IMP: Integrative Multi-species Prediction

Homo sapiens

183 genes annotated in human

Multi-species View

negative regulation of intracellular signal transduction

GO:1902532

Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "negative regulation of intracellular signal transduction"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "negative regulation of intracellular signal transduction" (in gray)

Name	Description	Probability	Func Analog Organism
PTPN1	protein tyrosine phosphatase, non-receptor type 1	0.998	Human Yeast Mouse
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.995
UBC	ubiquitin C	0.992
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	0.991
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	0.989
RELA	v-rel reticuloendotheliosis viral oncogene homolog A (avian)	0.973
MAP3K7	mitogen-activated protein kinase kinase kinase 7	0.970
FYN	FYN oncogene related to SRC, FGR, YES	0.966	Human
MAPK14	mitogen-activated protein kinase 14	0.952
ESR1	estrogen receptor 1	0.943
MAPK1	mitogen-activated protein kinase 1	0.938	Yeast
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.907	Human
GRB2	growth factor receptor-bound protein 2	0.895	Human
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.891
TP53	tumor protein p53	0.876
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	0.875	Human
PDCD6IP	programmed cell death 6 interacting protein	0.873
EGFR	epidermal growth factor receptor	0.857
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.854	Mouse Worm
HDAC1	histone deacetylase 1	0.846	Mouse Worm
BCL2	B-cell CLL/lymphoma 2	0.824
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	0.806
NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	0.771
GHR	growth hormone receptor	0.761
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.755
YAP1	Yes-associated protein 1	0.737
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.735
IKBKB	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta	0.718
MAPK8	mitogen-activated protein kinase 8	0.707	Fly
SH3KBP1	SH3-domain kinase binding protein 1	0.694
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.693
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.683
LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)	0.649
ZNF43	zinc finger protein 43	0.618
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	0.607	Mouse
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.599
BTRC	beta-transducin repeat containing	0.583	Fly
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.557
PRKCZ	protein kinase C, zeta	0.552	Human
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.542
GSK3B	glycogen synthase kinase 3 beta	0.506	Rat Fly
FBXW11	F-box and WD repeat domain containing 11	0.502	Mouse Fly
BMI1	BMI1 polycomb ring finger oncogene	0.498
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.498
CFLAR	CASP8 and FADD-like apoptosis regulator	0.494
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.479	Human
IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma	0.465	Mouse
SQSTM1	sequestosome 1	0.463
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.461
MPDZ	multiple PDZ domain protein	0.442
JUN	jun proto-oncogene	0.433
PML	promyelocytic leukemia	0.422
FAS	Fas (TNF receptor superfamily, member 6)	0.420
CRK	v-crk sarcoma virus CT10 oncogene homolog (avian)	0.412
CREBBP	CREB binding protein	0.412
DUSP1	dual specificity phosphatase 1	0.402
FHL2	four and a half LIM domains 2	0.400
TRAF6	TNF receptor-associated factor 6	0.387
TSC2	tuberous sclerosis 2	0.384	Mouse Rat Fly
KEAP1	kelch-like ECH-associated protein 1	0.383
BIRC2	baculoviral IAP repeat containing 2	0.380
CHUK	conserved helix-loop-helix ubiquitous kinase	0.371	Zebrafish
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.364	Fly
RNF11	ring finger protein 11	0.352
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.349	Human
MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	0.344
PTK2	PTK2 protein tyrosine kinase 2	0.332	Fly
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.329
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.329
BCAR1	breast cancer anti-estrogen resistance 1	0.325
RICTOR	RPTOR independent companion of MTOR, complex 2	0.322
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.318
INSR	insulin receptor	0.314	Human
MYD88	myeloid differentiation primary response gene (88)	0.304
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.302
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.300
ZNF746	zinc finger protein 746	0.297
PTEN	phosphatase and tensin homolog	0.294
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.290
GUCY2C	guanylate cyclase 2C (heat stable enterotoxin receptor)	0.288
