IMP: Integrative Multi-species Prediction

Homo sapiens

170 genes annotated in human

Multi-species View

peptidyl tyrosine modification

GO:0018212

The modification of peptidyl-tyrosine.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "peptidyl tyrosine modification"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "peptidyl tyrosine modification" (in gray)

Name	Description	Probability	Func Analog Organism
EGFR	epidermal growth factor receptor	1.000
ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	1.000
PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	1.000
SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)	1.000
CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	1.000	Human Fly
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	1.000
ITGB1	integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)	1.000	Human Rat
PTPN1	protein tyrosine phosphatase, non-receptor type 1	1.000	Human
PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	0.998
SHC1	SHC (Src homology 2 domain containing) transforming protein 1	0.998
LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)	0.998
WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	0.998
LCK	lymphocyte-specific protein tyrosine kinase	0.996
PDGFRB	platelet-derived growth factor receptor, beta polypeptide	0.996
PTPRC	protein tyrosine phosphatase, receptor type, C	0.996	Mouse
MET	met proto-oncogene (hepatocyte growth factor receptor)	0.996	Human Mouse Rat
LAT	linker for activation of T cells	0.994
FN1	fibronectin 1	0.989
MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	0.988
EPOR	erythropoietin receptor	0.987
BCAR1	breast cancer anti-estrogen resistance 1	0.983
STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	0.979
VAV1	vav 1 guanine nucleotide exchange factor	0.979
VEGFA	vascular endothelial growth factor A	0.978
SOCS3	suppressor of cytokine signaling 3	0.978	Human
IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	0.976
SYK	spleen tyrosine kinase	0.961
LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog	0.959
FGF1	fibroblast growth factor 1 (acidic)	0.957	Human
PLCG1	phospholipase C, gamma 1	0.956
FHL2	four and a half LIM domains 2	0.955
NCK1	NCK adaptor protein 1	0.948
ITGB3	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	0.945
AXL	AXL receptor tyrosine kinase	0.938	Human
PDGFB	platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)	0.931
FLT1	fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)	0.928
FGFR2	fibroblast growth factor receptor 2	0.921
FLNA	filamin A, alpha	0.919
SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	0.900
NTRK1	neurotrophic tyrosine kinase, receptor, type 1	0.895
ZAP70	zeta-chain (TCR) associated protein kinase 70kDa	0.895
SH2D1A	SH2 domain containing 1A	0.887
TEK	TEK tyrosine kinase, endothelial	0.880
PTK2	PTK2 protein tyrosine kinase 2	0.877
CCR5	chemokine (C-C motif) receptor 5	0.872
PDIA3	protein disulfide isomerase family A, member 3	0.858
PTPN6	protein tyrosine phosphatase, non-receptor type 6	0.854
ESR1	estrogen receptor 1	0.832
TAL1	T-cell acute lymphocytic leukemia 1	0.823
CD3E	CD3e molecule, epsilon (CD3-TCR complex)	0.797	Mouse
FBN1	fibrillin 1	0.793
ATN1	atrophin 1	0.786
INSR	insulin receptor	0.780
IQGAP1	IQ motif containing GTPase activating protein 1	0.767
ADAM19	ADAM metallopeptidase domain 19	0.764	Human
IL6	interleukin 6 (interferon, beta 2)	0.761
EPHA2	EPH receptor A2	0.756
VCAM1	vascular cell adhesion molecule 1	0.744
SOCS1	suppressor of cytokine signaling 1	0.743	Human Mouse
PAK2	p21 protein (Cdc42/Rac)-activated kinase 2	0.737
FGFR1	fibroblast growth factor receptor 1	0.726
GHR	growth hormone receptor	0.711	Mouse Rat
FYN	FYN oncogene related to SRC, FGR, YES	0.698
GAB1	GRB2-associated binding protein 1	0.689
PAG1	phosphoprotein associated with glycosphingolipid microdomains 1	0.686
SH2D4A	SH2 domain containing 4A	0.678
ITGA5	integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	0.676
FBLN1	fibulin 1	0.674	Human
LTBP4	latent transforming growth factor beta binding protein 4	0.667	Human
COL6A2	collagen, type VI, alpha 2	0.661
MAPK1	mitogen-activated protein kinase 1	0.660	Human
ADAM15	ADAM metallopeptidase domain 15	0.651	Human
CD44	CD44 molecule (Indian blood group)	0.647
PLAU	plasminogen activator, urokinase	0.638	Human
MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2	0.621
KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	0.609
ICAM1	intercellular adhesion molecule 1	0.607
