IMP: Integrative Multi-species Prediction

Homo sapiens

83 genes annotated in human

Multi-species View

negative regulation of cell growth

GO:0030308

Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of cell growth"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of cell growth" (in gray)

Name	Description	Probability	Func Analog Organism
TP53	tumor protein p53	0.996
SMAD2	SMAD family member 2	0.977	Human
SMURF2	SMAD specific E3 ubiquitin protein ligase 2	0.955
CREBBP	CREB binding protein	0.934
SMAD4	SMAD family member 4	0.921
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.911
SMAD3	SMAD family member 3	0.864
CDK6	cyclin-dependent kinase 6	0.858
SMAD7	SMAD family member 7	0.776	Human
CCND1	cyclin D1	0.775
SMAD1	SMAD family member 1	0.663	Human
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.641
CDK4	cyclin-dependent kinase 4	0.636
TSC2	tuberous sclerosis 2	0.591	Fly
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.589
FGF1	fibroblast growth factor 1 (acidic)	0.553
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.529
AR	androgen receptor	0.524
RARA	retinoic acid receptor, alpha	0.518
CCND3	cyclin D3	0.514
SMAD5	SMAD family member 5	0.485	Human
HDAC2	histone deacetylase 2	0.483
TGFBR1	transforming growth factor, beta receptor 1	0.454	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.431	Human
DAXX	death-domain associated protein	0.424
SMAD9	SMAD family member 9	0.419	Human
SKIL	SKI-like oncogene	0.410
FKBP1A	FK506 binding protein 1A, 12kDa	0.387
SKI	v-ski sarcoma viral oncogene homolog (avian)	0.385
VEGFA	vascular endothelial growth factor A	0.378
HSPA1B	heat shock 70kDa protein 1B	0.367
HSPA8	heat shock 70kDa protein 8	0.356	Human
TGFB3	transforming growth factor, beta 3	0.354
NR2E3	nuclear receptor subfamily 2, group E, member 3	0.350
ABI2	abl-interactor 2	0.341
HSPA1A	heat shock 70kDa protein 1A	0.327
TGFB1	transforming growth factor, beta 1	0.322
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.296
BAG3	BCL2-associated athanogene 3	0.286
BMP2	bone morphogenetic protein 2	0.280
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.279
GRB10	growth factor receptor-bound protein 10	0.253
PAX3	paired box 3	0.233
NCOR2	nuclear receptor corepressor 2	0.232
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.224
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.220
RUNX1	runt-related transcription factor 1	0.211
SCHIP1	schwannomin interacting protein 1	0.204
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.203
GRB7	growth factor receptor-bound protein 7	0.199
APP	amyloid beta (A4) precursor protein	0.197
SMURF1	SMAD specific E3 ubiquitin protein ligase 1	0.193
MAST2	microtubule associated serine/threonine kinase 2	0.188
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.188	Rat
GDF5	growth differentiation factor 5	0.181	Human
CDK5	cyclin-dependent kinase 5	0.181	Mouse
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.176
SNX33	sorting nexin 33	0.174
NCOA1	nuclear receptor coactivator 1	0.172
HSPB1	heat shock 27kDa protein 1	0.171
NRP1	neuropilin 1	0.171	Human Mouse Rat
DLG1	discs, large homolog 1 (Drosophila)	0.170
CXXC5	CXXC finger protein 5	0.165
PTMA	prothymosin, alpha	0.165
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.161
RNF11	ring finger protein 11	0.159
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.149
GHR	growth hormone receptor	0.141
BMPR1B	bone morphogenetic protein receptor, type IB	0.140	Human
ATG13	ATG13 autophagy related 13 homolog (S. cerevisiae)	0.139
TFRC	transferrin receptor (p90, CD71)	0.139
EGR2	early growth response 2	0.137	Human
YAP1	Yes-associated protein 1	0.131
RBBP4	retinoblastoma binding protein 4	0.123	Human
SFRP1	secreted frizzled-related protein 1	0.122
RXRA	retinoid X receptor, alpha	0.120	Human
ENG	endoglin	0.119
RB1CC1	RB1-inducible coiled-coil 1	0.117
SMAD6	SMAD family member 6	0.117	Human
NCOA6	nuclear receptor coactivator 6	0.116
SREBF2	sterol regulatory element binding transcription factor 2	0.114
ZFYVE9	zinc finger, FYVE domain containing 9	0.113
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.112
RB1	retinoblastoma 1	0.110
SP1	Sp1 transcription factor	0.109
SH3D19	SH3 domain containing 19	0.109
HDAC1	histone deacetylase 1	0.109
KAT2B	K(lysine) acetyltransferase 2B	0.109
BCL2L1	BCL2-like 1	0.107
IRAK2	interleukin-1 receptor-associated kinase 2	0.105
FOXO3	forkhead box O3	0.105	Fly
SQSTM1	sequestosome 1	0.104