SMAD3	SMAD family member 3	0.281
ZNF253	zinc finger protein 253	0.279
SYK	spleen tyrosine kinase	0.278
BMPR1A	bone morphogenetic protein receptor, type IA	0.277
CFTR	cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)	0.277
ZNF273	zinc finger protein 273	0.271	Human
OPTN	optineurin	0.264
LCK	lymphocyte-specific protein tyrosine kinase	0.263	Human
MAP2K4	mitogen-activated protein kinase kinase 4	0.262
VCP	valosin containing protein	0.262
MAPKAPK2	mitogen-activated protein kinase-activated protein kinase 2	0.259
BCL2L1	BCL2-like 1	0.259
NCOR2	nuclear receptor corepressor 2	0.258	Human
CBX5	chromobox homolog 5	0.255	Worm
MED28	mediator complex subunit 28	0.254
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.253
MAP2K3	mitogen-activated protein kinase kinase 3	0.253
NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1	0.253
UBE2B	ubiquitin-conjugating enzyme E2B (RAD6 homolog)	0.251
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.250
SPRR2A	small proline-rich protein 2A	0.244
ADNP	activity-dependent neuroprotector homeobox	0.238
NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta	0.237
BAG3	BCL2-associated athanogene 3	0.236
CCNE1	cyclin E1	0.233
MAP2K1	mitogen-activated protein kinase kinase 1	0.231
RB1	retinoblastoma 1	0.229
NCOA1	nuclear receptor coactivator 1	0.227
NLRC4	NLR family, CARD domain containing 4	0.223
KDM1A	lysine (K)-specific demethylase 1A	0.222
PSEN2	presenilin 2 (Alzheimer disease 4)	0.222
STAT1	signal transducer and activator of transcription 1, 91kDa	0.221
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.221
XIAP	X-linked inhibitor of apoptosis	0.221
REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	0.217
GRB10	growth factor receptor-bound protein 10	0.215
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.215	Human
CSNK2B	casein kinase 2, beta polypeptide	0.214
RASA1	RAS p21 protein activator (GTPase activating protein) 1	0.213
CSNK2A1	casein kinase 2, alpha 1 polypeptide	0.213
CAV1	caveolin 1, caveolae protein, 22kDa	0.212	Mouse
RUNX1	runt-related transcription factor 1	0.212
BIRC3	baculoviral IAP repeat containing 3	0.211
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.210
BCL3	B-cell CLL/lymphoma 3	0.209	Human
MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	0.208
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.207
MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)	0.205
RAC1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	0.204
PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	0.204
SCRIB	scribbled homolog (Drosophila)	0.203
ZNF675	zinc finger protein 675	0.203
TNFAIP1	tumor necrosis factor, alpha-induced protein 1 (endothelial)	0.202
ATF2	activating transcription factor 2	0.202
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.202
ATF3	activating transcription factor 3	0.200
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.199
RIPK1	receptor (TNFRSF)-interacting serine-threonine kinase 1	0.199
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.195	Worm
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.193	Mouse
VAV1	vav 1 guanine nucleotide exchange factor	0.192
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.190
FADD	Fas (TNFRSF6)-associated via death domain	0.189
SPRY2	sprouty homolog 2 (Drosophila)	0.186	Mouse
PXN	paxillin	0.186
LAT	linker for activation of T cells	0.183
SOCS3	suppressor of cytokine signaling 3	0.183
SFPQ	splicing factor proline/glutamine-rich	0.181	Human
UBASH3B	ubiquitin associated and SH3 domain containing B	0.181
HSPA4	heat shock 70kDa protein 4	0.180
BID	BH3 interacting domain death agonist	0.179
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.178
FN1	fibronectin 1	0.177
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.177	Mouse
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.174
DAPK1	death-associated protein kinase 1	0.173
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.173
NCAM1	neural cell adhesion molecule 1	0.170
RIPK2	receptor-interacting serine-threonine kinase 2	0.169	Human
MAP3K8	mitogen-activated protein kinase kinase kinase 8	0.168
NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta	0.167	Human Rat
VIM	vimentin	0.167
PPP1CC	protein phosphatase 1, catalytic subunit, gamma isozyme	0.166
PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma	0.165
RYBP	RING1 and YY1 binding protein	0.165
MAPK6	mitogen-activated protein kinase 6	0.164
UBE2V1	ubiquitin-conjugating enzyme E2 variant 1	0.163
NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like	0.162
SETD7	SET domain containing (lysine methyltransferase) 7	0.161
HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	0.161
