IMP: Integrative Multi-species Prediction

Homo sapiens

52 genes annotated in human

protein complex disassembly

The disaggregation of a protein complex into its constituent components. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "protein complex disassembly"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "protein complex disassembly" (in gray)

Name	Description	Probability	Func Analog Organism
SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	0.998
SMARCC2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2	0.995
ARID1A	AT rich interactive domain 1A (SWI-like)	0.986
ACTG1	actin, gamma 1	0.983
ACTB	actin, beta	0.967
SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	0.910
ARID1B	AT rich interactive domain 1B (SWI1-like)	0.905	Human
HIST1H2BD	histone cluster 1, H2bd	0.878
HIST1H3D	histone cluster 1, H3d	0.875	Human
HIST1H1C	histone cluster 1, H1c	0.872
PBRM1	polybromo 1	0.835
HIST1H2BG	histone cluster 1, H2bg	0.808
EIF4A3	eukaryotic translation initiation factor 4A3	0.785
SRSF3	serine/arginine-rich splicing factor 3	0.772	Worm
HIST2H2BE	histone cluster 2, H2be	0.768
HIST1H2AC	histone cluster 1, H2ac	0.748	Human
ARID2	AT rich interactive domain 2 (ARID, RFX-like)	0.735
CFL1	cofilin 1 (non-muscle)	0.731	Human Yeast Mouse
SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1	0.727
HIST1H2BI	histone cluster 1, H2bi	0.669
HIST1H2BF	histone cluster 1, H2bf	0.637
RBM8A	RNA binding motif protein 8A	0.635
MAPRE1	microtubule-associated protein, RP/EB family, member 1	0.635
HSPA8	heat shock 70kDa protein 8	0.624	Yeast Mouse
CDK2	cyclin-dependent kinase 2	0.591
HIST1H2BC	histone cluster 1, H2bc	0.578
HIST1H2AE	histone cluster 1, H2ae	0.577	Human
SMARCA2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	0.575	Human Yeast
HIST1H2BE	histone cluster 1, H2be	0.539
SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	0.538
TPM1	tropomyosin 1 (alpha)	0.524	Worm
SQSTM1	sequestosome 1	0.492
MAGOH	mago-nashi homolog, proliferation-associated (Drosophila)	0.466
FUNDC2	FUN14 domain containing 2	0.425
HIST1H2BK	histone cluster 1, H2bk	0.418
SRSF2	serine/arginine-rich splicing factor 2	0.403
VCP	valosin containing protein	0.393	Yeast
BIRC5	baculoviral IAP repeat containing 5	0.349
CDK1	cyclin-dependent kinase 1	0.341
HIST1H2AI	histone cluster 1, H2ai	0.317	Human
LEO1	Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.316
YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	0.316
IRAK1	interleukin-1 receptor-associated kinase 1	0.306	Human
AMPH	amphiphysin	0.296
CKAP5	cytoskeleton associated protein 5	0.281
HIST2H2AA4	histone cluster 2, H2aa4	0.277	Human
CDCA8	cell division cycle associated 8	0.276
HIST1H2BH	histone cluster 1, H2bh	0.271
HIST1H3H	histone cluster 1, H3h	0.269
TEX11	testis expressed 11	0.267
APC	adenomatous polyposis coli	0.266
HIST1H2AJ	histone cluster 1, H2aj	0.263	Human
ATP13A2	ATPase type 13A2	0.261
AURKB	aurora kinase B	0.255
CBX5	chromobox homolog 5	0.254
TPM2	tropomyosin 2 (beta)	0.251	Worm
CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)	0.243
TRA2B	transformer 2 beta homolog (Drosophila)	0.207
ITGB4	integrin, beta 4	0.206
RIPK3	receptor-interacting serine-threonine kinase 3	0.194
HIST1H4H	histone cluster 1, H4h	0.189
MARK2	MAP/microtubule affinity-regulating kinase 2	0.188
PSEN2	presenilin 2 (Alzheimer disease 4)	0.180
XPO1	exportin 1 (CRM1 homolog, yeast)	0.179
INCENP	inner centromere protein antigens 135/155kDa	0.172
CENPJ	centromere protein J	0.169
TLK1	tousled-like kinase 1	0.168
CORO1C	coronin, actin binding protein, 1C	0.167
TUBA1C	tubulin, alpha 1c	0.167
SNAP23	synaptosomal-associated protein, 23kDa	0.163
KIF20A	kinesin family member 20A	0.162
SRSF10	serine/arginine-rich splicing factor 10	0.159
CARM1	coactivator-associated arginine methyltransferase 1	0.155
TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B	0.152
RTF1	Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.151
KIF1B	kinesin family member 1B	0.149
TUBA1B	tubulin, alpha 1b	0.139
ACTR2	ARP2 actin-related protein 2 homolog (yeast)	0.133
HIST1H2AM	histone cluster 1, H2am	0.132
TUBB	tubulin, beta	0.132
IRAK2	interleukin-1 receptor-associated kinase 2	0.131	Human
SIRT2	sirtuin 2	0.126
BRD7	bromodomain containing 7	0.121
CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	0.114
CCNA2	cyclin A2	0.111
MYH9	myosin, heavy chain 9, non-muscle	0.111
YBX1	Y box binding protein 1	0.110
RFX1	regulatory factor X, 1 (influences HLA class II expression)	0.109
