.017
BRD1	bromodomain containing 1	0.017
EDNRA	endothelin receptor type A	0.017
INPP5E	inositol polyphosphate-5-phosphatase, 72 kDa	0.017
BBS12	Bardet-Biedl syndrome 12	0.017
KCTD9	potassium channel tetramerisation domain containing 9	0.017
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.017
COL1A2	collagen, type I, alpha 2	0.017
C19orf46	chromosome 19 open reading frame 46	0.017
HOXD13	homeobox D13	0.017
HOXA11	homeobox A11	0.017
MN1	meningioma (disrupted in balanced translocation) 1	0.017
NAV3	neuron navigator 3	0.017
BRIP1	BRCA1 interacting protein C-terminal helicase 1	0.017
CYFIP1	cytoplasmic FMR1 interacting protein 1	0.017
LZTS2	leucine zipper, putative tumor suppressor 2	0.017
C2orf88	chromosome 2 open reading frame 88	0.017
PLK4	polo-like kinase 4	0.017
CBX4	chromobox homolog 4	0.017
POGZ	pogo transposable element with ZNF domain	0.017
APPL2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2	0.017
RCOR1	REST corepressor 1	0.017
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.017
RAD54B	RAD54 homolog B (S. cerevisiae)	0.017
DSG2	desmoglein 2	0.017
CSNK1G3	casein kinase 1, gamma 3	0.017
ZNF576	zinc finger protein 576	0.017
TFG	TRK-fused gene	0.017
FZD5	frizzled homolog 5 (Drosophila)	0.017
CALD1	caldesmon 1	0.017
RBM5	RNA binding motif protein 5	0.017
CLINT1	clathrin interactor 1	0.017
FZD2	frizzled homolog 2 (Drosophila)	0.016
MTA3	metastasis associated 1 family, member 3	0.016
HOXC5	homeobox C5	0.016
CAPRIN2	caprin family member 2	0.016
TUBB2B	tubulin, beta 2B	0.016
NHS	Nance-Horan syndrome (congenital cataracts and dental anomalies)	0.016
CENPQ	centromere protein Q	0.016
IRX3	iroquois homeobox 3	0.016
RYK	RYK receptor-like tyrosine kinase	0.016
GATA4	GATA binding protein 4	0.016
MUS81	MUS81 endonuclease homolog (S. cerevisiae)	0.016
GIT1	G protein-coupled receptor kinase interacting ArfGAP 1	0.016
PRUNE2	prune homolog 2 (Drosophila)	0.016
HMX1	H6 family homeobox 1	0.016
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.016
PFDN1	prefoldin subunit 1	0.016
TNFAIP8L1	tumor necrosis factor, alpha-induced protein 8-like 1	0.016
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.016
ELF2	E74-like factor 2 (ets domain transcription factor)	0.016
TMEM45A	transmembrane protein 45A	0.016
PPARA	peroxisome proliferator-activated receptor alpha	0.016
RBBP8	retinoblastoma binding protein 8	0.016
PTBP2	polypyrimidine tract binding protein 2	0.016
JMJD1C	jumonji domain containing 1C	0.016
CPOX	coproporphyrinogen oxidase	0.016
ANTXR2	anthrax toxin receptor 2	0.016
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.016
PCNT	pericentrin	0.016
PRICKLE1	prickle homolog 1 (Drosophila)	0.016
MYO6	myosin VI	0.016
ADAM12	ADAM metallopeptidase domain 12	0.016
SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)	0.016
ARHGEF19	Rho guanine nucleotide exchange factor (GEF) 19	0.016
NR2F6	nuclear receptor subfamily 2, group F, member 6	0.016
SAP30L	SAP30-like	0.016
SFRP1	secreted frizzled-related protein 1	0.016	Mouse
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.016
IRX4	iroquois homeobox 4	0.016
COL3A1	collagen, type III, alpha 1	0.016
SLIT2	slit homolog 2 (Drosophila)	0.016
FGFR3	fibroblast growth factor receptor 3	0.016
FOXF2	forkhead box F2	0.016
EHMT1	euchromatic histone-lysine N-methyltransferase 1	0.016
CDK5RAP2	CDK5 regulatory subunit associated protein 2	0.016
ZNF76	zinc finger protein 76	0.016
RPAP1	RNA polymerase II associated protein 1	0.016
ERC1	ELKS/RAB6-interacting/CAST family member 1	0.016
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.016
C12orf48	chromosome 12 open reading frame 48	0.016
FGD1	FYVE, RhoGEF and PH domain containing 1	0.016
CLDN7	claudin 7	0.016
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.016