PEA15	phosphoprotein enriched in astrocytes 15	0.161
MSN	moesin	0.160	Human
CD2AP	CD2-associated protein	0.159
ZNF91	zinc finger protein 91	0.159
CYLD	cylindromatosis (turban tumor syndrome)	0.158
BAD	BCL2-associated agonist of cell death	0.158
IRAK2	interleukin-1 receptor-associated kinase 2	0.157	Human
TNFRSF1A	tumor necrosis factor receptor superfamily, member 1A	0.157
BCR	breakpoint cluster region	0.157
EPOR	erythropoietin receptor	0.157
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.157
NR0B1	nuclear receptor subfamily 0, group B, member 1	0.156
SC4MOL	sterol-C4-methyl oxidase-like	0.156
MYH9	myosin, heavy chain 9, non-muscle	0.156
RHOA	ras homolog gene family, member A	0.155
SIN3A	SIN3 homolog A, transcription regulator (yeast)	0.155
ZHX1	zinc fingers and homeoboxes 1	0.155
LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)	0.154
TGFB1	transforming growth factor, beta 1	0.153
AR	androgen receptor	0.152
NCOA3	nuclear receptor coactivator 3	0.151
NR1H2	nuclear receptor subfamily 1, group H, member 2	0.151
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.150
MAP3K14	mitogen-activated protein kinase kinase kinase 14	0.146
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.145
WEE1	WEE1 homolog (S. pombe)	0.145
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	0.143	Fly
NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon	0.143	Human
ZNF85	zinc finger protein 85	0.143	Human
BLNK	B-cell linker	0.142
KAT2B	K(lysine) acetyltransferase 2B	0.141
FOXD3	forkhead box D3	0.141
MAP2K5	mitogen-activated protein kinase kinase 5	0.140
CUL1	cullin 1	0.139	Fly
BMPR2	bone morphogenetic protein receptor, type II (serine/threonine kinase)	0.139
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.138
AHR	aryl hydrocarbon receptor	0.138
CD44	CD44 molecule (Indian blood group)	0.138
SNAI1	snail homolog 1 (Drosophila)	0.138
BBS10	Bardet-Biedl syndrome 10	0.138
TRIM28	tripartite motif containing 28	0.137
GOPC	golgi-associated PDZ and coiled-coil motif containing	0.136
PRKCB	protein kinase C, beta	0.136
HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	0.136
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.134
MAVS	mitochondrial antiviral signaling protein	0.134
IGF1R	insulin-like growth factor 1 receptor	0.131
LNX1	ligand of numb-protein X 1	0.131
SOCS1	suppressor of cytokine signaling 1	0.131	Zebrafish Mouse
PPP1CA	protein phosphatase 1, catalytic subunit, alpha isozyme	0.130
ZNF117	zinc finger protein 117	0.130	Human
EZR	ezrin	0.128	Human
IQGAP1	IQ motif containing GTPase activating protein 1	0.128
APAF1	apoptotic peptidase activating factor 1	0.128
CUL2	cullin 2	0.128
TICAM2	toll-like receptor adaptor molecule 2	0.128
ICAM1	intercellular adhesion molecule 1	0.126
PARK2	parkinson protein 2, E3 ubiquitin protein ligase (parkin)	0.125
WWP2	WW domain containing E3 ubiquitin protein ligase 2	0.125
PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)	0.125
ZNF260	zinc finger protein 260	0.124
STAMBP	STAM binding protein	0.124
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.124	Human
IRF1	interferon regulatory factor 1	0.122
TSC1	tuberous sclerosis 1	0.122
FLNA	filamin A, alpha	0.121
E2F4	E2F transcription factor 4, p107/p130-binding	0.120
MBP	myelin basic protein	0.120
KLF6	Kruppel-like factor 6	0.120
ADRB1	adrenergic, beta-1-, receptor	0.120
BAX	BCL2-associated X protein	0.118	Human
SCHIP1	schwannomin interacting protein 1	0.118
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.117
ZNF93	zinc finger protein 93	0.116
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.116
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.116
CDK2	cyclin-dependent kinase 2	0.115
EEF2K	eukaryotic elongation factor-2 kinase	0.115
KIF1B	kinesin family member 1B	0.114
C1QA	complement component 1, q subcomponent, A chain	0.114	Human
MTOR	mechanistic target of rapamycin (serine/threonine kinase)	0.113
HCK	hemopoietic cell kinase	0.112	Human
VHL	von Hippel-Lindau tumor suppressor	0.112
ITK	IL2-inducible T-cell kinase	0.112
CASP9	caspase 9, apoptosis-related cysteine peptidase	0.111	Human
TNIP2	TNFAIP3 interacting protein 2	0.111
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.111
IL4R	interleukin 4 receptor	0.111
USP46	ubiquitin specific peptidase 46	0.111
SH3GL2	SH3-domain GRB2-like 2	0.111
IL1R1	interleukin 1 receptor, type I	0.110
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.109
CDK6	cyclin-dependent kinase 6	0.109
IRS2	insulin receptor substrate 2	0.108
UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	0.108	Human
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.108
LAMP1	lysosomal-associated membrane protein 1	0.107