BAG2	BCL2-associated athanogene 2	0.104
NCOR1	nuclear receptor corepressor 1	0.102
CKS1B	CDC28 protein kinase regulatory subunit 1B	0.101
FLNA	filamin A, alpha	0.101
ARRB2	arrestin, beta 2	0.098
HIST1H2BJ	histone cluster 1, H2bj	0.097
TRIM63	tripartite motif containing 63	0.097
HIST1H2AG	histone cluster 1, H2ag	0.097	Human
HIST1H3A	histone cluster 1, H3a	0.096
RACGAP1	Rac GTPase activating protein 1	0.095
MYD88	myeloid differentiation primary response gene (88)	0.093
PDLIM7	PDZ and LIM domain 7 (enigma)	0.093
TADA3	transcriptional adaptor 3	0.091
SORBS2	sorbin and SH3 domain containing 2	0.089
SCP2	sterol carrier protein 2	0.088
ACTN1	actinin, alpha 1	0.085
FANCA	Fanconi anemia, complementation group A	0.085
CCNB2	cyclin B2	0.084	Human
CENPE	centromere protein E, 312kDa	0.083
STX5	syntaxin 5	0.083
ZRANB1	zinc finger, RAN-binding domain containing 1	0.079
HNRNPM	heterogeneous nuclear ribonucleoprotein M	0.079
TPM4	tropomyosin 4	0.078	Worm
MCM10	minichromosome maintenance complex component 10	0.077
PPP2CA	protein phosphatase 2, catalytic subunit, alpha isozyme	0.077	Worm
PHLPP1	PH domain and leucine rich repeat protein phosphatase 1	0.077
SMARCE1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1	0.075
NBR1	neighbor of BRCA1 gene 1	0.074
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.074
DLGAP5	discs, large (Drosophila) homolog-associated protein 5	0.074
MRPL20	mitochondrial ribosomal protein L20	0.073
CD14	CD14 molecule	0.072
HIST1H2BM	histone cluster 1, H2bm	0.071
ANKRD28	ankyrin repeat domain 28	0.070
TTN	titin	0.070
SRSF6	serine/arginine-rich splicing factor 6	0.069
CDT1	chromatin licensing and DNA replication factor 1	0.068
NEK2	NIMA (never in mitosis gene a)-related kinase 2	0.068
HIST1H4D	histone cluster 1, H4d	0.068
BAIAP2	BAI1-associated protein 2	0.067
ADRBK1	adrenergic, beta, receptor kinase 1	0.067
COX17	COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)	0.067
TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3	0.067
SRSF1	serine/arginine-rich splicing factor 1	0.067	Yeast
TRAF6	TNF receptor-associated factor 6	0.065
PABPC1	poly(A) binding protein, cytoplasmic 1	0.064
CDAN1	congenital dyserythropoietic anemia, type I	0.063
RYBP	RING1 and YY1 binding protein	0.062
ZYX	zyxin	0.061
NCOR2	nuclear receptor corepressor 2	0.061
STAM	signal transducing adaptor molecule (SH3 domain and ITAM motif) 1	0.061
UPF1	UPF1 regulator of nonsense transcripts homolog (yeast)	0.060
TPX2	TPX2, microtubule-associated, homolog (Xenopus laevis)	0.060
MAP3K3	mitogen-activated protein kinase kinase kinase 3	0.060
EXOC2	exocyst complex component 2	0.059
HSPA1A	heat shock 70kDa protein 1A	0.059	Yeast
CAV1	caveolin 1, caveolae protein, 22kDa	0.059
TIRAP	toll-interleukin 1 receptor (TIR) domain containing adaptor protein	0.059
NSF	N-ethylmaleimide-sensitive factor	0.058	Yeast Fly
WDR20	WD repeat domain 20	0.058
HIST1H2AB	histone cluster 1, H2ab	0.058	Human
MOBKL1B	MOB1, Mps One Binder kinase activator-like 1B (yeast)	0.055
UPF3B	UPF3 regulator of nonsense transcripts homolog B (yeast)	0.055
HIST1H4B	histone cluster 1, H4b	0.055
GLIS2	GLIS family zinc finger 2	0.055
GNAI2	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2	0.054
SEPT2	septin 2	0.054
YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	0.054
CFL2	cofilin 2 (muscle)	0.053
DNAJB1	DnaJ (Hsp40) homolog, subfamily B, member 1	0.053
HIST2H4A	histone cluster 2, H4a	0.053
NPLOC4	nuclear protein localization 4 homolog (S. cerevisiae)	0.053	Yeast
SEPT7	septin 7	0.053
BAG3	BCL2-associated athanogene 3	0.053
TUBA1A	tubulin, alpha 1a	0.053
THOC4	THO complex 4	0.051
TOP2B	topoisomerase (DNA) II beta 180kDa	0.050
KIF4A	kinesin family member 4A	0.048
DSTN	destrin (actin depolymerizing factor)	0.047	Human Yeast Mouse
YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide	0.047
TSC22D3	TSC22 domain family, member 3	0.047
ACTA1	actin, alpha 1, skeletal muscle	0.047
EXOC7	exocyst complex component 7	0.046
WDR48	WD repeat domain 48	0.046
HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	0.045
ACOT7	acyl-CoA thioesterase 7	0.045
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.045
STX4	syntaxin 4	0.044
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	0.043
CDKN3	cyclin-dependent kinase inhibitor 3	0.043
ATF7IP	activating transcription factor 7 interacting protein	0.043
NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	0.043