CABLES1	Cdk5 and Abl enzyme substrate 1	0.104
TFAP2A	transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)	0.104
ACVR1	activin A receptor, type I	0.102	Human
BMP7	bone morphogenetic protein 7	0.102	Human
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.101
HSPB2	heat shock 27kDa protein 2	0.101
HES1	hairy and enhancer of split 1, (Drosophila)	0.101
PGK1	phosphoglycerate kinase 1	0.100
AXIN1	axin 1	0.099
MSX1	msh homeobox 1	0.098
ATF2	activating transcription factor 2	0.097
FZD1	frizzled homolog 1 (Drosophila)	0.095	Human
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.095
IRS2	insulin receptor substrate 2	0.095
STRADA	STE20-related kinase adaptor alpha	0.093
ELK1	ELK1, member of ETS oncogene family	0.093
CDK5R1	cyclin-dependent kinase 5, regulatory subunit 1 (p35)	0.093	Mouse
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.092
FZD7	frizzled homolog 7 (Drosophila)	0.092	Human
STIP1	stress-induced-phosphoprotein 1	0.091
TBX2	T-box 2	0.090
BMP4	bone morphogenetic protein 4	0.086
CDH5	cadherin 5, type 2 (vascular endothelium)	0.086
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.086
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.086
TGFB2	transforming growth factor, beta 2	0.085
PPP5C	protein phosphatase 5, catalytic subunit	0.085
POU3F2	POU class 3 homeobox 2	0.084
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.083
SESN2	sestrin 2	0.082
RANBP9	RAN binding protein 9	0.082
APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1	0.082
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.081
COL2A1	collagen, type II, alpha 1	0.080
FGF10	fibroblast growth factor 10	0.079
EGR1	early growth response 1	0.078	Human
BAG2	BCL2-associated athanogene 2	0.078
WNT5A	wingless-type MMTV integration site family, member 5A	0.078	Mouse
HDAC11	histone deacetylase 11	0.077
DVL3	dishevelled, dsh homolog 3 (Drosophila)	0.077
SH3PXD2A	SH3 and PX domains 2A	0.076
LRP6	low density lipoprotein receptor-related protein 6	0.076
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.076
BAG1	BCL2-associated athanogene	0.076
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.075
HK2	hexokinase 2	0.075
FGF2	fibroblast growth factor 2 (basic)	0.075
HSPB8	heat shock 22kDa protein 8	0.074
ZBTB16	zinc finger and BTB domain containing 16	0.072
HSPH1	heat shock 105kDa/110kDa protein 1	0.072
CSNK1D	casein kinase 1, delta	0.071
TSC1	tuberous sclerosis 1	0.071	Fly
COPS2	COP9 constitutive photomorphogenic homolog subunit 2 (Arabidopsis)	0.070
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.070
BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	0.070
GABARAP	GABA(A) receptor-associated protein	0.069
CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)	0.069	Mouse
AKT1	v-akt murine thymoma viral oncogene homolog 1	0.066
TBC1D17	TBC1 domain family, member 17	0.066
DNM2	dynamin 2	0.066
VEGFC	vascular endothelial growth factor C	0.066
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.064
PRKG1	protein kinase, cGMP-dependent, type I	0.064
TDGF1	teratocarcinoma-derived growth factor 1	0.064
WNT3A	wingless-type MMTV integration site family, member 3A	0.063	Mouse
MED25	mediator complex subunit 25	0.063
FGFR1	fibroblast growth factor receptor 1	0.062	Fly
NME7	non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)	0.062
ZEB2	zinc finger E-box binding homeobox 2	0.062
PCDH9	protocadherin 9	0.061
ID4	inhibitor of DNA binding 4, dominant negative helix-loop-helix protein	0.061
FBLN1	fibulin 1	0.061
MAP4	microtubule-associated protein 4	0.060
PGF	placental growth factor	0.060
FOXO1	forkhead box O1	0.060	Fly
FAM46A	family with sequence similarity 46, member A	0.060
MSX2	msh homeobox 2	0.060	Human
CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)	0.060
PLCG1	phospholipase C, gamma 1	0.059
NRP2	neuropilin 2	0.059	Human
PROX1	prospero homeobox 1	0.059
AKAP12	A kinase (PRKA) anchor protein 12	0.059
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.059
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.058
INHBB	inhibin, beta B	0.058	Human
HDAC4	histone deacetylase 4	0.058
FOXF2	forkhead box F2	0.058
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.057
SNX9	sorting nexin 9	0.057
EPAS1	endothelial PAS domain protein 1	0.057	Fly
LAT	linker for activation of T cells	0.056
HEY1	hairy/enhancer-of-split related with YRPW motif 1	0.056
CPE	carboxypeptidase E	0.055
SLIT2	slit homolog 2 (Drosophila)	0.055
