IMP: Integrative Multi-species Prediction

Homo sapiens

30 genes annotated in human

positive regulation of mitochondrion organization

Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.

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Known genes in the process in humanInclude functional analogs

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Gene Predictions

Click on a gene's description to view its network relationships with genes known to be involved in "positive regulation of mitochondrion organization"

Show only novel predictionsShow only unknown genesHighlight genes with functional analogs involved in "positive regulation of mitochondrion organization" (in gray)

Name	Description	Probability	Func Analog Organism
BCL2	B-cell CLL/lymphoma 2	1.000	Human Worm
BCL2L1	BCL2-like 1	1.000	Human
BCL2L11	BCL2-like 11 (apoptosis facilitator)	1.000
BAX	BCL2-associated X protein	0.997
MCL1	myeloid cell leukemia sequence 1 (BCL2-related)	0.988	Human Worm
BAD	BCL2-associated agonist of cell death	0.929
BNIP3	BCL2/adenovirus E1B 19kDa interacting protein 3	0.918
BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like	0.841	Human
TP53BP2	tumor protein p53 binding protein, 2	0.834
BID	BH3 interacting domain death agonist	0.799
MAP1LC3B	microtubule-associated protein 1 light chain 3 beta	0.766
BECN1	beclin 1, autophagy related	0.751
BAK1	BCL2-antagonist/killer 1	0.751	Human Rat
DNM1L	dynamin 1-like	0.737
TNFRSF6B	tumor necrosis factor receptor superfamily, member 6b, decoy	0.683
PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1	0.605
SMCR7L	Smith-Magenis syndrome chromosome region, candidate 7-like	0.582
GADD45A	growth arrest and DNA-damage-inducible, alpha	0.569
VDAC2	voltage-dependent anion channel 2	0.544
FKBP8	FK506 binding protein 8, 38kDa	0.294
BBC3	BCL2 binding component 3	0.244
ESRRG	estrogen-related receptor gamma	0.211
PXMP2	peroxisomal membrane protein 2, 22kDa	0.203
MFN2	mitofusin 2	0.190
ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	0.187
PPARG	peroxisome proliferator-activated receptor gamma	0.183
BBS10	Bardet-Biedl syndrome 10	0.178
TNFRSF10A	tumor necrosis factor receptor superfamily, member 10a	0.167
MEFV	Mediterranean fever	0.165
SMCR7	Smith-Magenis syndrome chromosome region, candidate 7	0.159
ICT1	immature colon carcinoma transcript 1	0.152
GRPEL1	GrpE-like 1, mitochondrial (E. coli)	0.145
NLRC4	NLR family, CARD domain containing 4	0.140
WWOX	WW domain containing oxidoreductase	0.139
RNF11	ring finger protein 11	0.102
SNX9	sorting nexin 9	0.100
NR4A1	nuclear receptor subfamily 4, group A, member 1	0.098
C12orf62	chromosome 12 open reading frame 62	0.097
ZNF746	zinc finger protein 746	0.088
BIK	BCL2-interacting killer (apoptosis-inducing)	0.081
VDAC1	voltage-dependent anion channel 1	0.073
ZFYVE1	zinc finger, FYVE domain containing 1	0.073
SQSTM1	sequestosome 1	0.069
TMEM11	transmembrane protein 11	0.061
LMO4	LIM domain only 4	0.059
MAGEH1	melanoma antigen family H, 1	0.056
SATB2	SATB homeobox 2	0.054
MARCH5	membrane-associated ring finger (C3HC4) 5	0.053
KRT5	keratin 5	0.050
CABLES1	Cdk5 and Abl enzyme substrate 1	0.049
FIS1	fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)	0.048
PHB	prohibitin	0.046
AMBRA1	autophagy/beclin-1 regulator 1	0.044
UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	0.044
HUWE1	HECT, UBA and WWE domain containing 1	0.044
ZFAND5	zinc finger, AN1-type domain 5	0.043
MKRN1	makorin ring finger protein 1	0.041
TNFRSF14	tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)	0.041
GBP2	guanylate binding protein 2, interferon-inducible	0.040
MRPS7	mitochondrial ribosomal protein S7	0.039
TIMM23	translocase of inner mitochondrial membrane 23 homolog (yeast) and translocase of inner mitochondrial membrane 23 homolog (yeast)	0.037
C1orf93	chromosome 1 open reading frame 93	0.037
BCL2L2	BCL2-like 2	0.036	Worm
TACO1	translational activator of mitochondrially encoded cytochrome c oxidase I	0.036
DCTN3	dynactin 3 (p22)	0.035
MDM4	Mdm4 p53 binding protein homolog (mouse)	0.035
RNF144B	ring finger protein 144B	0.035
NAF1	nuclear assembly factor 1 homolog (S. cerevisiae)	0.034
MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha	0.034
BCAP31	B-cell receptor-associated protein 31	0.034
NBR1	neighbor of BRCA1 gene 1	0.034
PGK1	phosphoglycerate kinase 1	0.030
CASP1	caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)	0.028
YPEL5	yippee-like 5 (Drosophila)	0.026
CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	0.025
HRK	harakiri, BCL2 interacting protein (contains only BH3 domain)	0.025
TOMM22	translocase of outer mitochondrial membrane 22 homolog (yeast)	0.024