CKS2	CDC28 protein kinase regulatory subunit 2	0.043
GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2	0.042
HIST1H3B	histone cluster 1, H3b	0.041
TAGLN2	transgelin 2	0.041
CCNB1	cyclin B1	0.041
HIST1H4E	histone cluster 1, H4e	0.041
EHD1	EH-domain containing 1	0.041
NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha	0.040	Yeast Mouse
CHMP1B	chromatin modifying protein 1B	0.040
KIF20B	kinesin family member 20B	0.040
SMAD9	SMAD family member 9	0.040
HIST1H3G	histone cluster 1, H3g	0.040
PELI3	pellino homolog 3 (Drosophila)	0.040
CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.039
CCDC85A	coiled-coil domain containing 85A	0.039
GNB5	guanine nucleotide binding protein (G protein), beta 5	0.038
RCOR1	REST corepressor 1	0.038
TUBGCP5	tubulin, gamma complex associated protein 5	0.038
HIST1H2BO	histone cluster 1, H2bo	0.038
DISC1	disrupted in schizophrenia 1	0.038
EEF1A1	eukaryotic translation elongation factor 1 alpha 1	0.038
HIST1H2AK	histone cluster 1, H2ak	0.037	Human
GPSM2	G-protein signaling modulator 2	0.037
KIF2C	kinesin family member 2C	0.037
CENPF	centromere protein F, 350/400kDa (mitosin)	0.037
PAIP2	poly(A) binding protein interacting protein 2	0.037
SPTBN1	spectrin, beta, non-erythrocytic 1	0.037
CDC20	cell division cycle 20 homolog (S. cerevisiae)	0.036
CDC7	cell division cycle 7 homolog (S. cerevisiae)	0.036
WASL	Wiskott-Aldrich syndrome-like	0.036
ETF1	eukaryotic translation termination factor 1	0.035
HIST1H2AL	histone cluster 1, H2al	0.035	Human
SVIL	supervillin	0.035
SMARCD2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2	0.035
HIST1H4A	histone cluster 1, H4a	0.035	Human
WHSC1	Wolf-Hirschhorn syndrome candidate 1	0.035
FAM190B	family with sequence similarity 190, member B	0.035
RNPS1	RNA binding protein S1, serine-rich domain	0.035
OPA1	optic atrophy 1 (autosomal dominant)	0.034
CDC5L	CDC5 cell division cycle 5-like (S. pombe)	0.034
BCL2L12	BCL2-like 12 (proline rich)	0.033
BAG1	BCL2-associated athanogene	0.033
CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	0.033
CAPRIN1	cell cycle associated protein 1	0.033
SIRT7	sirtuin 7	0.033
HIST1H2BB	histone cluster 1, H2bb	0.032
ITM2B	integral membrane protein 2B	0.032
HMGB2	high mobility group box 2	0.032
SH3KBP1	SH3-domain kinase binding protein 1	0.032
ZFAND5	zinc finger, AN1-type domain 5	0.032
MARCH5	membrane-associated ring finger (C3HC4) 5	0.032
SUFU	suppressor of fused homolog (Drosophila)	0.032
TUBB2C	tubulin, beta 2C	0.032
PAF1	Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)	0.032
HNRNPA0	heterogeneous nuclear ribonucleoprotein A0	0.031
ROD1	ROD1 regulator of differentiation 1 (S. pombe)	0.031
PFN1	profilin 1	0.031
AMBRA1	autophagy/beclin-1 regulator 1	0.030
HIST2H2AC	histone cluster 2, H2ac	0.030	Human
NCAPH	non-SMC condensin I complex, subunit H	0.030
EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4	0.030
FHL1	four and a half LIM domains 1	0.030
CHAF1B	chromatin assembly factor 1, subunit B (p60)	0.030
PHLPP2	PH domain and leucine rich repeat protein phosphatase 2	0.030
RAP1B	RAP1B, member of RAS oncogene family	0.030
BTRC	beta-transducin repeat containing	0.029
ASAP1	ArfGAP with SH3 domain, ankyrin repeat and PH domain 1	0.029
MMS22L	MMS22-like, DNA repair protein	0.029
ILF2	interleukin enhancer binding factor 2, 45kDa	0.029
DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	0.028
ESR1	estrogen receptor 1	0.028
HIST1H4I	histone cluster 1, H4i	0.028
SNX2	sorting nexin 2	0.028
VAMP3	vesicle-associated membrane protein 3 (cellubrevin)	0.028
TROAP	trophinin associated protein (tastin)	0.028
CD2AP	CD2-associated protein	0.028
ARF3	ADP-ribosylation factor 3	0.027
MAP3K4	mitogen-activated protein kinase kinase kinase 4	0.027
BMI1	BMI1 polycomb ring finger oncogene	0.027
TNIK	TRAF2 and NCK interacting kinase	0.027
IRAK3	interleukin-1 receptor-associated kinase 3	0.027
NDC80	NDC80 homolog, kinetochore complex component (S. cerevisiae)	0.027
SH3GL2	SH3-domain GRB2-like 2	0.027
UBR5	ubiquitin protein ligase E3 component n-recognin 5	0.027
GAS2L3	growth arrest-specific 2 like 3	0.026	Human
TONSL	tonsoku-like, DNA repair protein	0.026
SPAG5	sperm associated antigen 5	0.026
STRN3	striatin, calmodulin binding protein 3	0.026
RHOA	ras homolog gene family, member A	0.026
TWF2	twinfilin, actin-binding protein, homolog 2 (Drosophila)	0.026
INPP5A	inositol polyphosphate-5-phosphatase, 40kDa	0.026
STIL	SCL/TAL1 interrupting locus	0.025