WWP1	WW domain containing E3 ubiquitin protein ligase 1	0.055
HNF4A	hepatocyte nuclear factor 4, alpha	0.054
WIF1	WNT inhibitory factor 1	0.054
JAG1	jagged 1	0.054
COL4A2	collagen, type IV, alpha 2	0.053
KRT5	keratin 5	0.053
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.053
HSPD1	heat shock 60kDa protein 1 (chaperonin)	0.053
EIF4A1	eukaryotic translation initiation factor 4A1	0.052
TRAP1	TNF receptor-associated protein 1	0.052
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.052
RIPK3	receptor-interacting serine-threonine kinase 3	0.051
BBS10	Bardet-Biedl syndrome 10	0.051
NEDD4	neural precursor cell expressed, developmentally down-regulated 4	0.051
PTHLH	parathyroid hormone-like hormone	0.051
SPOP	speckle-type POZ protein	0.051
IGFBP5	insulin-like growth factor binding protein 5	0.051
SIRT1	sirtuin 1	0.051
ACVR1B	activin A receptor, type IB	0.050
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.050
SPG21	spastic paraplegia 21 (autosomal recessive, Mast syndrome)	0.050
FZD8	frizzled homolog 8 (Drosophila)	0.050	Human
PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2	0.049
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.049
MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	0.049
FGF18	fibroblast growth factor 18	0.048
GABARAPL2	GABA(A) receptor-associated protein-like 2	0.047
EGLN1	egl nine homolog 1 (C. elegans)	0.047
SOX9	SRY (sex determining region Y)-box 9	0.047	Human
FAM160A2	family with sequence similarity 160, member A2	0.047
ATP5B	ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide	0.046
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.046
HDAC5	histone deacetylase 5	0.046
BMPR1A	bone morphogenetic protein receptor, type IA	0.046	Human
TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)	0.046
CUL4A	cullin 4A	0.046
COL5A1	collagen, type V, alpha 1	0.046
PHB	prohibitin	0.045
WISP1	WNT1 inducible signaling pathway protein 1	0.045
NCOA2	nuclear receptor coactivator 2	0.045
CDK2	cyclin-dependent kinase 2	0.044
SATB2	SATB homeobox 2	0.044
DYDC1	DPY30 domain containing 1	0.044
C16orf45	chromosome 16 open reading frame 45	0.044
DOCK8	dedicator of cytokinesis 8	0.043
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.043
RPS6KA6	ribosomal protein S6 kinase, 90kDa, polypeptide 6	0.043
SOX21	SRY (sex determining region Y)-box 21	0.043
MYLK	myosin light chain kinase	0.043
RBMS3	RNA binding motif, single stranded interacting protein 3	0.043
ATM	ataxia telangiectasia mutated	0.043
PPAP2B	phosphatidic acid phosphatase type 2B	0.043
CTNND1	catenin (cadherin-associated protein), delta 1	0.043
TIMP3	TIMP metallopeptidase inhibitor 3	0.042
LDLR	low density lipoprotein receptor	0.042
HK1	hexokinase 1	0.042
DPYSL4	dihydropyrimidinase-like 4	0.042
NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)	0.042
RARRES2	retinoic acid receptor responder (tazarotene induced) 2	0.041
BAX	BCL2-associated X protein	0.041
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.041
FOXC1	forkhead box C1	0.041
STRADB	STE20-related kinase adaptor beta	0.041
SALL2	sal-like 2 (Drosophila)	0.041
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.041
ZMYND11	zinc finger, MYND-type containing 11	0.041
GATA2	GATA binding protein 2	0.040
LRP1	low density lipoprotein receptor-related protein 1	0.040
DNM1	dynamin 1	0.040
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.040
WWOX	WW domain containing oxidoreductase	0.040
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.040
CNN1	calponin 1, basic, smooth muscle	0.040
ACVR2B	activin A receptor, type IIB	0.040
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.039
SOX17	SRY (sex determining region Y)-box 17	0.039
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.039
ACAN	aggrecan	0.039
DPPA4	developmental pluripotency associated 4	0.039
PDE4DIP	phosphodiesterase 4D interacting protein	0.039
STC2	stanniocalcin 2	0.039
SAP30	Sin3A-associated protein, 30kDa	0.038
NR2F1	nuclear receptor subfamily 2, group F, member 1	0.038	Human
NR4A2	nuclear receptor subfamily 4, group A, member 2	0.038
EGR3	early growth response 3	0.038	Human
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.038
MTA3	metastasis associated 1 family, member 3	0.038
CRYBB2	crystallin, beta B2	0.038
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.038
CLU	clusterin	0.037
PDIA3	protein disulfide isomerase family A, member 3	0.037
UBQLN4	ubiquilin 4	0.037