PRKX	protein kinase, X-linked	0.016
BCL9	B-cell CLL/lymphoma 9	0.016
PIK3C2A	phosphoinositide-3-kinase, class 2, alpha polypeptide	0.016
NOTCH3	notch 3	0.016
CDYL	chromodomain protein, Y-like	0.016
SOCS1	suppressor of cytokine signaling 1	0.016
TBC1D14	TBC1 domain family, member 14	0.016
SIM2	single-minded homolog 2 (Drosophila)	0.016
SEPT11	septin 11	0.016
HOXD11	homeobox D11	0.016
HOXA10	homeobox A10	0.016
ZEB1	zinc finger E-box binding homeobox 1	0.016
ALS2	amyotrophic lateral sclerosis 2 (juvenile)	0.016
BAD	BCL2-associated agonist of cell death	0.016
NAT9	N-acetyltransferase 9 (GCN5-related, putative)	0.016
CPSF1	cleavage and polyadenylation specific factor 1, 160kDa	0.016
GATA2	GATA binding protein 2	0.016
RBM11	RNA binding motif protein 11	0.016
ROR1	receptor tyrosine kinase-like orphan receptor 1	0.016
MECOM	MDS1 and EVI1 complex locus	0.016
LHX1	LIM homeobox 1	0.016
MEX3B	mex-3 homolog B (C. elegans)	0.016
PLAG1	pleiomorphic adenoma gene 1	0.016
FEM1B	fem-1 homolog b (C. elegans)	0.016
POSTN	periostin, osteoblast specific factor	0.016
NNT	nicotinamide nucleotide transhydrogenase	0.016
PITX2	paired-like homeodomain 2	0.016
PMP22	peripheral myelin protein 22	0.016
CNN3	calponin 3, acidic	0.016
WDR44	WD repeat domain 44	0.016
MYST4	MYST histone acetyltransferase (monocytic leukemia) 4	0.016
CEP55	centrosomal protein 55kDa	0.016
PPP1R12A	protein phosphatase 1, regulatory (inhibitor) subunit 12A	0.016
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.016
SPTBN1	spectrin, beta, non-erythrocytic 1	0.016
NCOA3	nuclear receptor coactivator 3	0.016
PRKRIR	protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)	0.016
SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	0.016
ADCY9	adenylate cyclase 9	0.016
TPBG	trophoblast glycoprotein	0.016
CYR61	cysteine-rich, angiogenic inducer, 61	0.016
SLC20A1	solute carrier family 20 (phosphate transporter), member 1	0.016
HCFC1	host cell factor C1 (VP16-accessory protein)	0.016
CDK10	cyclin-dependent kinase 10	0.016
FBXO25	F-box protein 25	0.016
LSR	lipolysis stimulated lipoprotein receptor	0.016
RNF38	ring finger protein 38	0.016
RADIL	Ras association and DIL domains	0.016
OXSR1	oxidative-stress responsive 1	0.015
MDFI	MyoD family inhibitor	0.015
ARHGEF11	Rho guanine nucleotide exchange factor (GEF) 11	0.015
MEX3C	mex-3 homolog C (C. elegans)	0.015
WIF1	WNT inhibitory factor 1	0.015
MORC3	MORC family CW-type zinc finger 3	0.015
IGFBP3	insulin-like growth factor binding protein 3	0.015
IL1F7	interleukin 1 family, member 7 (zeta)	0.015
CENPF	centromere protein F, 350/400kDa (mitosin)	0.015
MSX2	msh homeobox 2	0.015
PROX1	prospero homeobox 1	0.015
STK39	serine threonine kinase 39	0.015
PAX1	paired box 1	0.015
WDTC1	WD and tetratricopeptide repeats 1	0.015
ATAD5	ATPase family, AAA domain containing 5	0.015
SOX4	SRY (sex determining region Y)-box 4	0.015
PDLIM7	PDZ and LIM domain 7 (enigma)	0.015
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.015
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.015	Mouse
DLX1	distal-less homeobox 1	0.015
FAM46D	family with sequence similarity 46, member D	0.015
SMARCD3	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3	0.015
HECW2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	0.015
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.015
ARIH1	ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)	0.015
CAV1	caveolin 1, caveolae protein, 22kDa	0.015
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.015
ZCCHC24	zinc finger, CCHC domain containing 24	0.015
XPC	xeroderma pigmentosum, complementation group C	0.015
FBLN2	fibulin 2	0.015
RALGDS	ral guanine nucleotide dissociation stimulator	0.015
WWC1	WW and C2 domain containing 1	0.015