ZNF254	zinc finger protein 254	0.107	Human
C1QC	complement component 1, q subcomponent, C chain	0.107	Human
FASLG	Fas ligand (TNF superfamily, member 6)	0.106	Human
HGS	hepatocyte growth factor-regulated tyrosine kinase substrate	0.105
DDX58	DEAD (Asp-Glu-Ala-Asp) box polypeptide 58	0.105	Human
RAB21	RAB21, member RAS oncogene family	0.104
ARRB1	arrestin, beta 1	0.104
SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	0.103
MAP2K7	mitogen-activated protein kinase kinase 7	0.103
HDAC6	histone deacetylase 6	0.103
CSK	c-src tyrosine kinase	0.103	Rat
ARRB2	arrestin, beta 2	0.103
DUSP6	dual specificity phosphatase 6	0.102
MARCH5	membrane-associated ring finger (C3HC4) 5	0.102
TSC22D1	TSC22 domain family, member 1	0.102
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.101
RCHY1	ring finger and CHY zinc finger domain containing 1	0.100
ZFP36L1	zinc finger protein 36, C3H type-like 1	0.100
STRN4	striatin, calmodulin binding protein 4	0.100
CSNK1E	casein kinase 1, epsilon	0.099
FBXO7	F-box protein 7	0.099
GBP3	guanylate binding protein 3	0.099
RAB6A	RAB6A, member RAS oncogene family	0.099
HIPK3	homeodomain interacting protein kinase 3	0.099	Mouse
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.099
KLHL3	kelch-like 3 (Drosophila)	0.098
ILK	integrin-linked kinase	0.098
INPP5D	inositol polyphosphate-5-phosphatase, 145kDa	0.098
ZNF430	zinc finger protein 430	0.097	Human
RALB	v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)	0.097	Fly
RABGAP1	RAB GTPase activating protein 1	0.097
PTPN7	protein tyrosine phosphatase, non-receptor type 7	0.097	Human Fly
SOCS2	suppressor of cytokine signaling 2	0.096	Mouse
LASS2	LAG1 homolog, ceramide synthase 2	0.096
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.095
APPBP2	amyloid beta precursor protein (cytoplasmic tail) binding protein 2	0.095
DUSP7	dual specificity phosphatase 7	0.095
RIN1	Ras and Rab interactor 1	0.094
EGR2	early growth response 2	0.094
MAPK3	mitogen-activated protein kinase 3	0.094	Yeast
IRF3	interferon regulatory factor 3	0.094
HTRA2	HtrA serine peptidase 2	0.094
DUSP3	dual specificity phosphatase 3	0.094
PTPRB	protein tyrosine phosphatase, receptor type, B	0.093	Human
YBX1	Y box binding protein 1	0.093	Human
TLN1	talin 1	0.093
SH3RF1	SH3 domain containing ring finger 1	0.093
PLCG1	phospholipase C, gamma 1	0.093
VDR	vitamin D (1,25- dihydroxyvitamin D3) receptor	0.092
WFIKKN2	WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2	0.091
RIPK3	receptor-interacting serine-threonine kinase 3	0.091	Human
DERL1	Der1-like domain family, member 1	0.090
EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	0.090
LIMD1	LIM domains containing 1	0.088
PPARA	peroxisome proliferator-activated receptor alpha	0.088
CCND1	cyclin D1	0.088
STAM2	signal transducing adaptor molecule (SH3 domain and ITAM motif) 2	0.088
ZNF84	zinc finger protein 84	0.088
LMO2	LIM domain only 2 (rhombotin-like 1)	0.088	Human
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.088
HSPA8	heat shock 70kDa protein 8	0.087
TRIM33	tripartite motif containing 33	0.086
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.085	Human
CDCP1	CUB domain containing protein 1	0.085
SETD8	SET domain containing (lysine methyltransferase) 8	0.085
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.085
ADRB2	adrenergic, beta-2-, receptor, surface	0.085
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.085
HTT	huntingtin	0.084
TP53BP2	tumor protein p53 binding protein, 2	0.084
ATXN3	ataxin 3	0.083
GFM1	G elongation factor, mitochondrial 1	0.083
PTPN11	protein tyrosine phosphatase, non-receptor type 11	0.083
CLOCK	clock homolog (mouse)	0.083
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.083
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.083
NUP54	nucleoporin 54kDa	0.083
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.083
SKP2	S-phase kinase-associated protein 2 (p45)	0.083
PYCARD	PYD and CARD domain containing	0.082
BMPR1B	bone morphogenetic protein receptor, type IB	0.082
MTA2	metastasis associated 1 family, member 2	0.082
BCL2L11	BCL2-like 11 (apoptosis facilitator)	0.081
RPTOR	regulatory associated protein of MTOR, complex 1	0.081
ZCCHC17	zinc finger, CCHC domain containing 17	0.081
CCL3	chemokine (C-C motif) ligand 3	0.080
ZC3H12A	zinc finger CCCH-type containing 12A	0.080
ARHGDIA	Rho GDP dissociation inhibitor (GDI) alpha	0.080
ADAM15	ADAM metallopeptidase domain 15	0.080
EIF2C1	eukaryotic translation initiation factor 2C, 1	0.080
NCK1	NCK adaptor protein 1	0.079
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.079	Human
FOXO1	forkhead box O1	0.079
SIRT6	sirtuin 6	0.079
CTBP1	C-terminal binding protein 1	0.078