TNF	tumor necrosis factor	0.598
HSPG2	heparan sulfate proteoglycan 2	0.591
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.589	Human
IGF1R	insulin-like growth factor 1 receptor	0.583
JAK2	Janus kinase 2	0.582
SFN	stratifin	0.573
FLNB	filamin B, beta	0.561
PECAM1	platelet/endothelial cell adhesion molecule	0.554
SLC9A3R1	solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1	0.552
PRKCA	protein kinase C, alpha	0.549	Mouse
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.539	Human
TLN1	talin 1	0.514
CD247	CD247 molecule	0.514
ZNF746	zinc finger protein 746	0.514
MAP3K5	mitogen-activated protein kinase kinase kinase 5	0.510
KHDRBS1	KH domain containing, RNA binding, signal transduction associated 1	0.509
IGFBP5	insulin-like growth factor binding protein 5	0.508
IL6R	interleukin 6 receptor	0.504
CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	0.497	Human
MSN	moesin	0.496	Human
GRB7	growth factor receptor-bound protein 7	0.494
KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	0.491
BTK	Bruton agammaglobulinemia tyrosine kinase	0.490
CAV1	caveolin 1, caveolae protein, 22kDa	0.483	Mouse
ENG	endoglin	0.482
OSMR	oncostatin M receptor	0.475	Human
NCKAP1	NCK-associated protein 1	0.470
LTBP2	latent transforming growth factor beta binding protein 2	0.462	Human
PTEN	phosphatase and tensin homolog	0.442
CD2	CD2 molecule	0.441
ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)	0.440	Human
JAK3	Janus kinase 3	0.438	Human Mouse Rat
DLG1	discs, large homolog 1 (Drosophila)	0.436
MPDZ	multiple PDZ domain protein	0.436
PDCD6IP	programmed cell death 6 interacting protein	0.429
ARRB1	arrestin, beta 1	0.428
PTPRB	protein tyrosine phosphatase, receptor type, B	0.426
NTRK2	neurotrophic tyrosine kinase, receptor, type 2	0.422
PRKCB	protein kinase C, beta	0.420
TRAF1	TNF receptor-associated factor 1	0.419
ABI2	abl-interactor 2	0.418
BLNK	B-cell linker	0.416
PTK2B	PTK2B protein tyrosine kinase 2 beta	0.403
GRB2	growth factor receptor-bound protein 2	0.399	Fly
STAT4	signal transducer and activator of transcription 4	0.399
INHBA	inhibin, beta A	0.397
CD28	CD28 molecule	0.392
LRRK2	leucine-rich repeat kinase 2	0.388
BIRC3	baculoviral IAP repeat containing 3	0.388
RIN1	Ras and Rab interactor 1	0.384
ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)	0.381	Human
NRP2	neuropilin 2	0.378	Human
LZTS2	leucine zipper, putative tumor suppressor 2	0.376
GH2	growth hormone 2	0.375	Human
GAS6	growth arrest-specific 6	0.370
CD9	CD9 molecule	0.370	Human
TRAF5	TNF receptor-associated factor 5	0.370
FBLN5	fibulin 5	0.366	Human
CD84	CD84 molecule	0.365
NRP1	neuropilin 1	0.360
PLAT	plasminogen activator, tissue	0.355	Human
PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	0.353
COL1A1	collagen, type I, alpha 1	0.351
COL6A1	collagen, type VI, alpha 1	0.342
HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	0.340
TNC	tenascin C	0.340
FASLG	Fas ligand (TNF superfamily, member 6)	0.337
PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	0.334
PLAUR	plasminogen activator, urokinase receptor	0.331
YAP1	Yes-associated protein 1	0.328
APBB1	amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)	0.324
IL2RB	interleukin 2 receptor, beta	0.324
VHL	von Hippel-Lindau tumor suppressor	0.323
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.322
SHC3	SHC (Src homology 2 domain containing) transforming protein 3	0.319
SORBS3	sorbin and SH3 domain containing 3	0.319
STAB1	stabilin 1	0.318
ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)	0.316
NCF1	neutrophil cytosolic factor 1	0.316
CD86	CD86 molecule	0.310
MARK2	MAP/microtubule affinity-regulating kinase 2	0.309
PSEN2	presenilin 2 (Alzheimer disease 4)	0.308	Mouse
MED28	mediator complex subunit 28	0.307
FGF7	fibroblast growth factor 7	0.307
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.305
TBX5	T-box 5	0.293
CTNND1	catenin (cadherin-associated protein), delta 1	0.289
THBS1	thrombospondin 1	0.288	Human
SH3BP2	SH3-domain binding protein 2	0.288
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.286
FYB	FYN binding protein	0.285
ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	0.285
GRB10	growth factor receptor-bound protein 10	0.276
ZNF496	zinc finger protein 496	0.272
ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	0.271	Human
GIT2	G protein-coupled receptor kinase interacting ArfGAP 2	0.271
TFF1	trefoil factor 1	0.271
GDF9	growth differentiation factor 9	0.269
ITGB4	integrin, beta 4	0.264