TSC22D4	TSC22 domain family, member 4	0.037
RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)	0.037
PPARG	peroxisome proliferator-activated receptor gamma	0.037	Rat
PBK	PDZ binding kinase	0.037
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.037
CCND2	cyclin D2	0.037
AXIN2	axin 2	0.036
STC1	stanniocalcin 1	0.036
CRY1	cryptochrome 1 (photolyase-like)	0.036
DOCK7	dedicator of cytokinesis 7	0.036
WFIKKN1	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1	0.036
HABP4	hyaluronan binding protein 4	0.036
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.036
DNAJB9	DnaJ (Hsp40) homolog, subfamily B, member 9	0.036
FOXF1	forkhead box F1	0.036
KDM2A	lysine (K)-specific demethylase 2A	0.036
EIF5	eukaryotic translation initiation factor 5	0.035
INCENP	inner centromere protein antigens 135/155kDa	0.035
DDIT3	DNA-damage-inducible transcript 3	0.035
HEYL	hairy/enhancer-of-split related with YRPW motif-like	0.035
MARCKSL1	MARCKS-like 1	0.035
ACP5	acid phosphatase 5, tartrate resistant	0.035
TWIST1	twist homolog 1 (Drosophila)	0.035
FGF7	fibroblast growth factor 7	0.035
ING4	inhibitor of growth family, member 4	0.035
HMX1	H6 family homeobox 1	0.035
SERTAD1	SERTA domain containing 1	0.035
LTBP2	latent transforming growth factor beta binding protein 2	0.035
SOCS5	suppressor of cytokine signaling 5	0.035
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.035
LRP5	low density lipoprotein receptor-related protein 5	0.034
DBN1	drebrin 1	0.034
CAB39	calcium binding protein 39	0.034
PCDH1	protocadherin 1	0.034
ELF5	E74-like factor 5 (ets domain transcription factor)	0.034
TNMD	tenomodulin	0.034
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.034
RARG	retinoic acid receptor, gamma	0.034
SOX7	SRY (sex determining region Y)-box 7	0.034	Human
RUNX2	runt-related transcription factor 2	0.034
COL11A1	collagen, type XI, alpha 1	0.034
SFRP4	secreted frizzled-related protein 4	0.034	Human
MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	0.034
TG	thyroglobulin	0.033
HR	hairless homolog (mouse)	0.033
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.033
BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2	0.033
POSTN	periostin, osteoblast specific factor	0.033
FSTL1	follistatin-like 1	0.033
FOXG1	forkhead box G1	0.033
TCF7L1	transcription factor 7-like 1 (T-cell specific, HMG-box)	0.033
HOXC8	homeobox C8	0.032
CITED2	Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2	0.032
YY1	YY1 transcription factor	0.032
IGFBP3	insulin-like growth factor binding protein 3	0.032
COL4A6	collagen, type IV, alpha 6	0.032
FGFR3	fibroblast growth factor receptor 3	0.032	Fly
CUL1	cullin 1	0.032
ESRRG	estrogen-related receptor gamma	0.032
NPR1	natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)	0.032
TGFB1I1	transforming growth factor beta 1 induced transcript 1	0.032
SOX5	SRY (sex determining region Y)-box 5	0.031
AURKB	aurora kinase B	0.031
ST8SIA2	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2	0.031
TP53BP2	tumor protein p53 binding protein, 2	0.031
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.031
C10orf54	chromosome 10 open reading frame 54	0.031
SKP1	S-phase kinase-associated protein 1	0.031
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.031
DCC	deleted in colorectal carcinoma	0.031
KRT6C	keratin 6C	0.031
EHF	ets homologous factor	0.031
PRRX1	paired related homeobox 1	0.031
DLX5	distal-less homeobox 5	0.030
MYOD1	myogenic differentiation 1	0.030
SOX11	SRY (sex determining region Y)-box 11	0.030	Human
ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa	0.030
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.030
ZNF205	zinc finger protein 205	0.030
RTN4	reticulon 4	0.030
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.030
C1QL1	complement component 1, q subcomponent-like 1	0.030
LNX1	ligand of numb-protein X 1	0.030
FZD2	frizzled homolog 2 (Drosophila)	0.030	Human
APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1	0.030
BAMBI	BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)	0.030
FST	follistatin	0.030
POU3F1	POU class 3 homeobox 1	0.030
FLRT2	fibronectin leucine rich transmembrane protein 2	0.030
CDKN1C	cyclin-dependent kinase inhibitor 1C (p57, Kip2)	0.030
CACNA1G	calcium channel, voltage-dependent, T type, alpha 1G subunit	0.029
PPP1R13B	protein phosphatase 1, regulatory (inhibitor) subunit 13B	0.029
COL4A3BP	collagen, type IV, alpha 3 (Goodpasture antigen) binding protein	0.029