ARL6IP1	ADP-ribosylation factor-like 6 interacting protein 1	0.025
KIF11	kinesin family member 11	0.025	Fly
P4HA1	prolyl 4-hydroxylase, alpha polypeptide I	0.025
TAB1	TGF-beta activated kinase 1/MAP3K7 binding protein 1	0.025
KIF15	kinesin family member 15	0.025
SMC4	structural maintenance of chromosomes 4	0.025
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.025
WASF2	WAS protein family, member 2	0.024
SRPK2	SRSF protein kinase 2	0.024
UBE2C	ubiquitin-conjugating enzyme E2C	0.024
HIST1H4J	histone cluster 1, H4j	0.024
HSPA6	heat shock 70kDa protein 6 (HSP70B')	0.024	Yeast
ABCD3	ATP-binding cassette, sub-family D (ALD), member 3	0.023
MDM2	Mdm2 p53 binding protein homolog (mouse)	0.023
SAP18	Sin3A-associated protein, 18kDa	0.023
MEOX2	mesenchyme homeobox 2	0.023
NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	0.023
ATG4B	ATG4 autophagy related 4 homolog B (S. cerevisiae)	0.023
NCAPD2	non-SMC condensin I complex, subunit D2	0.023
TRADD	TNFRSF1A-associated via death domain	0.023
ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	0.023
NCAPG	non-SMC condensin I complex, subunit G	0.023
SASS6	spindle assembly 6 homolog (C. elegans)	0.023
CENPA	centromere protein A	0.023
DUSP3	dual specificity phosphatase 3	0.023
HJURP	Holliday junction recognition protein	0.023
POLH	polymerase (DNA directed), eta	0.023
VASP	vasodilator-stimulated phosphoprotein	0.022
UFD1L	ubiquitin fusion degradation 1 like (yeast)	0.022
SLC1A5	solute carrier family 1 (neutral amino acid transporter), member 5	0.022
HABP4	hyaluronan binding protein 4	0.022
PEA15	phosphoprotein enriched in astrocytes 15	0.022
ACTN2	actinin, alpha 2	0.022
CDC27	cell division cycle 27 homolog (S. cerevisiae)	0.022
WDR1	WD repeat domain 1	0.022	Yeast Worm
PPP5C	protein phosphatase 5, catalytic subunit	0.022
TNRC6B	trinucleotide repeat containing 6B	0.022
BAZ1B	bromodomain adjacent to zinc finger domain, 1B	0.021
GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	0.021
LMNA	lamin A/C	0.021
PRKCA	protein kinase C, alpha	0.021
OBSL1	obscurin-like 1	0.021
HIST1H2AD	histone cluster 1, H2ad	0.021	Human
MAGED2	melanoma antigen family D, 2	0.021
MATR3	matrin 3	0.021
FOXM1	forkhead box M1	0.021
CNN2	calponin 2	0.021
ADAM9	ADAM metallopeptidase domain 9	0.021
UBE4B	ubiquitination factor E4B (UFD2 homolog, yeast)	0.021
RBMX	RNA binding motif protein, X-linked	0.021
HIST2H4B	histone cluster 2, H4b	0.021
FTL	ferritin, light polypeptide	0.020
PRKACB	protein kinase, cAMP-dependent, catalytic, beta	0.020
HDAC6	histone deacetylase 6	0.020
POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa	0.020
CDC34	cell division cycle 34 homolog (S. cerevisiae)	0.020
AXIN1	axin 1	0.020
UBL4A	ubiquitin-like 4A	0.020
ACTL6A	actin-like 6A	0.020
HIST1H2AH	histone cluster 1, H2ah	0.020	Human
CCDC11	coiled-coil domain containing 11	0.020
SSRP1	structure specific recognition protein 1	0.020
CALM1	calmodulin 1 (phosphorylase kinase, delta)	0.020
COTL1	coactosin-like 1 (Dictyostelium)	0.020
H3F3A	H3 histone, family 3A	0.020
HIST2H2AA3	histone cluster 2, H2aa3	0.020	Human
PPM1B	protein phosphatase, Mg2+/Mn2+ dependent, 1B	0.020
HNRNPH2	heterogeneous nuclear ribonucleoprotein H2 (H')	0.020
CAPZA1	capping protein (actin filament) muscle Z-line, alpha 1	0.020	Mouse Fly
CCNF	cyclin F	0.020
PLIN3	perilipin 3	0.020
SH3BGRL3	SH3 domain binding glutamic acid-rich protein like 3	0.020
VCL	vinculin	0.020
C6orf136	chromosome 6 open reading frame 136	0.019
TXNIP	thioredoxin interacting protein	0.019
HIST1H1D	histone cluster 1, H1d	0.019
EPS8	epidermal growth factor receptor pathway substrate 8	0.019	Mouse Worm
HNRNPF	heterogeneous nuclear ribonucleoprotein F	0.019
MYL6	myosin, light chain 6, alkali, smooth muscle and non-muscle	0.019
USP13	ubiquitin specific peptidase 13 (isopeptidase T-3)	0.019	Fly
USP15	ubiquitin specific peptidase 15	0.019
CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa	0.019
ZMYM4	zinc finger, MYM-type 4	0.019
MECP2	methyl CpG binding protein 2 (Rett syndrome)	0.019
PGAM5	phosphoglycerate mutase family member 5	0.019
ADD1	adducin 1 (alpha)	0.019
BZW1	basic leucine zipper and W2 domains 1	0.019
RPP14	ribonuclease P/MRP 14kDa subunit	0.019
PLDN	pallidin homolog (mouse)	0.019
ELAVL1	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)	0.019
SS18	synovial sarcoma translocation, chromosome 18	0.019
PPP6C	protein phosphatase 6, catalytic subunit	0.019
VRK3	vaccinia related kinase 3	0.019
MIF4GD	MIF4G domain containing	0.019