CXCL9	chemokine (C-X-C motif) ligand 9	0.262
ILK	integrin-linked kinase	0.261
MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1	0.260
CCR7	chemokine (C-C motif) receptor 7	0.259
EMILIN1	elastin microfibril interfacer 1	0.259
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.255
CSF2RB	colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)	0.253
CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like	0.252
SNX9	sorting nexin 9	0.252
TGFB2	transforming growth factor, beta 2	0.249
LIFR	leukemia inhibitory factor receptor alpha	0.248	Human
NTRK3	neurotrophic tyrosine kinase, receptor, type 3	0.247	Human
JAK1	Janus kinase 1	0.247
RUNX1	runt-related transcription factor 1	0.247
PGF	placental growth factor	0.245	Human
CFLAR	CASP8 and FADD-like apoptosis regulator	0.243
SIRT1	sirtuin 1	0.242
CDH5	cadherin 5, type 2 (vascular endothelium)	0.241
SLAMF1	signaling lymphocytic activation molecule family member 1	0.239
RANBP9	RAN binding protein 9	0.238
CSK	c-src tyrosine kinase	0.238	Rat
CTGF	connective tissue growth factor	0.236
WASL	Wiskott-Aldrich syndrome-like	0.233
SOCS5	suppressor of cytokine signaling 5	0.231
MAGEA11	melanoma antigen family A, 11	0.230
SLA	Src-like-adaptor	0.228
ANGPT1	angiopoietin 1	0.228
IRF4	interferon regulatory factor 4	0.227
CCL2	chemokine (C-C motif) ligand 2	0.225	Human
CAV2	caveolin 2	0.223
FGG	fibrinogen gamma chain	0.223
ITGB5	integrin, beta 5	0.223	Human
CXCL12	chemokine (C-X-C motif) ligand 12	0.219
NCF4	neutrophil cytosolic factor 4, 40kDa	0.218
NOXA1	NADPH oxidase activator 1	0.217
SOS1	son of sevenless homolog 1 (Drosophila)	0.216
CDK11B	cyclin-dependent kinase 11B	0.215
FGF2	fibroblast growth factor 2 (basic)	0.215	Human
HCLS1	hematopoietic cell-specific Lyn substrate 1	0.215
TRADD	TNFRSF1A-associated via death domain	0.214
CXCR4	chemokine (C-X-C motif) receptor 4	0.213
IFNAR2	interferon (alpha, beta and omega) receptor 2	0.212
IGFBP3	insulin-like growth factor binding protein 3	0.208
PTGIS	prostaglandin I2 (prostacyclin) synthase	0.207
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.206	Human
TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	0.204
FRS2	fibroblast growth factor receptor substrate 2	0.203
TENC1	tensin like C1 domain containing phosphatase (tensin 2)	0.203
EPHA7	EPH receptor A7	0.202
PRR5	proline rich 5 (renal)	0.201
PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha	0.199
ITGA6	integrin, alpha 6	0.199	Human
NKX2-5	NK2 transcription factor related, locus 5 (Drosophila)	0.195
MUC1	mucin 1, cell surface associated	0.195
PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	0.192
NGFR	nerve growth factor receptor	0.192
CD63	CD63 molecule	0.191
CD81	CD81 molecule	0.191
SPRR2A	small proline-rich protein 2A	0.190
COL5A1	collagen, type V, alpha 1	0.188
CSH2	chorionic somatomammotropin hormone 2	0.187	Human
GH1	growth hormone 1	0.187
TGM2	transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)	0.187
PRKAB1	protein kinase, AMP-activated, beta 1 non-catalytic subunit	0.186
RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	0.185
CUL2	cullin 2	0.184
STC1	stanniocalcin 1	0.182
STRADA	STE20-related kinase adaptor alpha	0.182
FGA	fibrinogen alpha chain	0.182
PHLDA1	pleckstrin homology-like domain, family A, member 1	0.179
LOXL1	lysyl oxidase-like 1	0.176
EFNA1	ephrin-A1	0.175
OSM	oncostatin M	0.175
TNFRSF9	tumor necrosis factor receptor superfamily, member 9	0.175
IER3	immediate early response 3	0.172
PTPN12	protein tyrosine phosphatase, non-receptor type 12	0.168
ELN	elastin	0.167
TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	0.167
LOXL2	lysyl oxidase-like 2	0.167
UBASH3B	ubiquitin associated and SH3 domain containing B	0.167
STK10	serine/threonine kinase 10	0.166
DUSP23	dual specificity phosphatase 23	0.165
DARC	Duffy blood group, chemokine receptor	0.161
DCAF7	DDB1 and CUL4 associated factor 7	0.160
CCL18	chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)	0.160	Human
LDLR	low density lipoprotein receptor	0.160
CD274	CD274 molecule	0.159
TIMP3	TIMP metallopeptidase inhibitor 3	0.158
WIPF1	WAS/WASL interacting protein family, member 1	0.158
PRRX1	paired related homeobox 1	0.155
TSPAN4	tetraspanin 4	0.155
TIMP1	TIMP metallopeptidase inhibitor 1	0.153
IL22	interleukin 22	0.153
IFNG	interferon, gamma	0.152
ADAM10	ADAM metallopeptidase domain 10	0.151
TRIP6	thyroid hormone receptor interactor 6	0.150
NKG7	natural killer cell group 7 sequence	0.149
PRNP	prion protein	0.149