AMOTL1	angiomotin like 1	0.029
SETDB1	SET domain, bifurcated 1	0.029
CXCL12	chemokine (C-X-C motif) ligand 12	0.029
FGF8	fibroblast growth factor 8 (androgen-induced)	0.029
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.029
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.029
MCAM	melanoma cell adhesion molecule	0.029
WNT11	wingless-type MMTV integration site family, member 11	0.029
DRD2	dopamine receptor D2	0.029
ARID1A	AT rich interactive domain 1A (SWI-like)	0.028
BTRC	beta-transducin repeat containing	0.028
IGFBP6	insulin-like growth factor binding protein 6	0.028
SULF1	sulfatase 1	0.028
ITGB8	integrin, beta 8	0.028
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.028
HSPA13	heat shock protein 70kDa family, member 13	0.028
NCOR1	nuclear receptor corepressor 1	0.028
SIX2	SIX homeobox 2	0.028
FRS2	fibroblast growth factor receptor substrate 2	0.028
EFNB3	ephrin-B3	0.028
BANP	BTG3 associated nuclear protein	0.028
THBS1	thrombospondin 1	0.028
HAS1	hyaluronan synthase 1	0.028
CAPN6	calpain 6	0.028
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.028
HBP1	HMG-box transcription factor 1	0.027
EDNRA	endothelin receptor type A	0.027
ASCC2	activating signal cointegrator 1 complex subunit 2	0.027
TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)	0.027
PCDH7	protocadherin 7	0.027
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.027
ATG16L1	ATG16 autophagy related 16-like 1 (S. cerevisiae)	0.027
LHX2	LIM homeobox 2	0.027
MXRA5	matrix-remodelling associated 5	0.027
WNT2	wingless-type MMTV integration site family member 2	0.027	Human
DLX4	distal-less homeobox 4	0.026
LAMA4	laminin, alpha 4	0.026
HSPB7	heat shock 27kDa protein family, member 7 (cardiovascular)	0.026
TUBA4A	tubulin, alpha 4a	0.026
CXCL14	chemokine (C-X-C motif) ligand 14	0.026
GAS1	growth arrest-specific 1	0.026	Mouse
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.026
CSF3	colony stimulating factor 3 (granulocyte)	0.026
LEMD3	LEM domain containing 3	0.026
LOXL2	lysyl oxidase-like 2	0.026
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.026
HMGA2	high mobility group AT-hook 2	0.026
XRCC6	X-ray repair complementing defective repair in Chinese hamster cells 6	0.026
RTN3	reticulon 3	0.026	Human
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.026
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.026
GDF10	growth differentiation factor 10	0.026	Human
CEBPD	CCAAT/enhancer binding protein (C/EBP), delta	0.026
DCP1B	DCP1 decapping enzyme homolog B (S. cerevisiae)	0.026
PITX2	paired-like homeodomain 2	0.026
HAS2	hyaluronan synthase 2	0.026
COL1A1	collagen, type I, alpha 1	0.026
TRIL	TLR4 interactor with leucine-rich repeats	0.026
SNCG	synuclein, gamma (breast cancer-specific protein 1)	0.026
PCDH17	protocadherin 17	0.026
FHL2	four and a half LIM domains 2	0.026
PCDH18	protocadherin 18	0.026
DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	0.026
GPC4	glypican 4	0.026
CUL5	cullin 5	0.026
DKK3	dickkopf homolog 3 (Xenopus laevis)	0.026
MDK	midkine (neurite growth-promoting factor 2)	0.026
EN1	engrailed homeobox 1	0.026
UBE3A	ubiquitin protein ligase E3A	0.026
CDK2AP1	cyclin-dependent kinase 2 associated protein 1	0.026
PIGA	phosphatidylinositol glycan anchor biosynthesis, class A	0.025
COL8A1	collagen, type VIII, alpha 1	0.025
CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	0.025
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.025
ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2	0.025
OLIG2	oligodendrocyte lineage transcription factor 2	0.025
SCRG1	stimulator of chondrogenesis 1	0.025
TGFBR3	transforming growth factor, beta receptor III	0.025
DOCK9	dedicator of cytokinesis 9	0.025
RARB	retinoic acid receptor, beta	0.025
CHD4	chromodomain helicase DNA binding protein 4	0.025
GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	0.025
TPM1	tropomyosin 1 (alpha)	0.025
JAG2	jagged 2	0.025
NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	0.025
ROR2	receptor tyrosine kinase-like orphan receptor 2	0.025
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.025
LRRC32	leucine rich repeat containing 32	0.025
ONECUT1	one cut homeobox 1	0.025
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.025
EZR	ezrin	0.025
NR2F2	nuclear receptor subfamily 2, group F, member 2	0.024	Human
HIC1	hypermethylated in cancer 1	0.024
GDNF	glial cell derived neurotrophic factor	0.024