PABPN1	poly(A) binding protein, nuclear 1	0.019
CTCFL	CCCTC-binding factor (zinc finger protein)-like	0.019
HNRNPC	heterogeneous nuclear ribonucleoprotein C (C1/C2)	0.018
BCLAF1	BCL2-associated transcription factor 1	0.018
ASF1A	ASF1 anti-silencing function 1 homolog A (S. cerevisiae)	0.018	Yeast
ZFP106	zinc finger protein 106 homolog (mouse)	0.018
RTN4	reticulon 4	0.018
USP22	ubiquitin specific peptidase 22	0.018
ST3GAL3	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.018
CCDC99	coiled-coil domain containing 99	0.018
USP20	ubiquitin specific peptidase 20	0.018
SEPHS1	selenophosphate synthetase 1	0.018
VIM	vimentin	0.018
TSPO	translocator protein (18kDa)	0.018
DHRS4	dehydrogenase/reductase (SDR family) member 4	0.018
E2F1	E2F transcription factor 1	0.018
DEPDC1	DEP domain containing 1	0.018
GNAS	GNAS complex locus	0.018
KPNA2	karyopherin alpha 2 (RAG cohort 1, importin alpha 1)	0.018
SRRM1	serine/arginine repetitive matrix 1	0.018
TTK	TTK protein kinase	0.018
MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like	0.018
TMEM11	transmembrane protein 11	0.018
LXN	latexin	0.017
HIST1H1E	histone cluster 1, H1e	0.017
CWC22	CWC22 spliceosome-associated protein homolog (S. cerevisiae)	0.017
INADL	InaD-like (Drosophila)	0.017
RFX7	regulatory factor X, 7	0.017
HIST1H4L	histone cluster 1, H4l	0.017
DNM2	dynamin 2	0.017
CAPN3	calpain 3, (p94)	0.017
UIMC1	ubiquitin interaction motif containing 1	0.017
H3F3B	H3 histone, family 3B (H3.3B)	0.017
CNN1	calponin 1, basic, smooth muscle	0.017
SEPT11	septin 11	0.017
SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	0.017
CIAPIN1	cytokine induced apoptosis inhibitor 1	0.017
CHTOP	chromatin target of PRMT1	0.017
FNBP1L	formin binding protein 1-like	0.017
CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	0.017
EID1	EP300 interacting inhibitor of differentiation 1	0.017
CCT8	chaperonin containing TCP1, subunit 8 (theta)	0.017
ZMYND11	zinc finger, MYND-type containing 11	0.017
PKP2	plakophilin 2	0.017
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	0.017
MRPL41	mitochondrial ribosomal protein L41	0.017
ITSN1	intersectin 1 (SH3 domain protein)	0.017
AHNAK	AHNAK nucleoprotein	0.016
TRAF3IP1	TNF receptor-associated factor 3 interacting protein 1	0.016
GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2	0.016
SEC23A	Sec23 homolog A (S. cerevisiae)	0.016
PPP1R9B	protein phosphatase 1, regulatory (inhibitor) subunit 9B	0.016
HIST1H2BN	histone cluster 1, H2bn	0.016
CENPT	centromere protein T	0.016
KRT15	keratin 15	0.016
STX7	syntaxin 7	0.016
MUC1	mucin 1, cell surface associated	0.016
HIST1H3F	histone cluster 1, H3f	0.016
PSRC1	proline/serine-rich coiled-coil 1	0.016
CALD1	caldesmon 1	0.016
MAP3K2	mitogen-activated protein kinase kinase kinase 2	0.016
EFHD2	EF-hand domain family, member D2	0.016
STAU1	staufen, RNA binding protein, homolog 1 (Drosophila)	0.016
RRM1	ribonucleotide reductase M1	0.016
ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein	0.016
ASPM	asp (abnormal spindle) homolog, microcephaly associated (Drosophila)	0.016
EIF3F	eukaryotic translation initiation factor 3, subunit F	0.016
NPTN	neuroplastin	0.016
DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	0.016
CIT	citron (rho-interacting, serine/threonine kinase 21)	0.016
MBNL1	muscleblind-like (Drosophila)	0.016
WEE1	WEE1 homolog (S. pombe)	0.016
HSPA1L	heat shock 70kDa protein 1-like	0.016	Yeast
POLDIP3	polymerase (DNA-directed), delta interacting protein 3	0.016
HIST3H2A	histone cluster 3, H2a	0.016
ATXN3	ataxin 3	0.016
EIF4ENIF1	eukaryotic translation initiation factor 4E nuclear import factor 1	0.015
NUP62	nucleoporin 62kDa	0.015
RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	0.015
DPF2	D4, zinc and double PHD fingers family 2	0.015
MARK3	MAP/microtubule affinity-regulating kinase 3	0.015
ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	0.015
ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )	0.015
SMC1A	structural maintenance of chromosomes 1A	0.015
CAPG	capping protein (actin filament), gelsolin-like	0.015
NCF1	neutrophil cytosolic factor 1	0.015
RGS1	regulator of G-protein signaling 1	0.015
C19orf61	chromosome 19 open reading frame 61	0.015
DCUN1D4	DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)	0.015
CSRP1	cysteine and glycine-rich protein 1	0.015
KIAA1217	KIAA1217	0.015
CREB1	cAMP responsive element binding protein 1	0.015
GTF2E1	general transcription factor IIE, polypeptide 1, alpha 56kDa	0.015