DNM2	dynamin 2	0.148
CDC25B	cell division cycle 25 homolog B (S. pombe)	0.147
CTLA4	cytotoxic T-lymphocyte-associated protein 4	0.147
ITGB1BP3	integrin beta 1 binding protein 3	0.147
ALK	anaplastic lymphoma receptor tyrosine kinase	0.145
CDCP1	CUB domain containing protein 1	0.143
ANGPT2	angiopoietin 2	0.143	Human
TXN	thioredoxin	0.143
IL2RA	interleukin 2 receptor, alpha	0.143
CSF1R	colony stimulating factor 1 receptor	0.143
CDC37	cell division cycle 37 homolog (S. cerevisiae)	0.141
RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	0.140
KLRD1	killer cell lectin-like receptor subfamily D, member 1	0.140
MAPK10	mitogen-activated protein kinase 10	0.140
BGN	biglycan	0.139
GFPT2	glutamine-fructose-6-phosphate transaminase 2	0.138
CHRD	chordin	0.137
MAPT	microtubule-associated protein tau	0.137
MAP2	microtubule-associated protein 2	0.135
ADH1B	alcohol dehydrogenase 1B (class I), beta polypeptide	0.135
IL1B	interleukin 1, beta	0.134
MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	0.133
SH2D2A	SH2 domain containing 2A	0.133
BAD	BCL2-associated agonist of cell death	0.133
CSF3	colony stimulating factor 3 (granulocyte)	0.132
RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	0.132
DYRK4	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4	0.132	Human
KITLG	KIT ligand	0.132	Mouse
HGF	hepatocyte growth factor (hepapoietin A; scatter factor)	0.131
CXCL2	chemokine (C-X-C motif) ligand 2	0.130
EPHA3	EPH receptor A3	0.130
PLOD2	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2	0.129
VAV2	vav 2 guanine nucleotide exchange factor	0.129
STC2	stanniocalcin 2	0.129
IL7R	interleukin 7 receptor	0.129
CCL7	chemokine (C-C motif) ligand 7	0.129	Human
MYH9	myosin, heavy chain 9, non-muscle	0.128
FCGR3B	Fc fragment of IgG, low affinity IIIb, receptor (CD16b)	0.127
VEGFC	vascular endothelial growth factor C	0.127	Human Mouse
PLEK	pleckstrin	0.126
SHC2	SHC (Src homology 2 domain containing) transforming protein 2	0.126
CSF1	colony stimulating factor 1 (macrophage)	0.126
LGALS1	lectin, galactoside-binding, soluble, 1	0.126
GAB2	GRB2-associated binding protein 2	0.125
ANGPTL4	angiopoietin-like 4	0.125
ACVRL1	activin A receptor type II-like 1	0.125
NOV	nephroblastoma overexpressed gene	0.125
UHRF2	ubiquitin-like with PHD and ring finger domains 2	0.124
CXCR6	chemokine (C-X-C motif) receptor 6	0.123
LIF	leukemia inhibitory factor (cholinergic differentiation factor)	0.123
CSF2RA	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	0.123
SPTBN1	spectrin, beta, non-erythrocytic 1	0.122
FCGR2A	Fc fragment of IgG, low affinity IIa, receptor (CD32)	0.122
BMP1	bone morphogenetic protein 1	0.122
DCN	decorin	0.122
SCHIP1	schwannomin interacting protein 1	0.121
RHOU	ras homolog gene family, member U	0.121
SFRP1	secreted frizzled-related protein 1	0.121
MMP16	matrix metallopeptidase 16 (membrane-inserted)	0.120
DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	0.120
LAMC2	laminin, gamma 2	0.119
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.119
SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	0.118
MMP1	matrix metallopeptidase 1 (interstitial collagenase)	0.117
IL4	interleukin 4	0.117	Mouse
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.117
APOH	apolipoprotein H (beta-2-glycoprotein I)	0.116
PTPN3	protein tyrosine phosphatase, non-receptor type 3	0.116
PPHLN1	periphilin 1	0.115
DVL2	dishevelled, dsh homolog 2 (Drosophila)	0.115	Mouse
IDE	insulin-degrading enzyme	0.115
ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B	0.114
PSTPIP1	proline-serine-threonine phosphatase interacting protein 1	0.113
SNIP1	Smad nuclear interacting protein 1	0.113
HCK	hemopoietic cell kinase	0.113
FMOD	fibromodulin	0.112
CXCL13	chemokine (C-X-C motif) ligand 13	0.112
ANGPTL2	angiopoietin-like 2	0.111	Human
IL21R	interleukin 21 receptor	0.111
FNIP1	folliculin interacting protein 1	0.110
WNT2	wingless-type MMTV integration site family member 2	0.110
SMAD3	SMAD family member 3	0.110
PTPRF	protein tyrosine phosphatase, receptor type, F	0.110
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.110
TCIRG1	T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3	0.110
PRKCQ	protein kinase C, theta	0.109	Human
FES	feline sarcoma oncogene	0.108
FSTL3	follistatin-like 3 (secreted glycoprotein)	0.108
IL12RB1	interleukin 12 receptor, beta 1	0.108	Mouse
EFNA5	ephrin-A5	0.108	Human
TBXA2R	thromboxane A2 receptor	0.107
KLF13	Kruppel-like factor 13	0.107