GRB7	growth factor receptor-bound protein 7	0.078
CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1	0.078
PPARG	peroxisome proliferator-activated receptor gamma	0.078
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.078
DOCK7	dedicator of cytokinesis 7	0.078
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.078
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.078
PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)	0.077
FOSB	FBJ murine osteosarcoma viral oncogene homolog B	0.077
FOS	FBJ murine osteosarcoma viral oncogene homolog	0.077
ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	0.077	Mouse Worm
ARHGAP9	Rho GTPase activating protein 9	0.077
FLNB	filamin B, beta	0.076
EFNA5	ephrin-A5	0.075
DDAH2	dimethylarginine dimethylaminohydrolase 2	0.075
TRPC4	transient receptor potential cation channel, subfamily C, member 4	0.075
IRF9	interferon regulatory factor 9	0.074
IRAK1	interleukin-1 receptor-associated kinase 1	0.074	Human
EFTUD2	elongation factor Tu GTP binding domain containing 2	0.074
ZNF71	zinc finger protein 71	0.073
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.073
TSG101	tumor susceptibility gene 101	0.073
PLK3	polo-like kinase 3	0.073
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.072
SKP1	S-phase kinase-associated protein 1	0.072	Fly
SOS1	son of sevenless homolog 1 (Drosophila)	0.072
EP300	E1A binding protein p300	0.072
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.072
TBC1D10A	TBC1 domain family, member 10A	0.071
FYB	FYN binding protein	0.071
E2F3	E2F transcription factor 3	0.071
NOG	noggin	0.071
HDAC5	histone deacetylase 5	0.071
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.071
PBK	PDZ binding kinase	0.070	Mouse
LDB1	LIM domain binding 1	0.070
CRTC2	CREB regulated transcription coactivator 2	0.070
PNPLA2	patatin-like phospholipase domain containing 2	0.070
ACACA	acetyl-CoA carboxylase alpha	0.070
HP	haptoglobin	0.070
TFF1	trefoil factor 1	0.069
ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	0.069
CACNA1C	calcium channel, voltage-dependent, L type, alpha 1C subunit	0.069
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.069
MAGEA2	melanoma antigen family A, 2	0.069
FOXO3	forkhead box O3	0.069	Human
TESK1	testis-specific kinase 1	0.069
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.069
RHOB	ras homolog gene family, member B	0.069
NOXA1	NADPH oxidase activator 1	0.068
DNMT1	DNA (cytosine-5-)-methyltransferase 1	0.068
RAB10	RAB10, member RAS oncogene family	0.068
UBE3A	ubiquitin protein ligase E3A	0.068
CUL3	cullin 3	0.068
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.067
IL8	interleukin 8	0.067
ELF4	E74-like factor 4 (ets domain transcription factor)	0.067
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.067	Human
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.067
JAK2	Janus kinase 2	0.067
CDK1	cyclin-dependent kinase 1	0.067
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.067
DUSP5	dual specificity phosphatase 5	0.066	Human Rat
APOC1	apolipoprotein C-I	0.066
PDCD10	programmed cell death 10	0.066
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.066
TRIM63	tripartite motif containing 63	0.066	Human
CRADD	CASP2 and RIPK1 domain containing adaptor with death domain	0.066
TOLLIP	toll interacting protein	0.066
ZNF708	zinc finger protein 708	0.066	Human
TAL1	T-cell acute lymphocytic leukemia 1	0.066	Human
DLG1	discs, large homolog 1 (Drosophila)	0.065	Mouse
CXCR4	chemokine (C-X-C motif) receptor 4	0.065
TUBB2B	tubulin, beta 2B	0.065
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.065	Human
RPS6KA1	ribosomal protein S6 kinase, 90kDa, polypeptide 1	0.065	Fly
NCF1	neutrophil cytosolic factor 1	0.065
ARL4D	ADP-ribosylation factor-like 4D	0.064
RXRA	retinoid X receptor, alpha	0.064
MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)	0.064
AXIN1	axin 1	0.064
SMAD2	SMAD family member 2	0.064
E2F6	E2F transcription factor 6	0.064
SIRT1	sirtuin 1	0.064
RHOG	ras homolog gene family, member G (rho G)	0.064
HSF1	heat shock transcription factor 1	0.064	Yeast
MYO1C	myosin IC	0.063
RABEP1	rabaptin, RAB GTPase binding effector protein 1	0.063
SFN	stratifin	0.063
SLC9A3R2	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2	0.063	Human Mouse
JAK3	Janus kinase 3	0.063
TRIM37	tripartite motif containing 37	0.063
MBD3	methyl-CpG binding domain protein 3	0.063
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.062
ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A	0.062
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.062
RAI1	retinoic acid induced 1	0.062
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.062
PKM2	pyruvate kinase, muscle	0.061
WBP2	WW domain binding protein 2	0.061