ZNF414	zinc finger protein 414	0.015
RHOG	ras homolog gene family, member G (rho G)	0.015
AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	0.015
DNM1	dynamin 1	0.015
HIST1H2BL	histone cluster 1, H2bl	0.015
MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3	0.015
AP3S1	adaptor-related protein complex 3, sigma 1 subunit	0.015
TRIM37	tripartite motif containing 37	0.015
MYO1E	myosin IE	0.015
HMMR	hyaluronan-mediated motility receptor (RHAMM)	0.015
ARRB1	arrestin, beta 1	0.015
EDC3	enhancer of mRNA decapping 3 homolog (S. cerevisiae)	0.015
SLC25A13	solute carrier family 25, member 13 (citrin)	0.015
ORC1	origin recognition complex, subunit 1	0.014
PRMT2	protein arginine methyltransferase 2	0.014
CSDA	cold shock domain protein A	0.014
HIST1H3C	histone cluster 1, H3c	0.014
CASC3	cancer susceptibility candidate 3	0.014
PTPN9	protein tyrosine phosphatase, non-receptor type 9	0.014
PEX16	peroxisomal biogenesis factor 16	0.014
PIKFYVE	phosphoinositide kinase, FYVE finger containing	0.014
PEX14	peroxisomal biogenesis factor 14	0.014
CLIC1	chloride intracellular channel 1	0.014
MCM2	minichromosome maintenance complex component 2	0.014
ZC3HC1	zinc finger, C3HC-type containing 1	0.014
DHX30	DEAH (Asp-Glu-Ala-His) box polypeptide 30	0.014
RELB	v-rel reticuloendotheliosis viral oncogene homolog B	0.014
TSEN54	tRNA splicing endonuclease 54 homolog (S. cerevisiae)	0.014
HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	0.014
TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	0.014
TNNT1	troponin T type 1 (skeletal, slow)	0.014
KIF5B	kinesin family member 5B	0.014
MAP3K1	mitogen-activated protein kinase kinase kinase 1	0.014
PELI1	pellino homolog 1 (Drosophila)	0.014
TOM1L1	target of myb1 (chicken)-like 1	0.014
PPP2R1B	protein phosphatase 2, regulatory subunit A, beta	0.014
BUB1	budding uninhibited by benzimidazoles 1 homolog (yeast)	0.014
PBK	PDZ binding kinase	0.014
PINK1	PTEN induced putative kinase 1	0.014
EGLN1	egl nine homolog 1 (C. elegans)	0.014
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.014
VDAC1	voltage-dependent anion channel 1	0.014
PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	0.014
EIF1	eukaryotic translation initiation factor 1	0.014
MOBKL1A	MOB1, Mps One Binder kinase activator-like 1A (yeast)	0.014
CSNK1G2	casein kinase 1, gamma 2	0.014
CHD4	chromodomain helicase DNA binding protein 4	0.014
MAGED1	melanoma antigen family D, 1	0.014
TOP2A	topoisomerase (DNA) II alpha 170kDa	0.014
RAB1B	RAB1B, member RAS oncogene family	0.014
HIST1H3I	histone cluster 1, H3i	0.013
CAV2	caveolin 2	0.013
YAP1	Yes-associated protein 1	0.013
ACTC1	actin, alpha, cardiac muscle 1	0.013
AXIN2	axin 2	0.013
TCAP	titin-cap (telethonin)	0.013
KCNQ1	potassium voltage-gated channel, KQT-like subfamily, member 1	0.013
TEKT4	tektin 4	0.013
KIF22	kinesin family member 22	0.013
ASF1B	ASF1 anti-silencing function 1 homolog B (S. cerevisiae)	0.013	Yeast
PRUNE	prune homolog (Drosophila)	0.013
CTTNBP2NL	CTTNBP2 N-terminal like	0.013
PAX3	paired box 3	0.013
CHMP4C	chromatin modifying protein 4C	0.013
DHX29	DEAH (Asp-Glu-Ala-His) box polypeptide 29	0.013
ACD	adrenocortical dysplasia homolog (mouse)	0.013
GPRASP2	G protein-coupled receptor associated sorting protein 2	0.013
UTRN	utrophin	0.013
EDC4	enhancer of mRNA decapping 4	0.013
PPP2R2C	protein phosphatase 2, regulatory subunit B, gamma	0.013
THBS1	thrombospondin 1	0.013
SKA1	spindle and kinetochore associated complex subunit 1	0.013
GLOD4	glyoxalase domain containing 4	0.013
RAB11A	RAB11A, member RAS oncogene family	0.013
DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4	0.013
LIN37	lin-37 homolog (C. elegans)	0.013
TRAF2	TNF receptor-associated factor 2	0.013
FTH1	ferritin, heavy polypeptide 1	0.013
MAP7D1	MAP7 domain containing 1	0.013
ERN1	endoplasmic reticulum to nucleus signaling 1	0.013
FTSJ1	FtsJ homolog 1 (E. coli)	0.013
CNOT8	CCR4-NOT transcription complex, subunit 8	0.013
HPCAL1	hippocalcin-like 1	0.013
MUL1	mitochondrial E3 ubiquitin protein ligase 1	0.013
MAPRE2	microtubule-associated protein, RP/EB family, member 2	0.013
VAMP2	vesicle-associated membrane protein 2 (synaptobrevin 2)	0.013
MAEA	macrophage erythroblast attacher	0.013
ACAP3	ArfGAP with coiled-coil, ankyrin repeat and PH domains 3	0.013
FUS	fused in sarcoma	0.013
TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A	0.013
UBE3C	ubiquitin protein ligase E3C	0.013
TMEM30A	transmembrane protein 30A	0.013