NDUFB10	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa	0.024
PRR13	proline rich 13	0.024
PRNP	prion protein	0.024
WNT10B	wingless-type MMTV integration site family, member 10B	0.024	Human
CTGF	connective tissue growth factor	0.024
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.024
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.024
HTRA1	HtrA serine peptidase 1	0.024
ZFX	zinc finger protein, X-linked	0.024
PMEPA1	prostate transmembrane protein, androgen induced 1	0.024
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.024
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.024
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.024
BRD3	bromodomain containing 3	0.024
SALL3	sal-like 3 (Drosophila)	0.024
FBXL7	F-box and leucine-rich repeat protein 7	0.024
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.024
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.024
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.024
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.024
BTG2	BTG family, member 2	0.024
MED28	mediator complex subunit 28	0.024
BNC2	basonuclin 2	0.024
FZD9	frizzled homolog 9 (Drosophila)	0.024	Human
FOXE1	forkhead box E1 (thyroid transcription factor 2)	0.023
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.023
GATAD2B	GATA zinc finger domain containing 2B	0.023
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.023
TFPI2	tissue factor pathway inhibitor 2	0.023
COL13A1	collagen, type XIII, alpha 1	0.023
TCF4	transcription factor 4	0.023
NDUFA11	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa	0.023
TXNIP	thioredoxin interacting protein	0.023
PLAGL1	pleiomorphic adenoma gene-like 1	0.023
SCRT1	scratch homolog 1, zinc finger protein (Drosophila)	0.023
DACH1	dachshund homolog 1 (Drosophila)	0.023
GDF6	growth differentiation factor 6	0.023	Human
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.023
SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain	0.023
NDUFB11	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa	0.023
GPR161	G protein-coupled receptor 161	0.023
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.023
FZD10	frizzled homolog 10 (Drosophila)	0.023	Human
APLP1	amyloid beta (A4) precursor-like protein 1	0.023
SLC22A2	solute carrier family 22 (organic cation transporter), member 2	0.023
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.023
NOG	noggin	0.023
FGFR2	fibroblast growth factor receptor 2	0.023	Fly
CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma	0.023
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.023
TNC	tenascin C	0.022	Zebrafish
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.022
COL16A1	collagen, type XVI, alpha 1	0.022
DRD4	dopamine receptor D4	0.022
ACVR2A	activin A receptor, type IIA	0.022
ARHGAP5	Rho GTPase activating protein 5	0.022
HRC	histidine rich calcium binding protein	0.022
STAG1	stromal antigen 1	0.022
DEDD	death effector domain containing	0.022
FOXD3	forkhead box D3	0.022
PTK2	PTK2 protein tyrosine kinase 2	0.022
AMPH	amphiphysin	0.022
ARPC3	actin related protein 2/3 complex, subunit 3, 21kDa	0.022
PAX6	paired box 6	0.022
COL1A2	collagen, type I, alpha 2	0.022
SH3RF3	SH3 domain containing ring finger 3	0.022
MAPK8	mitogen-activated protein kinase 8	0.022
ZNF32	zinc finger protein 32	0.022
SERPINI2	serpin peptidase inhibitor, clade I (pancpin), member 2	0.022
USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	0.022
SOD3	superoxide dismutase 3, extracellular	0.022
EN2	engrailed homeobox 2	0.022
ARL4C	ADP-ribosylation factor-like 4C	0.022
SKP2	S-phase kinase-associated protein 2 (p45)	0.022
RNF31	ring finger protein 31	0.022
ROR1	receptor tyrosine kinase-like orphan receptor 1	0.022
DUSP2	dual specificity phosphatase 2	0.022
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.022
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.022
FOXA1	forkhead box A1	0.022	Fly
TRIM39	tripartite motif containing 39	0.022
CSNK1E	casein kinase 1, epsilon	0.022
CALCA	calcitonin-related polypeptide alpha	0.022
MYO6	myosin VI	0.022
FRZB	frizzled-related protein	0.022
BNC1	basonuclin 1	0.022
HOXD10	homeobox D10	0.022
NPHP1	nephronophthisis 1 (juvenile)	0.022
ADAMTS8	ADAM metallopeptidase with thrombospondin type 1 motif, 8	0.022
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.022
NKX3-1	NK3 homeobox 1	0.022
CDHR5	cadherin-related family member 5	0.022
DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1	0.022