SRPX	sushi-repeat containing protein, X-linked	0.107
NTF3	neurotrophin 3	0.107
STK38	serine/threonine kinase 38	0.106
AKAP12	A kinase (PRKA) anchor protein 12	0.106
HDAC6	histone deacetylase 6	0.105
TCEB2	transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)	0.105
FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog	0.105
ARL2	ADP-ribosylation factor-like 2	0.104
CLIC4	chloride intracellular channel 4	0.104
CCL5	chemokine (C-C motif) ligand 5	0.103
MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3	0.103
COL2A1	collagen, type II, alpha 1	0.103
IL12RB2	interleukin 12 receptor, beta 2	0.103	Human Mouse
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.102
PROX1	prospero homeobox 1	0.101
PDGFC	platelet derived growth factor C	0.101	Mouse
CXCL5	chemokine (C-X-C motif) ligand 5	0.100
ZBTB16	zinc finger and BTB domain containing 16	0.099
CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)	0.099
EZR	ezrin	0.099	Human
YES1	v-yes-1 Yamaguchi sarcoma viral oncogene homolog 1	0.099
ADRBK1	adrenergic, beta, receptor kinase 1	0.099
IL23A	interleukin 23, alpha subunit p19	0.098
FLT4	fms-related tyrosine kinase 4	0.098
CCDC6	coiled-coil domain containing 6	0.098
PML	promyelocytic leukemia	0.098
TBX21	T-box 21	0.097
NTF4	neurotrophin 4	0.097	Human
DYRK1B	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B	0.097	Human Yeast
FGF6	fibroblast growth factor 6	0.096	Human
NGF	nerve growth factor (beta polypeptide)	0.096	Human
CASP3	caspase 3, apoptosis-related cysteine peptidase	0.096
CDK17	cyclin-dependent kinase 17	0.096
NOTCH3	notch 3	0.096
SLIT3	slit homolog 3 (Drosophila)	0.095
CCR1	chemokine (C-C motif) receptor 1	0.095
CASP10	caspase 10, apoptosis-related cysteine peptidase	0.095
MSC	musculin	0.095
BAK1	BCL2-antagonist/killer 1	0.095
TM4SF1	transmembrane 4 L six family member 1	0.095
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.094
HAS2	hyaluronan synthase 2	0.094
AGTR1	angiotensin II receptor, type 1	0.094	Rat
FPR3	formyl peptide receptor 3	0.093
IL11	interleukin 11	0.093
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.093
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.092
CCL11	chemokine (C-C motif) ligand 11	0.092	Human
TRAF2	TNF receptor-associated factor 2	0.092
JAG2	jagged 2	0.091
MMP14	matrix metallopeptidase 14 (membrane-inserted)	0.091
MMP19	matrix metallopeptidase 19	0.091
EPS8	epidermal growth factor receptor pathway substrate 8	0.090
CSNK1E	casein kinase 1, epsilon	0.090
IL12B	interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)	0.090
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.090
IGFBP4	insulin-like growth factor binding protein 4	0.090
ADRB2	adrenergic, beta-2-, receptor, surface	0.089	Human
NNMT	nicotinamide N-methyltransferase	0.089
IGF2R	insulin-like growth factor 2 receptor	0.089
LENG8	leukocyte receptor cluster (LRC) member 8	0.088
DDR2	discoidin domain receptor tyrosine kinase 2	0.088
IFNAR1	interferon (alpha, beta and omega) receptor 1	0.087
DAPK1	death-associated protein kinase 1	0.087
FGF8	fibroblast growth factor 8 (androgen-induced)	0.087
STAT5B	signal transducer and activator of transcription 5B	0.086
IL1A	interleukin 1, alpha	0.086
APBB2	amyloid beta (A4) precursor protein-binding, family B, member 2	0.086
RGS16	regulator of G-protein signaling 16	0.085
IL10	interleukin 10	0.085
CALD1	caldesmon 1	0.085
PAPPA	pregnancy-associated plasma protein A, pappalysin 1	0.084
CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	0.084	Human Fly
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.084
DAB2	disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)	0.084
DKK1	dickkopf homolog 1 (Xenopus laevis)	0.084
COL6A3	collagen, type VI, alpha 3	0.084
IL32	interleukin 32	0.083
PTGER3	prostaglandin E receptor 3 (subtype EP3)	0.083
SELPLG	selectin P ligand	0.083
PIK3R3	phosphoinositide-3-kinase, regulatory subunit 3 (gamma)	0.083
PDX1	pancreatic and duodenal homeobox 1	0.083
CSNK1A1	casein kinase 1, alpha 1	0.083
SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2	0.083
TNK2	tyrosine kinase, non-receptor, 2	0.082
EFNB1	ephrin-B1	0.082	Human
SH3D19	SH3 domain containing 19	0.082
ANGPT4	angiopoietin 4	0.082
FZD7	frizzled homolog 7 (Drosophila)	0.082
STAT5A	signal transducer and activator of transcription 5A	0.082	Mouse
PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	0.082
IL9	interleukin 9	0.082
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.081
PPP1R2	protein phosphatase 1, regulatory (inhibitor) subunit 2	0.081