FAM64A	family with sequence similarity 64, member A	0.013
KIF23	kinesin family member 23	0.013
G2E3	G2/M-phase specific E3 ubiquitin protein ligase	0.013
STAMBP	STAM binding protein	0.013
U2AF1	U2 small nuclear RNA auxiliary factor 1	0.012
GULP1	GULP, engulfment adaptor PTB domain containing 1	0.012
FAM89B	family with sequence similarity 89, member B	0.012
DCTN1	dynactin 1	0.012
ITGA6	integrin, alpha 6	0.012
ZC3H12C	zinc finger CCCH-type containing 12C	0.012
CHD7	chromodomain helicase DNA binding protein 7	0.012
PUM2	pumilio homolog 2 (Drosophila)	0.012
KIAA1539	KIAA1539	0.012
KIFAP3	kinesin-associated protein 3	0.012
PELI2	pellino homolog 2 (Drosophila)	0.012
OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	0.012
PPP2R5B	protein phosphatase 2, regulatory subunit B', beta	0.012
HIST1H3J	histone cluster 1, H3j	0.012
NEK6	NIMA (never in mitosis gene a)-related kinase 6	0.012
TLR2	toll-like receptor 2	0.012
TUBB8	tubulin, beta 8	0.012
CNOT6	CCR4-NOT transcription complex, subunit 6	0.012
DBN1	drebrin 1	0.012
HMGB3	high mobility group box 3	0.012
HERC3	hect domain and RLD 3	0.012
AAK1	AP2 associated kinase 1	0.012
PKMYT1	protein kinase, membrane associated tyrosine/threonine 1	0.012
CRNKL1	crooked neck pre-mRNA splicing factor-like 1 (Drosophila)	0.012
DYNLT3	dynein, light chain, Tctex-type 3	0.012
WNK1	WNK lysine deficient protein kinase 1	0.012
HMGB1	high mobility group box 1	0.012
ITGB5	integrin, beta 5	0.012
EXOC1	exocyst complex component 1	0.012
PKM2	pyruvate kinase, muscle	0.012
RHOC	ras homolog gene family, member C	0.012
PPIA	peptidylprolyl isomerase A (cyclophilin A)	0.012
GNB1	guanine nucleotide binding protein (G protein), beta polypeptide 1	0.012
TRIM2	tripartite motif containing 2	0.012
HSPA2	heat shock 70kDa protein 2	0.012	Yeast
GIGYF2	GRB10 interacting GYF protein 2	0.012
DES	desmin	0.012
UNKL	unkempt homolog (Drosophila)-like	0.012
TRAK2	trafficking protein, kinesin binding 2	0.012
TMPO	thymopoietin	0.012
ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	0.012
TOLLIP	toll interacting protein	0.012
CDC25A	cell division cycle 25 homolog A (S. pombe)	0.012
SYNE1	spectrin repeat containing, nuclear envelope 1	0.012
FHL2	four and a half LIM domains 2	0.012
HIST4H4	histone cluster 4, H4	0.012
FKBP1A	FK506 binding protein 1A, 12kDa	0.012
ACTR3	ARP3 actin-related protein 3 homolog (yeast)	0.012
UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)	0.012
RAD23B	RAD23 homolog B (S. cerevisiae)	0.012
LBR	lamin B receptor	0.012
AP3D1	adaptor-related protein complex 3, delta 1 subunit	0.012
GNG12	guanine nucleotide binding protein (G protein), gamma 12	0.012
KLF5	Kruppel-like factor 5 (intestinal)	0.012	Fly
ACTN4	actinin, alpha 4	0.012
RPRD2	regulation of nuclear pre-mRNA domain containing 2	0.012
MAPT	microtubule-associated protein tau	0.012
RBM22	RNA binding motif protein 22	0.012
PEX26	peroxisomal biogenesis factor 26	0.012
DYNC1H1	dynein, cytoplasmic 1, heavy chain 1	0.012
TUBG1	tubulin, gamma 1	0.012
CDC6	cell division cycle 6 homolog (S. cerevisiae)	0.012
CSTF2	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa	0.012
CBFB	core-binding factor, beta subunit	0.012
SMG7	Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans)	0.011
ZBED4	zinc finger, BED-type containing 4	0.011
FER	fer (fps/fes related) tyrosine kinase	0.011
CWC15	CWC15 spliceosome-associated protein homolog (S. cerevisiae)	0.011
GSK3B	glycogen synthase kinase 3 beta	0.011
ITGA2	integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)	0.011
ANXA2	annexin A2	0.011
GBE1	glucan (1,4-alpha-), branching enzyme 1	0.011
DCK	deoxycytidine kinase	0.011
KIFC1	kinesin family member C1	0.011
MIS18BP1	MIS18 binding protein 1	0.011
PPARG	peroxisome proliferator-activated receptor gamma	0.011
DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)	0.011
ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c	0.011
LYPLA2	lysophospholipase II	0.011
KIF18A	kinesin family member 18A	0.011
NAT15	N-acetyltransferase 15 (GCN5-related, putative)	0.011
HIST1H4F	histone cluster 1, H4f	0.011
UBE2J2	ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast)	0.011
NUF2	NUF2, NDC80 kinetochore complex component, homolog (S. cerevisiae)	0.011
C3orf19	chromosome 3 open reading frame 19	0.011
WDR67	WD repeat domain 67	0.011
BIRC6	baculoviral IAP repeat containing 6	0.011
ADAM10	ADAM metallopeptidase domain 10	0.011
BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	0.011