POU3F3	POU class 3 homeobox 3	0.022
CHRD	chordin	0.021
RBX1	ring-box 1, E3 ubiquitin protein ligase	0.021
PPIA	peptidylprolyl isomerase A (cyclophilin A)	0.021
ENPP5	ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)	0.021
CYP11A1	cytochrome P450, family 11, subfamily A, polypeptide 1	0.021	Human
PKP1	plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)	0.021
EED	embryonic ectoderm development	0.021
THBS2	thrombospondin 2	0.021
SHOX2	short stature homeobox 2	0.021
ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)	0.021
KPNA4	karyopherin alpha 4 (importin alpha 3)	0.021
MGP	matrix Gla protein	0.021
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.021
AQP5	aquaporin 5	0.021
ZIC3	Zic family member 3 (odd-paired homolog, Drosophila)	0.021
PPP1R12C	protein phosphatase 1, regulatory (inhibitor) subunit 12C	0.021
LEF1	lymphoid enhancer-binding factor 1	0.021
FGD1	FYVE, RhoGEF and PH domain containing 1	0.021
NXPH4	neurexophilin 4	0.021
AMOT	angiomotin	0.021
GKAP1	G kinase anchoring protein 1	0.021
GATA5	GATA binding protein 5	0.021
RASSF9	Ras association (RalGDS/AF-6) domain family (N-terminal) member 9	0.021
SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)	0.021
GAB1	GRB2-associated binding protein 1	0.021
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.021
MNX1	motor neuron and pancreas homeobox 1	0.021
WNT5B	wingless-type MMTV integration site family, member 5B	0.021	Human
COL6A1	collagen, type VI, alpha 1	0.021
PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	0.021
S1PR5	sphingosine-1-phosphate receptor 5	0.021
EPHA3	EPH receptor A3	0.021
FRMD5	FERM domain containing 5	0.021
KPNA3	karyopherin alpha 3 (importin alpha 4)	0.021
GABARAPL1	GABA(A) receptor-associated protein like 1	0.021
BDKRB2	bradykinin receptor B2	0.021
FGF4	fibroblast growth factor 4	0.021
EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	0.021
CTTN	cortactin	0.021
IL11	interleukin 11	0.021
DNAJB6	DnaJ (Hsp40) homolog, subfamily B, member 6	0.021	Human
NCAN	neurocan	0.021
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.021	Fly
MYH9	myosin, heavy chain 9, non-muscle	0.021
DIXDC1	DIX domain containing 1	0.021
ITGB4	integrin, beta 4	0.021
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.021
HIPK3	homeodomain interacting protein kinase 3	0.021
DCBLD2	discoidin, CUB and LCCL domain containing 2	0.020
SLC6A8	solute carrier family 6 (neurotransmitter transporter, creatine), member 8	0.020
SIX3	SIX homeobox 3	0.020
SEPT4	septin 4	0.020
NPPC	natriuretic peptide C	0.020
KLF10	Kruppel-like factor 10	0.020
ATF7IP	activating transcription factor 7 interacting protein	0.020
RAB21	RAB21, member RAS oncogene family	0.020
QARS	glutaminyl-tRNA synthetase	0.020
IHH	Indian hedgehog	0.020
NDUFA9	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa	0.020
SFRP2	secreted frizzled-related protein 2	0.020
CRYAA	crystallin, alpha A	0.020
EDA	ectodysplasin A	0.020
EFNB2	ephrin-B2	0.020
CREB1	cAMP responsive element binding protein 1	0.020
CDH3	cadherin 3, type 1, P-cadherin (placental)	0.020
PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A	0.020
WNT3	wingless-type MMTV integration site family, member 3	0.020	Human
ZMIZ1	zinc finger, MIZ-type containing 1	0.020
HGFAC	HGF activator	0.020
FGB	fibrinogen beta chain	0.020
PHF12	PHD finger protein 12	0.020
USP42	ubiquitin specific peptidase 42	0.020
ARNT	aryl hydrocarbon receptor nuclear translocator	0.020
HNF1B	HNF1 homeobox B	0.020
DNAJC3	DnaJ (Hsp40) homolog, subfamily C, member 3	0.020
PRPH	peripherin	0.020
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.020
DAPK1	death-associated protein kinase 1	0.020
HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1	0.020
CALD1	caldesmon 1	0.020
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.020
LTBP1	latent transforming growth factor beta binding protein 1	0.020
GSC	goosecoid homeobox	0.020
PCDH8	protocadherin 8	0.020
TSSK2	testis-specific serine kinase 2	0.020
NEUROG2	neurogenin 2	0.020
MEF2C	myocyte enhancer factor 2C	0.020
LHX5	LIM homeobox 5	0.020
TBX3	T-box 3	0.020
DLX2	distal-less homeobox 2	0.020
RASL11B	RAS-like, family 11, member B	0.020	Human
EGFL7	EGF-like-domain, multiple 7	0.020
USH1C	Usher syndrome 1C (autosomal recessive, severe)	0.020
CSF1	colony stimulating factor 1 (macrophage)	0.020
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.020
HTRA3	HtrA serine peptidase 3	0.020
NFIB	nuclear factor I/B	0.019