ANKHD1-EIF4EBP3	ANKHD1-EIF4EBP3 readthrough	0.015
SCAP	SREBF chaperone	0.015
HES6	hairy and enhancer of split 6 (Drosophila)	0.015
BTBD2	BTB (POZ) domain containing 2	0.015
PSAP	prosaposin	0.015
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.015
TRIM24	tripartite motif containing 24	0.015
IL24	interleukin 24	0.015
DAZAP1	DAZ associated protein 1	0.015
PER1	period homolog 1 (Drosophila)	0.015
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.015
TPD52L1	tumor protein D52-like 1	0.015
PRR12	proline rich 12	0.015
DAAM1	dishevelled associated activator of morphogenesis 1	0.015
SOX12	SRY (sex determining region Y)-box 12	0.015
ATXN7	ataxin 7	0.015
CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	0.015
LRRC14	leucine rich repeat containing 14	0.015
CDK9	cyclin-dependent kinase 9	0.015
ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	0.015
IGF2BP1	insulin-like growth factor 2 mRNA binding protein 1	0.015
FAM20B	family with sequence similarity 20, member B	0.015
HOXD9	homeobox D9	0.015
RP2	retinitis pigmentosa 2 (X-linked recessive)	0.015
FAM176A	family with sequence similarity 176, member A	0.015
EN2	engrailed homeobox 2	0.015
COL4A6	collagen, type IV, alpha 6	0.015
NPAS1	neuronal PAS domain protein 1	0.015
ETV4	ets variant 4	0.015
RHPN2	rhophilin, Rho GTPase binding protein 2	0.015
MFGE8	milk fat globule-EGF factor 8 protein	0.015
TGFB1	transforming growth factor, beta 1	0.015
EPHB3	EPH receptor B3	0.015
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.015
OXCT1	3-oxoacid CoA transferase 1	0.015
SAP30	Sin3A-associated protein, 30kDa	0.015
MYH11	myosin, heavy chain 11, smooth muscle	0.015
PTPRF	protein tyrosine phosphatase, receptor type, F	0.015
CDX2	caudal type homeobox 2	0.015
PDPK1	3-phosphoinositide dependent protein kinase-1	0.015
ZBTB48	zinc finger and BTB domain containing 48	0.015
ISL1	ISL LIM homeobox 1	0.015
PCDH18	protocadherin 18	0.015
ZFP36L2	zinc finger protein 36, C3H type-like 2	0.015
KIFAP3	kinesin-associated protein 3	0.015
POU5F1	POU class 5 homeobox 1	0.015
ZBTB10	zinc finger and BTB domain containing 10	0.015
PAX9	paired box 9	0.015
OR5AR1	olfactory receptor, family 5, subfamily AR, member 1	0.015
ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5	0.015
ROCK1	Rho-associated, coiled-coil containing protein kinase 1	0.015
RXRG	retinoid X receptor, gamma	0.015
DTX2	deltex homolog 2 (Drosophila)	0.015
EPHB4	EPH receptor B4	0.015
LZTFL1	leucine zipper transcription factor-like 1	0.015
ZNF165	zinc finger protein 165	0.015
NACC2	NACC family member 2, BEN and BTB (POZ) domain containing	0.015
CELF2	CUGBP, Elav-like family member 2	0.015
KIF20B	kinesin family member 20B	0.015	Mouse
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	0.015
COL15A1	collagen, type XV, alpha 1	0.015
GTF2I	general transcription factor IIi	0.015
UBAP2	ubiquitin associated protein 2	0.015
TNP1	transition protein 1 (during histone to protamine replacement)	0.015
MYO1B	myosin IB	0.015
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.015
ASXL1	additional sex combs like 1 (Drosophila)	0.015
CCNO	cyclin O	0.015
BNC1	basonuclin 1	0.015
QKI	quaking homolog, KH domain RNA binding (mouse)	0.015
PLK2	polo-like kinase 2	0.015
ARHGAP21	Rho GTPase activating protein 21	0.015
KIAA1370	KIAA1370	0.015
AKAP5	A kinase (PRKA) anchor protein 5	0.015
EN1	engrailed homeobox 1	0.015
RIPK4	receptor-interacting serine-threonine kinase 4	0.015
ICK	intestinal cell (MAK-like) kinase	0.015
AARS2	alanyl-tRNA synthetase 2, mitochondrial (putative)	0.015
COG5	component of oligomeric golgi complex 5	0.015
ZIC2	Zic family member 2 (odd-paired homolog, Drosophila)	0.015	Mouse
LHX2	LIM homeobox 2	0.015	Mouse
FBXO46	F-box protein 46	0.015
EYA2	eyes absent homolog 2 (Drosophila)	0.015