NOMO1	NODAL modulator 1	0.011
CEBPB	CCAAT/enhancer binding protein (C/EBP), beta	0.011
STX12	syntaxin 12	0.011
ARL15	ADP-ribosylation factor-like 15	0.011
HNRNPH1	heterogeneous nuclear ribonucleoprotein H1 (H)	0.011
BEND5	BEN domain containing 5	0.011
TRIO	triple functional domain (PTPRF interacting)	0.011
HSD17B11	hydroxysteroid (17-beta) dehydrogenase 11	0.011
ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)	0.011
ANAPC1	anaphase promoting complex subunit 1	0.011
ANP32A	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	0.011
ERBB2IP	erbb2 interacting protein	0.011
USP24	ubiquitin specific peptidase 24	0.011
CHAF1A	chromatin assembly factor 1, subunit A (p150)	0.011
PTK6	PTK6 protein tyrosine kinase 6	0.011
RAB5C	RAB5C, member RAS oncogene family	0.011
DTNBP1	dystrobrevin binding protein 1	0.011
NEK4	NIMA (never in mitosis gene a)-related kinase 4	0.011
ANK2	ankyrin 2, neuronal	0.011
DEK	DEK oncogene	0.011
HIST1H1B	histone cluster 1, H1b	0.011
ORC6	origin recognition complex, subunit 6	0.011
DUSP1	dual specificity phosphatase 1	0.011
ALDH7A1	aldehyde dehydrogenase 7 family, member A1	0.011
CAMKV	CaM kinase-like vesicle-associated	0.011
UPF3A	UPF3 regulator of nonsense transcripts homolog A (yeast)	0.011
TRIM54	tripartite motif containing 54	0.011	Mouse
TCTEX1D2	Tctex1 domain containing 2	0.011
MAPK1	mitogen-activated protein kinase 1	0.011
C17orf71	chromosome 17 open reading frame 71	0.011
RBM3	RNA binding motif (RNP1, RRM) protein 3	0.011
FBXO30	F-box protein 30	0.011
EIF4G2	eukaryotic translation initiation factor 4 gamma, 2	0.011
PPIP5K2	diphosphoinositol pentakisphosphate kinase 2	0.011
FBXO25	F-box protein 25	0.011
TOPBP1	topoisomerase (DNA) II binding protein 1	0.011
MAPRE3	microtubule-associated protein, RP/EB family, member 3	0.011
PTDSS1	phosphatidylserine synthase 1	0.011
PPP6R1	protein phosphatase 6, regulatory subunit 1	0.011
CAPZB	capping protein (actin filament) muscle Z-line, beta	0.011	Yeast Fly
TLR4	toll-like receptor 4	0.011
PAIP1	poly(A) binding protein interacting protein 1	0.011
PHF10	PHD finger protein 10	0.011
LASP1	LIM and SH3 protein 1	0.011
PYROXD2	pyridine nucleotide-disulphide oxidoreductase domain 2	0.011
SYT11	synaptotagmin XI	0.011
ARAP3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	0.010
TRAPPC1	trafficking protein particle complex 1	0.010
KIAA1549	KIAA1549	0.010
VAV3	vav 3 guanine nucleotide exchange factor	0.010
ZBTB6	zinc finger and BTB domain containing 6	0.010
STMN2	stathmin-like 2	0.010
MYO1G	myosin IG	0.010
CP110	CP110 protein	0.010
ATAD2B	ATPase family, AAA domain containing 2B	0.010
BRD2	bromodomain containing 2	0.010
AKAP11	A kinase (PRKA) anchor protein 11	0.010
MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2	0.010
MXI1	MAX interactor 1	0.010
GADD45G	growth arrest and DNA-damage-inducible, gamma	0.010
SEPT10	septin 10	0.010
AURKA	aurora kinase A	0.010
MYL12B	myosin, light chain 12B, regulatory	0.010
C13orf34	chromosome 13 open reading frame 34	0.010
SNX18	sorting nexin 18	0.010
TUBB6	tubulin, beta 6	0.010
CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase	0.010
AQR	aquarius homolog (mouse)	0.010
HIST1H3E	histone cluster 1, H3e	0.010
DST	dystonin	0.010	Fly
UPF2	UPF2 regulator of nonsense transcripts homolog (yeast)	0.010
UBB	ubiquitin B	0.010
PRKD1	protein kinase D1	0.010
EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2	0.010
PI4KB	phosphatidylinositol 4-kinase, catalytic, beta	0.010
MDM1	Mdm1 nuclear protein homolog (mouse)	0.010
RPH3AL	rabphilin 3A-like (without C2 domains)	0.010
PEX11B	peroxisomal biogenesis factor 11 beta	0.010
BCL2A1	BCL2-related protein A1	0.010
HIST1H4C	histone cluster 1, H4c	0.010
C22orf39	chromosome 22 open reading frame 39	0.010
CDC123	cell division cycle 123 homolog (S. cerevisiae)	0.010
BCL2L1	BCL2-like 1	0.010
TMSB10	thymosin beta 10	0.010
IRAK4	interleukin-1 receptor-associated kinase 4	0.010
TNFAIP2	tumor necrosis factor, alpha-induced protein 2	0.010
PTPN23	protein tyrosine phosphatase, non-receptor type 23	0.010
HDAC2	histone deacetylase 2	0.010
YTHDC2	YTH domain containing 2	0.010
YWHAH	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide	0.010
EIF4G3	eukaryotic translation initiation factor 4 gamma, 3	0.010
SAC3D1	SAC3 domain containing 1	0.010
CBWD2	COBW domain containing 2	0.010
FAM193A	family with sequence similarity 193, member A	0.010
NASP	nuclear autoantigenic sperm protein (histone-binding)	0.010