LAMB2	laminin, beta 2 (laminin S)	0.081
AHNAK	AHNAK nucleoprotein	0.080
EGF	epidermal growth factor	0.080
TNS4	tensin 4	0.080
MMP11	matrix metallopeptidase 11 (stromelysin 3)	0.080
PSEN1	presenilin 1	0.079	Mouse
ACTB	actin, beta	0.079
BDNF	brain-derived neurotrophic factor	0.079	Human
TIE1	tyrosine kinase with immunoglobulin-like and EGF-like domains 1	0.079	Human
ITGAX	integrin, alpha X (complement component 3 receptor 4 subunit)	0.079
PRODH2	proline dehydrogenase (oxidase) 2	0.079
IGF1	insulin-like growth factor 1 (somatomedin C)	0.078
ITGA1	integrin, alpha 1	0.078	Human
EFNB2	ephrin-B2	0.078
HMGA2	high mobility group AT-hook 2	0.077
PTPRZ1	protein tyrosine phosphatase, receptor-type, Z polypeptide 1	0.077	Rat
CAPN1	calpain 1, (mu/I) large subunit	0.077
F2RL1	coagulation factor II (thrombin) receptor-like 1	0.077	Human
IGFBP6	insulin-like growth factor binding protein 6	0.076
TFPI2	tissue factor pathway inhibitor 2	0.076
SFRP4	secreted frizzled-related protein 4	0.076
VAV3	vav 3 guanine nucleotide exchange factor	0.076
ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)	0.076
TGFBI	transforming growth factor, beta-induced, 68kDa	0.076
NR0B2	nuclear receptor subfamily 0, group B, member 2	0.075
RBMS3	RNA binding motif, single stranded interacting protein 3	0.075
MYO10	myosin X	0.075
PLXNB1	plexin B1	0.075
IL10RA	interleukin 10 receptor, alpha	0.075
LPAR1	lysophosphatidic acid receptor 1	0.074
CNTF	ciliary neurotrophic factor	0.073
FHL1	four and a half LIM domains 1	0.073
DLG5	discs, large homolog 5 (Drosophila)	0.073
CD7	CD7 molecule	0.073
GZMB	granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)	0.073
LTK	leukocyte receptor tyrosine kinase	0.073	Human Fly
SNAI1	snail homolog 1 (Drosophila)	0.072
RGS4	regulator of G-protein signaling 4	0.072
IFNB1	interferon, beta 1, fibroblast	0.072	Human
HNF1B	HNF1 homeobox B	0.072
FGF10	fibroblast growth factor 10	0.072
HK2	hexokinase 2	0.072
HLA-DOA	major histocompatibility complex, class II, DO alpha	0.072
ITGB7	integrin, beta 7	0.071	Human
C1orf63	chromosome 1 open reading frame 63	0.071
CCL1	chemokine (C-C motif) ligand 1	0.071
TP73	tumor protein p73	0.071
PTRF	polymerase I and transcript release factor	0.071
GP1BA	glycoprotein Ib (platelet), alpha polypeptide	0.071
F2	coagulation factor II (thrombin)	0.071
CRIP2	cysteine-rich protein 2	0.071
IDUA	iduronidase, alpha-L-	0.071
CD151	CD151 molecule (Raph blood group)	0.071
CCNT2	cyclin T2	0.070
MYO1C	myosin IC	0.070
EPHB4	EPH receptor B4	0.070
HLA-DPA1	major histocompatibility complex, class II, DP alpha 1	0.070
F2RL3	coagulation factor II (thrombin) receptor-like 3	0.069
GAS7	growth arrest-specific 7	0.069
IL8	interleukin 8	0.069
RTKN	rhotekin	0.069
TBX2	T-box 2	0.069
CHST3	carbohydrate (chondroitin 6) sulfotransferase 3	0.069
CCL13	chemokine (C-C motif) ligand 13	0.069	Human
CUX1	cut-like homeobox 1	0.069
PREX1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	0.068
GNLY	granulysin	0.068
COL11A2	collagen, type XI, alpha 2	0.068
MYO1F	myosin IF	0.068
RAMP2	receptor (G protein-coupled) activity modifying protein 2	0.068
GCGR	glucagon receptor	0.068
WNT1	wingless-type MMTV integration site family, member 1	0.067
C1QA	complement component 1, q subcomponent, A chain	0.067
ITIH3	inter-alpha (globulin) inhibitor H3	0.067
CYBA	cytochrome b-245, alpha polypeptide	0.067
PLXDC1	plexin domain containing 1	0.067
AGRN	agrin	0.067
FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide	0.067
CDK9	cyclin-dependent kinase 9	0.067
CCKBR	cholecystokinin B receptor	0.067
RGS3	regulator of G-protein signaling 3	0.067
TGFA	transforming growth factor, alpha	0.067
CSHL1	chorionic somatomammotropin hormone-like 1	0.066	Human
PRF1	perforin 1 (pore forming protein)	0.066
COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)	0.066
NCK2	NCK adaptor protein 2	0.066
PDCD1LG2	programmed cell death 1 ligand 2	0.066
IGFBP1	insulin-like growth factor binding protein 1	0.066
CCL22	chemokine (C-C motif) ligand 22	0.066
ADAM9	ADAM metallopeptidase domain 9	0.066	Human
IL13	interleukin 13	0.066
BCR	breakpoint cluster region	0.066
NBL1	neuroblastoma, suppression of tumorigenicity 1	0.065
CNTN1	contactin 1	0.065
PRR5L	proline rich 5 like	0.065
DPT	dermatopontin	0.065
EXT1	exostosin 1	0.065
MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	0.065
HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1	0.064
ARRDC3	arrestin domain containing 3	0.064
