IMP: Integrative Multi-species Prediction

Homo sapiens

28 genes annotated in human

regulation of protein complex disassembly

Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "regulation of protein complex disassembly"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "regulation of protein complex disassembly" (in gray)

Name	Description	Probability	Func Analog Organism
ACTG1	actin, gamma 1	0.327
ACTB	actin, beta	0.082
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.064
TRAF6	TNF receptor-associated factor 6	0.054
TPM2	tropomyosin 2 (beta)	0.049	Worm
MYH9	myosin, heavy chain 9, non-muscle	0.047
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.043
SRSF2	serine/arginine-rich splicing factor 2	0.043
TEX11	testis expressed 11	0.042
CDK2	cyclin-dependent kinase 2	0.041
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.041
ITGB4	integrin, beta 4	0.041
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.039
TTN	titin	0.039
FLNA	filamin A, alpha	0.039
TPM1	tropomyosin 1 (alpha)	0.039	Worm
KIF1B	kinesin family member 1B	0.036
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.035
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.033
YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	0.032
MYPN	myopalladin	0.031
SQSTM1	sequestosome 1	0.030
TPM4	tropomyosin 4	0.030	Worm
ANKRD28	ankyrin repeat domain 28	0.028
CORO1C	coronin, actin binding protein, 1C	0.026
CENPJ	centromere protein J	0.025
PDLIM7	PDZ and LIM domain 7 (enigma)	0.024
IRAK2	interleukin-1 receptor-associated kinase 2	0.024	Human
TRIM63	tripartite motif containing 63	0.023
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.023
CKS2	CDC28 protein kinase regulatory subunit 2	0.023
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.022
ZYX	zyxin	0.021
EXOC1	exocyst complex component 1	0.021
CCNA2	cyclin A2	0.021
RBM8A	RNA binding motif protein 8A	0.021
DISC1	disrupted in schizophrenia 1	0.019
SASS6	spindle assembly 6 homolog (C. elegans)	0.019
FAM190B	family with sequence similarity 190, member B	0.019
EIF4A3	eukaryotic translation initiation factor 4A3	0.019
EID1	EP300 interacting inhibitor of differentiation 1	0.018
ACTN1	actinin, alpha 1	0.018
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.018
NXF1	nuclear RNA export factor 1	0.018
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.017
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.017
GLIS2	GLIS family zinc finger 2	0.017
SCP2	sterol carrier protein 2	0.017
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.017
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.016
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.016
ZC3H12A	zinc finger CCCH-type containing 12A	0.016
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.016
ATP13A2	ATPase type 13A2	0.016
LMNA	lamin A/C	0.016
KIF20A	kinesin family member 20A	0.016
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.015
RIPK3	receptor-interacting serine-threonine kinase 3	0.015
TRA2B	transformer 2 beta homolog (Drosophila)	0.015
PELI3	pellino homolog 3 (Drosophila)	0.015
IRAK3	interleukin-1 receptor-associated kinase 3	0.015
ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa	0.015
CDK1	cyclin-dependent kinase 1	0.015
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.014
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.014
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.014
FUNDC2	FUN14 domain containing 2	0.014
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.014
MARK2	MAP/microtubule affinity-regulating kinase 2	0.013
TAGLN2	transgelin 2	0.013
DHX9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	0.013
SRSF3	serine/arginine-rich splicing factor 3	0.013	Worm
SRSF10	serine/arginine-rich splicing factor 10	0.013
ADRBK1	adrenergic, beta, receptor kinase 1	0.013
CD14	CD14 molecule	0.013
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.013
OPTN	optineurin	0.013
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.012
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.012
ACTA1	actin, alpha 1, skeletal muscle	0.012
GNB5	guanine nucleotide binding protein (G protein), beta 5	0.012
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.012
EXOC7	exocyst complex component 7	0.012
KIF23	kinesin family member 23	0.012
CBFB	core-binding factor, beta subunit	0.012
SPTBN1	spectrin, beta, non-erythrocytic 1	0.012
CENPE	centromere protein E, 312kDa	0.012
APC	adenomatous polyposis coli	0.012
DST	dystonin	0.012	Fly
FUS	fused in sarcoma	0.012
MYD88	myeloid differentiation primary response gene (88)	0.012
TNIK	TRAF2 and NCK interacting kinase	0.012
EXOC2	exocyst complex component 2	0.011
INADL	InaD-like (Drosophila)	0.011
CAV1	caveolin 1, caveolae protein, 22kDa	0.011
SNAP23	synaptosomal-associated protein, 23kDa	0.011
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.011
CNN2	calponin 2	0.011
IRAK1	interleukin-1 receptor-associated kinase 1	0.011	Human
SMAD9	SMAD family member 9	0.011
SRSF1	serine/arginine-rich splicing factor 1	0.011	Yeast
BAIAP2	BAI1-associated protein 2	0.011
CCNE1	cyclin E1	0.011
SYPL1	synaptophysin-like 1	0.011
INCENP	inner centromere protein antigens 135/155kDa	0.011
RHOG	ras homolog gene family, member G (rho G)	0.010
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.010
CDKN3	cyclin-dependent kinase inhibitor 3	0.010
YBX1	Y box binding protein 1	0.010
LUC7L2	LUC7-like 2 (S. cerevisiae)	0.010
RACGAP1	Rac GTPase activating protein 1	0.010
SUFU	suppressor of fused homolog (Drosophila)	0.010
CCNB1	cyclin B1	0.010
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.010