EPHB3	EPH receptor B3	0.019
VGF	VGF nerve growth factor inducible	0.019
GNB3	guanine nucleotide binding protein (G protein), beta polypeptide 3	0.019
ANKRD44	ankyrin repeat domain 44	0.019
FGF19	fibroblast growth factor 19	0.019
NGF	nerve growth factor (beta polypeptide)	0.019
MN1	meningioma (disrupted in balanced translocation) 1	0.019
INSR	insulin receptor	0.019
ISL1	ISL LIM homeobox 1	0.019
UCP1	uncoupling protein 1 (mitochondrial, proton carrier)	0.019
NKD1	naked cuticle homolog 1 (Drosophila)	0.019
WT1	Wilms tumor 1	0.019
CDH4	cadherin 4, type 1, R-cadherin (retinal)	0.019
MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	0.019
CTPS2	CTP synthase II	0.019
MRPL34	mitochondrial ribosomal protein L34	0.019
BMP3	bone morphogenetic protein 3	0.019	Human
PRDM4	PR domain containing 4	0.019	Rat
MMP19	matrix metallopeptidase 19	0.019
CRLF1	cytokine receptor-like factor 1	0.019
BEST2	bestrophin 2	0.019
FEM1B	fem-1 homolog b (C. elegans)	0.019
GUCA2A	guanylate cyclase activator 2A (guanylin)	0.019
BAIAP2	BAI1-associated protein 2	0.019
GAPDHS	glyceraldehyde-3-phosphate dehydrogenase, spermatogenic	0.019
GPR4	G protein-coupled receptor 4	0.019
NES	nestin	0.019
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.019
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.019
ANTXR1	anthrax toxin receptor 1	0.019
PPP1R15B	protein phosphatase 1, regulatory (inhibitor) subunit 15B	0.019
HSPA1L	heat shock 70kDa protein 1-like	0.019	Human
HUNK	hormonally up-regulated Neu-associated kinase	0.019
THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)	0.019
ESRRB	estrogen-related receptor beta	0.019
VPRBP	Vpr (HIV-1) binding protein	0.019
RPS6KA5	ribosomal protein S6 kinase, 90kDa, polypeptide 5	0.019
PGM5	phosphoglucomutase 5	0.019
SNAI1	snail homolog 1 (Drosophila)	0.019
RASL12	RAS-like, family 12	0.019	Human
PSG9	pregnancy specific beta-1-glycoprotein 9	0.019
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.019
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.019
JUN	jun proto-oncogene	0.019
PIAS2	protein inhibitor of activated STAT, 2	0.019
SHH	sonic hedgehog	0.019
SEMA5A	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A	0.019	Rat
GAL	galanin prepropeptide	0.019
PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1	0.019
POU2F3	POU class 2 homeobox 3	0.019
KCNC3	potassium voltage-gated channel, Shaw-related subfamily, member 3	0.019
GALR2	galanin receptor 2	0.019
PTGES	prostaglandin E synthase	0.019
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.019
CCNE1	cyclin E1	0.019
PTF1A	pancreas specific transcription factor, 1a	0.019
PARVA	parvin, alpha	0.019
PPP1R1B	protein phosphatase 1, regulatory (inhibitor) subunit 1B	0.019
PAX7	paired box 7	0.019
USP46	ubiquitin specific peptidase 46	0.019
KDM5D	lysine (K)-specific demethylase 5D	0.019
DMPK	dystrophia myotonica-protein kinase	0.019
SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	0.019
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.019
SPRED1	sprouty-related, EVH1 domain containing 1	0.019
KDM1A	lysine (K)-specific demethylase 1A	0.019
ACRV1	acrosomal vesicle protein 1	0.018
SOX1	SRY (sex determining region Y)-box 1	0.018	Human
DAZAP2	DAZ associated protein 2	0.018
TSHZ3	teashirt zinc finger homeobox 3	0.018
TRIM32	tripartite motif containing 32	0.018
CDH2	cadherin 2, type 1, N-cadherin (neuronal)	0.018
SOX4	SRY (sex determining region Y)-box 4	0.018	Human
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.018
INHBA	inhibin, beta A	0.018
EPHB2	EPH receptor B2	0.018
DACT1	dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)	0.018
SIM2	single-minded homolog 2 (Drosophila)	0.018
MAP2	microtubule-associated protein 2	0.018
ASNA1	arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)	0.018
GPRC5B	G protein-coupled receptor, family C, group 5, member B	0.018
FBN2	fibrillin 2	0.018
IRX5	iroquois homeobox 5	0.018
WNT1	wingless-type MMTV integration site family, member 1	0.018	Human
GPC3	glypican 3	0.018
C10orf116	chromosome 10 open reading frame 116	0.018
EPHA4	EPH receptor A4	0.018
USH1G	Usher syndrome 1G (autosomal recessive)	0.018
MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	0.018
PTMS	parathymosin	0.018
UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked	0.018
PPP1R10	protein phosphatase 1, regulatory (inhibitor) subunit 10	0.018
RGS16	regulator of G-protein signaling 16	0.018
RPL3L	ribosomal protein L3-like	0.018