LAG3	lymphocyte-activation gene 3	0.064
RASGRF1	Ras protein-specific guanine nucleotide-releasing factor 1	0.064
E2F3	E2F transcription factor 3	0.064
NOS2	nitric oxide synthase 2, inducible	0.064
FGFR4	fibroblast growth factor receptor 4	0.064
MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1	0.064
IL3	interleukin 3 (colony-stimulating factor, multiple)	0.064
COL14A1	collagen, type XIV, alpha 1	0.064
CCR3	chemokine (C-C motif) receptor 3	0.063
MYLK	myosin light chain kinase	0.062
SSTR3	somatostatin receptor 3	0.062
HDAC2	histone deacetylase 2	0.062
HRH1	histamine receptor H1	0.062
CD37	CD37 molecule	0.062
DNM1	dynamin 1	0.062
PTHLH	parathyroid hormone-like hormone	0.062
IL9R	interleukin 9 receptor	0.061
MLN	motilin	0.061
PTPRJ	protein tyrosine phosphatase, receptor type, J	0.061
BAIAP2	BAI1-associated protein 2	0.061
SLAMF7	SLAM family member 7	0.061
MCF2	MCF.2 cell line derived transforming sequence	0.061
SULF1	sulfatase 1	0.061
IL3RA	interleukin 3 receptor, alpha (low affinity)	0.061
ROBO4	roundabout homolog 4, magic roundabout (Drosophila)	0.061
LRRC32	leucine rich repeat containing 32	0.060
HTR1B	5-hydroxytryptamine (serotonin) receptor 1B	0.060	Human
MTA3	metastasis associated 1 family, member 3	0.060
CD22	CD22 molecule	0.060
SPSB1	splA/ryanodine receptor domain and SOCS box containing 1	0.060
PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)	0.060
SIRPA	signal-regulatory protein alpha	0.060
TLR2	toll-like receptor 2	0.060
AHR	aryl hydrocarbon receptor	0.060
BMI1	BMI1 polycomb ring finger oncogene	0.060
PRKAG2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	0.060
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.060
PFKL	phosphofructokinase, liver	0.059
TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	0.059
CELA3B	chymotrypsin-like elastase family, member 3B	0.059
ECM1	extracellular matrix protein 1	0.059
CIITA	class II, major histocompatibility complex, transactivator	0.059
PRDM8	PR domain containing 8	0.059
CD163	CD163 molecule	0.058
PRKCD	protein kinase C, delta	0.058	Human Mouse
LUC7L	LUC7-like (S. cerevisiae)	0.058
THY1	Thy-1 cell surface antigen	0.058
CD34	CD34 molecule	0.058
STAT2	signal transducer and activator of transcription 2, 113kDa	0.058
CLU	clusterin	0.058
IL2RG	interleukin 2 receptor, gamma	0.058
DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A	0.058
CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)	0.058
PLA2G2D	phospholipase A2, group IID	0.058
SNAP23	synaptosomal-associated protein, 23kDa	0.058
HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1	0.058
SPAM1	sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)	0.058	Human
SAMD4B	sterile alpha motif domain containing 4B	0.058
CD14	CD14 molecule	0.058
PRELP	proline/arginine-rich end leucine-rich repeat protein	0.058
SPIB	Spi-B transcription factor (Spi-1/PU.1 related)	0.057
C5AR1	complement component 5a receptor 1	0.057
WISP2	WNT1 inducible signaling pathway protein 2	0.057
MCAM	melanoma cell adhesion molecule	0.057
SORBS2	sorbin and SH3 domain containing 2	0.057
SOCS6	suppressor of cytokine signaling 6	0.057	Human
KNG1	kininogen 1	0.057
FGFR3	fibroblast growth factor receptor 3	0.057
ESRRG	estrogen-related receptor gamma	0.057
BMP4	bone morphogenetic protein 4	0.056
TRAF4	TNF receptor-associated factor 4	0.056
PRKACA	protein kinase, cAMP-dependent, catalytic, alpha	0.056
CAPRIN2	caprin family member 2	0.056
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.056
EMP3	epithelial membrane protein 3	0.056
CD93	CD93 molecule	0.056
ADAMTS2	ADAM metallopeptidase with thrombospondin type 1 motif, 2	0.056
MAPK14	mitogen-activated protein kinase 14	0.056
PRKAG1	protein kinase, AMP-activated, gamma 1 non-catalytic subunit	0.056
CMKLR1	chemokine-like receptor 1	0.056
PTPRD	protein tyrosine phosphatase, receptor type, D	0.056
GGT5	gamma-glutamyltransferase 5	0.055
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.055
CSF2	colony stimulating factor 2 (granulocyte-macrophage)	0.055
FOXC2	forkhead box C2 (MFH-1, mesenchyme forkhead 1)	0.055
SEMA3C	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C	0.055
LEPR	leptin receptor	0.055	Human
OPRM1	opioid receptor, mu 1	0.055
NR4A3	nuclear receptor subfamily 4, group A, member 3	0.055
INO80B	INO80 complex subunit B	0.055
EPHA8	EPH receptor A8	0.055	Human Mouse Worm
C8A	complement component 8, alpha polypeptide	0.055
DRD1	dopamine receptor D1	0.055	Human
ICA1	islet cell autoantigen 1, 69kDa	0.055
MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)	0.054
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.054
PPP5C	protein phosphatase 5, catalytic subunit	0.054
TG	thyroglobulin	0.054
ADORA3	adenosine A3 receptor	0.054
CALR	calreticulin	0.054
PLSCR4	phospholipid scramblase 4	0.054
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.053
DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2	0.053
BTBD2	BTB (POZ) domain containing 2	0.053
LAIR1	leukocyte-associated immunoglobulin-like receptor 1	0.053
RELN	reelin	0.053	Mouse
CTSW	cathepsin W	0.053
PLTP	phospholipid transfer protein	0.053
MGP	matrix Gla protein	0.053
TP53BP2	tumor protein p53 binding protein, 2	0.053	Fly
RHOJ	ras homolog gene family, member J	0.053
APLP1	amyloid beta (A4) precursor-like protein 1	0.053
PTPN2	protein tyrosine phosphatase, non-receptor type 2	0.053
SIGLEC7	sialic acid binding Ig-like lectin 7	0.053
NUDT3	nudix (nucleoside diphosphate linked moiety X)-type motif 3	0.053
CCL8	chemokine (C-C motif) ligand 8	0.053	Human
CD40LG	CD40 ligand	0.053
FADD	Fas (TNFRSF6)-associated via death domain	0.053
STRADB	STE20-related kinase adaptor beta	0.052
MATK	megakaryocyte-associated tyrosine kinase	0.052
AEBP1	AE binding protein 1	0.052
KIF5B	kinesin family member 5B	0.052
TRAT1	T cell receptor associated transmembrane adaptor 1	0.052
LAMB3	laminin, beta 3	0.052
EPHA1	EPH receptor A1	0.052
CASP7	caspase 7, apoptosis-related cysteine peptidase	0.052
IL12A	interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)	0.052
MRC2	mannose receptor, C type 2	0.052
LOX	lysyl oxidase	0.052
SH3RF1	SH3 domain containing ring finger 1	0.052
CSF3R	colony stimulating factor 3 receptor (granulocyte)	0.052	Human
ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	0.052
PLOD1	procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 1	0.052
AKT2	v-akt murine thymoma viral oncogene homolog 2	0.052	Human
CCNE1	cyclin E1	0.052
TNS3	tensin 3	0.052
DLG4	discs, large homolog 4 (Drosophila)	0.051
TRIP10	thyroid hormone receptor interactor 10	0.051
APP	amyloid beta (A4) precursor protein	0.051	Mouse
KCNJ6	potassium inwardly-rectifying channel, subfamily J, member 6	0.051
GATA1	GATA binding protein 1 (globin transcription factor 1)	0.051
GIF	gastric intrinsic factor (vitamin B synthesis)	0.051
IL16	interleukin 16 (lymphocyte chemoattractant factor)	0.051
FRZB	frizzled-related protein	0.051
EGFL7	EGF-like-domain, multiple 7	0.051
C1R	complement component 1, r subcomponent	0.051
COL13A1	collagen, type XIII, alpha 1	0.051
NACAD	NAC alpha domain containing	0.051
SOX9	SRY (sex determining region Y)-box 9	0.051
PTPRA	protein tyrosine phosphatase, receptor type, A	0.051
ANKRD1	ankyrin repeat domain 1 (cardiac muscle)	0.051
GNMT	glycine N-methyltransferase	0.051
UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)	0.051
SASH3	SAM and SH3 domain containing 3	0.051
CALCRL	calcitonin receptor-like	0.050
SELE	selectin E	0.050
SPHK1	sphingosine kinase 1	0.050
GSN	gelsolin	0.050
SLCO2A1	solute carrier organic anion transporter family, member 2A1	0.050
FGF4	fibroblast growth factor 4	0.050	Human
VCL	vinculin	0.050
CD6	CD6 molecule	0.050
AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1	0.050
FHOD3	formin homology 2 domain containing 3	0.049
CD3G	CD3g molecule, gamma (CD3-TCR complex)	0.049
DDX4	DEAD (Asp-Glu-Ala-Asp) box polypeptide 4	0.049
NR5A1	nuclear receptor subfamily 5, group A, member 1	0.049
CLEC4M	C-type lectin domain family 4, member M	0.049
UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)	0.049
CYTH1	cytohesin 1	0.049
SH2B3	SH2B adaptor protein 3	0.049
CCL19	chemokine (C-C motif) ligand 19	0.049	Human
IRX4	iroquois homeobox 4	0.049
DLC1	deleted in liver cancer 1	0.049
DOK4	docking protein 4	0.049
CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	0.049
TF	transferrin	0.049
LMO2	LIM domain only 2 (rhombotin-like 1)	0.048
MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)	0.048
STAP2	signal transducing adaptor family member 2	0.048
FZD1	frizzled homolog 1 (Drosophila)	0.048
EDIL3	EGF-like repeats and discoidin I-like domains 3	0.048	Human
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.048
PYY	peptide YY	0.048
IRF5	interferon regulatory factor 5	0.048
NRG1	neuregulin 1	0.048
C1QTNF1	C1q and tumor necrosis factor related protein 1	0.048
PICALM	phosphatidylinositol binding clathrin assembly protein	0.048
NID1	nidogen 1	0.048
LTA	lymphotoxin alpha (TNF superfamily, member 1)	0.048