CUX1	cut-like homeobox 1	0.061
NPTN	neuroplastin	0.061
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.061
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.061
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.061
AMFR	autocrine motility factor receptor	0.061
ROCK2	Rho-associated, coiled-coil containing protein kinase 2	0.061
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.061
ZC3HAV1	zinc finger CCCH-type, antiviral 1	0.060
USP15	ubiquitin specific peptidase 15	0.060
APP	amyloid beta (A4) precursor protein	0.060
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.060
DDR2	discoidin domain receptor tyrosine kinase 2	0.060
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.060
HIVEP2	human immunodeficiency virus type I enhancer binding protein 2	0.060
TSC22D3	TSC22 domain family, member 3	0.060
FAM134A	family with sequence similarity 134, member A	0.060
ADORA2A	adenosine A2a receptor	0.059
EFNA1	ephrin-A1	0.059
APLP2	amyloid beta (A4) precursor-like protein 2	0.059
CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	0.058
ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)	0.058
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.058
VCL	vinculin	0.058
GOLGA2	golgin A2	0.058
MAPT	microtubule-associated protein tau	0.058
CDH1	cadherin 1, type 1, E-cadherin (epithelial)	0.058
POGZ	pogo transposable element with ZNF domain	0.058
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.057
IKBKE	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon	0.057
HLA-B	major histocompatibility complex, class I, B	0.056
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.056
NFE2L2	nuclear factor (erythroid-derived 2)-like 2	0.056
RPRD1A	regulation of nuclear pre-mRNA domain containing 1A	0.056
HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	0.056
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.056
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.056	Human
RAPGEF2	Rap guanine nucleotide exchange factor (GEF) 2	0.056
ZFAND5	zinc finger, AN1-type domain 5	0.056
CAPRIN1	cell cycle associated protein 1	0.056
PTPRR	protein tyrosine phosphatase, receptor type, R	0.056
SENP3	SUMO1/sentrin/SMT3 specific peptidase 3	0.056
ANLN	anillin, actin binding protein	0.056
RAB11FIP2	RAB11 family interacting protein 2 (class I)	0.055
HSPA1L	heat shock 70kDa protein 1-like	0.055
KCTD10	potassium channel tetramerisation domain containing 10	0.055	Human
PPP6C	protein phosphatase 6, catalytic subunit	0.055
ZNF107	zinc finger protein 107	0.055
USP9X	ubiquitin specific peptidase 9, X-linked	0.055
PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)	0.055	Mouse
IBTK	inhibitor of Bruton agammaglobulinemia tyrosine kinase	0.055
GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa	0.055
HES1	hairy and enhancer of split 1, (Drosophila)	0.055
UROD	uroporphyrinogen decarboxylase	0.055
DCAF7	DDB1 and CUL4 associated factor 7	0.055
HUWE1	HECT, UBA and WWE domain containing 1	0.055
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.054
HDAC3	histone deacetylase 3	0.054
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.054	Worm
AMOT	angiomotin	0.054
ANXA1	annexin A1	0.054
AMOTL1	angiomotin like 1	0.054
GATA2	GATA binding protein 2	0.054
ZNF680	zinc finger protein 680	0.054	Human
STAP2	signal transducing adaptor family member 2	0.054
MEFV	Mediterranean fever	0.054
NEDD9	neural precursor cell expressed, developmentally down-regulated 9	0.054
CISH	cytokine inducible SH2-containing protein	0.054
PARVA	parvin, alpha	0.054
DUSP16	dual specificity phosphatase 16	0.053	Human Mouse Worm
GBP5	guanylate binding protein 5	0.053
IL12RB2	interleukin 12 receptor, beta 2	0.053
TRIM25	tripartite motif containing 25	0.053
IER3	immediate early response 3	0.053
FHL3	four and a half LIM domains 3	0.053
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.053
IER2	immediate early response 2	0.053
TSEN15	tRNA splicing endonuclease 15 homolog (S. cerevisiae)	0.053
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.053
CCND3	cyclin D3	0.052
EFR3A	EFR3 homolog A (S. cerevisiae)	0.052
LIN28B	lin-28 homolog B (C. elegans)	0.052
EEF1A1	eukaryotic translation elongation factor 1 alpha 1	0.052
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.052
AKAP11	A kinase (PRKA) anchor protein 11	0.052
BAI1	brain-specific angiogenesis inhibitor 1	0.052
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.052
PTPN21	protein tyrosine phosphatase, non-receptor type 21	0.052	Fly
BAK1	BCL2-antagonist/killer 1	0.052	Human
PTPRA	protein tyrosine phosphatase, receptor type, A	0.052
NCK2	NCK adaptor protein 2	0.052
MUC1	mucin 1, cell surface associated	0.052