UBASH3B	ubiquitin associated and SH3 domain containing B	0.024
PDCD2	programmed cell death 2	0.024
C6orf108	chromosome 6 open reading frame 108	0.024
CASP8	caspase 8, apoptosis-related cysteine peptidase	0.024
AXIN1	axin 1	0.023
KRT6C	keratin 6C	0.023
MAPK8	mitogen-activated protein kinase 8	0.022
HAGH	hydroxyacylglutathione hydrolase	0.022
PACSIN1	protein kinase C and casein kinase substrate in neurons 1	0.022
RNR2	l-rRNA	0.021
GNB5	guanine nucleotide binding protein (G protein), beta 5	0.021
WT1	Wilms tumor 1	0.021
SGK3	serum/glucocorticoid regulated kinase family, member 3	0.019
PEX19	peroxisomal biogenesis factor 19	0.019
KBTBD7	kelch repeat and BTB (POZ) domain containing 7	0.019
UBASH3A	ubiquitin associated and SH3 domain containing A	0.019
MRPL14	mitochondrial ribosomal protein L14	0.018
UBE2I	ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)	0.018
SPNS1	spinster homolog 1 (Drosophila)	0.018
POLH	polymerase (DNA directed), eta	0.018
ELK1	ELK1, member of ETS oncogene family	0.018
EWSR1	Ewing sarcoma breakpoint region 1	0.017
PDPK1	3-phosphoinositide dependent protein kinase-1	0.017
BABAM1	BRISC and BRCA1 A complex member 1	0.017
ZRANB1	zinc finger, RAN-binding domain containing 1	0.017
CLU	clusterin	0.016
KLF5	Kruppel-like factor 5 (intestinal)	0.016
RABAC1	Rab acceptor 1 (prenylated)	0.016
FUS	fused in sarcoma	0.016
POLR2J	polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa	0.016
HSPA9	heat shock 70kDa protein 9 (mortalin)	0.016
FAM158A	family with sequence similarity 158, member A	0.016
HDAC6	histone deacetylase 6	0.016
SRGAP2	SLIT-ROBO Rho GTPase activating protein 2	0.015
UVRAG	UV radiation resistance associated gene	0.015
DTX1	deltex homolog 1 (Drosophila)	0.015
NMI	N-myc (and STAT) interactor	0.015
FAM190B	family with sequence similarity 190, member B	0.015
ING2	inhibitor of growth family, member 2	0.015
PRMT1	protein arginine methyltransferase 1	0.015
MRPS15	mitochondrial ribosomal protein S15	0.014
KIAA1377	KIAA1377	0.014
TMEM183B	transmembrane protein 183B	0.014
PRKRA	protein kinase, interferon-inducible double stranded RNA dependent activator	0.014
ZHX1	zinc fingers and homeoboxes 1	0.014
PSEN2	presenilin 2 (Alzheimer disease 4)	0.014
MRPS24	mitochondrial ribosomal protein S24	0.014
UCK2	uridine-cytidine kinase 2	0.014
ZC3HC1	zinc finger, C3HC-type containing 1	0.014
DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)	0.014
YAP1	Yes-associated protein 1	0.014
KLHDC2	kelch domain containing 2	0.013
FAM82A2	family with sequence similarity 82, member A2	0.013
S1PR5	sphingosine-1-phosphate receptor 5	0.013
PACSIN3	protein kinase C and casein kinase substrate in neurons 3	0.013
RANGAP1	Ran GTPase activating protein 1	0.013
ME2	malic enzyme 2, NAD(+)-dependent, mitochondrial	0.013
FTH1	ferritin, heavy polypeptide 1	0.013
NAP1L5	nucleosome assembly protein 1-like 5	0.013
C19orf25	chromosome 19 open reading frame 25	0.013
IFI44	interferon-induced protein 44	0.013
SURF1	surfeit 1	0.012
COMMD1	copper metabolism (Murr1) domain containing 1	0.012
MXI1	MAX interactor 1	0.012
DUSP23	dual specificity phosphatase 23	0.012
FNBP1	formin binding protein 1	0.012
FAM134A	family with sequence similarity 134, member A	0.012
FASTKD5	FAST kinase domains 5	0.012
HNRNPCL1	heterogeneous nuclear ribonucleoprotein C-like 1	0.012
SNCA	synuclein, alpha (non A4 component of amyloid precursor)	0.012
FES	feline sarcoma oncogene	0.012
TRIM14	tripartite motif containing 14	0.011
ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	0.011
DDT	D-dopachrome tautomerase	0.011
SF3B5	splicing factor 3b, subunit 5, 10kDa	0.011
PLSCR1	phospholipid scramblase 1	0.011
TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1	0.011
GOT1	glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)	0.011
METTL23	methyltransferase like 23	0.011
FASN	fatty acid synthase	0.011
TNFRSF10B	tumor necrosis factor receptor superfamily, member 10b	0.011
PACSIN2	protein kinase C and casein kinase substrate in neurons 2	0.011
SF3B3	splicing factor 3b, subunit 3, 130kDa	0.011
C8orf33	chromosome 8 open reading frame 33	0.011
EIF1	eukaryotic translation initiation factor 1	0.010
SNX3	sorting nexin 3	0.010
BCL2L12	BCL2-like 12 (proline rich)	0.010
RIOK3	RIO kinase 3 (yeast)	0.010
PPIF	peptidylprolyl isomerase F	0.010	Mouse
TNKS	tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase	0.010
NOP16	NOP16 nucleolar protein homolog (yeast)	0.010
CMC1	COX assembly mitochondrial protein homolog (S. cerevisiae)	0.010
CFLAR	CASP8 and FADD-like apoptosis regulator	0.010
VKORC1	vitamin K epoxide reductase complex, subunit 1	0.010
NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1	0.010