UBE2G1	ubiquitin-conjugating enzyme E2G 1 (UBC7 homolog, yeast)	0.052
ZNF45	zinc finger protein 45	0.052
SOX4	SRY (sex determining region Y)-box 4	0.052
NCKAP1	NCK-associated protein 1	0.052
EIF2AK2	eukaryotic translation initiation factor 2-alpha kinase 2	0.052
ITGA7	integrin, alpha 7	0.051
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.051
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.051
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.051
TIAM1	T-cell lymphoma invasion and metastasis 1	0.051
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.051
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.051
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.051
BHLHE40	basic helix-loop-helix family, member e40	0.051
CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	0.051
JAK1	Janus kinase 1	0.051
CTNND1	catenin (cadherin-associated protein), delta 1	0.051
DCN	decorin	0.051
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.051
KLC1	kinesin light chain 1	0.050
ITGB4	integrin, beta 4	0.050
C1orf144	chromosome 1 open reading frame 144	0.050
PSEN1	presenilin 1	0.050
CCKBR	cholecystokinin B receptor	0.050
MTA1	metastasis associated 1	0.050
PRKCQ	protein kinase C, theta	0.050	Human
TRAF4	TNF receptor-associated factor 4	0.050
VCAM1	vascular cell adhesion molecule 1	0.050
PPP4C	protein phosphatase 4, catalytic subunit	0.050
SMAD7	SMAD family member 7	0.050
KLF5	Kruppel-like factor 5 (intestinal)	0.050
INF2	inverted formin, FH2 and WH2 domain containing	0.050
SMPD1	sphingomyelin phosphodiesterase 1, acid lysosomal	0.050
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.050
SLK	STE20-like kinase	0.050
ZRANB1	zinc finger, RAN-binding domain containing 1	0.050	Human
SOCS5	suppressor of cytokine signaling 5	0.049	Fly
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.049
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.049
TMEM173	transmembrane protein 173	0.049
CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	0.049	Human
CAV2	caveolin 2	0.049
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.049
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.049
STK24	serine/threonine kinase 24	0.049	Worm
HNF1A	HNF1 homeobox A	0.049
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.049
SC5DL	sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like	0.049
PPAP2B	phosphatidic acid phosphatase type 2B	0.049
IGF2R	insulin-like growth factor 2 receptor	0.049
PHLDB2	pleckstrin homology-like domain, family B, member 2	0.049
CBX1	chromobox homolog 1	0.048	Worm
PTPN14	protein tyrosine phosphatase, non-receptor type 14	0.048	Fly
IRAK3	interleukin-1 receptor-associated kinase 3	0.048
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.048	Human
TGFB2	transforming growth factor, beta 2	0.048
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.048
XPO6	exportin 6	0.048
DST	dystonin	0.048
SORBS1	sorbin and SH3 domain containing 1	0.048
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.048
ZMYND19	zinc finger, MYND-type containing 19	0.048
DNAJB11	DnaJ (Hsp40) homolog, subfamily B, member 11	0.048
EIF1	eukaryotic translation initiation factor 1	0.048
SRCIN1	SRC kinase signaling inhibitor 1	0.048
EGR1	early growth response 1	0.048	Worm
DUSP4	dual specificity phosphatase 4	0.048	Human Rat
CSNK1D	casein kinase 1, delta	0.048
BTN3A1	butyrophilin, subfamily 3, member A1	0.047
SH3GL3	SH3-domain GRB2-like 3	0.047
MAP3K10	mitogen-activated protein kinase kinase kinase 10	0.047
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.047
SLC9A3	solute carrier family 9 (sodium/hydrogen exchanger), member 3	0.047
ZNF682	zinc finger protein 682	0.047	Human
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.047	Human
MYO10	myosin X	0.047
TCF21	transcription factor 21	0.047
PLEC	plectin	0.047
PCDH9	protocadherin 9	0.047
SPRED1	sprouty-related, EVH1 domain containing 1	0.047	Mouse
CSNK2A2	casein kinase 2, alpha prime polypeptide	0.047
RALBP1	ralA binding protein 1	0.047
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.047
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.047
FCHSD2	FCH and double SH3 domains 2	0.047
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.047
CXCL12	chemokine (C-X-C motif) ligand 12	0.047
PRKCE	protein kinase C, epsilon	0.047
DAD1	defender against cell death 1	0.047
LCAT	lecithin-cholesterol acyltransferase	0.047
ZFP36	zinc finger protein 36, C3H type, homolog (mouse)	0.047
BIRC6	baculoviral IAP repeat containing 6	0.046
PPP1R13B	protein phosphatase 1, regulatory (inhibitor) subunit 13B	0.046
ZNF432	zinc finger protein 432	0.046
GNS	glucosamine (N-acetyl)-6-sulfatase	0.046
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.046	Human
ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	0.046
TNFAIP6	tumor necrosis factor, alpha-induced protein 6	0.046	Human
GAB1	GRB2-associated binding protein 1	0.046
POU4F3	POU class 4 homeobox 3	0.046
ARNT	aryl hydrocarbon receptor nuclear translocator	0.046
ZNF420	zinc finger protein 420	0.046
UBE2N	ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)	0.046
GSN	gelsolin	0.046
DMD	dystrophin	0.046
USP7	ubiquitin specific peptidase 7 (herpes virus-associated)	0.046
JUNB	jun B proto-oncogene	0.046
TGFA	transforming growth factor, alpha	0.046
SRI	sorcin	0.045
TIMP3	TIMP metallopeptidase inhibitor 3	0.045
ERN1	endoplasmic reticulum to nucleus signaling 1	0.045
INADL	InaD-like (Drosophila)	0.045
MFAP5	microfibrillar associated protein 5	0.045
DSCAML1	Down syndrome cell adhesion molecule like 1	0.045
EMP1	epithelial membrane protein 1	0.045
FBLN1	fibulin 1	0.045
SPI1	spleen focus forming virus (SFFV) proviral integration oncogene spi1	0.045
CD14	CD14 molecule	0.045
UBASH3A	ubiquitin associated and SH3 domain containing A	0.045
HLA-DQB1	major histocompatibility complex, class II, DQ beta 1	0.045
BMP4	bone morphogenetic protein 4	0.045
TLR2	toll-like receptor 2	0.045
BTG2	BTG family, member 2	0.045
UBE2D1	ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)	0.045
DBN1	drebrin 1	0.045
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.045
TSC22D4	TSC22 domain family, member 4	0.045
SPTBN4	spectrin, beta, non-erythrocytic 4	0.045
ERBB2IP	erbb2 interacting protein	0.045
POLH	polymerase (DNA directed), eta	0.045
AMOTL2	angiomotin like 2	0.044
AHNAK	AHNAK nucleoprotein	0.044
H3F3A	H3 histone, family 3A	0.044
BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	0.044	Human
TPM4	tropomyosin 4	0.044
SPTBN1	spectrin, beta, non-erythrocytic 1	0.044
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.044
MAP2	microtubule-associated protein 2	0.044
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.044
EPHB2	EPH receptor B2	0.044	Human
OXSR1	oxidative-stress responsive 1	0.044
ADARB1	adenosine deaminase, RNA-specific, B1	0.044
DNM2	dynamin 2	0.044
BCL2A1	BCL2-related protein A1	0.044
CADM4	cell adhesion molecule 4	0.044
OGT	O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)	0.044
PROX1	prospero homeobox 1	0.044
GBP4	guanylate binding protein 4	0.044
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.044
MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)	0.044
CCL20	chemokine (C-C motif) ligand 20	0.044
C19orf50	chromosome 19 open reading frame 50	0.044
RAD18	RAD18 homolog (S. cerevisiae)	0.044
ILF2	interleukin enhancer binding factor 2, 45kDa	0.044
LDB2	LIM domain binding 2	0.043
ZNF195	zinc finger protein 195	0.043	Human
DOK4	docking protein 4	0.043
IL2RB	interleukin 2 receptor, beta	0.043
TNFRSF10C	tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain	0.043
ACTN1	actinin, alpha 1	0.043
HIVEP1	human immunodeficiency virus type I enhancer binding protein 1	0.043
HSF2	heat shock transcription factor 2	0.043
C17orf28	chromosome 17 open reading frame 28	0.043
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.043	Rat
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.043
MAGEB18	melanoma antigen family B, 18	0.043
PARD3	par-3 partitioning defective 3 homolog (C. elegans)	0.043
STUB1	STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase	0.043
MYST3	MYST histone acetyltransferase (monocytic leukemia) 3	0.042
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.042
FOSL2	FOS-like antigen 2	0.042
WDR1	WD repeat domain 1	0.042
TYK2	tyrosine kinase 2	0.042
TRAF1	TNF receptor-associated factor 1	0.042
IL1RN	interleukin 1 receptor antagonist	0.042
RNPS1	RNA binding protein S1, serine-rich domain	0.042
NRG1	neuregulin 1	0.042
MAPK10	mitogen-activated protein kinase 10	0.042	Fly
REEP5	receptor accessory protein 5	0.042
AXIN2	axin 2	0.042
LARP1	La ribonucleoprotein domain family, member 1	0.042
SASH3	SAM and SH3 domain containing 3	0.042
EIF1AY	eukaryotic translation initiation factor 1A, Y-linked	0.042
LDLR	low density lipoprotein receptor	0.042
CBX8	chromobox homolog 8	0.042
GDF10	growth differentiation factor 10	0.042	Human
MAP7D1	MAP7 domain containing 1	0.042
UBE2A	ubiquitin-conjugating enzyme E2A (RAD6 homolog)	0.042	Human Fly
CEP55	centrosomal protein 55kDa	0.042
TGFB3	transforming growth factor, beta 3	0.042
PPIG	peptidylprolyl isomerase G (cyclophilin G)	0.042
RPS6KA4	ribosomal protein S6 kinase, 90kDa, polypeptide 4	0.041
BTBD7	BTB (POZ) domain containing 7	0.041
SOX2	SRY (sex determining region Y)-box 2	0.041
YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	0.041
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.041